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Cell No. : Cell Name
RCB1127 : MC3T3-G2/PA6  update : 2022/07/13
CommentSupport hematpoietic stem cell and osteoclast differentiation. Pre-adipocyte.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Kodama, Hiroaki
Originator Kodama, Hiroaki
Year of deposit 1994
Another name PA6
Original cell MC3T3-G2
Animal mouse < Mammals
Strain name C57BL/6
Gender Unknown
Age at sampling 0 day
Tissue newborn, calvaria
Classification other
Lifespan infinite
Morphology fibroblast-like
Cellosaurus(Expasy) CVCL_5441
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives MEM ALPHA + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : once/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
SSLP(mouse) OK
Isozyme LD, NP
deposit info
lot info
Reference information Reference 2
User's Publication 111

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1846  Kodama, H A, Amagai Y, Koyama H, Kasai S  Hormonal responsiveness of a preadipose cell line derived from newborn mouse calvaria.  J Cell Physiol  1982  112:83-8  PubMed ID: 7107717
1847  Kodama, H A, Amagai Y, Koyama H, Kasai S  A new preadipose cell line derived from newborn mouse calvaria can promote the proliferation of pluripotent hemopoietic stem cells in vitro.  J Cell Physiol  1982  112:89-95  PubMed ID: 7107718

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User's Publication
20326  Gualandris A, Noghero A, Cora' D, Astanina E, Arese M, Bussolino F.  Role of TGFβ1 and WNT6 in FGF2 and BMP4-driven endothelial differentiation of murine embryonic stem cells.  Angiogenesis  2022    PubMed ID: 34478025
20769  Yamazoe H, Kurinomaru T, Inagaki A.  Potential of the Coordinated Actions of Multiple Protein-Based Micromachines for Medical Applications.  ACS Appl Mater Interfaces  2022    PubMed ID: 35822220
20054  Tomita H, Tanaka K, Hirata A, Okada H, Imai H, Shirakami Y, Ohnishi K, Sugie S, Aoki H, Hatano Y, Noguchi K, Kanayama T, Niwa A, Suzui N, Miyazaki T, Tanaka T, Akiyama H, Shimizu M, Yoshida K, Hara A.  Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas.  Cell Rep  2021  34(8):108772  PubMed ID: 33626352
14070  Kondo T.  Selective eradication of pluripotent stem cells by inhibiting DHODH activity  Stem Cells  2021  39(1):33-42  PubMed ID: 33038285
14511  Wei M, Li S, Yang Z, Cheng C, Li T, Le W.  Tetrahedral DNA nanostructures functionalized by multivalent microRNA132 antisense oligonucleotides promote the differentiation of mouse embryonic stem cells into dopaminergic neurons  Nanomedicine  2021  34:102375  PubMed ID: 33617970
20508  Lee HS, Mok J, Joo CK.  Bone Morphogenetic Protein 4 (BMP4) Enhances the Differentiation of Human Induced Pluripotent Stem Cells into Limbal Progenitor Cells.  Curr Issues Mol Biol  2021  43(3):2124-2134  PubMed ID: 34940121
16763  Kitamura N, Fujiwara N, Hayakawa K, Ohama T, Sato K.  Protein phosphatase 6 promotes neurite outgrowth by promoting mTORC2 activity in N2a cells  J Biochem  2021  170(1):131-138  PubMed ID: 34314486
12175  Hiroki Masuda, Yoshinori Arisaka, Ruriko Sekiya-Aoyama, Tetsuya Yoda, Nobuhiko Yui   Biological Effects of Polyrotaxane Surfaces on Cellular Responses of Fibroblast, Preosteoblast and Preadipocyte Cell Lines  Polymers  2020    PubMed ID: 32316349
