CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [RCB1189 : THP-1]

4951 Tsuchiya S, Minegishi N, Minegishi M, Sato T, Konno T. Adaptation of a human monocytic leukemia cell line (THP-1) in a protein-free chemically defined medium. Tohoku J Exp Med 1986 150(4):455-65 PubMed ID: 3551191 DOI: 10.1620/tjem.150.455

4950 Tajima S, Hayashi R, Tsuchiya S, Miyake Y, Yamamoto A. Cells of a human monocytic leukemia cell line (THP-1) synthesize and secrete apolipoprotein E and lipoprotein lipase. Biochem Biophys Res Commun 1985 126(1):526-31 PubMed ID: 3855620 DOI: 10.1016/0006-291x(85)90637-0

4949 Tsuchiya S, Kobayashi Y, Goto Y, Okumura H, Nakae S, Konno T, Tada K. Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester. Cancer Res 1982 42(4):1530-6 PubMed ID: 6949641

720 Tsuchiya S, Yamabe M, Yamaguchi Y, Kobayashi Y, Konno T, Tada K. Establishment and characterization of a human acute monocytic leukemia cell line (THP-1). Int J Cancer 1980 26(2):171-6 PubMed ID: 6970727 DOI: 10.1002/ijc.2910260208

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19827 Yoshioka D, Nakamura T, Kubota Y, Takekawa M. Formation of the NLRP3 inflammasome inhibits stress granule assembly by multiple mechanisms J Biochem 2024 Jan 31:mvae009 PubMed ID: 38299728 DOI: 10.1093/jb/mvae009

21574 Kawakami K, Fukuda T, Toyoda M, Nakao Y, Hayashi C, Watanabe Y, Aoki T, Shinjo T, Iwashita M, Yamashita A, Shida M, Sanui T, Uchiumi T, Nishimura F. Luteolin Is a Potential Immunomodulating Natural Compound against Pulpal Inflammation. Biomed Res Int 2024 2024:8864513 PubMed ID: 38304347 DOI: 10.1155/2024/8864513

21592 Ito F, Yanatori I, Kato K, Toyokuni S. Protocol for the isolation of GFP-expressing ferroptosis-dependent extracellular vesicles in in vitro cell culture models. STAR Protoc 2024 5(1):102892 PubMed ID: 38363686 DOI: 10.1016/j.xpro.2024.102892

21650 Matsuo H, Inagami A, Ito Y, Ito N, Iyoda S, Harata Y, Higashitani M, Shoji K, Tanaka M, Noura M, Mikami T, Kato I, Takita J, Nakahata T, Adachi S. Parbendazole as a promising drug for inducing differentiation of acute myeloid leukemia cells with various subtypes. Commun Biol 2024 7(1):123 PubMed ID: 38267545 DOI: 10.1038/s42003-024-05811-8

21651 Tatsuno R, Ichikawa J, Komohara Y, Pan C, Kawasaki T, Enomoto A, Aoki K, Hayakawa K, Iwata S, Jubashi T, Haro H. Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway. Cell Death Dis 2024 15(2):108 PubMed ID: 38302407 DOI: 10.1038/s41419-024-06487-y

22152 Yamamori Y, Shirai R, Ohkura K, Nagamune H, Tomoyasu T, Tabata A. Streptolysin S induces proinflammatory cytokine expression in calcium ion-influx-dependent manner. Curr Res Microb Sci 2024 7:100265 PubMed ID: 39211836 DOI: 10.1016/j.crmicr.2024.100265

17688 Washisaka T, Tabata Y. Live Imaging of Monocyte/Macrophage Differentiation with Cationized Gelatin Nanospheres Incorporating a Molecular Beacon ACS Biomater Sci Eng 2023 Apr 4 PubMed ID: 37014020 DOI: 10.1021/acsbiomaterials.2c01420

