CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [RCB1126 : MC3T3-E1]

1995 Zhou, H Y, Takita H, Fujisawa R, Mizuno M, Kuboki Y Stimulation by bone sialoprotein of calcification in osteoblast-like MC3T3-E1 cells. Calcif Tissue Int 1995 56:403-7 PubMed ID: 7621349 DOI: 10.1007/bf00301610

1993 Kobayashi T, Sugimoto T, Saijoh K, Fukase M, Chihara K Calcitonin directly acts on mouse osteoblastic MC3T3-E1 cells to stimulate mRNA expression of c-fos, insulin-like growth factor-1 and osteoblastic phenotypes (type 1 collagen and osteocalcin). Biochem Biophys Res Commun 1994 199:876-80 PubMed ID: 8135834 DOI: 10.1006/bbrc.1994.1310

1994 Tsukamoto T, Matsui T, Takaishi T, Ito M, Fukase M, Chihara K Retinoic acid differentially affects platelet-derived growth factor-regulated cell growth of mouse osteoblast-like cells Cell Growth Differ 1994 5:207-212 PubMed ID: 8180134

2590 Yamaguchi A, Katagiri T, Ikeda T, Wozney, J M, Rosen V, Wang, E A, Kahn, A J, Suda T, Yoshiki S Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro. J cell Biol 1991 113:681-687 PubMed ID: 1849907 DOI: 10.1083/jcb.113.3.681

1992 Hiura K, Sumitani K, Kawata T, Higashino K, Okawa M, Sato T, Hakeda Y, Kumegawa M Mouse osteoblastic cells (MC3T3-E1) at different stages of differentiation have opposite effects on osteoclastic cell formation. Endocrinology 1991 128:1630-7 PubMed ID: 1999177 DOI: 10.1210/endo-128-3-1630

1991 Hakeda Y, Nakatani Y, Hiramatsu M, Kurihara N, Tsunoi M, Ikeda E, Kumegawa M Inductive effects of prostaglandins on alkaline phosphatase in osteoblastic cells, clone MC3T3-E1 J Biochem 1985 97:97-104 PubMed ID: 2581942 DOI: 10.1093/oxfordjournals.jbchem.a135072

1849 Sudo H, Kodama, H A, Amagai Y, Yamamoto S, Kasai S In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol 1983 96:191-198 PubMed ID: 6826647 DOI: 10.1083/jcb.96.1.191

1848 Kodama,H., Amagai,Y., Sudo,H., Kasai,S. and Yamamoto,S. Establishment of a clonal osteogenic cell line from newborn mouse calvaria Jpn J Oral Biol 1981 23:899-901 DOI: 10.2330/joralbiosci1965.23.899

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22396 Wang Y, Yu X, Sun F, Fu Y, Hu T, Shi Q, Man Q. METTL14 Mediates Glut3 m6A methylation to improve osteogenesis under oxidative stress condition. Redox Rep 2025 30(1):2435241 PubMed ID: 39737912 DOI: 10.1080/13510002.2024.2435241

22406 Yamashita Y, Hayashi M, Liu A, Sasaki F, Tsuchiya Y, Takayanagi H, Saito M, Nakashima T. Fam102a translocates Runx2 and Rbpjl to facilitate Osterix expression and bone formation. Nat Commun 2025 16(1):9 PubMed ID: 39747056 DOI: 10.1038/s41467-024-55451-z

22407 Makiyama F, Kawase S, Omi AW, Tanikawa Y, Kotani T, Shirayama T, Nishimura N, Kurihara T, Saito N, Takahashi J, Uemura T. Differential effects of structurally different lysophosphatidylethanolamine species on proliferation and differentiation in pre-osteoblast MC3T3-E1 cells. Sci Rep 2025 15(1):466 PubMed ID: 39747517 DOI: 10.1038/s41598-024-84176-8

22470 Zheng X, Weng Y, Satoh A, Tanai A, Ikegame M, Kimura K, Yoshitani N, Xie X, Okamura H. PTPA localized in the Golgi apparatus plays an important role in osteoblast differentiation. Biochem Biophys Res Commun 2025 748:151329 PubMed ID: 39827549 DOI: 10.1016/j.bbrc.2025.151329

22480 Seki A, Kajiwara K, Teramachi J, Egusa M, Miyawaki T, Sawa Y. Exacerbation of diabetes due to F. Nucleatum LPS-induced SGLT2 overexpression in the renal proximal tubular epithelial cells. BMC Nephrol 2025 26(1):38 PubMed ID: 39856606 DOI: 10.1186/s12882-025-03965-z

22546 Izumiya M, Nobuoka H, Endo H, Ueno R, Mimura M, Saito N, Haniu H. Genetic Profiling of MC3T3-E1 Cells in Different Media: Implications for In Vitro Screening Development. Biomedicines 2025 13(2) PubMed ID: 40002902 DOI: 10.3390/biomedicines13020489

22724 Yutoku M, Fujita K, Chiba N, Tada R, Ohnishi T, Sugimura M, Matsuguchi T. Early Growth Response 1 Plays an Essential Role in Proinflammatory and Osteoclastogenic Activities of Lipopolysaccharide-Stimulated Osteoblasts. FASEB J 2025 39(7):e70532 PubMed ID: 40193242 DOI: 10.1096/fj.202402623R

22735 Kumeta M, Otani M, Toyoda M, Yoshimura SH. Acoustic modulation of mechanosensitive genes and adipocyte differentiation. Commun Biol 2025 8(1):595 PubMed ID: 40240542 DOI: 10.1038/s42003-025-07969-1

22759 Kurihara T, Shimamura M, Etani Y, Noguchi T, Fukuda Y, Ochiai N, Goshima A, Miura T, Hirao M, Sugimoto A, Ju N, Yamakawa S, Kanamoto T, Nakata K, Okada S, Ebina K. RANKL-derived peptide MHP1-AcN attenuates ovariectomy-induced osteoporosis by targeting RANK and TNFR1 in mice Bone 2025 117440 PubMed ID: 40032017 DOI: 10.1016/j.bone.2025.117440

22827 Sasagawa K, Domon H, Hirayama S, Maekawa T, Isono T, Tabeta K, Terao Y. Secretory leucocyte protease inhibitor regulates bone metabolism and inflammation in experimental mouse periodontitis. Commun Biol 2025 8(1):760 PubMed ID: 40379839 DOI: 10.1038/s42003-025-08197-3

22828 Mujtaba AG, Altunay BB, Pinarbasi B, Topuz B, Yilgor P, Karakeçili A. Zr-based metal-organic framework nanocrystals improve the osteoinductivity and osteogenicity of alginate/methyl cellulose bioink. Int J Biol Macromol 2025 PubMed ID: 40381770 DOI: 10.1016/j.ijbiomac.2025.144255

22966 Banerjee K, Oyane A, Nakamura M, Inose T, Nishida E, Shitomi K, Miyaji H. Integration of dual drugs into a collagen scaffold by a combination of apatite coating and impregnation with apatite particles for periodontal regeneration. RSC Adv 2025 PubMed ID: 40491789 DOI: 10.1039/d5ra02963e

22997 Akter R, Awais M, Morshed MN, Kim JH, Kong BM, Lee DW, Choi SK, Lee CS, Ahn JC, Yang DC. Synergistic Effect of Stauntonia hexaphylla (Thunb.) Decne Fruit and Leaf on RAW 264.7 Osteoclast and MC3T3-E1 Osteoblast Differentiation. Biomolecules 2025 15(6) PubMed ID: 40563484 DOI: 10.3390/biom15060844

19665 Reziwanguli Aili, Hidemi Nakata, Munemitsu Miyasaka, Shinji Kuroda, Yukihiko Tamura, Taishi Yokoi, Masakazu Kawashita, Yasushi Shimada, Shohei Kasugai, Eriko Marukawa Processing, Characterization, and in Vivo Evaluation of Poly(l-lactic acid)-Fish Gelatin Electrospun Membranes for Biomedical Applications Journal of Dental Sciences 2024 19:900-908 PubMed ID: 38618111 DOI: 10.1016/j.jds.2023.07.016

19890 Miura T, Etani Y, Noguchi T, Hirao M, Takami K, Goshima A, Kurihara T, Fukuda Y, Ochiai N, Kanamoto T, Nakata K, Okada S, Ebina K. Iguratimod suppresses sclerostin and receptor activator of NF-κB ligand production via the extracellular signal-regulated kinase/early growth response protein 1/tumor necrosis factor alpha pathway in osteocytes and ameliorates disuse osteoporosis in mice Bone 2024 181:117026 PubMed ID: 38325651 DOI: 10.1016/j.bone.2024.117026

19914 Yun J, Nam IH, Lee H, Jo YK, Lee H, Jun SH, Cha HJ. In Situ Photo-Crosslinkable Protein Bioadhesive for Bone Graft Fixation J Dent Res 2024 220345231224709 PubMed ID: 38317580 DOI: 10.1177/00220345231224709

19921 Chen T, Jinno Y, Atsuta I, Tsuchiya A, Obinata S, Iimori R, Kimura T, Ayukawa Y. Synergistic Effect of Nano Strontium Titanate Coating and Ultraviolet C Photofunctionalization on Osteogenic Performance and Soft Tissue Sealing of poly(ether-ether-ketone) ACS Biomater Sci Eng 2024 10(2):825-837 PubMed ID: 38267012 DOI: 10.1021/acsbiomaterials.3c01684

21536 Kutsuna S, Sugiyama G, Komiyama T, Kamohara H, Ohyama Y, Kumamaru W, Yamada T. TNF-α-induced Inhibition of Protein Myristoylation Via Binding Between NMT1 and Sorbs2 in Osteoblasts. In Vivo 2024 38(1):107-113 PubMed ID: 38148048 DOI: 10.21873/invivo.13416

21551 Nepal S, Si J, Ishikawa S, Nishikawa M, Sakai Y, Akimoto AM, Okada H, Ohba S, Chung UI, Sakai T, Hojo H. Injectable phase-separated tetra-armed poly(ethylene glycol) hydrogel scaffold allows sustained release of growth factors to enhance the repair of critical bone defects. Regen Ther 2024 25:24-34 PubMed ID: 38108043 DOI: 10.1016/j.reth.2023.11.008

21569 Sirisereephap K, Tamura H, Lim JH, Surboyo MDC, Isono T, Hiyoshi T, Rosenkranz AL, Sato-Yamada Y, Domon H, Ikeda A, Hirose T, Sunazuka T, Yoshiba N, Okada H, Terao Y, Maeda T, Tabeta K, Chavakis T, Hajishengallis G, Maekawa T. A novel macrolide-Del-1 axis to regenerate bone in old age. iScience 2024 27(2):108798 PubMed ID: 38261928 DOI: 10.1016/j.isci.2024.108798

21599 Shimabukuro M, Morinobu M, Tsuchiya A, Kishida R, Kawashita M, Ishikawa K. Antibacterial and osteogenic thin films on Ti-6Al-4V surface formed by passivation process in copper hydroxide solution. Sci Technol Adv Mater 2024 25(1):2303327 PubMed ID: 38343528 DOI: 10.1080/14686996.2024.2303327

21606 Ma C, Izumiya M, Nobuoka H, Ueno R, Mimura M, Ueda K, Ishida H, Tomotsune D, Johkura K, Yue F, Saito N, Haniu H. Three-Dimensional Modeling with Osteoblast-like Cells under External Magnetic Field Conditions Using Magnetic Nano-Ferrite Particles for the Development of Cell-Derived Artificial Bone. Nanomaterials (Basel) 2024 14(3) PubMed ID: 38334522 DOI: 10.3390/nano14030251

21689 Saito K, Toyoda H, Okada M, Oh JS, Nakazawa K, Ban Y, Orita K, Shimatani A, Yao H, Shirafuji T, Nakamura H. Fracture healing on non-union fracture model promoted by non-thermal atmospheric-pressure plasma. PLoS One 2024 19(4):e0298086 PubMed ID: 38626076 DOI: 10.1371/journal.pone.0298086

21751 Kawa Y, Shindo M, Ohgane J, Inui M. Epigenome editing revealed the role of DNA methylation of T-DMR/CpG island shore on Runx2 transcription. Biochem Biophys Rep 2024 38:101733 PubMed ID: 38799114 DOI: 10.1016/j.bbrep.2024.101733

21808 Dong Z, Hu B, Wang S, Wang M, Sun S, Liu X, Li D, Wu D. LncRNA MAGI2-AS3 promotes fracture healing through downregulation of miR-223-3p. J Orthop Surg Res 2024 19(1):370 PubMed ID: 38907263 DOI: 10.1186/s13018-024-04850-5

21820 Shiraishi T, Sato K. Real-time imaging of intracellular deformation dynamics in vibrated adherent cell cultures. Biotechnol Bioeng 2024 PubMed ID: 38961714 DOI: 10.1002/bit.28793

21838 Tanaka SM. Development of a composite using calcined bone powder and silane cross-linked alginate as bone substitute material. J Biomed Mater Res B Appl Biomater 2024 112(8):e35457 PubMed ID: 39032140 DOI: 10.1002/jbm.b.35457

21953 Hayashi K, Shimabukuro M, Zhang C, Taleb Alashkar AN, Kishida R, Tsuchiya A, Ishikawa K. Silver phosphate-modified carbonate apatite honeycomb scaffolds for anti-infective and pigmentation-free bone tissue engineering. Mater Today Bio 2024 27:101161 PubMed ID: 39155941 DOI: 10.1016/j.mtbio.2024.101161

22003 Kang I, Koo M, Jun JH, Lee J. Effect of nicotinamide mononucleotide on osteogenesis in MC3T3-E1 cells against inflammation-induced by lipopolysaccharide Clin Exp Reprod Med 2024 51(3):236-246 PubMed ID: 38599888 DOI: 10.5653/cerm.2023.06744

22010 Iwamae M, Tamai K, Nishino K, Orita K, Kobayashi Y, Terai H, Nakamura H. Does cessation of combustible cigarette and heated tobacco product smoking immediately following a fracture benefit fracture healing? In vivo and in vitro validation. Biochem Biophys Res Commun 2024 736:150512 PubMed ID: 39142235 DOI: 10.1016/j.bbrc.2024.150512

22067 Machado A, Gama M, Martins JA. Development of a dextrin-vitamin D3 micelle nanocarrier for the antimicrobial peptide LLKKK18 as a potential therapeutic agent for bone infections. J Mater Chem B 2024 PubMed ID: 39392350 DOI: 10.1039/d4tb00903g

22090 Kaneko M, Takizawa N, Wakabayashi T, Kaneoka H, Ito A. Amphiphilic phospholipid polymers as a cryoprotectant for vitrification and nanowarming of rat livers. J Biosci Bioeng 2024 PubMed ID: 39455294 DOI: 10.1016/j.jbiosc.2024.10.003

22110 Ninomiya H, Fukuda S, Nishida-Fukuda H, Shibata Y, Sato T, Nakamichi Y, Nakamura M, Udagawa N, Miyazawa K, Suzuki T. Osteoprotegerin secretion and its inhibition by RANKL in osteoblastic cells visualized using bioluminescence imaging. Bone 2024 117319 PubMed ID: 39500402 DOI: 10.1016/j.bone.2024.117319

22136 Yun J, Woo HT, Lee S, Cha HJ. Visible light-induced simultaneous bioactive amorphous calcium phosphate mineralization and in situ crosslinking of coacervate-based injectable underwater adhesive hydrogels for enhanced bone regeneration. Biomaterials 2024 315:122948 PubMed ID: 39522352 DOI: 10.1016/j.biomaterials.2024.122948

22150 Miyata N, Mori S, Murakami T, Bizenjima T, Seshima F, Imamura K, Saito A. Combined Effects of Fibroblast Growth Factor-2 and Carbonate Apatite Granules on Periodontal Healing: An In Vivo and In Vitro Study. Biomedicines 2024 12(8) PubMed ID: 39200129 DOI: 10.3390/biomedicines12081664

22156 Furuichi T, Hirai H, Kitahara T, Bun M, Ikuta M, Ukon Y, Furuya M, Oreffo ROC, Janeczek AA, Dawson JI, Okada S, Kaito T. Nanoclay gels attenuate BMP2-associated inflammation and promote chondrogenesis to enhance BMP2-spinal fusion. Bioact Mater 2024 44:474-487 PubMed ID: 39559426 DOI: 10.1016/j.bioactmat.2024.10.027

22163 Sato S, Hanai T, Kanamoto T, Kawano F, Hikida M, Yokoi H, Take Y, Magome T, Ebina K, Mae T, Tanaka H, Nakata K. Vibration acceleration enhances proliferation, migration, and maturation of C2C12 cells and promotes regeneration of muscle injury in male rats. Physiol Rep 2024 12(4):e15905 PubMed ID: 38396237 DOI: 10.14814/phy2.15905

22177 Kim J, Niioka K, Maeda E, Matsumoto T. Application of hydrostatic pressure up-regulates sost gene expression in osteocytic spheroids. Biosci Biotechnol Biochem 2024 PubMed ID: 39558570 DOI: 10.1093/bbb/zbae165

22185 Effect of Partial Substitution of Zr for Ti Solvent on Young's Modulus, Strength, and Biocompatibility in Beta Ti Alloy Effect of Partial Substitution of Zr for Ti Solvent on Young's Modulus, Strength, and Biocompatibility in Beta Ti Alloy Materials (Basel) 2024 17(11):2548 PubMed ID: 38893812 DOI: 10.3390/ma17112548

22186 Suzuki H, Fujiwara Y, Ariyani W, Amano I, Ishii S, Ninomiya AK, Sato S, Takaoka A, Koibuchi N. 17β-Estradiol (E2) Activates Matrix Mineralization through Genomic/Nongenomic Pathways in MC3T3-E1 Cells Int J Mol Sci 2024 25(9):4727 PubMed ID: 38731947 DOI: 10.3390/ijms25094727

22187 Li QL, Wu YX, Zhang YX, Mao J, Zhang ZX. Enhancing osteogenic differentiation of MC3T3-E1 cells during inflammation using UPPE/β-TCP/TTC composites via the Wnt/β-catenin pathway RSC Adv 2024 14(3):1527-1537 PubMed ID: 38179095 DOI: 10.1039/d3ra05529a

22249 Miyake R, Shimabukuro M, Terauchi M, Marukawa E, Kawashita M. Amorphous Magnesium Coating for Achieving Functional Changes from Antibacterial to Osteogenic Activities. ACS Appl Bio Mater 2024 PubMed ID: 39632261 DOI: 10.1021/acsabm.4c01341

22297 Mardiyantoro F, Chiba N, Seong CH, Tada R, Ohnishi T, Nakamura N, Matsuguchi T. Two-sided function of osteopontin during osteoblast differentiation. J Biochem 2024 PubMed ID: 39658208 DOI: 10.1093/jb/mvae080

22317 Yamamichi G, Kato T, Arakawa N, Ino Y, Ujike T, Nakano K, Koh Y, Motoyama Y, Outani H, Myoba S, Ishizuya Y, Yamamoto Y, Hatano K, Kawashima A, Fukuhara S, Uemura H, Okada S, Morii E, Nonomura N, Uemura M. GDF15 propeptide promotes bone metastasis of castration-resistant prostate cancer by augmenting the bone microenvironment Biomark Res 2024 12(1):147 PubMed ID: 39587633 DOI: 10.1186/s40364-024-00695-6

22356 Sampei C, Kato K, Arasaki Y, Kimura Y, Konno T, Otsuka K, Kohara Y, Noda M, Ezura Y, Hayata T. Gprc5a is a novel parathyroid hormone-inducible gene and negatively regulates osteoblast proliferation and differentiation J Cell Physiol 2024 239(8):e31297 PubMed ID: 38769895 DOI: 10.1002/jcp.31297

22358 Jinyan Si, Shohei Ishikawa, Shant Nepal, Hiroyuki Okada, Ung-il Chung, Takamasa Sakai, Hironori Hojo Osteogenic differentiation capabilities of multiarm PEG hydrogels: involvement of gel–gel-phase separation in cell differentiation Polymer Journal 2024 DOI: 10.1038/s41428-024-00955-0

22494 Hayashi K, Takagane K, Itoh G, Kuriyama S, Koyota S, Meguro K, Ling Y, Abé T, Ohashi R, Yashiro M, Mizuno M, Tanaka M. Cell-cell contact-dependent secretion of large-extracellular vesicles from EFNBhigh cancer cells accelerates peritoneal dissemination Br J Cancer 2024 131(6):982-995 PubMed ID: 39003372 DOI: 10.1038/s41416-024-02783-8

22507 Sönmezer Açıkgöz D, Latifoğlu F, Toprak G, Baran M. Applications of a biocompatible alginate/pericardial fluid-based hydrogel for the production of a bioink in tissue engineering Biotechnol Appl Biochem 2024 2024 Dec 2 PubMed ID: 39623554 DOI: 10.1002/bab.2697

22692 Miyabe S, Fujinaga Y, Tsuchiya H, Fujimoto S. TiO2 nanotubes with customized diameters for local drug delivery systems J Biomed Mater Res B Appl Biomater 2024 112(7):e35445 PubMed ID: 38946669 DOI: 10.1002/jbm.b.35445

22695 Carvalho EO, Fernandes MM, Ivanova K, Rodriguez-Lejarraga P, Tzanov T, Ribeiro C, Lanceros-Mendez S. Multifunctional piezoelectric surfaces enhanced with layer-by-layer coating for improved osseointegration and antibacterial performance Colloids Surf B Biointerfaces 2024 243:114123 PubMed ID: 39079183 DOI: 10.1016/j.colsurfb.2024.114123

22721 Aoyagi H, Okada M, Yanagimoto H, Matsumoto T. Investigation on bacterial capture and antibacterial properties of acid-treated Ti surface Dent Mater 2024 40(2):318-326 PubMed ID: 38042700 DOI: 10.1016/j.dental.2023.11.018

22761 Asayama T, Takada A, Mikami Y, Yamaguchi H, Tamura M, Matsumoto K, Miyake K, Yonehara Y, Tsuda H. Possible roles of short-chain fatty acids produced by oral bacteria in the development of alveolar osteitis J Oral Sci 2024 66(2):102-106 PubMed ID: 38417878 DOI: 10.2334/josnusd.23-0410

22762 Katsuya Sato, Taira Eihara Frequency-dependent characteristics of osteoblast calcium signaling responses to microvibrational stimulation Journal of Biorheology 2024 38:55-64 DOI: 10.17106/jbr.38.55

22763 Takahashi M, Shiraki S, Lee S, Obata A. Niobium-Containing Phosphate Glasses Prepared by the Liquid-Phase Method Int J Mol Sci 2024 26(1):161. PubMed ID: 39796019 DOI: 10.3390/ijms26010161

22830 Muhammad Amir Jamilludin, Koichiro Hayashi, Yusril Yusuf, Kunio Ishikawa Fabrication of magnesium-doped biphasic calcium phosphate granules with sea urchin spine-derived porous structure Ceramics International 2024 50:25988-25999 DOI: 10.1016/j.ceramint.2024.04.341

22847 Takeki Hamasaki, Kiichiro Teruya, Yoshinori Katakura Exposing Differentiated Osteoblast-Like MC3T3-E1 Cells to Extremely Low-Frequency Electric Fields Has Calcification-Promoting Effects IEEE Transactions on Dielectrics and Electrical Insulation 2024 31:642-648 DOI: 10.1109/tdei.2024.3374241

22848 Chiaki Mandai, Hirohito Kato, Kazutaka Imai, Chizuko Ogata, Yoichiro Taguchi, Makoto Umeda Effects of a Low Glucose Condition on Proliferation, Differentiation and Autophagy in Mouse Osteoblast-Like Cells Journal of Hard Tissue Biology 2024 33:11-18 DOI: 10.2485/jhtb.33.11

22849 Akihisa Utsu, Natsuko Tanabe, Soichiro Manaka, Keiko Tomita, Risa Ichikawa, Misae Ono, Yuma Masai, Naoto Suzuki, Mitsuru Motoyoshi Low-Intensity Pulsed Ultrasound Induced Osteoblast Differentiation Mediated by the PYK2-ERK2 Signaling in MC3T3-E1 Cells. Journal of Hard Tissue Biology 2024 33:47-54 DOI: 10.2485/jhtb.33.47

22850 Ikeda R, Kimura C, Nihashi Y, Umezawa K, Shimosato T, Takaya T. Osteogenic CpG Oligodeoxynucleotide, iSN40, Inhibits Osteoclastogenesis in a TLR9-Dependent Manner Life (Basel) 2024 14(12):1572 PubMed ID: 39768281 DOI: 10.3390/life14121572

22851 Le T. Bang, Bui D. Long, Phung X. Lan, Xingling Shi, Nguyen T. V. Thanh, S. Ramesh Effect of strontium substitution on the properties of mesoporous carbonate apatite for biomedical applications Journal of the Australian Ceramic Society 2024 60:1315-1329 DOI: 10.1007/s41779-024-01041-7

22852 Tomomi I, Kanzaki H, Shimoyama M, Tohyama S, Ishikawa M, Katsumata Y, Arai C, Wada S, Manase S, Tomonari H. Activation of Nuclear Factor Erythroid 2-Related Factor 2 Transcriptionally Upregulates Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Expression and Inhibits Ectopic Calcification in Mice Antioxidants (Basel) 2024 13(8):896 PubMed ID: 39199142 DOI: 10.3390/antiox13080896

22853 Ochiai N, Etani Y, Noguchi T, Miura T, Kurihara T, Fu The pivotal role of the Hes1/Piezo1 pathway in the pathophysiology of glucocorticoid-induced osteoporosis JCI Insight 2024 9(23):e179963 PubMed ID: 39641269 DOI: 10.1172/jci.insight.179963

17725 Fujii S, Ohta T, Ehama R, Irikida M, Nomura S, Shoyama Y, Uto T. Development of an indirect competitive enzyme-linked immunosorbent assay for formononetin and its application in a cell-based assay using MC3T3-E1 cells Food Chem 2023 403:134339 PubMed ID: 36174344 DOI: 10.1016/j.foodchem.2022.134339

17728 Trang LT, Le HV, Hiromoto S, Minho O, Kobayashi E, Nguyen NV, Cao NQ. In vitro cellular biocompatibility and in vivo degradation behavior of calcium phosphate-coated ZK60 magnesium alloy Biomed Mater 2023 18(3) PubMed ID: 36827743 DOI: 10.1088/1748-605X/acbf16

17733 Hikaru Tamura, Tomoki Maekawa, Hisanori Domon, Kridtapat Sirisereephap, Toshihito Isono, Satoru Hirayama, Takumi Hiyoshi, Karin Sasagawa, Fumio Takizawa, Takeyasu Maeda, Yutaka Terao, Koichi Tabeta Erythromycin Restores Osteoblast Differentiation and Osteogenesis Suppressed by Porphyromonas gingivalis Lipopolysaccharide Pharmaceuticals 2023 16:16 PubMed ID: 37259446 DOI: 10.3390/ph16020303

17735 Teresa Marques-Almeida, Senentxu Lanceros-Mendez, Clarisse Ribeiro Degradation and mineralization of electroactive poly(3-hydroxybutyrate-co-3-hydroxyvalerate) electrospun fibers for bone tissue engineering Reactive and Functional Polymers 2023 182:105475 DOI: 10.1016/j.reactfunctpolym.2022.105475

17761 Horie M, Chiba R, Umemoto S, Tajika M. Particulate beta-tricalcium phosphate and hydroxyapatite doped with silver promote in vitro osteoblast differentiation in MC3T3-E1 cells Biomed Mater Eng 2023 Apr 20 PubMed ID: 37125541 DOI: 10.3233/BME-211376

19570 Nur Zulaikha Mohamad Zaidi, Ahmed Hafedh Mohammed Mohammed, Mamun Khan Sujon, Khairul Anuar Shariff, Mohamad Hafizi Abu Bakar Behavioural responses of bone-like cells on dense and porous dicalcium phosphate dihydrate-coated β-tricalcium phosphate granules Journal of the Australian Ceramic Society 2023 59:1423-1431 DOI: 10.1007/s41779-023-00925-4

19571 Hirohito KATO, Yoichiro TAGUCHI, Runbo LI, Chiaki MANDAI, Masahiro NOGUCHI, Kei SHIOMI, Hideki AKIMOTO, Sho MIZUTANI, Tomoko KANDA, Chizuko OGATA, Makoto UMEDA Inhibition of Intracellular Glucose Metabolism by 2-deoxyglucose Suppresses Proliferation and Differentiation of Mouse Osteoblast-like Cells Endodontology and Periodontology 2023 3:144-151 DOI: 10.11471/odep.2023-017

19572 Satoshi Migita Surface roughness and its role in mediating cell adhesion on cobalt‐chromium‐molybdenum alloys Biosurface and Biotribology 2023 9: 161-168 DOI: 10.1049/bsb2.12068

19573 Takami K, Okamoto K, Etani Y, Hirao M, Miyama A, Okamura G, Goshima A, Miura T, Kurihara T, Fukuda Y, Kanamoto T, Nakata K, Okada S, Ebina K. Anti-NF-κB peptide derived from nuclear acidic protein attenuates ovariectomy-induced osteoporosis in mice JCI Insight 2023 8(22):e171962 PubMed ID: 37991021 DOI: 10.1172/jci.insight.171962

19574 Haruhiko Takemoto, Keito Sonoda, Kanae Ike, Yoichi Saito, Yoshitaka Nakanishi, Yuta Nakashima Development of Cell Micropatterning Technique Using Laser Processing of Alginate Gel Journal of Robotics and Mechatronics 2023 35:1185-1192 DOI: 10.20965/jrm.2023.p1185

19575 Takemoto F, Uchida-Fukuhara Y, Kamioka H, Okamura H, Ikegame M. Mechanical stretching determines the orientation of osteoblast migration and cell division Anat Sci Int 2023 98(4):521-528. PubMed ID: 37022568 DOI: 10.1007/s12565-023-00716-8

19576 Nami Tsuchiyama, Yukihiko Tamura, Tadamu Gondo, Masaomi Ikeda, Yasushi Shimada The effect of ions used in bioactive dental materials on proliferation and differentiation of MC3T3-E1 cells Asian Pacific Journal of Dentistry 2023 23:15-19 DOI: 10.47416/apjod.23-0002

19604 Suresh Kumar H, Barnett EN, Fowlkes JL, Kalaitzoglou E, Annamalai RT. Biomechanical Stimulation of Muscle Constructs Influences Phenotype of Bone Constructs by Modulating Myokine Secretion JBMR Plus 2023 7(11):e10804 PubMed ID: 38025033 DOI: 10.1002/jbm4.10804

19639 Verlinden L, Doms S, Janssens I, Meyer MB, Pike JW, Carmeliet G, Verstuyf A. Neuropilin 2 in osteoblasts regulates trabecular bone mass in male mice Front Endocrinol (Lausanne) 2023 14:1223021 PubMed ID: 37600714 DOI: 10.3389/fendo.2023.1223021

19645 R. Brito-Pereira, P. Martins, S. Lanceros-Mendez, C. Ribeiro Polymer-based magnetoelectric scaffolds for wireless bone repair: The fillers’ effect on extracellular microenvironments Composites Science and Technology 2023 243:110263 DOI: 10.1016/j.compscitech.2023.110263

19661 Shiga T, Kato H, Saito A, Onodera S, Shibahara T, Takano M, Azuma T. Three-dimensional Culture Using Atelocollagen Sponge and Self-assembling Peptide Hydrogel Bull Tokyo Dent Coll 2023 64(2):43-54 PubMed ID: 37183012 DOI: 10.2209/tdcpublication.2022-0027

19703 Li R, Kato H, Fumimoto C, Nakamura Y, Yoshimura K, Minagawa E, Omatsu K, Ogata C, Taguchi Y, Umeda M. Essential Amino Acid Starvation-Induced Oxidative Stress Causes DNA Damage and Apoptosis in Murine Osteoblast-like Cells Int J Mol Sci 2023 24(20):15314 PubMed ID: 37894999 DOI: 10.3390/ijms242015314

19723 Megumi Fuse, Tomomi Hashizume-Takizawa, Chieko Taguchi, Kou Fujita-Nakajima, Takao Kuwada-Kusunose, Hiroyuki Okada Effects of Adhesive or Non-adhesive Protein-immobilized Bioactive（Lactic Acid-ε-caprolactone）Films on Mouse Osteoblast-like Cells International Journal of Oral-Medical Sciences 2023 22:1-10 DOI: 10.5466/ijoms.22.1

19779 Yusuke Tsutsumi, Harumi Tsutsumi, Tomoyo Manaka, Peng Chen, Maki Ashida, Hideki Katayama, Takao Hanawa Development of a Surface Treatment to Achieve Long-Lasting Antimicrobial Properties and Non-Cytotoxicity through Simultaneous Incorporation of Ag and Zn via Two-Step Micro-Arc Oxidation Coatings 2023 13:627 DOI: 10.3390/coatings13030627

19805 Katsuya Sato, Tasuku Nakahara, Kazuyuki Minami Difference in the Osteoblastic Calcium Signaling Response Between Compression and Stretching Mechanical Stimuli Journal of Robotics and Mechatronics 2023 35:1135-1142 DOI: 10.20965/jrm.2023.p1135

19806 Morimoto Y, Hasegawa T, Hongo H, Yamamoto T, Maruoka H, Haraguchi-Kitakamae M, Nakanishi K, Yamamoto T, Ishizu H, Shimizu T, Yoshihara K, Yoshida Y, Sugaya T, Amizuka N. Phosphorylated pullulan promotes calcification during bone regeneration in the bone defects of rat tibiae Front Bioeng Biotechnol 2023 11:1243951 PubMed ID: 37885453 DOI: 10.3389/fbioe.2023.1243951

19889 Nagai S, Kitamura K, Kimura M, Yamamoto H, Katakura A, Shibukawa Y. Functional Expression of Mechanosensitive Piezo1/TRPV4 Channels in Mouse Osteoblasts Bull Tokyo Dent Coll 2023 64(1):1-11 PubMed ID: 36792153 DOI: 10.2209/tdcpublication.2022-0015

19949 Yoshinouchi S, Karouji K, Tominari T, Sugasaki M, Matsumoto C, Miyaura C, Hirata M, Itoh Y, Inada M. Prostate cancer expressing membrane-bound TGF-α induces bone formation mediated by the autocrine effect of prostaglandin E2 in osteoblasts Biochem Biophys Res Commun 2023 644:40-48. PubMed ID: 36623397 DOI: 10.1016/j.bbrc.2022.11.050

19950 Mady LJ, Zhong Y, Dhawan P, Christakos S. Role of Coactivator Associated Arginine Methyltransferase 1 (CARM1) in the Regulation of the Biological Function of 1,25-Dihydroxyvitamin D3 Cells 2023 12(10):1407 PubMed ID: 37408241 DOI: 10.3390/cells12101407

19988 Tanabe N, Tomita K, Manaka S, Ichikawa R, Takayama T, Kawato T, Ono M, Masai Y, Utsu A, Suzuki N, Sato S. Co-Stimulation of AGEs and LPS Induces Inflammatory Mediators through PLCγ1/JNK/NF-κB Pathway in MC3T3-E1 Cells Cells 2023 12(10):1383 PubMed ID: 37408216 DOI: 10.3390/cells12101383

20844 Suzuki M, Kimura T, Nakano Y, Kobayashi M, Okada M, Matsumoto T, Nakamura N, Hashimoto Y, Kishida A. Preparation of mineralized pericardium by alternative soaking for soft-hard interregional tissue application. J Biomed Mater Res A 2023 111(2):198-208 PubMed ID: 36069375 DOI: 10.1002/jbm.a.37445

21061 Wang H, Tenkumo T, Nemoto E, Kanda Y, Ogawa T, Sasaki K. Introduction of tenomodulin by gene transfection vectors for rat bone tissue regeneration. Regen Ther 2023 22:99-108 PubMed ID: 36712960 DOI: 10.1016/j.reth.2022.12.008

21062 Sitosari H, Morimoto I, Weng Y, Zheng Y, Fukuhara Y, Ikegame M, Okamura H. Inhibition of protein phosphatase 2A by okadaic acid induces translocation of nucleocytoplasmic O-GlcNAc transferase. Biochem Biophys Res Commun 2023 646:50-55 PubMed ID: 36706705 DOI: 10.1016/j.bbrc.2023.01.033

21117 Mori Y, Fujimori S, Kurishima H, Inoue H, Ishii K, Kubota M, Kawakami K, Mori N, Aizawa T, Masahashi N. Antimicrobial Properties of TiNbSn Alloys Anodized in a Sulfuric Acid Electrolyte. Materials (Basel) 2023 16(4) PubMed ID: 36837117 DOI: 10.3390/ma16041487

21126 Ueda K, Ma C, Izumiya M, Kuroda C, Ishida H, Uemura T, Saito N, Aoki K, Haniu H. Biocompatibility Evaluation of Carbon Nanohorns in Bone Tissues. Nanomaterials (Basel) 2023 13(2) PubMed ID: 36677997 DOI: 10.3390/nano13020244

21151 Rojasawasthien T, Usui M, Addison WN, Matsubara T, Shirakawa T, Tsujisawa T, Nakashima K, Kokabu S. Nobiletin, a NF-κB signaling antagonist, promotes BMP-induced bone formation. FASEB Bioadv 2023 5(2):62-70 PubMed ID: 36816515 DOI: 10.1096/fba.2022-00093

21263 Watanabe M, Yahagi T, Kamikura R, Kotani H, Miyake K, Matsuzaki K. Methoxyflavones isolated from the whole plant of Scutellaria rubropunctata Hayata var. rubropunctata promote osteoblast differentiation in MC3T3-E1 cells. J Nat Med 2023 PubMed ID: 37329417 DOI: 10.1007/s11418-023-01716-8

21266 Kim J, Kim BY, Lee JS, Jeong YM, Cho HJ, Park E, Kim D, Kim SS, Kim BT, Choi YJ, Won YY, Jin HS, Chung YS, Jeong SY. UBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis. Nat Commun 2023 14(1):3668 PubMed ID: 37339951 DOI: 10.1038/s41467-023-39448-8

21289 Inagaki T, Kim J, Tomida K, Maeda E, Matsumoto T. 3D quantitative assessment for nuclear morphology in osteocytic spheroid with optical clearing technique. Integr Biol (Camb) 2023 15 PubMed ID: 37314268 DOI: 10.1093/intbio/zyad007

21291 Li R, Kato H, Nakata T, Yamawaki I, Yamauchi N, Imai K, Taguchi Y, Umeda M. Essential amino acid starvation induces cell cycle arrest, autophagy, and inhibits osteogenic differentiation in murine osteoblast. Biochem Biophys Res Commun 2023 672:168-176 PubMed ID: 37354610 DOI: 10.1016/j.bbrc.2023.06.055

21359 Nakamura M, Araki H, Tsurushima H, Oyane A. Fabrication of water-dispersible and cell-stimulating calcium phosphate nanoparticles immobilizing basic fibroblast growth factor. Colloids Surf B Biointerfaces 2023 230:113502 PubMed ID: 37574618 DOI: 10.1016/j.colsurfb.2023.113502

21391 Nagai T, Sekimoto T, Kurogi S, Ohta T, Miyazaki S, Yamaguchi Y, Tajima T, Chosa E, Imasaka M, Yoshinobu K, Araki K, Araki M, Choijookhuu N, Sato K, Hishikawa Y, Funamoto T. Tmem161a regulates bone formation and bone strength through the P38 MAPK pathway. Sci Rep 2023 13(1):14639 PubMed ID: 37670024 DOI: 10.1038/s41598-023-41837-4

21421 Kim Y, Hamada K, Sekine K. The effect of supplementing the calcium phosphate cement containing poloxamer 407 on cellular activities. J Biomed Mater Res B Appl Biomater 2023 PubMed ID: 37772460 DOI: 10.1002/jbm.b.35335

21422 Inoue S, Li C, Hatakeyama J, Jiang H, Kuroki H, Moriyama H. Higher-intensity ultrasound accelerates fracture healing via mechanosensitive ion channel Piezo1. Bone 2023 177:116916 PubMed ID: 37777037 DOI: 10.1016/j.bone.2023.116916

21442 Kito H, Kawagishi R, Ryu T, Endo K, Kajikuri J, Giles WR, Ohya S. KCa3.1 regulates cell cycle progression by modulating Ca2+ signaling in murine preosteoblasts. J Pharmacol Sci 2023 153(3):142-152 PubMed ID: 37770155 DOI: 10.1016/j.jphs.2023.09.001

21443 Liu Q, Li Q, Hatakeyama M, Kitaoka T. Proliferation and differential regulation of osteoblasts cultured on surface-phosphorylated cellulose nanofiber scaffolds. Int J Biol Macromol 2023 253(Pt 3):126842 PubMed ID: 37703974 DOI: 10.1016/j.ijbiomac.2023.126842

21479 Uehara N, Shibusawa N, Mikami Y, Kyumoto-Nakamura Y, Sonoda S, Kato H, Yamaza T, Kukita T. Bone metastatic mammary tumor cell-derived extracellular vesicles inhibit osteoblast maturation via JNK signaling. Arch Biochem Biophys 2023 750:109821 PubMed ID: 37979903 DOI: 10.1016/j.abb.2023.109821

21528 Bunn RC, Adatorwovor R, Smith RR, Ray PD, Fields SE, Keeble AR, Fry CS, Uppuganti S, Nyman JS, Fowlkes JL, Kalaitzoglou E. Pharmacologic Inhibition of Myostatin With a Myostatin Antibody Improves the Skeletal Muscle and Bone Phenotype of Male Insulin-Deficient Diabetic Mice. JBMR Plus 2023 7(11):e10833 PubMed ID: 38025035 DOI: 10.1002/jbm4.10833

21537 Choi HS, Yun J, Jeong Y, Jo YK, Cha HJ. Self-controllable proteinic antibacterial coating with bacteria-triggered antibiotic release for prevention of periprosthetic infection. Biomaterials 2023 305:122457 PubMed ID: 38171117 DOI: 10.1016/j.biomaterials.2023.122457

17585 Machado A, Pereira I, Silva V, Pires I, Prada J, Poeta P, Costa L, Pereira JE, Gama M. Injectable hydrogel as a carrier of vancomycin and a cathelicidin-derived peptide for osteomyelitis treatment J Biomed Mater Res A 2022 110(11):1786-1800 PubMed ID: 36082973 DOI: 10.1002/jbm.a.37432

17670 Nihashi Y, Miyoshi M, Umezawa K, Shimosato T, Takaya T. Identification of a Novel Osteogenetic Oligodeoxynucleotide (osteoDN) That Promotes Osteoblast Differentiation in a TLR9-Independent Manner Nanomaterials (Basel) 2022 12(10):1680 PubMed ID: 35630904 DOI: 10.3390/nano12101680

17676 Hou J, Tamura Y, Lu HY, Takahashi Y, Kasugai S, Nakata H, Kuroda S. An In Vitro Evaluation of Selenium Nanoparticles on Osteoblastic Differentiation and Antimicrobial Properties against Porphyromonas gingivalis Nanomaterials (Basel) 2022 12(11):1850 PubMed ID: 35683706 DOI: 10.3390/nano12111850

17677 Masanobu Kamitakahara, Kanau Asahara, Hideaki Matsubara Calcium phosphate cements comprising spherical porous calcium phosphate granules: synthesis, structure, and properties Journal of Asian Ceramic Societies 2022 10:731-738 DOI: 10.1080/21870764.2022.2123514

17712 Qian Zhao, Takeshi Ueno, Peng Chen, Kosuke Nozaki, Tianbo Tan, Takao Hanawa, Noriyuki Wakabayashi Fabrication of micro-/submicro-/nanostructured surfaces on Ti–Zr alloy by varying H2SO4/H2O2 treatment conditions and investigations of fundamental properties of a typical surface Surfaces and Interfaces 2022 34:102390 DOI: 10.1016/j.surfin.2022.102390

17726 Yamamura Y, Miyoshi K, Mouri Y, Kudo Y, Miyamoto Y. miR-155-5p can be involved in acquisition of osseointegration on titanium surface In Vitro Cell Dev Biol Anim 2022 58(8):693-701 PubMed ID: 36053380 DOI: 10.1007/s11626-022-00718-2

17730 Toita R, Kang JH, Tsuchiya A. Phosphatidylserine liposome multilayers mediate the M1-to-M2 macrophage polarization to enhance bone tissue regeneration Acta Biomater 2022 154:583-596 PubMed ID: 36273800 DOI: 10.1016/j.actbio.2022.10.024

17731 Erika NISHIDA, Hirofumi MIYAJI, Tsutomu SUGAYA, Tsukasa AKASAKA Fabrication and Cell Behavior Assessment of Antibacterial Micro/nano-patterned Chitosan Films Nano Biomedicine 2022 14:1-8 DOI: 10.11344/nano.14.1

17734 Shimabukuro M, Hayashi K, Kishida R, Tsuchiya A, Ishikawa K. Surface functionalization with copper endows carbonate apatite honeycomb scaffold with antibacterial, proangiogenic, and pro-osteogenic activities Biomater Adv 2022 135:212751 PubMed ID: 35929223 DOI: 10.1016/j.bioadv.2022.212751

20397 Vukoje I, Lazić V, Sredojević D, Fernandes MM, Lanceros-Mendez S, Ahrenkiel SP, Nedeljković JM. Influence of glucose, sucrose, and dextran coatings on the stability and toxicity of silver nanoparticles. Int J Biol Macromol 2022 PubMed ID: 34800522 DOI: 10.1016/j.ijbiomac.2021.11.089

20461 Tan T, Zhao Q, Kuwae H, Ueno T, Chen P, Tsutsumi Y, Mizuno J, Hanawa T, Wakabayashi N. Surface properties and biocompatibility of sandblasted and acid-etched titanium-zirconium binary alloys with various compositions. Dent Mater J 2022 PubMed ID: 34866118 DOI: 10.4012/dmj.2021-210

15894 Moreira J, Fernandes MM, Carvalho EO, Nicolau A, Lazic V, Nedeljković JM, Lanceros-Mendez S. Exploring electroactive microenvironments in polymer-based nanocomposites to sensitize bacterial cells to low-dose embedded silver nanoparticles Acta Biomater 2022 S1742-7061(21)00505-5 PubMed ID: 34358697 DOI: 10.1016/j.actbio.2021.07.067

20465 Shimabukuro M, Hayashi K, Kishida R, Tsuchiya A, Ishikawa K. No-Observed-Effect Level of Silver Phosphate in Carbonate Apatite Artificial Bone on Initial Bone Regeneration. ACS Infect Dis 2022 PubMed ID: 34875165 DOI: 10.1021/acsinfecdis.1c00480

20500 Negishi T, Mihara N, Chiba T, D'Armiento J, Chada K, Maeda M, Igarashi M, Imai K. High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development.High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development.High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development.High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development. Biochem Biophys Res Commun 2022 590:68-74 PubMed ID: 34973532 DOI: 10.1016/j.bbrc.2021.12.093

20511 Chigama H, Kanetaka H, Furuya M, Yokota K, Kawashita M. Indirect cytotoxicity evaluations of antibacterial raw silk fabric doped with calcium, copper and zinc on fibroblasts and osteoblasts. J Biomater Appl 2022 8853282211058941 PubMed ID: 34984930 DOI: 10.1177/08853282211058941

20532 Patty DJ, Nugraheni AD, Ana ID, Yusuf Y. In vitro bioactivity of 3D microstructure hydroxyapatite/collagen based-egg white as an antibacterial agent. J Biomed Mater Res B Appl Biomater 2022 PubMed ID: 35040555 DOI: 10.1002/jbm.b.35009

20539 Migita S, Wakabayashi K, Yamazaki T. Binding stability of peptides to Co-Cr-Mo alloy affects proliferation and differentiation of osteoblast. Biotechnol Bioeng 2022 PubMed ID: 35067921 DOI: 10.1002/bit.28041

20549 Ikezaki-Amada K, Miyamoto Y, Sasa K, Yamada A, Kinoshita M, Yoshimura K, Kawai R, Yano F, Shirota T, Kamijo R. Extracellular acidification augments sclerostin and osteoprotegerin production by Ocy454 mouse osteocytes. Biochem Biophys Res Commun 2022 597:44-51 PubMed ID: 35123265 DOI: 10.1016/j.bbrc.2022.01.111

20563 Sato H, Chen P, Ashida M, Tsutsumi Y, Harada H, Hanawa T. Evaluation of cytocompatibility and osteoconductivity of Zr-14Nb-5Ta-1Mo alloy with MC3T3-E1 cells. Dent Mater J 2022 PubMed ID: 35135939 DOI: 10.4012/dmj.2021-169

20527 Hayashi K, Shimabukuro M, Ishikawa K. Antibacterial Honeycomb Scaffolds for Achieving Infection Prevention and Bone Regeneration. ACS Appl Mater Interfaces 2022 PubMed ID: 35020349 DOI: 10.1021/acsami.1c20204

16319 Fukuyasu S, Kayashima H, Moribayashi A, Matsuoka S, Nagasaki A, Okawa H, Yatani H, Saeki M, Egusa H. Cell-Based Double-Screening Method to Identify a Reliable Candidate for Osteogenesis-Targeting Compounds Biomedicines 2022 10(2):426 PubMed ID: 35203635 DOI: 10.3390/biomedicines10020426

16323 Nomura S, Kono R, Imaoka M, Tazaki F, Okuno Y, Utsunomiya H, Takeda M, Nakamura M. Traditional Japanese apricot (Prunus mume) induces osteocalcin in osteoblasts Biosci Biotechnol Biochem 2022 zbac013 PubMed ID: 35150233 DOI: 10.1093/bbb/zbac013

16326 Patty DJ, Nugraheni AD, Ana ID, Yusuf Y. Dual functional carbonate-hydroxyapatite nanocomposite from Pinctada maxima and egg-white for bone tissue engineering J Biomater Sci Polym Ed 2022 1-20 PubMed ID: 35107394 DOI: 10.1080/09205063.2022.2036934

16327 Yoshida G, Kawabata T, Takamatsu H, Saita S, Nakamura S, Nishikawa K, Fujiwara M, Enokidani Y, Yamamuro T, Tabata K, Hamasaki M, Ishii M, Kumanogoh A, Yoshimori T. Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis Autophagy 2022 1-10 PubMed ID: 35025696 DOI: 10.1080/15548627.2021.2017587

16343 Chikahiro Imashiro, Yuta Ida, Shogo Miyata, Jun Komotori Titanium Culture Vessel Capable of Controlling Culture Temperature for Evaluation of Cell Thermotolerance MATERIALS TRANSACTIONS 2022 63:373-378 DOI: 10.2320/matertrans.mt-z2021018

16344 Waheed H, Farrukh S, Hussain A, Mukhtar A, Mubashir M, Saqib S, Ullah S, Peter AP, Khoo KS, Show PL. Green synthesized nano-cellulose polyethylene imine-based biological membrane. Food Chem Toxicol 2022 160:112773 PubMed ID: 34953965 DOI: 10.1016/j.fct.2021.112773

20644 Masaki Saito, Marina Hirano, Tomohiro Izumi, Yu Mori, Kentaro Ito, Yurika Saitoh, Nobuo Terada, Takeya Sato, Jun Sukegawa Cytoskeletal Protein 4.1G Is Essential for the Primary Ciliogenesis and Osteoblast Differentiation in Bone Formation International Journal of Molecular Sciences 2022 23:2094 PubMed ID: 35216233 DOI: 10.3390/ijms23042094

20653 Amir MS, Chiba N, Seong CH, Kusuyama J, Eiraku N, Ohnishi T, Nakamura N, Matsuguchi T. HIF-1α plays an essential role in BMP9-mediated osteoblast differentiation through the induction of a glycolytic enzyme, PDK1. J Cell Physiol 2022 PubMed ID: 35411937 DOI: 10.1002/jcp.30752

20696 Karakeçili A, Korpayev S, Orhan K. Optimizing Chitosan/Collagen Type I/Nanohydroxyapatite Cross-linked Porous Scaffolds for Bone Tissue Engineering. Appl Biochem Biotechnol 2022 PubMed ID: 35543856 DOI: 10.1007/s12010-022-03962-0

20700 Elsheikh M, Kishida R, Hayashi K, Tsuchiya A, Shimabukuro M, Ishikawa K. Effects of pore interconnectivity on bone regeneration in carbonate apatite blocks. Regen Biomater 2022 9(1):rbac010 PubMed ID: 35449826 DOI: 10.1093/rb/rbac010

20715 Kondo T, Chiba T, Tousen Y. Short-chain fatty acids, acetate and propionate, directly upregulate osteoblastic differentiation. Int J Food Sci Nutr 2022 1-9 PubMed ID: 35616294 DOI: 10.1080/09637486.2022.2078285

16506 Sasaki Y, Nakatsuka R, Inouchi T, Masutani M, Nozaki T. Inhibition of Poly (ADP-Ribose) Glycohydrolase Accelerates Osteoblast Differentiation in Preosteoblastic MC3T3-E1 Cells Int J Mol Sci 2022 23(9):5041 PubMed ID: 35563432 DOI: 10.3390/ijms23095041

20721 Taga Y, Iwasaki Y, Tometsuka C, Funato N, Shigemura Y, Kusubata M, Mizuno K. Identification of a highly stable bioactive 3-hydroxyproline-containing tripeptide in human blood after collagen hydrolysate ingestion. NPJ Sci Food 2022 6(1):29 PubMed ID: 35662250 DOI: 10.1038/s41538-022-00144-4

16744 Yamashita S, Katsumi H, Sakane T, Yamamoto A. Phosphorylated Serine-Modified Polyamidoamine Dendrimer as an Osteoid Surface-Targeting Drug Carrier Mol Pharm 2022 19(7):2573-2582 PubMed ID: 35666687 DOI: 10.1021/acs.molpharmaceut.2c00271

16923 Yuan H, Ikegame M, Fukuhara Y, Takemoto F, Yu Y, Teramachi J, Weng Y, Guo J, Yamada D, Takarada T, Li Y, Okamura H, Zhang B. Vestigial-Like 3 Plays an Important Role in Osteoblast Differentiation by Regulating the Expression of Osteogenic Transcription Factors and BMP Signaling Calcif Tissue Int 2022 Jun 24 PubMed ID: 35750933 DOI: 10.1007/s00223-022-00997-7

20849 Coşkun S, Akbulut SO, Sarıkaya B, Çakmak S, Gümüşderelioğlu M. Formulation of chitosan and chitosan-nanoHAp bioinks and investigation of printability with optimized bioprinting parameters. Int J Biol Macromol 2022 PubMed ID: 36113600 DOI: 10.1016/j.ijbiomac.2022.09.078

20876 Takeyama H, Maruta M, Sato T, Kajimoto N, Fujii E, Matsuura T, Tsuru K. Fabrication of bioresorbable hydroxyapatite bone grafts through the setting reaction of calcium phosphate cement. Dent Mater J 2022 PubMed ID: 36002294 DOI: 10.4012/dmj.2022-045

20888 Kurita T, Li X, Bhawal UK. Crosstalk between microRNA-21-5p and the transcription factor Dec1 maintains osteoblast function. Biochem Biophys Res Commun 2022 632:32-39 PubMed ID: 36194917 DOI: 10.1016/j.bbrc.2022.09.090

20969 Sugimoto H, Fukuda S, Yokawa S, Hori M, Ninomiya H, Sato T, Miyazawa K, Kawai T, Furuno T, Inouye S, Goto S, Suzuki T. Visualization of osteocalcin and bone morphogenetic protein 2 (BMP2) secretion from osteoblastic cells by bioluminescence imaging. Biochem Biophys Res Commun 2022 635:203-209 PubMed ID: 36279682 DOI: 10.1016/j.bbrc.2022.10.042

20974 Migita S, Wakabayashi K. Analysis of disordered abrasive scratches on titanium surfaces and their impact on nuclear translocation of yes-associated protein. Sci Rep 2022 12(1):21705 PubMed ID: 36522392 DOI: 10.1038/s41598-022-26203-0

20982 Koike T, Mikami T, Tamura JI, Kitagawa H. Altered sulfation status of FAM20C-dependent chondroitin sulfate is associated with osteosclerotic bone dysplasia. Nat Commun 2022 13(1):7952 PubMed ID: 36572689 DOI: 10.1038/s41467-022-35687-3

21005 Marques-Almeida T, Correia V, Fernández Martín E, García Díez A, Ribeiro C, Lanceros-Mendez S. Piezoelectric and Magnetically Responsive Biodegradable Composites with Tailored Porous Morphology for Biotechnological Applications. ACS Appl Polym Mater 2022 4(12):8750-8763 PubMed ID: 36570789 DOI: 10.1021/acsapm.2c01114

17412 Wang J, Noguchi S, Takizawa T, Negishi Y, Morita R, Luo SS, Takizawa T. Placenta-specific lncRNA 1600012P17Rik is expressed in spongiotrophoblast and glycogen trophoblast cells of mouse placenta Histochem Cell Biol 2022 158(1):65-78 PubMed ID: 35486179 DOI: 10.1007/s00418-022-02109-w

21048 Kitaura Y, Nakamura U, Awada C, Yamaguchi M, Kim M, Ikeda Y, Matsuo Y, Moriishi T, Sawase T, Chung UI, Hojo H, Ohba S. Orally administrable peptides derived from egg yolk promote skeletal repair and ameliorate degenerative skeletal disorders in mouse models. Regen Ther 2022 21:584-595 PubMed ID: 36475024 DOI: 10.1016/j.reth.2022.11.002

17431 Nagashima D, Ishibashi Y, Kawaguchi S, Furukawa M, Toho M, Ohno M, Nitto T, Izumo N. Human Recombinant Lactoferrin Promotes Differentiation and Calcification on MC3T3-E1 Cells Pharmaceutics 2022 15(1):60 PubMed ID: 36678689 DOI: 10.3390/pharmaceutics15010060

