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Cell No. : Cell Name
RCB1126 : MC3T3-E1  update : 2022/12/05
CommentDifferentiate to osteoblasts. Collagen producing.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Kodama, Hiroaki
Originator Kodama, Hiroaki
Year of deposit 1994
Original cell MC3T3-E1
Animal mouse < Mammals
Strain name C57BL/6
Gender Unknown
Age at sampling 0 day
Tissue newborn, calvaria
Classification other
Lifespan infinite
Morphology fibroblast-like
Cellosaurus(Expasy) CVCL_0409
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives MEM ALPHA + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 4 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
SSLP(mouse) OK
deposit info
lot info
Reference information Reference 8
User's Publication 1203

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1995  Zhou, H Y, Takita H, Fujisawa R, Mizuno M, Kuboki Y  Stimulation by bone sialoprotein of calcification in osteoblast-like MC3T3-E1 cells.  Calcif Tissue Int  1995  56:403-7  PubMed ID: 7621349   DOI: 10.1007/bf00301610
1993  Kobayashi T, Sugimoto T, Saijoh K, Fukase M, Chihara K  Calcitonin directly acts on mouse osteoblastic MC3T3-E1 cells to stimulate mRNA expression of c-fos, insulin-like growth factor-1 and osteoblastic phenotypes (type 1 collagen and osteocalcin).  Biochem Biophys Res Commun  1994  199:876-80  PubMed ID: 8135834   DOI: 10.1006/bbrc.1994.1310
1994  Tsukamoto T, Matsui T, Takaishi T, Ito M, Fukase M, Chihara K  Retinoic acid differentially affects platelet-derived growth factor-regulated cell growth of mouse osteoblast-like cells  Cell Growth Differ  1994  5:207-212  PubMed ID: 8180134  
2590  Yamaguchi A, Katagiri T, Ikeda T, Wozney, J M, Rosen V, Wang, E A, Kahn, A J, Suda T, Yoshiki S  Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro.  J cell Biol  1991  113:681-687  PubMed ID: 1849907   DOI: 10.1083/jcb.113.3.681
1992  Hiura K, Sumitani K, Kawata T, Higashino K, Okawa M, Sato T, Hakeda Y, Kumegawa M  Mouse osteoblastic cells (MC3T3-E1) at different stages of differentiation have opposite effects on osteoclastic cell formation.  Endocrinology  1991  128:1630-7  PubMed ID: 1999177   DOI: 10.1210/endo-128-3-1630
1991  Hakeda Y, Nakatani Y, Hiramatsu M, Kurihara N, Tsunoi M, Ikeda E, Kumegawa M  Inductive effects of prostaglandins on alkaline phosphatase in osteoblastic cells, clone MC3T3-E1  J Biochem  1985  97:97-104  PubMed ID: 2581942   DOI: 10.1093/oxfordjournals.jbchem.a135072
1849  Sudo H, Kodama, H A, Amagai Y, Yamamoto S, Kasai S  In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria.  J Cell Biol  1983  96:191-198  PubMed ID: 6826647   DOI: 10.1083/jcb.96.1.191
1848  Kodama,H., Amagai,Y., Sudo,H., Kasai,S. and Yamamoto,S.  Establishment of a clonal osteogenic cell line from newborn mouse calvaria  Jpn J Oral Biol  1981  23:899-901    DOI: 10.2330/joralbiosci1965.23.899

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User's Publication
20844  Suzuki M, Kimura T, Nakano Y, Kobayashi M, Okada M, Matsumoto T, Nakamura N, Hashimoto Y, Kishida A.  Preparation of mineralized pericardium by alternative soaking for soft-hard interregional tissue application.  J Biomed Mater Res A  2023  111(2):198-208  PubMed ID: 36069375   DOI: 10.1002/jbm.a.37445
20397  Vukoje I, Lazić V, Sredojević D, Fernandes MM, Lanceros-Mendez S, Ahrenkiel SP, Nedeljković JM.  Influence of glucose, sucrose, and dextran coatings on the stability and toxicity of silver nanoparticles.  Int J Biol Macromol  2022    PubMed ID: 34800522   DOI: 10.1016/j.ijbiomac.2021.11.089