19580 Murokawa H, Egusa K, Shibutani S, Iwata H. Mechanistic/mammalian target of rapamycin complex 1 (mTORC1) signaling is involved in phagocytosis activation during THP-1 cell differentiation J Vet Med Sci 2023 85(7):772-780 PubMed ID: 37225457 DOI: 10.1292/jvms.22-0504

19871 Yamada M, Nitta Y, Uehara T, Suzuki H, Miya F, Takenouchi T, Tamura M, Ayabe S, Yoshiki A, Maeno A, Saga Y, Furuse T, Yamada I, Okamoto N, Kosaki K, Sugie A. Heterozygous loss-of-function DHX9 variants are associated with neurodevelopmental disorders: Human genetic and experimental evidences Eur J Med Genet 2023 66(8):104804 PubMed ID: 37369308 DOI: 10.1016/j.ejmg.2023.104804

21116 Komuro R, Honda Y, Yanaizu M, Nagahama M, Kino Y. Alzheimer's Disease-Associated Alternative Splicing of CD33 Is Regulated by the HNRNPA Family Proteins. Cells 2023 12(4) PubMed ID: 36831269 DOI: 10.3390/cells12040602

21363 Unzai T, Washisaka T, Tabata Y. An artificial silk elastin-like protein modifies the polarization of human macrophages line THP-1. J Biomater Appl 2023 8853282231192186 PubMed ID: 37494553 DOI: 10.1177/08853282231192186

21394 Egusa K, Shibutani S, Iwata H. IgG and insulin enhance endocytosis in THP-1 cells via activation of phosphatidylinositol 3-kinase (PI3K). Biochem Biophys Res Commun 2023 679:160-166 PubMed ID: 37696069 DOI: 10.1016/j.bbrc.2023.09.008

21518 Hirata W, Itatani Y, Masui H, Kawada K, Mizuno R, Yamamoto T, Okamoto T, Ogawa R, Inamoto S, Maekawa H, Okamura R, Kiyasu Y, Hanada K, Okamoto M, Nishikawa Y, Sugimoto N, Tamura T, Hatano E, Sakai Y, Obama K. Downregulation of osteoprotegerin in colorectal cancer cells promotes liver metastasis via activating tumor-associated macrophage. Sci Rep 2023 13(1):22217 PubMed ID: 38097649 DOI: 10.1038/s41598-023-49312-w

17691 Ushio S, Wada Y, Nakamura M, Matsumoto D, Hoshika K, Shiromizu S, Iwata N, Esumi S, Kajizono M, Kitamura Y, Sendo T. Anxiolytic-like effects of hochuekkito in lipopolysaccharide-treated mice involve interleukin-6 inhibition Front Pharmacol 2022 13:890048 PubMed ID: 36034871 DOI: 10.3389/fphar.2022.890048

20632 Kasai F, Hirayama N, Fukushima M, Kohara A, Nakamura Y. THP-1 reference data: proposal of an in vitro branched evolution model for cancer cell lines. Int J Cancer 2022 PubMed ID: 35373342 DOI: 10.1002/ijc.34019

16920 Ikegami H, Yamasaki K, Ogawa M, Nemoto K, Akata K, Noguchi S, Fukuda K, Kawanami T, Mukae H, Yatera K. Reduced phagocytic activity of human alveolar macrophages infected with Mycobacterium avium complex J Infect Chemother 2022 Aug 1 PubMed ID: 35926765 DOI: 10.1016/j.jiac.2022.07.018

16971 Kawase A, Takashima O, Tanaka S, Shimada H, Iwaki M. Diclofenac-Induced Cytotoxicity in Direct and Indirect Co-Culture of HepG2 Cells with Differentiated THP-1 Cells Int J Mol Sci 2022 23(15):8660 PubMed ID: 35955793 DOI: 10.3390/ijms23158660