17422 Nakai H, Inokoshi M, Nozaki K, Yoshihara K, Matsukawa A, Nagaoka N, Tonprasong W, Minakuchi S. Osteoblast Response of Additively Manufactured Zirconia and Alumina-Toughened Zirconia Materials (Basel) 2022 15(23):8685 PubMed ID: 36500180 DOI: 10.3390/ma15238685

17423 Miyazaki S, Funamoto T, Sekimoto T, Kurogi S, Ohta T, Nagai T, Tajima T, Imasaka M, Yoshinobu K, Araki K, Araki M, Choijookhuu N, Hishikawa Y, Chosa E. EPLINβ Is Involved in the Assembly of Cadherin-catenin Complexes in Osteoblasts and Affects Bone Formation Acta Histochem Cytochem 2022 55(3):99-11 PubMed ID: 35821749 DOI: 10.1267/ahc.22-00027

17425 Silva CA, Fernandes MM, Ribeiro C, Lanceros-Mendez S. Two- and three-dimensional piezoelectric scaffolds for bone tissue engineering Colloids Surf B Biointerfaces 2022 218:112708 PubMed ID: 35985127 DOI: 10.1016/j.colsurfb.2022.112708

17426 Karakeçili A, Topuz B, Ersoy FŞ, Şahin T, Günyakti A, Demirtaş TT. UiO-66 metal-organic framework as a double actor in chitosan scaffolds: Antibiotic carrier and osteogenesis promoter Biomater Adv 2022 136:212757 PubMed ID: 35929303 DOI: 10.1016/j.bioadv.2022.212757

17427 Ishihata K, Seong CH, Kibe T, Nakazono K, Mardiyantoro F, Tada R, Nishimura M, Matsuguchi T, Nakamura N. Lipoteichoic Acid and Lipopolysaccharides Are Affected by p38 and Inflammatory Markers and Modulate Their Promoting and Inhibitory Effects on Osteogenic Differentiation Int J Mol Sci 2022 23(20):1263 PubMed ID: 36293485 DOI: 10.3390/ijms232012633

17428 Bo-Young Kim, Do-Wan Kim, Eunkuk Park, Jeonghyun Kim, Chang-Gun Lee, Hyun-Seok Jin, Seon-Yong Jeong Identification of novel susceptibility genes associated with bone density and osteoporosis in Korean women Journal of Genetic Medicine 2022 19:63-75 DOI: 10.5734/jgm.2022.19.2.63

17429 Sungho Lee, Yoshihiko Sugimoto, Katsuya Kato, Tatsuya Miyajima, Makoto Sakurai, Fukue Nagata Development of beta-carotene-loaded poly(lactic acid)/hydroxyapatite core-shell nanoparticles for osteoblast differentiation Journal of Asian Ceramic Societies 2022 10:744-754 DOI: 10.1080/21870764.2022.2127262

17430 Tsuji K, Kimura S, Tateda K, Takahashi H. Protective effect of teriparatide against vancomycin-induced cytotoxicity in osteoblasts J Orthop Sci 2022 S0949-2658(22)00293-7. PubMed ID: 36371341 DOI: 10.1016/j.jos.2022.09.018

17434 Fernandes MM, Carvalho EO, Correia DM, Esperança JMSS, Padrão J, Ivanova K, Hoyo J, Tzanov T, Lanceros-Mendez S. Ionic Liquids as Biocompatible Antibacterial Agents: A Case Study on Structure-Related Bioactivity on Escherichia coli ACS Appl Bio Mater 2022 5(11):5181-5189 PubMed ID: 36260814 DOI: 10.1021/acsabm.2c00615

17436 Watanabe M, Yahagi T, Shirayama T, Miyake K, Kotani H, Ogawa T, Matsuzaki K. Effects of a Whole Plant Extract of Scutellaria rubropunctata var. rubropunctata on Bone Metabolism with Estrogen Receptor Activation Plants (Basel) 2022 11(16):2075 PubMed ID: 36015379 DOI: 10.3390/plants11162075

22188 Kaneko K, Miyamoto Y, Ida T, Morita M, Yoshimura K, Nagasaki K, Toba K, Sugisaki R, Motohashi H, Akaike T, Chikazu D, Kamijo R. 8-Nitro-cGMP suppresses mineralization by mouse osteoblasts J Clin Biochem Nutr 2022 71(3):191-197 PubMed ID: 36447486 DOI: 10.3164/jcbn.21-129

22189 Kunimatsu R, Hiraki T, Rikitake K, Nakajima K, Putranti NAR, Abe T, Ando K, Nakatani A, Sakata S, Tanimoto K. Effects of Human Deciduous Dental Pulp-Derived Mesenchymal Stem Cell-Derived Conditioned Medium on the Metabolism of HUVECs, Osteoblasts, and BMSCs Cells 2022 11(20):3222 PubMed ID: 36291089 DOI: 10.3390/cells11203222

22570 Tanaka M, Fujii S, Inoue H, Takahashi N, Ishimi Y, Uehara M. (S)-Equol Is More Effective than (R)-Equol in Inhibiting Osteoclast Formation and Enhancing Osteoclast Apoptosis, and Reduces Estrogen Deficiency-Induced Bone Loss in Mice J Nutr 2022 152(8):1831-1842 PubMed ID: 35675296 DOI: 10.1093/jn/nxac130

17724 Nguyen Xuan Thanh Tram, Kunio Ishikawa, Tran Hoang Minh, David Benson, Kanji Tsuru Characterization of carbonate apatite derived from chicken bone and its in-vitro evaluation using MC3T3-E1 cells Materials Research Express 2021 8:025401 DOI: 10.1088/2053-1591/abe018

17729 Bang Thi Le, S. Ramesh, Bui Duc Long, Nguyen Anh Son, Melvin Munar, Xingling Shi Effect of MgO addition on the sinterability, mechanical properties and biological cell activities of sintered silicon-substituted hydroxyapatite Journal of the Australian Ceramic Society 2021 57:857-868 DOI: 10.1007/s41779-021-00582-5

13248 Nishida E, Miyaji H, Shitomi K, Sugaya T, Akasaka T. Evaluation of antibacterial and cytocompatible properties of multiple-ion releasing zinc-fluoride glass nanoparticles. Dent Mater J 2021 40(1):157-164 PubMed ID: 32999216 DOI: 10.4012/dmj.2019-176

13407 Oka S, Li X, Zhang F, Tewari N, Ma R, Zhong L, Makishima M, Liu Y, Bhawal UK. MicroRNA-21 facilitates osteoblast activity. Biochem Biophys Rep 2021 PubMed ID: 33426313 DOI: 10.1016/j.bbrep.2020.100894

20047 Miyama A, Ebina K, Hirao M, Okamura G, Etani Y, Takami K, Goshima A, Miura T, Oyama S, Kanamoto T, Yoshikawa H, Nakata K. Effects of iguratimod on glucocorticoid-induced disorder of bone metabolism in vitro. J Bone Miner Metab 2021 PubMed ID: 33564917 DOI: 10.1007/s00774-021-01206-5

20056 Rojasawasthien T, Shirakawa T, Washio A, Tsujisawa T, Matsubara T, Inoue A, Takahama U, Nakashima K, Kokabu S. Vignacyanidin Polyphenols Isolated from Vigna Angularis Bean Promote Osteoblast Differentiation. In Vivo 2021 35(2):883-888 PubMed ID: 33622880 DOI: 10.21873/invivo.12328

13561 Seong CH, Chiba N, Kusuyama J, Subhan Amir M, Eiraku N, Yamashita S, Ohnishi T, Nakamura N, Matsuguchi T. Bone morphogenetic protein 9 (BMP9) directly induces Notch effector molecule Hes1 through the SMAD signaling pathway in osteoblasts FEBS Lett 2021 595(3):389-403 PubMed ID: 33264418 DOI: 10.1002/1873-3468.14016

20063 Nakamura K, Minamikawa H, Takahashi S, Yoshimura Y, Yawaka Y. N-acetylcysteine attenuates PGE2 and ROS production stimulated by 4-META/MMA-based resin in murine osteoblastic cells. Dent Mater J 2021 PubMed ID: 33642448 DOI: 10.4012/dmj.2020-275

20072 Kodama K, Valanezhad A, Khodaei M, Safaee S, Jafarnia S, Nesabi M, Abe S, Watanabe I, Murata H. A novel coating layer on zirconia using modified zinc phosphatizing method. Dent Mater J 2021 PubMed ID: 33692225 DOI: 10.4012/dmj.2020-253

13856 Kim J, Adachi T. Modulation of Sost Gene Expression Under Hypoxia in Three-Dimensional Scaffold-Free Osteocytic Tissue Tissue Eng Part A 2021 ;27(15-16):1037-1043 PubMed ID: 33040693 DOI: 10.1089/ten.TEA.2020.0228

14293 Shinji S, Umezawa K, Nihashi Y, Nakamura S, Shimosato T, Takaya T. Identification of the Myogenetic Oligodeoxynucleotides (myoDNs) That Promote Differentiation of Skeletal Muscle Myoblasts by Targeting Nucleolin Front Cell Dev Biol 2021 8:616706 PubMed ID: 33585451 DOI: 10.3389/fcell.2020.616706

20259 Chujo K, Jo JI, Tabata Y. Intracellular controlled release prolongs the time period of siRNA-based gene suppression. J Biomater Sci Polym Ed 2021 1-13 PubMed ID: 34348600 DOI: 10.1080/09205063.2021.1958183

15278 Masanori Horie, Sakiko Sugino, Atsumi Tada, Kazuhiro Nara Groundnut (Apios americana Medik) Extract Enhances the Osteoblast Differentiation of MC3T3-E1 Cells Natural Product Communications 2021 16:1934578X2110105 DOI: 10.1177/1934578x211010567

20337 Kim J, Kigami H, Adachi T. Comparative gene expression analysis for pre-osteoblast MC3T3-E1 cells under non-adhesive culture toward osteocyte differentiation. J Biosci Bioeng 2021 PubMed ID: 34556421 DOI: 10.1016/j.jbiosc.2021.09.004

15495 Shiva Jafarnia, Alireza Valanezhad, Shigeaki Abe, Sima Shahabi, Ikuya Watanabe Resin-based sealant containing sol–gel derived bioactive glass: ion release and biological response Journal of Sol-Gel Science and Technology 2021 DOI: 10.1007/s10971-021-05551-9

15498 Ge G, Yang S, Hou Z, Gan M, Tao H, Zhang W, Li W, Wang Z, Hao Y, Gu Y, Geng D. Theaflavin-3,3'-Digallate Promotes the Formation of Osteoblasts Under Inflammatory Environment and Increases the Bone Mass of Ovariectomized Mice Front Pharmacol 2021 12:648969 PubMed ID: 33833684 DOI: 10.3389/fphar.2021.648969

15528 Izumiya M, Haniu M, Ueda K, Ishida H, Ma C, Ideta H, Sobajima A, Ueshiba K, Uemura T, Saito N, Haniu H. Evaluation of MC3T3-E1 Cell Osteogenesis in Different Cell Culture Media Int J Mol Sci 2021 22(14):7752 PubMed ID: 34299372 DOI: 10.3390/ijms22147752

20489 Kaga N, Fujimoto H, Morita S, Yamaguchi Y, Matsuura T. Contact Angle and Cell Adhesion of Micro/Nano-Structured Poly(lactic-co-glycolic acid) Membranes for Dental Regenerative Therapy. Dent J (Basel) 2021 9(11) PubMed ID: 34821588 DOI: 10.3390/dj9110124

16039 Yasser Abdelrhman, Sengo Kobayashi, Satoshi Okano, Takeaki Okamoto, Mohamed Abdel-Hady Gepreel Biocompatibility of Anodized Low-Cost Ti-4.7Mo-4.5Fe Alloy Materials Science Forum 2021 1016:458-464 DOI: 10.4028/www.scientific.net/msf.1016.458

16043 Nguyen Xuan Thanh Tram, Kunio Ishikawa3, Tran Hoang Minh, David Benson and Kanji Tsuru Characterization of carbonate apatite derived from chicken bone and its in-vitro evaluation using MC3T3-E1 cells Mater. Res. Express 8 025401 2021 8:025401

16044 Masanobu KAMITAKAHARA, Airi ISHII, Hideaki MATSUBARA, Masakazu KAWASHITA, Maiko FURUYA, Hiroyasu KANETAKA Fabrication and evaluation of ascorbic acid phosphate-loaded spherical porous hydroxyapatite/octacalcium phosphate granules Journal of the Ceramic Society of Japan 2021 129:60-65 DOI: 10.2109/jcersj2.20170

16054 Murakami T, Matsugami D, Yoshida W, Imamura K, Bizenjima T, Seshima F, Saito A. Healing of Experimental Periodontal Defects Following Treatment with Fibroblast Growth Factor-2 and Deproteinized Bovine Bone Mineral Biomolecules 2021 11(6):805 PubMed ID: 34072351 DOI: 10.3390/biom11060805

16274 Aonuma F, Higashi S, Tsuka S, Ohsumi T, Masaki C, Hosokawa R, Takeuchi H. Effect of aging on bone metabolism: the involvement of complement C1q J Prosthodont Res 2021 65(3):393-399 PubMed ID: 33116027 DOI: 10.2186/jpr.JPOR_2019_644

16328 Almeida Alves CF, Fialho L, Marques SM, Pires S, Rico P, Palacio C, Carvalho S. MC3T3-E1 cell response to microporous tantalum oxide surfaces enriched with Ca, P and Mg Mater Sci Eng C Mater Biol Appl 2021 112008 PubMed ID: 33947579 DOI: 10.1016/j.msec.2021.112008

16329 Valanezhad A, Odatsu T, Abe S, Watanabe I. Bone Formation Ability and Cell Viability Enhancement of MC3T3-E1 Cells by Ferrostatin-1 a Ferroptosis Inhibitor of Cancer Cells Int J Mol Sci 2021 22(22):12259 PubMed ID: 34830144 DOI: 10.3390/ijms222212259

16330 Ryoichi Sato, Yasuhiro Namura, Natsuko Tanabe, Mayu Sakai, Akihisa Utsu, Keiko Tomita, Naoto Suzuki, Mitsuru Motoyoshi Atmospheric Pressure Plasma Treatment with Nitrogen Induces Osteoblast Differentiation and Reduces iNOS and COX-2 Expressions Journal of Hard Tissue Biology 2021 30:131-136 DOI: 10.2485/jhtb.30.131

16331 Lee CG, Kim J, Yun SH, Hwang S, Jeon H, Park E, Jeong SY. Anti-Osteoporotic Effect of Morroniside on Osteoblast and Osteoclast Differentiation In Vitro and Ovariectomized Mice In Vivo Int J Mol Sci 2021 ;22(19):10642 PubMed ID: 34638983 DOI: 10.3390/ijms221910642

16333 Jarrar H, Çetin Altındal D, Gümüşderelioğlu M. Scaffold-based osteogenic dual delivery system with melatonin and BMP-2 releasing PLGA microparticles Int J Pharm 2021 600:120489 PubMed ID: 33744449 DOI: 10.1016/j.ijpharm.2021.120489

16334 Nishino K, Tamai K, Orita K, Hashimoto Y, Nakamura H. Heated Tobacco Products Impair Cell Viability, Osteoblastic Differentiation, and Bone Fracture-Healing J Bone Joint Surg Am 2021 103(21):2024-2031 PubMed ID: 34730563 DOI: 10.2106/JBJS.20.02227

16335 Pham DN, Hiromoto S, Yamazaki T, O M, Kobayashi E. Enhanced Corrosion Resistance and In Vitro Biocompatibility of Mg-Zn Alloys by Carbonate Apatite Coating ACS Appl Bio Mater 2021 4(9):6881-6892 PubMed ID: 35006988 DOI: 10.1021/acsabm.1c00594

16336 Safaee S, Valanezhad A, Nesabi M, Jafarnia S, Sano H, Shahabi S, Abe S, Watanabe I. Fabrication of bioactive glass coating on pure titanium by sol-dip method: Dental applications Dent Mater J 2021 40:949-956 PubMed ID: 33716277 DOI: 10.4012/dmj.2020-323

16337 Soner Cakmak Compressible polyglycolic acid-based nanofibrous matrices as a bone filler: fabrication, physicochemical characterisations, and biocompatibility evaluation Materials Technology 2021 1-12 DOI: 10.1080/10667857.2021.1959216

16339 Kazuhiro Saito, Masanori Hiratuka, Yoshinobu Manome, Kouki Fujioka, Yasuharu Ohgoe, Hiroshi Honda, Kenji Hirakuri Effects of zinc-containing diamond-like carbon coated splints on the healing of fractures in mice: A pilot study Diamond and Related Materials 2021 119:108574 DOI: 10.1016/j.diamond.2021.108574

16340 Raihan MM, Otsuka Y, Tsuchida K, Manonukul A, Ohnuma K, Miyashita Y. Damage evaluation of HAp-coated porous titanium foam in simulated body fluid based on compression fatigue behavior J Mech Behav Biomed Mater 2021 117:104383 PubMed ID: 33596530 DOI: 10.1016/j.jmbbm.2021.104383

16362 Fujimaki T, Ando T, Hata T, Takayama Y, Ohba T, Ichikawa J, Takiyama Y, Tatsuno R, Koyama K, Haro H. Exogenous parathyroid hormone attenuates ovariectomy-induced skeletal muscle weakness in vivo Bone 2021 151:116029. PubMed ID: 34111645 DOI: 10.1016/j.bone.2021.116029

16379 Katsuya SATO, Daiki OOMORI Development of vibration mechanical stimuli loading device for live cell fluorescence microscopy Journal of Biomechanical Science and Engineering 2021 DOI: 10.1299/jbse.21-00294

16382 Wandel MB, Bell CA, Yu J, Arno MC, Dreger NZ, Hsu YH, Pitto-Barry A, Worch JC, Dove AP, Becker ML. Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering Nat Commun 2021 12(1):446 PubMed ID: 33469013 DOI: 10.1038/s41467-020-20610-5

16383 Yamazaki M, Kawai M, Kinoshita S, Tachikawa K, Nakanishi T, Ozono K, Michigami T. Clonal osteoblastic cell lines with CRISPR/Cas9-mediated ablation of Pit1 or Pit2 show enhanced mineralization despite reduced osteogenic gene expression Bone 2021 151:116036 PubMed ID: 34118444 DOI: 10.1016/j.bone.2021.116036

16868 Xiang C, Tenkumo T, Ogawa T, Kanda Y, Nakamura K, Shirato M, Sokolova V, Epple M, Kamano Y, Egusa H, Sasaki K. Gene transfection achieved by utilizing antibacterial calcium phosphate nanoparticles for enhanced regenerative therapy Acta Biomater 2021 119:375-389 PubMed ID: 33166711 DOI: 10.1016/j.actbio.2020.11.003

16878 Shuhei Ugaji, Kumi Kimura, Yasuhiko Yamamoto, Seiichi Munesue, Ai Harashima, Takao Aikawa, Yasuhisa Yoshida, Tomo Hamada, Toshifumi Hikichi, Hidenori Matsubara, Hiroyuki Tsuchiya Pyridoxamine improves diabetes-evoked delayed bone repair in mice Journal of Translational Science 2021 7 DOI: 10.15761/jts.1000413

16970 Miho Tamai, Kenichi Harimoto, Noriyuki Nagaoka, Kumiko Yoshihara, Yasuhiro Yoshida, Yoh-ichi Tagawa Cell Adherence Competition between Osteoblasts and Fibroblasts on Various Materials Influences the Establishment of Osseointegration Archives of Clinical and Biomedical Research 2021 05 DOI: 10.26502/acbr.50170191

17414 Saito M, Chiba A, Sato T, Moriya T, Sukegawa J, Nakahata N. Tctex-1 augments G protein-coupled receptor-mediated Gs signaling by activating adenylyl cyclase J Pharmacol Sci 2021 145(1):150-154 PubMed ID: 33357773 DOI: 10.1016/j.jphs.2020.11.011

17415 Yamaguchi Y, Matsuno T, Miyazawa A, Hashimoto Y, Satomi T. Bioactivity Evaluation of Biphasic Hydroxyapatite Bone Substitutes Immersed and Grown with Supersaturated Calcium Phosphate Solution Materials (Basel) 2021 14(18):5143 PubMed ID: 34576367 DOI: 10.3390/ma14185143

17416 Toprak Ö, Topuz B, Monsef YA, Oto Ç, Orhan K, Karakeçili A. BMP-6 carrying metal organic framework-embedded in bioresorbable electrospun fibers for enhanced bone regeneration Mater Sci Eng C Mater Biol Appl 2021 120:111738 PubMed ID: 33545881 DOI: 10.1016/j.msec.2020.111738

17727 Takeno A, Kanazawa I, Tanaka KI, Notsu M, Kanasaki K, Oono T, Ogawa Y, Sugimoto T. High glucose promotes mineralization via bone morphogenetic protein 4-Smad signals in early stage of osteoblast differentiation Diabetol Int 2020 12(2):171-180 PubMed ID: 33786272 DOI: 10.1007/s13340-020-00463-5

17762 Shi R, Hayashi K, Bang LT, Ishikawa K. Effects of surface roughening and calcite coating of titanium on cell growth and differentiation J Biomater Appl 2020 34(7):917-927 PubMed ID: 31653183 DOI: 10.1177/0885328219883765

17764 Widyowati R, Sulistyowaty MI, Uyen NH, Sugimoto S, Yamano Y, Otsuka H, Matsunami K. New Methyl Threonolactones and Pyroglutamates of Spilanthes acmella (L.) L. and Their Bone Formation Activities Molecules 2020 25(11):2500 PubMed ID: 32481486 DOI: 10.3390/molecules25112500

19384 Le Thi B, Shi R, Long BD, Ramesh S, Xingling S, Sugiura Y, Ishikawa K. Biological responses of MC3T3-E1 on calcium carbonate coatings fabricated by hydrothermal reaction on titanium Biomed Mater 2020 15(3):035004 PubMed ID: 31914435 DOI: 10.1088/1748-605X/ab6939

11802 Wang L, Bai J, Wang Q, Ge G, Lin J, Xu N, Xu C, Xu Y, Wang Y, Geng D. Inhibition of protein phosphatase 2A attenuates titanium-particle induced suppression of bone formation. Int. J. Biol. Macromol 2020 142:142-151 PubMed ID: 31521663 DOI: 10.1016/j.ijbiomac.2019.09.084

11852 Mulati M, Kobayashi Y, Takahashi A, Numata H, Saito M, Hiraoka Y, Ochi H, Sato S, Ezura Y, Yuasa M, Hirai T, Yoshii T, Okawa A, Inose H. The long noncoding RNA Crnde regulates osteoblast proliferation through the Wnt/β-catenin signaling pathway in mice. Bone 2020 130:115076 PubMed ID: 31622775 DOI: 10.1016/j.bone.2019.115076

6952 Minamizaki T, Nakao Y, Irie Y, Ahmed F, Itoh S, Sarmin N, Yoshioka H, Nobukiyo A, Fujimoto C, Niida S, Sotomaru Y, Tanimoto K, Kozai K, Sugiyama T, Bonnelye E, Takei Y, Yoshiko Y. The matrix vesicle cargo miR-125b accumulates in the bone matrix, inhibiting bone resorption in mice. Commun Biol 2020 ;3(1):30 PubMed ID: 31949279 DOI: 10.1038/s42003-020-0754-2

11934 Pimentel ES, Brito-Pereira R, Marques-Almeida T, Ribeiro C, Vaz F, Lanceros-Mendez S, Cardoso VF. Tailoring Electrospun Poly(l-lactic acid) Nanofibers as Substrates for Microfluidic Applications. ACS Appl Mater Interfaces 2020 PubMed ID: 31808332 DOI: 10.1021/acsami.9b12461

11946 Miyaji H, Mayumi K, Miyata S, Nishida E, Shitomi K, Hamamoto A, Tanaka S, Akasaka T. Comparative biological assessments of endodontic root canal sealer containing surface pre-reacted glass-ionomer (S-PRG) filler or silica filler. Dent Mater J 2020 PubMed ID: 31776316 DOI: 10.4012/dmj.2019-029

12034 Gültan T, Çapkın Yurtsever M, Gumusderelioglu M. NaOH etched /boron- doped nanohydroxyapatite coated PEEK implants enhance the proliferation and differentiation of osteogenic cells. Biomed Mater 2020 PubMed ID: 32000154 DOI: 10.1088/1748-605X/ab7198

12037 Nakagawa F, Higashi S, Ando E, Ohsumi T, Watanabe S, Takeuchi H. Modification of TRPV4 activity by acetaminophen. Heliyon 2020 PubMed ID: 32051870 DOI: 10.1016/j.heliyon.2020.e03301

12070 Suzuki A, Sugiyama G, Ohyama Y, Kumamaru W, Yamada T, Mori Y. Regulation of NF-kB Signalling Through the PR55β-RelA Interaction in Osteoblasts. In Vivo 2020 PubMed ID: 32111759 DOI: 10.21873/invivo.11813

12118 Shimabukuro M, Tsutsumi Y, Nozaki K, Chen P, Yamada R, Ashida M, Doi H, Nagai A, Hanawa T. Investigation of antibacterial effect of copper introduced titanium surface by electrochemical treatment against facultative anaerobic bacteria. Dent Mater J 2020 PubMed ID: 32249235 DOI: 10.4012/dmj.2019-178

12120 Okusha Y, Eguchi T, Tran MT, Sogawa C, Yoshida K, Itagaki M, Taha EA, Ono K, Aoyama E, Okamura H, Kozaki KI, Calderwood SK, Takigawa M, Okamoto K. Extracellular Vesicles Enriched with Moonlighting Metalloproteinase Are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer. Cancers (Basel) 2020 PubMed ID: 32260433 DOI: 10.3390/cancers12040881

12139 Miona Miljković, Vesna Lazić, Slađana Davidović, Ana Milivojević, Jelena Papan, Margarida M. Fernandes, Senentxu Lanceros-Mendez, S. Phillip Ahrenkiel & Jovan M. Nedeljković Selective Antimicrobial Performance of Biosynthesized Silver Nanoparticles by Horsetail Extract Against E. coli Journal of Inorganic and Organometallic Polymers and Materials 2020 30:2598–2607 DOI: 10.1007/s10904-019-01402-x

12140 Peng Chen, Huihong Liu, Mitsuo Niinomi, Zenji Horita, Hidetoshi Fujii, Takao Hanawa Fatigue Property and Cytocompatibility of a Biomedical Co–Cr–Mo Alloy Subjected to a High Pressure Torsion and a Subsequent Short Time Annealing MATERIALS TRANSACTIONS 2020 DOI: 10.2320/matertrans.MT-M2019148

12147 Satoshi Migita, Tomoya Yamaguchi Initial Adhesion Behavior of Osteoblast on Titanium with Sub-Micron Scale Roughness Recent Progress in Materials 2020 DOI: 10.21926/rpm.2001003

12167 Thet ThetSwe, Khairul AnuarShariff, Hasmaliza Mohamad, Kunio Ishikawa, Koichiro Hayashi, Mohamad HafiziAbu Bakar Behavioural response of cells and bacteria on single and multiple doped Sr and Ag S53P4 sol-gel bioglass Ceramics International 2020 DOI: 10.1016/j.ceramint.2020.04.094

13025 Furihata T, Miyaji H, Nishida E, Kato A, Miyata S, Shitomi K, Mayumi K, Kanemoto Y, Sugaya T, Akasaka T. Bone forming ability of recombinant human collagen peptide granules applied with β-tricalcium phosphate fine particles. J Biomed Mater Res B Appl Biomater 2020 PubMed ID: 32386261 DOI: 10.1002/jbm.b.34632

13043 Inubushi T, Kosai A, Yanagisawa S, Chanbora C, Miyauchi M, Yamasaki S, Sugiyama E, Ishikado A, Makino T, Takata T. Bovine lactoferrin enhances osteogenesis through Smad2/3 and p38 MAPK activation. J Oral Biosci 2020 PubMed ID: 32464258 DOI: 10.1016/j.job.2020.05.001

13070 Santhakumar S, Oyane A, Nakamura M, Koga K, Miyata S, Muratsubaki K, Miyaji H. In situ precipitation of amorphous calcium phosphate nanoparticles within 3D porous collagen sponges for bone tissue engineering. Mater Sci Eng C Mater Biol Appl 2020 PubMed ID: 32806285 DOI: 10.1016/j.msec.2020.111194

13094 Huang Y, Xiao D, Huang S, Zhuang J, Zheng X, Chang Y, Yin D. Circular RNA YAP1 attenuates osteoporosis through up-regulation of YAP1 and activation of Wnt/β-catenin pathway. Biomed Pharmacother 2020 PubMed ID: 32768931 DOI: 10.1016/j.biopha.2020.110365

13100 Rajan ST, V V AT, Terada-Nakaishi M, Chen P, Hanawa T, Nandakumar AK, Subramanian B. Zirconium-based metallic glass and zirconia coatings to inhibit bone formation on titanium. Biomed Mater 2020 PubMed ID: 32615545 DOI: 10.1088/1748-605X/aba23a

13107 Kito H, Morihiro H, Sakakibara Y, Endo K, Kajikuri J, Suzuki T, Ohya S. Downregulation of the Ca²⁺-activated K⁺ channel K_Ca3.1 in mouse preosteoblast cells treated with vitamin D receptor agonist. Am J Physiol Cell Physiol 2020 PubMed ID: 32520608 DOI: 10.1152/ajpcell.00587.2019

13145 Lazić V, Živković LS, Sredojević D, Fernandes MM, Lanceros-Mendez S, Ahrenkiel SP, Nedeljković JM. Tuning Properties of Cerium Dioxide Nanoparticles by Surface Modification with Catecholate-type of Ligands. Langmuir 2020 PubMed ID: 32787065 DOI: 10.1021/acs.langmuir.0c01163

13165 Haraguchi T, Ayukawa Y, Shibata Y, Takeshita T, Atsuta I, Ogino Y, Yasunami N, Yamashita Y, Koyano K. Effect of Calcium Chloride Hydrothermal Treatment of Titanium on Protein, Cellular, and Bacterial Adhesion Properties. J Clin Med 2020 PubMed ID: 32823609 DOI: 10.3390/jcm9082627

13196 Kato S, Tanabe N, Nagao M, Sekino J, Tomita K, Sakai M, Abe K, Suzuki N, Ueda K. Glucose transporter 4 mediates LPS-induced IL-6 production in osteoblasts under high glucose conditions. J Oral Sci 2020 PubMed ID: 32863319 DOI: 10.2334/josnusd.20-0010

13219 Sugiura Y, Obika H, Horie M, Niitsu K, Makita Y. Aesthetic Silver-Doped Octacalcium Phosphate Powders Exhibiting Both Contact Antibacterial Ability and Low Cytotoxicity. ACS Omega 2020 PubMed ID: 33015459 DOI: 10.1021/acsomega.0c02868

13273 Natsume N, Yonezawa T, Woo JT, Teruya T. Effect of pinocembrin isolated from Alpinia zerumbet on osteoblast differentiation. Cytotechnology 2020 PubMed ID: 33029744 DOI: 10.1007/s10616-020-00427-2

13343 Yamabe Y, Kawagoe Y, Okuno K, Inoue M, Chikaoka K, Ueda D, Tajima Y, Yamada TK, Kakihara Y, Hara T, Sato T. Construction of an artificial system for ambrein biosynthesis and investigation of some biological activities of ambrein. Sci Rep 2020 PubMed ID: 33184314 DOI: 10.1038/s41598-020-76624-y

13357 Marques-Almeida T, Cardoso VF, Gama M, Lanceros-Mendez S, Ribeiro C. Patterned Piezoelectric Scaffolds for Osteogenic Differentiation. Int J Mol Sci 2020 PubMed ID: 33171761 DOI: 10.3390/ijms21218352

13360 Park E, Kim J, Jin HS, Choi CW, Choi TH, Choi S, Huh D, Jeong SY. Scopolin Attenuates Osteoporotic Bone Loss in Ovariectomized Mice. Nutrients 2020 PubMed ID: 33233714 DOI: 10.3390/nu12113565

13378 Carvalho EO, Ribeiro C, Correia DM, Botelho G, Lanceros-Mendez S. Biodegradable Hydrogels Loaded with Magnetically Responsive Microspheres as 2D and 3D Scaffolds. Nanomaterials (Basel) 2020 PubMed ID: 33287454 DOI: 10.3390/nano10122421

13406 Park E, Lee CG, Lim E, Hwang S, Yun SH, Kim J, Jeong H, Yong Y, Yun SH, Choi CW, Jin HS, Jeong SY. Osteoprotective Effects of Loganic Acid on Osteoblastic and Osteoclastic Cells and Osteoporosis-Induced Mice. Int J Mol Sci 2020 PubMed ID: 33379387 DOI: 10.3390/ijms22010233

13443 T. T. Swe, K. A. Shariff, A. F. M. Noor, K. Ishikawa, and M. Hasmaliza Effect of strontium doping on bone nodule formation of sol-gel derived bioglass AIP Conference Proceedings 2020 DOI: 10.1063/5.0015714

13446 Ahmed Monir, Abdel Basit Abd El-Aal, Mohamed Omar, Mahasen El-Shair, Taro Mukaibo3, Ryuji Hosokawa The Viability and Cytotoxic Effect of High Mobility Group Box Protein 1 on MC3T3-E1 Pre-osteoblast Cells: an In Vitro Study Zagazig Veterinary Journal 2020 DOI: 10.21608/zvjz.2020.27091.1106

13508 Tenkumo T, Ishiyama K, Prymak O, Nakamura K, Shirato M, Ogawa T, Miyashita M, Takahashi M, Epple M, Kanno T, Sasaki K. Bactericidal activity and recovery effect of hydroxyl radicals generated by ultraviolet irradiation and silver ion application on an infected titanium surface Sci Rep 2020 10(1):855 PubMed ID: 32444858 DOI: 10.1038/s41598-020-65411-4

13536 Amaro L, Correia DM, Martins PM, Botelho G, Carabineiro SAC, Ribeiro C, Lanceros-Mendez S. Morphology Dependence Degradation of Electro- and Magnetoactive Poly(3-hydroxybutyrate-co-hydroxyvalerate) for Tissue Engineering Applications Polymers (Basel) 2020 12(4):953 PubMed ID: 32325963 DOI: 10.3390/polym12040953

13546 Wang Q, Ge G, Liang X, Bai J, Wang W, Zhang W, Zheng K, Yang S, Wei M, Yang H, Xu Y, Liu B, Geng D. Punicalagin ameliorates wear-particle-induced inflammatory bone destruction by bi-directional regulation of osteoblastic formation and osteoclastic resorption Biomater Sci 2020 8(18):5157-5171 PubMed ID: 32840273 DOI: 10.1039/d0bm00718h

13636 Inoue A, Nakao-Kuroishi K, Kometani-Gunjigake K, Mizuhara M, Shirakawa T, Ito-Sago M, Yasuda K, Nakatomi M, Matsubara T, Tada-Shigeyama Y, Morikawa K, Kokabu S, Kawamoto T. VNUT/SLC17A9, a vesicular nucleotide transporter, regulates osteoblast differentiation FEBS Open Bio 2020 10(8):1612-1623. PubMed ID: 32592329 DOI: 10.1002/2211-5463.12918

13638 Yamada S, Motozuka S, Tagaya M. Synthesis of nanostructured silica/hydroxyapatite hybrid particles containing amphiphilic triblock copolymer for effectively controlling hydration layer structures with cytocompatibility J Mater Chem B7. 2020 8(7):1524-153 PubMed ID: 32003398 DOI: 10.1039/c9tb02534k

13649 Suzuki R, Fujiwara Y, Saito M, Arakawa S, Shirakawa JI, Yamanaka M, Komohara Y, Marumo K, Nagai R. Intracellular Accumulation of Advanced Glycation End Products Induces Osteoblast Apoptosis Via Endoplasmic Reticulum Stress J Bone Miner Res 2020 35(10):1992-2003 PubMed ID: 32427355 DOI: 10.1002/jbmr.4053

13839 Kako Yamasaki, Mitsuhiro Hirano, Shiori komai, Hiroki Taniho, Naofumi Ohtsu Cell responses on Ni-free anodized layer of NiTi alloy with various surface morphologies Applied Surface Science 2020 531:30 DOI: 10.1016/j.apsusc.2020.147351

13923 Raju R, Oshima M, Inoue M, Morita T, Huijiao Y, Waskitho A, Baba O, Inoue M, Matsuka Y. Three-dimensional periodontal tissue regeneration using a bone-ligament complex cell sheet Sci Rep 2020 10(1):1656 PubMed ID: 32015383 DOI: 10.1038/s41598-020-58222-0

13933 Suzuki H, Ohshima N, Tatei K, Taniguchi T, Sato S, Izumi T. The role of autonomously secreted PGE 2 and its autocrine/paracrine effect on bone matrix mineralization at the different stages of differentiating MC3T3-E1 cells Biochem Biophys Res Commun 2020 524(4):929-935 PubMed ID: 32059846 DOI: 10.1016/j.bbrc.2020.01.120

13938 Widyowati, Retno; Ekasari, Wiwied; Purwitasari, Neny Amine Derivative from the Aerial Part of Spilanthes acmella Murr. and their Alkaline Phosphatase Activity The Natural Products Journal 2020 10:571-577 DOI: 10.2174/2210315509666190807161413

13943 Yashiro M, Ohya M, Mima T, Nakashima Y, Kawakami K, Yamamoto S, Kobayashi S, Yano T, Tanaka Y, Sonou T, Tatsuta K, Negi S, Shigematsu T. Active vitamin D and vitamin D analogs stimulate fibroblast growth factor 23 production in osteocyte-like cells via the vitamin D receptor J Pharm Biomed Anal 2020 182:113139 PubMed ID: 32045827 DOI: 10.1016/j.jpba.2020.113139

14181 Tsubaki M, Seki S, Takeda T, Chihara A, Arai Y, Morii Y, Imano M, Satou T, Shimomura K, Nishida S. The HGF/Met/NF-κB Pathway Regulates RANKL Expression in Osteoblasts and Bone Marrow Stromal Cells Int J Mol Sci 2020 21(21):7905 PubMed ID: 33114380 DOI: 10.3390/ijms21217905

14278 Castro N, Fernandes MM, Ribeiro C, Correia V, Minguez R, Lanceros-Méndez S. Magnetic Bioreactor for Magneto-, Mechano- and Electroactive Tissue Engineering Strategies Sensors (Basel) 2020 20(12):3340 PubMed ID: 32545551 DOI: 10.3390/s20123340

14502 Guo J, Wang Z, Weng Y, Yuan H, Yoshida K, Ikegame M, Uchibe K, Kamioka H, Ochiai K, Okamura H, Qiu L. N-(3-oxododecanoyl)-homoserine lactone regulates osteoblast apoptosis and differentiation by mediating intracellular calcium Cell Signal 2020 75:109740 PubMed ID: 32818672 DOI: 10.1016/j.cellsig.2020.109740

14845 Rui Shi, Koichiro Hayashi, Kunio Ishikawa Rapid Osseointegration Bestowed by Carbonate Apatite Coating of Rough Titanium Advanced Materials Interfaces 2020 7:2000636 DOI: 10.1002/admi.202000636

14870 A. Reizabal, R. Brito-Pereira, M.M. Fernandes, N. Castro, V. Correia, C. Ribeiro, C.M. Costa, L. Perez, J.L. Vilas, S. Lanceros-Méndez Silk fibroin magnetoactive nanocomposite films and membranes for dynamic bone tissue engineering strategies Materialia 2020 12:100709 DOI: 10.1016/j.mtla.2020.100709

16376 Natsume N, Ozaki K, Nakajima D, Yokoshima S, Teruya T. Structure-Activity Relationship Study of Majusculamides A and B and Their Analogues on Osteogenic Activity J Nat Prod 2020 83(8):2477-2482 PubMed ID: 32786886 DOI: 10.1021/acs.jnatprod.0c00441

16377 Burger D, Beaumont M, Rosenau T, Tamada Y. Porous Silk Fibroin/Cellulose Hydrogels for Bone Tissue Engineering via a Novel Combined Process Based on Sequential Regeneration and Porogen Leaching Molecules 2020 25(21):5097 PubMed ID: 33153040 DOI: 10.3390/molecules25215097

16378 Daisuke Isaji, Takehiro Watanabe, Takahiro Takahashi, Hiroki Sato, Hiroshi Nakada, Yasuhiro Tanimoto, Megumi Fuse, Suguru Kimoto, Yasuhiko Kawai Examination of Optimal Concentrations of Poly (Lactic-co-glycolic Acid) in Hexafluoroisopropyl Alcohol for Guided Bone Regeneration Membrane Prepared by Electrospinning International Journal of Oral-Medical Sciences 2020 18:239-247 DOI: 10.5466/ijoms.18.239

16380 Tsuji K, Kimura S, Tateda K, Takahashi H. Does Vitamin D3 Prevent the Inhibitory Effect of Vancomycin on Osteoblasts? Clin Orthop Relat Res 2020 478(2):420-433 PubMed ID: 31794484 DOI: 10.1097/CORR.0000000000001060

16381 Daisuke Isaji, Takehiro Watanabe, Takahiro Takahashi, Hiroki Sato, Hiroshi Nakada, Yasuhiro Tanimoto, Megumi Fuse, Suguru Kimoto, Yasuhiko Kawai Preparation and Evaluation of a Poly(Lactic-co-glycolic Acid)Membrane Containing β-TCP International Journal of Oral-Medical Sciences 2020 18:248-256 DOI: 10.5466/ijoms.18.248

16930 Miki H, Okito A, Akiyama M, Ono T, Tachikawa N, Nakahama KI. Genetic and epigenetic regulation of osteopontin by cyclic adenosine 3' 5'-monophosphate in osteoblasts Gene 2020 763:145059 PubMed ID: 32858177 DOI: 10.1016/j.gene.2020.145059

22190 Hiromoto S, Itoh S, Noda N, Yamazaki T, Katayama H, Akashi T. Osteoclast and osteoblast responsive carbonate apatite coatings for biodegradable magnesium alloys Sci Technol Adv Mater 2020 21(1):346-358 PubMed ID: 32939160 DOI: 10.1080/14686996.2020.1761237

22191 Kato K, Lee S, Nagata F. Preparation of Protein-Peptide-Calcium Phosphate Composites for Controlled Protein Release Molecules 2020 25(10):2312 PubMed ID: 32423135 DOI: 10.3390/molecules25102312

22367 Hoshikawa S, Shimizu K, Watahiki A, Chiba M, Saito K, Wei W, Fukumoto S, Inuzuka H. Phosphorylation-dependent osterix degradation negatively regulates osteoblast differentiation FASEB J 2020 34(11):14930-14945 PubMed ID: 32931083 DOI: 10.1096/fj.202001340R

17765 Díaz E, Blanca Valle MLSGALG, Ribeiro S, Lanceros-Mendez S, Barandiarán JM. 3D Cytocompatible Composites of PCL/magnetite Materials (Basel) 2019 12(23):3843 PubMed ID: 31766520 DOI: 10.3390/ma12233843

11232 Tsukune N, Naito M, Ohashi A, Ninomiya T, Sato S, Takahashi T. Forced expression of mouse progerin attenuates the osteoblast differentiation interrupting β-catenin signal pathway in vitro. Cell Tissue Res. 2019 PubMed ID: 30284086 DOI: 10.1007/s00441-018-2930-y

11258 Nguyen HT, Ono M, Oida Y, Hara ES, Komori T, Akiyama K, Nguyen HTT, Aung KT, Pham HT, Tosa I, Takarada T, Matsuo K, Mizoguchi T, Oohashi T, Kuboki T. Bone Marrow Cells Inhibit BMP-2-Induced Osteoblast Activity in the Marrow Environment. J. Bone Miner. Res. 2019 PubMed ID: 30352125 DOI: 10.1002/jbmr.3598

11302 Baba TT, Terashima T, Oida S. Liver-type of tissue non-specific alkaline phosphatase is induced during mouse bone and tooth cell differentiation. Arch. Oral Biol. 2019 PubMed ID: 30439569 DOI: 10.1016/j.archoralbio.2018.10.036

11486 Abdelrhman Y, Gepreel MA, Kobayashi S, Okano S, Okamoto T. Biocompatibility of new low-cost (α + β)-type Ti-Mo-Fe alloys for long-term implantation. Mater Sci Eng C Mater Biol Appl 2019 PubMed ID: 30889729 DOI: 10.1016/j.msec.2019.01.133

11445 Kuriya K, Nishio M, Wada S, Katsuzaki H, Nishise M, Okamoto H, Umekawa H. Antiosteoporotic Effects of Acer palmatum Extract on Osteoclastogenesis and Osteoblastogenesis. J Med Food 2019 PubMed ID: 30785809 DOI: 10.1089/jmf.2018.4243

11462 Sasaki JI, Kiba W, Abe GL, Katata C, Hashimoto M, Kitagawa H, Imazato S. Fabrication of strontium-releasable inorganic cement by incorporation of bioactive glass. Dent Mater 2019 PubMed ID: 30827799 DOI: 10.1016/j.dental.2019.02.019

11484 Kusuyama J, Amir MS, Albertson BG, Bandow K, Ohnishi T, Nakamura T, Noguchi K, Shima K, Semba I, Matsuguchi T. JNK inactivation suppresses osteogenic differentiation, but robustly induces osteopontin expression in osteoblasts through the induction of inhibitor of DNA binding 4 (Id4). FASEB J. 2019 PubMed ID: 30884976 DOI: 10.1096/fj.201802465R

11485 Nakamura K, Shirato M, Tenkumo T, Kanno T, Westerlund A, Örtengren U, Sasaki K, Niwano Y. Hydroxyl radicals generated by hydrogen peroxide photolysis recondition biofilm-contaminated titanium surfaces for subsequent osteoblastic cell proliferation. Sci Rep 2019 PubMed ID: 30886168 DOI: 10.1038/s41598-019-41126-z

4575 Park E, Kim J, Kim MC, Yeo S, Kim J, Park S, Jo M, Choi CW, Jin HS, Lee SW, Li WY, Lee JW, Park JH, Huh D, Jeong SY. Anti-Osteoporotic Effects of Kukoamine B Isolated from Lycii Radicis Cortex Extract on Osteoblast and Osteoclast Cells and Ovariectomized Osteoporosis Model Mice. Int J Mol Sci 2019 20(11). pii: E2784 PubMed ID: 31174394 DOI: 10.3390/ijms20112784

11495 Tanaka K, Kondo H, Hamamura K, Togari A. Systemic administration of low-dose naltrexone increases bone mass due to blockade of opioid growth factor receptor signaling in mice osteoblasts. Life Sci. 2019 PubMed ID: 30930116 DOI: 10.1016/j.lfs.2019.03.069

11535 Suzuki H, Tatei K, Ohshima N, Sato S, Izumi T. Regulation of MC3T3-E1 differentiation by actin cytoskeleton through lipid mediators reflecting the cell differentiation stage. Biochem. Biophys. Res. Commun. 2019 PubMed ID: 31047639 DOI: 10.1016/j.bbrc.2019.04.093

11543 Oki Y, Kirita K, Ohta S, Ohba S, Horiguchi I, Sakai Y, Ito T. Switching of Cell Proliferation/Differentiation in Thiol-Maleimide Clickable Microcapsules Triggered by in Situ Conjugation of Biomimetic Peptides. Biomacromolecules 2019 PubMed ID: 31059241 DOI: 10.1021/acs.biomac.9b00333

11562 Akatsu Y, Takahashi N, Yoshimatsu Y, Kimuro S, Muramatsu T, Katsura A, Maishi N, Suzuki HI, Inazawa J, Hida K, Miyazono K, Watabe T. Fibroblast growth factor signals regulate transforming growth factor-β-induced endothelial-to-myofibroblast transition of tumor endothelial cells via Elk1. Mol Oncol 2019 PubMed ID: 31094056 DOI: 10.1002/1878-0261.12504

11599 Yamada M, Valanezhad A, Egoshi T, Tashima Y, Watanabe I, Murata H. Bioactive glass coating on zirconia by vacuum sol-dipping method. Dent Mater J 2019 PubMed ID: 31189794 DOI: 10.4012/dmj.2018-222

11601 Hermenegildo B, Ribeiro C, Pérez-Álvarez L, Vilas JL, Learmonth DA, Sousa RA, Martins P, Lanceros-Méndez S. Hydrogel-based magnetoelectric microenvironments for tissue stimulation. Colloids Surf B Biointerfaces 2019 PubMed ID: 31382332 DOI: 10.1016/j.colsurfb.2019.06.023

11615 He T, Shen H, Zhu J, Zhu Y, He Y, Li Z, Lu H. Geniposide attenuates cadmium‑induced oxidative stress injury via Nrf2 signaling in osteoblasts. Mol Med Rep 2019 PubMed ID: 31257486 DOI: 10.3892/mmr.2019.10396

11640 Tsutsumi K, Sasase T. Cellular calcification induced by inorganic polyphosphate involves ATP depletion and opening of the mitochondrial permeability transition pore (mPTP). FEBS Open Bio 2019 PubMed ID: 31325410 DOI: 10.1002/2211-5463.12703

11660 Damla Çetin Altındal, Menemşe Gümüşderelioğlu Dual-functional melatonin releasing device loaded with PLGA microparticles and cyclodextrin inclusion complex for osteosarcoma therapy Journal of Drug Delivery Science and Technology 2019 DOI: 10.1016/j.jddst.2019.05.027

11662 Vincent Irawan,Yusuke Sasaki, Toshiyuki Ikoma Fabrication of continuous apatite-graded collagen sponges via electrolysis method Journal of Materials Chemistry B 2019 DOI: 10.1039/C9TB00791A

11665 MA Huq, MH Siddiqi, YJ Kim, S Akter, DC Yang Stimulating effect of fermented ginseng leaf saponin on the differentiation and mineralization of murine osteoblastic MC3T3-E1 cells Bangladesh J. Sci. Ind. 2019 DOI: 10.3329/bjsir.v54i2.41671

11672 Junfeng Wang, Shukei Sugita, Tatsuo Michiue, Takashi Tsuboi, Tetsuya Kitaguchi, Takeo Matsumoto A novel FRET analysis method for tension dynamics in a single actin stress fiber: Application to MC3T3-E1 cells during movement on a substrate Journal of Biorheology 2019 DOI: 10.17106/jbr.33.21

11689 Murat Şimşek, Sevcan Dalkıranoğlu Aldemir, Menemşe Gümüşderelioğlu Anticellular PEO coatings on titanium surfaces by sequential electrospinning and crosslinking processes Emergent Materials 2019 DOI: 10.1007/s42247-019-00040-w

11697 Menglin Zhu, Jing Gu, Lili He, Faraz Khan Mahar, Icksoo Kim, Kai Wei Fabrication and Osteoblastic Adhesion Behavior of Regenerated Silk Fibroin/PLLA Nanofibrous Scaffold by Double Syringe Electrospinning Fibers and Polymers 2019 DOI: 10.1007/s12221-019-1188-7

11707 Masaya Shimabukuro, Yusuke Tsutsumi, Kosuke Nozaki, Peng Chen, Risa Yamada, Maki Ashida, Hisashi Doi, Akiko Nagai, Takao Hanawa Chemical and Biological Roles of Zinc in a Porous Titanium Dioxide Layer Formed by Micro-Arc Oxidation Coatings 2019 DOI: 10.3390/coatings9110705

11713 Tsuyoshi Narimiya, Hiroyuki Kanzaki, Yuki Yamaguchi, Satoshi Wada, Yuta Katsumata, Ken Tanaka, Hiroshi Tomonari Nrf2 activation in osteoblasts suppresses osteoclastogenesis via inhibiting IL-6 expression Bone Reports 2019 PubMed ID: 31763378 DOI: 10.1016/j.bonr.2019.100228

11731 Eiraku N, Chiba N, Nakamura T, Amir MS, Seong CH, Ohnishi T, Kusuyama J, Noguchi K, Matsuguchi T. BMP9 directly induces rapid GSK3-β phosphorylation in a Wnt-independent manner through class I PI3K-Akt axis in osteoblasts. FASEB J. 2019 PubMed ID: 31365832 DOI: 10.1096/fj.201900733RR

11750 Karakeçili A, Topuz B, Korpayev S, Erdek M. Metal-organic frameworks for on-demand pH controlled delivery of vancomycin from chitosan scaffolds. Mater Sci Eng C Mater Biol Appl 2019 PubMed ID: 31546383 DOI: 10.1016/j.msec.2019.110098

11764 Nakao N, Maki K, Mofrad MRK, Adachi T. Talin is required to increase stiffness of focal molecular complex in its early formation process. Biochem. Biophys. Res. Commun. 2019 PubMed ID: 31451222 DOI: 10.1016/j.bbrc.2019.08.091

11765 Abe T, Sato T, Yoda T, Hoshi K. The period circadian clock 2 gene responds to glucocorticoids and regulates osteogenic capacity. Regen Ther 2019 PubMed ID: 31489343 DOI: 10.1016/j.reth.2019.07.006

11813 Böhm AM, Dirckx N, Tower RJ, Peredo N, Vanuytven S, Theunis K, Nefyodova E, Cardoen R, Lindner V, Voet T, Van Hul M, Maes C. Activation of Skeletal Stem and Progenitor Cells for Bone Regeneration Is Driven by PDGFRβ Signaling. Dev. Cell 2019 PubMed ID: 31543445 DOI: 10.1016/j.devcel.2019.08.013

11856 Hamaya E, Fujisawa T, Tamura M. Osteoadherin serves roles in the regulation of apoptosis and growth in MC3T3‑E1 osteoblast cells. Int. J. Mol. Med. 2019 PubMed ID: 31638177 DOI: 10.3892/ijmm.2019.4376

6898 Sato K, Matsubara O, Hase E, Minamikawa T, Yasui T. Quantitative in situ time-series evaluation of osteoblastic collagen synthesis under cyclic strain using second-harmonic-generation microscopy. J Biomed Opt 2019 24(3):1-8 PubMed ID: 30635995 DOI: 10.1117/1.JBO.24.3.031019

6930 Kojima, C., Watanabe, K., Murata, H. et al Controlled release of DNA from zinc and magnesium ion-doped hydroxyapatites. Res Chem Intermed 2019 45:23–32 DOI: 10.1007/s11164-018-3626-3

6935 SOO LENG LEE*, ZAINAL ARIFF ABDUL RAHMAN, HIDETSUGU TSUJIGIWA, MEI HAMADA, KIYOFUMI TAKABATAKE, KEISUKE NAKANO, HITOSHI NAGATSUKA & CHONG HUAT SIAR An in vitro Three-Dimensional Co-Culture System for Ameloblastoma Modelling Sains Malaysiana 2019 48(8):1697–1706 DOI: 10.17576/jsm-2019-4808-15

6944 Yo S, Hamamura K, Mishima Y, Hamajima K, Mori H, Furukawa K, Kondo H, Tanaka K, Sato T, Miyazawa K, Goto S, Togari A. Deficiency of GD3 Synthase in Mice Resulting in the Attenuation of Bone Loss with Aging. Int J Mol Sci 2019 20(11):2825 PubMed ID: 31185614 DOI: 10.3390/ijms20112825

8028 Machino R, Matsumoto K, Taniguchi D, Tsuchiya T, Takeoka Y, Taura Y, Moriyama M, Tetsuo T, Oyama S, Takagi K, Miyazaki T, Hatachi G, Doi R, Shimoyama K, Matsuo N, Yamasaki N, Nakayama K, Nagayasu T Replacement of Rat Tracheas by Layered, Trachea-Like, Scaffold-Free Structures of Human Cells Using a Bio-3D Printing System. Adv Healthc Mater 2019 8(7):e1800983 PubMed ID: 30632706 DOI: 10.1002/adhm.201800983

9889 Ki Chan, James Kit-Hon Tsoi, On-Ki Wu, Madeline Jun-Yu Yon, Ricky Wing-Kit Wong Mechanical and Biological Evaluations of Novel Electrospun PLLA Composite Scaffolds Doped With Oxide Ceramics J Mech Behav Biomed Mater . 2019 Sep;97:229-237. 2019 97:229-237. PubMed ID: 31132659 DOI: 10.1016/j.jmbbm.2019.05.024

9891 Shoichi Moroi, Takayuki Miura, Takashi Tamura, Xi Zhang, Kazuhiro Ura, Yasuaki Takagi Self-assembled Collagen Fibrils From the Swim Bladder of Bester Sturgeon Enable Alignment of MC3T3-E1 Cells and Enhance Osteogenic Differentiation Mater Sci Eng C Mater Biol Appl 2019 104:109925 PubMed ID: 31500066 DOI: 10.1016/j.msec.2019.109925

9894 Hiraku Suzuki, Kazuaki Tatei, Noriyasu Ohshima, Seiichi Sato, Takashi Izumi Extracellular matrix mineralization in the mouse osteoblast-like cell line MC3T3-E1 is regulated by actin cytoskeleton reorganization and non-protein molecules secreted from the cells themselves bioRxiv 2019 DOI: 10.1101/551531

9895 Tae Yoon Park, Yun Jung Yang, Dong-Heon Ha, Dong-Woo Cho, Hyung Joon Cha Marine-derived Natural Polymer-Based Bioprinting Ink for Biocompatible, Durable, and Controllable 3D Constructs Biofabrication 2019 11(3):035001 PubMed ID: 30831562 DOI: 10.1088/1758-5090/ab0c6f

10369 Masaya Shimabukuro, Haruka Ito, Yusuke Tsutsumi, Kosuke Nozaki, Peng Chen, Risa Yamada, Maki Ashida, Akiko Nagai and Takao Hanawa The Effects of Various Metallic Surfaces on Cellular and Bacterial Adhesion Metals 2019 9(11):1145 DOI: 10.3390/met9111145

10451 Satoshi Migita, Kosuke Sakashita, Suyalatu Osteoblast compatibility of 3D printed Co–Cr–Mo alloys with different building direction Biosurface and Biotribology 2019 5:67 DOI: 10.1049/bsbt.2018.0043