11367  Ishijima Y, Ohmori S, Uneme A, Aoki Y, Kobori M, Ohida T, Arai M, Hosaka M, Ohneda K.  The Gata2 repression during 3T3-L1 preadipocyte differentiation is dependent on a rapid decrease in histone acetylation in response to glucocorticoid receptor activation.  Mol. Cell. Endocrinol.  2019    PubMed ID: 30615908
11968  Hayakawa K, Nishitani K, Tanaka S.  Kynurenine, 3-OH-kynurenine, and anthranilate are nutrient metabolites that alter H3K4 trimethylation and H2AS40 O-GlcNAcylation at hypothalamus-related loci.  Sci Rep  2019    PubMed ID: 31875008
12480  Paerhati P, Ito A, Yoshioka K, Iwamoto K, Fujiwara S, Horie M, Kawabe Y, Kamihira M.  Neural differentiation of mouse induced pluripotent stem cells using cadherin gene-engineered PA6 feeder cells  J Biosci Bioeng  2019  127(5):633-640  PubMed ID: 30391238
10471  Nugroho AE, Hashimoto A, Wong CP, Yokoe H, Tsubuki M, Kaneda T, Hadi AHA, Morita H.  Ceramicines M-P from Chisocheton ceramicus: isolation and structure-activity relationship study.  J Nat Med  2018  72:64-72  PubMed ID: 28822030
4284  Carr-Wilkinson J, Prathalingam N, Pal D, Moad M, Lee N, Sundaresh A, Forgham H, James P, Herbert M, Lako M, Tweddle DA.  Differentiation of Human Embryonic Stem Cells to Sympathetic Neurons: A Potential Model for Understanding Neuroblastoma Pathogenesis.  Stem Cells Int  2018    PubMed ID: 30515222
4285  Méndez-Maldonado K, Vega-López G, Caballero-Chacón S, Aybar MJ, Velasco I.  Activation of Hes1 and Msx1 in Transgenic Mouse Embryonic Stem Cells Increases Differentiation into Neural Crest Derivatives.  Int J Mol Sci  2018    PubMed ID: 30551562
4492  Joshi R, Fuller B, Mosadegh B, Tavana H.  Stem cell colony interspacing effect on differentiation to neural cells.  J Tissue Eng Regen Med  2018  12(10):2041-2054  PubMed ID: 30058271
10340  Ogawa Y, Kaizu K, Yanagi Y, Takada S, Sakuraba H, Oishi K.  Abnormal differentiation of Sandhoff disease model mouse-derived multipotent stem cells toward a neural lineage.  PLoS ONE  2017  12:e0178978  PubMed ID: 28575132
5771  Hayakawa K, Sakamoto Y, Kanie O, Ohtake A, Daikoku S, Ito Y, Shiota K.  Reactivation of hyperglycemia-induced hypocretin (HCRT) gene silencing by N-acetyl-d-mannosamine in the orexin neurons derived from human iPS cells.  Epigenetics  2017  12(9):764-778  PubMed ID: 28762874
9457  Junho Kim, Chugmin Han, Wonju Jo, Sehong Kang, Siwoo Cho, Dayeong Jeong, Yong Song Gho, Jaesung Park  Cell-Engineered Nanovesicle as a Surrogate Inducer of Contact-Dependent Stimuli  Adv Healthc Mater  2017  6(17)  PubMed ID: 28643483
14048  Wei M, Li S, Yang Z, Zheng W, Le W.  Gold nanoparticles enhance the differentiation of embryonic stem cells into dopaminergic neurons via mTOR/p70S6K pathway  Nanomedicine (Lond)  2017  12(11):1305-1317  PubMed ID: 28520507
14569  Newman EA, Chukkapalli S, Bashllari D, Thomas TT, Van Noord RA, Lawlor ER, Hoenerhoff MJ, Opipari AW, Opipari VP.  Alternative NHEJ pathway proteins as components of MYCN oncogenic activity in human neural crest stem cell differentiation: implications for neuroblastoma initiation  Cell Death Dis  2017  8(12):3208  PubMed ID: 29238067
14723  Nakajima K, So M, Takahashi K, Tagawa YI, Hirao M, Goto Y, Ogi H.  Optimized Ultrasonic Irradiation Finds Out Ultrastable Aβ 1-40 Oligomers  J Phys Chem B  2017  121(12):2603-2613  PubMed ID: 28260388
14776  Joshi R, Buchanan JC, Tavana H.  Self-regulatory factors of embryonic stem cells in co-culture with stromal cells enhance neural differentiation  Integr Biol (Camb)  2017  9(5):418-426  PubMed ID: 28406502