20842 Tabata A, Matsumoto A, Fujimoto A, Ohkura K, Ikeda T, Oda H, Yokohata S, Kobayashi M, Tomoyasu T, Takao A, Ohkuni H, Nagamune H. Dual functions of discoidinolysin, a cholesterol-dependent cytolysin with N-terminal discoidin domain produced from Streptococcus mitis strain Nm-76. J Oral Microbiol 2022 14(1):2105013 PubMed ID: 35937899 DOI: 10.1080/20002297.2022.2105013

20897 Ito M, Maejima Y, Nishimura K, Nakae Y, Ono A, Iwaki-Egawa S. A role for N-glycosylation in active adenosine deaminase 2 production. Biochim Biophys Acta Gen Subj 2022 1866(12):130237 PubMed ID: 36029899 DOI: 10.1016/j.bbagen.2022.130237

20957 Yokohata S, Ohkura K, Nagamune H, Tomoyasu T, Tabata A. Human serum albumin stabilizes streptolysin S activity secreted in the extracellular milieu by streptolysin S-producing streptococci. Microbiol Immunol 2022 PubMed ID: 36478453 DOI: 10.1111/1348-0421.13042

13032 Kanai R, Nakashima A, Doi S, Kimura T, Yoshida K, Maeda S, Ishiuchi N, Yamada Y, Ike T, Doi T, Kato Y, Masaki T. Interferon-γ enhances the therapeutic effect of mesenchymal stem cells on experimental renal fibrosis. Sci Rep 2021 PubMed ID: 33441701 DOI: 10.1038/s41598-020-79664-6

13296 Nakatani K, Matsuo H, Harata Y, Higashitani M, Koyama A, Noura M, Nishinaka-Arai Y, Kamikubo Y, Adachi S. Inhibition of CDK4/6 and autophagy synergistically induces apoptosis in t(8;21) acute myeloid leukemia cells. Int J Hematol 2021 113(2):243-253 PubMed ID: 33068248 DOI: 10.1007/s12185-020-03015-4

13347 Fujita M, Yamamoto H, Yoshida N, Ono R, Matsuoka T, Kihara S. Atheroprotective Roles of Adiponectin via CCL2 Inhibition. J Atheroscler Thromb 2021 28(11):1204-1213 PubMed ID: 33191365 DOI: 10.5551/jat.58875

13382 Li H, Somiya M, Kuroda S. Enhancing antibody-dependent cellular phagocytosis by Re-education of tumor-associated macrophages with resiquimod-encapsulated liposomes. Biomaterials 2021 PubMed ID: 33338932 DOI: 10.1016/j.biomaterials.2020.120601

13541 Itoh K, Shigemi H, Chihara K, Sada K, Yamauchi T, Iwasaki H. Caspofungin suppresses zymosan-induced cytokine and chemokine release in THP-1 cells: possible involvement of the spleen tyrosine kinase pathway Transl Res 2021 227:53-63 PubMed ID: 32687976 DOI: 10.1016/j.trsl.2020.07.005

20199 Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S. Extracellular mRNA transported to the nucleus exerts translation-independent function. Nat Commun 2021 12(1):3655 PubMed ID: 34135341 DOI: 10.1038/s41467-021-23969-1

20239 Kawakatsu K, Maemura M, Seta Y, Nishikata T. Involvement of Annexin A2 in Serum-MAF Dependent Phagocytic Activation of Macrophages. Anticancer Res 2021 41(8):4089-4092 PubMed ID: 34281879 DOI: 10.21873/anticanres.15211

15109 Minoru Sasaki, Yu Shimoyama, Yoshitoyo Kodama, Taichi Ishikawa Abiotrophia defectiva DnaK Promotes Fibronectin-Mediated Adherence to HUVECs and Induces a Proinflammatory Response International Journal of Molecular Sciences 2021 22(8528) PubMed ID: 34445234 DOI: 10.3390/ijms22168528

15492 Lee S, Ishitsuka A, Kuroki T, Lin YH, Shibuya A, Hongu T, Funakoshi Y, Kanaho Y, Nagata K, Kawaguchi A. Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes JCI Insight 2021 6(16):e139190 PubMed ID: 34423792 DOI: 10.1172/jci.insight.139190