10452 Masakazu INUBUSHI, Takuya NOTOMI, Tadashige NOZAKI Retinoic acid promotes migration of MC3T3‐E1 osteoblast‐like cells via RARα signaling‐mediated upregulation of profilin‐1 expression Journal of Osaka Dental University 2019 53:149-156 DOI: 10.18905/jodu.53.2_149

10458 M. Iwasaka Deformation of cellular components of bone forming cells when exposed to a magnetic field AIP Advances 2019 9 DOI: 10.1063/1.5079635

10467 Takuya NOTOMI, Masakazu INUBUSHI, Tadashige NOZAKI Synaptotagmin VII affects RANKL‐lysosomal vesicle fusion to the cell membrane in osteoblast‐like cells Journal of Osaka Dental University 2019 53:141-147 DOI: 10.18905/jodu.53.2_141

10653 Teresa Marques-AlmeidaTeresa Marques-Almeida CF-UM-UP, Centro de Física das Universidades do Minho e Porto, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal More by Teresa Marques-Almeida , Vanessa F. Cardoso*, Sylvie Ribeiro, Francisco M. Gama, Clarisse Ribeiro*, and Senentxu Lanceros-Mendez Tuning Myoblast and Preosteoblast Cell Adhesion Site, Orientation, and Elongation through Electroactive Micropatterned Scaffolds ACS Appl. Bio Mater 2019 2:1591–1602 PubMed ID: 35026893 DOI: 10.1021/acsabm.9b00020

10654 Takahito MIKI, Tomonori MATSUNO,Yoshiya HASHIMOTO, Akiko MIYAKE and Takafumi SATOMI In Vitro and In Vivo Evaluation of Titanium Surface Modification for Biological Aging by Electrolytic Reducing Ionic Water Appl Sci 2019 9(4);713 DOI: 10.3390/app9040713

11892 Fernandes MM, Correia DM, Ribeiro C, Castro N, Correia V, Lanceros-Mendez S. Bioinspired Three-Dimensional Magnetoactive Scaffolds for Bone Tissue Engineering. ACS Appl Mater Interfaces 2019 PubMed ID: 31682095 DOI: 10.1021/acsami.9b14001

11895 Park E, Kim J, Yeo S, Lim E, Choi CW, Choi S, Li WY, Lee JW, Park JH, Huh D, Jeong SY. Anti-Osteoporotic Effects of Combined Extract of Lycii Radicis Cortex and Achyranthes japonica in Osteoblast and Osteoclast Cells and Ovariectomized Mice. Nutrients 2019 PubMed ID: 31717518 DOI: 10.3390/nu11112716

11950 Gümüşderelioğlu M, Sunal E, Tolga Demirtaş T, Kiremitçi AS. Chitosan-based double-faced barrier membrane coated with functional nanostructures and loaded with BMP-6. J Mater Sci Mater Med 2019 PubMed ID: 31832785 DOI: 10.1007/s10856-019-6331-x

11066 Masaya ShimabukuroMasaya, Yusuke Tsutsumi, Risa Yamada, Maki Ashida, Peng Chen, Hisashi Doi, Kosuke Nozaki, Akiko Nagai, and Takao Hanawa Investigation of Realizing Both Antibacterial Property and Osteogenic Cell Compatibility on Titanium Surface by Simple Electrochemical Treatment ACS Biomater Sci Eng 2019 5623–5630 PubMed ID: 33405692 DOI: 10.1021/acsbiomaterials.8b01058

11069 Gülseren Irmak, Tuǧrul Tolga Demirtaş, and Menemşe Gümüşderelioǧlu Highly Methacrylated Gelatin Bioink for Bone Tissue Engineering ACS Biomater Sci Eng 2019 831–845 PubMed ID: 33405843 DOI: 10.1021/acsbiomaterials.8b00778

11469 E. Çatıker ORCID Icon,E. Konuk,T. Gültan &M. Gümüşderelioğlu Enhancement of scaffolding properties for poly(3-hydroxybutyrate): blending with poly-β-alanine and wet electrospinning International Journal of Polymeric Materials and Polymeric Biomaterials 2019 338-349 DOI: 10.1080/00914037.2018.1552862

12507 Kazi GAS, Rahman KA, Farahat M, Matsumoto T. Fabrication of single gel with different mechanical stiffness using three-dimensional mold J Biomed Mater Res A 2019 107(1):6-11 PubMed ID: 29781218 DOI: 10.1002/jbm.a.36455

12508 Liu H, Yang M, Wu G, Yang L, Cao Y, Liu C, Tan Z, Jin Y, Guo J, Zhu L. Effects of different oxygen concentrations on the proliferation, survival, migration, and osteogenic differentiation of MC3T3-E1 cells Connect Tissue Res 2019 60(3):240-253 PubMed ID: 29916278 DOI: 10.1080/03008207.2018.1487413

12509 Ishida H, Haniu H, Takeuchi A, Ueda K, Sano M, Tanaka M, Takizawa T, Sobajima A, Kamanaka T, Saito N. In Vitro and In Vivo Evaluation of Starfish Bone-Derived β-Tricalcium Phosphate as a Bone Substitute Material Materials (Basel) 2019 12(11):1881 PubMed ID: 31212709 DOI: 10.3390/ma12111881

12510 Morakul S, Otsuka Y, Ohnuma K, Tagaya M, Motozuka S, Miyashita Y, Mutoh Y. Enhancement effect on antibacterial property of gray titania coating by plasma-sprayed hydroxyapatite-amino acid complexes during irradiation with visible light Heliyon 2019 5(8):e02207 PubMed ID: 31517079 DOI: 10.1016/j.heliyon.2019.e02207

12511 Miyamoto H, Sawaji Y, Iwaki T, Masaoka T, Fukada E, Date M, Yamamoto K. Intermittent pulsed electromagnetic field stimulation activates the mTOR pathway and stimulates the proliferation of osteoblast-like cells Bioelectromagnetics 2019 40(6):412-421 PubMed ID: 31338867 DOI: 10.1002/bem.22207

12512 Cao NQ, Le HM, Pham KM, Nguyen NV, Hiromoto S, Kobayashi E. In Vitro Corrosion and Cell Response of Hydroxyapatite Coated Mg Matrix in Situ Composites for Biodegradable Material Applications Materials (Basel) 2019 12(21):3474 PubMed ID: 31652717 DOI: 10.3390/ma12213474

12513 Takahashi A, Morita T, Murata K, Minowa E, Jahan A, Saito M, Tanimura A. Effects of full-length human amelogenin on the differentiation of dental epithelial cells and osteoblastic cells Arch Oral Biol 2019 107:104479 PubMed ID: 31330473 DOI: 10.1016/j.archoralbio.2019.07.004

12514 Isoshima K, Ueno T, Arai Y, Saito H, Chen P, Tsutsumi Y, Hanawa T, Wakabayashi N. The change of surface charge by lithium ion coating enhances protein adsorption on titanium J Mech Behav Biomed Mater 2019 100:103393 PubMed ID: 31450101 DOI: 10.1016/j.jmbbm.2019.103393

12515 Baba TT, Miyazaki T, Ohara-Nemoto Y, Nemoto TK. Suppressive effects of N-bisphosphonate in osteoblastic cells mitigated by non-N-bisphosphonate but not by sodium-dependent phosphate cotransporter inhibitor Cell Biochem Funct 2019 37(6):400-407 PubMed ID: 31328801 DOI: 10.1002/cbf.3418

12592 Takeno A, Kanazawa I, Tanaka KI, Notsu M, Sugimoto T. Phloretin Suppresses Bone Morphogenetic Protein-2-Induced Osteoblastogenesis and Mineralization via Inhibition of Phosphatidylinositol 3-kinases/Akt Pathway Int J Mol Sci 2019 20(10):2481 PubMed ID: 31137461 DOI: 10.3390/ijms20102481

12978 Kojima C, Narita Y, Nakajima Y, Morimoto N, Yoshikawa T, Takahashi N, Handa A, Waku T, Tanaka N. Modulation of Cell Adhesion and Differentiation on Collagen Gels by the Addition of the Ovalbumin Secretory Signal Peptide. ACS Biomater Sci Eng 2019 PubMed ID: 33405701 DOI: 10.1021/acsbiomaterials.8b01505

14878 Toshihiko Shiraishi, Kota Nagai A Study of Mechanosensing of an Osteoblast at Focal Adhesions Under Cyclic Strain Using Magnetic Micropillars Biomedical and Biotechnology Engineering 2019 3 DOI: 10.1115/imece2019-11132

14886 Yoneda M, Suzuki H, Hatano N, Nakano S, Muraki Y, Miyazawa K, Goto S, Muraki K. PIEZO1 and TRPV4, which Are Distinct Mechano-Sensors in the Osteoblastic MC3T3-E1 Cells, Modify Cell-Proliferation Int J Mol Sci 2019 20(19):4960 PubMed ID: 31597314 DOI: 10.3390/ijms20194960

18198 Cui X, Murakami T, Tamura Y, Aoki K, Hoshino Y, Miura Y. Bacterial Inhibition and Osteoblast Adhesion on Ti Alloy Surfaces Modified by Poly(PEGMA- r-Phosmer) Coating ACS Appl Mater Interfaces 2018 10(28):23674-23681 PubMed ID: 29944334 DOI: 10.1021/acsami.8b07757

10429 Nakatsu Y, Nakagawa F, Higashi S, Ohsumi T, Shiiba S, Watanabe S, Takeuchi H. Effect of acetaminophen on osteoblastic differentiation and migration of MC3T3-E1 cells. Pharmacol Rep 2018 70:29-36 PubMed ID: 29306760 DOI: 10.1016/j.pharep.2017.07.006

10469 Matsuyama A, Higashi S, Tanizaki S, Morotomi T, Washio A, Ohsumi T, Kitamura C, Takeuchi H. Celecoxib inhibits osteoblast differentiation independent of cyclooxygenase activity. Clin. Exp. Pharmacol. Physiol. 2018 45:75-83 PubMed ID: 28815657 DOI: 10.1111/1440-1681.12846

10542 Matsumoto K, Shimo T, Kurio N, Okui T, Ibaragi S, Kunisada Y, Obata K, Masui M, Pai P, Horikiri Y, Yamanaka N, Takigawa M, Sasaki A. Low-intensity pulsed ultrasound stimulation promotes osteoblast differentiation through hedgehog signaling. J. Cell. Biochem. 2018 119:4352-4360 PubMed ID: 28981158 DOI: 10.1002/jcb.26418

10643 Mikami R, Mizutani K, Aoki A, Tamura Y, Aoki K, Izumi Y. Low-level ultrahigh-frequency and ultrashort-pulse blue laser irradiation enhances osteoblast extracellular calcification by upregulating proliferation and differentiation via transient receptor potential vanilloid 1. Lasers Surg Med 2018 50:340-352 PubMed ID: 29214666 DOI: 10.1002/lsm.22775

10657 Kawai S, Yamauchi M, Amano A. Zinc-finger transcription factor Odd-skipped related 1 regulates cranial bone formation. J. Bone Miner. Metab. 2018 36(6):640-647 PubMed ID: 29234951 DOI: 10.1007/s00774-017-0885-9

10666 Takeno A, Kanazawa I, Notsu M, Tanaka KI, Sugimoto T. Inhibition of adenosine monophosphate-activated protein kinase suppresses bone morphogenetic protein-2-induced mineralization of osteoblasts via Smad-independent mechanisms. Endocr. J. 2018 65:291-298 PubMed ID: 29249772 DOI: 10.1507/endocrj.EJ17-0229

19320 Chawalitpong S, Chokchaisiri R, Suksamrarn A, Katayama S, Mitani T, Nakamura S, Athamneh AA, Ritprajak P, Leelahavanichkul A, Aeimlapa R, Charoenphandhu N, Palaga T. Cyperenoic acid suppresses osteoclast differentiation and delays bone loss in a senile osteoporosis mouse model by inhibiting non-canonical NF-κB pathway Sci Rep 2018 8(1):5625 PubMed ID: 29618833 DOI: 10.1038/s41598-018-23912-3

10701 Kunimatsu R, Gunji H, Tsuka Y, Yoshimi Y, Awada T, Sumi K, Nakajima K, Kimura A, Hiraki T, Abe T, Naoto H, Yanoshita M, Tanimoto K. Effects of high-frequency near-infrared diode laser irradiation on the proliferation and migration of mouse calvarial osteoblasts. Lasers Med Sci 2018 33(5):959-966 PubMed ID: 29302842 DOI: 10.1007/s10103-017-2426-0

10716 Kwon BJ, Seon GM, Lee MH, Koo MA, Kim MS, Kim D, Han JJ, Kim D, Kim J, Park JC. Locally delivered ethyl-2,5-dihydroxybenzoate using 3D printed bone implant for promotion of bone regeneration in a osteoporotic animal model. Eur Cell Mater 2018 35:1-12 PubMed ID: 29327779 DOI: 10.22203/eCM.v035a01

10764 Takeda T, Tsubaki M, Tomonari Y, Kawashima K, Itoh T, Imano M, Satou T, Nishida S. Bavachin induces the apoptosis of multiple myeloma cell lines by inhibiting the activation of nuclear factor kappa B and signal transducer and activator of transcription 3. Biomed. Pharmacother. 2018 100:486-494 PubMed ID: 29477912 DOI: 10.1016/j.biopha.2018.02.019

10789 Yang DU, Siddiqi MH, Ahn S, Kang S, Noh HY, Yang DC. In vitro evaluation of the potential therapeutic role of Dendropanax morbifera extract in ameliorating osteoporosis and resultant bone impairment using MC3T3-E1 cells. In Vitro Cell. Dev. Biol. Anim. 2018 54:346-354 PubMed ID: 29560558 DOI: 10.1007/s11626-018-0242-x

10802 Funaki Y, Hasegawa Y, Okazaki R, Yamasaki A, Sueda Y, Yamamoto A, Yanai M, Fukushima T, Harada T, Makino H, Shimizu E. Resolvin E1 Inhibits Osteoclastogenesis and Bone Resorption by Suppressing IL-17-induced RANKL Expression in Osteoblasts and RANKL-induced Osteoclast Differentiation. Yonago Acta Med 2018 61:8-18 PubMed ID: 29599617 DOI: 10.33160/yam.2018.03.002

10846 Fushimi S, Nohno T, Nagatsuka H, Katsuyama H. Involvement of miR-140-3p in Wnt3a and TGFβ3 signaling pathways during osteoblast differentiation in MC3T3-E1 cells. Genes Cells 2018 23(7):517-527 PubMed ID: 29740905 DOI: 10.1111/gtc.12591

11034 A systematic study for optimal cell seeding and culture conditions in a perfusion mode bone-tissue bioreactor Biochemical Engineering Journal 2018 132, 100-111 DOI: 10.1016/j.bej.2018.01.006

11041 Ciona intestinalis calcitonin-like peptide promotes osteoblast differentiation and mineralization through MAPK pathway in MC3T3-E1 cells Process Biochemistry 2018 67, 127-138 DOI: 10.1016/j.procbio.2018.01.025

11068 The Synergistic Effects of IL-6/IL-17A Promote Osteogenic Differentiation by Improving OPG/RANKL Ratio and Adhesion of MC3T3-E1 Cells on Hydroxyapatite Journal of Cranio-Maxillofacial Surgery 2018 46,1361-1367 PubMed ID: 29805067 DOI: 10.1016/j.jcms.2018.05.002

11077 Kato K, Morita K, Hirata I, Doi K, Kubo T, Kato K, Tsuga K. Enhancement of calcification by osteoblasts cultured on hydroxyapatite surfaces with adsorbed inorganic polyphosphate. In Vitro Cell. Dev. Biol. Anim. 2018 54(6):449-457 PubMed ID: 29766357 DOI: 10.1007/s11626-018-0257-3

11129 Gonzalez-Garcia C, Cantini M, Ballester-Beltran J, Altankov G, Salmeron-Sanchez M. The strength of the protein-material interaction determines cell fate. Acta Biomater 2018 77:74-84 PubMed ID: 30006313 DOI: 10.1016/j.actbio.2018.07.016

11146 Fujioka-Kobayashi M, Tsuru K, Nagai H, Fujisawa K, Kudoh T, Ohe G, Ishikawa K, Miyamoto Y. Fabrication and evaluation of carbonate apatite-coated calcium carbonate bone substitutes for bone tissue engineering. J Tissue Eng Regen Med 2018 12(10):2077-2087 PubMed ID: 30058260 DOI: 10.1002/term.2742

11221 Khalid H, Suhaib F, Zahid S, Ahmed S, Jamal A, Kaleem M, Khan AS. Microwave-assisted synthesis and in vitro osteogenic analysis of novel bioactive glass fibers for biomedical and dental applications. Biomed Mater 2018 PubMed ID: 30251708 DOI: 10.1088/1748-605X/aae3f0

11138 Fukuda M, Yoshizawa T, Karim MF, Sobuz SU, Korogi W, Kobayasi D, Okanishi H, Tasaki M, Ono K, Sawa T, Sato Y, Chirifu M, Masuda T, Nakamura T, Tanoue H, Nakashima K, Kobashigawa Y, Morioka H, Bober E, Ohtsuki S, Yamagata Y, Ando Y, Oike Y, Araki N, Takeda S, Mizuta H, Yamagata K. SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix. Nat Commun 2018 9(1):2833 PubMed ID: 30026585 DOI: 10.1038/s41467-018-05187-4

11254 Bai Y, Kanno T, Tatsumi H, Miyamoto K, Sha J, Hideshima K, Matsuzaki Y. Feasibility of a Three-Dimensional Porous Uncalcined and Unsintered Hydroxyapatite/poly-d/l-lactide Composite as a Regenerative Biomaterial in Maxillofacial Surgery. Materials (Basel) 2018 PubMed ID: 30347816 DOI: 10.3390/ma11102047

11265 Sato M, Asano T, Hosomichi J, Ono T, Nakata T. Optogenetic manipulation of intracellular calcium by BACCS promotes differentiation of MC3T3-E1 cells. Biochem. Biophys. Res. Commun. 2018 PubMed ID: 30376992 DOI: 10.1016/j.bbrc.2018.10.107

11261 Marcotti S, Maki K, Reilly GC, Lacroix D, Adachi T. Hyaluronic acid selective anchoring to the cytoskeleton: An atomic force microscopy study. PLoS ONE 2018 PubMed ID: 30359403 DOI: 10.1371/journal.pone.0206056

11267 Oyane A, Nakamura M, Sakamaki I, Shimizu Y, Miyata S, Miyaji H. Laser-assisted wet coating of calcium phosphate for surface-functionalization of PEEK. PLoS ONE 2018 PubMed ID: 30379904 DOI: 10.1371/journal.pone.0206524

11352 Choi H, Magyar CE, Nervina JM, Tetradis S. Different duration of parathyroid hormone exposure distinctively regulates primary response genes Nurr1 and RANKL in osteoblasts. PLoS ONE 2018 PubMed ID: 30576321 DOI: 10.1371/journal.pone.0208514

4411 Yuka Yashima, View ORCID ProfileMasato Kaku, Taeko Yamamoto, Jin Izumino, Haruka Kagawa, Kotaro Tanimoto Effect of continuous compressive force on the expression of RANKL, OPG, and VEGF in MC3T3-E1 and MLO-Y4 cells bioRxiv 2018 19 DOI: 10.1101/474254

4412 Katsuya SATO, Manabu KATAYAMA, Shoichiro FUJISAWA, Tasuku NAKAHARA, Kazuyuki MINAMI Evaluation of initiating characteristics of osteoblastic calcium signaling responses to stretch by video rate time-course observation Journal of Biomechanical Science and Engineering 2018 13 DOI: 10.1299/jbse.17-00519

4413 Abbas Teimouri, Email author, Shahin Roohafza, Mohammad Azadi, Alireza Najafi Chermahini Fabrication and characterization of chitosan/gelatin/nanodiopside composite scaffolds for tissue engineering application Polymer Bulletin 2018 75:1487–1504 DOI: 10.1007/s00289-017-2096-x

4414 Visible light-induced antibacterial effects of the luminescent complex of hydroxyapatite and 8-hydroxyquinoline with gray titania coating Applied Surface Science 2018 448, 529-538 DOI: 10.1016/j.apsusc.2018.04.106

4416 Collagen-derived X-Hyp-Gly-type tripeptides promote differentiation of MC3T3-E1 pre-osteoblasts Journal of Functional Foods 2018 46, 456-462 DOI: 10.1016/j.jff.2018.05.017

4417 Improving Magnetoelectric Contactless Sensing and Actuation through Anisotropic Nanostructures J. Phys. Chem. 2018 122:19189-9196 DOI: 10.1021/acs.jpcc.8b04910

4418 Nobuo Izumo et al Effects of lactoferrin on dexamethasone-induced osteoporosis in mice Take a look at the Recent articles 2018 3(3):5-5 DOI: 10.15761/GDT.1000149

4419 Kubota T, Hasuike A, Tsukune N, Ozawa Y, Yamamoto T, Min S, Naito M5, Sato S. Influence of estrogen deficiency on guided bone augmentation: investigation of rat calvarial model and osteoblast‐like MC3T3‐E1 cells Eur J Oral Sci 2018 126(3):206-213 PubMed ID: 29676477 DOI: 10.1111/eos.12415

4281 Takahashi A, Mulati M, Saito M, Numata H, Kobayashi Y, Ochi H, Sato S, Kaldis P, Okawa A, Inose H. Loss of cyclin-dependent kinase 1 impairs bone formation, but does not affect the bone-anabolic effects of parathyroid hormone. J. Biol. Chem. 2018 PubMed ID: 30366983 DOI: 10.1074/jbc.RA118.004834

4282 Ando K, Imagama S, Kobayashi K, Ito K, Tsushima M, Morozumi M, Tanaka S, Machino M, Ota K, Nishida K, Nishida Y, Ishiguro N. Effects of a self-assembling peptide as a scaffold on bone formation in a defect. PLoS ONE 2018 PubMed ID: 29304115 DOI: 10.1371/journal.pone.0190833

4283 Kawamoto K, Miyaji H, Nishida E, Miyata S, Kato A, Tateyama A, Furihata T, Shitomi K, Iwanaga T, Sugaya T. Characterization and evaluation of graphene oxide scaffold for periodontal wound healing of class II furcation defects in dog. Int J Nanomedicine 2018 PubMed ID: 29713167 DOI: 10.2147/IJN.S163206

4489 iho Inoue, Mio Naritani, Resmi Raju, Mayu Miyagi, Masamitsu Oshima, Masahisa Inoue and Yoshizo Matsuka Effect of Short-term Tumour Necrosis Factor-alpha (TNF-α)-stimulation on the Growth and Differentiation of MC3T3-E1 Osteoblast-like Cells Journal of Hard Tissue Biology 2018 27:213-218 DOI: 10.2485/jhtb.27.213

4490 Kenichi Matsuzaka, Tadashi Horikawa, Eitoyo Kokubu and Takashi Inoue Oral epithelial cells inhibit the proliferation, mRNA expressions of collagen type I, RUNX2 and BGP, and ALP activity of osteoblast-like cells in co-culture. Biomedical Research 2018 29 (15):3085-3089 DOI: 10.4066/biomedicalresearch.29-18-900

4491 Graef JL, Rendina-Ruedy E, Crockett EK, Ouyang P, King JB, Cichewicz RH, Lucas EA, Smith BJ. Select polyphenolic fractions from dried plum enhance osteoblast activity through BMP-2 signaling. J. Nutr. Biochem. 2018 55:59-67 PubMed ID: 29413490 DOI: 10.1016/j.jnutbio.2017.09.014

4493 Yoshihara C, Ueno T, Chen P, Tsutsumi Y, Hanawa T, Wakabayashi N. Inverse response of osteoblasts and fibroblasts to growth on carbon-deposited titanium surfaces. J. Biomed. Mater. Res. Part B Appl. Biomater. 2018 106(5):1869-1877 PubMed ID: 28926194 DOI: 10.1002/jbm.b.33996

9463 Takashi Takizawa, Noboru Nakayama, Hisao Haniu, Kaoru Aoki, Masanori Okamoto, Hiroki Nomura, Manabu Tanaka, Atsushi Sobajima, Kazushige Yoshida, Takayuki Kamanaka, Kumiko Ajima, Ayumu Oishi, Chika Kuroda, Haruka Ishida, Satomi Okano, Shinsuke Kobayashi, Hiroyuki Kato, and Naoto Saito Titanium Fiber Plates for Bone Tissue Repair Adv Mater 2018 30:1703608 PubMed ID: 29215204 DOI: 10.1002/adma.201703608

9464 Mariko Urata, Shoichiro Kokabu, Takuma Matsubara, Goro Sugiyama, Chihiro Nakatomi, Hiroshi Takeuchi, Shizu Hirata-Tsuchiya, Kazuhiro Aoki, Yukihiko Tamura, Yasuko Moriyama, Yasunori Ayukawa, Miho Matsuda, Min Zhang, Kiyoshi Koyano, Chiaki Kitamura, Eijiro Jimi A Peptide That Blocks the Interaction of NF-κB p65 Subunit With Smad4 Enhances BMP2-induced Osteogenesis J Cell Physiol 2018 233(9):7356-7366 PubMed ID: 29663368 DOI: 10.1002/jcp.26571

9465 Tomohiko Tokunaga, Takashi Ando, Miki Suzuki-Karasaki, Tomohisa Ito, Asuka Onoe-Takahashi, Toyoko Ochiai, Masayoshi Soma , Yoshihiro Suzuki-Karasaki Plasma-stimulated Medium Kills TRAIL-resistant Human Malignant Cells by Promoting Caspase-Independent Cell Death via Membrane Potential and Calcium Dynamics Modulation Int J Oncol 2018 52(3):697-708 PubMed ID: 29393427 DOI: 10.3892/ijo.2018.4251

14601 Ilyas K, Qureshi SW, Afzal S, Gul R, Yar M, Kaleem M, Khan AS. Microwave-assisted synthesis and evaluation of type 1 collagen-apatite composites for dental tissue regeneration J Biomater Appl 2018 33(1):103-115 PubMed ID: 29720018 DOI: 10.1177/0885328218773220

14908 Jeong Y, Jo YK, Kim BJ, Yang B, Joo KI, Cha HJ. Sprayable Adhesive Nanotherapeutics: Mussel-Protein-Based Nanoparticles for Highly Efficient Locoregional Cancer Therapy ACS Nano 2018 12(9):8909-8919 PubMed ID: 30052423 DOI: 10.1021/acsnano.8b04533

9716 Kitagawa M, Ando T, Subarnbhesaj A, Uchida T, Miyauchi M, Takata T. N-terminal region of human ameloblastin synthetic peptide promotes bone formation. Odontology 2017 105:116-121 PubMed ID: 27262724 DOI: 10.1007/s10266-016-0243-8

9825 Teimouri A, Azadi M, Shams Ghahfarokhi Z, Razavizadeh R. Preparation and characterization of novel β-chitin/nanodiopside/nanohydroxyapatite composite scaffolds for tissue engineering applications. J Biomater Sci Polym Ed 2017 28:1-14 PubMed ID: 27604099 DOI: 10.1080/09205063.2016.1231437

9870 Takano-Yamamoto T, Fukunaga T, Takeshita N. Gene Expression Analysis of CCN Protein in Bone Under Mechanical Stress. Methods Mol. Biol. 2017 1489:283-308 PubMed ID: 27734385 DOI: 10.1007/978-1-4939-6430-7_26

9876 Kaynak Bayrak G, Demirtaş TT, Gümüşderelioğlu M. Microwave-induced biomimetic approach for hydroxyapatite coatings of chitosan scaffolds. Carbohydr Polym 2017 157:803-813 PubMed ID: 27987994 DOI: 10.1016/j.carbpol.2016.10.016

9934 Kanazawa I, Tomita T, Miyazaki S, Ozawa E, Yamamoto LA, Sugimoto T. Bazedoxifene Ameliorates Homocysteine-Induced Apoptosis and Accumulation of Advanced Glycation End Products by Reducing Oxidative Stress in MC3T3-E1 Cells. Calcif. Tissue Int. 2017 100:286-297 PubMed ID: 27832315 DOI: 10.1007/s00223-016-0211-x

9942 Pawaputanon Na Mahasarakham C, Izu Y, Nishimori K, Izumi Y, Noda M, Ezura Y. Lgr4 Expression in Osteoblastic Cells Is Suppressed by Hydrogen Peroxide Treatment. J. Cell. Physiol. 2017 232:1761-1766 PubMed ID: 27861872 DOI: 10.1002/jcp.25684

9951 Ode T, Podyma-Inoue KA, Terasawa K, Inokuchi JI, Kobayashi T, Watabe T, Izumi Y, Hara-Yokoyama M. PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum. Exp. Cell Res. 2017 350:103-114 PubMed ID: 27865938 DOI: 10.1016/j.yexcr.2016.11.011

9960 Noguchi T, Ebina K, Hirao M, Morimoto T, Koizumi K, Kitaguchi K, Matsuoka H, Iwahashi T, Yoshikawa H. Oxygen ultra-fine bubbles water administration prevents bone loss of glucocorticoid-induced osteoporosis in mice by suppressing osteoclast differentiation. Osteoporos Int 2017 28:1063-1075 PubMed ID: 27896363 DOI: 10.1007/s00198-016-3830-1

9976 Katsumura S, Izu Y, Yamada T, Griendling K, Harada K, Noda M, Ezura Y. FGF Suppresses Poldip2 Expression in Osteoblasts. J. Cell. Biochem. 2017 118:1670-1677 PubMed ID: 27918072 DOI: 10.1002/jcb.25813

9994 Arahira T, Maruta M, Matsuya S. Characterization and in vitro evaluation of biphasic α-tricalcium phosphate/β-tricalcium phosphate cement. Mater Sci Eng C Mater Biol Appl 2017 74:478-484 PubMed ID: 28254321 DOI: 10.1016/j.msec.2016.12.049

10042 Tunçay EÖ, Demirtaş TT, Gümüşderelioğlu M. Microwave-induced production of boron-doped HAp (B-HAp) and B-HAp coated composite scaffolds. J Trace Elem Med Biol 2017 40:72-81 PubMed ID: 28159225 DOI: 10.1016/j.jtemb.2016.12.005

10058 Nagao M, Tanabe N, Manaka S, Naito M, Sekino J, Takayama T, Kawato T, Torigoe G, Kato S, Tsukune N, Maeno M, Suzuki N, Sato S. LIPUS suppressed LPS-induced IL-1α through the inhibition of NF-κB nuclear translocation via AT1-PLCβ pathway in MC3T3-E1 cells. J. Cell. Physiol. 2017 232:3337-3346 PubMed ID: 28063227 DOI: 10.1002/jcp.25777

10068 Sato Y, Ishihara N, Nagayama D, Saiki A, Tatsuno I. 7-ketocholesterol induces apoptosis of MC3T3-E1 cells associated with reactive oxygen species generation, endoplasmic reticulum stress and caspase-3/7 dependent pathway. Mol Genet Metab Rep 2017 10:56-60 PubMed ID: 28116245 DOI: 10.1016/j.ymgmr.2017.01.006

10074 Takano A, Fukuda T, Shinjo T, Iwashita M, Matsuzaki E, Yamamichi K, Takeshita M, Sanui T, Nishimura F. Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation. Metab. Clin. Exp. 2017 69:157-170 PubMed ID: 28285646 DOI: 10.1016/j.metabol.2017.01.006

10084 Kodama D, Hirai T, Kondo H, Hamamura K, Togari A. Bidirectional communication between sensory neurons and osteoblasts in an in vitro coculture system. FEBS Lett. 2017 591:527-539 PubMed ID: 28094440 DOI: 10.1002/1873-3468.12561

10139 Tsukune N, Naito M, Kubota T, Ozawa Y, Nagao M, Ohashi A, Sato S, Takahashi T. Lamin A overexpression promotes osteoblast differentiation and calcification in the MC3T3-E1 preosteoblastic cell line. Biochem. Biophys. Res. Commun. 2017 488:664-670 PubMed ID: 28237702 DOI: 10.1016/j.bbrc.2017.02.110

10140 Tanaka M, Sato Y, Haniu H, Nomura H, Kobayashi S, Takanashi S, Okamoto M, Takizawa T, Aoki K, Usui Y, Oishi A, Kato H, Saito N. A three-dimensional block structure consisting exclusively of carbon nanotubes serving as bone regeneration scaffold and as bone defect filler. PLoS ONE 2017 12:e0172601 PubMed ID: 28235026 DOI: 10.1371/journal.pone.0172601

10217 Kusuyama J, Bandow K, Ohnishi T, Hisadome M, Shima K, Semba I, Matsuguchi T. Osteopontin inhibits osteoblast responsiveness through the down-regulation of focal adhesion kinase mediated by the induction of low-molecular weight protein tyrosine phosphatase. Mol. Biol. Cell 2017 28:1326-1336 PubMed ID: 28331074 DOI: 10.1091/mbc.E16-10-0716

10349 Sekiguchi Y, Mano H, Nakatani S, Shimizu J, Kataoka A, Ogura K, Kimira Y, Ebata M, Wada M. Mangiferin positively regulates osteoblast differentiation and suppresses osteoclast differentiation. Mol Med Rep 2017 16:1328-1332 PubMed ID: 28627701 DOI: 10.3892/mmr.2017.6752

10352 Nathanael AJ, Oyane A, Nakamura M, Sakamaki I, Nishida E, Kanemoto Y, Miyaji H. In Vitro and in Vivo Analysis of Mineralized Collagen-Based Sponges Prepared by a Plasma- and Precursor-Assisted Biomimetic Process. ACS Appl Mater Interfaces 2017 9:22185-22194 PubMed ID: 28621514 DOI: 10.1021/acsami.7b04776

10376 Nagao M, Tanabe N, Manaka S, Takayama T, Kawato T, Torigoe G, Sekino J, Tsukune N, Ozaki M, Maeno M, Suzuki N, Sato S. Low-intensity pulsed ultrasound inhibits lipopolysaccharide-induced IL-6 and RANKL expression in osteoblasts. J Oral Sci 2017 59:303-309 PubMed ID: 28637991 DOI: 10.2334/josnusd.16-0624

10405 Yahara M, Tei K, Tamura M. Inhibition of neuropeptide Y Y1 receptor induces osteoblast differentiation in MC3T3‑E1 cells. Mol Med Rep 2017 16:2779-2784 PubMed ID: 28656295 DOI: 10.3892/mmr.2017.6866

10441 Rodriguez R, Yoshimura K, Shibata Y, Miyamoto Y, Tanaka R, Uyama R, Sasa K, Suzuki D, Miyazaki T, Kamijo R. Nanoindentation time-dependent deformation/recovery suggestive of methylglyoxal induced glycation in calcified nodules. Nanomedicine 2017 13:2545-2553 PubMed ID: 28754466 DOI: 10.1016/j.nano.2017.07.003

10502 Chen P, Miyake M, Tsukamoto M, Tsutsumi Y, Hanawa T. Response of preosteoblasts to titanium with periodic micro/nanometer scale grooves produced by femtosecond laser irradiation. J Biomed Mater Res A 2017 105:3456-3464 PubMed ID: 28879673 DOI: 10.1002/jbm.a.36202

10528 Saiki A, Motoyoshi M, Motozawa K, Okamura T, Ueki K, Shimizu N, Asano M. EMMPRIN Inhibits bFGF-Induced IL-6 Secretion in an Osteoblastic Cell Line, MC3T3-E1. Int J Med Sci 2017 14:1173-1180 PubMed ID: 29104472 DOI: 10.7150/ijms.20387

10565 Torigoe G, Nagao M, Tanabe N, Manaka S, Kariya T, Kawato T, Sekino J, Kato S, Maeno M, Suzuki N, Shimizu N. PYK2 mediates BzATP-induced extracellular matrix proteins synthesis. Biochem. Biophys. Res. Commun. 2017 494:663-667 PubMed ID: 29061307 DOI: 10.1016/j.bbrc.2017.10.107

10903 Surface chemistry and osteoblast-like cell response on a titanium surface modified by a focused Nd:YAG laser Surface and Coatings Technology 2017 309, 220-226 DOI: 10.1016/j.surfcoat.2016.10.024

10909 Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications Composites Part B: Engineering 2017 111, 37-44 DOI: 10.1016/j.compositesb.2016.12.014

10918 Effects of a Chemically Synthesized Leucine-Rich Amelogenin Peptide (csLRAP) on Chondrogenic and Osteogenic Cells Journal of Hard Tissue Biology 2017 26, 51- 60 DOI: 10.2485/jhtb.26.51

10920 A. Ghanem, Yunhe Lu, Tianyi Cai, Xiongzheng Mu Overexpression of RBP4 promotes proliferation, differentiation and mineralization of MC3T3-E1 Int J Clin Exp Pathol 2017 10:298-305

10928 Enhance the Bioactivity and Osseointegration of the Polyethylene-Terephthalate-Based Artificial Ligament via Poly(Dopamine) Coating with Mesoporous Bioactive Glass Advanced Engineering Materials banner 2017 19 DOI: 10.1002/adem.201600708

10935 Antibacterial effect of nickel-titanium alloy owing to nickel ion release Applied Surface Science 2017 405, 215-219 DOI: 10.1016/j.apsusc.2017.02.037

10970 Evaluation of the enhancement of osteogenesis by Zn-releasing diamond-like carbon film Diamond and Related Materials 2017 77, 131-136 DOI: 10.1016/j.diamond.2017.06.006

10982 Development of a Ta/TaN/TaNx(Ag)y/TaN nanocomposite coating system and bio-response study for biomedical applications Vacuum 2017 145, 55-67 DOI: 10.1016/j.vacuum.2017.08.020

10989 Effects of three-dimensional culture of mouse calvaria-derived osteoblastic cells in a collagen gel with a multichannel structure on the morphogenesis behaviors of engineered bone tissues ACS Biomater. Sci. Eng. 2017 3 , 3414–3424 PubMed ID: 33445380 DOI: 10.1021/acsbiomaterials.7b00190

10998 Antibacterial and cytotoxic effects of photoexcited Au clusters via blue high-power or white low-power lightemitting diode irradiation Biology, Engineering and Medicine 2017 2:4 DOI: 10.15761/BEM.1000126

11001 Anti-Osteoporotic Effects of Kukoamine B in Osteoblast and Osteoclast Cells and Ovariectomized Mice medicinal chemistry 2017 2017100196 DOI: 10.20944/preprints201710.0196.v1

11013 In Situ Observation and Measurement of Actin Stress Fiber Deformation in Stretched Osteoblast like Cell Advances in Bioscience and Biotechnology, 2017 8, 421-433 DOI: 10.4236/abb.2017.811031

11044 Attachment of Mouse Osteoblast-like Cells onto Fibronectin-or Albumin-immobilized Poly (Lactic Acid-ε-Caprolactone) Films Journal of Oral Tissue Engineering 2017 15, 3-10 DOI: 10.11223/jarde.15.3

4521 Drago Skrtic and Joseph M. Antonucci Bioactive ACP-Based Polymeric Biocomposite Biomaterials for Tissue Engineering 2017 4:90-142 DOI: 10.2174/97816810853641170401

6639 Ota T, Nishida Y, Ikuta K, Kato R, Kozawa E, Hamada S, Sakai T, Ishiguro N. Heat-stimuli-enhanced osteogenesis using clinically available biomaterials. PLoS One 2017 12(7):e0181404 PubMed ID: 28719650 DOI: 10.1371/journal.pone.0181404

9435 Takuya Yasukawa, Makoto Hayashi, Natsuko Tanabe, Hiromasa Tsuda, Yusuke Suzuki, Takayuki Kawato, Naoto Suzuki, Masao Maeno, Bunnai Ogiso Involvement of the Calcium-Sensing Receptor in Mineral Trioxide Aggregate-Induced Osteogenic Gene Expression in Murine MC3T3-E1 Cells Dent Mater J 2017 36(4):469-475 PubMed ID: 28228629 DOI: 10.4012/dmj.2016-313

9436 Midori Katsuyama, Masashi Demura, Hironobu Katsuyama, Hideji Tanii, Kiyofumi Saijoh Genistein and menaquinone-4 Treatment-Induced Alterations in the Expression of mRNAs and Their Products Are Beneficial to Osteoblastic MC3T3-E1 Cell Functions Mol Med Rep 2017 6(1):873-880 PubMed ID: 28560445 DOI: 10.3892/mmr.2017.6632

9438 Haruaki Kitagawa, Kahoru Takeda, Ririko Tsuboi, Mikako Hayashi, Jun-Ichi Sasaki, Satoshi Imazato Influence of Polymerization Properties of 4-META/MMA-based Resin on the Activity of Fibroblast Growth factor-2 Dent Mater J 2017 36(6):724-730 PubMed ID: 28626207 DOI: 10.4012/dmj.2016-372

9439 Saori Miyata, Hirofumi Miyaji, Hideya Kawasaki, Masaki Yamamoto, Erika Nishida, Hiroko Takita, Tsukasa Akasaka, Natsumi Ushijima, Toshihiko Iwanaga, Tsutomu Sugaya Antimicrobial Photodynamic Activity and Cytocompatibility of Au 25(Capt) 18 Clusters Photoexcited by Blue LED Light Irradiation Int J Nanomedicine . 2017 Apr 4;12:2703-2716 2017 12:2703-2716 PubMed ID: 28435253 DOI: 10.2147/IJN.S131602

9440 Keisuke Yasuda, Yohei Okazaki, Yasuhiko Abe, Kazuhiro Tsuga Effective UV/Ozone Irradiation Method for Decontamination of Hydroxyapatite Surfaces Heliyon 2017 3(8):e00372 PubMed ID: 28795167 DOI: 10.1016/j.heliyon.2017.e00372

9441 Satoshi Migita and Kunitaka Araki Effect of nanometer scale surface roughness of titanium for osteoblast function AIMS Bioengineering 2017 4:162-170

9442 Mohammad Azadi, Zahra Shams Ghahfarokhi and Abbas Teimouri Modification of Silk Fibroin and Gelatin-Chondroitin Sulfate Matrix with the Addition of Nanohydroxyapatite by FreezeDrying Method for Tissue Engineering Application J Pharm Appl Chem 2017 3:253-258 DOI: 10.18576/jpac/030308

9443 Manami Ozaki, Tadahiro Takayama, Takanobu Yamamoto, Yasumasa Ozawa, Mayu Nagao, Natsuko Tanabe, Akira Nakajima, Naoto Suzuki, Masao Maeno, Seiichi Yamano, Shuichi Sato A Collagen Membrane Containing Osteogenic protein-1 Facilitates Bone Regeneration in a Rat Mandibular Bone Defect Arch Oral Biol 2017 84:19-28 PubMed ID: 28938197 DOI: 10.1016/j.archoralbio.2017.09.005

9444 Yoko Oshima, Fuminori Iwasa, Keita Tachi, Kazuyoshi Baba Effect of Nanofeatured Topography on Ceria-Stabilized Zirconia/Alumina Nanocomposite on Osteogenesis and Osseointegration Int J Oral Maxillofac Implants 2017 32(1):81-91 PubMed ID: 28095516 DOI: 10.11607/jomi.4366

9445 Manabu Tanaka, Hisao Haniu, Takayuki Kamanaka, Takashi Takizawa, Atsushi Sobajima, Kazushige Yoshida, Kaoru Aoki, Masanori Okamoto, Hiroyuki Kato, Naoto Saito Physico-Chemical, In Vitro, and In Vivo Evaluation of a 3D Unidirectional Porous Hydroxyapatite Scaffold for Bone Regeneration Materials (Basel) . 2017 Jan 3;10(1):33 2017 10(1):33 PubMed ID: 28772390 DOI: 10.3390/ma10010033

9446 Shusuke Murakami, Hirofumi Miyaji, Erika Nishida, Kohei Kawamoto, Saori Miyata, Hiroko Takita, Tsukasa Akasaka, Bunshi Fugetsu, Toshihiko Iwanaga, Hiromi Hongo, Norio Amizuka, Tsutomu Sugaya, Masamitsu Kawanami Dose Effects of Beta-Tricalcium Phosphate Nanoparticles on Biocompatibility and Bone Conductive Ability of Three-Dimensional Collagen Scaffolds Dent Mater J 2017 36(5):573-583 PubMed ID: 28450672 DOI: 10.4012/dmj.2016-295

9449 Tuğrul Tolga Demirtaş, Gülseren Irmak, Menemşe Gümüşderelioğlu A Bioprintable Form of Chitosan Hydrogel for Bone Tissue Engineering Biofabrication 2017 9(3):035003 PubMed ID: 28639943 DOI: 10.1088/1758-5090/aa7b1d

9453 Jussi Ryynänen, Carsten Kriebitzsch, Mark B Meyer, Iris Janssens, J Wesley Pike, Lieve Verlinden, Annemieke Verstuyf Class 3 Semaphorins Are Transcriptionally Regulated by 1,25(OH) 2 D 3 in Osteoblasts Steroid Biochem Mol Biol 2017 173:185-193 PubMed ID: 28189595 DOI: 10.1016/j.jsbmb.2017.02.005

9455 Sachiko Nitta, Ayaka Komatsu, Taisei Ishii, Masatoshi Ohnishi, Atsuko Inoue, Hiroyuki Iwamoto Fabrication and Characterization of Water-Dispersed Chitosan Nanofiber/Poly(ethylene Glycol) Diacrylate/Calcium Phosphate-Based Porous Composites Carbohydr Polym 2017 174:1034-1040 PubMed ID: 28821025 DOI: 10.1016/j.carbpol.2017.06.111

9456 H Iijima, A Ito, M Nagai, J Tajino, S Yamaguchi, W Kiyan, A Nakahata, J Zhang, T Wang, T Aoyama, K Nishitani, H Kuroki Physiological Exercise Loading Suppresses Post-Traumatic Osteoarthritis Progression via an Increase in Bone Morphogenetic Proteins Expression in an Experimental Rat Knee Model Osteoarthritis Cartilage 2017 25(6):964-975 PubMed ID: 27965139 DOI: 10.1016/j.joca.2016.12.008

9458 Kosaku Kurata, Junpei Matsushita, Atsushi Furuno, Junichi Fujino, Hiroshi Takamatsu Assessment of Thermal Damage in Total Knee Arthroplasty Using an Osteocyte Injury Model J Orthop Res 2017 35(12):2799-2807 PubMed ID: 28485534 DOI: 10.1002/jor.23600

14575 Chunrong Yang, Huazhong Wu, Jianhua Wang Fabrication of Multiple Layered Scaffolds with Controlled Porous Micro-Architecture Materials Research 2017 20:349-355 DOI: 10.1590/1980-5373-mr-2016-0703

14662 Yuki Nakamura, Toshihiko Shiraishi A Study of a Cell Mechanosensing System Under Mechanical Vibration Considering its Modes of Vibration and Calcium Ion Response Volume 3: Biomedical and Biotechnology Engineering 2017 DOI: 10.1115/imece2017-71363

14751 Tanaka M, Sato Y, Zhang M, Haniu H, Okamoto M, Aoki K, Takizawa T, Yoshida K, Sobajima A, Kamanaka T, Kato H, Saito N. In Vitro and In Vivo Evaluation of a Three-Dimensional Porous Multi-Walled Carbon Nanotube Scaffold for Bone Regeneration Nanomaterials (Basel) 2017 7(2):46 PubMed ID: 28336879 DOI: 10.3390/nano7020046

14771 Yang C, Wu H, Wang J. Effect of steroidal saponins-loaded nano-bioglass/phosphatidylserine/collagen bone substitute on bone healing Biomed Tech (Berl) 2017 62(5):487-491 PubMed ID: 27831915 DOI: 10.1515/bmt-2016-0151

7091 M Azadi, A Teimouri, G Mehranzadeh Preparation, characterization and biocompatible properties of β-chitin/silk fibroin/nanohydroxyapatite composite scaffolds prepared by freeze-drying method. RSC Adv 2016 6:7048-7060 DOI: 10.1039/C5RA22987A

7108 Demirta? TT, Goz E, Karakecili A, Gumu?derelio?lu M. Combined delivery of PDGF-BB and BMP-6 for enhanced osteoblastic differentiation. J Mater Sci Mater Med 2016 27:12 PubMed ID: 26676858 DOI: 10.1007/s10856-015-5626-9

7118 Shirakawa J, Harada H, Noda M, Ezura Y. PTH-Induced Osteoblast Proliferation Requires Upregulation of the Ubiquitin-Specific Peptidase 2 (Usp2) Expression. Calcif. Tissue Int. 2016 98:306-15 PubMed ID: 26643174 DOI: 10.1007/s00223-015-0083-5

7136 Valanezhad A, Odatsu T, Udoh K, Shiraishi T, Sawase T, Watanabe I. Modification of resin modified glass ionomer cement by addition of bioactive glass nanoparticles. J Mater Sci Mater Med 2016 27:3 PubMed ID: 26610926 DOI: 10.1007/s10856-015-5614-0

7164 Yoneshima E, Okamoto K, Sakai E, Nishishita K, Yoshida N, Tsukuba T. The Transcription Factor EB (TFEB) Regulates Osteoblast Differentiation Through ATF4/CHOP-Dependent Pathway. J. Cell. Physiol. 2016 231:1321-33 PubMed ID: 26519689 DOI: 10.1002/jcp.25235

7178 Chen P, Nagai A, Tsutsumi Y, Ashida M, Doi H, Hanawa T. Differences in the calcification of preosteoblast cultured on sputter-deposited titanium, zirconium, and gold. J Biomed Mater Res A 2016 104:639-651 PubMed ID: 26488234 DOI: 10.1002/jbm.a.35598

7211 Nakamoto T, Izu Y, Kawasaki M, Notomi T, Hayata T, Noda M, Ezura Y. Mice Deficient in CIZ/NMP4 Develop an Attenuated Form of K/BxN-Serum Induced Arthritis. J. Cell. Biochem. 2016 117:970-7 PubMed ID: 26378628 DOI: 10.1002/jcb.25382

7282 Taniguchi Y, Kakura K, Yamamoto K, Kido H, Yamazaki J. Accelerated Osteogenic Differentiation and Bone Formation on Zirconia with Surface Grooves Created with Fiber Laser Irradiation. Clin Implant Dent Relat Res 2016 18:883-894 PubMed ID: 26179832 DOI: 10.1111/cid.12366

9510 Ribeiro C, Correia V, Martins P, Gama FM, Lanceros-Mendez S. Proving the suitability of magnetoelectric stimuli for tissue engineering applications. Colloids Surf B Biointerfaces 2016 140:430-436 PubMed ID: 26797659 DOI: 10.1016/j.colsurfb.2015.12.055

9521 Tanaka K, Hirai T, Kodama D, Kondo H, Hamamura K, Togari A. α1B -Adrenoceptor signalling regulates bone formation through the up-regulation of CCAAT/enhancer-binding protein δ expression in osteoblasts. Br. J. Pharmacol. 2016 173:1058-69 PubMed ID: 26750808 DOI: 10.1111/bph.13418

9528 Ogawa K, Miyaji H, Kato A, Kosen Y, Momose T, Yoshida T, Nishida E, Miyata S, Murakami S, Takita H, Fugetsu B, Sugaya T, Kawanami M. Periodontal tissue engineering by nano beta-tricalcium phosphate scaffold and fibroblast growth factor-2 in one-wall infrabony defects of dogs. J. Periodont. Res. 2016 51:758-767 PubMed ID: 27870141 DOI: 10.1111/jre.12352

9565 Iwatsuki M, Matsuoka M. Fluoride-induced c-Fos expression in MC3T3-E1 osteoblastic cells. Toxicol. Mech. Methods 2016 26:132-8 PubMed ID: 26862884 DOI: 10.3109/15376516.2015.1129570

9570 Yoo HY, Song YH, Foo M, Seo E, Hwang DS, Seo JH. Recombinant mussel proximal thread matrix protein promotes osteoblast cell adhesion and proliferation. BMC Biotechnol. 2016 16:16 PubMed ID: 26879700 DOI: 10.1186/s12896-016-0247-z

9596 Pengjam Y, Madhyastha H, Madhyastha R, Yamaguchi Y, Nakajima Y, Maruyama M. Anthraquinone Glycoside Aloin Induces Osteogenic Initiation of MC3T3-E1 Cells: Involvement of MAPK Mediated Wnt and Bmp Signaling. Biomol Ther (Seoul) 2016 24:123-31 PubMed ID: 26869456 DOI: 10.4062/biomolther.2015.106

9597 Kumagai M, Mishima T, Watanabe A, Harada T, Yoshida I, Fujita K, Watai M, Tawata S, Nishikawa K, Morimoto Y. 5,6-Dehydrokawain from Alpinia zerumbet promotes osteoblastic MC3T3-E1 cell differentiation. Biosci. Biotechnol. Biochem. 2016 80:1425-32 PubMed ID: 26940726 DOI: 10.1080/09168451.2016.1153959

9626 Saito A, Yoshimura K, Miyamoto Y, Kaneko K, Chikazu D, Yamamoto M, Kamijo R. Enhanced and suppressed mineralization by acetoacetate and β-hydroxybutyrate in osteoblast cultures. Biochem. Biophys. Res. Commun. 2016 473:537-44 PubMed ID: 27018251 DOI: 10.1016/j.bbrc.2016.03.109

9655 Hase E, Matsubara O, Minamikawa T, Sato K, Yasui T. In situ time-series monitoring of collagen fibers produced by standing-cultured osteoblasts using a second-harmonic-generation microscope. Appl Opt 2016 55:3261-7 PubMed ID: 27140096 DOI: 10.1364/AO.55.003261

9683 Tamura K, Naraba H, Hara T, Nakamura K, Yoshie M, Kogo H, Tachikawa E. A positive feedback loop between progesterone and microsomal prostaglandin E synthase-1-mediated PGE2 promotes production of both in mouse granulosa cells. Prostaglandins Other Lipid Mediat. 2016 123:56-62 PubMed ID: 27174800 DOI: 10.1016/j.prostaglandins.2016.05.002

9689 Correia DM, Sencadas V, Ribeiro C, Martins PM, Martins P, Gama FM, Botelho G, Lanceros-Méndez S. Processing and size range separation of pristine and magnetic poly(l-lactic acid) based microspheres for biomedical applications. J Colloid Interface Sci 2016 476:79-86 PubMed ID: 27209393 DOI: 10.1016/j.jcis.2016.05.012

9707 Zhang Q, Matsui H, Horiuchi H, Liang X, Sasaki K. A-Raf and C-Raf differentially regulate mechanobiological response of osteoblasts to guide mechanical stress-induced differentiation. Biochem. Biophys. Res. Commun. 2016 476:438-444 PubMed ID: 27240957 DOI: 10.1016/j.bbrc.2016.05.141

9745 Kang S, Siddiqi MH, Yoon SJ, Ahn S, Noh HY, Kumar NS, Kim YJ, Yang DC. Therapeutic potential of compound K as an IKK inhibitor with implications for osteoarthritis prevention: an in silico and in vitro study. In Vitro Cell. Dev. Biol. Anim. 2016 52:895-905 PubMed ID: 27368432 DOI: 10.1007/s11626-016-0062-9

9772 Sato M, Chen P, Tsutsumi Y, Shiota M, Hanawa T, Kasugai S. Effect of strontium ions on calcification of preosteoblasts cultured on porous calcium- and phosphate-containing titanium oxide layers formed by micro-arc oxidation. Dent Mater J 2016 35:627-34 PubMed ID: 27477229 DOI: 10.4012/dmj.2016-032

9776 Rendina-Ruedy E, Graef JL, Lightfoot SA, Ritchey JW, Clarke SL, Lucas EA, Smith BJ. Impaired glucose tolerance attenuates bone accrual by promoting the maturation of osteoblasts: Role of Beclin1-mediated autophagy. Bone Rep 2016 5:199-207 PubMed ID: 28580387 DOI: 10.1016/j.bonr.2016.08.001

9782 Chawalitpong S, Sornkaew N, Suksamrarn A, Palaga T. Diarylheptanoid from Curcuma comosa Roxb. suppresses RANKL-induced osteoclast differentiation by decreasing NFATc1 and c-Fos expression via MAPK pathway. Eur. J. Pharmacol. 2016 788:351-359 PubMed ID: 27523282 DOI: 10.1016/j.ejphar.2016.08.012

9832 Yang D, Okamura H, Morimoto H, Teramachi J, Haneji T. Protein phosphatase 2A Cα regulates proliferation, migration, and metastasis of osteosarcoma cells. Lab. Invest. 2016 96:1050-62 PubMed ID: 27617401 DOI: 10.1038/labinvest.2016.82

9850 Park E, Kim MC, Choi CW, Kim J, Jin HS, Lee R, Lee JW, Park JH, Huh D, Jeong SY. Effects of Dihydrophaseic Acid 3'-O-β-d-Glucopyranoside Isolated from Lycii radicis Cortex on Osteoblast Differentiation. Molecules 2016 21(9). pii: E1260 PubMed ID: 27657033 DOI: 10.3390/molecules21091260

10849 Junfeng WANG, Shukei SUGITA, Kazuaki NAGAYAMA, Takeo MATSUMOTO Dynamics of actin filaments of MC3T3-E1 cells during adhesion process to substrate Journal of Biomechanical Science and Engineering 2016 11:15-00637 DOI: 10.1299/jbse.15-00637

10858 Oki Matsubara; Eiji Hase; Takeo Minamikawa; Takeshi Yasui; Katsuya Sato In situ quantitative evaluation of osteoblastic collagen synthesis under cyclic strain by using second-harmonic-generation microscope SPIE BiOS 2016 9721 DOI: 10.1117/12.2214008

10860 Fabrication and in vitro characterization of electrospun poly (γ-glutamic acid)-silica hybrid scaffolds for bone regeneration Polymer 2016 91,106-117 DOI: 10.1016/j.polymer.2016.03.056

10865 Functional peptide KP24 enhances submandibular gland tissue growth in vitro Regenerative Therapy 2016 3, 108-113 PubMed ID: 31245481 DOI: 10.1016/j.reth.2016.02.006

