細胞番号 : 細胞名
RCB1166 : KG-1
update : 2024/10/23
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細胞特性(Comment:英) | Human acute myeloid leukemia. The variant subline (RCB1928 KG-1a) CD3-,CD13+,CD14-,CD15+,CD19-,CD33+. Since “Terms and conditions” etc. for this cell line can be changed, the users of this cell line must refer to ACC 14 prior to order. |
細胞特性(日) | ヒト急性ミエロイド白血病株。独DSMZとの交換株。使用条件等が DSMZによって随時変更となる可能性があります。ご購入前に、ACC 14 を必ずご参照ください。 |
細胞特性(寄託者記述:英) | |
細胞特性(寄託者記述:日) | |
使用条件(英) | 1) There is no restriction regarding use for basic researches. However, since “Terms and conditions” etc. for this cell line can be changed, the users of this cell line must refer to ACC 14 prior to order. 2) In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
使用条件(日) | 1) 基礎的研究につきましては、使用制限はありません。しかし、使用条件等がDSMZによって随時変更となる可能性があるので、購入前に、ACC 14を必ず参照すること。2) 商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。 |
備考(英) | |
備考(日) | |
提供申込書類(英) |
Order Form(C-0005.pdf)
 
MTA(C-0007.pdf)
 
MTA(C-0007p.pdf)
 
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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提供申込書類(日) |
依頼書C-0001.pdf
 