20374 Kato S, Arasaki K, Tokutomi N, Imai Y, Inoshita T, Hattori N, Sasaki T, Sato M, Wakana Y, Inoue H, Tagaya M. Syntaxin 17, an ancient SNARE paralog, plays different and conserved roles in different organisms. J Cell Sci 2021 PubMed ID: 34704591 DOI: 10.1242/jcs.258699

20487 Sakamaki I, Fukushi M, Ohashi W, Tanaka Y, Itoh K, Tomihara K, Yamamoto Y, Iwasaki H. Sitafloxacin reduces tumor necrosis factor alpha (TNFα) converting enzyme (TACE) phosphorylation and activity to inhibit TNFα release from lipopolysaccharide-stimulated THP-1 cells. Sci Rep 2021 11(1):24154 PubMed ID: 34921186 DOI: 10.1038/s41598-021-03511-5

20490 Ito F, Kato K, Yanatori I, Murohara T, Toyokuni S. Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin. Redox Biol 2021 47:102174 PubMed ID: 34700146 DOI: 10.1016/j.redox.2021.102174

20561 Sasaki M, Shimoyama Y, Kodama Y, Ishikawa T. Tryptophanyl tRNA Synthetase from Human Macrophages Infected by Porphyromonas gingivalis Induces a Proinflammatory Response Associated with Atherosclerosis. Pathogens 2021 10(12) PubMed ID: 34959604 DOI: 10.3390/pathogens10121648

10948 Karen Yotsumoto, Terukazu Sanui, Urara Tanaka, Hiroaki Yamato, Rehab Alshargabi, Takanori Shinjo, Yuki Nakao, Yukari Watanabe, Chikako Hayashi, Takaharu Taketomi, Takao Fukuda, Fusanori Nishimura Amelogenin Downregulates Interferon Gamma-Induced Major Histocompatibility Complex Class II Expression Through Suppression of Euchromatin Formation in the Class II Transactivator Promoter IV Region in Macrophages Front Immunol 2020 11:709 PubMed ID: 32373130 DOI: 10.3389/fimmu.2020.00709

10952 Seiichi Sato, Kai Li, Nozomi Sakurai, Mei Hashizume, Sunanda Baidya, Hirotaka Nonaka, Koki Noguchi, Kozo Ishikawa, Chikashi Obuse, Akinori Takaoka Regulation of an adaptor protein STING by Hsp90β to enhance innate immune responses against microbial infections Cell Immunol 2020 356:104188 PubMed ID: 32763501 DOI: 10.1016/j.cellimm.2020.104188

12599 Kobayashi N, Oda T, Takizawa M, Ishizaki T, Tsukamoto N, Yokohama A, Takei H, Saitoh T, Shimizu H, Honma K, Kimura-Masuda K, Kuroda Y, Ishihara R, Murakami Y, Murakami H, Handa H. Integrin α7 and Extracellular Matrix Laminin 211 Interaction Promotes Proliferation of Acute Myeloid Leukemia Cells and Is Associated with Granulocytic Sarcoma Cancers (Basel) 2020 12(2):363 PubMed ID: 32033262 DOI: 10.3390/cancers12020363

13083 Matsushita M, Nakamura T, Moriizumi H, Miki H, Takekawa M. Stress-responsive MTK1 SAPKKK serves as a redox sensor that mediates delayed and sustained activation of SAPKs by oxidative stress. Sci Adv 2020 PubMed ID: 32637591 DOI: 10.1126/sciadv.aay9778

13133 Tabata A, Ohkuni H, Hino H, Saigo T, Kodama C, Tang Q, Tomoyasu T, Fukunaga Y, Itoh Y, Nagamune H. Cytotoxic property of Streptococcus mitis strain producing two different types of cholesterol-dependent cytolysins. Infect Genet Evol 2020 PubMed ID: 32731044 DOI: 10.1016/j.meegid.2020.104483