10872 β-Chitin/gelatin/nanohydroxyapatite composite scaffold prepared through freeze-drying method for tissue engineering applications Polymer Bulletin 2016 73, 3513–3529 DOI: 10.1007/s00289-016-1691-6

10876 Advanced DLC coating technique on silicone-based tubular medical devices Surface and Coatings Technology 2016 307, 1084-1087 DOI: 10.1016/j.surfcoat.2016.06.067

10897 Modification of Composite Resin Surface with Carbon Nanotubes Enhances Cell Proliferation Nano Biomedicine 2016 8 DOI: 10.11344/nano.8.27

10898 Observations of intracellular tension dynamics of MC3T3-E1 cells during substrate adhesion using a FRET-based actinin tension sensor Journal of Biomechanical Science and Engineering 2016 11:16-00504 DOI: 10.1299/jbse.16-00504

10900 Cytocompatibility of Ti–6Al–7Nb through High-Pressure Torsion Processing MATERIALS TRANSACTIONS 2016 57, 2020-2025 DOI: 10.2320/matertrans.MI201515

10901 Cell Activity on Type 316L Stainless Steel with Self-Organized Nanopores Formed by Anodic Polarization Journal of the Japan Institute of Metals and Materials 2016 57:2065-2071 DOI: 10.2320/matertrans.MI201516

9377 Nur Farahiyah Mohammad,Radzali Othman , Nurul Asma Abdullah, Fei Yee YEOH In vitro Evaluation of Mesoporous Carbonated Hydroxyapatite in MC3T3-E1 Osteoblast Cells Procedia Chemistry 2016 19 :259 – 266 DOI: 10.1016/j.proche.2016.03.103

9402 S M Marques, P Rico I Carvalho, J L Gómez Ribelles, L Fialho, S Lanceros-Méndez, M Henriques, S Carvalho MC3T3-E1 Cell Response to Ti1-xAgx and Ag-TiNx Electrodes Deposited on Piezoelectric Poly(vinylidene Fluoride) Substrates for Sensor Applications ACS Appl Mater Interfaces 2016 8(6):4199-207 PubMed ID: 26840928 DOI: 10.1021/acsami.5b11922

9409 Nobutaka Sato 1, Jiro Ichikawa 1, Masanori Wako, Tetsuro Ohba, Masanori Saito, Hironao Sato, Kensuke Koyama, Tetsuo Hagino, Jonathan G Schoenecker, Takashi Ando, Hirotaka Haro Thrombin Induced by the Extrinsic Pathway and PAR-1 Regulated Inflammation at the Site of Fracture Repair Bone 2016 83:23-34 PubMed ID: 26475502 DOI: 10.1016/j.bone.2015.10.005

9410 Sunarso, Riki Toita, Kanji Tsuru, Kunio Ishikawa Immobilization of Calcium and Phosphate Ions Improves the Osteoconductivity of Titanium Implants Mater Sci Eng C Mater Biol Appl 2016 68:291-298 PubMed ID: 27524023 DOI: 10.1016/j.msec.2016.05.090

9411 Chen Chen, Hong Li, Changan Guo, Shiyi Chen Preparation and in vitro Evaluation of a Biomimetic Nanoscale Calcium Phosphate Coating on a Polyethylene Terephthalate Artificial Ligament Exp Ther Med 2016 12(1):302-306 PubMed ID: 27347053 DOI: 10.3892/etm.2016.3269

9412 Masahiko Terauchi, Takasuke Inada, Asato Tonegawa, Atsushi Tamura, Satoshi Yamaguchi, Kiyoshi Harada, Nobuhiko Yui Supramolecular Inclusion Complexation of Simvastatin With Methylated β-Cyclodextrins for Promoting Osteogenic Differentiation Int J Biol Macromol 2016 93(Pt B):1492-1498 PubMed ID: 26845478 DOI: 10.1016/j.ijbiomac.2016.01.114

9413 Erika Nishida, Hirofumi Miyaji, Akihito Kato, Hiroko Takita, Toshihiko Iwanaga, Takehito Momos, Kosuke Ogawa, Shusuke Murakami, Tsutomu Sugaya, Masamitsu Kawanami Graphene Oxide Scaffold Accelerates Cellular Proliferative Response and Alveolar Bone Healing of Tooth Extraction Socket Int J Nanomedicine 2016 11:2265-77 PubMed ID: 27307729 DOI: 10.2147/IJN.S104778

9415 Wanting Lin, Yoichi Ezura, Yayoi Izu, Smriti A C Aryal, Makiri Kawasaki, Pawaputanon Na Mahasarakham Chantida, Keiji Moriyama, Masaki Noda Profilin Expression Is Regulated by Bone Morphogenetic Protein (BMP) in Osteoblastic Cells J Cell Biochem 2016 117(3):621-8 PubMed ID: 26271366 DOI: 10.1002/jcb.25310

9417 Aysu Arslan, Soner Çakmak, Alper Cengiz, Menemşe Gümüşderelioğlu Poly(butylene Adipate-Co-Terephthalate) Scaffolds: Processing, Structural Characteristics and Cellular Responses J Biomater Sci Polym Ed 2016 27(18):1841-1859 PubMed ID: 27724793 DOI: 10.1080/09205063.2016.1239945

9420 Abbas Teimouri &Mohammad Azadi Preparation and characterization of novel chitosan/nanodiopside/nanohydroxyapatite composite scaffolds for tissue engineering applications International Journal of Polymeric Materials and Polymeric Biomaterials 2016 65:18 DOI: 10.1080/00914037.2016.1180606

9421 Yoshikazu Mikami, Hiromasa Tsuda, Yuko Akiyama, Masaki Honda, Noriyoshi Shimizu, Naoto Suzuki, Kazuo Komiyama Alkaline Phosphatase Determines Polyphosphate-Induced Mineralization in a Cell-Type Independent Manner J Bone Miner Metab 2016 34(6):627-637 PubMed ID: 26475372 DOI: 10.1007/s00774-015-0719-6

9422 Kumi Futawaka, Tetsuya Tagami, Yuki Fukuda, Rie Koyama, Ayaka Nushida, Shoko Nezu, Hironori Yamamoto, Miyuki Imamoto, Masato Kasahara, Kenji Moriyama Transcriptional Activation of the Wild-Type and Mutant Vitamin D Receptors by Vitamin D3 Analogs J Mol Endocrinol 2016 57(1):23-32 PubMed ID: 27154546 DOI: 10.1530/JME-16-0048

9423 Taegon Kang, Xavier Banquy, Jinhwa Heo, Chanoong Lim, Nathaniel A Lynd, Pontus Lundberg, Dongyeop X Oh, Han-Koo Lee, Yong-Ki Hong 2, Dong Soo Hwang, John Herbert Waite, Jacob N Israelachvili, Craig J Hawker Mussel-Inspired Anchoring of Polymer Loops That Provide Superior Surface Lubrication and Antifouling Properties ACS Nano 2016 10(1):930-7 PubMed ID: 26695175 DOI: 10.1021/acsnano.5b06066

9424 Ling Jin, Yosuke Nonaka, Shin Miyakawa, Masatoshi Fujiwara, Yoshikazu Nakamura Dual Therapeutic Action of a Neutralizing Anti-FGF2 Aptamer in Bone Disease and Bone Cancer Pain Mol Ther 2016 24(11):1974-1986 PubMed ID: 27506449 DOI: 10.1038/mt.2016.158

9425 Alexander C Allori, Edward H Davidson, Derek D Reformat, Alexander M Sailon, James Freeman, Adam Vaughan, David Wootton, Elizabeth Clark, John L Ricci, Stephen M Warren Design and Validation of a Dynamic Cell-Culture System for Bone Biology Research and Exogenous Tissue-Engineering Applications J Tissue Eng Regen Med 2016 10(10):E327-E336 PubMed ID: 24027138 DOI: 10.1002/term.1810

9426 Yuri Nakashima , Toru Mima, Mitsuru Yashiro, Tomohiro Sonou, Masaki Ohya, Asuka Masumoto, Shintaro Yamanaka, Daisuke Koreeda, Koichi Tatsuta, Yoshiyuki Hanba, Mari Moribata, Shigeo Negi, Takashi Shigematsu Expression and Localization of Fibroblast Growth Factor (FGF)23 and Klotho in the Spleen: Its Physiological and Functional Implications Growth Factors 2016 34(5-6):196-202 PubMed ID: 28095739 DOI: 10.1080/08977194.2016.1273222

9429 Drago Skrtic, Joseph M Antonucci Polymeric Dental Composites Based on Remineralizing Amorphous Calcium Phosphate Fillers Curr Trends Polym Sci 2016 17:1-31 PubMed ID: 29599572

9451 Masanobu Kamitakahara, Takashi Shirato, Taishi Yokoi, Hideaki Matsubara, Yasuaki Shibata, Tohru Ikeda Effect of Silicate Incorporation in Alpha-Tricalcium Phosphate on Behaviors of Osteoblast-Like Cells Key Engineering Materials 2016 720:90-94 DOI: 10.4028/www.scientific.net/KEM.720.90

12931 Ozeki N, Mogi M, Hase N, Hiyama T, Yamaguchi H, Kawai R, Kondo A, Nakata K. Wnt16 Signaling Is Required for IL-1β-Induced Matrix Metalloproteinase-13-Regulated Proliferation of Human Stem Cell-Derived Osteoblastic Cells Int J Mol Sci 2016 17(2):221 PubMed ID: 26861315 DOI: 10.3390/ijms17020221

13950 Zhu C, Zheng XF, Yang YH, Li B, Wang YR, Jiang SD, Jiang LS. LGR4 acts as a key receptor for R-spondin 2 to promote osteogenesis through Wnt signaling pathway Cell Signal 2016 28(8):989-1000 PubMed ID: 27140682 DOI: 10.1016/j.cellsig.2016.04.010

14148 Toshihiko Shiraishi, Tomohiro Fukuno Cell Response to Cyclic Strain at Focal Adhesions Biomedical and Biotechnology Engineering 2016 3 DOI: 10.1115/imece2016-66843

16612 Nnamchi PS, Obayi CS, Todd I, Rainforth MW. Mechanical and electrochemical characterisation of new Ti-Mo-Nb-Zr alloys for biomedical applications J Mech Behav Biomed Mater 2016 60:68-77 PubMed ID: 26773649 DOI: 10.1016/j.jmbbm.2015.12.023

7163 Nishide Y, Tousen Y, Tadaishi M, Inada M, Miyaura C, Kruger MC, Ishimi Y. Combined Effects of Soy Isoflavones and β-Carotene on Osteoblast Differentiation. Int J Environ Res Public Health 2015 12:13750-61 PubMed ID: 26516892 DOI: 10.3390/ijerph121113750

7220 Yang YJ, Tsou HK, Chen YH, Chung CJ, He JL. Enhancement of bioactivity on medical polymer surface using high power impulse magnetron sputtered titanium dioxide film. Mater Sci Eng C Mater Biol Appl 2015 57:58-66 PubMed ID: 26354240 DOI: 10.1016/j.msec.2015.07.039

7229 Inoue K, Imai Y. Fatostatin, an SREBP inhibitor, prevented RANKL-induced bone loss by suppression of osteoclast differentiation. Biochim. Biophys. Acta 2015 1852:2432-41 PubMed ID: 26319416 DOI: 10.1016/j.bbadis.2015.08.018

7241 Noguchi T, Ebina K, Hirao M, Kawase R, Ohama T, Yamashita S, Morimoto T, Koizumi K, Kitaguchi K, Matsuoka H, Kaneshiro S, Yoshikawa H. Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-α-induced osteoclastogenesis and promoting osteoblastic differentiation in mice. Biochem. Biophys. Res. Commun. 2015 465:638-43 PubMed ID: 26297947 DOI: 10.1016/j.bbrc.2015.08.077

7290 Uchino K, Okamoto K, Sakai E, Yoneshima E, Iwatake M, Fukuma Y, Nishishita K, Tsukuba T. Dual Effects of Liquiritigenin on the Proliferation of Bone Cells: Promotion of Osteoblast Differentiation and Inhibition of Osteoclast Differentiation. Phytother Res 2015 29:1714-21 PubMed ID: 26172226 DOI: 10.1002/ptr.5416

7302 Wang CH, Guo ZS, Pang F, Zhang LY, Yan M, Yan JH, Li KW, Li XJ, Li Y, Bi L, Han YS. Effects of graphene modification on the bioactivation of polyethylene-terephthalate-based artificial ligaments. ACS Appl Mater Interfaces 2015 7:15263-76 PubMed ID: 26111253 DOI: 10.1021/acsami.5b02893

7307 Hatano M, Matsumoto Y, Fukushi J, Matsunobu T, Endo M, Okada S, Iura K, Kamura S, Fujiwara T, Iida K, Fujiwara Y, Nabeshima A, Yokoyama N, Fukushima S, Oda Y, Iwamoto Y. Cadherin-11 regulates the metastasis of Ewing sarcoma cells to bone. Clin. Exp. Metastasis 2015 32:579-91 PubMed ID: 26092671 DOI: 10.1007/s10585-015-9729-y

7309 Fukuda K, Sugihara E, Ohta S, Izuhara K, Funakoshi T, Amagai M, Saya H. Periostin Is a Key Niche Component for Wound Metastasis of Melanoma. PLoS ONE 2015 10:e0129704 PubMed ID: 26083413 DOI: 10.1371/journal.pone.0129704

7325 Tanaka K, Hirai T, Ishibashi Y, Izumo N, Togari A. Modulation of osteoblast differentiation and bone mass by 5-HT2A receptor signaling in mice. Eur. J. Pharmacol. 2015 762:150-7 PubMed ID: 26026645 DOI: 10.1016/j.ejphar.2015.05.048

7332 Gumu?derelio?lu M, Tuncay EO, Kaynak G, Demirta? TT, Ayd?n ST, Hakk? SS. Encapsulated boron as an osteoinductive agent for bone scaffolds. J Trace Elem Med Biol 2015 31:120-8 PubMed ID: 26004902 DOI: 10.1016/j.jtemb.2015.03.008

7338 Kaneshiro S, Otsuki D, Yoshida K, Yoshikawa H, Higuchi C. MEK5 suppresses osteoblastic differentiation. Biochem. Biophys. Res. Commun. 2015 463:241-7 PubMed ID: 25998381 DOI: 10.1016/j.bbrc.2015.05.035

7374 Yang D, Okamura H, Teramachi J, Haneji T. Histone demethylase Utx regulates differentiation and mineralization in osteoblasts. J. Cell. Biochem. 2015 116:2628-36 PubMed ID: 25920016 DOI: 10.1002/jcb.25210

7431 Lin H, Gao X, Chen G, Sun J, Chu J, Jing K, Li P, Zeng R, Wei B. Indole-3-carbinol as inhibitors of glucocorticoid-induced apoptosis in osteoblastic cells through blocking ROS-mediated Nrf2 pathway. Biochem. Biophys. Res. Commun. 2015 460:422-7 PubMed ID: 25795137 DOI: 10.1016/j.bbrc.2015.03.049

7441 Terasawa K, Rajapakshe AR, Podyma-Inoue KA, Mishima-Tsumagari C, Yanagishita M, Hara-Yokoyama M. Preferential recognition of isocitrate dehydrogenase by a rabbit monoclonal antibody (ab124797) against the C-terminal peptide of RANKL. J. Immunol. Methods 2015 420:1-10 PubMed ID: 25771969 DOI: 10.1016/j.jim.2015.03.006

7444 Siddiqi MZ, Siddiqi MH, Kim YJ, Jin Y, Huq MA, Yang DC. Effect of Fermented Red Ginseng Extract Enriched in Ginsenoside Rg3 on the Differentiation and Mineralization of Preosteoblastic MC3T3-E1 Cells. J Med Food 2015 18:542-8 PubMed ID: 25764149 DOI: 10.1089/jmf.2014.3251

7445 Koike T, Mikami T, Shida M, Habuchi O, Kitagawa H. Chondroitin sulfate-E mediates estrogen-induced osteoanabolism. Sci Rep 2015 5:8994 PubMed ID: 25759206 DOI: 10.1038/srep08994

7455 Yamamura K, Miura T, Kou I, Muramatsu T, Furusawa M, Yoshinari M. Influence of various superhydrophilic treatments of titanium on the initial attachment, proliferation, and differentiation of osteoblast-like cells. Dent Mater J 2015 34:120-7 PubMed ID: 25748468 DOI: 10.4012/dmj.2014-076

7480 Saito T, Teraoka K, Ota K. Arrayed three-dimensional structures designed to induce and maintain a cell pattern by a topographical effect on cell behavior. Mater Sci Eng C Mater Biol Appl 2015 49:256-61 PubMed ID: 25686947 DOI: 10.1016/j.msec.2015.01.021

7491 Okito A, Nakahama K, Akiyama M, Ono T, Morita I. Involvement of the G-protein-coupled receptor 4 in RANKL expression by osteoblasts in an acidic environment. Biochem. Biophys. Res. Commun. 2015 458:435-40 PubMed ID: 25668130 DOI: 10.1016/j.bbrc.2015.01.142

7519 Abbas Teimouri, Mohammad Azadi, Rahmatollah Emadi, Jalil Lari, Alireza Najafi Chermahini Preparation, characterization, degradation and biocompatibility of different silk fibroin based composite scaffolds prepared by freeze-drying method for tissue engineering application. Polym Degrad Stab 2015 121:18-29 DOI: 10.1016/j.polymdegradstab.2015.08.004

7531 Hsien-Te Chen, Hui-Ying Shu, Chi-Jen Chung, Ju-Liang He Assessment of Bone Morphogenic Protein and Hydroxyapatite-Titanium Dioxide Composites for Bone Implant Materials. Surface and Coatings Technology 2015 276:168-174 DOI: 10.1016/j.surfcoat.2015.06.056

7538 Katsuya SATO, Yuki OGAWA, Shin-ichi ITO, Shoichiro FUJISAWA, Kazuyuki MINAMI Strain magnitude dependent intracellular calcium signaling response to uniaxial stretch in osteoblastic cells. J Biomechanical Science and Engineering 2015 10:15-00242 DOI: 10.1299/jbse.15-00242

7541 L.T. Bang, S. Ramesha,. Purbolaksono, Y.C. Chinga, B.D. Long, Hari Chandran, S. Rameshc, R. Othmand Effects of silicate and carbonate substitution on the properties of hydroxyapatite prepared by aqueous co-precipitation method. Materials and Design 2015 87:788?796 DOI: 10.1016/j.matdes.2015.08.069

7543 M. Hirano, M. Yamane, N. Ohtsu Surface characteristics and cell-adhesion performance of titanium treated with direct-current gas plasma comprising nitrogen and oxygen. Appl Surf Sci. 2015 354:161-167 DOI: 10.1016/j.apsusc.2015.02.153

7546 Megumi Fuse, Tohru Hayakawa, Tomomi Hashizume-Takizawa, Reiri Takeuchi, Tomoko Kurita-Ochiai, Junko Fujita-Yoshigaki, Masahiko Fukumoto MC3T3-E1 Cell Assay on Collagen or Fibronectin Immobilized Poly (Lactic Acid-ε-Caprolactone) Film. J Hard Tissue Biology 2015 24:249-256 DOI: 10.2485/jhtb.24.249

7549 Momoko Takahashi, Masaru Yamaguchi, Yasuhiro Tanimoto, Eriko Yao-Umezawa, Kazutaka Kasai Biological Evaluation of a Prototype Material made of Polyglycolic Acid and Hydroxyapatite. J Hard Tissue Biology 2015 24:375-384 DOI: 10.2485/jhtb.24.375

7551 Naofumi Ohtsu, Taro Kozuka, Mitsuhiro Hirano, Hirofumi Arai Electrolyte effects on the surface chemistry and cellular response of anodized titanium. Appl Surf Sci. 2015 349:911-915 DOI: 10.1016/j.apsusc.2015.05.046

7561 Takaaki Arahira, Mitsugu Todo. Effects of osteoblast-like cell seeding on the mechanical properties of porous composite scaffolds. Advanced Composite Materials 2015 24:79-90 DOI: 10.1080/09243046.2014.942942

7577 Yun Kee Jo, Bong-Hyuk Choi, Cong Zhou, Jin-Soo Ahn, Sang Ho Jun, Hyung Joon Cha Bioengineered mussel glue incorporated with a cell recognition motif as an osteostimulating bone adhesive for titanium implants. J Mater Chem B. 2015 3:8102-8114 PubMed ID: 32262867 DOI: 10.1039/c5tb01230a

7582 Masuda E, Shirai K, Maekubo K, Hirai Y. A newly established culture method highlights regulatory roles of retinoic acid on morphogenesis and calcification of mammalian limb cartilage. BioTechniques 2015 58:318-24 PubMed ID: 26054768 DOI: 10.2144/000114300

6618 Kim H, Tabata A, Tomoyasu T, Ueno T, Uchiyama S, Yuasa K, Tsuji A, Nagamune H. Estrogen stimuli promote osteoblastic differentiation via the subtilisin-like proprotein convertase PACE4 in MC3T3-E1 cells. J Bone Miner Metab 2015 33(1):30-9 PubMed ID: 24557631 DOI: 10.1007/s00774-014-0567-9

9146 Tadashi Goto, Keitaro Hagiwara, Nobuaki Shirai, Kaoru Yoshida, Hiromi Hagiwara Apigenin Inhibits Osteoblastogenesis and Osteoclastogenesis and Prevents Bone Loss in Ovariectomized Mice Cytotechnology 2015 67 (2), 357-65 PubMed ID: 24500394 DOI: 10.1007/s10616-014-9694-3

9188 Andy T H Wu 1, Teruo Aoki, Megumu Sakoda, Seiichi Ohta, Shigetoshi Ichimura, Taichi Ito, Takashi Ushida, Katsuko S Furukawa Enhancing Osteogenic Differentiation of MC3T3-E1 Cells by Immobilizing Inorganic Polyphosphate Onto Hyaluronic Acid Hydrogel Biomacromolecules 2015 16(1):166-73 PubMed ID: 25423088 DOI: 10.1021/bm501356c

9197 Soichiro Manaka, Natsuko Tanabe, Taro Kariya, Masako Naito, Tadahiro Takayama, Mayu Nagao 1, Di Liu, Koichi Ito, Masao Maeno, Naoto Suzuki, Masashi Miyazaki Low-intensity Pulsed Ultrasound-Induced ATP Increases Bone Formation via the P2X7 Receptor in Osteoblast-Like MC3T3-E1 Cells FEBS Lett 2015 589(3):310-8 PubMed ID: 25542352 DOI: 10.1016/j.febslet.2014.12.013

9232 Takayuki Umezawa, Peng Chen, Yusuke Tsutsumi, Hisashi Doi, Maki Ashida, Shoichi Suzuki, Keiji Moriyama, Takao Hanawa Calcification of MC3T3-E1 Cells on Titanium and Zirconium Dent Mater J 2015 34(5):713-8 PubMed ID: 26438997 DOI: 10.4012/dmj.2015-018

9245 Anupama R Rajapakshe, Katarzyna A Podyma-Inoue, Kazue Terasawa, Katsuya Hasegawa, Toshimitsu Namba, Yasuhiro Kumei, Masaki Yanagishita, Miki Hara-Yokoyama Lysosome-associated Membrane Proteins (LAMPs) Regulate Intracellular Positioning of Mitochondria in MC3T3-E1 Cells Exp Cell Res 2015 331(1):211-22 PubMed ID: 25246127 DOI: 10.1016/j.yexcr.2014.09.014

9365 Akio Watanabe, Momochika Kumagai, Takashi Mishima, Junya Ito, Yurika Otoki, Teppei Harada, Tsuyoshi Kato, Mikihiko Yoshida, Misora Suzuki, Izumi Yoshida, Kazuhiro Fujita, Masatoshi Watai, Kiyotaka Nakagawa, Teruo Miyazawa Toddaculin, Isolated From of Toddalia Asiatica (L.) Lam., Inhibited Osteoclastogenesis in RAW 264 Cells and Enhanced Osteoblastogenesis in MC3T3-E1 Cells PLoS One 2015 10(5):e0127158 PubMed ID: 25993011 DOI: 10.1371/journal.pone.0127158

9366 Norika Tsuchiya, Daisuke Kodama, Shigemi Goto, Akifumi Togari Shear Stress-Induced Ca(2+) Elevation Is Mediated by Autocrine-Acting Glutamate in Osteoblastic MC3T3-E1 Cells J Pharmacol Sci 2015 127(3):311-8 PubMed ID: 25837928 DOI: 10.1016/j.jphs.2015.01.005

9367 Yoko Karasawa, Hideki Tanaka, Kumiko Nakai, Natsuko Tanabe, Takayuki Kawato, Masao Maeno, Noriyoshi Shimizu Tension Force Downregulates Matrix Metalloproteinase Expression and Upregulates the Expression of Their Inhibitors Through MAPK Signaling Pathways in MC3T3-E1 Cells Int J Med Sci 2015 12(11):905-13 PubMed ID: 26640410 DOI: 10.7150/ijms.13263

9368 Koichi IMAI, Tsubasa SHIRAI, Hiroki ISHIKAWA, Yoshitomo HONDA, Muneyasu SHIDA, Fumiya OGAWA, Hirofumi SAWAI, Tadashi OHKUBO, Tatsuro MIYAKE, Fumio WATARI Preliminary Experimental Study by the Cell Differentiation and a Cell Viability on the Cell Culture Environment with the Linear Structures of Nylon Fiber Bundles Nano Biomedicine 2015 7:5-10 DOI: 10.11344/nano.7.5

9369 Hirom iHagiwara, Roshan Basnet, Sundari I.Wiyasihati, Kyoko Nakata, Keitaro Hagiwara, Hitoshi Miyazaki, Kaoru Yoshida Carnosic acid inhibits the formation of osteoclasts through attenuation of expression of RANKL PharmaNutrition 2015 3:1-6 DOI: 10.1016/j.phanu.2014.11.003

9370 Sherman Salim, Maretaningtias Dwi Ariani In Vitro and in Vivo Evaluation of Carbonate Apatite-Collagen Scaffolds With Some Cytokines for Bone Tissue Engineering J Indian Prosthodont Soc 2015 15(4):349-55 PubMed ID: 26929539 DOI: 10.4103/0972-4052.171821

9371 Kahoru Takeda, Haruaki Kitagawa, Ririko Tsuboi, Wakako Kiba, Jun-Ichi Sasaki, Mikako Hayashi, Satoshi Imazato Effectiveness of Non-Biodegradable poly(2-hydroxyethyl Methacrylate)-Based Hydrogel Particles as a Fibroblast Growth factor-2 Releasing Carrier Dent Mater 2015 31(11):1406-14 PubMed ID: 26411646 DOI: 10.1016/j.dental.2015.09.007

9372 Takao Hirai, Kenjiro Tanaka 2, Akifumi Togari 1 α1B-Adrenergic Receptor Signaling Controls Circadian Expression of Tnfrsf11b by Regulating Clock Genes in Osteoblasts Biol Open 2015 4(11):1400-9 PubMed ID: 26453621 DOI: 10.1242/bio.012617

9373 Hee Young Yoo, Young Hoon Song, Jeong Hyun Seo, Hyung Joon Cha & Dong Soo Hwang Recombinant mussel coating protein fused with cell adhesion recognition motif enhanced cell proliferation Biotechnology and Bioprocess Engineering 2015 20:211–217 DOI: 10.1007/s12257-014-0621-4

9375 Gyeung Mi Seon , Hyok Jin Seo, Soon Young Kwon, Mi Hee Lee, Byeong-Ju Kwon, Min Sung Kim, Min-Ah Koo, Bong Joo Park, Jong-Chul Park Titanium Surface Modification by Using Microwave-Induced Argon Plasma in Various Conditions to Enhance Osteoblast Biocompatibility Biomater Res 2015 19:13 PubMed ID: 26331083 DOI: 10.1186/s40824-015-0034-2

9378 R Toita, Sunarso, A N Rashid, K Tsuru, K Ishikawa Modulation of the Osteoconductive Property and Immune Response of Poly(ether Ether Ketone) by Modification With Calcium Ions J Mater Chem B 2015 3(44):8738-8746 PubMed ID: 32262731 DOI: 10.1039/c5tb01679g

9380 Chunrong Yang, Cong Fang a b Microporous Nano-hydroxyapatite/collagen/phosphatidylserine Scaffolds Embedding Collagen Microparticles for Controlled Drug Delivery in Bone Tissue Engineering Materials Research 2015 18 DOI: 10.1590/1516-1439.042115

9381 Clarisse Ribeiro, Vitor Sencadas, Anabela C Areias, F Miguel Gama, Senentxu Lanceros-Méndez Surface Roughness Dependent Osteoblast and Fibroblast Response on poly(L-lactide) Films and Electrospun Membranes J Biomed Mater Res A 2015 103(7):2260-8 PubMed ID: 25370449 DOI: 10.1002/jbm.a.35367

9382 Bong-Hyuk Choi, Hogyun Cheong, Jin-Soo Ahn, Cong Zhou, Jong Jin Kwon, Hyung Joon Cha, Sang Ho Jun Engineered Mussel Bioglue as a Functional Osteoinductive Binder for Grafting of Bone Substitute Particles to Accelerate in Vivo Bone Regeneration J Mater Chem B 2015 3(4):546-555 PubMed ID: 32262336 DOI: 10.1039/c4tb01197j

9383 M Hiasa, J Teramachi , A Oda, R Amachi, T Harada, S Nakamura, H Miki, S Fujii, K Kagawa, K Watanabe, I Endo, Y Kuroda, T Yoneda, D Tsuji, M Nakao, E Tanaka, K Hamada, S Sano, K Itoh, T Matsumoto, M Abe Pim-2 Kinase Is an Important Target of Treatment for Tumor Progression and Bone Loss in Myeloma Leukemia 2015 29(1):207-17 PubMed ID: 24787487 DOI: 10.1038/leu.2014.147

9384 Kazi Anisur Rahman, Gulsan Ara Sathi, Hiroaki Taketa, Mahmoud Farahat, Masahiro Okada, Yasuhiro Torii, and Takuya Matsumoto Novel 3D-Printed Device for the Simple Preparation of Hydrogel Beads 3D Printing and Additive Manufacturing 2015 2 DOI: 10.1089/3dp.2014.0023

9385 Ekavianty Prajatelistia Chanoong Lim Dongyeop X. Oh Sang Ho Jun Dong Soo Hwang Chitosan and hydroxyapatite composite cross‐linked by dopamine has improved anisotropic hydroxyapatite growth and wet mechanical properties Eng Life Sci 2015 15: 254-261 DOI: 10.1002/elsc.201400194

9386 Erika NISHIDA, Hirofumi MIYAJI, Junko UMEDA, Katsuyoshi KONDOH, Hiroko TAKITA, Izumi KANAYAMA, Saori TANAKA, Akihito KATO, Bunshi FUGETSU, Tsukasa AKASAKA, Masamitsu KAWANAMI Biological Response to Nanostructure of Carbon Nanotube/titanium Composite Surfaces Nano Biomedicine 2015 7:11-20 DOI: 10.11344/nano.7.11

9387 Takayuki Yamada, Yoichi Ezura, Tadayoshi Hayata, Shuichi Moriya, Jumpei Shirakawa, Takuya Notomi, Smriti Arayal, Makiri Kawasaki, Yayoi Izu, Kiyoshi Harada, Masaki Noda β₂ Adrenergic Receptor Activation Suppresses Bone Morphogenetic Protein (BMP)-induced Alkaline Phosphatase Expression in Osteoblast-Like MC3T3E1 Cells J Cell Biochem 2015 116(6):1144-52 PubMed ID: 25536656 DOI: 10.1002/jcb.25071

9388 Sho Miyamoto, Yoichi Miyamoto, Yo Shibata, Kentaro Yoshimura, Eri Izumida, Hiroaki Suzuki, Takashi Miyazaki, Koutaro Maki, Ryutaro Kamijo In Situ Quasi-Static and Dynamic Nanoindentation Tests on Calcified Nodules Formed by Osteoblasts: Implication of Glucocorticoids Responsible for Osteoblast Calcification Acta Biomater 2015 12:216-226 PubMed ID: 25448350 DOI: 10.1016/j.actbio.2014.10.038

9389 Hyun-Seok Jin, Jeonghyun Kim, Sangwook Park, Eunkuk Park, Bo-Young Kim, Vit-Na Choi, Young-Hyun Yoo, Bom-Taeck Kim, Seon-Yong Jeong Association of the I264T Variant in the Sulfide Quinone Reductase-Like (SQRDL) Gene With Osteoporosis in Korean Postmenopausal Women PLoS One 2015 10(8):e0135285 PubMed ID: 26258864 DOI: 10.1371/journal.pone.0135285

9390 Takuya Notomi, Miyuki Kuno, Akiko Hiyama, Yoichi Ezura, Masashi Honma, Toru Ishizuka, Kiyoshi Ohura, Hiromu Yawo, Masaki Noda Membrane Depolarization Regulates Intracellular RANKL Transport in Non-Excitable Osteoblasts Bone 2015 81:306-314 PubMed ID: 26211991 DOI: 10.1016/j.bone.2015.07.031

9392 Masahiko Terauchi, Go Ikeda, Kei Nishida, Atsushi Tamura, Satoshi Yamaguchi, Kiyoshi Harada, Nobuhiko Yui Supramolecular Polyelectrolyte Complexes of Bone Morphogenetic Protein-2 With Sulfonated Polyrotaxanes to Induce Enhanced Osteogenic Differentiation Macromol Biosci 2015 15(7):953-64 PubMed ID: 25810046 DOI: 10.1002/mabi.201500032

9393 Terukazu Sanui, Urara Tanaka, Takao Fukuda, Kyosuke Toyoda, Takaharu Taketomi, Ryo Atomura, Kensuke Yamamichi, Fusanori Nishimura Mutation of Spry2 Induces Proliferation and Differentiation of Osteoblasts but Inhibits Proliferation of Gingival Epithelial Cells J Cell Biochem 2015 116(4):628-39 PubMed ID: 25399781 DOI: 10.1002/jcb.25014

9395 Işıl Gerçek Beşkardeş, Tuğrul Tolga Demirtaş, Müge Dağlı Durukan, Menemşe Gümüşderelioğlu Microwave-assisted Fabrication of Chitosan-Hydroxyapatite Superporous Hydrogel Composites as Bone Scaffolds J Tissue Eng Regen Med 2015 9(11):1233-46 PubMed ID: 23239627 DOI: 10.1002/term.1677

9396 Naoko Hase, Nobuaki Ozeki, Taiki Hiyama, Hideyuki Yamaguchi, Rie Kawai, Ayami Kondo, Kazuhiko Nakata, Makio Mogi Products of Dentin Matrix protein-1 Degradation by interleukin-1β-induced Matrix metalloproteinase-3 Promote Proliferation of Odontoblastic Cells Biosci Trends 2015 ;9(4):228-36 PubMed ID: 26355224 DOI: 10.5582/bst.2015.01092

9397 Shoichi Kaneshiro, Kosuke Ebina, Kenrin Shi, Kiyoshi Yoshida, Dai Otsuki, Hideki Yoshikawa, Chikahisa Higuchi Bruton Tyrosine Kinase (Btk) Suppresses Osteoblastic Differentiation J Bone Miner Metab 2015 33(5):486-95 PubMed ID: 25230818 DOI: 10.1007/s00774-014-0612-8

9399 Koji Mizuhashi, Taro Chaya, Takashi Kanamoto, Yoshihiro Omori, Takahisa Furukawa Obif, a Transmembrane Protein, Is Required for Bone Mineralization and Spermatogenesis in Mice PLoS Onec 2015 10(7):e0133704 PubMed ID: 26207632 DOI: 10.1371/journal.pone.0133704

9403 Drago Skrtic, Joseph M. Antonucci Dental Composites: Bioactive Polymeric Amorphous Calcium Phosphate-Based Encyclopedia of Biomedical Polymers and Polymeric Biomaterials 2015 2443 DOI: 10.1081/E-EBPP-120051063

9374 Taro Kariya, Natsuko Tanabe, Chieko Shionome, Soichiro Manaka, Takayuki Kawato, Ning Zhao, Masao Maeno, Naoto Suzuki, Noriyoshi Shimizu Tension Force-Induced ATP Promotes Osteogenesis Through P2X7 Receptor in Osteoblasts J Cell Biochem 2015 116(1):12-21 PubMed ID: 24905552 DOI: 10.1002/jcb.24863

9405 Yoshikazu Mikami, Kiyofumi Yamamoto, Yuko Akiyama, Masayuki Kobayashi, Eri Watanabe, Nobukazu Watanabe, Masatake Asano, Noriyoshi Shimizu, Kazuo Komiyama Osteogenic Gene Transcription Is Regulated via Gap Junction-Mediated Cell-Cell Communication Stem Cells Dev 2015 24(2):214-27 PubMed ID: 25137151 DOI: 10.1089/scd.2014.0060

10322 Ryo Nishikiori, Kotaro Watanabe, Koichi Kato Antibody Arrays for Quality Control of Mesenchymal Stem Cells ACS Appl Mater Interfaces 2015 7(30):16828-36 PubMed ID: 26172315 DOI: 10.1021/acsami.5b04860

12560 Eto S, Miyamoto H, Shobuike T, Noda I, Akiyama T, Tsukamoto M, Ueno M, Someya S, Kawano S, Sonohata M, Mawatari M. Silver oxide-containing hydroxyapatite coating supports osteoblast function and enhances implant anchorage strength in rat femur J Orthop Res 2015 33(9):1391-7. PubMed ID: 25808232 DOI: 10.1002/jor.22903

14966 Atsushi Horiguchi, Toshihiko Shiraishi Study on a Cell Mechanosensing System by Measuring Structural Deformation and Biochemical Response Biomedical and Biotechnology Engineering 2015 3 DOI: 10.1115/imece2015-51456

15038 Ivashchenko S, Escobar Ivirico JL, García Cruz DM, Campillo-Fernández A, Gallego Ferrer G, Monleón Pradas M. Bioactive organic-inorganic poly(CLMA-co-HEA)/silica nanocomposites J Biomater Appl 2015 29(8):1096-10 PubMed ID: 25294191 DOI: 10.1177/0885328214554816

15218 Maeda Y, Sekiguchi F, Yamanaka R, Sugimoto R, Yamasoba D, Tomita S, Nishikawa H, Kawabata A. Mechanisms for proteinase-activated receptor 1-triggered prostaglandin E2 generation in mouse osteoblastic MC3T3-E1 cells Biol Chem 2015 396(2):153-62 PubMed ID: 25205726 DOI: 10.1515/hsz-2014-0148

15185 Tomohiro Fukuno, Toshihiko Shiraishi Effects of Cyclic Strain at Focal Adhesions on Migration of an Osteoblast Volume 3: Biomedical and Biotechnology Engineering 2015 DOI: 10.1115/imece2015-51447

17411 Zhou X, Park SH, Mao H, Isoshima T, Wang Y, Ito Y. Nanolayer formation on titanium by phosphonated gelatin for cell adhesion and growth enhancement Int J Nanomedicine 2015 10:5597-607 PubMed ID: 26366080 DOI: 10.2147/IJN.S82166

19400 Erika Nishida, Hirofumi Miyaji, Hiroko Takita, Izumi Kanayama, Maiko Tsuji, Tsukasa Akasaka, Tsutomu Sugaya, Ryuji Sakagami, Masamitsu Kawanami Graphene oxide coating facilitates the bioactivity of scaffold material for tissue engineering Japanese Journal of Applied Physics 2014 53:06JD04 DOI: 10.7567/jjap.53.06jd04

3517 Kosaka T, Fukui R, Matsui M, Kurosaka Y, Nishimura H, Tanabe M, Takakura Y, Iwai K, Waki T, Fujita T. RAGE, receptor of advanced glycation endoproducts, negatively regulates chondrocytes differentiation. PLoS One 2014 9(9):e108819 PubMed ID: 25275461 DOI: 10.1371/journal.pone.0108819

6607 Nakazato R, Takarada T, Watanabe T, Nguyen BT, Ikeno S, Hinoi E, Yoneda Y. Constitutive and functional expression of runt-related transcription factor-2 by microglial cells. Neurochem Int 2014 74:24-35 PubMed ID: 24768841 DOI: 10.1016/j.neuint.2014.04.010

6609 Yang YJ, Kwon Y, Choi BH, Jung D, Seo JH, Lee KH, Cha HJ. Multifunctional adhesive silk fibroin with blending of RGD-bioconjugated mussel adhesive protein. Biomacromolecules 2014 15(4):1390-8 PubMed ID: 24601579 DOI: 10.1021/bm500001n

6611 Lin YY, Chen CY, Chuang TY, Lin Y, Liu HY, Mersmann HJ, Wu SC, Ding ST. Adiponectin receptor 1 regulates bone formation and osteoblast differentiation by GSK-3β/β-catenin signaling in mice. Bone 2014 64:147-54 PubMed ID: 24713193 DOI: 10.1016/j.bone.2014.03.051

9294 Yaqiong Yu, Di Yang, Lihong Qiu, Hirohiko Okamura, Jiajie Guo, Tatsuji Haneji Tumor Necrosis Factor-α Induces interleukin-34 Expression Through Nuclear factor‑κB Activation in MC3T3-E1 Osteoblastic Cells Mol Med Rep 2014 10(3):1371-6 PubMed ID: 24970360 DOI: 10.3892/mmr.2014.2353

9295 Eiichi Suzuki, Hiromi Ochiai-Shino, Hideto Aoki, Shoko Onodera, Akiko Saito, Atsushi Saito, Toshifumi Azuma Akt Activation Is Required for TGF-β1-induced Osteoblast Differentiation of MC3T3-E1 Pre-Osteoblasts PLoS One 2014 9(12):e112566 PubMed ID: 25470129 DOI: 10.1371/journal.pone.0112566

9296 Naofumi Ohtsu, Mitsuhiro Hirano, Hirofumi Arai Response of Osteoblast-Like MC3T3-E1 Cells on Bioactive Titanium Fabricated by a Chemical Treatment Process Using a Calcium-Phosphate Slurry J Biomed Mater Res A 2014 102(11):3838-45 PubMed ID: 24307316 DOI: 10.1002/jbm.a.35053

9297 Chihiro Mochizuki, Hiroki Hara, Kei Oya, Shun Aoki, Tohru Hayakawa, Hiromichi Fujie, Mitsunobu Sato Behaviors of MC3T3-E1 Cells on Carbonated Apatite Films, With a Characteristic Network Structure, Fabricated on a Titanium Plate by Aqueous Spray Coating Mater Sci Eng C Mater Biol Appl 2014 39:245-52 PubMed ID: 24863222 DOI: 10.1016/j.msec.2014.02.040

9298 Emina Aoyama, Ippei Watari 1, Katarzyna Anna Podyma-Inoue 2, Masaki Yanagishita 2, Takashi Ono 1 Expression of Glucagon-Like peptide-1 Receptor and Glucose‑dependent Insulinotropic Polypeptide Receptor Is Regulated by the Glucose Concentration in Mouse Osteoblastic MC3T3-E1 Cells Int J Mol Med 2014 34(2):475-82 PubMed ID: 24866833 DOI: 10.3892/ijmm.2014.1787

9299 Muhammad Hanif Siddiqi, Muhammad Zubair Siddiqi, Sungeun Ahn, Sera Kang, Yeon-Ju Kim, Karpagam Veerappan, Dong-Uk Yang, Deok-Chun Yang Stimulative Effect of Ginsenosides Rg5:Rk1 on Murine Osteoblastic MC3T3-E1 Cells Phytother Res 2014 28(10):1447-55 PubMed ID: 24643957 DOI: 10.1002/ptr.5146

9300 Yoko Nakamura, Ai Hasebe, Kaneyoshi Takahashi, Masumi Iijima, Nobuo Yoshimoto, Andrés D Maturana, Kang Ting, Shun'ichi Kuroda, Tomoaki Niimi Oligomerization-induced Conformational Change in the C-terminal Region of Nel-like Molecule 1 (NELL1) Protein Is Necessary for the Efficient Mediation of Murine MC3T3-E1 Cell Adhesion and Spreading J Biol Chem 2014 289(14):9781-94 PubMed ID: 24563467 DOI: 10.1074/jbc.M113.507020

9301 Chethala N Vishnuprasad 1, Tomoko Tsuchiya 2, Shiro Kanegasaki 1, Joon Ho Kim 1, Sung Soo Han 1 Aurantio-obtusin Stimulates Chemotactic Migration and Differentiation of MC3T3-E1 Osteoblast Cells Planta Med 2014 80(7):544-9 PubMed ID: 24841966 DOI: 10.1055/s-0034-1368445

9302 Eun Mi Choi Sunflower seed extract enhances the differentiation of osteoblastic MC3T3-E1 cells Food and Agricultural Immunology 2014 25:9-19 DOI: 10.1080/09540105.2012.716399

9303 Kyung-Mi Chang, Eun-Mi Choi & Gun-Hee Kim Effects of medicinal plant Atractylodes japonica on MC3T3-E1 cells Food Science and Biotechnology 2014 23:1173–1176 DOI: 10.1007/s10068-014-0160-y

9304 Kaori Tsutsumi, Nagahito Saito, Yumi Kawazoe, Hong-Kean Ooi, Toshikazu Shiba Morphogenetic Study on the Maturation of Osteoblastic Cell as Induced by Inorganic Polyphosphate PLoS One 2014 9(2):e86834 PubMed ID: 24498284 DOI: 10.1371/journal.pone.0086834

9305 Miki Nakamura-Ota, Ryoji Hamanaka, Hiroyuki Yano, Sawako Adachi, Hideaki Sumiyoshi, Noritaka Matsuo, Hidekatsu Yoshioka A New Murine Osteoblastic Cell Line Immortalized With the SV40 Large T Antigen Cell Tissue Bank 2014 15(3):373-80 PubMed ID: 23974965 DOI: 10.1007/s10561-013-9394-9

9306 Naofumi Ohtsu, Toyofumi Takahara, Mitsuhiro Hirano, Hirofumi Arai Effect of treatment temperature on the biocompatibility and mechanical strength of hydroxyapatite coating formed on titanium using calcium phosphate slurry Surface and Coatings Technology 2014 239:185-190 DOI: 10.1016/j.surfcoat.2013.11.038

9307 Dajana Milovac, Tatiana C Gamboa-Martínez, Marica Ivankovic, Gloria Gallego Ferrer, Hrvoje Ivankovic PCL-coated Hydroxyapatite Scaffold Derived From Cuttlefish Bone: In Vitro Cell Culture Studies Mater Sci Eng C Mater Biol Appl 2014 42:264-72 PubMed ID: 25063118 DOI: 10.1016/j.msec.2014.05.034

9308 Mitsuhiro Hirano, Taro Kozuka, Yuta Asano, Yuko Kakuchi, Hirofumi Arai, Naofumi Ohtsu Effect of sterilization and water rinsing on cell adhesion to titanium surfaces Applied Surface Science 2014 311:498-502 DOI: 10.1016/j.apsusc.2014.05.096

9309 Takao Hirai, Kenjiro Tanaka, Akifumi Togari β-Adrenergic Receptor Signaling Regulates Ptgs2 by Driving Circadian Gene Expression in Osteoblasts J Cell Sci 2014 127(Pt 17):3711-9 PubMed ID: 24994935 DOI: 10.1242/jcs.148148

9310 Erika Nishida, Hirofumi Miyaji, Hiroko Takita, Izumi Kanayama, Maiko Tsuji, Tsukasa Akasaka, Tsutomu Sugaya, Ryuji Sakagami and Masamitsu Kawanami Graphene oxide coating facilitates the bioactivity of scaffold material for tissue engineering Japanese Journal of Applied Physics 2014 53:06JD04

9311 Meiko Tachikake-Kuramoto, Junji Suzuki, Yurong Wangb Chieko Mitsuhata, Katsuyuki Kozai Lipopolysaccharide derived from Aggregatibacter actinomycetemcomitans inhibits differentiation of osteoblasts Pediatric Dental Journal 2014 24:83-88 DOI: 10.1016/j.pdj.2014.03.004

9312 Geunseon Ahn, Yunna Kim, Sang-Won Lee, Yoon Jeong Jeong, Hyungbin Son & Donghyun Lee Effect of heterogeneous multi-layered gelatin scaffolds on the diffusion characteristics and cellular activities of preosteoblasts Macromolecular Research 2014 22:99–107 DOI: 10.1007/s13233-014-2024-y

9313 Naofumi Ohtsu, Wataru Saito, Misao Yamane Selectable surface nitridation of titanium using focused pulsed Nd: YAG laser irradiation with nitrogen gas blow Surface and Coatings Technology 2014 246:52-56 DOI: 10.1016/j.surfcoat.2014.02.068

9314 D. M. Correiaab, R. Gonçalvesab, C. Ribeiroac, V. Sencadasad, G. Botelhob, J. L. Gomez Ribellesef and S. Lanceros-Méndez Electrosprayed poly (vinylidene fluoride) microparticles for tissue engineering applications RSC Adv 2014 4:33013-33021 DOI: 10.1039/C4RA04581E

9315 Takao Hirai, Kenjiro Tanaka, Akifumi Togari α1-adrenergic Receptor Signaling in Osteoblasts Regulates Clock Genes and Bone Morphogenetic Protein 4 Expression Through Up-Regulation of the Transcriptional Factor Nuclear Factor IL-3 (Nfil3)/E4 Promoter-Binding Protein 4 (E4BP4) J Biol Chem 2014 289(24):17174-83 PubMed ID: 24794868 DOI: 10.1074/jbc.M113.546135

9316 Izumi Kanayama, Hirofumi Miyaji, Hiroko Takita, Erika Nishida, Maiko Tsuji, Bunshi Fugetsu, Ling Sun, Kana Inoue, Asako Ibara, Tsukasa Akasaka, Tsutomu Sugaya, Masamitsu Kawanami Comparative Study of Bioactivity of Collagen Scaffolds Coated With Graphene Oxide and Reduced Graphene Oxide Int J Nanomedicine 2014 9:3363-73 PubMed ID: 25050063 DOI: 10.2147/IJN.S62342

9317 Daniela M. Correia Clarisse Ribeiro José C.C. Ferreira Gabriela Botelho José Luis Gomez Ribelles Senentxu Lanceros‐Méndez Vitor Sencadas Influence of electrospinning parameters on poly (hydroxybutyrate) electrospun membranes fiber size and distribution Advanced Science 2014 54:1608-1617 DOI: 10.1002/pen.23704

9318 Shoichi Kaneshiro, Kosuke Ebina, Kenrin Shi, Chikahisa Higuchi, Makoto Hirao, Michio Okamoto, Kota Koizumi, Tokimitsu Morimoto, Hideki Yoshikawa, Jun Hashimoto IL-6 Negatively Regulates Osteoblast Differentiation Through the SHP2/MEK2 and SHP2/Akt2 Pathways in Vitro J Bone Miner Metab 2014 32(4):378-92 PubMed ID: 24122251 DOI: 10.1007/s00774-013-0514-1

9319 Keiko Kaneko, Chikahisa Higuchi 1, Norifumi Naka 1, Hideki Yoshikawa Expression of Noggin, an Antagonist of Bone Morphogenetic Protein, in Schwannoma: A Possible Mechanism Oncol Lett 2014 8(1):111-116 PubMed ID: 24959229 DOI: 10.3892/ol.2014.2138

9320 Yuko Akiyama, Yoshikazu Mikami, Eri Watanabe, Nobukazu Watanabe, Taku Toriumi, Tomihisa Takahashi, Kazuo Komiyama, Keitaro Isokawa, Noriyoshi Shimizu, Masaki J Honda The P75 Neurotrophin Receptor Regulates Proliferation of the Human MG63 Osteoblast Cell Line Differentiation 2014 87(3-4):111-8 PubMed ID: 24582280 DOI: 10.1016/j.diff.2014.01.002

9321 Juna Nakao, Yasuyuki Fujii, Joji Kusuyama, Kenjiro Bandow, Kyoko Kakimoto, Tomokazu Ohnishi, Tetsuya Matsuguchi Low-intensity Pulsed Ultrasound (LIPUS) Inhibits LPS-induced Inflammatory Responses of Osteoblasts Through TLR4-MyD88 Dissociation Bone 2014 58:17-25 PubMed ID: 24091132 DOI: 10.1016/j.bone.2013.09.018

9322 Tomohiro Itoh, Masahiro Nakamura, Hirohisa Nakamichi, Masashi Ando, Yasuyuki Tsukamasa, Yukio Furuichi Regulation of the Differentiation of Osteoblasts and Osteoclasts by a Hot-Water Extract of Adzuki Beans (Vigna Angularis) Biosci Biotechnol Biochem 2014 78(1):92-9 PubMed ID: 25036490 DOI: 10.1080/09168451.2014.877182

9323 Ran Zhao, Masayoshi Kamon, Kazuichi Sakamoto (–)-Epigallocatechingallate Interferes RANKL/RANK Signal Pathway and Induces Apoptosis during Osteoclastogenesis in RAW264 Cell Food and Nutrition Sciences 2014 5:107-116 DOI: 10.4236/fns.2014.52014

9324 Nobuaki Ozeki, Rie Kawai, Hideyuki Yamaguchi, Taiki Hiyama, Katsue Kinoshita, Naoko Hase, Kazuhiko Nakata, Ayami Kondo, Makio Mogi, Hiroshi Nakamura IL-1β-induced Matrix metalloproteinase-13 Is Activated by a Disintegrin and metalloprotease-28-regulated Proliferation of Human Osteoblast-Like Cells Exp Cell Res 2014 ;323(1):165-77 PubMed ID: 24613731 DOI: 10.1016/j.yexcr.2014.02.018

9325 Hany Mohamed Khattab, Mitsuaki Ono, Wataru Sonoyama, Yasutaka Oida, Shigehiko Shinkawa, Yuya Yoshioka, Kenji Maekawa, Yasuhiko Tabata, Kazushige Sugama, Walter Sebald, Takuo Kuboki The BMP2 Antagonist Inhibitor L51P Enhances the Osteogenic Potential of BMP2 by Simultaneous and Delayed Synergism Bone 2014 69:165-73 PubMed ID: 25240457 DOI: 10.1016/j.bone.2014.09.011

9326 A. C. Lopes, C. Ribeiro, V. Sencadas, G. Botelho & S. Lanceros-Méndez Effect of filler content on morphology and physical–chemical characteristics of poly (vinylidene fluoride)/NaY zeolite-filled membranes Journal of Materials Science 2014 49:3361–3370 DOI: 10.1007/s10853-014-8043-4

9327 Tsai-Ching Yang, Hui-Ying Shu, Hsien-Te Chen, Chi-Jen Chung, Ju-LiangH Interface between grown osteoblast and micro-arc oxidized bioactive layers Surface and Coatings Technology 2014 259:185-192 DOI: 10.1016/j.surfcoat.2014.04.002

9328 Byeong-Ju Kwon, Mi Hee Lee, Min-Ah Koo, Jae-Jin Han, Jong-Chul Park Ethyl-3,4-dihydroxybenzoate With a Dual Function of Induction of Osteogenic Differentiation and Inhibition of Osteoclast Differentiation for Bone Tissue Engineering Tissue Eng Part A 2014 20(21-22):2975-84 PubMed ID: 24784993 DOI: 10.1089/ten.TEA.2013.0567

9330 Xin Li, Jamie Garcia, Jinxiu Lu, Sidney Iriana, Ivo Kalajzic, David Rowe, Linda L Demer, Yin Tintut Roles of Parathyroid Hormone (PTH) Receptor and Reactive Oxygen Species in Hyperlipidemia-Induced PTH Resistance in Preosteoblasts J Cell Biochem 2014 115(1):179-88 PubMed ID: 24038594 DOI: 10.1002/jcb.24648

9331 Masanobu Kamitakahara, Yuika Uno, Koji Ioku Behavior of Osteoblast-Like Cells on Calcium-Deficient Hydroxyapatite Ceramics Composed of Particles With Different Shapes and Sizes J Mater Sci Mater Med 2014 25(1):239-45 PubMed ID: 24101185 DOI: 10.1007/s10856-013-5063-6

9332 Joji Kusuyama, Kenjiro Bandow, Mitsuo Shamoto, Kyoko Kakimoto, Tomokazu Ohnishi, Tetsuya Matsuguchi Low Intensity Pulsed Ultrasound (LIPUS) Influences the Multilineage Differentiation of Mesenchymal Stem and Progenitor Cell Lines Through ROCK-Cot/Tpl2-MEK-ERK Signaling Pathway J Biol Chem 2014 289(15):10330-44 PubMed ID: 24550383 DOI: 10.1074/jbc.M113.546382

9333 Yun Kee Jo, Jeong Hyun Seo, Bong-Hyuk Choi, Bum Jin Kim, Hwa Hui Shin, Byeong Hee Hwang, Hyung Joon Cha Surface-independent Antibacterial Coating Using Silver Nanoparticle-Generating Engineered Mussel Glue ACS Appl Mater Interfaces 2014 6(22):20242-53 PubMed ID: 25311392 DOI: 10.1021/am505784k

9334 Tetsuro Ohba, Heather A Cole, Justin M M Cates, David A Slosky, Hirotaka Haro, Takashi Ando, Herbert S Schwartz, Jonathan G Schoenecker Bisphosphonates Inhibit Osteosarcoma-Mediated Osteolysis via Attenuation of Tumor Expression of MCP-1 and RANKL J Bone Miner Res 2014 29(6):1431-45 PubMed ID: 24443409 DOI: 10.1002/jbmr.2182

9335 Takuya Notomi, Ikuaki Karasaki, Yuichi Okazaki, Nobukazu Okimoto, Yushi Kato, Kiyoshi Ohura, Masaki Noda, Toshitaka Nakamura, Masashige Suzuki Insulinogenic Sucrose+amino Acid Mixture Ingestion Immediately After Resistance Exercise Has an Anabolic Effect on Bone Compared With Non-Insulinogenic Fructose+amino Acid Mixture in Growing Rats Bone 2014 65:42-8 PubMed ID: 24815919 DOI: 10.1016/j.bone.2014.05.002