10023  Gökcan MK, Mülazimoğlu S, Ocak E, Can P, Çalışkan M, Beşaltı Ö, Dizbay Sak S, Kaygusuz G.  Study of mouse induced pluripotent stem cell transplantation intoWistar albino rat cochleae after hair cell damage.  Turk J Med Sci  2016  46:1603-1610  PubMed ID: 27966334
6004  Hertsenberg AJ, Funderburgh JL.  Generation of Corneal Keratocytes from Human Embryonic Stem Cells.  Methods Mol Biol  2016  1341:285-94  PubMed ID: 26026882
9431  Anita Bonic, Mack Poon, Michael G Woods, Alan O Trounson  Expression of Neural Crest Markers by Human Embryonic Stem Cells: An Introductory Project  Aust Orthod J  2016  32(2):175-183.  PubMed ID: 29509342
12908  Zhang JT, Weng ZH, Tsang KS, Tsang LL, Chan HC, Jiang XH.  MycN Is Critical for the Maintenance of Human Embryonic Stem Cell-Derived Neural Crest Stem Cells  PLoS One  2016  11(1):e0148062  PubMed ID: 26815535
13952  Hedlund E, Belnoue L, Theofilopoulos S, Salto C, Bye C, Parish C, Deng Q, Kadkhodaei B, Ericson J, Arenas E, Perlmann T, Simon A.  Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors  Sci Rep  2016  6:26448  PubMed ID: 27246266
14037  Joshi R, Buchanan JC, Paruchuri S, Morris N, Tavana H.  Molecular Analysis of Stromal Cells-Induced Neural Differentiation of Mouse Embryonic Stem Cells  PLoS One  2016  11(11):e0166316  PubMed ID: 27832161
14038  Joshi R, Buchanan J, Tavana H.  Colony size effect on neural differentiation of embryonic stem cells microprinted on stromal cells  Annu Int Conf IEEE Eng Med Biol Soc  2016  4173-4176  PubMed ID: 28269202
7223  Arai Y, Hayakawa K, Arai D, Ito R, Iwasaki Y, Saito K, Akutsu K, Takatori S, Ishii R, Hayashi R, Izumi S, Sugino N, Kondo F, Horie M, Nakazawa H, Makino T, Hirosawa M, Shiota K, Ohgane J.  Putative Epimutagens in Maternal Peripheral and Cord Blood Samples Identified Using Human Induced Pluripotent Stem Cells.  Biomed Res Int  2015  2015:876047  PubMed ID: 26339649
9391  Hideki Sugimoto, Kiyoko Watanabe, Toshizo Toyama, Shun-suke Takahashi, Shuta Sugiyama, Masaichi-Chang-il Lee, Nobushiro Hamada  Inhibitory Effects of French Pine Bark Extract, Pycnogenol®, on Alveolar Bone Resorption and on the Osteoclast Differentiation  Phytother Res  2015  29(2):251-9  PubMed ID: 25336411
14984  Himeno T, Kamiya H, Naruse K, Cheng Z, Ito S, Shibata T, Kondo M, Kato J, Okawa T, Fujiya A, Suzuki H, Kito T, Hamada Y, Oiso Y, Isobe K, Nakamura J.  Angioblast Derived from ES Cells Construct Blood Vessels and Ameliorate Diabetic Polyneuropathy in Mice  J Diabetes Res  2015  2015:257230  PubMed ID: 25977928
15164  An in vitro model of latency and reactivation of varicella zoster virus in human stem cell-derived neurons  An in vitro model of latency and reactivation of varicella zoster virus in human stem cell-derived neurons  PLoS Pathog  2015  11(6):e1004885  PubMed ID: 26042814
15252  Joshi R, Tavana H.  Microengineered embryonic stem cells niche to induce neural differentiation  Annu Int Conf IEEE Eng Med Biol Soc  2015  2015:3557-60  PubMed ID: 26737061
9867  Takeda O, Toyama T, Watanabe K, Sato T, Sasaguri K, Akimoto S, Sato S, Kawata T, Hamada N.  Ameliorating effects of Juzentaihoto on restraint stress and P. gingivalis-induced alveolar bone loss.  Arch. Oral Biol.  2014  59:1130-8  PubMed ID: 25064760
