Cell No. : Cell Name
RCB1184 : Lu-165
update : 2021/02/26
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| Comment | Producing high level of anti-diuretic hormone. Application consideration |
| Comment from the depositor | |
| Terms and conditions | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
| Remarks | |
| Order Form |
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
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Basic information
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Depositor |
Terasaki, Takeo
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| Originator |
Terasaki, Takeo
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| Year of deposit |
1995
|
| Animal |
human
< Mammals
|
| Genus |
Homo
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| Species |
sapiens
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| Race |
Japanese
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| Gender |
Male
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| Age at sampling |
50 years
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| Tissue |
lung, lymph node meta
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| Disease name |
small cell carcinoma
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| Metastastatic ability |
Yes
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| Metastatsd tissue |
lymph node
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| Classification |
cancer
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| Year of origin |
1991
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|
Lifespan |
infinite
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| Morphology |
other
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| |
deposit info |
lot info |
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Medium |
Medium List |
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Culture type |
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Suspension cells
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| Medium and additives |
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RPMI1640 + 10% FBS
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| Antibiotics |
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Free
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Passage method |
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dilution
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Culture information
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Passage ratio |
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1 : 4 split
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| SC frequency |
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Subculture : once/week, Medium Renewal : 2 times/week
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| Temperature |
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37
℃
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| CO2 concentration |
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5
%
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| Freeze medium |
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Medium + 10% DMSO
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| Freezing method |
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Slow freezing
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| Mycoplasma |
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(-)
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| STR(human) |
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OK
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| Virus (HIV) |
|
(-)
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| Isozyme |
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LD, NP
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| Chromosome mode |
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37-107(50) : /39(1),40(6),41(17),42(13),43(6)/
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| Images |
deposit info | lot info |
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| Reference information |
Reference |
5
|
| User's Publication |
6
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| Reference |
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3152
Coulson, J M, Stanley J, Woll, P J
Tumour-specific arginine vasopressin promoter activation in small-cell lung cancer.
Br J Cancer
1999
80:1935-44
PubMed ID: 10471042
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3154
Coulson, J M, Fiskerstrand, C E, Woll, P J, Quinn, J P
Arginine vasopressin promoter regulation is mediated by a neuron-restrictive silencer element in small cell lung cancer.
Cancer Res
1999
59:5123-7
PubMed ID: 10537286
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3153
Coulson, J M, Fiskerstrand, C E, Woll, P J, Quinn, J P
E-box motifs within the human vasopressin gene promoter contribute to a major enhancer in small-cell lung cancer
Biochem J
1999
344:961-970
PubMed ID: 10585887
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3150
Tanaka K, Terasaki T
Development and elongation of neurite-like outgrowth on small cell lung cancer cell lines
Oncogene
1997
88:176-183
PubMed ID: 9119746
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1974
Terasaki T, Matsuno Y, Shimosato Y, Yamaguchi K, Ichinose H, Nagatsu T, Kato K
Establishment of a human small cell lung cancer cell line producing a large amount of anti-diuretic hormone.
Jpn J Cancer Res (--> Cancer Sci)
1994
85:718-22
PubMed ID: 8071114
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| User's Publication |
|
9502
Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N.
PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.
Cancer Cell
2018
33:355-367.e7
PubMed ID: 29533781
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12940
Ohta T, Mita M, Hishinuma S, Ishii-Nozawa R, Takahashi K, Shoji M.
Inhibition of Ectopic Arginine Vasopressin Production by Phenytoin in the Small Cell Lung Cancer Cell Line Lu-165
Front Endocrinol (Lausanne)
2017
8:94
PubMed ID: 28503166
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9873
Kato F, Fiorentino FP, Alibés A, Perucho M, Sánchez-Céspedes M, Kohno T, Yokota J.
MYCL is a target of a BET bromodomain inhibitor, JQ1, on growth suppression efficacy in small cell lung cancer cells.
Oncotarget
2016
7:77378-77388
PubMed ID: 27764802
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6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
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2929
Jones MH, Virtanen C, Honjoh D, Miyoshi T, Satoh Y, Okumura S, Nakagawa K, Nomura H, Ishikawa Y
Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small-cell and large-cell neuroendocrine carcinomas identified by gene expression profiles
Lancet
2004
63:775-781
PubMed ID: 15016488
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3338
Seike, Masahiro, Kondo, Tadashi, Fujii, Kazuyasu, Yamada, Tesshi, Gemma, Akihiko, Kudoh, Shoji, Hirohashi, Setsuo
Proteomic signature of human cancer cells.
Proteomics
2004
4:2776-88
PubMed ID: 15352251
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