9337 C. S. R. Silva,G. M. Luz,T. C. Gamboa-martÍnez,J. F. Mano,J. L. GÓmez ribelles &J. A. GÓmez-tejedorCenter for Biomaterials and T Poly (ɛ-caprolactone) electrospun scaffolds filled with nanoparticles. Production and optimization according to Taguchi's methodology Journal of Macromolecular Science, Part B 2014 53:781-799 DOI: 10.1080/00222348.2013.861304

9338 Miho Nakamura, Akira Kobayashi, Kosuke Nozaki, Naohiro Horiuchi, Akiko Nagai1, Kimihiro Yamashita Improvement of osteoblast adhesion through polarization of plasma-sprayed hydroxyapatite coatings on metal Journal of Medical and Biological Engineering 2014 34(1): 44-48

9339 Nobuaki Ozeki, Makio Mogi, Hideyuki Yamaguchi, Taiki Hiyama, Rie Kawai, Naoko Hase, Kazuhiko Nakata, Hiroshi Nakamura, Randall H Kramer Differentiation of Human Skeletal Muscle Stem Cells Into Odontoblasts Is Dependent on Induction of α1 Integrin Expression J Biol Chem 2014 289(20):14380-91 PubMed ID: 24692545 DOI: 10.1074/jbc.M113.526772

9340 Shigeki Suzuki, Seiji Kobuke, Naoto Haruyama, Hiroaki Hoshino, Ashok B Kulkarni, Fusanori Nishimura Adhesive and Migratory Effects of Phosphophoryn Are Modulated by Flanking Peptides of the Integrin Binding Motif PLoS One 2014 9(11):e112490 PubMed ID: 25396425 DOI: 10.1371/journal.pone.0112490

9341 Ji-Won Lee, Akira Yamaguchi, Tadahiro Iimura Functional Heterogeneity of Osteocytes in FGF23 Production: The Possible Involvement of DMP1 as a Direct Negative Regulator Bonekey Rep 2014 3:543 PubMed ID: 24991406 DOI: 10.1038/bonekey.2014.38

9342 Naofumi Shiomi, Keiko Watanabe Effects of hydrocortisone, glycerophosphate and retinol on the differentiation of mesenchymal stem cells and vascular endothelial cells to osteoblasts Journal of Biomedical Science and Engineering 2014 7:Article ID:51519 DOI: 10.4236/jbise.2014.713103

9355 Muhammad Hanif Siddiqi, Muhammad Zubair Siddiqi, Sungeun Ahn, Yeon-Ju Kim, Deok Chun Yang Ginsenoside Rh1 Induces Mouse Osteoblast Growth and Differentiation Through the Bone Morphogenetic Protein 2/runt-related Gene 2 Signalling Pathway J Pharm Pharmacol 2014 66(12):1763-73 PubMed ID: 25154440 DOI: 10.1111/jphp.12306

15318 Guo J, Yang D, Okamura H, Teramachi J, Ochiai K, Qiu L, Haneji T. Calcium hydroxide suppresses Porphyromonas endodontalis lipopolysaccharide-induced bone destruction J Dent Res 2014 93(5):508-13 PubMed ID: 24603641 DOI: 10.1177/0022034514526886

15475 Chunrong Yang, Jianhua Wang Preparation and characterization of collagen microspheres for sustained release of steroidal saponins Materials Research 2014 17:1644-1650 DOI: 10.1590/1516-1439.307214

15476 Toshihiko Shiraishi, Akinori Ishii, Shin Morishita Effects of Mechanical Vibration on Multilayering of Cultured Osteoblasts Biomedical and Biotechnology Engineering 2014 3 DOI: 10.1115/imece2014-37731

17409 Kaneko H, Sasaki H, Honma S, Hayakawa T, Sato M, Yajima Y, Yoshinari M. Influence of thin carbonate-containing apatite coating with molecular precursor method to Dent Mater J 2014 33(1):39-47 PubMed ID: 24492110 DOI: 10.4012/dmj.2013-122

17410 Park E, Jin HS, Cho DY, Kim J, Kim MC, Choi CW, Jin Y, Lee JW, Park JH, Chung YS, Huh D, Jeong SY. The effect of Lycii Radicis Cortex extract on bone formation in vitro and in vivo Molecules 2014 19(12):19594-609 PubMed ID: 25432011 DOI: 10.3390/molecules191219594

17407 Suzaki A, Komine-Aizawa S, Hayakawa S. Suppression of osteoblast Toll-like receptor 2 signaling by endothelin-1 J Orthop Res 2014 32(7):910-4. PubMed ID: 24700498 DOI: 10.1002/jor.22627

7649 Watanabe K, Tsunoda K, Itoh M, Fukui M, Mori H, Hitomi K. Transglutaminase 2 and Factor XIII catalyze distinct substrates in differentiating osteoblastic cell line: utility of highly reactive substrate peptides. Amino Acids 2013 44:209-14 PubMed ID: 22045386 DOI: 10.1007/s00726-011-1131-8

7686 Choi EM. Deoxyactein stimulates osteoblast function and inhibits bone-resorbing mediators in MC3T3-E1 cells. J Appl Toxicol 2013 33:190-5 PubMed ID: 21910134 DOI: 10.1002/jat.1733

19362 Ghorbanian L, Emadi R, Razavi SM, Shin H, Teimouri A. Fabrication and characterization of novel diopside/silk fibroin nanocomposite scaffolds for potential application in maxillofacial bone regeneration Int J Biol Macromol 2013 58:275-80 PubMed ID: 23603246 DOI: 10.1016/j.ijbiomac.2013.04.004

5326 Hagihara K, Fujii K, Matsugaki A, Nakano T. Possibility of Mg- and Ca-based intermetallic compounds as new biodegradable implant materials. Mater Sci Eng C Mater Biol Appl 2013 33(7):4101-11 PubMed ID: 23910320 DOI: 10.1016/j.msec.2013.05.055

6206 Ozeki N, Mogi M, Kawai R, Yamaguchi H, Hiyama T, Nakata K, Nakamura H. Mouse-induced pluripotent stem cells differentiate into odontoblast-like cells with induction of altered adhesive and migratory phenotype of integrin. PLoS One 2013 8(11):e80026 PubMed ID: 24244598 DOI: 10.1371/journal.pone.0080026

6322 Tsukamoto T, Li X, Morita H, Minowa T, Aizawa T, Hanagata N, Demura M. Role of S-palmitoylation on IFITM5 for the interaction with FKBP11 in osteoblast cells. PLoS One 2013 8(9):e75831 PubMed ID: 24058703 DOI: 10.1371/journal.pone.0075831

6560 Mitani K1 Haruyama N, Hatakeyama J, Igarashi K. Amelogenin splice isoforms stimulate chondrogenic differentiation of ATDC5 cells. Oral Dis 2013 19(2):169-79 PubMed ID: 22863294 DOI: 10.1111/j.1601-0825.2012.01967.x

6561 Morimoto H, Baba R, Haneji T, Doi Y. Double-stranded RNA-dependent protein kinase regulates insulin-stimulated chondrogenesis in mouse clonal chondrogenic cells, ATDC-5. Cell Tissue Res 2013 351(1):41-7 PubMed ID: 23180319 DOI: 10.1007/s00441-012-1521-6

9253 Yoshiaki Tabuchi, Yuuki Sugahara, Mika Ikegame, Nobuo Suzuki, Kei-ichiro Kitamura, Takashi Kondo Genes Responsive to Low-Intensity Pulsed Ultrasound in MC3T3-E1 Preosteoblast Cells Int J Mol Sci 2013 14(11):22721-40 PubMed ID: 24252911 DOI: 10.3390/ijms141122721

9255 Osamu Ishibashi Bone Morphogenetic Protein-2 Desensitizes MC3T3-E1 Osteoblastic Cells to Estrogen Through Transcriptional Downregulation of Estrogen Receptor 1 J Bone Metab 2013 20(2):83-8 PubMed ID: 24524062 DOI: 10.11005/jbm.2013.20.2.83

9256 Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo Micromorphological Cellular Responses of MC3T3-E1 and RAW264.7 After Exposure to Water-Dispersible Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds Dent Mater J 2013 32(5):725-33 PubMed ID: 24088827 DOI: 10.4012/dmj.2012-203

9257 Yoshimitsu Okazaki, Emiko Gotoh Metal Ion Effects on Different Types of Cell Line, Metal Ion Incorporation Into L929 and MC3T3-E1 Cells, and Activation of Macrophage-Like J774.1 Cells Mater Sci Eng C Mater Biol Appl 2013 33(4):1993-2001 PubMed ID: 23498224 DOI: 10.1016/j.msec.2013.01.015

9258 Yuu Horikiri, Tsuyoshi Shimo, Naito Kurio, Tatsuo Okui, Kenichi Matsumoto, Masahiro Iwamoto, Akira Sasaki Sonic Hedgehog Regulates Osteoblast Function by Focal Adhesion Kinase Signaling in the Process of Fracture Healing PLoS One 2013 8(10):e76785 PubMed ID: 24124594 DOI: 10.1371/journal.pone.0076785

9259 Guy Eelen, Lieve Verlinden, Mark B Meyer, Rik Gijsbers, J Wesley Pike, Roger Bouillon, Annemieke Verstuyf 1,25-Dihydroxyvitamin D3 and the Aging-Related Forkhead Box O and Sestrin Proteins in Osteoblasts J Steroid Biochem Mol Biol 2013 136:112-9 PubMed ID: 22989484 DOI: 10.1016/j.jsbmb.2012.09.011

9261 Lieve Verlinden, Carsten Kriebitzsch, Guy Eelen, Mark Van Camp, Carlien Leyssens, Biauw Keng Tan, Ine Beullens, Annemieke Verstuyf The Odd-Skipped Related Genes Osr1 and Osr2 Are Induced by 1,25-dihydroxyvitamin D3 J Steroid Biochem Mol Biol 2013 136:94-7 PubMed ID: 23238298 DOI: 10.1016/j.jsbmb.2012.12.001

9262 Song Chen, Nobutaka Hanagata Directing osteoblast alignment and elongation on the micro-grooved silica-based hybrid membrane Advanced Materials Research 2013 647:165-169 DOI: 10.4028/www.scientific.net/AMR.647.165

9263 Geunseon Ahn, Jae YeonLee, Dai-WuSeol, Sung Gyu Pyo, DonghyunLee The effect of calcium phosphate cement–silica composite materials on proliferation and differentiation of pre-osteoblast cells Materials Letters 2013 109:302-305 DOI: 10.1016/j.matlet.2013.07.110

9264 Kazuyoshi Uchihashi, Shigehisa Aoki, Aki Matsunobu, Shuji Toda Osteoblast Migration Into Type I Collagen Gel and Differentiation to Osteocyte-Like Cells Within a Self-Produced Mineralized Matrix: A Novel System for Analyzing Differentiation From Osteoblast to Osteocyte Bone 2013 52(1):102-10 PubMed ID: 22985890 DOI: 10.1016/j.bone.2012.09.001

9265 Yohei Hanazaki, Daisuke Ito, Kazuya Furusawa, Akimasa Fukui & Naoki Sasaki Change in the viscoelastic properties of agarose gel by HAp precipitation by osteoblasts cultured in an agarose gel matrix Journal of Biorheology 2013 26:21–28 DOI: 10.1007/s12573-011-0043-2

9266 R. Seda Tığlı Aydın, Baki Hazer, Merve Acar & Menemşe Gümüşderelioğlu Osteogenic activities of polymeric soybean oil-g-polystyrene membranes Polymer Bulletin 2013 70:2065–2082 DOI: 10.1007/s00289-013-0976-2

9267 Maretaningtias Dwi Ariani, Ayumu Matsuura, Isao Hirata, Takayasu Kubo, Koichi Kato, Yasumasa Akagawa New Development of Carbonate Apatite-Chitosan Scaffold Based on Lyophilization Technique for Bone Tissue Engineering Dent Mater J 2013 32(2):317-25 PubMed ID: 23538769 DOI: 10.4012/dmj.2012-257

9268 M Onishi, Y Fujita, H Yoshikawa, T Yamashita Inhibition of Rac1 Promotes BMP-2-induced Osteoblastic Differentiation Cell Death Dis 2013 4(6):e698 PubMed ID: 23807227 DOI: 10.1038/cddis.2013.226

9269 Le Thi　Bang, Kanji Tsuru, Melvin Munar, Kunio Ishikawa, Radzali Othman Mechanical behavior and cell response of PCL coated α-TCP foam for cancellous-type bone replacement Ceramics International 2013 39:5631-5637 DOI: 10.1016/j.ceramint.2012.12.079

9270 Hsien-Te Chen, Chi-Jen Chung, Tsai-Ching Yang, Chin-Hsin Tang, Ju-Liang He Microscopic observations of osteoblast growth on micro-arc oxidized β titanium Applied Surface Science 2013 266:73-80 DOI: 10.1016/j.apsusc.2012.11.087

9272 Song Chen, Xuetao Shi, Shanmugavel Chinnathambi, Hongkai Wu, Nobutaka Hanagata Generation of Microgrooved Silica Nanotube Membranes With Sustained Drug Delivery and Cell Contact Guidance Ability by Using a Teflon Microfluidic Chip Sci Technol Adv Mater 2013 14(1):015005 PubMed ID: 27877563 DOI: 10.1088/1468-6996/14/1/015005

9273 Marco Piola, Monica Soncini, Marco Cantini, Nasser Sadr, Giulio Ferrario, Gianfranco B Fiore Design and Functional Testing of a Multichamber Perfusion Platform for Three-Dimensional Scaffolds ScientificWorldJournal 2013 23:123974. PubMed ID: 24453787 DOI: 10.1155/2013/123974

9274 Kyu-Oh Kim, Byoung-Suhk Kim, Ki-Hoon Lee, Young-Hwan Park, Ick-Soo Kim Osteoblastic Cells Culture on Electrospun Poly(ε-Caprolacton) Scaffolds Incorporating Amphiphilic PEG-POSS Telechelic J Mater Sci Mater Med 2013 24(8):2029-36 PubMed ID: 23661256 DOI: 10.1007/s10856-013-4943-0

9275 Chunrong　Yang, Yuli Li, Kaihui Nan Biologically inspired growth of hydroxyapatite crystals on bio-organics-defined scaffolds Materials Research Bulletin 2013 48:1128-1131 DOI: 10.1016/j.materresbull.2012.12.005

9354 Yasuhiko Abe, Yohei Okazaki, Kyou Hiasa, Keisuke Yasuda, Keisuke Nogami, Wataru Mizumachi, Isao Hirata Bioactive Surface Modification of Hydroxyapatite Biomed Res Int 2013 2013:626452 PubMed ID: 23862150 DOI: 10.1155/2013/626452

9277 Hiroshi Ito, Hodaka Sasaki, Kensuke Saito, Shinya Honma, Yasutomo Yajima, Masao Yoshinari Response of Osteoblast-Like Cells to Zirconia With Different Surface Topography Dent Mater J 2013 32(1):122-9 PubMed ID: 23370880 DOI: 10.4012/dmj.2012-208

9278 Shingen Nakamura, Hirokazu Miki, Shinsuke Kido, Ayako Nakano, Masahiro Hiasa, Asuka Oda, Hiroe Amou, Keiichiro Watanabe, Takeshi Harada, Shiro Fujii, Kyoko Takeuchi, Kumiko Kagawa, Shuji Ozaki, Toshio Matsumoto, Masahiro Abe Activating Transcription Factor 4, an ER Stress Mediator, Is Required For, but Excessive ER Stress Suppresses Osteoblastogenesis by Bortezomib Int J Hematol 2013 98(1):66-73 PubMed ID: 23708974 DOI: 10.1007/s12185-013-1367-z

9279 Yujiro Maeda, Hironori Hojo, Nobuyuki Shimohata, Sungjin Choi, Kenichi Yamamoto, Tsuyoshi Takato, Ung-il Chung, Shinsuke Ohba Bone Healing by Sterilizable Calcium Phosphate Tetrapods Eluting Osteogenic Molecules Biomaterials 2013 34(22):5530-7 PubMed ID: 23623228 DOI: 10.1016/j.biomaterials.2013.03.089

9280 Yuya Yoneyama, Tomonori Matsuno, Yoshiya Hashimoto, Tazuko Satoh In Vitro Evaluation of H2O2 Hydrothermal Treatment of Aged Titanium Surface to Enhance Biofunctional Activity Dent Mater J 2013 32(1):115-21 PubMed ID: 23370879 DOI: 10.4012/dmj.2012-087

9281 Akiyoshi Hoshino, Satoshi Ueha, Sanshiro Hanada, Toshio Imai, Masako Ito, Kenji Yamamoto, Kouji Matsushima, Akira Yamaguchi, Tadahiro Iimura Roles of Chemokine Receptor CX3CR1 in Maintaining Murine Bone Homeostasis Through the Regulation of Both Osteoblasts and Osteoclasts J Cell Sci 2013 126(Pt 4):1032-45 PubMed ID: 23264747 DOI: 10.1242/jcs.113910

9282 Hirohiko Okamura, Kaya Yoshida, Di Yang, Tatsuji Haneji Protein Phosphatase 2A Cα Regulates Osteoblast Differentiation and the Expressions of Bone Sialoprotein and Osteocalcin via Osterix Transcription Factor J Cell Physiol 2013 228(5):1031-7 PubMed ID: 23042641 DOI: 10.1002/jcp.24250

9283 Takanori Kawano 1, Widyasri Prananingrum, Yuichi Ishida 1, Takaharu Goto 1, Yoshihito Naito 1, Megumi Watanabe 1, Yoritoki Tomotake 1, Tetsuo Ichikawa 1 Blue-violet Laser Modification of Titania Treated Titanium: Antibacterial and Osteo-Inductive Effects PLoS One 2013 8(12):e84327 PubMed ID: 24358355 DOI: 10.1371/journal.pone.0084327

9284 Takanori Eguchi, Ken Watanabe, Emilio Satoshi Hara, Mitsuaki Ono, Takuo Kuboki, Stuart K Calderwood OstemiR: A Novel Panel of microRNA Biomarkers in Osteoblastic and Osteocytic Differentiation From Mesencymal Stem Cells PLoS One 2013 8(3):e58796 PubMed ID: 23533592 DOI: 10.1371/journal.pone.0058796

9356 Chunxia Gao Qiang Gao Yadong Li Mohamed N. Rahaman Akira Teramoto Koji Abe In vitro evaluation of electrospun gelatin‐bioactive glass hybrid scaffolds for bone regeneration The Journal of Applied Polymer Science 2013 127:2588-2599 DOI: 10.1002/app.37946

9276 Kazuyuki Furuya, Noriko Yamamoto, Yuki Ohyabu, Teruyuki Morikyu, Hirohide Ishige, Michael Albers, Yasuhisa Endo Mechanism of the Tissue-Specific Action of the Selective Androgen Receptor Modulator S-101479 Biol Pharm Bull 2013 36(3):442-51 PubMed ID: 23449329 DOI: 10.1248/bpb.b12-00885

9357 Yohei Hanazaki, Jyun-ichi Masumoto, Shoichi Sato, Kazuya Furusawa, Akimasa Fukui, Naoki Sasaki Multiscale Analysis of Changes in an Anisotropic Collagen Gel Structure by Culturing Osteoblasts ACS Appl Mater Interfaces 2013 5(13):5937-46 PubMed ID: 23806015 DOI: 10.1021/am303254e

9359 Yuriko Furuya, Atsushi Inagaki, Masud Khan, Kaoru Mori, Josef M Penninger, Midori Nakamura, Nobuyuki Udagawa, Kazuhiro Aoki, Keiichi Ohya, Kohji Uchida, Hisataka Yasuda Stimulation of Bone Formation in Cortical Bone of Mice Treated With a Receptor Activator of Nuclear factor-κB Ligand (RANKL)-binding Peptide That Possesses Osteoclastogenesis Inhibitory Activity J Biol Chem 2013 288(8):5562-71 PubMed ID: 23319583 DOI: 10.1074/jbc.M112.426080

9360 Tetsuo Asakura, Yu Suzuki, Aya Nagano, David Knight, Masakatsu Kamiya, Makoto Demura Synthesis and Characterization of Water-Soluble Silk Peptides and Recombinant Silk Protein Containing Polyalanine, the Integrin Binding Site, and Two Glutamic Acids at Each Terminal Site as a Possible Candidate for Use in Bone Repair Materials Biomacromolecules 2013 14(10):3731-41 PubMed ID: 24004453 DOI: 10.1021/bm401118m

9361 Joaquín Ródenas-Rochina 1, José Luis Gómez Ribelles, Myriam Lebourg Comparative Study of PCL-HAp and PCL-bioglass Composite Scaffolds for Bone Tissue Engineering J Mater Sci Mater Med 2013 24(5):1293-308 PubMed ID: 23417519 DOI: 10.1007/s10856-013-4878-5

9362 Soner Çakmak, Anıl Sera Çakmak, Menemşe Gümüşderelioğlu RGD-bearing Peptide-Amphiphile-Hydroxyapatite Nanocomposite Bone Scaffold: An in Vitro Study Biomed Mater 2013 8(4):045014 PubMed ID: 23860136 DOI: 10.1088/1748-6041/8/4/045014

9364 Michiyo Tsuru, Takashi Soejima, Naoto Shiba, Kimiko Kimura, Kimiaki Sato, Yoshiaki Toyama, Kensei Nagata Proline/arginine-rich End Leucine-Rich Repeat Protein Converts Stem Cells to Ligament Tissue and Zn(II) Influences Its Nuclear Expression Stem Cells Dev 2013 22(14):2057-70 PubMed ID: 23442027 DOI: 10.1089/scd.2012.0695

9285 Gibson S.Nyanhong, Rosario Díaz Rodríguez, Endry Nugroho Prasetyo, Cristina Caparrós, Clarisse Ribeiro, Vitor Sencadasd, Senentxu Lanceros-Mendez, Enrique Herrero Acerobe Georg M.Guebitz Bioactive albumin functionalized polylactic acid membranes for improved biocompatibility Reactive and Functional Polymers 2013 73:1399-1404 DOI: 10.1016/j.reactfunctpolym.2012.12.007

9286 Yosuke Shinozaki, Tsukasa Yanagi, Yuichiro Yamaguchi, Hirofumi Kido, Tadao Fukushima Osteogenic Evaluation of DNA/Protamine Complex Paste in Rat Cranial Defects Journal of Hard Tissue Biology 2013 22:401-408 DOI: 10.2485/jhtb.22.401

9287 Chunxia Gao, Mohamed N Rahaman, Qiang Gao, Akira Teramoto, Koji Abe Robotic Deposition and in Vitro Characterization of 3D Gelatin-Bioactive Glass Hybrid Scaffolds for Biomedical Applications J Biomed Mater Res A 2013 101(7):2027-37 PubMed ID: 23255226 DOI: 10.1002/jbm.a.34496

9288 Kimberly Sloan Stakleff, Fei Lin, Laura A Smith Callahan, Mary Beth Wade, Andrew Esterle, James Miller, Matthew Graham, Matthew L Becker Resorbable, Amino Acid-Based Poly(ester Urea)s Crosslinked With Osteogenic Growth Peptide With Enhanced Mechanical Properties and Bioactivity Acta Biomater 2013 9(2):5132-42 PubMed ID: 22975625 DOI: 10.1016/j.actbio.2012.08.035

15473 Noboru Hasegawa, Lin Mei, Miyako Mochizuki Pycnogenol® enhances proliferation and mineralization in osteoblast-like MC3T3-E1 cells Phytopharmacology 2013 4:569-574

15474 Toshihiko Shiraishi, Takuya Ohara, Shin Morishita A Method for Applying High Cyclic Strain to Focal Adhesions and Measuring the Cell Response Biomedical and Biotechnology Engineering 2013 3B DOI: 10.1115/imece2013-64681

17408 Ramalingam M, Young MF, Thomas V, Sun L, Chow LC, Tison CK, Chatterjee K, Miles WC, Simon CG Jr. Nanofiber scaffold gradients for interfacial tissue engineering J Biomater Appl 2013 27(6):695-705 PubMed ID: 22286209 DOI: 10.1177/0885328211423783

7585 Aira Matsugaki, Gento Aramoto, Takayoshi Nakano The alignment of MC3T3-E1 osteoblasts on steps of slip traces introduced by dislocation motion Biomaterials 2012 33・30:7327－7335 PubMed ID: 22818653 DOI: 10.1016/j.biomaterials.2012.06.022

7624 Wei K, Li Y, Mugishima H, Teramoto A, Abe K. Fabrication of core-sheath structured fibers for model drug release and tissue engineering by emulsion electrospinning. Biotechnol J 2012 7:677-85 PubMed ID: 22125296 DOI: 10.1002/biot.201000473

7640 Kim DY, Park YG, Quan HY, Kim SJ, Jung MS, Chung SH. Ginsenoside Rd stimulates the differentiation and mineralization of osteoblastic MC3T3-E1 cells by activating AMP-activated protein kinase via the BMP-2 signaling pathway. Fitoterapia 2012 83:215-22 PubMed ID: 22061660 DOI: 10.1016/j.fitote.2011.10.017

7693 Choi BH, Choi YS, Hwang DS, Cha HJ. Facile surface functionalization with glycosaminoglycans by direct coating with mussel adhesive protein. Tissue Eng Part C Methods 2012 18:71-9 PubMed ID: 21895565 DOI: 10.1089/ten.TEC.2011.0384

19072 Hwang Do Cha, Jung Min Hong, Tae-Yun Kang, Jin Woo Jung, Dong-Heon Ha, Dong-Woo Cho Effects of micro-patterns in three-dimensional scaffolds for tissue engineering applications Journal of Micromechanics and Microengineering 2012 22:125002 DOI: 10.1088/0960-1317/22/12/125002

5431 Shigeo M. TANAKA Intracellular Ca2+ Responses of 3D-Cultured Osteoblasts to Dynamic Loading Journal of Biomechanical Science and Engineering 2012 7:318-327 DOI: 10.1299/jbse.7.318

6171 Cetin D, Kahraman AS, Gümüşderelioğlu M. Novel pHEMA-gelatin SPHs as bone scaffolds in dynamic cultures. J Mater Sci Mater Med 2012 23(11):2803-12 PubMed ID: 22872315 DOI: 10.1007/s10856-012-4726-z

4395 Hasebe A, Nakamura Y, Tashima H, Takahashi K, Iijima M, Yoshimoto N, Ting K, Kuroda S, Niimi T. The C-terminal region of NELL1 mediates osteoblastic cell adhesion through integrin α3β1. FEBS Lett 2012 586(16):2500-6 PubMed ID: 22728432 DOI: 10.1016/j.febslet.2012.06.014

6552 Takarada T, Takarada-Iemata M, Takahata Y, Yamada D, Yamamoto T, Nakamura Y, Hinoi E, Yoneda Y. Osteoclastogenesis is negatively regulated by D-serine produced by osteoblasts. J Cell Physiol 2012 227(10):3477-87 PubMed ID: 22252936 DOI: 10.1002/jcp.24048

5831 Masayuki Tsukasaki , Atsushi Yamada, Kentaro Yoshimura, Agasa Miyazono, Matsuo Yamamoto, Masamichi Takami, Yoichi Miyamoto, Naoko Morimura, Ryutaro Kamijo Nephronectin Expression Is Regulated by SMAD Signaling in Osteoblast-Like MC3T3-E1 Cells Biochem Biophys Res Commun 2012 425(2):390-2 PubMed ID: 22842459 DOI: 10.1016/j.bbrc.2012.07.106

9196 Tohru Hayakawa, Eiji Yoshida, Yoshitaka Yoshimura, Motohiro Uo, Masao Yoshinari MC3T3-E1 Cells on Titanium Surfaces With Nanometer Smoothness and Fibronectin Immobilization Int J Biomater 2012 2012:743465 PubMed ID: 22675359 DOI: 10.1155/2012/743465

9198 Eun Jung Kwak 1, Young Soon Lee, Eun Mi Choi Effect of Magnolol on the Function of Osteoblastic MC3T3-E1 Cells Mediators Inflamm 2012 2012:829650 PubMed ID: 22474400 DOI: 10.1155/2012/829650

9199 Eiji Yoshida, Yoshitaka Yoshimura, Motohiro Uo, Masao Yoshinari, Tohru Hayakawa Influence of Nanometer Smoothness and Fibronectin Immobilization of Titanium Surface on MC3T3-E1 Cell Behavior J Biomed Mater Res A 2012 100(6):1556-64 PubMed ID: 22447768 DOI: 10.1002/jbm.a.34084

9200 Yoshikazu Mikami, Shinnosuke Suzuki, Yumiko Ishii, Nobukazu Watanabe, Tomihisa Takahashi, Keitaro Isokawa, Masaki J Honda The p75 Neurotrophin Receptor Regulates MC3T3-E1 Osteoblastic Differentiation Differentiation 2012 84(5):392-9 PubMed ID: 22906707 DOI: 10.1016/j.diff.2012.07.001

9201 Chieko Shionome, Takayuki Kawato, Natsuko Tanabe, Taro Kariya, Rina Sanuki, Yuki Koyama, Naoto Suzuki, Noriyoshi Shimizu, Masao Maeno Compressive Force Induces the Expression of Bone Remodeling-Related Proteins via Interleukin-11 Production in MC3T3-E1 Cells Journal of Hard Tissue Biology 2012 21:65-74 DOI: 10.2485/jhtb.21.65

9202 Tomohiro Itoh, Masashi Ando, Yasuyuki Tsukamasa, Yukihiro Akao Expression of BMP-2 and Ets1 in BMP-2-stimulated Mouse Pre-Osteoblast Differentiation Is Regulated by microRNA-370 FEBS Lett 2012 586(12):1693-701 PubMed ID: 22587915 DOI: 10.1016/j.febslet.2012.04.014

9203 CHUNRONG YANG Enhanced physicochemical properties of collagen by using EDC/NHS-crosslinking Bulletin of Materials Science 2012 35:913–918 DOI: 10.1007/s12034-012-0376-5

9204 Takayuki Nonoyama, Takatoshi Kinoshita, Masahiro Higuchi, Kenji Nagata, Masayoshi Tanaka, Mari Kamada, Kimiyasu Sato, Katsuya Kato Arrangement techniques of proteins and cells using amorphous calcium phosphate nanofiber scaffolds Applied Surface Science 2012 262:8-12 DOI: 10.1016/j.apsusc.2011.12.009

9206 A.Valanezhad, K.Tsuru, M.Maruta, G.Kawachi, S.Matsuya, K.Ishikawa A new biocompatible coating layer applied on titanium substrates using a modified zinc phosphatizing method Surface and Coatings Technology 2012 206:2207-2212 DOI: 10.1016/j.surfcoat.2011.09.064

9207 C. Ribeiro a, S. Moreira b, V. Correia ac, V. Sencadas ad, J.G. Rocha c, F. M. Gama b, J. L. Gómez Ribelles ef and S. Lanceros-Méndez Enhanced proliferation of pre-osteoblastic cells by dynamic piezoelectric stimulation 2012 2:11504-11509 DOI: 10.1039/C2RA21841K

9208 Kenichi Harimoto, Yasuhiro Yoshida, Kumiko Yoshihara, Noriyuki Nagaoka, Takuya Matsumoto, Yoh-ichi Tagawa Osteoblast Compatibility of Materials Depends on Serum Protein Absorbability in Osteogenesis Dent Mater J 2012 31(4):674-80 PubMed ID: 22864224 DOI: 10.4012/dmj.2012-075

9209 ChunRong Yang, YingJun Wang, XiaoFeng Chen Mineralization Regulation and Biological Influence of Bioactive Glass-Collagen-Phosphatidylserine Composite Scaffolds Sci China Life Sci 2012 55(3):236-40 PubMed ID: 22527520 DOI: 10.1007/s11427-012-4291-1

9210 Masayuki Shimizu, Yasuhiro Kobayashi, Toshihide Mizoguchi, Hiroaki Nakamura, Ichiro Kawahara, Nobuyo Narita, Yuki Usui, Kaoru Aoki, Kazuo Hara, Hisao Haniu, Nobuhide Ogihara, Norio Ishigaki, Koichi Nakamura, Hiroyuki Kato, Masatomo Kawakubo, Yoshiko Dohi, Seiichi Taruta, Yoong Ahm Kim, Morinobu Endo, Hidehiro Ozawa, Nobuyuki Udagawa, Naoyuki Takahashi, Naoto Saito Carbon Nanotubes Induce Bone Calcification by Bidirectional Interaction With Osteoblasts Adv Mater 2012 24(16):2176-85 PubMed ID: 22447724 DOI: 10.1002/adma.201103832

9211 Hiroaki Watanabe, Kensuke Saito, Katsutoshi Kokubun, Hodaka Sasaki, Masao Yoshinari Change in Surface Properties of Zirconia and Initial Attachment of Osteoblastlike Cells With Hydrophilic Treatment Dent Mater J 2012 31(5):806-14 PubMed ID: 23037844 DOI: 10.4012/dmj.2012-069

9212 V. Sencadas, C. Ribeiro, J. Nunes-Pereira, V. Correia & S. Lanceros-Méndez Fiber average size and distribution dependence on the electrospinning parameters of poly(vinylidene fluoride–trifluoroethylene) membranes for biomedical applications Applied Physics A 2012 109:685–691 DOI: 10.1007/s00339-012-7101-5

9213 Kaushik Chatterjee, Stevephen Hung 2, Girish Kumar 3, Carl G Simon 4 Time-Dependent Effects of Pre-Aging 3D Polymer Scaffolds in Cell Culture Medium on Cell Proliferation J Funct Biomater 2012 3(2):372-81 PubMed ID: 24955538 DOI: 10.3390/jfb3020372

9214 Ming-Yue Huang, Ujjial K Bhawal, Noboru Kuboyama, Wei-Jen Chang, Sheng-Yang Lee, Yoshimitsu Abiko Effect of Reactive Oxygen on Hyaluronan Mediated Motility Receptor Expression in Osteoblasts Journal of Hard Tissue Biology 2012 21:127-132 DOI: 10.2485/jhtb.21.127

9215 Tomohiro Itoh, Yuko Ito, Yoshinori Ohtsuki, Masashi Ando, Yasuyuki Tsukamasa, Nami Yamada, Tomoki Naoe, Yukihiro Akao Microvesicles Released From Hormone-Refractory Prostate Cancer Cells Facilitate Mouse Pre-Osteoblast Differentiation J Mol Histol 2012 43(5):509-15 PubMed ID: 22526510 DOI: 10.1007/s10735-012-9415-1

9216 Hong Li, Yunsheng Ge, Pengyun Zhang, Lingxiang Wu, Shiyi Chen The Effect of Layer-By-Layer Chitosan-Hyaluronic Acid Coating on Graft-To-Bone Healing of a Poly(ethylene Terephthalate) Artificial Ligament J Biomater Sci Polym Ed 2012 23(1-4):425-38 PubMed ID: 21255485 DOI: 10.1163/092050610X551989

9217 Hiromi Ochiai, Shoko Okada, Akiko Saito, Kazuto Hoshi, Haruto Yamashita, Tsuyoshi Takato, Toshifumi Azuma Inhibition of Insulin-Like Growth factor-1 (IGF-1) Expression by Prolonged Transforming Growth factor-β1 (TGF-β1) Administration Suppresses Osteoblast Differentiation J Biol Chem 2012 287(27):22654-61 PubMed ID: 22573330 DOI: 10.1074/jbc.M111.279091

9219 Aira Matsugaki, Gento Aramoto, Takuya Ishimoto, Takayoshi Nakano Control of Osteoblastic Cell Behavior by Surface Topography Introduced by Plastic Deformation of Ti Single Crystal with h.c.p. Structure Materials Science Forum 2012 706-709 DOI: 10.4028/www.scientific.net/MSF.706-709.549

9220 ChunRong Yang, YingJun Wang & XiaoFeng Chen Preparation and evaluation of biomimetric nano-hydroxyapatite-based composite scaffolds for bone-tissue engineering Chinese Science Bulletin 2012 57:2787–2792 DOI: 10.1007/s11434-012-5201-4

9221 Jung-Seob Lee, Hwang Do Cha, Jin-Hyung Shim, Jin Woo Jung, Jong Young Kim, Dong-Woo Cho Effect of Pore Architecture and Stacking Direction on Mechanical Properties of Solid Freeform Fabrication-Based Scaffold for Bone Tissue Engineering J Biomed Mater Res A 2012 100(7):1846-53 PubMed ID: 22488723 DOI: 10.1002/jbm.a.34149

9222 Rikako Miyamoto, Asuka Ozawa, Takeshi Yamada, Hirobumi Shibata, Katsumi Yoshida, Osamu Yamanuro, Kazuaki Hashimoto PROLIFERATION AND DIFFERENTIATION OF OSTEOBLAST-LIKE CELLS ON β-TRICALCIUM PHOSPHATE DOPED WITH MANGANESE (II) IONS Phosphorus Research Bulletin 2012 26:87-90 DOI: 10.3363/prb.26.87

9223 Inho Han, Barbora Vagaska, Hyok Jin Seo, Jae Kyeong Kang, Byeong-Ju Kwon, Mi Hee Lee, Jong-Chul Parkb Promoted cell and material interaction on atmospheric pressure plasma treated titanium Applied Surface Science 2012 258:4718-4723 DOI: 10.1016/j.apsusc.2012.01.065

9224 Menemşe Gümüşderelioğlu, Anıl S. Kahraman & Ali Tuncel Magnetic poly(glycerol dimethacrylate) latex particles: synthesis, characterization and cellular interactions Polymer Bulletin 2012 69:323–335 DOI: 10.1007/s00289-012-0732-z

9225 Fukunaga Otsuka, Yu Kataoka, Takashi Miyazaki Enhanced Osteoblast Response to Electrical Discharge Machining Surface Dent Mater J 2012 31(2):309-15 PubMed ID: 22447066 DOI: 10.4012/dmj.2011-039

9226 Tadashi Honjo, Satoshi Kubota, Hiroshi Kamioka, Yasuyo Sugawara, Yoshihito Ishihara, Takashi Yamashiro, Masaharu Takigawa, Teruko Takano-Yamamoto Promotion of Ccn2 Expression and Osteoblastic Differentiation by Actin Polymerization, Which Is Induced by Laminar Fluid Flow Stress J Cell Commun Signal 2012 6(4):225-32 PubMed ID: 22956334 DOI: 10.1007/s12079-012-0177-z

9228 Jong Bum KIM, Toshimitsu OKUDERA, Toshitake FURUSAWA, Masaaki SATO, Weiqi YAN, Yuta MATSUSHIMA, Hidero UNUMA, Takashi SASANO In vivo and in vitro biological efficacy of double-layer coating of titanium with gelatin and calcium phosphate Journal of the Ceramic Society of Japan 2012 20:589-593 DOI: 10.2109/jcersj2.120.589

9229 Marco Cantini, Patricia Rico, David Moratal and Manuel Salmerón-Sánchez Controlled wettability, same chemistry: biological activity of plasma-polymerized coatings oft Matter 2012 8,:5575-5584 DOI: 10.1039/C2SM25413A

9230 Tingting Zhu, Bum-Soon Lim, Hee Chul Park, Kyung Mi Son, Hyeong-Cheol Yang Effects of the Iron-Chelating Agent Deferoxamine on Triethylene Glycol Dimethacrylate, 2-hydroxylethyl Methacrylate, Hydrogen Peroxide-Induced Cytotoxicity J Biomed Mater Res B Appl Biomater 2012 100(1):197-205 PubMed ID: 22102427 DOI: 10.1002/jbm.b.31939

9231 Kazuaki Nagayama, Yuki Kimura, Narutaka Makino, Takeo Matsumoto Strain Waveform Dependence of Stress Fiber Reorientation in Cyclically Stretched Osteoblastic Cells: Effects of Viscoelastic Compression of Stress Fibers Am J Physiol Cell Physiol 2012 302(10):C1469-78 PubMed ID: 22357736 DOI: 10.1152/ajpcell.00155.2011

9233 Takashi Watanabe, Yoshihiro Tamamura, Akiyoshi Hoshino, Yuji Makino, Hiroshi Kamioka, Teruo Amagasa, Akira Yamaguchi, Tadahiro Iimura Increasing Participation of Sclerostin in Postnatal Bone Development, Revealed by Three-Dimensional Immunofluorescence Morphometry Bone 2012 ;51(3):447-58 PubMed ID: 22766096 DOI: 10.1016/j.bone.2012.06.019

9234 Tomoyuki Koyama, Chie Nakajima, Sogo Nishimoto, Masamichi Takami, Je-Tae Woo, Kazunaga Yazawa Suppressive Effects of the Leaf of Terminalia Catappa L. On Osteoclast Differentiation in Vitro and Bone Weight Loss in Vivo J Nutr Sci Vitaminol (Tokyo) 2012 58(2):129-35 PubMed ID: 22790571 DOI: 10.3177/jnsv.58.129

9235 C Ribeiro, J A Panadero, V Sencadas, S Lanceros-Méndez, M N Tamaño, D Moratal, M Salmerón-Sánchez, J L Gómez Ribelles Fibronectin Adsorption and Cell Response on Electroactive Poly(vinylidene Fluoride) Films iomed Mater 2012 7(3):035004 PubMed ID: 22356773 DOI: 10.1088/1748-6041/7/3/035004

9236 Yang Wu, Shiyi Chen, Jia Jiang, Hong Li, K,ai Gao, Pengyun Zhang The Effect of 58S Bioactive Glass Coating on Polyethylene Terephthalates in Graft-Bone Healing Journal of Bionic Engineering 2012 9:470-477 DOI: 10.1016/S1672-6529(11)60133-9

9237 Kenichi Yamamoto, Hironori Hojo, Isao Koshima, Ung-il Chung, Shinsuke Ohba Famotidine Suppresses Osteogenic Differentiation of Tendon Cells in Vitro and Pathological Calcification of Tendon in Vivo J Orthop Res 2012 30(12):1958-62 PubMed ID: 22592911 DOI: 10.1002/jor.22146

9218 Norio Yamakawa, Kazuko Kaneda, Yusuke Saito, Emi Ichihara, Kazuhiro Morishita The Increased Expression of Integrin α6 (ITGA6) Enhances Drug Resistance in EVI1(high) Leukemia PLoS One 2012 7(1):e30706 PubMed ID: 22295105 DOI: 10.1371/journal.pone.0030706

9240 Hirotaka OOMINE, Megumi FUSE, Tohru HAYAKAWA, Masahiko FUKUMOTO Fabrication of the Fibronectin-immobilized Three-Dimensional Porous Poly(lactic acid) Scaffold and Initial Mouse Osteoblast-like Cell Attachment Journal of Oral Tissue Engineering 2012 10:59-66 DOI: 10.11223/jarde.10.59

9241 Chunxia Gao, Qiang Gao, Yadong Li, Mohamed N Rahaman, Akira Teramoto, Koji Abe Preparation and in Vitro Characterization of Electrospun PVA Scaffolds Coated With Bioactive Glass for Bone Regeneration J Biomed Mater Res A 2012 100(5):1324-34 PubMed ID: 22374712 DOI: 10.1002/jbm.a.34072

9242 Masahide Takedachi, Hiroyuki Oohara, Brenda J Smith, Mitsuyoshi Iyama, Mariko Kobashi, Kenichiro Maeda, Courtney L Long, Mary B Humphrey, Barbara J Stoecker, Satoru Toyosawa, Linda F Thompson, Shinya Murakami CD73-generated Adenosine Promotes Osteoblast Differentiation J Cell Physiol 2012 227(6):2622-31 PubMed ID: 21882189 DOI: 10.1002/jcp.23001

9243 Sang-Hyun An, Takuya Matsumoto, Hiroyuki Miyajima, Atsushi Nakahira, Kyo-Han Kim, Satoshi Imazato Porous Zirconia/Hydroxyapatite Scaffolds for Bone Reconstruction Dent Mater 2012 28(12):1221-31 PubMed ID: 23018082 DOI: 10.1016/j.dental.2012.09.001

9244 Murat Simşek, Merve Capkın, Ayşe Karakeçili, Menemşe Gümüşderelioğlu Chitosan and Polycaprolactone Membranes Patterned via Electrospinning: Effect of Underlying Chemistry and Pattern Characteristics on Epithelial/Fibroblastic Cell Behavior J Biomed Mater Res A 2012 100(12):3332-43 PubMed ID: 22733685 DOI: 10.1002/jbm.a.34287

9247 Yoshiyuki Wada, Morimichi Mizuno, Yoshinobu Nodasaka, Masato Tamura The Effect of Enamel Matrix Derivative on Spreading, Proliferation, and Differentiation of Osteoblasts Cultured on Zirconia Int J Oral Maxillofac Implants 2012 27(4):849-58 PubMed ID: 22848887

15472 Toshihiko Shiraishi, Takuya Ohara, Shin Morishita, Ryohei Takeuchi Response of an Osteoblast to Cyclic Strain at Its Focal Adhesions Using Magnetic Micropillars Biomedical and Biotechnology 2012 2 DOI: 10.1115/imece2012-89919

14283 Castillo JA, Borchmann DE, Cheng AY, Wang Y, Hu C, García AJ, Weck M. Well-defined Poly(lactic acid)s Containing Poly(ethylene glycol) Side-chains Macromolecules 2012 45(1):62-69 PubMed ID: 22279245 DOI: 10.1021/ma2016387

7586 Inaguma T, Han J, Isoda H. Improvement of insulin resistance by Cyanidin 3-glucoside, anthocyanin from black beans through the up-regulation of GLUT4 gene expression. BMC Proc 2011 5 Suppl 8:P21 PubMed ID: 22373152 DOI: 10.1186/1753-6561-5-S8-P21

7630 Skrtic D, Antonucci JM. Bioactive polymeric composites for tooth mineral regeneration: physicochemical and cellular aspects. J Funct Biomater 2011 2:271-307 PubMed ID: 22102967 DOI: 10.3390/jfb2030271

7634 Han SH, Kim KH, Han JS, Koo KT, Kim TI, Seol YJ, Lee YM, Ku Y, Rhyu IC. Response of osteoblast-like cells cultured on zirconia to bone morphogenetic protein-2. J Periodontal Implant Sci 2011 41:227-33 PubMed ID: 22087413 DOI: 10.5051/jpis.2011.41.5.227

7679 Takeuchi N, Machigashira M, Yamashita D, Shirakata Y, Kasuga T, Noguchi K, Ban S. Cellular compatibility of a gamma-irradiated modified siloxane-poly(lactic acid)-calcium carbonate hybrid membrane for guided bone regeneration. Dent Mater J 2011 30:730-8 PubMed ID: 21946495 DOI: 10.4012/dmj.2011-075

7694 Kriebitzsch C, Verlinden L, Eelen G, van Schoor NM, Swart K, Lips P, Meyer MB, Pike JW, Boonen S, Carlberg C, Vitvitsky V, Bouillon R, Banerjee R, Verstuyf A. 1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase. J. Bone Miner. Res. 2011 26:2991-3000 PubMed ID: 21898591 DOI: 10.1002/jbmr.493

7719 Takahata Y, Takarada T, Hinoi E, Nakamura Y, Fujita H, Yoneda Y. Osteoblastic γ-aminobutyric acid, type B receptors negatively regulate osteoblastogenesis toward disturbance of osteoclastogenesis mediated by receptor activator of nuclear factor κB ligand in mouse bone. J. Biol. Chem. 2011 286:32906-17 PubMed ID: 21828041 DOI: 10.1074/jbc.M111.253526

7736 Sawajiri M, Nomura Y, Banik S, Nishikiori R, Sonoda Y, Tanimoto K. Irradiation effect on osteoclastogenesis stimulated by breast cancer cells. Health Phys 2011 101:259-64 PubMed ID: 21799342 DOI: 10.1097/HP.0b013e3182118333

7744 Yoshida K, Higuchi C, Nakura A, Yoshikawa H. Spleen tyrosine kinase suppresses osteoblastic differentiation through MAPK and PKCα. Biochem. Biophys. Res. Commun. 2011 411:774-9 PubMed ID: 21782794 DOI: 10.1016/j.bbrc.2011.07.023

7758 Ren G, Wang K, Chang R, Su Y, Wang J, Su J, Han B. Simultaneous administration of fluoride and selenite regulates proliferation and apoptosis in murine osteoblast-like MC3T3-E1 cells by altering osteoprotegerin. Biol Trace Elem Res 2011 144:1437-48 PubMed ID: 21739163 DOI: 10.1007/s12011-011-9130-x

7773 Tsukasaki M, Yamada A, Suzuki D, Aizawa R, Miyazono A, Miyamoto Y, Suzawa T, Takami M, Yoshimura K, Morimura N, Yamamoto M, Kamijo R. Expression of POEM, a positive regulator of osteoblast differentiation, is suppressed by TNF-α. Biochem. Biophys. Res. Commun. 2011 410:766-70 PubMed ID: 21689636 DOI: 10.1016/j.bbrc.2011.06.048

7774 Furugaki K, Moriya Y, Iwai T, Yorozu K, Yanagisawa M, Kondoh K, Fujimoto-Ohuchi K, Mori K. Erlotinib inhibits osteolytic bone invasion of human non-small-cell lung cancer cell line NCI-H292. Clin. Exp. Metastasis 2011 28:649-59 PubMed ID: 21688034 DOI: 10.1007/s10585-011-9398-4

7777 Okamura H, Yoshida K, Ochiai K, Haneji T. Reduction of protein phosphatase 2A Cα enhances bone formation and osteoblast differentiation through the expression of bone-specific transcription factor Osterix. Bone 2011 49:368-75 PubMed ID: 21683816 DOI: 10.1016/j.bone.2011.06.004

7790 Kataoka Y, Tamaki Y, Miyazaki T. Synergistic responses of superficial chemistry and micro topography of titanium created by wire-type electric discharge machining. Biomed Mater Eng 2011 21:113-21 PubMed ID: 21654067 DOI: 10.3233/BME-2011-0661

7792 Zhang W, Wang H, Oyane A, Tsurushima H, Chu PK. Osteoblast differentiation and disinfection induced by nitrogen plasma-treated surfaces. Biomed Mater Eng 2011 21:75-82 PubMed ID: 21654064 DOI: 10.3233/BME-2011-0657

7802 Tagaya M, Ikoma T, Takemura T, Hanagata N, Yoshioka T, Tanaka J. Effect of interfacial proteins on osteoblast-like cell adhesion to hydroxyapatite nanocrystals. Langmuir 2011 27:7645-53 PubMed ID: 21615097 DOI: 10.1021/la200621p

7812 Tagaya M, Ikoma T, Takemura T, Hanagata N, Okuda M, Yoshioka T, Tanaka J. Detection of interfacial phenomena with osteoblast-like cell adhesion on hydroxyapatite and oxidized polystyrene by the quartz crystal microbalance with dissipation. Langmuir 2011 27:7635-44 PubMed ID: 21595447 DOI: 10.1021/la200008z

7819 Yonezawa T, Lee JW, Hibino A, Asai M, Hojo H, Cha BY, Teruya T, Nagai K, Chung UI, Yagasaki K, Woo JT. Harmine promotes osteoblast differentiation through bone morphogenetic protein signaling. Biochem. Biophys. Res. Commun. 2011 409:260-5 PubMed ID: 21570953 DOI: 10.1016/j.bbrc.2011.05.001

7827 Yonezawa T, Lee JW, Akazawa H, Inagaki M, Cha BY, Nagai K, Yagasaki K, Akihisa T, Woo JT. Osteogenic activity of diphenyl ether-type cyclic diarylheptanoids derived from Acer nikoense. Bioorg. Med. Chem. Lett. 2011 21:3248-51 PubMed ID: 21550801 DOI: 10.1016/j.bmcl.2011.04.041

7829 Shoji K, Tsubaki M, Yamazoe Y, Satou T, Itoh T, Kidera Y, Tanimori Y, Yanae M, Matsuda H, Taga A, Nakamura H, Nishida S. Mangiferin induces apoptosis by suppressing Bcl-xL and XIAP expressions and nuclear entry of NF-κB in HL-60 cells. Arch. Pharm. Res. 2011 34:469-75 PubMed ID: 21547680 DOI: 10.1007/s12272-011-0316-8

7834 Hagiwara K, Goto T, Araki M, Miyazaki H, Hagiwara H. Olive polyphenol hydroxytyrosol prevents bone loss. Eur. J. Pharmacol. 2011 662:78-84 PubMed ID: 21539839 DOI: 10.1016/j.ejphar.2011.04.023

7837 Kang KS, Lee SJ, Lee HS, Moon W, Cho DW. Effects of combined mechanical stimulation on the proliferation and differentiation of pre-osteoblasts. Exp. Mol. Med. 2011 43:367-73 PubMed ID: 21532314 DOI: 10.3858/emm.2011.43.6.040

7855 Shimizu T, Tanaka T, Iso T, Matsui H, Ooyama Y, Kawai-Kowase K, Arai M, Kurabayashi M. Notch signaling pathway enhances bone morphogenetic protein 2 (BMP2) responsiveness of Msx2 gene to induce osteogenic differentiation and mineralization of vascular smooth muscle cells. J. Biol. Chem. 2011 286:19138-48 PubMed ID: 21471203 DOI: 10.1074/jbc.M110.175786

7870 Wei K, Li Y, Kim KO, Nakagawa Y, Kim BS, Abe K, Chen GQ, Kim IS. Fabrication of nano-hydroxyapatite on electrospun silk fibroin nanofiber and their effects in osteoblastic behavior. J Biomed Mater Res A 2011 97:272-80 PubMed ID: 21442728 DOI: 10.1002/jbm.a.33054

7885 Ma C, Zhang J, Fu J, Cheng L, Zhao G, Gu Y. Up-regulation of VEGF by MC3T3-E1 cells treated with curculigoside. Phytother Res 2011 25:922-6 PubMed ID: 21394809 DOI: 10.1002/ptr.3449

7895 Fukuno N, Matsui H, Kanda Y, Suzuki O, Matsumoto K, Sasaki K, Kobayashi T, Tamura S. TGF-β-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts. Biochem. Biophys. Res. Commun. 2011 408:202-7 PubMed ID: 21371434 DOI: 10.1016/j.bbrc.2011.02.127

7911 Tamaki Y, Lee WS, Kataoka Y, Miyazaki T. A modified porous titanium sheet prepared by plasma-activated sintering for biomedical applications. J Tissue Eng 2011 2010:425402 PubMed ID: 21350650 DOI: 10.4061/2010/425402

7916 Ogata N, Shinoda Y, Wettschureck N, Offermanns S, Takeda S, Nakamura K, Segre GV, Chung UI, Kawaguchi H. G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone. J. Biol. Chem. 2011 286:13733-40 PubMed ID: 21345793 DOI: 10.1074/jbc.M110.200196

7926 Okada E, Yamanaka M, Ishikawa O. New insights into the mechanism of abnormal calcification in nephrogenic systemic fibrosis - gadolinium promotes calcium deposition of mesenchymal stem cells and dermal fibroblasts. J. Dermatol. Sci. 2011 62:58-63 PubMed ID: 21334857 DOI: 10.1016/j.jdermsci.2011.01.009

7947 Uno K, Takarada T, Nakamura Y, Fujita H, Hinoi E, Yoneda Y. A negative correlation between expression profiles of runt-related transcription factor-2 and cystine/glutamate antiporter xCT subunit in ovariectomized mouse bone. J. Pharmacol. Sci. 2011 115:309-19 PubMed ID: 21325781 DOI: 10.1254/jphs.10310fp

7950 Miura K, Yamada N, Hanada S, Jung TK, Itoi E. The bone tissue compatibility of a new Ti-Nb-Sn alloy with a low Young's modulus. Acta Biomater 2011 7:2320-6 PubMed ID: 21316491 DOI: 10.1016/j.actbio.2011.02.008

7952 Kihara T, Ichikawa S, Yonezawa T, Lee JW, Akihisa T, Woo JT, Michi Y, Amagasa T, Yamaguchi A. Acerogenin A, a natural compound isolated from Acer nikoense Maxim, stimulates osteoblast differentiation through bone morphogenetic protein action. Biochem. Biophys. Res. Commun. 2011 406:211-7 PubMed ID: 21303661 DOI: 10.1016/j.bbrc.2011.02.017

7954 Uno K, Takarada T, Takarada-Iemata M, Nakamura Y, Fujita H, Hinoi E, Yoneda Y. Negative regulation of osteoblastogenesis through downregulation of runt-related transcription factor-2 in osteoblastic MC3T3-E1 cells with stable overexpression of the cystine/glutamate antiporter xCT subunit. J. Cell. Physiol. 2011 226:2953-64 PubMed ID: 21302293 DOI: 10.1002/jcp.22642

7969 Mikami Y, Senoo M, Lee M, Yamada K, Ochiai K, Honda MJ, Watanabe E, Watanabe N, Somei M, Takagi M. Inhibitory effects of a tryptamine derivative on ultraviolet radiation-induced apoptosis in MC3T3-E1 mouse osteoblasts. J. Pharmacol. Sci. 2011 115:214-20 PubMed ID: 21282935 DOI: 10.1254/jphs.10208fp

7996 Kim BY, Yoon HY, Yun SI, Woo ER, Song NK, Kim HG, Jeong SY, Chung YS. In vitro and in vivo inhibition of glucocorticoid-induced osteoporosis by the hexane extract of Poncirus trifoliata. Phytother Res 2011 25:1000-10 PubMed ID: 21225901 DOI: 10.1002/ptr.3373

8017 Lin J, Fan YJ, Mehl C, Zhu JJ, Chen H, Jin LY, Xu JH, Wang HM. Eucommia ulmoides Oliv. antagonizes H2O2-induced rat osteoblastic MC3T3-E1 apoptosis by inhibiting expressions of caspases 3, 6, 7, and 9. J Zhejiang Univ Sci B 2011 12:47-54 PubMed ID: 21194186 DOI: 10.1631/jzus.B1000057