5418  Wong CP, Kaneda T, Hadi AH, Morita H.  Ceramicine B, a limonoid with anti-lipid droplets accumulation activity from Chisocheton ceramicus.  J Nat Med  2014  68(1):22-30  PubMed ID: 23494817
9345  Sunao Takeshita, Toshio Fumoto, Yoshinori Naoe, Kyoji Ikeda  Age-related Marrow Adipogenesis Is Linked to Increased Expression of RANKL  J Biol Chem  2014  289(24):16699-710  PubMed ID: 24753250
17154  Yang D, Li T, Xu M, Gao F, Yang J, Yang Z, Le W.  Graphene oxide promotes the differentiation of mouse embryonic stem cells to dopamine neurons  Nanomedicine (Lond)  2014  9(16):2445-55  PubMed ID: 24564300
5998  Chan AA, Hertsenberg AJ, Funderburgh ML, Mann MM, Du Y, Davoli KA, Mich-Basso JD, Yang L, Funderburgh JL.  Differentiation of human embryonic stem cells into cells with corneal keratocyte phenotype.  PLoS One  2013  8(2):e56831  PubMed ID: 23437251
6173  Belinsky GS, Sirois CL, Rich MT, Short SM, Moore AR, Gilbert SE, Antic SD.  Dopamine receptors in human embryonic stem cell neurodifferentiation.  Stem Cells Dev  2013  22(10):1522-40  PubMed ID: 23286225
6208  Ogawa Y, Tanaka M, Tanabe M, Suzuki T, Togawa T, Fukushige T, Kanekura T, Sakuraba H, Oishi K.  Impaired neural differentiation of induced pluripotent stem cells generated from a mouse model of Sandhoff disease.  PLoS One  2013  8(1):e55856  PubMed ID: 23383290
15785  Chang DJ, Lee N, Park IH, Choi C, Jeon I, Kwon J, Oh SH, Shin DA, Do JT, Lee DR, Lee H, Moon H, Hong KS, Daley GQ, Song J.  Therapeutic potential of human induced pluripotent stem cells in experimental stroke  Cell Transplant  2013  22(8):1427-40  PubMed ID: 23044029
5993  enham M, Parish CL, Leaw B, Wright J, Reid CA, Petrou S, Dottori M, Thompson LH.  Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation.  Front Cell Neurosci  2012  6:11  PubMed ID: 22470319
9227  Toshizo Toyama, Kazuo Todoki, Yusuke Takahashi, Kiyoko Watanabe, Shun-suke Takahashi, Shuta Sugiyama, Masaichi-Chang-il Lee, Nobushiro Hamada  Inhibitory Effects of Jixueteng on P. Gingivalis-Induced Bone Loss and Osteoclast Differentiation  Arch Oral Biol  2012  57(11):1529-36  PubMed ID: 22749496
9238  Takenori Sato, Kiyoko Watanabe, Hidefumi Kumada, Toshizo Toyama, Nobuyuki Tani-Ishii, Nobushiro Hamada  Peptidoglycan of Actinomyces Naeslundii Induces Inflammatory Cytokine Production and Stimulates Osteoclastogenesis in Alveolar Bone Resorption  Arch Oral Biol  2012  57(11):1522-8  PubMed ID: 22939375
9248  Y Ouji, S Ishizaka, F Nakamura-Uchiyama, M Yoshikawa  In Vitro Differentiation of Mouse Embryonic Stem Cells Into Inner Ear Hair Cell-Like Cells Using Stromal Cell Conditioned Medium  Cell Death Dis  2012  3(5):e314  PubMed ID: 22622133
9249  Josema Torres, Javier Prieto, Fabrice C Durupt, Simon Broad, Fiona M Watt  Efficient Differentiation of Embryonic Stem Cells Into Mesodermal Precursors by BMP, Retinoic Acid and Notch Signalling  PLoS One  2012  7(4):e36405  PubMed ID: 22558462
9250  Takeshi Shimada, Yoshihiro Takai, Kikuko Shinohara, Atsushi Yamasaki, Keiko Tominaga-Yoshino, Akihiko Ogura, Akihiro Toi, Kouji Asano, Norihito Shintani, Atsuko Hayata-Takano, Akemichi Baba, Hitoshi Hashimoto  A Simplified Method to Generate Serotonergic Neurons From Mouse Embryonic Stem and Induced Pluripotent Stem Cells  J Neurochem  2012  122(1):81-93  PubMed ID: 22404309