同意書(非営利学術目的)C-0003.pdf
 
同意書(営利目的)C-0003p.pdf
 
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提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
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提供手数料 |
手数料とお支払いについてはこちらをご覧ください。 |
細胞基本情報
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寄託者 |
DSMZ
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寄託日 |
1995
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動物種 |
_human
< Mammals
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属名 |
Homo
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種名 |
sapiens
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性別 |
Male
|
齢 |
59 years
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採取組織 |
bone marrow
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病名 |
acute myeloid leukemia
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細胞分類 |
cancer
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入手歴 |
DSMZ (ACC14)
|
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細胞寿命 |
infinite
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細胞形態 |
lymphocyte-like
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Cellosaurus(Expasy) |
CVCL_0374
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細胞培養・検査情報
| |
寄託時情報 |
ロット情報 |
培地・試薬情報 |
培地・試薬一覧はこちらをご覧ください。 |
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培養形態 |
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Suspension cells
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培養方法 |
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General Guidelines for Culturing Suspension Cells, 浮遊細胞の培養に関する一般的な注意(Japanese)
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培地 |
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RPMI1640 + 10% FBS
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抗生物質 |
|
Free
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継代方法 |
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dilution
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継代密度 |
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1 : 10 split
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継代・培地交換頻度 |
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Subculture : 2 times/week
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培養最適温度 |
|
37
℃
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二酸化炭素濃度 |
|
5
%
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凍結培地 |
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Medium + 10% DMSO
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凍結方法 |
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Slow freezing
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マイコプラズマ/アコレプラズマ |
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(-)
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ウィルス(HIV) |
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LT 400
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ウィルス(HTLV-1) |
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(-)
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アイソザイム検査 |
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LD, NP
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染色体検査 |
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25-119(50) : /41(2),43(7),44(3),45(3),46(6),47(1)/
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個体識別検査 |
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OK
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画像情報 |
寄託時情報 | ロット情報 |
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文献情報 |
Reference(英) |
4件
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Reference(日) |
0件
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利用者成果(英) |
21件
|
利用者成果(日) |
0件
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利用者成果(英) |
21628
Kawakatsu R, Tadagaki K, Yamasaki K, Yoshida T.
Venetoclax efficacy on acute myeloid leukemia is enhanced by the combination with butyrate.
Sci Rep
2024
14(1):4975
PubMed ID: 38424468
DOI: 10.1038/s41598-024-55286-0
|
20451
Phan TKT, Do TL, Tachibana K, Kihara T.
Alpha-mangostin dephosphorylates ERM to induce adhesion and decrease surface stiffness in KG-1 cells.
Hum Cell
2022
PubMed ID: 34817798
DOI: 10.1007/s13577-021-00651-8
|
22284
Yoshida T, Yamasaki K, Tadagaki K, Kuwahara Y, Matsumoto A, Sofovic AE, Kondo N, Sakai T, Okuda T.
Tumor necrosis factor‑related apoptosis‑inducing ligand is a novel transcriptional target of runt‑related transcription factor 1
Int J Oncol
2022
60(1):6
PubMed ID: 34958111
DOI: 10.3892/ijo.2021.5296
|
16047
Kihara T, Matsumoto T, Nakahashi Y, Tachibana K.
Mechanical stiffness softening and cell adhesion are coordinately regulated by ERM dephosphorylation in KG-1 cells
Hum Cell
2021
34(6):1709-1716
PubMed ID: 34312810
DOI: 10.1007/s13577-021-00584-2
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11953
Tachibana K, Ohnishi H, Ali Haghparast SM, Kihara T, Miyake J.
Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31843195
DOI: 10.1016/j.bbrc.2019.12.044
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14832
Saito S, Kitamura-Muramatsu Y, Komine F, Polat M, Takeshima SN, Takei M, Aida Y.
Absence of bovine leukemia virus proviral DNA in Japanese human blood cell lines and human cancer cell lines
Arch Virol
2020
165(1):207-214
PubMed ID: 31776677
DOI: 10.1007/s00705-019-04474-9
|
11360
Futami K, Kimoto M, Lim YWS, Hirao I.
Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-Base DNA Aptamers Targeting Cancer Cells.
Mol Ther Nucleic Acids
2019
PubMed ID: 30594072
DOI: 10.1016/j.omtn.2018.11.011
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12516
Ono M, Takimoto R, Osuga T, Okagawa Y, Hirakawa M, Yoshida M, Arihara Y, Uemura N, Hayasaka N, Miura S, Matsuno T, Tamura F, Sato Y, Sato T, Iyama S, Miyanishi K, Takada K, Kobune M, Kato J.
Targeting Notch-1 positive acute leukemia cells by novel fucose-bound liposomes carrying daunorubicin
Oncotarget
2016
7(25):38586-38597
PubMed ID: 27233074
DOI: 10.18632/oncotarget.9558
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16179
Koya J, Kataoka K, Sato T, Bando M, Kato Y, Tsuruta-Kishino T, Kobayashi H, Narukawa K, Miyoshi H, Shirahige K, Kurokawa M.
DNMT3A R882 mutants interact with polycomb proteins to block haematopoietic stem and leukaemic cell differentiation
Nat Commun
2016
7:1092
PubMed ID: 27010239
DOI: 10.1038/ncomms10924
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19156
Miyuki Kumano-Kuramochi
Lectin-Like Oxidized LDL Receptor 1 Mediates the Uptake of the C-Terminal Domain of Hsp70 (A Promising Immune Adjuvant Molecule) and Antigen Peptide Complexes
International Journal of Biochemistry Research & Review
2014
4:284-294
DOI: 10.9734/ijbcrr/2014/8699
|
6082
Ohnishi H, Sasaki H, Nakamura Y, Kato S, Ando K, Narimatsu H, Tachibana K.
Regulation of cell shape and adhesion by CD34
Cell Adh Migr
2013
7(5):426-33
PubMed ID: 24036614
DOI: 10.4161/cam.25957
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15792
Kon A, Shih LY, Minamino M, Sanada M, Shiraishi Y, Nagata Y, Yoshida K, Okuno Y, Bando M, Nakato R, Ishikawa S, Sato-Otsubo A, Nagae G, Nishimoto A, Haferlach C, Nowak D, Sato Y, Alpermann T, Nagasaki M, Shimamura T, Tanaka H, Chiba K, Yamamoto R, Yamaguchi T, Otsu M, Obara N, Sakata-Yanagimoto M, Nakamaki T, Ishiyama K, Nolte F, Hofmann WK, Miyawaki S, Chiba S, Mori H, Nakauchi H, Koeffler HP, Aburatani H, Haferlach T, Shirahige K, Miyano S, Ogawa S.
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms
Nat Genet
2013
45(10):1232-7
PubMed ID: 23955599
DOI: 10.1038/ng.2731
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7886
Saito Y, Nakahata S, Yamakawa N, Kaneda K, Ichihara E, Suekane A, Morishita K.
CD52 as a molecular target for immunotherapy to treat acute myeloid leukemia with high EVI1 expression.
Leukemia
2011
25:921-31
PubMed ID: 21394097
DOI: 10.1038/leu.2011.36
|
8778
Keiko Fukushima and Katsuko Yamashita
Carbohydrate Recognition by Cytokines and Its Relevance to Their Physiological Activities
Experimental Glycoscience
2008
154-157
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5983
Nemoto N, Suzukawa K, Shimizu S, Shinagawa A, Takei N, Taki T, Hayashi Y, Kojima H, Kawakami Y, Nagasawa T.
Identification of a novel fusion gene MLL-MAML2 in secondary acute myelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23).
Genes Chromosomes Cancer
2007
46(9):813-9
PubMed ID: 17551948
DOI: 10.1002/gcc.20467
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6144
Ninomiya M, Abe A, Katsumi A, Xu J, Ito M, Arai F, Suda T, Ito M, Kiyoi H, Kinoshita T, Naoe T.
Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice.
Leukemia
2007
21(1):136-42
PubMed ID: 17039228
DOI: 10.1038/sj.leu.2404432
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8818
Matsumoto E, Hatanaka M, Bohgaki M, Maeda S.
PKC pathway and ERK/MAPK pathway are required for induction of cyclin D1 and p21Waf1 during 12-o-tetradecanoylphorbol 13-acetate-induced differentiation of myeloleukemia cells.
Kobe J Med Sci
2006
52:181-94
PubMed ID: 17329956
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3335
Yoshino K, Iimura E, Saijo K, Iwase S, Fukami K, Ohno T, Obata Y, Nakamura Y.
Essential role for gene profiling analysis in the authentication of human cell lines.
Hum Cell
2006
19(1):43-8
PubMed ID: 16643607
DOI: 10.1111/j.1749-0774.2005.00007.x
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2974
Tamura H, Dan K, Tamada K, Nakamura K, Shioi Y, Hyodo H, Wang SD, Dong H, Chen L, Ogata K
Expression of functional B7-H2 and B7.2 costimulatory molecules and their prognostic implications in de novo acute myeloid leukemia
Clin Cancer Res
2005
15:5708-5717
PubMed ID: 16115907
DOI: 10.1158/1078-0432.CCR-04-2672
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2913
Fukushima K, Ikehara Y, Yamashita K
Functional role played by the glycosylphosphatidylinositol anchor glycan of CD48 in interleukin-18-induced interferon-gamma production.
J Biol Chem
2005
280:18056-62
PubMed ID: 15760905
DOI: 10.1074/jbc.M413297200
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5943
Rumi MA, Sato H, Ishihara S, Ortega C, Kadowaki Y, Kinoshita Y.
Growth inhibition of esophageal squamous carcinoma cells by peroxisome proliferator-activated receptor-gamma ligands.
J Lab Clin Med
2002
140(1):17-26
PubMed ID: 12080324
DOI: 10.1067/mlc.2002.125055
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