8029 Chatterjee K, Young MF, Simon CG Jr. Fabricating gradient hydrogel scaffolds for 3D cell culture. Comb. Chem. High Throughput Screen. 2011 14:227-36 PubMed ID: 21143178 DOI: 10.2174/138620711795222455

8054 Chatterjee K, Sun L, Chow LC, Young MF, Simon CG Jr. Combinatorial screening of osteoblast response to 3D calcium phosphate/poly(ε-caprolactone) scaffolds using gradients and arrays. Biomaterials 2011 32:1361-9 PubMed ID: 21074846 DOI: 10.1016/j.biomaterials.2010.10.043

8064 Lam WM, Pan HB, Fong MK, Cheung WS, Wong KL, Li ZY, Luk KD, Chan WK, Wong CT, Yang C, Lu WW. In Vitro characterization of low modulus linoleic acid coated strontium-substituted hydroxyapatite containing PMMA bone cement. J. Biomed. Mater. Res. Part B Appl. Biomater. 2011 96:76-83 PubMed ID: 21053263 DOI: 10.1002/jbm.b.31741

8098 Zhang F, Tanaka H, Kawato T, Kitami S, Nakai K, Motohashi M, Suzuki N, Wang CL, Ochiai K, Isokawa K, Maeno M. Interleukin-17A induces cathepsin K and MMP-9 expression in osteoclasts via celecoxib-blocked prostaglandin E2 in osteoblasts. Biochimie 2011 93:296-305 PubMed ID: 20937352 DOI: 10.1016/j.biochi.2010.10.001

8101 Lee JW, Kang KS, Lee SH, Kim JY, Lee BK, Cho DW. Bone regeneration using a microstereolithography-produced customized poly(propylene fumarate)/diethyl fumarate photopolymer 3D scaffold incorporating BMP-2 loaded PLGA microspheres. Biomaterials 2011 32:744-52 PubMed ID: 20933279 DOI: 10.1016/j.biomaterials.2010.09.035

8121 Hanagata N, Li X, Morita H, Takemura T, Li J, Minowa T. Characterization of the osteoblast-specific transmembrane protein IFITM5 and analysis of IFITM5-deficient mice. J. Bone Miner. Metab. 2011 29:279-90 PubMed ID: 20838829 DOI: 10.1007/s00774-010-0221-0

8203 Cetin D, Kahraman AS, Gumu?derelio?lu M. Novel scaffolds based on poly(2-hydroxyethyl methacrylate) superporous hydrogels for bone tissue engineering. J Biomater Sci Polym Ed 2011 22:1157-78 PubMed ID: 20615330 DOI: 10.1163/092050610X501704

8306 Nagata M, Lonnerdal B. Role of zinc in cellular zinc trafficking and mineralization in a murine osteoblast-like cell line. J. Nutr. Biochem. 2011 22:172-8 PubMed ID: 20378322 DOI: 10.1016/j.jnutbio.2010.01.003

18557 José Antonio Gómez-Tejedor, Niek Van Overberghe, Patricia Rico, José Luís Gómez Ribelles Assessment of the parameters influencing the fiber characteristics of electrospun poly(ethyl methacrylate) membranes European Polymer Journal 2011 47:119-129 DOI: 10.1016/j.eurpolymj.2010.10.034

19358 Ji-Hye Lee, Yu-Bin Lee, Nae-Gyune Rim, Sun-Young Jo, Youn-Mook Lim, Heungsoo Shin Development and characterization of nanofibrous poly(lactic-co-glycolic acid)/biphasic calcium phosphate composite scaffolds for enhanced osteogenic differentiation Macromolecular Research 2011 19:172-179 DOI: 10.1007/s13233-011-0206-4

5524 Yoshimi Tsuruma, Hiroe Maruyama, Yoko Araki Effect of a Glycoprotein (Apisin) in Royal Jelly on Proliferation and Differentiation in Skin Fibroblast and Osteoblastic Cells Nippon Shokuhin Kagaku Kogaku Kaishi 2011 58:121-126 DOI: 10.3136/nskkk.58.121

6307 Igarashi M, Sakamoto K, Nagaoka I. Effect of glucosamine, a therapeutic agent for osteoarthritis, on osteoblastic cell differentiation. Int J Mol Med 2011 28(3):373-9 PubMed ID: 21537831 DOI: 10.3892/ijmm.2011.686

7957 RETNO WIDYOWATI Alkaline phosphatase activity of Graptophyllum pictum and Sphilanthes acmella fractions against MC3T3-E1 cells as marker of osteoblast differentiation cells Int J Pharm Pharm Sci 2011 3:3437

7964 Masafumi Sakonoa, Shigenori Akiyama, Tamotsu Zakoa, Shujiro Sakaki, Tomonori Waku, Naoki Tanaka, Mizuo Maeda Application of two morphologically different fibrillar and filamentous insulin amyloids as a biomaterial for cell culture surfaces Reactive and Functional Polymers 2011 71:324-328 DOI: 10.1016/j.reactfunctpolym.2010.10.012

8018 Menemşe Gümüşderelioğlu, Ayşe Karakeçili, T Tolga Demirtaş Osteogenic activities of MC3T3-E1 cells on heparin-immobilized poly (caprolactone) membranes Journal of Bioactive and Compatible Polymers 2011 26:257-269 DOI: 10.1177/0883911511406329

8142 Hong Li, Yang Wu, Yunsheng Ge, Jia Jiang, Kai Gao, Pengyun Zhang, Lingxiang Wu, Shiy iChen Composite coating of 58S bioglass and hydroxyapatite on a poly (ethylene terepthalate) artificial ligament graft for the graft osseointegration in a bone tunnel Applied Surface Science 2011 257:9371-9376 DOI: 10.1016/j.apsusc.2011.05.110

8213 Antonucci JM, Davis CH, Sun J, O'Donnell JN, Skrtic D. Leachability and Cytotoxicity of an Experimental Polymeric ACP Composite. PMSE Preprints 2011 104:300-302 PubMed ID: 26457070

8254 Piyanuch Sommani, Hiroshi Tsuji, Hiroko Sato, Yasuhito Gotoh, Gikan H. Takaoka Osteoblast Patterning on Silicone Rubber by using Mesenchymal Stem Cells and Carbon Negative-Ion Implantation Transactions of the Materials Research Society of Japan 2011 36:317-320 DOI: 10.14723/tmrsj.36.317

8298 Chen X, Meng Y, Wang Y, Du C, Yang C. A Biomimetic Material with a High Bio-responsibility for Bone Reconstruction and Tissue Engineering. J Biomater Sci Polym Ed 2011 22(1-3):153-63 PubMed ID: 20546681 DOI: 10.1163/092050609X12583524936191

8299 Keita Ishiwata, Katsuaki Imamiya, Tetsuya Mizukami, Yoshimitsu Abiko Reduction of BIRC6 Gene expression by reactive oxygen stress in osteoblasts International Journal of Oral-Medical Sciences 2011 10:67-71 DOI: 10.5466/ijoms.10.67

8302 T.C. Gamboa-Martínez, J.L. Gómez Ribelles, G. Gallego Ferrer Fibrin coating on poly (L-lactide) scaffolds for tissue engineering 2011 26:464-477 DOI: 10.1177/0883911511419834

8313 Jung Hwal Shin, Jin Woo Lee, Jin Hwa Jung, Dong-Woo Cho & Geunbae Lim Evaluation of cell proliferation and differentiation on a poly(propylene fumarate) 3D scaffold treated with functional peptides Journal of Materials Science 2011 46:5282–5287 DOI: 10.1007/s10853-011-5467-y

8317 Kiyoto Takemoto, Kenichi Matsuzaka, Masaki Shimono, Masao Yoshinari, Takashi Inoue The effect of different surface roughnesses on the differentiation of MC3T3-E1 mouse osteoblasts in vitro Oral Medicine & Pathology 2011 15:45-51 DOI: 10.3353/omp.15.45

8327 Yuan Li, Xu Xu Bao, Naoki Matsuda, Ju Ming Yao, Akira Teramoto, Koji Abe & Frank K. Ko Investigation of osteoblast-like MC3T3-E1 cells on a novel recombinant collagen-like protein surface with triple helix structure Journal of Materials Science 2011 46:1396–1404 DOI: 10.1007/s10853-010-4933-2

8342 Choi EM. Honokiol isolated from Magnolia officinalis stimulates osteoblast function and inhibits the release of bone-resorbing mediators. Int Immunopharmacol 2011 11(10):1541-5 PubMed ID: 21621646 DOI: 10.1016/j.intimp.2011.05.011

8358 Zhang W, Tsurushima H, Oyane A, Yazaki Y, Sogo Y, Ito A, Matsumura A. BMP-2 gene-fibronectin-apatite composite layer enhances bone formation. J Biomed Sci 2011 18:62 PubMed ID: 21859498 DOI: 10.1186/1423-0127-18-62

8360 Jung Kyu Park Jin‐Hyung Shim Kyung Shin Kang Junseok Yeom Ho Sang Jung Jong Young Kim Keum Hong Lee Tae‐Ho Kim Shin‐Yoon Kim Dong‐Woo Cho Sei Kwang Hah Solid Free‐Form Fabrication of Tissue‐Engineering Scaffolds with a Poly(lactic‐co‐glycolic acid) Grafted Hyaluronic Acid Conjugate Encapsulating an Intact Bone Morphogenetic Protein–2/Poly(ethylene glycol) Complex Advanced Functional Materials 2011 221:2906-2912 DOI: 10.1002/adfm.201100612

8366 Ji-Hye Lee, Yu-Bin Lee, Nae-Gyune Rim, Sun-Young Jo, Youn-Mook Lim & Heungsoo Shin Development and characterization of nanofibrous poly(lactic-co-glycolic acid)/biphasic calcium phosphate composite scaffolds for enhanced osteogenic Macromolecular Research 2011 19:172–179

8374 José Antonio Gómez-Tejedor, Niek Van Overberghe, Patricia Ricoa José Luís GómezRibelles Assessment of the parameters influencing the fiber characteristics of electrospun poly (ethyl methacrylate) membranes European Polymer Journal 2011 47:119-129

8380 José Ballester-Beltrán, Patricia Rico, David Moratal, Wenlong Song, João F. Mano and Manuel Salmerón-Sánchez Role of superhydrophobicity in the biological activity of fibronectin at the cell–material interface Soft Matter 2011 7:10803-10811 DOI: 10.1039/C1SM06102J

8389 Mikami, Yoshikazu; Somei, Masanori; Watanabe, Eri; Watanabe, Nobukazu; Takahashi, Tomihisa; J. Honda, Masaki A Novel Bromomelatonin Derivative Suppresses Apoptosis with Regulating the Expression of Bcl-2 Family Genes Letters in Drug Design & Discovery 2011 8:951-956 DOI: 10.2174/157018011797655287

8391 Toru Orita, Masahiro Tomita, Katsuya Kato Regulation of Cellular Responses to Macroporous Inorganic Films Prepared by the Inverse-Opal Method Colloids Surf B Biointerfaces 2011 84:187-97 PubMed ID: 21273052 DOI: 10.1016/j.colsurfb.2010.12.032

8417 Inho Han, Barbora Vagaska, Bong Joo Park, Mi Hee Lee, Seung Jin Lee, and Jong-Chul Park Selective fibronectin adsorption against albumin and enhanced stem cell attachment on helium atmospheric pressure glow discharge treated titanium Journal of Applied Physics 2011 109:124701 DOI: 10.1063/1.3599885

8420 Yan Xiang, Yuanliang Wang, Yanfeng Luo, Bingbing Zhang, Juan Xin, Danfang Zheng Molecular Biocompatibility Evaluation of poly(D,L-lactic Acid)-Modified Biomaterials Based on Long Serial Analysis of Gene Expression Colloids Surf B Biointerfaces 2011 85 (2):248-61 PubMed ID: 21435849 DOI: 10.1016/j.colsurfb.2011.02.036

8433 Carl G Simon Jr , Yanyin Yang, Shauna M Dorsey, Murugan Ramalingam, Kaushik Chatterjee 3D Polymer Scaffold Arrays Methods Mol Biol 2011 671:161-74 PubMed ID: 20967629 DOI: 10.1007/978-1-59745-551-0_9

8434 J M Antonucci, D Skrtic PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES OF REMINERALIZING, POLYMERIC ACP COMPOSITES Polymer Prepr 2011 52(2):183-184 PubMed ID: 26456981

8437 Virginia Llopis-Hernández, Patricia Rico, José Ballester-Beltrán, David Moratal, Manuel Salmerón-Sánchez Role of Surface Chemistry in Protein Remodeling at the Cell-Material Interface PLoS One 2011 6(5):e19610 PubMed ID: 21573010 DOI: 10.1371/journal.pone.0019610

8440 Xu Xu Bao, Akira Teramoto, Koji Abe Carboxymethyl Chitosan Nonwoven Scaffold for Bone Regeneration Key Engineering Materials 2011 464:712-716 DOI: 10.4028/www.scientific.net/KEM.464.712

8443 Kai Wei, Byoung-Suhk Kim, Ick-Soo Kim Fabrication and Biocompatibility of Electrospun Silk Biocomposites Membranes (Basel) 2011 1(4):275-98 PubMed ID: 24957869 DOI: 10.3390/membranes1040275

8468 Kyu-Oh Kim, Yaeko Akada, Wei Kai, Byoung-Suhk Kim, Ick-Soo Kim Cells Attachment Property of PVA Hydrogel Nanofibers Incorporating Hyaluronic Acid for Tissue Engineering Journal of Biomaterials and Nanobiotechnology 2011 2:353-360 DOI: 10.4236/jbnb.2011.24044

8469 Kyung-Mi Chang, Eun-Mi Choi & Gun-Hee Kim Effect of selected aromatic medicinal plant sancho (Zanthoxylum schinifolium) on osteoblastic MC3T3-E1 cells Food Science and Biotechnology 2011 20:1441 DOI: 10.1007/s10068-011-0198-z

8494 Ryota Nomura, Kazuhiko Nakano, Katriina Mäkelä, Martti Vaara, Eeva Salo, Satu Alaluusua, Takashi Ooshima Isolation and Characterization of Streptococcus Mitis From Blood of Child With Osteomyelitis Int J Paediatr Dent 2011 21(3):192-9 PubMed ID: 21199004 DOI: 10.1111/j.1365-263X.2010.01110.x

8510 Do Yeon Kim, Mi Song Jung, Young Guk Park, Hai Dan Yuan, Hai Yan Quan, Sung Hyun Chung Ginsenoside Rh2(S) Induces the Differentiation and Mineralization of Osteoblastic MC3T3-E1 Cells Through Activation of PKD and p38 MAPK Pathways BMB Rep 2011 44 (10): 659-64 PubMed ID: 22026999 DOI: 10.5483/BMBRep.2011.44.10.659

8525 Do Yeon Kim, Ki Ho Park, Mi Song Jung, Bo Huang, Hai-Dan Yuan, Hai-Yan Quan, Sung Hyun Chung Ginsenoside Rh2(S) Induces Differentiation and Mineralization of MC3T3-E1 Cells Through Activation of the PKD/AMPK Signaling Pathways Int J Mol Med 2011 28(5):753-9 PubMed ID: 21769419 DOI: 10.3892/ijmm.2011.750

8567 Menemşe Gümüşderelioğlu, Sezin Aday Heparin-functionalized Chitosan Scaffolds for Bone Tissue Engineering Carbohydr Res 2011 346: 606-13 PubMed ID: 21333274 DOI: 10.1016/j.carres.2010.12.007

9205 Subhadip Bodhak, Masanori Kikuchi, Ayako Oyane, Yu Sogo, Hideo Tsurushima, Atsuo Ito Influence of Ca2+ and Mg2+ Supplementation on In Vitro Biological Properties of Hydroxyapatite/Collagen Nanocomposite Membrane Key Engineering Materials 2011 493-494:126-131 DOI: 10.4028/www.scientific.net/KEM.493-494.126

15467 Ok Hee Jeon, Yeong-Min Yoo, Kyung Hwan Kim, Christopher R. Jacobs, Chi Hyun Kim Primary Cilia-Mediated Osteogenic Response to Fluid Flow Occurs via Increases in Focal Adhesion and Akt Signaling Pathway in MC3T3-E1 Osteoblastic Cells Cellular and Molecular Bioengineering 2011 4:379-388 DOI: 10.1007/s12195-011-0191-x

15468 Toshihiko Shiraishi, Kazutaka Ohashi, Shin Morishita, Ryohei Takeuchi Investigation of Mechanism of Proliferation Promotion of Cultured Osteoblasts by Mechanical Vibration Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology 2011 2: DOI: 10.1115/imece2011-64845

15469 Asakura T, Nishi H, Nagano A, Yoshida A, Nakazawa Y, Kamiya M, Demura M. NMR analysis of the fibronectin cell-adhesive sequence, Arg-Gly-Asp, in a recombinant silk-like protein and a model peptide Biomacromolecules 2011 12(11):3910-6 PubMed ID: 21955288 DOI: 10.1021/bm2011196

15470 Toshihiko Shiraishi, Kazuhiro Sakata, Shin Morishita, Ryohei Takeuchi Investigation of a Cell Mechanosensing System by Measuring Cytoskeletal Deformation and Intracellular Calcium Ion Concentration Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology 2011 2 DOI: 10.1115/imece2011-64843

15471 Akinori Sakai, Toshitaka Nakamura Osteoblast Development in Bone Loss Due to Skeletal Unloading Mechanosensing Biology 2011 167-178 DOI: 10.1007/978-4-431-89757-6_12

8072 Lee JW, Ahn G, Kim JY, Cho DW. Evaluating cell proliferation based on internal pore size and 3D scaffold architecture fabricated using solid freeform fabrication technology. J Mater Sci Mater Med 2010 21:3195-205 PubMed ID: 20981473 DOI: 10.1007/s10856-010-4173-7

8082 Sun J, Ding Y, Lin NJ, Zhou J, Ro H, Soles CL, Cicerone MT, Lin-Gibson S. Exploring cellular contact guidance using gradient nanogratings. Biomacromolecules 2010 11:3067-72 PubMed ID: 20954734 DOI: 10.1021/bm100883m

8099 Bae J, Goto S, Mie M, Kobatake E. Construction of a thermostable cell adhesion protein for reverse transfection. J. Biotechnol. 2010 150:447-51 PubMed ID: 20934468 DOI: 10.1016/j.jbiotec.2010.09.960

8105 Ahn G, Park JH, Kang T, Lee JW, Kang HW, Cho DW. Effect of pore architecture on oxygen diffusion in 3D scaffolds for tissue engineering. J Biomech Eng 2010 132:104506 PubMed ID: 20887024 DOI: 10.1115/1.4002429

8122 Choi BH, Choi YS, Kang DG, Kim BJ, Song YH, Cha HJ. Cell behavior on extracellular matrix mimic materials based on mussel adhesive protein fused with functional peptides. Biomaterials 2010 31:8980-8 PubMed ID: 20832110 DOI: 10.1016/j.biomaterials.2010.08.027

8138 Rincon C, Chen CC, Meredith JC. Effect of poly(3-octylthiophene) doping on the attachment and proliferation of osteoblasts. Macromol Biosci 2010 10:1536-43 PubMed ID: 20803603 DOI: 10.1002/mabi.201000172

8146 Fukushima T, Ohno J, Hayakawa T, Imayoshi R, Kawaguchi M, Doi Y, Kanaya K, Mitarai M. Polycationic protamine for water-insoluble complex formation with DNA. Dent Mater J 2010 29:529-35 PubMed ID: 20733264 DOI: 10.4012/dmj.2009-131

8154 Sumitomo A, Ishino R, Urahama N, Inoue K, Yonezawa K, Hasegawa N, Horie O, Matsuoka H, Kondo T, Roeder RG, Ito M. The transcriptional mediator subunit MED1/TRAP220 in stromal cells is involved in hematopoietic stem/progenitor cell support through osteopontin expression. Mol. Cell. Biol. 2010 30:4818-27 PubMed ID: 20713445 DOI: 10.1128/MCB.01348-09

8165 Ding Y, Liang C, Yang SY, Ra JC, Choi EM, Kim JA, Kim YH. Phenolic compounds from Artemisia iwayomogi and their effects on osteoblastic MC3T3-E1 cells. Biol. Pharm. Bull. 2010 33:1448-53 PubMed ID: 20686247 DOI: 10.1248/bpb.33.1448

8173 Fujimoto K, Kiyosaki T, Mitsui N, Mayahara K, Omasa S, Suzuki N, Shimizu N. Low-intensity laser irradiation stimulates mineralization via increased BMPs in MC3T3-E1 cells. Lasers Surg Med 2010 42:519-26 PubMed ID: 20662028 DOI: 10.1002/lsm.20880

8178 Kiyosaki T, Mitsui N, Suzuki N, Shimizu N. Low-level laser therapy stimulates mineralization via increased Runx2 expression and ERK phosphorylation in osteoblasts. Photomed Laser Surg 2010 28 Suppl 1:S167-72 PubMed ID: 20649430 DOI: 10.1089/pho.2009.2693

8192 Zhang F, Koyama Y, Sanuki R, Mitsui N, Suzuki N, Kimura A, Nakajima A, Shimizu N, Maeno M. IL-17A stimulates the expression of inflammatory cytokines via celecoxib-blocked prostaglandin in MC3T3-E1 cells. Arch. Oral Biol. 2010 55:679-88 PubMed ID: 20630498 DOI: 10.1016/j.archoralbio.2010.06.003

8219 Itoh T, Takeda S, Akao Y. MicroRNA-208 modulates BMP-2-stimulated mouse preosteoblast differentiation by directly targeting V-ets erythroblastosis virus E26 oncogene homolog 1. J. Biol. Chem. 2010 285:27745-52 PubMed ID: 20576608 DOI: 10.1074/jbc.M110.105080

8225 Dhawan P, Christakos S. Novel regulation of 25-hydroxyvitamin D3 24-hydroxylase (24(OH)ase) transcription by glucocorticoids: cooperative effects of the glucocorticoid receptor, C/EBP beta, and the Vitamin D receptor in 24(OH)ase transcription. J. Cell. Biochem. 2010 110:1314-23 PubMed ID: 20564225 DOI: 10.1002/jcb.22645

8230 Yotsumoto N, Takeoka M, Yokoyama M. Tail-suspended mice lacking calponin H1 experience decreased bone loss. Tohoku J. Exp. Med. 2010 221:221-7 PubMed ID: 20551601 DOI: 10.1620/tjem.221.221

8247 Zhang F, Wang CL, Koyama Y, Mitsui N, Shionome C, Sanuki R, Suzuki N, Mayahara K, Shimizu N, Maeno M. Compressive force stimulates the gene expression of IL-17s and their receptors in MC3T3-E1 cells. Connect. Tissue Res. 2010 51:359-69 PubMed ID: 20497006 DOI: 10.3109/03008200903456942

8248 Kishimoto K, Kato A, Osada S, Nishizuka M, Imagawa M. Fad104, a positive regulator of adipogenesis, negatively regulates osteoblast differentiation. Biochem. Biophys. Res. Commun. 2010 397:187-91 PubMed ID: 20493170 DOI: 10.1016/j.bbrc.2010.05.077

8285 Rico P, Gonzalez-Garcia C, Petrie TA, Garcia AJ, Salmeron-Sanchez M. Molecular assembly and biological activity of a recombinant fragment of fibronectin (FNIII(7-10)) on poly(ethyl acrylate). Colloids Surf B Biointerfaces 2010 78:310-6 PubMed ID: 20409696 DOI: 10.1016/j.colsurfb.2010.03.019

8291 Hirai T, Kaneshige K, Kurosaki T, Nishio H. Functional expression of 5-HT2A receptor in osteoblastic MC3T3-E1 cells. Biochem. Biophys. Res. Commun. 2010 396:278-82 PubMed ID: 20399747 DOI: 10.1016/j.bbrc.2010.04.078

8304 Nakajima K, Komiyama Y, Hojo H, Ohba S, Yano F, Nishikawa N, Ihara S, Aburatani H, Takato T, Chung UI. Enhancement of bone formation ex vivo and in vivo by a helioxanthin-derivative. Biochem. Biophys. Res. Commun. 2010 395:502-8 PubMed ID: 20382113 DOI: 10.1016/j.bbrc.2010.04.041

8310 Arano T, Sato T, Matsuzaka K, Ikada Y, Yoshinari M. Osteoblastic cell proliferation with uniform distribution in a large scaffold using radial-flow bioreactor. Tissue Eng Part C Methods 2010 16:1387-98 PubMed ID: 20367244 DOI: 10.1089/ten.TEC.2009.0377

8324 Kim BJ, Choi YS, Choi BH, Lim S, Song YH, Cha HJ. Mussel adhesive protein fused with cell adhesion recognition motif triggers integrin-mediated adhesion and signaling for enhanced cell spreading, proliferation, and survival. J Biomed Mater Res A 2010 94:886-92 PubMed ID: 20336754 DOI: 10.1002/jbm.a.32768

8329 Usui Y, Uematsu T, Uchihashi T, Takahashi M, Takahashi M, Ishizuka M, Doto R, Tanaka H, Komazaki Y, Osawa M, Yamada K, Yamaoka M, Furusawa K. Inorganic polyphosphate induces osteoblastic differentiation. J. Dent. Res. 2010 89:504-9 PubMed ID: 20332330 DOI: 10.1177/0022034510363096

8344 Oya K, Tanaka Y, Moriyama Y, Yoshioka Y, Kimura T, Tsutsumi Y, Doi H, Nomura N, Noda K, Kishida A, Hanawa T. Differences in the bone differentiation properties of MC3T3-E1 cells on polished bulk and sputter-deposited titanium specimens. J Biomed Mater Res A 2010 94:611-8 PubMed ID: 20198694 DOI: 10.1002/jbm.a.32751

8348 Gonzalez-Garcia C, Sousa SR, Moratal D, Rico P, Salmeron-Sanchez M. Effect of nanoscale topography on fibronectin adsorption, focal adhesion size and matrix organisation. Colloids Surf B Biointerfaces 2010 77:181-90 PubMed ID: 20185279 DOI: 10.1016/j.colsurfb.2010.01.021

8370 Fernandes H, Dechering K, van Someren E, Steeghs I, Apotheker M, Mentink A, van Blitterswijk C, de Boer J. Effect of chordin-like 1 on MC3T3-E1 and human mesenchymal stem cells. Cells Tissues Organs (Print) 2010 191:443-52 PubMed ID: 20130390 DOI: 10.1159/000281825

8376 Yasuda Y, Tatematsu Y, Fujii S, Maeda H, Akamine A, Torabinejad M, Saito T. Effect of MTAD on the differentiation of osteoblast-like cells. J Endod 2010 36:260-3 PubMed ID: 20113785 DOI: 10.1016/j.joen.2009.11.002

8403 Kyung-Mi Chang, Eun-Mi Choi and Gun-Hee Kim Chemical constituents of Chrysanthemum indicum L. flower oil and effect on osteoblastic MC3T3-E1 cells Food Science and Biotechnology 2010 19:815-819 DOI: 10.1007/s10068-010-0114-y

8404 Yan Ding, Chun Liang, Huu Tung Nguyen, Eun Mi Choi, Jeong Ah Kim, and Young Ho Kim Chemical Constituents from Acer mandshuricum and Their Effects on the Function of Osteoblastic MC3T3-E1 Cells Bull. Korean Chem. Soc. 2010 31:929-933 DOI: 10.5012/bkcs.2010.31.04.929

8421 Rincon C, Meredith JC. Osteoblast adhesion and proliferation on poly(3-octylthiophene) thin films. Macromol Biosci 2010 10:258-64 PubMed ID: 20014196 DOI: 10.1002/mabi.200900243

8422 Sanuki R, Shionome C, Kuwabara A, Mitsui N, Koyama Y, Suzuki N, Zhang F, Shimizu N, Maeno M. Compressive force induces osteoclast differentiation via prostaglandin E(2) production in MC3T3-E1 cells. Connect. Tissue Res. 2010 51:150-8 PubMed ID: 20001844 DOI: 10.3109/03008200903168484

8428 Tseng W, Lu J, Bishop GA, Watson AD, Sage AP, Demer L, Tintut Y. Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids. J. Lipid Res. 2010 51:1010-6 PubMed ID: 19965598 DOI: 10.1194/jlr.M001099

8448 Moore NM, Lin NJ, Gallant ND, Becker ML. The use of immobilized osteogenic growth peptide on gradient substrates synthesized via click chemistry to enhance MC3T3-E1 osteoblast proliferation. Biomaterials 2010 31:1604-11 PubMed ID: 19932505 DOI: 10.1016/j.biomaterials.2009.11.011

8459 Obara M, Sakuma T, Fujikawa K. The third type III module of human fibronectin mediates cell adhesion and migration. J. Biochem. 2010 147:327-35 PubMed ID: 19880379 DOI: 10.1093/jb/mvp168

8473 Akman AC, Seda Ti?li R, Gumu?derelio?lu M, Nohutcu RM. Bone morphogenetic protein-6-loaded chitosan scaffolds enhance the osteoblastic characteristics of MC3T3-E1 cells. Artif Organs 2010 34:65-74 PubMed ID: 19821811 DOI: 10.1111/j.1525-1594.2009.00798.x

8481 Watanabe-Takano H, Takano K, Keduka E, Endo T. M-Ras is activated by bone morphogenetic protein-2 and participates in osteoblastic determination, differentiation, and transdifferentiation. Exp. Cell Res. 2010 316:477-90 PubMed ID: 19800879 DOI: 10.1016/j.yexcr.2009.09.028

8506 Hong Z, Mello A, Yoshida T, Luan L, Stern PH, Rossi A, Ellis DE, Ketterson JB. Osteoblast proliferation on hydroxyapatite coated substrates prepared by right angle magnetron sputtering. J Biomed Mater Res A 2010 93:878-85 PubMed ID: 19705463 DOI: 10.1002/jbm.a.32556

8633 Nakamura M, Nagai A, Tanaka Y, Sekijima Y, Yamashita K. Polarized hydroxyapatite promotes spread and motility of osteoblastic cells. J Biomed Mater Res A 2010 92:783-90 PubMed ID: 19274714 DOI: 10.1002/jbm.a.32404

18556 Nayrim Brizuela Guerra, Cristina González-García, Virginia Llopis, Jose Carlos Rodríguez-Hernández, David Moratal, Patricia Rico, Manuel Salmerón-Sánchez Subtle variations in polymer chemistry modulate substrate stiffness and fibronectin activity Soft Matter 2010 6:4748 DOI: 10.1039/c0sm00074d

6121 Nakamura S, Matsumoto T, Sasaki J, Egusa H, Lee KY, Nakano T, Sohmura T, Nakahira A. Effect of calcium ion concentrations on osteogenic differentiation and hematopoietic stem cell niche-related protein expression in osteoblasts. Tissue Eng Part A 2010 16(8):2467-73 PubMed ID: 20214455 DOI: 10.1089/ten.TEA.2009.0337

4738 Yuji Hatakeyama , Junko Hatakeyama , Yuriko Maruya, Kyoko Oka, Eichi Tsuruga, Tetsuichiro Inai and Yoshihiko Sawa Growth Differentiation Factor 5 (GDF-5) Induces Matrix Metalloproteinase 2 (MMP-2) Expression in Periodontal Ligament Cells and Modulates MMP-2 and MMP-13 Activity in Osteoblasts. Bone and Tissue Regeneration Insights 2010 4:1-10 DOI: 10.4137/BTRI.S8120

7972 Wang X, Ito A, Sogo Y, Li X, Oyane A. Silicate-apatite composite layers on external fixation rods and in vitro evaluation using fibroblast and osteoblast. J Biomed Mater Res A 2010 92(3):1181-9 PubMed ID: 19322819 DOI: 10.1002/jbm.a.32436

7992 Hsien-Te Chen, Chi-Jen Chung, Tsai-Ching Yang, I-Ping Chiang, Chin-Hsin Tang, Keh-Chang Chen, Ju-Liang He Osteoblast growth behavior on micro-arc oxidized β-titanium alloy Surface and Coatings Technology 2010 205:1624-1629 DOI: 10.1016/j.surfcoat.2010.07.027

8187 Xu Xu Bao, Yuan Li, Akira Teramoto, Koji Abe Carboxymethyl Chitosan/Hydroxyapatite Composite Scaffold for Bone Regeneration Advanced Materials Research 2010 123-125:299-302 DOI: 10.4028/www.scientific.net/AMR.123-125.299

8189 Shinoda Y, Kawaguchi H, Higashikawa A, Hirata M, Miura T, Saito T, Nakamura K, Chung UI, Ogata N. Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells. J Cell Biochem 2010 109(4):755-63 PubMed ID: 20058231 DOI: 10.1002/jcb.22454

8190 Jun-Ichi Sasaki, Takuya Matsumoto, Hiroshi Egusa, Takayoshi Nakano, Takuya Ishimoto, Taiji Sohmura and Hirofumi Yatani In vitro engineering of transitional tissue by patterning and functional control of cells in fibrin gel Soft Matter 2010 6:1662-1667 DOI: 10.1039/B922418A

8191 Young Min Shin, Heungsoo Shin & Youn Mook Lim Surface modification of electrospun poly(L-lactide-co-ɛ-caprolactone) fibrous meshes with a RGD peptide for the control of adhesion, proliferation and differentiation of the preosteoblastic cells Macromolecular Research 2010 18:472–481 DOI: 10.1007/s13233-010-0507-z

8194 Xiupeng Wang, Xia Li a, Kazuo Onuma, Atsuo Ito, Yu Sogo, Katsunori Kosuge and Ayako Oyane Mesoporous bioactive glass coatings on stainless steel for enhanced cell activity, cytoskeletal organization and AsMg immobilization J Mater Chem 2010 20:6437-6445 DOI: 10.1039/C0JM00399A

8195 Widyowati R, Tezuka Y, Miyahara T, Awale S, Kadota S. Alkaline phosphatase (ALP) enhancing iridoid glucosides from the Indonesian medicinal plant Barleria lupulina. Nat Prod Commun 2010 5(11):1711-6 PubMed ID: 21213964

8197 Takaaki ArahiraMitsugu Todo Effects of osteoblast-like cell seeding on mechanical properties of porous composite scaffolds 6th World Congress of Biomechanics (WCB 2010) 2010 1234-1237 DOI: 10.1007/978-3-642-14515-5_313

8200 Megumi FUSE, Tohru HAYAKAWA, Masahiko FUKUMOTO, Masaharu MAKIMURA Effect of fibronectin immobilization on poly-L-lactic acid films for the adhesion and proliferation of mouse osteoblast-like cells Nano Biomedicine 2010 2:93-102 DOI: 10.11344/nano.2.93

8201 Sasaki J, Asoh TA, Matsumoto T, Egusa H, Sohmura T, Alsberg E, Akashi M, Yatani H. Fabrication of three-dimensional cell constructs using temperature-responsive hydrogel. Tissue Eng Part A 2010 16(8):2497-504 PubMed ID: 20218862 DOI: 10.1089/ten.TEA.2009.0523

8207 Kaori Yoshino, Kaoru Saijo, Chikako Noro and Yukio Nakamura Development of a simple method to determine the mouse strain from which cultured cell lines originated Interdisciplinary Bio Central 2010 2:0014 DOI: 10.4051/ibc.2010.2.4.0014

8212 Chatterjee K, Lin-Gibson S, Wallace WE, Parekh SH, Lee YJ, Cicerone MT, Young MF, Simon CG Jr. The effect of 3D hydrogel scaffold modulus on osteoblast differentiation and mineralization revealed by combinatorial screening. Biomaterials 2010 31(19):5051-62 PubMed ID: 20378163 DOI: 10.1016/j.biomaterials.2010.03.024

8235 Kawamori Y, Katayama Y, Asada N, Minagawa K, Sato M, Okamura A, Shimoyama M, Nakagawa K, Okano T, Tanimoto M, Kato S, Matsui T. Role for vitamin D receptor in the neuronal control of the hematopoietic stem cell niche. Blood 2010 116(25):5528-35 PubMed ID: 20813899 DOI: 10.1182/blood-2010-04-279216

8236 Zhou WY, Guo B, Liu M, Liao R, Rabie AB, Jia D. Poly(vinyl alcohol)/halloysite nanotubes bionanocomposite films: Properties and in vitro osteoblasts and fibroblasts response. J Biomed Mater Res A. 2010 93(4):1574-87 PubMed ID: 20014291 DOI: 10.1002/jbm.a.32656

8255 Inoue M, Rodriguez AP, Takagi T, Katase N, Kubota M, Nagai N, Nagatsuka H, Inoue M, Nagaoka N, Takagi S, Suzuki K. Effect of a new titanium coating material (CaTiO3-aC) prepared by thermal decomposition method on osteoblastic cell response. J Biomater Appl 2010 24(7):657-72 PubMed ID: 19726530 DOI: 10.1177/0885328209340334

8256 Eun-Hye Lee, Yoshiki Kamigaito, Takashi Tsujimoto, Shu Seki, Hiroshi Uyama, Seiichi Tagawa, Moon-Hee Sung Preparation of Poly (γ-glutamic acid) Hydrogel/Apatite Composites and Their Application forScaffold of Cell Proliferation SENI　GAKKAISHI 2010 66:104-111 DOI: 10.2115/fiber.66.104

8262 Zhao J, Ohba S, Komiyama Y, Shinkai M, Chung UI, Nagamune T. Icariin: a potential osteoinductive compound for bone tissue engineering. Tissue Eng Part A 2010 16(1):233-43 PubMed ID: 19698057 DOI: 10.1089/ten.TEA.2009.0165

8266 Takeuchi K, Abe M, Hiasa M, Oda A, Amou H, Kido S, Harada T, Tanaka O, Miki H, Nakamura S, Nakano A, Kagawa K, Yata K, Ozaki S, Matsumoto T. Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth. PLoS One 2010 5(3):e9870 PubMed ID: 20360846 DOI: 10.1371/journal.pone.0009870

8271 Sezin Aday Menemşe Gümüşderelioğlu Bone‐like apatite‐coated chitosan scaffolds: Characterization and osteoblastic activity Polymer Composites 2010 31:1418-1426 DOI: 10.1002/pc.20927

15466 Toshihiko Shiraishi, Kazuhiro Sakata, Shin Morishita, Ryohei Takeuchi Visualization of Actin Fibers in a Living Osteoblast Under Shear Deformation Biomedical and Biotechnology Engineering 2010 2 DOI: 10.1115/imece2010-39810

15690 M. Lebourg, J. Suay Antón, J.L. Gomez Ribelles Characterization of calcium phosphate layers grown on polycaprolactone for tissue engineering purposes Composites Science and Technology 2010 70:1796-1804 DOI: 10.1016/j.compscitech.2010.07.017

8408 Sailon AM, Allori AC, Davidson EH, Reformat DD, Allen RJ, Warren SM. A novel flow-perfusion bioreactor supports 3D dynamic cell culture. J. Biomed. Biotechnol. 2009 2009:873816 PubMed ID: 20037739 DOI: 10.1155/2009/873816

8410 Hsien-Te Chena, Ching-Hung Hsiaoa, Han-Yun Longa, Chi- Jen Chungc, Chih-Hsin Tangd, Keh-Chang Chena, Ju-Liang Hea Micro-arc oxidation of β-titanium alloy: Structural characterization and osteoblast compatibility Surface and Coatings Technology 2009 204:1126-1131 DOI: 10.1016/j.surfcoat.2009.06.043

8441 Kamon M, Zhao R, Sakamoto K. Green tea polyphenol (-)-epigallocatechin gallate suppressed the differentiation of murine osteoblastic MC3T3-E1 cells. Cell Biol. Int. 2009 34:109-16 PubMed ID: 19947947 DOI: 10.1042/CBI20090011

8444 Hsi-Kai Tsoua, Ping- Yen Hsieha, Chi-Jen Chung, Chih-Hsin Tang, Tien-Wei Shyr, ju-LiangHe Low-temperature deposition of anatase TiO2 on medical grade polyetheretherketone to assist osseous integration Surface and Coatings Technology 2009 204:1121-1125 DOI: 10.1016/j.surfcoat.2009.06.018

8451 Takahashi S, Yamazoe H, Sassa F, Suzuki H, Fukuda J. Preparation of coculture system with three extracellular matrices using capillary force lithography and layer-by-layer deposition. J. Biosci. Bioeng. 2009 108:544-50 PubMed ID: 19914591 DOI: 10.1016/j.jbiosc.2009.06.013

8483 LEE Seung-Jae, LEE In Hwan, PARK Jeong Hun, GWAK So-Jung, RHIE Jong-Won, CHO Dong-Woo, KO Tae Jo & KIM Dong Sung Development of a hybrid scaffold and a bioreactor for cartilage regeneration Chinese Science Bulletin 2009 54:3608-3612 DOI: 10.1007/s11434-009-0602-8

8498 Yamasaki K, Hagiwara H. Excess iron inhibits osteoblast metabolism. Toxicol. Lett. 2009 191:211-5 PubMed ID: 19735707 DOI: 10.1016/j.toxlet.2009.08.023

8501 Kasai T, Bandow K, Suzuki H, Chiba N, Kakimoto K, Ohnishi T, Kawamoto S, Nagaoka E, Matsuguchi T. Osteoblast differentiation is functionally associated with decreased AMP kinase activity. J. Cell. Physiol. 2009 221:740-9 PubMed ID: 19725053 DOI: 10.1002/jcp.21917

8507 Yang JY, Jung JY, Cho SW, Choi HJ, Kim SW, Kim SY, Kim HJ, Jang CH, Lee MG, Han J, Shin CS. Chloride intracellular channel 1 regulates osteoblast differentiation. Bone 2009 45:1175-85 PubMed ID: 19703605 DOI: 10.1016/j.bone.2009.08.012

8508 Fernandes H, Dechering K, Van Someren E, Steeghs I, Apotheker M, Leusink A, Bank R, Janeczek K, Van Blitterswijk C, de Boer J. The role of collagen crosslinking in differentiation of human mesenchymal stem cells and MC3T3-E1 cells. Tissue Eng Part A 2009 15:3857-67 PubMed ID: 19694522 DOI: 10.1089/ten.tea.2009.0011

8524 Akihisa Kamikawa, Ying Li, Yoshimitsu Abiko Hydrogen Peroxide Reduced Osteomodulin Gene Expression in MC3T3-E1 J Hard Tissue Biology 2009 18:59-62 DOI: 10.2485/jhtb.18.59

8538 Okamoto A, Ohnishi T, Bandow K, Kakimoto K, Chiba N, Maeda A, Fukunaga T, Miyawaki S, Matsuguchi T. Reduction of orthodontic tooth movement by experimentally induced periodontal inflammation in mice. Eur. J. Oral Sci. 2009 117:238-47 PubMed ID: 19583750 DOI: 10.1111/j.1600-0722.2009.00625.x

8565 Nagata A, Tanaka T, Minezawa A, Poyurovsky M, Mayama T, Suzuki S, Hashimoto N, Yoshida T, Suyama K, Miyata A, Hosokawa H, Nakayama T, Tatsuno I. cAMP activation by PACAP/VIP stimulates IL-6 release and inhibits osteoblastic differentiation through VPAC2 receptor in osteoblastic MC3T3 cells. J. Cell. Physiol. 2009 221:75-83 PubMed ID: 19496170 DOI: 10.1002/jcp.21831

8572 Itoh T, Nozawa Y, Akao Y. MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5. J. Biol. Chem. 2009 284:19272-9 PubMed ID: 19454767 DOI: 10.1074/jbc.M109.014001

8581 Maki M, Miyazaki H, Niisato N, Morihara T, Marunaka Y, Kubo T. Blockers of K+/Cl- transporter/channels diminish proliferation of osteoblastic cells. Biomed. Res. 2009 30:137-40 PubMed ID: 19420738 DOI: 10.2220/biomedres.30.137

8587 Tung NH, Ding Y, Choi EM, Van Kiem P, Van Minh C, Kim YH. New anthracene glycosides from Rhodomyrtus tomentosa stimulate osteoblastic differentiation of MC3T3-E1 cells. Arch. Pharm. Res. 2009 32:515-20 PubMed ID: 19407968 DOI: 10.1007/s12272-009-1406-8

8588 Nakao Y, Koike T, Ohta Y, Manaka T, Imai Y, Takaoka K. Parathyroid hormone enhances bone morphogenetic protein activity by increasing intracellular 3', 5'-cyclic adenosine monophosphate accumulation in osteoblastic MC3T3-E1 cells. Bone 2009 44:872-7 PubMed ID: 19442611 DOI: 10.1016/j.bone.2009.01.370

8618 Jin Woo Leea, GeunSeon Ahna, Dae Shick Kimb, Dong-Woo Cho Development of nano- and microscale composite 3D scaffolds using PPF/DEF-HA and micro-stereolithography Microelectronic Engineering 2009 86:1465-1467 DOI: 10.1016/j.mee.2008.12.038

8628 Dorsey SM, Lin-Gibson S, Simon CG Jr. X-ray microcomputed tomography for the measurement of cell adhesionand proliferation in polymer scaffolds. Biomaterials 2009 30:2967-74 PubMed ID: 19286251 DOI: 10.1016/j.biomaterials.2009.02.032

8629 Hou CH, Lin J, Huang SC, Hou SM, Tang CH. Ultrasound stimulates NF-kappaB activation and iNOS expression via the Ras/Raf/MEK/ERK signaling pathway in cultured preosteoblasts. J. Cell. Physiol. 2009 220:196-203 PubMed ID: 19288477 DOI: 10.1002/jcp.21751

8632 Kinugawa M, Fukuzawa S, Tachibana K. Skeletal protein protection: the mode of action of an anti-osteoporotic marine alkaloid, norzoanthamine. J. Bone Miner. Metab. 2009 27:303-14 PubMed ID: 19277454 DOI: 10.1007/s00774-009-0049-7

8634 Raynor JE, Petrie TA, Fears KP, Latour RA, Garcia AJ, Collard DM. Saccharide polymer brushes to control protein and cell adhesion to titanium. Biomacromolecules 2009 10:748-55 PubMed ID: 19271753 DOI: 10.1021/bm8011924

8638 Cho SW, Yang JY, Sun HJ, Jung JY, Her SJ, Cho HY, Choi HJ, Kim SW, Kim SY, Shin CS. Wnt inhibitory factor (WIF)-1 inhibits osteoblastic differentiation in mouse embryonic mesenchymal cells. Bone 2009 44:1069-77 PubMed ID: 19254785 DOI: 10.1016/j.bone.2009.02.012

8645 Yuan Q, Kubo T, Doi K, Morita K, Takeshita R, Katoh S, Shiba T, Gong P, Akagawa Y. Effect of combined application of bFGF and inorganic polyphosphate on bioactivities of osteoblasts and initial bone regeneration. Acta Biomater 2009 5:1716-24 PubMed ID: 19251495 DOI: 10.1016/j.actbio.2009.01.034

8649 Siddappa R, Mulder W, Steeghs I, van de Klundert C, Fernandes H, Liu J, Arends R, van Blitterswijk C, de Boer J. cAMP/PKA signaling inhibits osteogenic differentiation and bone formation in rodent models. Tissue Eng Part A 2009 15:2135-43 PubMed ID: 19231969 DOI: 10.1089/ten.tea.2008.0512

8656 Wada Y, Mizuno M, Tamura M. Enamel matrix derivative neutralized the effect of lipopolysaccharide on osteoprotegerin and receptor activator of nuclear factor kappa B ligand expression of osteoblasts. Arch. Oral Biol. 2009 54:306-12 PubMed ID: 19201394 DOI: 10.1016/j.archoralbio.2009.01.004

8662 Yoshida T, Clark MF, Stern PH. The small GTPase RhoA is crucial for MC3T3-E1 osteoblastic cell survival. J. Cell. Biochem. 2009 106:896-902 PubMed ID: 19184980 DOI: 10.1002/jcb.22059

8664 Lovmand J, Justesen J, Foss M, Lauridsen RH, Lovmand M, Modin C, Besenbacher F, Pedersen FS, Duch M. The use of combinatorial topographical libraries for the screening of enhanced osteogenic expression and mineralization. Biomaterials 2009 30:2015-22 PubMed ID: 19178942 DOI: 10.1016/j.biomaterials.2008.12.081

8671 Tung NH, Ding Y, Choi EM, Minh CV, Kim YH. New neolignan component from Camellia amplexicaulis and effects on osteoblast differentiation. Chem. Pharm. Bull. 2009 57:65-8 PubMed ID: 19122318 DOI: 10.1248/cpb.57.65

8685 Tohru Hayakawa, Chihiro Mochizuki, Hiroki Hara, Tadao Fukushima, Fei Yang, Hong Shen, Shenguo Wang, Mitsunobu Sato Influence of Apatite Crystallinity in Porous PLGA/Apatite Composite Scaffold on Cortical Bone Response J Hard Tissue Biology 2009 18:7-12

8686 Yasuhiro Tanimoto, Yo Shibata, Asuka Murakami, Takashi Miyazaki, Norihiro Nishiyama Effect of Varying HAP/TCP Ratios in Tape-cast Biphasic Calcium Phosphate Ceramics on Response In Vitro J Hard Tissue Biology 2009 18:71-76 DOI: 10.2485/jhtb.18.71

8692 Kim YH, Choi EM. Stimulation of osteoblastic differentiation and inhibition of interleukin-6 and nitric oxide in MC3T3-E1 cells by pomegranate ethanol extract. Phytother Res 2009 23:737-9 PubMed ID: 19107859 DOI: 10.1002/ptr.2587

8708 Matsuguchi T, Chiba N, Bandow K, Kakimoto K, Masuda A, Ohnishi T. JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation. J. Bone Miner. Res. 2009 24:398-410 PubMed ID: 19016586 DOI: 10.1359/jbmr.081107

8766 Yamachika E, Tsujigiwa H, Shirasu N, Ueno T, Sakata Y, Fukunaga J, Mizukawa N, Yamada M, Sugahara T. Immobilized recombinant human bone morphogenetic protein-2 enhances the phosphorylation of receptor-activated Smads. J Biomed Mater Res A 2009 88:599-607 PubMed ID: 18314893 DOI: 10.1002/jbm.a.31833

6536 Kanamoto T, Mizuhashi K, Terada K, Minami T, Yoshikawa H, Furukawa T. Isolation and characterization of a novel plasma membrane protein, osteoblast induction factor (obif), associated with osteoblast differentiation. BMC Dev Biol 2009 9:70 PubMed ID: 20025746 DOI: 10.1186/1471-213X-9-70

7575 Oya K, Tanaka Y, Saito H, Kurashima K, Nogi K, Tsutsumi H, Tsutsumi Y, Doi H, Nomura N, Hanawa T. Calcification by MC3T3-E1 cells on RGD peptide immobilized on titanium through electrodeposited PEG. Biomaterials. 2009 30(7):1281-6 PubMed ID: 19091397 DOI: 10.1016/j.biomaterials.2008.11.030

7880 Bu SY, Hunt TS, Smith BJ. Dried plum polyphenols attenuate the detrimental effects of TNF-alpha on osteoblast function coincident with up-regulation of Runx2, Osterix and IGF-I. J Nutr Biochem 2009 20(1):35-44 PubMed ID: 18495459 DOI: 10.1016/j.jnutbio.2007.11.012

7942 Nakai T, Yoshimura Y, Deyama Y, Suzuki K, Iida J. Mechanical stress up-regulates RANKL expression via the VEGF autocrine pathway in osteoblastic MC3T3-E1 cells. Mol Med Rep 2009 2(2):229-34 PubMed ID: 21475817 DOI: 10.3892/mmr_00000088

7961 Wang X, Ito A, Sogo Y, Li X, Tsurushima H, Oyane A. Ascorbate-apatite composite and ascorbate-FGF-2-apatite composite layers formed on external fixation rods and their effects on cell activity in vitro. Acta Biomater 2009 5(7):2647-56 PubMed ID: 19375998 DOI: 10.1016/j.actbio.2009.03.020

7973 Tokuda S, Obata A, Kasuga T. Preparation of poly(lactic acid)/siloxane/calcium carbonate composite membranes with antibacterial activity. Acta Biomater 2009 5(4):1163-8 PubMed ID: 18996778 DOI: 10.1016/j.actbio.2008.10.005

7985 Ding Y, Nguyen HT, Choi EM, Bae K, Kim YH. Rhusonoside A, a new megastigmane glycoside from Rhus sylvestris, increases the function of osteoblastic MC3T3-E1 cells. Planta Med 2009 75(2):158-62 PubMed ID: 19053017 DOI: 10.1055/s-0028-1088373

7989 Yun SI, Yoon HY, Jeong SY, Chung YS. Glucocorticoid induces apoptosis of osteoblast cells through the activation of glycogen synthase kinase 3beta. J Bone Miner Metab 2009 27(2):140-8 PubMed ID: 19066717 DOI: 10.1007/s00774-008-0019-5

7991 Jin WooLee, Jin Hwa Jung, Dae Shick Kim, Geunbae Lim, Dong-Woo Cho Estimation of cell proliferation by various peptide coating at the PPF/DEF 3D scaffold Microelectronic Engineering 2009 86:1451-1454 DOI: 10.1016/j.mee.2008.12.052

10145 Murakami M, Kawachi H, Ogawa K, Nishino Y, Funaba M. Receptor expression modulates the specificity of transforming growth factor-beta signaling pathways. Genes Cells 2009 14(4):469-82 PubMed ID: 19335617 DOI: 10.1111/j.1365-2443.2009.01283.x

7993 Akiyama H, Furukawa S, Wakisaka S, Maeda T. Elevated expression of CTRP3/cartducin contributes to promotion of osteosarcoma cell proliferation. Oncol Rep 2009 21(6):1477-81 PubMed ID: 19424626 DOI: 10.3892/or_00000377

7994 Zheng Z, Zhang L, Kong L, Wang A, Gong Y, Zhang X. The behavior of MC3T3-E1 cells on chitosan/poly-L-lysine composite films: effect of nanotopography, surface chemistry, and wettability. J Biomed Mater Res A 2009 89(2):453-65 PubMed ID: 18431777 DOI: 10.1002/jbm.a.31979

8008 Mariona Rabionet Jay Arre Toque Ari Ide‐Ektessabi In vitro evaluation of osteoblast‐like cells on hydroxyapatite‐coated porous stainless steel implants by synchrotron radiation x‐ray fluorescence X-Ray Spectrometry 2009 38:278-282 DOI: 10.1002/xrs.1164

8009 Chiaki HIWA, Yoshikazu NAKAI, Nobuo TANAKA, Taiji ADACHI, Masaki HOJO, Shunsuke BABA 512 Evaluation of Mechanical and Cell-proliferative Properties on In vitro Using Different types of Biodegradable Polymer as Scaffold The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2009 2008.21:207-208 DOI: 10.1299/jsmebio.2008.21.207

8013 Higuchi C, Nakamura N, Yoshikawa H, Itoh K. Transient dynamic actin cytoskeletal change stimulates the osteoblastic differentiation. J Bone Miner Metab 2009 27(2):158-67 PubMed ID: 19183835 DOI: 10.1007/s00774-009-0037-y

8014 Takeshi Hagio, Tomohiko Tanase, Jun Akiyama, Masanori Umino, Kazuhiko Iwai, Shigeo Asai Difference in bioactivity, initial cell attachment and cell morphology observed on the surface of hydroxyapatite ceramics with controlled orientation MATERIALS TRANSACTIONS 2009 50:734-739 DOI: 10.2320/matertrans.MBW200836

8032 Yamazaki M, Fukushima H, Shin M, Katagiri T, Doi T, Takahashi T, Jimi E. Tumor necrosis factor alpha represses bone morphogenetic protein (BMP) signaling by interfering with the DNA binding of Smads through the activation of NF-kappaB. J Biol Chem 2009 284(51):35987-95 PubMed ID: 19854828 DOI: 10.1074/jbc.M109.070540

8034 Wu PH1, Arce SH, Burney PR, Tseng Y. A novel approach to high accuracy of video-based microrheology. Biophys J. 2009 96(12):5103-11 PubMed ID: 19527670 DOI: 10.1016/j.bpj.2009.03.029

8037 Lin NJ, Lin-Gibson S. Osteoblast response to dimethacrylate composites varying in composition, conversion and roughness using a combinatorial approach. Biomaterials 2009 30(27):4480-7 PubMed ID: 19520423 DOI: 10.1016/j.biomaterials.2009.05.019

8086 Hayashi C, Hasegawa U, Saita Y, Hemmi H, Hayata T, Nakashima K, Ezura Y, Amagasa T, Akiyoshi K, Noda M. Osteoblastic bone formation is induced by using nanogel-crosslinking hydrogel as novel scaffold for bone growth factor. J Cell Physiol 2009 220(1):1-7 PubMed ID: 19301257 DOI: 10.1002/jcp.21760

8089 Zheng Z, Wei Y, Wang G, Gong Y, Zhang X. Surface characterization and cytocompatibility of three chitosan/polycation composite membranes for guided bone regeneration. J Biomater Appl 2009 24(3):209-29 PubMed ID: 18987023 DOI: 10.1177/0885328208095825

8103 Young-Joon Seol, Jong Young Kim, Eui Kyun Park, Shin-YoonKim, Dong-Woo Cho Fabrication of a hydroxyapatite scaffold for bone tissue regeneration using microstereolithography and molding technology Microelectronic Engineering 2009 86:1443-1446 DOI: 10.1016/j.mee.2009.01.053

8123 Cheung CL, Chan BY, Chan V, Ikegawa S, Kou I, Ngai H, Smith D, Luk KD, Huang QY, Mori S, Sham PC, Kung AW. Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. Hum Mol Genet 2009 18(4):679-87 PubMed ID: 19064610 DOI: 10.1093/hmg/ddn397