15737  Yang D, Li T, Wang Y, Tang Y, Cui H, Tang Y, Zhang X, Chen D, Shen N, Le W.  miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression  J Cell Sci  2012  125(Pt 7):1673-82  PubMed ID: 22328530
15997  Nefzger CM, Su CT, Fabb SA, Hartley BJ, Beh SJ, Zeng WR, Haynes JM, Pouton CW.  Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cells  Stem Cells  2012  30(7):1349-61  PubMed ID: 22495882
7759  Liu CQ, Guo Y, Guan WJ, Ma YH.  Establishment and characterization of a fibroblast cell line derived from Mongolian sheep.  Anim. Sci. J.  2011  82:215-22  PubMed ID: 21729198
7841  Markus A, Grigoryan S, Sloutskin A, Yee MB, Zhu H, Yang IH, Thakor NV, Sarid R, Kinchington PR, Goldstein RS.  Varicella-zoster virus (VZV) infection of neurons derived from human embryonic stem cells: direct demonstration of axonal infection, transport of VZV, and productive neuronal infection.  J. Virol.  2011  85:6220-33  PubMed ID: 21525353
8061  Zhong B, Trobridge GD, Zhang X, Watts KL, Ramakrishnan A, Wohlfahrt M, Adair JE, Kiem HP.  Efficient generation of nonhuman primate induced pluripotent stem cells.  Stem Cells Dev.  2011  20:795-807  PubMed ID: 21058905
8065  Ziegler L, Grigoryan S, Yang IH, Thakor NV, Goldstein RS.  Efficient generation of schwann cells from human embryonic stem cell-derived neurospheres.  Stem Cell Rev  2011  7:394-403  PubMed ID: 21052870
8107  Kitajima S, Miki T, Takegami Y, Kido Y, Noda M, Hara E, Shamma A, Takahashi C.  Reversion-inducing cysteine-rich protein with Kazal motifs interferes with epidermal growth factor receptor signaling.  Oncogene  2011  30:737-50  PubMed ID: 20890302
8431  Mark Denham, Mirella Dottori  Neural Differentiation of Induced Pluripotent Stem Cells  Methods Mol Biol  2011  793:99-110  PubMed ID: 21913096
12232  Jae-Hyung Jang, James T Koerber, Jung-Suk Kim, Prashanth Asuri, Tandis Vazin, Melissa Bartel, Albert Keung, Inchan Kwon, Kook In Park, David V Schaffer  An evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cells  Mol Ther  2011  19(4):667-75  PubMed ID: 21224831
15630  Otani T, Tsuji-Takayama K, Okochi A, Yamamoto M, Takeuchi M, Yamasaki F, Nakamura S, Kibata M.  Stromal cells' B7-1 is a key stimulatory molecule for interleukin-10 production by HOZOT, a multifunctional regulatory T-cell line  Immunol Cell Biol  2011  89(2):246-54  PubMed ID: 20628373
8281  Fernando CV, Moses D, Parish CL, Tomas D, Drago J, Horne MK.  Creating a ventral midbrain stem cell niche in an animal model for Parkinson's disease.  Stem Cells Dev.  2010  19:1995-2007  PubMed ID: 20415529
8480  Ziegler L, Segal-Ruder Y, Coppola G, Reis A, Geschwind D, Fainzilber M, Goldstein RS.  A human neuron injury model for molecular studies of axonal regeneration.  Exp. Neurol.  2010  223:119-27  PubMed ID: 19804775
8521  Yamazoe H, Okuyama T, Suzuki H, Fukuda J.  Fabrication of patterned cell co-cultures on albumin-based substrate: applications for microfluidic devices.  Acta Biomater  2010  6:526-33  PubMed ID: 19654059
5779  Takenaka C, Nishishita N, Takada N, Jakt LM, Kawamata S.  Effective generation of iPS cells from CD34+ cord blood cells by inhibition of p53.  Exp Hematol  2010  38(2):154-62  PubMed ID: 19922768
5988  Oda Y, Yoshimura Y, Ohnishi H, Tadokoro M, Katsube Y, Sasao M, Kubo Y, Hattori K, Saito S, Horimoto K, Yuba S, Ohgushi H.  Induction of pluripotent stem cells from human third molar mesenchymal stromal cells.  J Biol Chem  2010  285(38):29270-8  PubMed ID: 20595386