13143 Akamatsu M, Mashiba R, Kawakatsu K, Ishikawa M, Nishikata T. Comparison of Macrophage Activation Using γ-Globulin and Serum-derived Macrophage Activating Factor. Anticancer Res 2020 PubMed ID: 32727796 DOI: 10.21873/anticanres.14471

13307 Yanaizu M, Washizu C, Nukina N, Satoh JI, Kino Y. CELF2 regulates the species-specific alternative splicing of TREM2. Sci Rep 2020 PubMed ID: 33093587 DOI: 10.1038/s41598-020-75057-x

13354 Noura M, Morita K, Kiyose H, Matsuo H, Nishinaka-Arai Y, Kurokawa M, Kamikubo Y, Adachi S. Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells. Sci Rep 2020 PubMed ID: 33219287 DOI: 10.1038/s41598-020-76951-0

13456 Hideo Kataoka, Ayumi Saeki, Akira Hasebe, Ken-ichiro Shibata, Takeshi Into Naringenin suppresses Toll-like receptor 2-mediated inflammatory responses through inhibition of receptor clustering on lipid rafts Food Sci Nutr 2020 PubMed ID: 33598179 DOI: 10.1002/fsn3.2063

4052 Kidoya H, Muramatsu F, Shimamura T, Jia W, Satoh T, Hayashi Y, Naito H, Kunisaki Y, Arai F, Seki M, Suzuki Y, Osawa T, Akira S, Takakura N. Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis Nat Commun 2019 10:1072 PubMed ID: 30842549 DOI: 10.1038/s41467-019-09028-w

11472 Suzuki S, Fukuda T, Nagayasu S, Nakanishi J, Yoshida K, Hirata-Tsuchiya S, Nakao Y, Sano T, Yamashita A, Yamada S, Ohta K, Shiba H, Nishimura F. Dental pulp cell-derived powerful inducer of TNF-α comprises PKR containing stress granule rich microvesicles. Sci Rep 2019 PubMed ID: 30846715 DOI: 10.1038/s41598-019-40046-2

6911 Tabata A, Yamada T, Ohtani H, Ohkura K, Tomoyasu T, Nagamune H. β-Hemolytic Streptococcus anginosus subsp. anginosus causes streptolysin S-dependent cytotoxicity to human cell culture lines in vitro. J Oral Microbiol 2019 11(1):1609839. PubMed ID: 31105901 DOI: 10.1080/20002297.2019.1609839

6929 Minato KI, Laan LC, van Die I, Mizuno M. Pleurotus citrinopileatus polysaccharide stimulates anti-inflammatory properties during monocyte-to-macrophage differentiation. Int J Biol Macromol 2019 122:705-712 PubMed ID: 30392853 DOI: 10.1016/j.ijbiomac.2018.10.157

6943 Yamamoto M, Matsumura R, Hirata Y, Nagamune H. A comparative study of skin irritation caused by novel bis-quaternary ammonium compounds and commonly used antiseptics by using cell culture methods. Toxicol In Vitro 2019 54:75-81 PubMed ID: 30240708 DOI: 10.1016/j.tiv.2018.09.009

10946 Tsubasa Koga, Keiko Morotomi-Yano, Takashi Sakugawa, Hisato Saitoh, Ken-Ichi Yano Nanosecond pulsed electric fields induce extracellular release of chromosomal DNA and histone citrullination in neutrophil-differentiated HL-60 cells Sci Rep 2019 9(1):8451 PubMed ID: 31186478 DOI: 10.1038/s41598-019-44817-9

12329 Iwashima T, Kudome Y, Kishimoto Y, Saita E, Tanaka M, Taguchi C, Hirakawa S, Mitani N, Kondo K, Iida K. Aronia berry extract inhibits TNF-α-induced vascular endothelial inflammation through the regulation of STAT3 Food Nutr Res 2019 16;63 PubMed ID: 31452653 DOI: 10.29219/fnr.v63.3361