8131 Mavis B, Demirtaş TT, Gümüşderelioğlu M, Gündüz G, Colak U. Synthesis, characterization and osteoblastic activity of polycaprolactone nanofibers coated with biomimetic calcium phosphate. Acta Biomater 2009 5(8):3098-111 PubMed ID: 19426840 DOI: 10.1016/j.actbio.2009.04.037

8140 Aamer KA, Genson KL, Kohn J, Becker ML. Impact of polymer-bound iodine on fibronectin adsorption and osteoblast cell morphology in radiopaque medical polymers: tyrosine-derived polycarbonate blends as a model system. Biomacromolecules 2009 10(9):2418-26 PubMed ID: 19645443 DOI: 10.1021/bm900327b

8141 Rodríguez Hernández JC, Rico P, Moratal D, Monleón Pradas M, Salmerón-Sánchez M. Fibrinogen patterns and activity on substrates with tailored hydroxy density. Macromol Biosci 2009 ;9(8):766-75 PubMed ID: 19422014 DOI: 10.1002/mabi.200800332

8145 Işil Gerçek Beşkardeş, Menemşe Gümüşderelioğlu Biomimetic Apatite-coated PCL Scaffolds: Effect of Surface Nanotopography on Cellular Functions Journal of Bioactive and Compatible Polymers 2009 24:507-524 DOI: 10.1177/0883911509349311

15463 Seung-Jae Lee, Jeong Hun Park, Yong-Joon Seol, In Hwan Lee, Sang Soon Kang, Dong-Woo Cho Development of a bioreactor for the mechanical stimulation of agarose hydrogels Microelectronic Engineering 2009 86:1411-1415 DOI: 10.1016/j.mee.2009.02.026

15464 Toshihiko Shiraishi, Tetsuo Shikata, Shin Morishita, Ryohei Takeuchi Investigation of Promotion of Bone Matrices in Cultured Osteoblasts by Mechanical Vibration Biomedical and Biotechnology Engineering 2009 2 DOI: 10.1115/imece2009-11131

15465 Yin Tintut Oxidized Phospholipids Regulate Interleukin-6 Expression via the Protein Kinase A and Extracellular Signal-regulated Pathways in Osteoblasts The UCLA USJ 2009 22:57-64

17406 Li X, Ominsky MS, Warmington KS, Morony S, Gong J, Cao J, Gao Y, Shalhoub V, Tipton B, Haldankar R, Chen Q, Winters A, Boone T, Geng Z, Niu QT, Ke HZ, Kostenuik PJ, Simonet WS, Lacey DL, Paszty C. Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis J Bone Miner Res 2009 24(4):578-88 PubMed ID: 19049336 DOI: 10.1359/jbmr.081206

8714 Yamamichi N, Pugdee K, Chang WJ, Lee SY, Yoshinari M, Hayakawa T, Abiko Y. Gene expression monitoring in osteoblasts on titanium coated with fibronectin-derived peptide. Dent Mater J 2008 27:744-50 PubMed ID: 18972793 DOI: 10.4012/dmj.27.744

8724 Schulz RM, Wustneck N, van Donkelaar CC, Shelton JC, Bader A. Development and validation of a novel bioreactor system for load- and perfusion-controlled tissue engineering of chondrocyte-constructs. Biotechnol. Bioeng. 2008 101:714-28 PubMed ID: 18814291 DOI: 10.1002/bit.21955

8727 Yamauchi M, Kawai S, Kato T, Ooshima T, Amano A. Odd-skipped related 1 gene expression is regulated by Runx2 and Ikzf1 transcription factors. Gene 2008 426:81-90 PubMed ID: 18804520 DOI: 10.1016/j.gene.2008.08.015

8734 Van Kiem P, Quang TH, Huong TT, Nhung le TH, Cuong NX, Van Minh C, Choi EM, Kim YH. Chemical constituents of Acanthus ilicifolius L. and effect on osteoblastic MC3T3E1 cells. Arch. Pharm. Res. 2008 31:823-9 PubMed ID: 18704321 DOI: 10.1007/s12272-001-1232-3

8743 Cuong NX, Tuan TA, Kiem PV, Minh CV, Choi EM, Kim YH. New cembranoid diterpenes from the Vietnamese soft coral Sarcophyton mililatensis stimulate osteoblastic differentiation in MC3T3-E1 cells. Chem. Pharm. Bull. 2008 56:988-92 PubMed ID: 18591816 DOI: 10.1248/cpb.56.988

8779 Ohki TOMOMATSU, Akira TACHIBANA, Kiyoshi YAMAUCHI and Toshizumi TANABE A film of collagen/calcium phosphate composite prepared by enzymatic mineralization in an aqueous phase J The Ceramic Society of Japan 2008 116:10-13 DOI: 10.2109/jcersj2.116.10

6300 Shimomura-Kuroki J, Ubaidus S, Hl Freitas P, Li M, Ishida Y, Saito N, Oda K, Shimooka S, Amizuka N. Rat wild-type parathyroid hormone receptor (PTH-R) and mutant PTH-R(P132L) show the different intracellular localization in vitro. Biomed Res 2008 29(2):61-9 PubMed ID: 18480546 DOI: 10.2220/biomedres.29.61

6521 Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H. Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9. J Biol Chem 2008 283(36):24682-9 PubMed ID: 18617520 DOI: 10.1074/jbc.M709857200

6528 Arai K, Nagashima Y, Takemoto T, Nishiyama T. Mechanical strain increases expression of type XII collagen in murine osteoblastic MC3T3-E1 cells. Cell Struct Funct 2008 33(2):203-10 PubMed ID: 18957791 DOI: 10.1247/csf.08025

6529 Miyazaki T, Miyauchi S, Tawada A, Anada T, Matsuzaka S, Suzuki O. Oversulfated chondroitin sulfate-E binds to BMP-4 and enhances osteoblast differentiation. J Cell Physiol 2008 217(3):769-77 PubMed ID: 18720384 DOI: 10.1002/jcp.21557

7647 Ozeki K, Aoki H, Fukui Y. The effect of adsorbed vitamin D and K to hydroxyapatite on ALP activity of MC3T3-E1 cell. J Mater Sci Mater Med 2008 19(4):1753-7 PubMed ID: 17943413 DOI: 10.1007/s10856-007-3288-y

7660 Tamura D, Hiraga T, Myoui A, Yoshikawa H, Yoneda T. Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone. Int J Oncol 2008 33(1):17-24 PubMed ID: 18575746

7697 Xu HH, Weir MD, Simon CG. Injectable and strong nano-apatite scaffolds for cell/growth factor delivery and bone regeneration. Dent Mater 2008 24(9):1212-22 PubMed ID: 18359072 DOI: 10.1016/j.dental.2008.02.001

7709 Wong RW, Rabie AB. Effect of quercetin on preosteoblasts and bone defects. Open Orthop J 2008 2:27-32 PubMed ID: 19461927 DOI: 10.2174/1874325000802010027

7715 Maekawa K, Yoshida Y, Mine A, van Meerbeek B, Suzuki K, Kuboki T. Effect of polyphosphoric acid pre-treatment of titanium on attachment, proliferation, and differentiation of osteoblast-like cells (MC3T3-E1). Clin Oral Implants Res 2008 19(3):320-5 PubMed ID: 18190561 DOI: 10.1111/j.1600-0501.2007.01477.x

7716 Chen RI, Gallant ND, Smith JR, Kipper MJ, Simon CG Jr. Time-dependent effects of pre-aging polymer films in cell culture medium on cell adhesion and spreading. J Mater Sci Mater Med 2008 19(4):1759-66 PubMed ID: 18049876 DOI: 10.1007/s10856-007-3309-x

7723 Cho SW, Her SJ, Sun HJ, Choi OK, Yang JY, Kim SW, Kim SY, Shin CS. Differential effects of secreted frizzled-related proteins (sFRPs) on osteoblastic differentiation of mouse mesenchymal cells and apoptosis of osteoblasts. Biochem Biophys Res Commun 2008 367(2):399-405 PubMed ID: 18166153 DOI: 10.1016/j.bbrc.2007.12.128

7724 Tetsuo SHIKATA, Toshihiko SHIRAISHI, Shin MORISHITA, Ryohei TAKEUCHI, Tomoyuki SAITO Effects of amplitude and frequency of mechanical vibration stimulation on cultured osteoblasts Journal of System Design and Dynamics 2008 2:382-388 DOI: 10.1299/jsdd.2.382

7730 Zhao J, Ohba S, Shinkai M, Chung UI, Nagamune T. Icariin induces osteogenic differentiation in vitro in a BMP- and Runx2-dependent manner. Biochem Biophys Res Commun 2008 369(2):444-8 PubMed ID: 18295595 DOI: 10.1016/j.bbrc.2008.02.054

7740 Yong HUANG, Yingjun WANG, Chengyun NING, Kaihui NANa, Yong HAN Preparation and properties of a cerium-containing hydroxyapatite coating on commercially pure titanium by micro-arc oxidation Rare Metals 2008 27:257-260 DOI: 10.1016/S1001-0521(08)60125-4

7748 Eelen G, Vanden Bempt I, Verlinden L, Drijkoningen M, Smeets A, Neven P, Christiaens MR, Marchal K, Bouillon R, Verstuyf A. Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy. Oncogene 2008 ;27(30):4233-41 PubMed ID: 18345034 DOI: 10.1038/onc.2008.51

7768 Jie Mo Tian, Li Min Dong, Chen Wang, Zhi Ping Guo, Chao Zong Zhang, Qing Fen Zan, Xian Gang Wang Tissue engineering scaffolds of bioceramics and new bone growth Key Engineering Materials 2008 368-372:1161-1165 DOI: 10.4028/www.scientific.net/KEM.368-372.1161

7772 Morgan AW, Roskov KE, Lin-Gibson S, Kaplan DL, Becker ML, Simon CG Jr. Characterization and optimization of RGD-containing silk blends to support osteoblastic differentiation. Biomaterials 2008 29(16):2556-63 PubMed ID: 18325585 DOI: 10.1016/j.biomaterials.2008.02.007

7775 Saito K, Konishi I, Nishiguchi M, Hoshino T, Fujiwara T. Amelogenin binds to both heparan sulfate and bone morphogenetic protein 2 and pharmacologically suppresses the effect of noggin. Bone 2008 43(2):371-6 PubMed ID: 18515207 DOI: 10.1016/j.bone.2008.03.029

7807 Shibata Y, He LH, Toda Y, Kataoka Y, Fujisawa N, Miyazaki T, Swain MV. Micromechanical evaluation of mineralized multilayers. J Biomech 2008 41(16):3414-8 PubMed ID: 18995855 DOI: 10.1016/j.jbiomech.2008.09.018

7818 Chia-Hua Yang, Ying Li, Wei-Jen Chang, Duen-Jeng Wang, Sheng-Yang Lee, Yoshimitsu Abiko Reduction of Early Growth Response-1 Gene Expression in Osteoblasts by Hydrogen Peroxide Journal of Hard Tissue Biology 2008 17:31-34 DOI: 10.2485/jhtb.17.31

7824 Yasuda Y, Koike T, Kawamorita T, Saito T. Adiponectin induces dentin sialophosphoprotein in rat dental pulp cells: an in vitro study. J Endod 2008 34(6):679-83 PubMed ID: 18498888 DOI: 10.1016/j.joen.2008.02.038

7825 Yanyin Yang Durgadas Bolikal Matthew L. Becker Joachim Kohn Diana N. Zeiger Carl G. Simon Jr Combinatorial polymer scaffold libraries for screening cell‐biomaterial interactions in 3D Adv. Mater 2008 20:2037–2043 DOI: 10.1002/adma.200702088

7826 Wei YY, Chen YJ, Hsiao YC, Huang YC, Lai TH, Tang CH. Osteoblasts-derived TGF-beta1 enhance motility and integrin upregulation through Akt, ERK, and NF-kappaB-dependent pathway in human breast cancer cells. Mol Carcinog 2008 47(7):526-37 PubMed ID: 18161870 DOI: 10.1002/mc.20411

7830 Hidetaka Ishino, Yutaka Kawahito, Yasunori Tsubouchi, Masataka Kohno, Makoto Wada, Aihiro Yamamoto, Masahide Hamaguchi, Masatoshi Kadoya, Daisaku Tokunaga, Tatsuya Hojo, Masahide Matsuyama, Rikio Yoshimura, Toshikazu Yoshikawa Feedback Control of the Arachidonate Cascade in Osteoblastic Cells by 15-deoxy-Δ12, 14-Prostaglandin J2 Journal of Clinical Biochemistry and Nutrition 2008 42:64-69 PubMed ID: 18231633 DOI: 10.3164/jcbn.2008011

7831 Ko EK, Jeong SI, Lee JH, Shin H. Improvement of differentiation and mineralization of pre-osteoblasts on composite nanofibers of poly(lactic acid) and nanosized bovine bone powder. Macromol Biosci 2008 8(12):1098-107 PubMed ID: 18781556 DOI: 10.1002/mabi.200800089

7832 Ishikuro M, Sakamoto K, Kayamori K, Akashi T, Kanda H, Izumo T, Yamaguchi A. Significance of the fibrous stroma in bone invasion by human gingival squamous cell carcinomas. Bone 2008 43(3):621-7 PubMed ID: 18585993 DOI: 10.1016/j.bone.2008.05.014

7839 Ryosuke OHNO, Naoko NAKAMURA, Chiaki HIWA, Kumiko YOKOTA, Yoshikazu NAKAI A310 Relationship between internal structural size of the Scaffold and bone tissue regeneration The Proceedings of the JSME Conference on Frontiers in Bioengineering 2008 19:99-100 DOI: 10.1299/jsmebiofro.2008.19.99

7844 Nakasaki M, Yoshioka K, Miyamoto Y, Sasaki T, Yoshikawa H, Itoh K. IGF-I secreted by osteoblasts acts as a potent chemotactic factor for osteoblasts. Bone 2008 43(5):869-79 PubMed ID: 18718566 DOI: 10.1016/j.bone.2008.07.241

7863 Maehira F1, Iinuma Y, Eguchi Y, Miyagi I, Teruya S. Effects of soluble silicon compound and deep-sea water on biochemical and mechanical properties of bone and the related gene expression in mice. J Bone Miner Metab 2008 26(5):446-55 PubMed ID: 18758902 DOI: 10.1007/s00774-007-0845-x

7864 Tanimoto Y, Shibata Y, Kataoka Y, Miyazaki T, Nishiyama N. Osteoblast-like cell proliferation on tape-cast and sintered tricalcium phosphate sheets. Acta Biomater 2008 4(2):397-402 PubMed ID: 18054299 DOI: 10.1016/j.actbio.2007.10.001

7865 Roelofsen T, Akkers R, Beumer W, Apotheker M, Steeghs I, van de Ven J, Gelderblom C, Garritsen A, Dechering K. Sphingosine-1-phosphate acts as a developmental stage specific inhibitor of platelet-derived growth factor-induced chemotaxis of osteoblasts. J Cell Biochem 2008 105(4):1128-38 PubMed ID: 18819098 DOI: 10.1002/jcb.21915

7877 Tamiya H, Ikeda T, Jeong JH, Saito T, Yano F, Jung YK, Ohba S, Kawaguchi H, Chung UI, Choi JY. Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator. Gene 2008 416(1-2):53-60 PubMed ID: 18442887 DOI: 10.1016/j.gene.2008.03.003

7878 Adachi T, Sato K, Higashi N, Tomita Y, Hojo M. Simultaneous observation of calcium signaling response and membrane deformation due to localized mechanical stimulus in single osteoblast-like cells. J Mech Behav Biomed Mater 2008 1(1):43-50 PubMed ID: 19627770 DOI: 10.1016/j.jmbbm.2007.06.003

7879 Oki Y, Watanabe S, Endo T, Kano K. Mature adipocyte-derived dedifferentiated fat cells can trans-differentiate into osteoblasts in vitro and in vivo only by all-trans retinoic acid. Cell Struct Funct 2008 33(2):211-22 PubMed ID: 19088398 DOI: 10.1247/csf.08038

7881 M. Casolaro, Y. Ito, T. Ishii, S. Bottari, F. Samperi, R. Mendichi Stimuli-responsive poly(ampholyte)s containing L-histidine residues: synthesis and protonation thermodynamics of methacrylic polymers in the free and in the cross-linked gel forms eXPRESS Polymer Letters 2008 2:165–183 DOI: 10.3144/expresspolymlett.2008.22

7897 Isao HIRATA, Masayuki OKAZAKI Higher Concentrations of Fluoride Ions Dramatically Inhibit the Survival of Osteoblasts Journal of Oral Tissue Engineering 2008 6:3-8 DOI: 10.11223/jarde.6.3

7904 Hosaka H, Nagata A, Yoshida T, Shibata T, Nagao T, Tanaka T, Saito Y, Tatsuno I. Pancreatic polypeptide is secreted from and controls differentiation through its specific receptors in osteoblastic MC3T3-E1 cells. Peptides 2008 29(8):1390-5 PubMed ID: 18440094 DOI: 10.1016/j.peptides.2008.03.015

7919 Nomura-Furuwatari C, Wakitani S, Hashimoto Y, Imai Y, Ohta Y, Nakagawa K, Nakao Y, Takayama K, Manaka T, Takaoka K. Expression profiles of phosphodiesterase 4D splicing variants in osteoblastic cells. J Bone Miner Metab 2008 26(2):152-8 PubMed ID: 18301971 DOI: 10.1007/s00774-007-0803-7

7939 Mori K, Blanchard F, Charrier C, Battaglia S, Ando K, Duplomb L, Shultz LD, Redini F, Heymann D. Conditioned media from mouse osteosarcoma cells promote MC3T3-E1 cell proliferation using JAKs and PI3-K/Akt signal crosstalk. Cancer Sci 2008 99(11):2170-6 PubMed ID: 18957057 DOI: 10.1111/j.1349-7006.2008.00919.x

7922 Alvarez K, Hyun SK, Fujimoto S, Nakajima H. In vitro corrosion resistance of Lotus-type porous Ni-free stainless steels. J Mater Sci Mater Med 2008 19(11):3385-97 PubMed ID: 18545945 DOI: 10.1007/s10856-008-3458-6

15462 Toshihiko Shiraishi, Takafumi Onishi, Shin Morishita, Ryohei Takeuchi Measurement of Dynamic Viscoelasticity of an Osteoblast Under Adhesive Condition Using a Piezoelectric Vibrator Biomedical and Biotechnology Engineering 2008 DOI: 10.1115/imece2008-67235

16613 Su-Jung Park Chemical Observation of Anodic TiO2 for Biomaterial Application Metals and Materials International 2008 14:449-455

17403 Toda Y, Shibata Y, Kataoka Y, Kawawa T, Miyazaki T. Interfacial assembly of bioinspired nanostructures mediated by supersensitive crystals J Biomed Mater Res A 2008 84(4):869-74 PubMed ID: 17635033 DOI: 10.1002/jbm.a.31488

17404 Hojo H, Igawa K, Ohba S, Yano F, Nakajima K, Komiyama Y, Ikeda T, Lichtler AC, Woo JT, Yonezawa T, Takato T, Chung UI. Development of high-throughput screening system for osteogenic drugs using a cell-based sensor Biochem Biophys Res Commun 2008 376(2):375-9 PubMed ID: 18789892 DOI: 10.1016/j.bbrc.2008.08.167

8785 Yen PH, Kiem PV, Nhiem NX, Tung NH, Quang TH, Minh CV, Kim JW, Choi EM, Kim YH. A new monoterpene glycoside from the roots of Paeonia lactiflora increases the differentiation of osteoblastic MC3T3-E1 cells. Arch. Pharm. Res. 2007 30:1179-85 PubMed ID: 18038896 DOI: 10.1007/BF02980258

8803 Kawai S, Yamauchi M, Wakisaka S, Ooshima T, Amano A. Zinc-finger transcription factor odd-skipped related 2 is one of the regulators in osteoblast proliferation and bone formation. J. Bone Miner. Res. 2007 22:1362-72 PubMed ID: 17547533 DOI: 10.1359/jbmr.070602

8806 Wang J, Shang F, Jiang R, Liu L, Wang S, Hou J, Huan M, Mei Q. Nitric oxide-donating genistein prodrug: design, synthesis, and bioactivity on MC3T3-E1 cells. J. Pharmacol. Sci. 2007 104:82-9 PubMed ID: 17510526 DOI: 10.1254/jphs.fp0061549

8839 J.?E. Raynor, T.?A. Petrie, A.?J. Garcia, D.?M. Collard Controlling Cell Adhesion to Titanium: Functionalization of Poly[oligo(ethylene glycol)methacrylate] Brushes with Cell-Adhesive Peptides Adv Mater 2007 19:1724-1728 DOI: 10.1002/adma.200602129

8840 Jiepin Wang, Fujun Shang, Li Liu, Siwang wang, Jianbo Wang, Qibing Mei In vivo and in vitro activity of genistein in osteoporosis Indian J Pharmacol 2007 39:103-106

8841 Ramakrishnaiah Siddappa, Winfried Mulder, Ilse Steeghs, Christine van de Klundert, Jun Liu, Roel Arends, Clemens van Blitterswijk and Jan de Boer PKA signaling inhibits osteogenic differentiation and bone formation in rodent models Cellular and Molecular Prerequisites for Bone Tissue Engineering 2007 73-90

18907 Tetsuo Shikata, Toshihiko Shiraishi, Kumiko Tanaka, Shin Morishita, Ryohei Takeuchi Effects of Amplitude and Frequency of Vibration Stimulation on Cultured Osteoblasts Biennial Conference on Mechanical Vibration and Noise, Parts A, B, and C 2007 Volume 1: 21st DOI: 10.1115/detc2007-34949

19199 Kelly P. Alvarez, S.K. Hyun, H. Nakajima, S. Fujimoto Electrochemical Behavior of High Nitrogen Ni-Free Austenitic Stainless Steels in L929 Cells and Cell Culture Medium ECS Transactions 2007 6:13-19 DOI: 10.1149/1.2812436

6502 Wako M, Haro H, Ando T, Hatsushika K, Ohba T, Iwabuchi S, Nakao A, Hamada Y. Novel function of TWEAK in inducing intervertebral disc degeneration. J Orthop Res 2007 25(11):1438-46 PubMed ID: 17568422 DOI: 10.1002/jor.20445

7055 Tani-Ishii N, Hamada N, Watanabe K, Tujimoto Y, Teranaka T, Umemoto T. Expression of bone extracellular matrix proteins on osteoblast cells in the presence of mineral trioxide. J Endod 2007 33(7):836-9 PubMed ID: 17804324 DOI: 10.1016/j.joen.2007.02.003

7057 Arai M, Shibata Y, Pugdee K, Abiko Y, Ogata Y. Effects of reactive oxygen species (ROS) on antioxidant system and osteoblastic differentiation in MC3T3-E1 cells. IUBMB Life 2007 59(1):27-33 PubMed ID: 17365177 DOI: 10.1080/15216540601156188

7059 Verlinden L, Vanden Bempt I, Eelen G, Drijkoningen M, Verlinden I, Marchal K, De Wolf-Peeters C, Christiaens MR, Michiels L, Bouillon R, Verstuyf A. The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor /progesterone receptor /HER-2 breast carcinomas. Cancer Res 2007 67(14):6574-81 PubMed ID: 17638866 DOI: 10.1158/0008-5472.CAN-06-3545

7061 Lee DH, Lim BS, Lee YK, Yang HC. Mechanisms of root canal sealers cytotoxicity on osteoblastic cell line MC3T3-E1. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 104(5):717-21 PubMed ID: 17706441 DOI: 10.1016/j.tripleo.2007.05.018

7064 Choi EM. Modulatory effects of luteolin on osteoblastic function and inflammatory mediators in osteoblastic MC3T3-E1 cells. Cell Biol Int 2007 31(9):870-7 PubMed ID: 17368935 DOI: 10.1016/j.cellbi.2007.01.038

7068 Verlinden L, Eelen G, Van Hellemont R, Engelen K, Beullens I, Van Camp M, Marchal K, Mathieu C, Bouillon R, Verstuyf A. 1alpha,25-Dihydroxyvitamin D3-induced down-regulation of the checkpoint proteins, Chk1 and Claspin, is mediated by the pocket proteins p107 and p130. J Steroid Biochem Mol Biol 2007 103(3-5):411-5 PubMed ID: 17251008 DOI: 10.1016/j.jsbmb.2006.12.080

7070 Kanazawa I, Yamaguchi T, Yano S, Yamauchi M, Yamamoto M, Sugimoto T. Adiponectin and AMP kinase activator stimulate proliferation, differentiation, and mineralization of osteoblastic MC3T3-E1 cells. BMC Cell Biol 2007 8:51 PubMed ID: 18047638 DOI: 10.1186/1471-2121-8-51

7071 Choi EM. Apigenin increases osteoblastic differentiation and inhibits tumor necrosis factor-alpha-induced production of interleukin-6 and nitric oxide in osteoblastic MC3T3-E1 cells. Pharmazie 2007 62(3):216-20 PubMed ID: 17416199

7073 Tsubaki M, Kato C, Manno M, Ogaki M, Satou T, Itoh T, Kusunoki T, Tanimori Y, Fujiwara K, Matsuoka H, Nishida S. Macrophage inflammatory protein-1alpha (MIP-1alpha) enhances a receptor activator of nuclear factor kappaB ligand (RANKL) expression in mouse bone marrow stromal cells and osteoblasts through MAPK and PI3K/Akt pathways. Mol Cell Biochem 2007 304(1-2):53-60 PubMed ID: 17549607 DOI: 10.1007/s11010-007-9485-7

7076 Murshid SA, Kamioka H, Ishihara Y, Ando R, Sugawara Y, Takano-Yamamoto T. Actin and microtubule cytoskeletons of the processes of 3D-cultured MC3T3-E1 cells and osteocytes. J Bone Miner Metab 2007 25(3):151-8 PubMed ID: 17447112 DOI: 10.1007/s00774-006-0745-5

7081 Hata K, Ikebe K, Wada M, Nokubi T. Osteoblast response to titanium regulates transcriptional activity of Runx2 through MAPK pathway. J Biomed Mater Res A 2007 81(2):446-52 PubMed ID: 17117476 DOI: 10.1002/jbm.a.31086

7084 Miyazono A, Yamada A, Morimura N, Takami M, Suzuki D, Kobayashi M, Tezuka K, Yamamoto M, Kamijo R. TGF-beta suppresses POEM expression through ERK1/2 and JNK in osteoblasts. FEBS Lett 2007 581(27):5321-6 PubMed ID: 17977532 DOI: 10.1016/j.febslet.2007.10.021

7098 Tang CH, Lu DY, Tan TW, Fu WM, Yang RS. Ultrasound induces hypoxia-inducible factor-1 activation and inducible nitric-oxide synthase expression through the integrin/integrin-linked kinase/Akt/mammalian target of rapamycin pathway in osteoblasts. J Biol Chem 2007 282(35):25406-15 PubMed ID: 17588951 DOI: 10.1074/jbc.M701001200

7099 Huang Y, Wang Y, Ning C, Nan K, Han Y. Hydroxyapatite coatings produced on commercially pure titanium by micro-arc oxidation. Biomed Mater 2007 2(3):196-201 PubMed ID: 18458472 DOI: 10.1088/1748-6041/2/3/005

7110 Sawada N, Taketani Y, Amizuka N, Ichikawa M, Ogawa C, Nomoto K, Nashiki K, Sato T, Arai H, Isshiki M, Segawa H, Yamamoto H, Miyamoto K, Takeda E. Caveolin-1 in extracellular matrix vesicles secreted from osteoblasts. Bone 2007 41(1):52-8 PubMed ID: 17448744 DOI: 10.1016/j.bone.2007.02.030

7114 Kono SJ, Oshima Y, Hoshi K, Bonewald LF, Oda H, Nakamura K, Kawaguchi H, Tanaka S. Erk pathways negatively regulate matrix mineralization. Bone 2007 40(1):68-74 PubMed ID: 16978937 DOI: 10.1016/j.bone.2006.07.024

7129 Wachiralarpphaithoon C, Iwasaki Y, Akiyoshi K. Enzyme-degradable phosphorylcholine porous hydrogels cross-linked with polyphosphoesters for cell matrices. Biomaterials 2007 28(6):984-93 PubMed ID: 17107708 DOI: 10.1016/j.biomaterials.2006.10.024

7169 Simon CG Jr, Stephens JS, Dorsey SM, Becker ML. Fabrication of combinatorial polymer scaffold libraries. Rev Sci Instrum 2007 78(7):072207 PubMed ID: 17672738 DOI: 10.1063/1.2755761

7170 Christakos S, Dhawan P, Peng X, Obukhov AG, Nowycky MC, Benn BS, Zhong Y, Liu Y, Shen Q. New insights into the function and regulation of vitamin D target proteins. J Steroid Biochem Mol Biol 2007 103(3-5):405-10 PubMed ID: 17257825 DOI: 10.1016/j.jsbmb.2006.12.079

7171 Bandow K, Nishikawa Y, Ohnishi T, Kakimoto K, Soejima K, Iwabuchi S, Kuroe K, Matsuguchi T. Low-intensity pulsed ultrasound (LIPUS) induces RANKL, MCP-1, and MIP-1beta expression in osteoblasts through the angiotensin II type 1 receptor. J Cell Physiol 2007 ;211(2):392-8 PubMed ID: 17167786 DOI: 10.1002/jcp.20944

7172 Yu LY, Pei Y, Xia WB, Xing XP, Meng XW, Zhou XY. Effect of fibroblast growth factor 9 on Runx2 gene promoter activity in MC3T3-E1 and C2C12 cells. Chin Med J (Engl). 2007 120(6):491-5 PubMed ID: 17439743

7176 Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu Investigation on the Biomimetic Scaffold for Bone Tissue Engineering Based on Bioglass-Collagen-Hyaluronic Acid-Phosphatidylserine Key Engineering Materials 2007 330-332 DOI: 10.4028/www.scientific.net/KEM.330-332.939

7177 Kino R, Ikoma T, Yunoki S, Nagai N, Tanaka J, Asakura T, Munekata M. Preparation and characterization of multilayered hydroxyapatite/silk fibroin film. J Biosci Bioeng 2007 103(6):514-20 PubMed ID: 17630122 DOI: 10.1263/jbb.103.514

7197 Uno K, Takarada T, Hinoi E, Yoneda Y. Glutamate is a determinant of cellular proliferation through modulation of nuclear factor E2 p45-related factor-2 expression in osteoblastic MC3T3-E1 cells. J Cell Physiol 2007 213(1):105-14 PubMed ID: 17443688 DOI: 10.1002/jcp.21095

7198 Irwin R, LaPres JJ, Kinser S, McCabe LR. Prolyl-hydroxylase inhibition and HIF activation in osteoblasts promotes an adipocytic phenotype. J Cell Biochem 2007 100(3):762-72 PubMed ID: 17031858 DOI: 10.1002/jcb.21083

7199 Maki M, Miyazaki H, Nakajima K, Yamane J, Niisato N, Morihara T, Kubo T, Marunaka Y. Chloride-dependent acceleration of cell cycle via modulation of Rb and cdc2 in osteoblastic cells. Biochem Biophys Res Commun 2007 361(4):1038-43 PubMed ID: 17679140 DOI: 10.1016/j.bbrc.2007.07.131

7214 Kawate H, Wu Y, Ohnaka K, Takayanagi R. Mutual transactivational repression of Runx2 and the androgen receptor by an impairment of their normal compartmentalization. J Steroid Biochem Mol Biol 2007 105(1-5):46-56 PubMed ID: 17627815 DOI: 10.1016/j.jsbmb.2006.11.020

7227 Ohba S, Nakajima K, Komiyama Y, Kugimiya F, Igawa K, Itaka K, Moro T, Nakamura K, Kawaguchi H, Takato T, Chung UI. A novel osteogenic helioxanthin-derivative acts in a BMP-dependent manner. Biochem Biophys Res Commun 2007 357(4):854-60 PubMed ID: 17451649 DOI: 10.1016/j.bbrc.2007.03.173

7232 Ishii T, Wada A, Tsuzuki S, Casolaro M, Ito Y. Copolymers including L-histidine and hydrophobic moiety for preparation of nonbiofouling surface. Biomacromolecules 2007 8(11):3340-4 PubMed ID: 17915936 DOI: 10.1021/bm070420h

7234 Kosaku KURATA, Hiroyasu TANIGUCHI, Takanobu FUKUNAGA, Junpei MATSUDA, Hidehiko HIGAKI Development of a Compact Microbubble Generator and Its Usefulness for Three-Dimensional Osteoblastic Cell Culture Journal of Biomechanical Science and Engineering 2007 4:166-177 DOI: 10.1299/jbse.2.166

7236 Zhu L, Ye X, Tang G, Zhao N, Gong Y, Zhao Y, Zhao J, Zhang X. Biomimetic coating of compound titania and hydroxyapatite on titanium. J Biomed Mater Res A 2007 83(4):1165-75 PubMed ID: 17595022 DOI: 10.1002/jbm.a.31401

7240 Mori K, Le Goff B, Charrier C, Battaglia S, Heymann D, Rédini F. DU145 human prostate cancer cells express functional receptor activator of NFkappaB: new insights in the prostate cancer bone metastasis process. Bone 2007 40(4):981-90 PubMed ID: 17196895 DOI: 10.1016/j.bone.2006.11.006

7245 Sawajiri M1, Takinami S, Uchida T, Nomura Y, Mizoe J, Banik S, Tanimoto K. Expression of MMP-13 in osteoblast cells and rat tibia after exposure to gamma rays or accelerated carbon ions. Phys Med 2007 23(2):73-9 PubMed ID: 17568546 DOI: 10.1016/j.ejmp.2007.03.005

7246 Maruyama Z, Yoshida CA, Furuichi T, Amizuka N, Ito M, Fukuyama R, Miyazaki T, Kitaura H, Nakamura K, Fujita T, Kanatani N, Moriishi T, Yamana K, Liu W, Kawaguchi H, Nakamura K, Komori T. Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency. Dev Dyn 2007 236(7):1876-90 PubMed ID: 17497678 DOI: 10.1002/dvdy.21187

7267 Chau Van Minha , Nguyen Xuan Cuonga , Tran Anh Tuana , Eun Mi Choib , Young Ho Kimb and Phan Van Kiema, A New 9,11-Secosterol from the Vietnamese Sea Soft Coral, Sarcophyton Mililatensis, Increases the Function of Osteoblastic MC3T3-E1 Cells Natural Product Communications 2007 2(11) DOI: 10.1177/1934578X0700201109

7268 Xu HH, Carey LE, Simon CG Jr, Takagi S, Chow LC. Premixed calcium phosphate cements: synthesis, physical properties, and cell cytotoxicity. Dent Mater 2007 23(4):433-41 PubMed ID: 16678895 DOI: 10.1016/j.dental.2006.02.014

7269 Takarada T, Hinoi E, Kambe Y, Sahara K, Kurokawa S, Takahata Y, Yoneda Y. Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative cytotoxicity of ascorbic acid. Eur J Pharmacol 2007 575(1-3):1-11 PubMed ID: 17698058 DOI: 10.1016/j.ejphar.2007.07.041

7272 Xu HH, Carey LE, Simon CG Jr. Premixed macroporous calcium phosphate cement scaffold. J Mater Sci Mater Med 2007 18(7):1345-53 PubMed ID: 17277972 DOI: 10.1007/s10856-007-0146-x

7276 Zapata P, Su J, García AJ, Meredith JC. Quantitative high-throughput screening of osteoblast attachment, spreading, and proliferation on demixed polymer blend micropatterns. Biomacromolecules 2007 8(6):1907-17 PubMed ID: 17506518 DOI: 10.1021/bm061134t

7301 Tadashi Shinohara, Tomoyuki Saito, Daisuke Saito, Makoto Kotani, and Masaaki Aoki Permanent magnets circuit for collagen orientation phys stat.sol (c) 2007 4:4333–4336 DOI: 10.1002/pssc.200777290

7335 Sato K, Adachi T, Ueda D, Hojo M, Tomita Y. Measurement of local strain on cell membrane at initiation point of calcium signaling response to applied mechanical stimulus in osteoblastic cells. J Biomech 2007 40(6):1246-55 PubMed ID: 16887125 DOI: 10.1016/j.jbiomech.2006.05.028

7336 Miho NAKAMURA, Natalie OHASHI, Akiko NAGAI, Yasutaka SEKIJIMA, Yumi TANAKA, Satoshi NAKAMURA, Kimihiro YAMASHITA Modulation of Osteoblast-Like Cell Behavior Cultured on Hydroxyapatite by Thrombin Journal of the Ceramic Society of Japan 2007 115 ;205-209 DOI: 10.2109/jcersj.115.205

7337 T. ADACHI, K. SATO, M. HOJO and Y. TOMITA CYTOSKELETAL REASSEMBLING AND CALCIUM SIGNALING RESPONSES TO MECHANICAL PERTURBATION IN OSTEOBLASTIC CELLS Biomechanics at Micro- and Nanoscale Levels 2007 49-59 DOI: 10.1142/9789812771322_0005

7343 Mello A, Hong Z, Rossi AM, Luan L, Farina M, Querido W, Eon J, Terra J, Balasundaram G, Webster T, Feinerman A, Ellis DE, Ketterson JB, Ferreira CL. Osteoblast proliferation on hydroxyapatite thin coatings produced by right angle magnetron sputtering. Biomed Mater 2007 2(2):67-77 PubMed ID: 18458438 DOI: 10.1088/1748-6041/2/2/003

7349 Ito M, Haito S, Furumoto M, Uehata Y, Sakurai A, Segawa H, Tatsumi S, Kuwahata M, Miyamoto K. Unique uptake and efflux systems of inorganic phosphate in osteoclast-like cells. Am J Physiol Cell Physiol 2007 292(1):C526-34 PubMed ID: 16971494 DOI: 10.1152/ajpcell.00357.2006

7352 Huang MS, Morony S, Lu J, Zhang Z, Bezouglaia O, Tseng W, Tetradis S, Demer LL, Tintut Y. Atherogenic phospholipids attenuate osteogenic signaling by BMP-2 and parathyroid hormone in osteoblasts. J Biol Chem 2007 282(29):21237-43 PubMed ID: 17522049 DOI: 10.1074/jbc.M701341200

7356 Hirao M, Hashimoto J, Yamasaki N, Ando W, Tsuboi H, Myoui A, Yoshikawa H. Oxygen tension is an important mediator of the transformation of osteoblasts to osteocytes. J Bone Miner Metab 2007 25(5):266-76 PubMed ID: 17704991 DOI: 10.1007/s00774-007-0765-9

7363 Hirata I, Nomura Y, Ito M, Shimazu A, Okazaki M. Acceleration of bone formation with BMP2 in frame-reinforced carbonate apatite-collagen sponge scaffolds. J Artif Organs 2007 10(4):212-7 PubMed ID: 18071850 DOI: 10.1007/s10047-007-0391-2

7388 Katsuyama H, Saijoh K, Otsuki T, Tomita M, Fukunaga M, Sunami S. Menaquinone-7 regulates gene expression in osteoblastic MC3T3E1 cells. Int J Mol Med 2007 19(2):279-84 PubMed ID: 17203202

7389 Sanuki R, Mitsui N, Suzuki N, Koyama Y, Yamaguchi A, Isokawa K, Shimizu N, Maeno M. Effect of compressive force on the production of prostaglandin E(2) and its receptors in osteoblastic Saos-2 cells. Connect Tissue Res 2007 48(5):246-53 PubMed ID: 17882700 DOI: 10.1080/03008200701541775

7646 Takao Saito, Hikoshiro Hayashi, Tetsuya Kameyama, Katsuya Kato Cellular Responses of MC3T3-E1 Mouse Osteoblast-Like Cells to Rough Surfaced Substrates Key Engineering Materials 2007 361-363:1071-1074 DOI: 10.4028/www.scientific.net/KEM.361-363.1071

7733 Taro Takemura, Toshiyuki Ikoma, Nobutaka Hanagata Effect of Acid Treated Hydroxyapatite on Osteoblast Maturation Key Engineering Materials 2007 361-363:1029-1032 DOI: 10.4028/www.scientific.net/KEM.361-363.1029

7856 Miho Nakamura, Akiko Nagai, Natalie Ohashi, Yumi Tanaka, Yasutaka Sekijima, Satoshi Nakamura, Kimihiro Yamashita Regulation of Osteoblast-Like Cell Behaviors on Hydroxyapatite by Electrical Polarization Key Engineering Materials 2007 361-363:1055-1058 DOI: 10.4028/www.scientific.net/KEM.361-363.1055

7867 Zhen Hong, Alexandre Mello, Tomohiko Yoshida, Lan Luan, Paula H. Stern, Antonella M. Rossi, Donald E. Ellis, J.B. Ketterson Increased Osteoblast Proliferation on Hydroxyapatite Thin Coatings Produced by Right Angle Magnetron Sputtering Key Engineering Materials 2007 361-363:215-218 DOI: 10.4028/www.scientific.net/KEM.361-363.215

15174 Fuse Y, Hirata I, Kurihara H, Okazaki M. Cell adhesion and proliferation patterns on mixed self-assembled monolayers carrying various ratios of hydroxyl and methyl groups Dent Mater J 2007 26(6):814-9 PubMed ID: 18203486 DOI: 10.4012/dmj.26.814

15380 Saita Y, Takagi T, Kitahara K, Usui M, Miyazono K, Ezura Y, Nakashima K, Kurosawa H, Ishii S, Noda M. Lack of Schnurri-2 expression associates with reduced bone remodeling and osteopenia J Biol Chem 2007 282(17):12907-1 PubMed ID: 17311925 DOI: 10.1074/jbc.M611203200

14196 Y. Aonuma, T. Adachi, M. Tanaka, M. Hojo, T. Takano-Yamamoto and H. Kamioka 3A1 Cellular & Tissue Engineering & Biomaterials I A1 Cellular & Tissue Engineering & Biomaterials I 2007 2:S165-S170 DOI: 10.1299/jbse.2.S165

14249 Takafumi Onishi, Toshihiko Shiraishi, Shin Morishita, Ryohei Takeuchi Viscoelastic Properties of a Cultured Osteoblast Under Adhesive Condition Biennial Conference on Mechanical Vibration and Noise, Parts A, B, and C 2007 Volume 1: 21st DOI: 10.1115/detc2007-34944

15461 Zhendong Hong, Alexandre Mello, Tomohiko Yoshida, Lan Luan, Paula H. Stern, Alexandre Rossi, Donald E. Ellis, John B. Ketterson Hydroxyapatite Coatings Produced by Right Angle Magnetron Sputtering for Biomedical Applications MRS Proceedings 2007 1008 DOI: 10.1557/proc-1008-t10-04

17400 Tetsuo Shikata, Toshihiko Shiraishi, Kumiko Tanaka, Shin Morishita, Ryohei Takeuchi Effects of Acceleration Amplitude and Frequency of Mechanical Vibration on Osteoblast-Like Cells Biomedical and Biotechnology Engineering 2007 2 DOI: 10.1115/imece2007-41797

17401 Yokoi T, Saito M, Kiyono T, Iseki S, Kosaka K, Nishida E, Tsubakimoto T, Harada H, Eto K, Noguchi T, Teranaka T. Establishment of immortalized dental follicle cells for generating periodontal ligament in vivo Cell Tissue Res 2007 327(2):301-11 PubMed ID: 17013589 DOI: 10.1007/s00441-006-0257-6

17402 Hacchou Y, Uematsu T, Ueda O, Usui Y, Uematsu S, Takahashi M, Uchihashi T, Kawazoe Y, Shiba T, Kurihara S, Yamaoka M, Furusawa K. Inorganic polyphosphate: a possible stimulant of bone formation J Dent Res 2007 86(9):893-7 PubMed ID: 17720862 DOI: 10.1177/154405910708600917

3405 Ozeki K, Aoki H, Fukui Y Dissolution behavior and in vitro evaluation of sputtered hydroxyapatite films subject to a low temperature hydrothermal treatment. J Biomed Mater Res A 2006 76:605-13 PubMed ID: 16278871 DOI: 10.1002/jbm.a.30574

3398 Ouyang, Xinshou, Fujimoto, Minoru, Nakagawa, Reiko, Serada, Satoshi, Tanaka, Toshio, Nomura, Shintaro, Kawase, Ichiro, Kishimoto, Tadamitsu, Naka, Tetsuji SOCS-2 interferes with myotube formation and potentiates osteoblast differentiation through upregulation of JunB in C2C12 cells. J Cell Physiol 2006 207:428-36 PubMed ID: 16419040 DOI: 10.1002/jcp.20579

8879 Hanagata N, Takemura T, Monkawa A, Ikoma T, Tanaka J. Pre-adsorbed type-I collagen structure-dependent changes in osteoblastic phenotype. Biochem. Biophys. Res. Commun. 2006 344:1234-40 PubMed ID: 16647688 DOI: 10.1016/j.bbrc.2006.04.021

6487 Hinoi E, Ueshima T, Hojo H, Iemata M, Takarada T, Yoneda Y. Up-regulation of per mRNA expression by parathyroid hormone through a protein kinase A-CREB-dependent mechanism in chondrocytes. J Biol Chem 2006 281(33):23632-42 PubMed ID: 16777848 DOI: 10.1074/jbc.M512362200

6489 Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A. TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells. Arthritis Res Ther 2006 8(5):R146 PubMed ID: 16945157 DOI: 10.1186/ar2038

6971 Lee DH, Park BJ, Lee MS, Lee JW, Kim JK, Yang HC, Park JC. Chemotactic migration of human mesenchymal stem cells and MC3T3-E1 osteoblast-like cells induced by COS-7 cell line expressing rhBMP-7. Tissue Eng 2006 12(6):1577-86 PubMed ID: 16846353 DOI: 10.1089/ten.2006.12.1577

6972 Lee KH, Choi EM. Rubus coreanus Miq. extract promotes osteoblast differentiation and inhibits bone-resorbing mediators in MC3T3-E1 cells. Am J Chin Med 2006 34(4):643-54. PubMed ID: 16883635 DOI: 10.1142/S0192415X0600417X

6973 Li J, Yun H, Gong Y, Zhao N, Zhang X. Investigation of MC3T3-E1 cell behavior on the surface of GRGDS-coupled chitosan. Biomacromolecules 2006 7(4):1112-23 PubMed ID: 16602728 DOI: 10.1021/bm050913r

6974 Yoshida T, Asanuma M, Grossmann L, Fuse M, Shibata T, Yonekawa T, Tanaka T, Ueno K, Yasuda T, Saito Y, Tatsuno I. Geranylgeranyl-pyrophosphate (GGPP) synthase is down-regulated during differentiation of osteoblastic cell line MC3T3-E1. FEBS Lett 2006 580(22):5203-7 PubMed ID: 16978613 DOI: 10.1016/j.febslet.2006.08.060

6975 Sawajiri M, Nomura Y, Bhawal UK, Nishikiori R, Okazaki M, Mizoe J, Tanimoto K. Different effects of carbon ion and gamma-irradiation on expression of receptor activator of NF-kB ligand in MC3T3-E1 osteoblast cells. Bull Exp Biol Med 2006 142(5):618-24 PubMed ID: 17415477 DOI: 10.1007/s10517-006-0433-4

6976 Nagai N, Anzawa T, Satoh Y, Suzuki T, Tajima K, Munekata M. Activities of MC3T3-E1 cells cultured on gamma-irradiated salmon atelocollagen scaffold. J Biosci Bioeng 2006 101(6):511-4 PubMed ID: 16935254 DOI: 10.1263/jbb.101.511

7051 Lee KH, Choi EM. Stimulatory effects of extract prepared from the bark of Cinnamomum cassia blume on the function of osteoblastic MC3T3-E1 cells. Phytother Res 2006 20(11):952-60 PubMed ID: 16906639 DOI: 10.1002/ptr.1984

6977 Hori M, Sawai H, Tsuji Y, Okamura H, Koyama K. Bone morphogenetic protein-2 counterregulates interleukin-18 mRNA and protein in MC3T3-E1 mouse osteoblastic cells. Connect Tissue Res 2006 47(3):124-32 PubMed ID: 16753805 DOI: 10.1080/03008200600685350

6978 Lee DH, Lim BS, Lee YK, Yang HC. Effects of hydrogen peroxide (H2O2) on alkaline phosphatase activity and matrix mineralization of odontoblast and osteoblast cell lines. Cell Biol Toxicol 2006 22(1):39-46 PubMed ID: 16463018 DOI: 10.1007/s10565-006-0018-z

6979 Kaneko, M. et al Synthesis and characterization of calcium phosphate-AMP layered materials Key Engineering Materials 2006 317-318:769-772 DOI: 10.4028/www.scientific.net/KEM.317-318.769

6980 Tachibana A, Nishikawa Y, Nishino M, Kaneko S, Tanabe T, Yamauchi K. Modified keratin sponge: binding of bone morphogenetic protein-2 and osteoblast differentiation. J Biosci Bioeng 2006 102(5):425-9 PubMed ID: 17189169 DOI: 10.1263/jbb.102.425

6981 Narita Y, Nomura J, Ohta S, Inoh Y, Suzuki KM, Araki Y, Okada S, Matsumoto I, Isohama Y, Abe K, Miyata T, Mishima S. Royal jelly stimulates bone formation: physiologic and nutrigenomic studies with mice and cell lines. Biosci Biotechnol Biochem 2006 70(10):2508-14 PubMed ID: 17031045 DOI: 10.1271/bbb.60240

6982 Petrie TA, Capadona JR, Reyes CD, García AJ. Integrin specificity and enhanced cellular activities associated with surfaces presenting a recombinant fibronectin fragment compared to RGD supports. Biomaterials 2006 27(31):5459-70 PubMed ID: 16846640 DOI: 10.1016/j.biomaterials.2006.06.027

6983 Gao Y, Cao WL, Wang XY, Gong YD, Tian JM, Zhao NM, Zhang XF. Characterization and osteoblast-like cell compatibility of porous scaffolds: bovine hydroxyapatite and novel hydroxyapatite artificial bone. J Mater Sci Mater Med 2006 17(9):815-23 PubMed ID: 16932863 DOI: 10.1007/s10856-006-9840-3

6985 Teraoka F, Nakagawa M, Hara M. Surface modification of poly (L-lactide) by atmospheric pressure plasma treatment and cell response. Dent Mater J 2006 25(3):560-5 PubMed ID: 17076328 DOI: 10.4012/dmj.25.560

6986 Kennedy SB, Washburn NR, Simon CG Jr, Amis EJ. Combinatorial screen of the effect of surface energy on fibronectin-mediated osteoblast adhesion, spreading and proliferation. Biomaterials 2006 27(20):3817-24 PubMed ID: 16563495 DOI: 10.1016/j.biomaterials.2006.02.044

6987 Takafumi ONISHI, Toshihiko SHIRASHI, Shin MORISHITA Mechanical properties of a cultured osteoblast Journal of Advanced Science 2006 18:95-98 DOI: 10.2978/jsas.18.95

6988 Hinoi E, Fujimori S, Wang L, Hojo H, Uno K, Yoneda Y. Nrf2 negatively regulates osteoblast differentiation via interfering with Runx2-dependent transcriptional activation. J Biol Chem 2006 281(26):18015-24 PubMed ID: 16613847 DOI: 10.1074/jbc.M600603200

6989 Yingjun Wang Chunrong Yang Xiaofeng Chen Naru Zhao Development and Characterization of Novel Biomimetic Composite Scaffolds Based on Bioglass‐Collagen‐Hyaluronic Acid‐Phosphatidylserine for Tissue Engineering Applications Macromol Mater Eng 2006 291:254–262 DOI: 10.1002/mame.200500381

6990 Han DW, Park HK, Park YH, Kim TS, Yoon WS, Kim JK, Park JC. Beneficial effects of freezing rate determined by indirect thermophysical calculation on cell viability in cryopreserved tissues. Artif Cells Blood Substit Immobil Biotechnol 2006 34(2):205-21 PubMed ID: 16537175 DOI: 10.1080/10731190600581742

6991 Boilard E, Rouault M, Surrel F, Le Calvez C, Bezzine S, Singer A, Gelb MH, Lambeau G. Secreted phospholipase A2 inhibitors are also potent blockers of binding to the M-type receptor. Biochemistry 2006 45(44):13203-18 PubMed ID: 17073442 DOI: 10.1021/bi061376d

6993 Nakashima A, Tamura M. Regulation of matrix metalloproteinase-13 and tissue inhibitor of matrix metalloproteinase-1 gene expression by WNT3A and bone morphogenetic protein-2 in osteoblastic differentiation. Front Biosci 2006 11:1667-78 PubMed ID: 16368545 DOI: 10.2741/1912

6994 Hosaka M, Shibata Y, Miyazaki T. Preliminary beta-tricalcium phosphate coating prepared by discharging in a modified body fluid enhances collagen immobilization onto titanium. J Biomed Mater Res B Appl Biomater 2006 78(2):237-42 PubMed ID: 16362961 DOI: 10.1002/jbm.b.30478

6995 M. Iwasakaa and T. Kurakane Magnetic cell manipulation utilizing magnetic particles and diamagnetic collagen fibers Journal of Applied Physics 2006 99: 08R90 DOI: 10.1063/1.2175957

6996 Yokota R, Hayashi H, Hirata I, Miake Y, Yanagisawa T, Okazaki M. Detailed consideration of physicochemical properties of CO3apatites as biomaterials in relation to carbonate content using ICP, X-ray diffraction, FT-IR, SEM, and HR-TEM. Dent Mater J 2006 25(3):597-603 PubMed ID: 17076333 DOI: 10.4012/dmj.25.597

6997 Sugama R, Koike T, Imai Y, Nomura-Furuwatari C, Takaoka K. Bone morphogenetic protein activities are enhanced by 3',5'-cyclic adenosine monophosphate through suppression of Smad6 expression in osteoprogenitor cells. Bone 2006 38(2):206-14 PubMed ID: 16203197 DOI: 10.1016/j.bone.2005.08.006

6998 Kawai S, Kato T, Sato M, Amano A. Odd-skipped related 2 gene transcription is regulated by CCAAT enhancer-binding protein delta in mesenchymal C3H10T1/2 cells. Genes Cells 2006 11(2):163-75 PubMed ID: 16436053 DOI: 10.1111/j.1365-2443.2006.00929.x

6999 Hajime SHINOHARA, Hikaru TAKEI, Daisuke SAITO, Makoto KOTANI, Shogo UENO, Atsushi NAKAHIRA Fundamental Study on Bone Formation Using Collagen Orientation Induced by Magnetic Fields Journal of the Ceramic Society of Japan 2006 114:131-134 DOI: 10.2109/jcersj.114.131

7007 Katsuya SATO, Taiji ADACHI, Yasuhito SHIRAI, Naoaki SAITO, Yoshihiro TOMITA Local Disassembly of Actin Stress Fibers Induced by Selected Release of Intracellular Tension in Osteoblastic Cell Journal of Biomechanical Science and Engineering 2006 1:204-214 DOI: 10.1299/jbse.1.204

15421 Hinoi E, Takarada T, Tsuchihashi Y, Fujimori S, Moriguchi N, Wang L, Uno K, Yoneda Y. A molecular mechanism of pyruvate protection against cytotoxicity of reactive oxygen species in osteoblasts Mol Pharmacol5 2006 70(3):925-3 PubMed ID: 16766717 DOI: 10.1124/mol.106.024398

15422 Casolaro M, Casolaro I, Spreafico A, Capperucci C, Frediani B, Marcolongo R, Margiotta N, Ostuni R, Mendichi R, Samperi F, Ishii T, Ito Y. Novel therapeutic agents for bone resorption. Part 1. Synthesis and protonation thermodynamics of poly(amido-amine)s containing bis-phosphonate residues Biomacromolecules 2006 7(12):3417-27 PubMed ID: 17154470 DOI: 10.1021/bm0607630

15423 T. ADACHI, K. SATO THRESHOLD FIBER STRAIN THAT INDUCES REORGANIZATION OF CYTOSKELETAL ACTIN STRUCTURE IN OSTEOBLASTIC CELLS Biomechanics at Micro- and Nanoscale Levels 2006 51-61 DOI: 10.1142/9789812773838_0005

15424 M. Okazaki, Y. Tieliewuhan, I. Hirata Osteoblast Behavior at the Surface of CO3Ap-Collagen Sponges Key Engineering Materials 2006 989-992 DOI: 10.4028/www.scientific.net/kem.309-311.989

5572 Tang CH, Yang RS, Huang TH, Lu DY, Chuang WJ, Huang TF, Fu WM. Ultrasound stimulates cyclooxygenase-2 expression and increases bone formation through integrin, focal adhesion kinase, phosphatidylinositol 3-kinase, and Akt pathway in osteoblasts Mol Pharmacol 2006 69(6):2047-57 PubMed ID: 16540596 DOI: 10.1124/mol.105.022160

3348 Motokawa M, Kaku M, Tohma Y, Kawata T, Fujita T, Kohno S, Tsutsui K, Ohtani J, Tenjo K, Shigekawa M, Kamada H, Tanne K Effects of cyclic tensile forces on the expression of vascular endothelial growth factor (VEGF) and macrophage-colony-stimulating factor (M-CSF) in murine osteoblastic MC3T3-E1 cells. J Dent Res 2005 84:422-7 PubMed ID: 15840777 DOI: 10.1177/154405910508400505

2897 Kim SW, Her SJ, Kim SY, Shin CS Ectopic overexpression of adipogenic transcription factors induces transdifferentiation of MC3T3-E1 osteoblasts. Biochem Biophys Res Commun 2005 327:811-9 PubMed ID: 15649418 DOI: 10.1016/j.bbrc.2004.12.076

2915 Nobta M, Tsukazaki T, Shibata Y, Xin C, Moriishi T, Sakano S, Shindo H, Yamaguchi A Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling. J Biol Chem 2005 280:15842-8 PubMed ID: 15695512 DOI: 10.1074/jbc.M412891200