15629  Goldstein RS, Pomp O, Brokhman I, Ziegler L.  Generation of neural crest cells and peripheral sensory neurons from human embryonic stem cells  Methods Mol Biol  2010  584:283-300  PubMed ID: 19907983
8527  Nishimura K, Nakagawa T, Ono K, Ogita H, Sakamoto T, Yamamoto N, Okita K, Yamanaka S, Ito J.  Transplantation of mouse induced pluripotent stem cells into the cochlea.  Neuroreport  2009  20:1250-4  PubMed ID: 19625987
5986  Jiang X, Gwye Y, McKeown SJ, Bronner-Fraser M, Lutzko C, Lawlor ER.  Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells.  Stem Cells Dev  2009  18(7):1059-70  PubMed ID: 19099373
5987  Fusaki N, Ban H, Nishiyama A, Saeki K, Hasegawa M.  Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome.  Proc Jpn Acad Ser B Phys Biol Sci  2009  85(8):348-62.  PubMed ID: 19838014
6134  Ban N, Kai M  Implication of replicative stress-related stem cell ageing in radiation-induced murine leukaemia.  Br J Cancer.   2009  101(2):363-71  PubMed ID: 19513063
6169  Vazin 1, Becker KG, Chen J, Spivak CE, Lupica CR, Zhang Y, Worden L, Freed WJ.  A novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cells.  PLoS One  2009  4(8):e6606  PubMed ID: 19672298
8033  Takahashi J, Takagi Y, Saiki H.  Transplantation of embryonic stem cell-derived dopaminergic neurons in MPTP-treated monkeys  Methods Mol Biol  2009  482:199-212  PubMed ID: 19089358
8719  Ogita H, Nakagawa T, Lee KY, Inaoka T, Okano T, Kikkawa YS, Sakamoto T, Ito J.  Surgical invasiveness of cell transplantation into the guinea pig cochlear modiolus.  ORL J. Otorhinolaryngol. Relat. Spec.  2008  71:32-9  PubMed ID: 18971600
8747  Matsumoto M, Nakagawa T, Kojima K, Sakamoto T, Fujiyama F, Ito J.  Potential of embryonic stem cell-derived neurons for synapse formation with auditory hair cells.  J. Neurosci. Res.  2008  86:3075-85  PubMed ID: 18543340
5984  Pomp O, Brokhman I, Ziegler L, Almog M, Korngreen A, Tavian M, Goldstein RS.  PA6-induced human embryonic stem cell-derived neurospheres: a new source of human peripheral sensory neurons and neural crest cells.  Brain Res  2008  1230:50-60  PubMed ID: 18671952
5985  Vazin T, Chen J, Lee CT, Amable R, Freed WJ.  Assessment of stromal-derived inducing activity in the generation of dopaminergic neurons from human embryonic stem cells.  Stem Cells  2008  26(6):1517-25  PubMed ID: 18388303
7645  Shimizu N, Noda S, Katayama K, Ichikawa H, Kodama H, Miyoshi H.  Identification of genes potentially involved in supporting hematopoietic stem cell activity of stromal cell line MC3T3-G2/PA6.  Int J Hematol  2008  87(3):239-45  PubMed ID: 18317883
7676  Yagi M, Suzuki N, Takayama T, Arisue M, Kodama T, Yoda Y, Numasaki H, Otsuka K, Ito K.  Lactoferrin suppress the adipogenic differentiation of MC3T3-G2/PA6 cells.  J Oral Sci  2008  50(4):419-25  PubMed ID: 19106469
9485  Tandis Vazin, Jia Chen, Charles E Spivak, Rose Amable, Emily Gabitzsch, Chun-Ting Lee, Carl R Lupica, William J Freed  Dopaminergic Neurons Derived From BG01V2, a Variant of Human Embryonic Stem Cell Line BG01  Restor Neurol Neurosci   2008  26(6):447-58  PubMed ID: 19096132
5975  Hedlund E, Pruszak J, Ferree A, Viñuela A, Hong S, Isacson O, Kim KS.  Selection of embryonic stem cell-derived enhanced green fluorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations.  Stem Cells  2007  25(5):1126-35  PubMed ID: 17234989