12559 Li F, Kitajima S, Kohno S, Yoshida A, Tange S, Sasaki S, Okada N, Nishimoto Y, Muranaka H, Nagatani N, Suzuki M, Masuda S, Thai TC, Nishiuchi T, Tanaka T, Barbie DA, Mukaida N, Takahashi C. Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion Cancer Res 2019 79(15):3903-3915 PubMed ID: 31189648 DOI: 10.1158/0008-5472.CAN-18-3604

12597 Horiguchi Y, Ohta N, Yamamoto S, Koide M, Fujino Y. Midazolam suppresses the lipopolysaccharide-stimulated immune responses of human macrophages via translocator protein signaling Int Immunopharmacol 2019 66:373-382. PubMed ID: 30530051 DOI: 10.1016/j.intimp.2018.11.050

12600 Giriwono PE, Shirakawa H, Ohsaki Y, Sato S, Aoyama Y, Ho HJ, Goto T, Komai M. Geranylgeraniol Suppresses the Expression of IRAK1 and TRAF6 to Inhibit NFκB Activation in Lipopolysaccharide-Induced Inflammatory Responses in Human Macrophage-Like Cells Int J Mol Sci 2019 20(9):2320 PubMed ID: 31083375 DOI: 10.3390/ijms20092320

10592 Yamazoe H. Multifunctional protein microparticles for medical applications. Biomaterials 2018 155:1-12 PubMed ID: 29154040 DOI: 10.1016/j.biomaterials.2017.10.045

11096 Sumide K, Matsuoka Y, Kawamura H, Nakatsuka R, Fujioka T, Asano H, Takihara Y, Sonoda Y. A revised road map for the commitment of human cord blood CD34-negative hematopoietic stem cells. Nat Commun 2018 9(1):2202 PubMed ID: 29875383 DOI: 10.1038/s41467-018-04441-z

11176 Watanabe K, Suzuki H, Nishida T, Mishima M, Tachibana M, Fujishima M, Shimizu T, Watarai M. Identification of novel Legionella genes required for endosymbiosis in Paramecium based on comparative genome analysis with Holospora spp. FEMS Microbiol. Ecol. 2018 94(11) PubMed ID: 30124811 DOI: 10.1093/femsec/fiy162

11247 Zhitnyuk Y, Gee P, Lung MSY, Sasakawa N, Xu H, Saito H, Hotta A. Efficient mRNA delivery system utilizing chimeric VSVG-L7Ae virus-like particles. Biochem. Biophys. Res. Commun. 2018 PubMed ID: 30316514 DOI: 10.1016/j.bbrc.2018.09.113

11288 Segawa S, Kondo Y, Nakai Y, Iizuka A, Kaneko S, Yokosawa M, Furuyama K, Tsuboi H, Goto D, Matsumoto I, Sumida T. Placenta Specific 8 Suppresses IL-18 Production through Regulation of Autophagy and Is Associated with Adult Still Disease. J. Immunol. 2018 PubMed ID: 30404814 DOI: 10.4049/jimmunol.1800667

4362 Nagai K, Domon H, Maekawa T, Oda M, Hiyoshi T, Tamura H, Yonezawa D, Arai Y, Yokoji M, Tabeta K, Habuka R, Saitoh A, Yamaguchi M, Kawabata S, Terao Y. Pneumococcal DNA-binding proteins released through autolysis induce the production of proinflammatory cytokines via toll-like receptor 4. Cell. Immunol. 2018 325:14-22 PubMed ID: 29366563 DOI: 10.1016/j.cellimm.2018.01.006

4363 Yoshino H, Konno H, Ogura K, Sato Y, Kashiwakura I. Relationship between the Regulation of Caspase-8-Mediated Apoptosis and Radioresistance in Human THP-1-Derived Macrophages. Int J Mol Sci 2018 PubMed ID: 30322167 DOI: 10.3390/ijms19103154