3018 Sato K, Adachi T, Matsuo M, Tomita Y Quantitative evaluation of threshold fiber strain that induces reorganization of cytoskeletal actin fiber structure in osteoblastic cells. J Biomech 2005 38:1895-901 PubMed ID: 16023478 DOI: 10.1016/j.jbiomech.2004.08.012

3069 Inoue H, Nishimura K, Oka D, Nakai Y, Shiba M, Tokizane T, Arai Y, Nakayama M, Shimizu K, Takaha N, Nonomura N, Okuyama A Prostate cancer mediates osteoclastogenesis through two different pathways. Cancer Lett 2005 223:121-8 PubMed ID: 15890244 DOI: 10.1016/j.canlet.2004.09.053

3084 Kawate H, Wu Y, Ohnaka K, Nawata H, Takayanagi R Tob proteins suppress steroid hormone receptor-mediated transcriptional activation. Mol Cell Endocrinol 2005 230:77-86 PubMed ID: 15664454 DOI: 10.1016/j.mce.2004.10.009

3407 Ito, Mikiko, Sakai, Yuko, Furumoto, Mari, Segawa, Hiroko, Haito, Sakiko, Yamanaka, Setsuko, Nakamura, Rie, Kuwahata, Masashi, Miyamoto, Ken-ichi Vitamin D and phosphate regulate fibroblast growth factor-23 in K-562 cells. Am J Physiol Endocrinol Metab 2005 288:E1101-9 PubMed ID: 15671080 DOI: 10.1152/ajpendo.00502.2004

2930 Keselowsky, Benjamin G, Collard, David M, Garcia, Andres J Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation. Proc Natl Acad Sci U S A 2005 102:5953-7 PubMed ID: 15827122 DOI: 10.1073/pnas.0407356102

8952 Lee KH, Choi EM. Biochanin A stimulates osteoblastic differentiation and inhibits hydrogen peroxide-induced production of inflammatory mediators in MC3T3-E1 cells. Biol. Pharm. Bull. 2005 28:1948-53 PubMed ID: 16204952 DOI: 10.1248/bpb.28.1948

9012 Choi EM. The licorice root derived isoflavan glabridin increases the function of osteoblastic MC3T3-E1 cells. Biochem. Pharmacol. 2005 70:363-8 PubMed ID: 15922308 DOI: 10.1016/j.bcp.2005.04.019

6283 Nagasawa H, Takahashi S, Kobayashi A, Tazawa H, Tashima Y, Sato K. Effect of retinoic acid on murine preosteoblastic MC3T3-E1 cells. J Nutr Sci Vitaminol (Tokyo) 2005 51(5):311-8 PubMed ID: 16392701 DOI: 10.3177/jnsv.51.311

4968 Okada A, Shiomi T, Aoki Y, Fujiwara M. Phenytoin stimulates chondrogenic differentiation in mouse clonal chondrogenic EC cells, ATDC5. J Toxicol Sci 2005 30(3):145-56 PubMed ID: 16141649 DOI: 10.2131/jts.30.145

6824 Kim SW, Her SJ, Park SJ, Kim D, Park KS, Lee HK, Han BH, Kim MS, Shin CS, Kim SY. Ghrelin stimulates proliferation and differentiation and inhibits apoptosis in osteoblastic MC3T3-E1 cells. Bone 2005 37(3):359-69 PubMed ID: 15978880 DOI: 10.1016/j.bone.2005.04.020

6825 Li J, Yun H, Gong Y, Zhao N, Zhang X. Effects of surface modification of poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) on physicochemical properties and on interactions with MC3T3-E1 cells. J Biomed Mater Res A 2005 75(4):985-98 PubMed ID: 16134174 DOI: 10.1002/jbm.a.30504

6826 Xi J, Kong L, Gao Y, Gong Y, Zhao N, Zhang X. Properties of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) films modified with polyvinylpyrrolidone and behavior of MC3T3-E1 osteoblasts cultured on the blended films. J Biomater Sci Polym Ed 2005 16(11):1395-408 PubMed ID: 16370240 DOI: 10.1163/156856205774472344

6827 Takashi M, Tsubaki S, Tsuzuki T, Duarte WR, Yamauchi M, Sato H. Differential gene expression of collagen-binding small leucine-rich proteoglycans and lysyl hydroxylases, during mineralization by MC3T3-E1 cells cultured on titanium implant material. Eur J Oral Sci 2005 113(3):225-31 PubMed ID: 15953247 DOI: 10.1111/j.1600-0722.2005.00208.x

6829 D.H. Lee, Dong Wook Han, B.J. Park, Hyun Sook Baek, K. Takatori, M. Aihara, Kazufumi Tsubaki, Jong Chul Park The Influences of β-Glucan Associated with BMP-7 on MC3T3-E1 Proliferation and Osteogenic Differentiation Key Engineering Materials 2005 288-289:241-244 DOI: 10.4028/www.scientific.net/KEM.288-289.241

6830 Yoko Otsuka-Tanaka, Toshinori Sato, Tomohisa Fujita, Hiroshi Suzuki, Misao Kawara, Yoshimitsu Abiko, Junichi Mega Reduction of Bone Nodule Formation in MC3T3-E1 Cells by Treatment with Hydrogen Peroxide International Journal of Oral-Medical Sciences 2005 4:97-102 DOI: 10.5466/ijoms.4.97

6836 Kikuji Yamashita, Jun Ishibashi, Hiroyoshi Hosokawa, Nanami Ishikawa, Hiroyuki Morimoto, Tomoyasu Ishikawa, Masaru Nagayama, Seiichiro Kitamura Microarray Analysis of Gene Expression in MC3T3-E1 after Specific Far-infrared Radiation Journal of Hard Tissue Biology 2005 14:206-207 DOI: 10.2485/jhtb.14.206

6838 Ku Y, Chung CP, Jang JH. The effect of the surface modification of titanium using a recombinant fragment of fibronectin and vitronectin on cell behavior. Biomaterials 2005 26(25):5153-7 PubMed ID: 15792542 DOI: 10.1016/j.biomaterials.2005.01.060

6839 Keselowsky BG, García AJ. Quantitative methods for analysis of integrin binding and focal adhesion formation on biomaterial surfaces. Biomaterials 2005 26(4):413-8 PubMed ID: 15275815 DOI: 10.1016/j.biomaterials.2004.02.050

6840 Yang RS, Lin WL, Chen YZ, Tang CH, Huang TH, Lu BY, Fu WM. Regulation by ultrasound treatment on the integrin expression and differentiation of osteoblasts. Bone 2005 36(2):276-83 PubMed ID: 15780953 DOI: 10.1016/j.bone.2004.10.009

6841 Kazuo Isama, Toshie Tsuchiya Osteoblast differentiation and apatite formation on gamma-irradiated PLLA sheets Key Engineering Materials 2005 288-289:409-412 DOI: 10.4028/www.scientific.net/KEM.288-289.409

6842 Tachibana A, Kaneko S, Tanabe T, Yamauchi K. Rapid fabrication of keratin-hydroxyapatite hybrid sponges toward osteoblast cultivation and differentiation. Biomaterials 2005 26(3):297-302 PubMed ID: 15262471 DOI: 10.1016/j.biomaterials.2004.02.032

6843 Dong HeeLee, Hyun Sook Baek, Mi Hee Lee, Jong-Chul Parka Production of bone morphogenetic protein-7 using pET expression system Current Applied Physics 2005 5:422-425 DOI: 10.1016/j.cap.2005.01.003

6844 Zhang K, Washburn NR, Simon CG Jr. Cytotoxicity of three-dimensionally ordered macroporous sol-gel bioactive glass (3DOM-BG). Biomaterials 2005 26(22):4532-9 PubMed ID: 15722122 DOI: 10.1016/j.biomaterials.2004.11.030

6845 Kai Zhang, Newell R. Washburn, Joseph M. Antonucci, Carl G. Simon In Vitro Culture of Osteoblasts with Three Dimensionally Ordered Macroporous Sol-Gel Bioactive Glass (3DOM-BG) Particles Key Engineering Materials 2005 284-286:655-658 DOI: 10.4028/www.scientific.net/KEM.284-286.655

6846 Jing Li Yandao Gong Nanming Zhao Xiufang Zhang Preparation of N‐butyl chitosan and study of its physical and biological properties Journal of applied polymer science 2005 98:1016-1024 DOI: 10.1002/app.22212

6847 J. R. Capadona T. A. Petrie K. P. Fears R. A. Latour D. M. Collard A. J. García Surface‐Nucleated Assembly of Fibrillar Extracellular Matrices Adv Mater 2005 17:2604–2608 DOI: 10.1002/adma.200500959

6848 C. G. Simon, Jr, J. M. Antonucci, D. W. Liu, D. Skrtic D. Skrtic In vitro Cytotoxicity of Amorphous Calcium Phosphate Composites Journal of Bioactive and Compatible Polymers 2005 20:279-295 DOI: 10.1177/0883911505051854

6849 Verlinden L, Eelen G, Beullens I, Van Camp M, Van Hummelen P, Engelen K, Van Hellemont R, Marchal K, De Moor B, Foijer F, Te Riele H, Beullens M, Bollen M, Mathieu C, Bouillon R, Verstuyf A. Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3. J Biol Chem 2005 280(45):37319-30 PubMed ID: 16144839 DOI: 10.1074/jbc.M503587200

6850 Shen Q1, Christakos S. The vitamin D receptor, Runx2, and the Notch signaling pathway cooperate in the transcriptional regulation of osteopontin. J Biol Chem 2005 280(49):40589-98 PubMed ID: 16195230 DOI: 10.1074/jbc.M504166200

6851 Susumu Hamajima, Toshinori Sato, Yoko-Otsuka Tanaka, Chia-Hua Yang, Nobuyuki Watanabe, Junichi Mega, Toshiro Sakae, Yoshimitsu Abiko Identification of Reduced Fibronectin 1 Gene Expression in Osteoblasts following Hydrogen Peroxide Treatment using Subtractive Gene Cloning Journal of Hard Tissue Biology 2005 14:32-37 DOI: 10.2485/jhtb.14.32

6852 K. Ozeki, Hideyuki Aoki, Y. Fukui Crystallization of sputtered hydroxyapatite films by hydrothermal technique and its cytotoxicity Key Engineering Materials 2005 284-286:195-198 DOI: 10.4028/www.scientific.net/KEM.284-286.195

6853 Ohta H, Wakitani S, Tensho K, Horiuchi H, Wakabayashi S, Saito N, Nakamura Y, Nozaki K, Imai Y, Takaoka K. The effects of heat on the biological activity of recombinant human bone morphogenetic protein-2. J Bone Miner Metab 2005 23(6):420-5 PubMed ID: 16261447 DOI: 10.1007/s00774-005-0623-6

6854 Simon CG Jr, Eidelman N, Kennedy SB, Sehgal A, Khatri CA, Washburn NR. Combinatorial screening of cell proliferation on poly(L-lactic acid)/poly(D,L-lactic acid) blends. Biomaterials 2005 26(34):6906-15 PubMed ID: 15939467 DOI: 10.1016/j.biomaterials.2005.04.050

6855 Zhang K, Simon CG Jr, Washburn NR, Antonucci JM, Lin-Gibson S. In situ formation of blends by photopolymerization of poly(ethylene glycol) dimethacrylate and polylactide. Biomacromolecules. 2005 6(3):1615-22 PubMed ID: 15877385 DOI: 10.1021/bm0500648

6856 Xu HH1, Simon CG Jr. Fast setting calcium phosphate-chitosan scaffold: mechanical properties and biocompatibility. Biomaterials 2005 26(12):1337-48 PubMed ID: 15482821 DOI: 10.1016/j.biomaterials.2004.04.043

6857 Liu Y, Shen Q, Malloy PJ, Soliman E, Peng X, Kim S, Pike JW, Feldman D, Christakos S. Enhanced coactivator binding and transcriptional activation of mutant vitamin D receptors from patients with hereditary 1,25-dihydroxyvitamin D-resistant rickets by phosphorylation and vitamin D analogs. J Bone Miner Res 2005 20(9):1680-91 PubMed ID: 16059639 DOI: 10.1359/JBMR.050410

6858 Yo Shibata, Takashi Miyazaki Antibacterial titanium plate anodized by discharging in NaCl solution exhibits cell compatibility International Congress Series 2005 1284:284-289 DOI: 10.1016/j.ics.2005.07.064

6859 Nakamura Y, Wakitani S, Saito N, Takaoka K. Expression profiles of BMP-related molecules induced by BMP-2 or -4 in muscle-derived primary culture cells. J Bone Miner Metab 2005 23(6):426-34 PubMed ID: 16261448 DOI: 10.1007/s00774-005-0624-5

6860 Oshima T, Abe M, Asano J, Hara T, Kitazoe K, Sekimoto E, Tanaka Y, Shibata H, Hashimoto T, Ozaki S, Kido S, Inoue D, Matsumoto T. Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2. Blood 2005 106(9):3160-5 PubMed ID: 16030194 DOI: 10.1182/blood-2004-12-4940

6861 Kimura T, Sato Y, Kimura F, Iwasaka M, Ueno S. Micropatterning of cells using modulated magnetic fields. Langmuir 2005 21(3):830-2 PubMed ID: 15667156 DOI: 10.1021/la047517z

6863 Carey LE, Xu HH, Simon CG Jr, Takagi S, Chow LC. Premixed rapid-setting calcium phosphate composites for bone repair. Biomaterials. 2005 26(24):5002-14 PubMed ID: 15769536 DOI: 10.1016/j.biomaterials.2005.01.015

6864 Sakuma-Zenke M, Sakai A, Nakayamada S, Kunugita N, Tabata T, Uchida S, Tanaka S, Mori T, Nakai K, Tanaka Y, Nakamura T. Reduced expression of platelet endothelial cell adhesion molecule-1 in bone marrow cells in mice after skeletal unloading. J Bone Miner Res 2005 20(6):1002-10 PubMed ID: 15883641 DOI: 10.1359/JBMR.050102

6865 Tamada Y. New process to form a silk fibroin porous 3-D structure. Biomacromolecules 2005 6(6):3100-6 PubMed ID: 16283733 DOI: 10.1021/bm050431f

6867 Hirata I, Nomura Y, Tabata H, Miake Y, Yanagisawa T, Okazaki M. SEM observation of collagen fibrils secreted from the body surface of osteoblasts on a CO3apatite-collagen sponge. Dent Mater J 2005 24(3):460-4 PubMed ID: 16279740 DOI: 10.4012/dmj.24.460

8188 Lieve Verlinden, Guy Eelen, Ine Beullens, Mark Van Camp, Paul Van Hummelen, Kristof Engelen, Ruth Van Hellemont, Kathleen Marchal, Bart De Moor, Floris Foijer Characterization of the Condensin Component Cnap1 and Protein Kinase Melk as Novel E2F Target Genes Downregulated by 1,25-Dihydroxyvitamin D3 JOURNAL OF BIOLOGICAL CHEMISTRY 2005 280:37319 –37330

15418 Jing Xi, Yuan Gao, Lijun Kong, Yandao Gong, Nanming Zhao, Xiufang Zhang Behavior of MC3T3-El osteoblast cultured on chitosan modified with polyvinylpyrrolidone Tsinghua Science and Technology 2005 10:339-444 DOI: 10.1016/s1007-0214(05)70097-3

15419 T. ADACHI, K. SATO OSTEOBLASTIC MECHANOSENSITIVITY TO LOCALIZED MECHANICAL STIMULUS DEPENDS ON ORIENTATION OF CYTOSKELETAL ACTIN FIBERS Biomechanics At Micro- And Nanoscale Levels 2005 55-64 DOI: 10.1142/9789812569301_0005

15420 M. Kumaoka, T. Shiraishi, S. Morishita Effects of Mechanical Vibration on Osteoblast-Like Cell Line Advances in Bioengineering 2005 DOI: 10.1115/imece2005-81980

5569 Katsuyama H, Otsuki T, Tomita M, Fukunaga M, Fukunaga T, Suzuki N, Saijoh K, Fushimi S, Sunami S. Menaquinone-7 regulates the expressions of osteocalcin, OPG, RANKL and RANK in osteoblastic MC3T3E1 cells Int J Mol Med 2005 15(2):231-6 PubMed ID: 15647836

3158 Nishimura, Haruki, Nishimura, Masahiro, Oda, Ryo, Yamanaka, Katsuyuki, Matsubara, Takehiro, Ozaki, Yoshie, Sekiya, Kensuke, Hamada, Taizo, Kato, Yukio Lectins induce resistance to proteases and/or mechanical stimulus in all examined cells--including bone marrow mesenchymal stem cells--on various scaffolds. Exp Cell Res 2004 295:119-27 PubMed ID: 15051495 DOI: 10.1016/j.yexcr.2003.12.018

2726 Inoue M, LeGeros RZ, Inoue M, Tsujigiwa H, Nagatsuka H, Yamamoto T, Nagai N In vitro response of osteoblast-like and odontoblast-like cells to unsubstituted and substituted apatites J Biomed Mater Res 2004 70A:585-593 PubMed ID: 15307163 DOI: 10.1002/jbm.a.30116

2870 Fukuyama R, Fujita T, Azuma Y, Hirano A, Nakamuta H, Koida M, Komori T Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling. Biochem Biophys Res Commun 2004 315:636-42 PubMed ID: 14975748 DOI: 10.1016/j.bbrc.2004.01.104

2871 Notoya M, Otsuka E, Yamaguchi A, Hagiwara H Runx-2 is not essential for the vitamin D-regulated expression of RANKL and osteoprotegerin in osteoblastic cells. Biochem Biophys Res Commun 2004 324:655-60 PubMed ID: 15474477 DOI: 10.1016/j.bbrc.2004.09.101

3051 Mogi M, Ozeki N, Nakamura H, Togari A Dual roles for NF-kappaB activation in osteoblastic cells by serum deprivation: osteoblastic apoptosis and cell-cycle arrest. Bone 2004 35:507-16 PubMed ID: 15268903 DOI: 10.1016/j.bone.2004.03.003

2822 Zhang, Gui Xia, Mizuno, Morimichi, Tsuji, Kiyomi, Tamura, Masato Regulation of mRNA expression of matrix extracellular phosphoglycoprotein (MEPE)/ osteoblast/osteocyte factor 45 (OF45) by fibroblast growth factor 2 in cultures of rat bone marrow-derived osteoblastic cells. Endocrine 2004 24:15-24 PubMed ID: 15249699 DOI: 10.1385/ENDO:24:1:015

2926 French, Dorothy M, Kaul, Raji J, D'Souza, Aloma L, Crowley, Craig W, Bao, Min, Frantz, Gretchen D, Filvaroff, Ellen H, Desnoyers, Luc WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair. Am J Pathol 2004 165:855-67 PubMed ID: 15331410 DOI: 10.1016/S0002-9440(10)63348-2

3096 Sogo Y. et al. Zinc containing hydroxyapatite ceramics to promote osteoblastic cell activity. Materials Schience and Technology 2004 20:1079-1083 DOI: 10.1179/026708304225019704

5415 Saito M, Soshi S, Tanaka T, Fujii K. Intensity-related differences in collagen post-translational modification in MC3T3-E1 osteoblasts after exposure to low- and high-intensity pulsed ultrasound. Bone 2004 35(3):644-55 PubMed ID: 15336600 DOI: 10.1016/j.bone.2004.04.024

6711 J Steroid Biochem Mol Biol Microarray analysis of 1alpha,25-dihydroxyvitamin D3-treated MC3T3-E1 cells. Eelen G, Verlinden L, Van Camp M, Mathieu C, Carmeliet G, Bouillon R, Verstuyf A. 2004 89-90(1-5):405-7. PubMed ID: 15225810 DOI: 10.1016/j.jsbmb.2004.03.008

6712 Kanno S, Hirano S, Kayama F. Effects of phytoestrogens and environmental estrogens on osteoblastic differentiation in MC3T3-E1 cells. Toxicology 2004 196(1-2):137-45 PubMed ID: 15036763 DOI: 10.1016/j.tox.2003.12.002

6713 Effect of low- and high-intensity pulsed ultrasound on collagen post-translational modifications in MC3T3-E1 osteoblasts. Calcif Tissue Int 2004 75(5):384-95. Epub 2004 Jul 13 PubMed ID: 15592795 DOI: 10.1007/s00223-004-0292-9

6714 Date T, Doiguchi Y, Nobuta M, Shindo H. Bone morphogenetic protein-2 induces differentiation of multipotent C3H10T1/2 cells into osteoblasts, chondrocytes, and adipocytes in vivo and in vitro. J Orthop Sci 2004 9(5):503-8 PubMed ID: 15449126 DOI: 10.1007/s00776-004-0815-2

6715 Hanks T, Atkinson BL. Comparison of cell viability on anorganic bone matrix with or without P-15 cell binding peptide. Biomaterials 2004 25(19):4831-6 PubMed ID: 15120530 DOI: 10.1016/j.biomaterials.2003.12.007

6716 Yoshizawa T, Takizawa F, Iizawa F, Ishibashi O, Kawashima H, Matsuda A, Endo N, Kawashima H. Homeobox protein MSX2 acts as a molecular defense mechanism for preventing ossification in ligament fibroblasts. Mol Cell Biol 2004 24(8):3460-72 PubMed ID: 15060165 DOI: 10.1128/mcb.24.8.3460-3472.2004

6717 Simon CG Jr. Imaging cells on polymer spherulites. J Microsc 2004 216(Pt 2):153-5 PubMed ID: 15516226 DOI: 10.1111/j.0022-2720.2004.01401.x

6718 Washburn NR, Yamada KM, Simon CG Jr, Kennedy SB, Amis EJ. High-throughput investigation of osteoblast response to polymer crystallinity: influence of nanometer-scale roughness on proliferation. Biomaterials 2004 25(7-8):1215-24 PubMed ID: 14643595 DOI: 10.1016/j.biomaterials.2003.08.043

6719 Norio Amizuka et al Morphological Approach to Biological Action of PTHrP and Vitamin D3 on Endochondral Ossification Journal of Oral Biosciences 2004 46:79-96 DOI: 10.1016/S1349-0079(04)80020-3

6720 Ogasawara T, Kawaguchi H, Jinno S, Hoshi K, Itaka K, Takato T, Nakamura K, Okayama H. Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6. Mol Cell Biol. 2004 24(15):6560-8 PubMed ID: 15254224 DOI: 10.1128/MCB.24.15.6560-6568.2004

6721 Eelen G, Verlinden L, van Camp M, van Hummelen P, Marchal K, de Moor B, Mathieu C, Carmeliet G, Bouillon R, Verstuyf A. The effects of 1alpha,25-dihydroxyvitamin D3 on the expression of DNA replication genes. J Bone Miner Res 2004 19(1):133-46 PubMed ID: 14753745 DOI: 10.1359/JBMR.0301204

6722 Papoutsi Z, Kassi E, Papaevangeliou D, Pratsinis H, Zoumpourlis V, Halabalaki M, Mitakou S, Kalofoutis A, Moutsatsou P. Plant 2-arylobenzofurans demonstrate a selective estrogen receptor modulator profile. Steroids 2004 69(11-12):727-34 PubMed ID: 15579325 DOI: 10.1016/j.steroids.2004.07.005

6723 Keselowsky BG, Collard DM, García AJ. Surface chemistry modulates focal adhesion composition and signaling through changes in integrin binding. Biomaterials 2004 25(28):5947-54 PubMed ID: 15183609 DOI: 10.1016/j.biomaterials.2004.01.062

6724 Patil C, Zhu X, Rossa C Jr, Kim YJ, Kirkwood KL. p38 MAPK regulates IL-1beta induced IL-6 expression through mRNA stability in osteoblasts. Immunol Invest 2004 33(2):213-33 PubMed ID: 15195698 DOI: 10.1081/imm-120034231

6725 Xu HH, Simon CG Jr. Self-hardening calcium phosphate composite scaffold for bone tissue engineering. J Orthop Res 2004 22(3):535-43 PubMed ID: 15099632 DOI: 10.1016/j.orthres.2003.09.010

6726 Masayuki OKAZAKI New Type Scaffold Biomaterials with Magnesium Accelerating Osteoblast Adhesion and Bone Formation Journal of Oral Tissue Engineering 2004 1:31-40 DOI: 10.11223/jarde.1.31

6727 Hikiji H, Ishii S, Shindou H, Takato T, Shimizu T. Absence of platelet-activating factor receptor protects mice from osteoporosis following ovariectomy. J Clin Invest 2004 114(1):85-93 PubMed ID: 15232615 DOI: 10.1172/JCI20504

6729 Itoh M, Shimazu A, Hirata I, Yoshida Y, Shintani H, Okazaki M. Characterization of CO3Ap-collagen sponges using X-ray high-resolution microtomography. Biomaterials 2004 25(13):2577-83 PubMed ID: 14751743 DOI: 10.1016/j.biomaterials.2003.09.071

6730 Xu HH, Smith DT, Simon CG. Strong and bioactive composites containing nano-silica-fused whiskers for bone repair. Biomaterials 2004 25(19):4615-26 PubMed ID: 15120507 DOI: 10.1016/j.biomaterials.2003.12.058

6731 Tieliewuhan Y, Hirata I, Sasaki A, Minagi H, Okazaki M. Osteoblast proliferation behavior and bone formation on and in CO3apatite-collagen sponges with a porous hydroxyapatite frame. Dent Mater J 2004 23(3):258-64 PubMed ID: 15510851 DOI: 10.4012/dmj.23.258

6732 Taiji Adachit, Katsuya Sato, Mamoru Matsuo, and Yoshihiro Tomitai Evaluation of Axial Strain in Stress Fibers Inducing Cytoskeletal Reorganization in Osteoblastic Cells(Micro- and Nano-biomechanics) First Asian Pacific Conference on Biomechanics 2004

6733 Xu HH, Simon CG Jr. Self-hardening calcium phosphate cement-mesh composite: reinforcement, macropores, and cell response. J Biomed Mater Res A 2004 69(2):267-78 PubMed ID: 15057999 DOI: 10.1002/jbm.a.20124

6734 Reyes CD, García AJ. Alpha2beta1 integrin-specific collagen-mimetic surfaces supporting osteoblastic differentiation. J Biomed Mater Res A 2004 69(4):591-600 PubMed ID: 15162400 DOI: 10.1002/jbm.a.30034

6735 Carl G. Simon Jr. William F. Guthrie Francis W. Wang Cell seeding into calcium phosphate cement Journal of Biomedical Materials Research Part A 2004 68A:628-639 PubMed ID: 14986318 DOI: 10.1002/jbm.a.20008

6736 Takada T, Suzuki N, Ito-Kato E, Noguchi Y, Ito M, Maeno M, Otsuka K Effect of beta-alanyl-L-histidinato zinc on the differentiation of C2C12 cells. Life Sci 2004 76(5):509-20 PubMed ID: 15556164 DOI: 10.1016/j.lfs.2004.06.014

6737 Naruse M, Otsuka E, Naruse M, Ishihara Y, Miyagawa-Tomita S, Hagiwara H. Inhibition of osteoclast formation by 3-methylcholanthrene, a ligand for arylhydrocarbon receptor: suppression of osteoclast differentiation factor in osteogenic cells. Biochem Pharmacol 2004 67(1):119-27 PubMed ID: 14667934 DOI: 10.1016/j.bcp.2003.08.038

6740 Shinsuke AOKI, Shunro YAMAGUCHI, Atsushi NAKAHIRA, Katsuaki SUGANUMA Preparation of Porous Calcium Phosphates Using a Ceramic Foaming Technique Combined with a Hydrothermal Treatment and the Cell Response with Incorporation of Osteoblast-Like Cells Journal of the Ceramic Society of Japan 2004 112:193-199 DOI: 10.2109/jcersj.112.193

5563 Shibata Y, Kawai H, Yamamoto H, Igarashi T, Miyazaki T. Antibacterial titanium plate anodized by being discharged in NaCl solution exhibits cell compatibility J Dent Res 2004 83(2):115-9 PubMed ID: 14742647 DOI: 10.1177/154405910408300206

5566 Kawazoe Y, Shiba T, Nakamura R, Mizuno A, Tsutsumi K, Uematsu T, Yamaoka M, Shindoh M, Kohgo T. Induction of calcification in MC3T3-E1 cells by inorganic polyphosphate J Dent Res 2004 83(8):613-8 PubMed ID: 15271969 DOI: 10.1177/154405910408300806

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3049 Mogi M, Togari A Activation of caspases is required for osteoblastic differentiation. J Biol Chem 2003 278:47477-82 PubMed ID: 12954609 DOI: 10.1074/jbc.M307055200

3050 Arai M., Nagasawa T., Tsunashima Y., Matsuda T., Kawamura H., Mogi M., Togari A. A simple and useful method for evaluating biocompatibility of titanium alloy with heterotopic bone induced by demineralized bone matrix (DBM) pellet in mice. Oral Therapeutics Pharmacology 2003 22:117-125

6273 Tanigaki K, Sasaki S, Ohkuma S. In bafilomycin A1-resistant cells, bafilomycin A1 raised lysosomal pH and both prodigiosins and concanamycin A inhibited growth through apoptosis. FEBS Lett 2003 537(1-3):79-84 PubMed ID: 12606035 DOI: 10.1016/s0014-5793(03)00084-x

4964 Gruber R, Graninger W, Bobacz K, Watzek G, Erlacher L. BMP-6-induced osteogenic differentiation of mesenchymal cell lines is not modulated by sex steroids and resveratrol. Cytokine 2003 23(4-5):133-7 PubMed ID: 12967649 DOI: 10.1016/s1043-4666(03)00223-0

3535 Ehara A, Ogata K, Imazato S, Ebisu S, Nakano T, Umakoshi Y. Effects of alpha-TCP and TetCP on MC3T3-E1 proliferation, differentiation and mineralization. Biomaterials 2003 24(5):831-6 PubMed ID: 12485801 DOI: 10.1016/s0142-9612(02)00411-8

3870 Kim H, Arakawa H, Osada T, Ikai A. Quantification of cell adhesion force with AFM: distribution of vitronectin receptors on a living MC3T3-E1 cell. Ultramicroscopy 2003 97(1-4):359-63 PubMed ID: 12801689 DOI: 10.1016/S0304-3991(03)00061-5

3895 Isama K, Tsuchiya T. Enhancing effect of poly(L-lactide) on the differentiation of mouse osteoblast-like MC3T3-E1 cells. Biomaterials 2003 24(19):3303-9 PubMed ID: 12763458 DOI: 10.1016/s0142-9612(03)00216-3

4083 Saito M, Soshi S, Fujii K. Effect of hyper- and microgravity on collagen post-translational controls of MC3T3-E1 osteoblasts. J Bone Miner Res 2003 18(9):1695-705 PubMed ID: 12968680 DOI: 10.1359/jbmr.2003.18.9.1695

4415 Itoh F, Aoyagi S, Furihata-Komatsu H, Aoki M, Kusama H, Kojima M, Kogo H. Clodronate stimulates osteoblast differentiation in ST2 and MC3T3-E1 cells and rat organ cultures. Eur J Pharmacol 2003 477(1):9-16 PubMed ID: 14512092 DOI: 10.1016/j.ejphar.2003.08.011

4610 Suzuki H, Nezaki Y, Kuno E, Sugiyama I, Mizutani A, Tsukagoshi N. Functional roles of the tissue inhibitor of metalloproteinase 3 (TIMP-3) during ascorbate-induced differentiation of osteoblastic MC3T3-E1 cells. Biosci Biotechnol Biochem 2003 67(8):1737-43 PubMed ID: 12951508 DOI: 10.1271/bbb.67.1737

4766 Aoshima Y, Hasegawa Y, Hasegawa S, Nagasaka A, Kimura T, Hashimoto S, Torii Y, Tsukagoshi N. Isolation of GnafC, a polysaccharide constituent of Gnaphalium affine, and synergistic effects of GnafC and ascorbate on the phenotypic expression of osteoblastic MC3T3-E1 cells. Biosci Biotechnol Biochem 2003 67(10):2068-74 PubMed ID: 14586092 DOI: 10.1271/bbb.67.2068

4926 Bhattacharyya RS, Stern PH. IGF-I and MAP kinase involvement in the stimulatory effects of LNCaP prostate cancer cell conditioned media on cell proliferation and protein synthesis in MC3T3-E1 osteoblastic cells. J Cell Biochem 2003 90(5):925-37 PubMed ID: 14624452 DOI: 10.1002/jcb.10726

4952 Choi EM, Hwang JK. Effects of (+)-catechin on the function of osteoblastic cells. Biol Pharm Bull 2003 26(4):523-6 PubMed ID: 12673036 DOI: 10.1248/bpb.26.523

4955 Itano N, Okamoto S, Zhang D, Lipton SA, Ruoslahti E. Cell spreading controls endoplasmic and nuclear calcium: a physical gene regulation pathway from the cell surface to the nucleus. Proc Natl Acad Sci U S A 2003 100(9):5181-6 PubMed ID: 12702768 DOI: 10.1073/pnas.0531397100

4961 Takada T, Katagiri T, Ifuku M, Morimura N, Kobayashi M, Hasegawa K, Ogamo A, Kamijo R. Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins. J Biol Chem 2003 278(44):43229-35 PubMed ID: 12912996 DOI: 10.1074/jbc.M300937200

4978 Lee MH, Kwon TG, Park HS, Wozney JM, Ryoo HM. BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2. Biochem Biophys Res Commun 2003 309(3):689-94 PubMed ID: 12963046 DOI: 10.1016/j.bbrc.2003.08.058

5039 Murata T, Sugatani T, Shimizu K, Manganiello VC, Tagawa T. Effect of the phosphodiesterase 4 inhibitor, rolipram, on retinoic acid-increased alkaline phosphatase activity in the mouse fibroblastic C3H10T1/2 cell line. Arch Oral Biol 2003 48(1):63-7 PubMed ID: 12615143 DOI: 10.1016/s0003-9969(02)00166-8

5061 Yamasaki Y, Yoshida Y, Okazaki M, Shimazu A, Kubo T, Akagawa Y, Uchida T. Action of FGMgCO3Ap-collagen composite in promoting bone formation. Biomaterials 2003 24(27):4913-20 PubMed ID: 14559004 DOI: 10.1016/s0142-9612(03)00414-9

5091 Osada T, Uehara H, Kim H, Ikai A. mRNA analysis of single living cells. J Nanobiotechnology 2003 1(1):2 PubMed ID: 12646067 DOI: 10.1186/1477-3155-1-2

5465 Duarte WR, Shibata T, Takenaga K, Takahashi E, Kubota K, Ohya K, Ishikawa I, Yamauchi M, Kasugai S. S100A4: a novel negative regulator of mineralization and osteoblast differentiation. J Bone Miner Res 2003 18(3):493-501 PubMed ID: 12619934 DOI: 10.1359/jbmr.2003.18.3.493

5469 Meredith JC, Sormana JL, Keselowsky BG, García AJ, Tona A, Karim A, Amis EJ. Combinatorial characterization of cell interactions with polymer surfaces. J Biomed Mater Res A 2003 66(3):483-90 PubMed ID: 12918030 DOI: 10.1002/jbm.a.10004

5527 Tohjima E, Inoue D, Yamamoto N, Kido S, Ito Y, Kato S, Takeuchi Y, Fukumoto S, Matsumoto T. Decreased AP-1 activity and interleukin-11 expression by bone marrow stromal cells may be associated with impaired bone formation in aged mice. J Bone Miner Res 2003 18(8):1461-70 PubMed ID: 12929935 DOI: 10.1359/jbmr.2003.18.8.1461

6354 Ito T, Tokunaga K, Maruyama H, Kawashima H, Kitahara H, Horikoshi T, Ogose A, Hotta Y, Kuwano R, Katagiri H, Endo N. Coxsackievirus and adenovirus receptor (CAR)-positive immature osteoblasts as targets of adenovirus-mediated gene transfer for fracture healing. Gene Ther 2003 10(18):1623-8 PubMed ID: 12907955 DOI: 10.1038/sj.gt.3302060

6457 Reyes CD, García AJ. A centrifugation cell adhesion assay for high-throughput screening of biomaterial surfaces. J Biomed Mater Res A 2003 67(1):328-33 PubMed ID: 14517892 DOI: 10.1002/jbm.a.10122

6574 Kirkwood K, Martin T, Andreadis ST, Kim YJ. Chemically modified tetracyclines selectively inhibit IL-6 expression in osteoblasts by decreasing mRNA stability. Biochem Pharmacol 2003 66(9):1809-19 PubMed ID: 14563491 DOI: 10.1016/s0006-2952(03)00450-7

6608 Cutler SM, García AJ. Engineering cell adhesive surfaces that direct integrin alpha5beta1 binding using a recombinant fragment of fibronectin. Biomaterials 2003 24(10):1759-70 PubMed ID: 12593958 DOI: 10.1016/s0142-9612(02)00570-7

6626 Verlinden L, Verstuyf A, Verboven C, Eelen G, De Ranter C, Gao LJ, Chen YJ, Murad I, Choi M, Yamamoto K, Yamada S, Van Haver D, Vandewalle M, De Clercq PJ, Bouillon R. Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity. J Biol Chem 2003 278(37):35476-82 PubMed ID: 12829710 DOI: 10.1074/jbc.M302045200

6628 Abe T, Hikiji H, Shin WS, Koshikiya N, Shima S, Nakata J, Susami T, Takato T, Toyo-oka T. Targeting of iNOS with antisense DNA plasmid reduces cytokine-induced inhibition of osteoblastic activity. Am J Physiol Endocrinol Metab 2003 285(3):E614-21 PubMed ID: 12657566 DOI: 10.1152/ajpendo.00267.2002

6646 Reyes CD, García AJ. Engineering integrin-specific surfaces with a triple-helical collagen-mimetic peptide. J Biomed Mater Res A 2003 65(4):511-23 PubMed ID: 12761842 DOI: 10.1002/jbm.a.10550

5561 Taira M, Nakao H, Takahashi J, Araki Y. Effects of two vitamins, two growth factors and dexamethasone on the proliferation of rat bone marrow stromal cells and osteoblastic MC3T3-E1 cells J Oral Rehabil 2003 30(7):697-701 PubMed ID: 12791154 DOI: 10.1046/j.1365-2842.2003.01118.x

2773 Sakiyama H, Nonaka T, Masuda R, Inoue N, Kuboki Y, Iijima M, Hirabayasi Y, Takahagi M, Yoshida K, Kuriiwa K, Yoshida M, Imajoh-Ohmi S Characterization of mineral deposits formed in cultures of a hamster tartrate-resistant acid phosphatase (TRAP) and alkaline phosphatase (ALP) double-positive cell line (CCP). Cell Tissue Res 2002 309:269-79 PubMed ID: 12172786 DOI: 10.1007/s00441-002-0587-y

3048 Ozeki, Nobuaki, Mogi, Makio, Nakamura, Hiroshi, Togari, Akifumi Differential expression of the Fas-Fas ligand system on cytokine-induced apoptotic cell death in mouse osteoblastic cells. Arch Oral Biol 2002 47:511-7 PubMed ID: 12208075 DOI: 10.1016/s0003-9969(02)00035-3

5980 Byers BA1, Pavlath GK, Murphy TJ, Karsenty G, García AJ. Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal. J Bone Miner Res 2002 17(11):1931-44 PubMed ID: 12412799 DOI: 10.1359/jbmr.2002.17.11.1931

3519 Higuchi C, Myoui A, Hashimoto N, Kuriyama K, Yoshioka K, Yoshikawa H, Itoh K. Continuous inhibition of MAPK signaling promotes the early osteoblastic differentiation and mineralization of the extracellular matrix. J Bone Miner Res 2002 17(10):1785-94 PubMed ID: 12369782 DOI: 10.1359/jbmr.2002.17.10.1785

3557 Tezuka K, Yasuda M, Watanabe N, Morimura N, Kuroda K, Miyatani S, Hozumi N. Stimulation of osteoblastic cell differentiation by Notch. J Bone Miner Res 2002 17(2):231-9 PubMed ID: 11811553 DOI: 10.1359/jbmr.2002.17.2.231

3560 Fujita T, Meguro T, Fukuyama R, Nakamuta H, Koida M. New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP. J Biol Chem 2002 277(25):22191-200 PubMed ID: 11956184 DOI: 10.1074/jbc.M110364200

3570 Shiroki K, Ohsawa C, Sugi N, Wakiyama M, Miura K, Watanabe M, Suzuki Y, Sugano S. Internal ribosome entry site-mediated translation of Smad5 in vivo: requirement for a nuclear event. Nucleic Acids Res 2002 30(13):2851-61 PubMed ID: 12087169 DOI: 10.1093/nar/gkf408

6667 Hata K, Sugawara F, Ohisa N, Takahashi S, Hori K. Stimulative effects of (22E,24R)-ergosta-7,22-diene-3beta,5alpha,6beta-triol from fruiting bodies of Tricholoma auratum, on a mouse osteoblastic cell line, MC3T3-E1. Biol Pharm Bull 2002 25(8):1040-4 PubMed ID: 12186406 DOI: 10.1248/bpb.25.1040

6668 Isama K, Tsuchiya T. Effect of gamma-ray irradiated poly(L-lactide) on the differentiation of mouse osteoblast-like MC3T3-E1 cells. J Biomater Sci Polym Ed 2002 13(2):153-66 PubMed ID: 12022747 DOI: 10.1163/156856202317414348

6670 Saito Y, Yoshizawa T, Takizawa F, Ikegame M, Ishibashi O, Okuda K, Hara K, Ishibashi K, Obinata M, Kawashima H. A cell line with characteristics of the periodontal ligament fibroblasts is negatively regulated for mineralization and Runx2/Cbfa1/Osf2 activity, part of which can be overcome by bone morphogenetic protein-2. J Cell Sci 2002 115(Pt 21):4191-200 PubMed ID: 12356921 DOI: 10.1242/jcs.00098

6671 Stephansson SN, Byers BA, García AJ. Enhanced expression of the osteoblastic phenotype on substrates that modulate fibronectin conformation and integrin receptor binding. Biomaterials 2002 23(12):2527-34 PubMed ID: 12033600 DOI: 10.1016/s0142-9612(01)00387-8

6672 Amizuka N, Oda K, Shimomura J, Maeda T. Biological action of parathyroid hormone (PTH)-related peptide (PTHrP) mediated either by the PTH/PTHrP receptor or the nucleolar translocation in chondrocytes. Anat Sci Int 2002 77(4):225-36 PubMed ID: 12557418 DOI: 10.1046/j.0022-7722.2002.00032.x

6673 Kuriyama K, Higuchi C, Tanaka K, Yoshikawa H, Itoh K. A novel anti-rheumatic drug, T-614, stimulates osteoblastic differentiation in vitro and bone morphogenetic protein-2-induced bone formation in vivo. Biochem Biophys Res Commun 2002 299(5):903-9 PubMed ID: 12470665 DOI: 10.1016/s0006-291x(02)02754-7

6674 Diniz P, Shomura K, Soejima K, Ito G. Effects of pulsed electromagnetic field (PEMF) stimulation on bone tissue like formation are dependent on the maturation stages of the osteoblasts. Bioelectromagnetics 2002 23(5):398-405 PubMed ID: 12111759 DOI: 10.1002/bem.10032

6675 Tsutsumimoto T, Wakabayashi S, Kinoshita T, Horiuchi H, Takaoka K. A phosphodiesterase inhibitor, pentoxifylline, enhances the bone morphogenetic protein-4 (BMP-4)-dependent differentiation of osteoprogenitor cells. Bone 2002 31(3):396-401 PubMed ID: 12231412 DOI: 10.1016/s8756-3282(02)00839-6

6676 Diniz P, Soejima K, Ito G. Nitric oxide mediates the effects of pulsed electromagnetic field stimulation on the osteoblast proliferation and differentiation. Nitric Oxide 2002 7(1):18-23 PubMed ID: 12175815 DOI: 10.1016/s1089-8603(02)00004-6

6678 Inoue A, Kobayashi Y, Ishizuka M, Hirose S, Hagiwara H. Identification of a novel osteoblastic gene, inducible by C-type natriuretic peptide, whose transcript might function in mineralization as a noncoding RNA. Calcif Tissue Int 2002 70(2):111-6 PubMed ID: 11870417 DOI: 10.1007/s00223-001-1012-3

6679 Hinoi E, Fujimori S, Takemori A, Yoneda Y. Cell death by pyruvate deficiency in proliferative cultured calvarial osteoblasts. Biochem Biophys Res Commun 2002 294(5):1177-83 PubMed ID: 12074601 DOI: 10.1016/S0006-291X(02)00578-8

6680 Kubota K, Sakikawa C, Katsumata M, Nakamura T, Wakabayashi K. PDGF BB purified from osteoclasts acts as osteoblastogenesis inhibitory factor (OBIF). J Biomol Tech 2002 13(2):62-71 PubMed ID: 19498968

6681 K. Yamashita ; H. Morimoto ; M. Nakao ; H. Ukai ; T. Hanawa ; T. Ichikawa ; S. Kitamura Intact extracellular matrix can be utilized for bio-integrated materials and tissue engineering IEEE Xplore 2002 DOI: 10.1109/MCTE.2002.1175033

6682 Kubota K, Sakikawa C, Katsumata M, Nakamura T, Wakabayashi K. Platelet-derived growth factor BB secreted from osteoclasts acts as an osteoblastogenesis inhibitory factor. J Bone Miner Res 2002 17(2):257-65 PubMed ID: 11811556 DOI: 10.1359/jbmr.2002.17.2.257

6683 Yamasaki Y, Yoshida Y, Okazaki M, Shimazu A, Uchida T, Kubo T, Akagawa Y, Hamada Y, Takahashi J, Matsuura N. Synthesis of functionally graded MgCO3 apatite accelerating osteoblast adhesion. J Biomed Mater Res 2002 62(1):99-105 PubMed ID: 12124791 DOI: 10.1002/jbm.10220

6685 Onodera S, Nishihira J, Iwabuchi K, Koyama Y, Yoshida K, Tanaka S, Minami A. Macrophage migration inhibitory factor up-regulates matrix metalloproteinase-9 and -13 in rat osteoblasts. Relevance to intracellular signaling pathways. J Biol Chem 2002 277(10):7865-74 PubMed ID: 11751895 DOI: 10.1074/jbc.M106020200

6686 Naraba H, Yokoyama C, Tago N, Murakami M, Kudo I, Fueki M, Oh-Ishi S, Tanabe T. Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1. J Biol Chem 2002 277(32):28601-8 PubMed ID: 12034740 DOI: 10.1074/jbc.M203618200

6687 Kotani H, Kawaguchi H, Shimoaka T, Iwasaka M, Ueno S, Ozawa H, Nakamura K, Hoshi K. Strong static magnetic field stimulates bone formation to a definite orientation in vitro and in vivo. J Bone Miner Res 2002 17(10):1814-21 PubMed ID: 12369785 DOI: 10.1359/jbmr.2002.17.10.1814

6688 Naruse M, Ishihara Y, Miyagawa-Tomita S, Koyama A, Hagiwara H. 3-Methylcholanthrene, which binds to the arylhydrocarbon receptor, inhibits proliferation and differentiation of osteoblasts in vitro and ossification in vivo. Endocrinology 2002 Sep;143(9):3575-81 PubMed ID: 12193573 DOI: 10.1210/en.2002-220003

6689 Simon CG Jr, Khatri CA, Wight SA, Wang FW. Preliminary report on the biocompatibility of a moldable, resorbable, composite bone graft consisting of calcium phosphate cement and poly(lactide-co-glycolide) microspheres. J Orthop Res 2002 0(3):473-82 PubMed ID: 12038620 DOI: 10.1016/S0736-0266(01)00140-1

6690 Washburn NR1, Simon CG Jr, Tona A, Elgendy HM, Karim A, Amis EJ. Co-extrusion of biocompatible polymers for scaffolds with co-continuous morphology. J Biomed Mater Res 2002 60(1):20-9 PubMed ID: 11835155 DOI: 10.1002/jbm.10049

6692 Wakabayashi S, Tsutsumimoto T, Kawasaki S, Kinoshita T, Horiuchi H, Takaoka K. Involvement of phosphodiesterase isozymes in osteoblastic differentiation. J Bone Miner Res 2002 17(2):249-56 PubMed ID: 11811555 DOI: 10.1359/jbmr.2002.17.2.249

6694 Fujimori S, Hinoi E, Yoneda Y. Functional GABA(B) receptors expressed in cultured calvarial osteoblasts. Biochem Biophys Res Commun 2002 293(5):1445-52 PubMed ID: 12054677 DOI: 10.1016/S0006-291X(02)00405-9

6695 Yoshiko Y, Aubin JE, Maeda N. Stanniocalcin 1 (STC1) protein and mRNA are developmentally regulated during embryonic mouse osteogenesis: the potential of stc1 as an autocrine/paracrine factor for osteoblast development and bone formation. J Histochem Cytochem 2002 50(4):483-92 PubMed ID: 11897801 DOI: 10.1177/002215540205000405

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2480 Maeda T, Abe M, Kurisu K, Jikko A, Furukawa S Molecular cloning and characterization of a novel gene, CORS26, encoding a putative secretory protein and its possible involvement in skeletal development. J Biol Chem 2001 276:3628-34 PubMed ID: 11071891 DOI: 10.1074/jbc.M007898200

2487 Fujita T, Izumo N, Fukuyama R, Meguro T, Nakamuta H, Kohno T, Koida M Phosphate provides an extracellular signal that drives nuclear export of Runx2/Cbfa1 in bone cells. Biochem Biophys Res Commun 2001 280:348-52 PubMed ID: 11162521 DOI: 10.1006/bbrc.2000.4108

2557 Kusumi T, Nishi T, Tanaka M, Tsuchida S, Kudo H A murine osteosarcoma cell line with a potential to develop ossification upon transplantation Jpn J Cancer Res 2001 92:649-658 PubMed ID: 11429054 DOI: 10.1111/j.1349-7006.2001.tb01144.x

2771 Sakiyama H, Masuda R, Inoue N, Yamamoto K, Kuriiwa K, Nakagawa K, Yoshida K Establishment and characterization of macrophage-like cell lines expressing osteoclast-specific markers. J Bone Miner Metab 2001 19:220-7 PubMed ID: 11448014 DOI: 10.1007/s007740170024

3542 Ito H, Akiyama H, Iguchi H, Iyama K, Miyamoto M, Ohsawa K, Nakamura T. Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilage. J Biol Chem 2001 276(26):24023-9 PubMed ID: 11292829 DOI: 10.1074/jbc.M100861200

3552 Izumo N, Fujita T, Nakamuta H, Koida M. Lipophilic statins can be osteogenic by promoting osteoblastic calcification in a Cbfa1- and BMP-2-independent manner. Methods Find Exp Clin Pharmacol 2001 23(7):389-94 PubMed ID: 11771853 DOI: 10.1358/mf.2001.23.7.662123

6649 Lee DH, Park JC, Suh H. Effect of centrifugal force on cellular activity of osteoblastic MC3T3-E1 cells in vitro. Yonsei Med J 2001 42(4):405-10 PubMed ID: 11519082 DOI: 10.3349/ymj.2001.42.4.405

6650 Mizutani A, Sugiyama I, Kuno E, Matsunaga S, Tsukagoshi N. Expression of matrix metalloproteinases during ascorbate-induced differentiation of osteoblastic MC3T3-E1 cells. J Bone Miner Res 2001 16(11):2043-9 PubMed ID: 11697800 DOI: 10.1359/jbmr.2001.16.11.2043

6651 Kanno S, Anuradha CD, Hirano S. Chemotactic responses of osteoblastic MC3T3-E1 cells toward zinc chloride. Biol Trace Elem Res 2001 83(1):49-55 PubMed ID: 11694002 DOI: 10.1385/BTER:83:1:49

6652 Ishibashi O, Yamagishi T, Hanada K, Kawashima H. Tamoxifen agonism and estrogen antagonism of c-fos gene promoter activity through non-consensus-responsive elements in MC3T3-E1 osteoblasts. Biochem Biophys Res Commun 2001 289(3):705-11 PubMed ID: 11726205 DOI: 10.1006/bbrc.2001.6045

6653 Hattori T, Maehashi H, Miyazawa T, Naito M. Potentiation by stannous chloride of calcium entry into osteoblastic MC3T3-E1 cells through voltage-dependent L-type calcium channels. Cell Calcium 2001 30(1):67-72 PubMed ID: 11396989 DOI: 10.1054/ceca.2001.0214

6654 Ishibashi O, Kawashima H. Cloning and characterization of the functional promoter of mouse estrogen receptor beta gene. Biochim Biophys Acta 2001 1519(3):223-9 PubMed ID: 11418189 DOI: 10.1016/s0167-4781(01)00232-9

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6655 Makiishi-Shimobayashi C, Tsujimura T, Iwasaki T, Yamada N, Sugihara A, Okamura H, Hayashi S, Terada N. Interleukin-18 up-regulates osteoprotegerin expression in stromal/osteoblastic cells. Biochem Biophys Res Commun 2001 281(2):361-6 PubMed ID: 11181055 DOI: 10.1006/bbrc.2001.4380

6656 Taira M, Toguchi MS, Hamada Y, Takahashi J, Itou R, Toyosawa S, Ijyuin N, Okazaki M. Studies on cytotoxic effect of nickel ions on three cultured fibroblasts. J Mater Sci Mater Med 2001 12(5):373-6 PubMed ID: 15348274 DOI: 10.1023/a:1011295115612

6657 Kikuchi T, Matsuguchi T, Tsuboi N, Mitani A, Tanaka S, Matsuoka M, Yamamoto G, Hishikawa T, Noguchi T, Yoshikai Y. Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. J Immunol 2001 166(5):3574-9 PubMed ID: 11207318 DOI: 10.4049/jimmunol.166.5.3574

6658 Davis J, Pither RJ. Biochemical responses in cultured cells following exposure to (89)SrCl(2): potential relevance to the mechanism of action in pain palliation. Eur J Cancer 2001 37(18):2464-9 PubMed ID: 11720844 DOI: 10.1016/s0959-8049(01)00305-7

6659 Tamura S, Kataoka H, Matsui Y, Shionoya Y, Ohno K, Michi KI, Takahashi K, Yamaguchi A. The effects of transplantation of osteoblastic cells with bone morphogenetic protein (BMP)/carrier complex on bone repair. Bone 2001 29(2):169-75 PubMed ID: 11502479 DOI: 10.1016/s8756-3282(01)00498-7

6660 Fujita T, Fukuyama R, Izumo N, Hirai T, Meguro T, Nakamuta H, Koida M. Transactivation of core binding factor alpha1 as a basic mechanism to trigger parathyroid hormone-induced osteogenesis. Jpn J Pharmacol 2001 86(4):405-16 PubMed ID: 11569614 DOI: 10.1254/jjp.86.405

3047 Mogi M, Kondo A, Kinpara K, Togari A Anti-apoptotic action of nerve growth factor in mouse osteoblastic cell line. Life Sci 2000 67:1197-206 PubMed ID: 10954053 DOI: 10.1016/s0024-3205(00)00705-0

2484 Taira M, Nakao H, Matsumoto T, Takahashi J Cytotoxic effect of methyl methacrylate on 4 cultured fibroblasts. Int J Prosthodont 2000 13:311-5 PubMed ID: 11203647

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3977 Ikarashi Y, Tsuchiya T, Nakamura A. Effect of heat treatment of poly(L-lactide) on the response of osteoblast-like MC3T3-E1 cells. Biomaterials 2000 21(12):1259-67 PubMed ID: 10811307 DOI: 10.1016/s0142-9612(00)00008-9

3978 Tanioka T, Nakatani Y, Semmyo N, Murakami M, Kudo I. Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis. J Biol Chem 2000 275(42):32775-82 PubMed ID: 10922363 DOI: 10.1074/jbc.M003504200

3980 Hiroko Kotani, Masakazu Iwasaka, and Shoogo Ueno Magnetic orientation of collagen and bone mixture Journal of Applied Physics 2000 87:6191 DOI: 10.1063/1.372652

3981 Ura K, Morimoto I, Watanabe K, Saito K, Yanagihara N, Eto S. Interleukin (IL)-4 and IL-13 inhibit the differentiation of murine osteoblastic MC3T3-E1 cells. Endocr J 2000 47(3):293-302 PubMed ID: 11036873 DOI: 10.1507/endocrj.47.293

3982 Nakatani Y, Tanioka T, Sunaga S, Murakami M, Kudo I. Identification of a cellular protein that functionally interacts with the C2 domain of cytosolic phospholipase A(2)alpha. J Biol Chem 2000 275(2):1161-8 PubMed ID: 10625659 DOI: 10.1074/jbc.275.2.1161

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3985 Hines ER, Collins JF, Ghishan FK. Molecular cloning of the murine PHEX gene promoter. Biochim Biophys Acta 2000 1493(3):333-6 PubMed ID: 11018258 DOI: 10.1016/s0167-4781(00)00188-3

3986 Davis J1, Cook ND, Pither RJ. Biologic mechanisms of 89SrCl2 incorporation into type I collagen during bone mineralization. J Nucl Med 2000 41(1):183-8 PubMed ID: 10647622

3987 Gruber R, Nothegger G, Ho GM, Willheim M, Peterlik M. Differential stimulation by PGE(2) and calcemic hormones of IL-6 in stromal/osteoblastic cells. Biochem Biophys Res Commun 2000 270(3):1080-5 PubMed ID: 10772953 DOI: 10.1006/bbrc.2000.2573

3989 Yoshimasa FUJIMAKI The Role of Recombinant Human Bone Morphogenetic Protein 2 (rhBMP-2) in the Differentiation of Osteoblasts and Chondrocytes The Showa University Journal of Medical Sciences 2000 12:39-49 DOI: 10.15369/sujms1989.12.39

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3292 Kinpara K, Mogi M, Kuzushima M, Togari A. IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-gamma J Immunol 2000 164(11):5833-43 PubMed ID: 10820262 DOI: 10.4049/jimmunol.164.11.5833

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