7353  Anisimov SV, Christophersen NS, Correia AS, Li JY, Brundin P.  "NeuroStem Chip": a novel highly specialized tool to study neural differentiation pathways in human stem cells.  BMC Genomics  2007  8:46  PubMed ID: 17288595
7354  Takahashi N, Udagawa N, Kobayashi Y, Suda T.  Generation of osteoclasts in vitro, and assay of osteoclast activity.  Methods Mol Med  2007  135:285-301  PubMed ID: 17951666
8942  Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka  Induction of Pluripotent Stem Cells From Adult Human Fibroblasts by Defined Factors  Cell  2007  131 (5), 861-72  PubMed ID: 18035408
3399  Moriyasu, Kenta, Yamazoe, Hironori, Iwata, Hiroo  Induction dopamine releasing cells from mouse embryonic stem cells and their long-term culture.  J Biomed Mater Res A  2006  77:136-47  PubMed ID: 16392122
8863  Sato N, Brivanlou AH.  Manipulation of self-renewal in human embryonic stem cells through a novel pharmacological GSK-3 inhibitor.  Methods Mol. Biol.  2006  331:115-28  PubMed ID: 16881513
8921  Sekiya T, Kojima K, Matsumoto M, Kim TS, Tamura T, Ito J.  Cell transplantation to the auditory nerve and cochlear duct.  Exp. Neurol.  2006  198:12-24  PubMed ID: 16376874
5974  Lin L1, Isacson O.  Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits.  Stem Cells  2006  24(11):2504-13  PubMed ID: 16840550
5981  Carpenter M, Rao MS, Freed W, Zeng X.  Derivation and characterization of neuronal precursors and dopaminergic neurons from human embryonic stem cells in vitro.  Methods Mol Biol  2006  331:153-67.  PubMed ID: 16881516
6149  Roybon L, Ma Z, Asztely F, Fosum A, Jacobsen SE, Brundin P, Li JY.  Failure of transdifferentiation of adult hematopoietic stem cells into neurons.  Stem Cells  2006  24(6):1594-604  PubMed ID: 16556707
2925  Thinyane K, Baier PC, Schindehutte J, Mansouri A, Paulus W, Trenkwalder C, Flugge G, Fuchs E  Fate of pre-differentiated mouse embryonic stem cells transplanted in unilaterally 6-hydroxydopamine lesioned rats: histological characterization of the grafted cells.  Brain Res  2005  1045:80-7  PubMed ID: 15910765
3373  Pomp, Oz, Brokhman, Irina, Ben-Dor, Israel, Reubinoff, Benjamin, Goldstein, Ronald S  Generation of peripheral sensory and sympathetic neurons and neural crest cells from human embryonic stem cells.  Stem Cells  2005  23:923-30  PubMed ID: 15883233
8938  Okano T, Nakagawa T, Endo T, Kim TS, Kita T, Tamura T, Matsumoto M, Ohno T, Sakamoto T, Iguchi F, Ito J.  Engraftment of embryonic stem cell-derived neurons into the cochlear modiolus.  Neuroreport  2005  16:1919-22  PubMed ID: 16272879
8972  Kim TS, Nakagawa T, Kita T, Higashi T, Takebayashi S, Matsumoto M, Kojima K, Sakamoto T, Ito J.  Neural connections between embryonic stem cell-derived neurons and vestibular hair cells in vitro.  Brain Res.  2005  1057:127-33  PubMed ID: 16122715
9025  Matsumoto M, Nakagawa T, Higashi T, Kim TS, Kojima K, Kita T, Sakamoto T, Ito J.  Innervation of stem cell-derived neurons into auditory epithelia of mice.  Neuroreport  2005  16:787-90  PubMed ID: 15891570
6828  Morito S, Yaguchi K, Imada M, Tachikawa C, Nomura M, Moritani S, Igarashi M, Yokogawa K, Miyamoto K.  Insulin signaling in adipocytes differentiated from mouse stromal MC3T3-G2/PA6 cells.  Biol Pharm Bull  2005  28(11):2040-5  PubMed ID: 16272686
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