4364 Mashiba R, Ishikawa M, Sumiya YU, Kawakatsu K, Tran NK, Nishikata T. Phagocytic Activation of Macrophages with Serum MAF Depends on Engulfment Efficiency and Not Migratory Activity. Anticancer Res. 2018 38(7):4295-4298 PubMed ID: 29970564 DOI: 10.21873/anticanres.12727

4365 Fukatsu H, Koide N, Tada-Oikawa S, Izuoka K, Ikegami A, Ichihara S, Ukaji T, Morita N, Naiki Y, Komatsu T, Umezawa K. NF‑κB inhibitor DHMEQ inhibits titanium dioxide nanoparticle‑induced interleukin‑1β production: Inhibition of the PM2.5‑induced inflammation model. Mol Med Rep 2018 18(6):5279-5285 PubMed ID: 30320338 DOI: 10.3892/mmr.2018.9533

4366 Komoda H, Shiraki A, Oyama JI, Nishikido T, Node K. Azelnidipine Inhibits the Differentiation and Activation of THP-1 Macrophages through the L-Type Calcium Channel. J. Atheroscler. Thromb. 2018 25(8):690-69 PubMed ID: 29398679 DOI: 10.5551/jat.41798

4506 Ebe H, Matsumoto I, Kawaguchi H, Kurata I, Tanaka Y, Inoue A, Kondo Y, Tsuboi H, Sumida T. Clinical and functional significance of STEAP4-splice variant in CD14⁺ monocytes in patients with rheumatoid arthritis. Clin. Exp. Immunol. 2018 191(3):338-348 PubMed ID: 29080328 DOI: 10.1111/cei.13076

4507 Yoshida K, Nakashima A, Doi S, Ueno T, Okubo T, Kawano KI, Kanawa M, Kato Y, Higashi Y, Masaki T. Serum-Free Medium Enhances the Immunosuppressive and Antifibrotic Abilities of Mesenchymal Stem Cells Utilized in Experimental Renal Fibrosis. Stem Cells Transl Med 2018 7(12):893-905 PubMed ID: 30269426 DOI: 10.1002/sctm.17-0284

10181 Yoshino H, Kumai Y, Kashiwakura I. Effects of endoplasmic reticulum stress on apoptosis induction in radioresistant macrophages. Mol Med Rep 2017 15:2867-2872 PubMed ID: 28447729 DOI: 10.3892/mmr.2017.6298

4520 Ken-ichiro Minato, Akihiro Ohara, and Masashi Mizuno A Proinflammatory Effect of the β-Glucan from Pleurotus cornucopiae Mushroom on Macrophage Action Mediators of Inflammation 2017 9 PubMed ID: 28611507 DOI: 10.1155/2017/8402405

4546 Arasaki K, Mikami Y, Shames SR, Inoue H, Wakana Y, Tagaya M. Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17. Nat Commun 2017 8:15406 PubMed ID: 28504273 DOI: 10.1038/ncomms15406

10964 Masataka Oda, Hisanori Domon, Mie Kurosawa, Toshihito Isono, Tomoki Maekawa, Masaya Yamaguchi, Shigetada Kawabata, Yutaka Terao Streptococcus pyogenes Phospholipase A 2 Induces the Expression of Adhesion Molecules on Human Umbilical Vein Endothelial Cells and Aorta of Mice Front Cell Infect Microbiol 2017 7:300 PubMed ID: 28713783 DOI: 10.3389/fcimb.2017.00300

14596 Yoshino H, Kashiwakura I. Involvement of reactive oxygen species in ionizing radiation-induced upregulation of cell surface Toll-like receptor 2 and 4 expression in human monocytic cells J Radiat Res 2017 58(5):626-635 PubMed ID: 28369600 DOI: 10.1093/jrr/rrx011

14666 Tabei Y, Sugino S, Eguchi K, Tajika M, Abe H, Nakajima Y, Horie M. Effect of calcium carbonate particle shape on phagocytosis and pro-inflammatory response in differentiated THP-1 macrophages Biochem Biophys Res Commun 2017 490(2):499-505 PubMed ID: 28624457 DOI: 10.1016/j.bbrc.2017.06.069

14711 Hojo K, Tamai R, Kobayashi-Sakamoto M, Kiyoura Y. Etidronate down-regulates Toll-like receptor (TLR) 2 ligand-induced proinflammatory cytokine production by inhibiting NF-κB activation Pharmacol Rep 2017 69(4):773-778 PubMed ID: 28587938 DOI: 10.1016/j.pharep.2017.03.009

7107 Yamazoe H, Ichikawa T, Hagihara Y, Iwasaki Y. Generation of a patterned co-culture system composed of adherent cells and immobilized nonadherent cells. Acta Biomater 2016 31:231-240 PubMed ID: 26685756 DOI: 10.1016/j.actbio.2015.12.016

9865 Seike S, Takehara M, Kobayashi K, Nagahama M. Role of pannexin 1 in Clostridium perfringens beta-toxin-caused cell death. Biochim. Biophys. Acta 2016 1858:3150-3156 PubMed ID: 27720686 DOI: 10.1016/j.bbamem.2016.10.003

9972 Uchida H, Hasegawa Y, Takahashi H, Makishima M. 1α-Dihydroxyvitamin D3 and Retinoic Acid Increase Nuclear Vitamin D Receptor Expression in Monocytic THP-1 Cells. Anticancer Res. 2016 36:6297-6301 PubMed ID: 27919949 DOI: 10.21873/anticanres.11225

12919 Deo VK, Kato T, Park EY. Virus-Like Particles Displaying Recombinant Short-Chain Fragment Region and Interleukin 2 for Targeting Colon Cancer Tumors and Attracting Macrophages J Pharm Sci 2016 105(5):1614-1622 PubMed ID: 27037014 DOI: 10.1016/j.xphs.2016.02.011

12957 Kameoka S, Kameyama T, Hayashi T, Sato S, Ohnishi N, Hayashi T, Murata-Kamiya N, Higashi H, Hatakeyama M, Takaoka A. Helicobacter pylori induces IL-1β protein through the inflammasome activation in differentiated macrophagic cells Biomed Res 2016 37(1):21-7. PubMed ID: 26912137 DOI: 10.2220/biomedres.37.21

13972 Tanaka M, Kishimoto Y, Saita E, Suzuki-Sugihara N, Kamiya T, Taguchi C, Iida K, Kondo K. Terminalia bellirica Extract Inhibits Low-Density Lipoprotein Oxidation and Macrophage Inflammatory Response in Vitro Antioxidants (Basel) 2016 5(2):20 PubMed ID: 27314393 DOI: 10.3390/antiox5020020

14035 Sumiya YU, Inoue T, Ishikawa M, Inui T, Kuchiike D, Kubo K, Uto Y, Nishikata T. Macrophages Exhibit a Large Repertoire of Activation States via Multiple Mechanisms of Macrophage-activating Factors Anticancer Res 2016 36(7):3619-23. PubMed ID: 27354632

7231 Yoshida K, Maekawa T, Zhu Y, Renard-Guillet C, Chatton B, Inoue K, Uchiyama T, Ishibashi K, Yamada T, Ohno N, Shirahige K, Okada-Hatakeyama M, Ishii S. The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory. Nat. Immunol. 2015 16:1034-43 PubMed ID: 26322480 DOI: 10.1038/ni.3257

7239 Nagahama M, Seike S, Shirai H, Takagishi T, Kobayashi K, Takehara M, Sakurai J. Role of P2X7 receptor in Clostridium perfringens beta-toxin-mediated cellular injury. Biochim. Biophys. Acta 2015 1850:2159-67 PubMed ID: 26299247 DOI: 10.1016/j.bbagen.2015.08.011

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