20461  Tan T, Zhao Q, Kuwae H, Ueno T, Chen P, Tsutsumi Y, Mizuno J, Hanawa T, Wakabayashi N.  Surface properties and biocompatibility of sandblasted and acid-etched titanium-zirconium binary alloys with various compositions.  Dent Mater J  2022    PubMed ID: 34866118   DOI: 10.4012/dmj.2021-210
15894  Moreira J, Fernandes MM, Carvalho EO, Nicolau A, Lazic V, Nedeljković JM, Lanceros-Mendez S.  Exploring electroactive microenvironments in polymer-based nanocomposites to sensitize bacterial cells to low-dose embedded silver nanoparticles  Acta Biomater  2022  S1742-7061(21)00505-5  PubMed ID: 34358697   DOI: 10.1016/j.actbio.2021.07.067
20465  Shimabukuro M, Hayashi K, Kishida R, Tsuchiya A, Ishikawa K.  No-Observed-Effect Level of Silver Phosphate in Carbonate Apatite Artificial Bone on Initial Bone Regeneration.  ACS Infect Dis  2022    PubMed ID: 34875165   DOI: 10.1021/acsinfecdis.1c00480
20500  Negishi T, Mihara N, Chiba T, D'Armiento J, Chada K, Maeda M, Igarashi M, Imai K.  High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development.High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development.High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development.High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development.  Biochem Biophys Res Commun  2022  590:68-74  PubMed ID: 34973532   DOI: 10.1016/j.bbrc.2021.12.093
20532  Patty DJ, Nugraheni AD, Ana ID, Yusuf Y.  In vitro bioactivity of 3D microstructure hydroxyapatite/collagen based-egg white as an antibacterial agent.  J Biomed Mater Res B Appl Biomater  2022    PubMed ID: 35040555   DOI: 10.1002/jbm.b.35009
20539  Migita S, Wakabayashi K, Yamazaki T.  Binding stability of peptides to Co-Cr-Mo alloy affects proliferation and differentiation of osteoblast.  Biotechnol Bioeng  2022    PubMed ID: 35067921   DOI: 10.1002/bit.28041
20549  Ikezaki-Amada K, Miyamoto Y, Sasa K, Yamada A, Kinoshita M, Yoshimura K, Kawai R, Yano F, Shirota T, Kamijo R.  Extracellular acidification augments sclerostin and osteoprotegerin production by Ocy454 mouse osteocytes.  Biochem Biophys Res Commun  2022  597:44-51  PubMed ID: 35123265   DOI: 10.1016/j.bbrc.2022.01.111
20563  Sato H, Chen P, Ashida M, Tsutsumi Y, Harada H, Hanawa T.  Evaluation of cytocompatibility and osteoconductivity of Zr-14Nb-5Ta-1Mo alloy with MC3T3-E1 cells.  Dent Mater J  2022    PubMed ID: 35135939   DOI: 10.4012/dmj.2021-169
20527  Hayashi K, Shimabukuro M, Ishikawa K.  Antibacterial Honeycomb Scaffolds for Achieving Infection Prevention and Bone Regeneration.  ACS Appl Mater Interfaces  2022    PubMed ID: 35020349   DOI: 10.1021/acsami.1c20204
16319  Fukuyasu S, Kayashima H, Moribayashi A, Matsuoka S, Nagasaki A, Okawa H, Yatani H, Saeki M, Egusa H.  Cell-Based Double-Screening Method to Identify a Reliable Candidate for Osteogenesis-Targeting Compounds  Biomedicines  2022  10(2):426  PubMed ID: 35203635   DOI: 10.3390/biomedicines10020426
16323  Nomura S, Kono R, Imaoka M, Tazaki F, Okuno Y, Utsunomiya H, Takeda M, Nakamura M.  Traditional Japanese apricot (Prunus mume) induces osteocalcin in osteoblasts  Biosci Biotechnol Biochem  2022  zbac013  PubMed ID: 35150233   DOI: 10.1093/bbb/zbac013
16326  Patty DJ, Nugraheni AD, Ana ID, Yusuf Y.  Dual functional carbonate-hydroxyapatite nanocomposite from Pinctada maxima and egg-white for bone tissue engineering  J Biomater Sci Polym Ed  2022  1-20  PubMed ID: 35107394   DOI: 10.1080/09205063.2022.2036934
16327  Yoshida G, Kawabata T, Takamatsu H, Saita S, Nakamura S, Nishikawa K, Fujiwara M, Enokidani Y, Yamamuro T, Tabata K, Hamasaki M, Ishii M, Kumanogoh A, Yoshimori T.  Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis  Autophagy  2022  1-10  PubMed ID: 35025696   DOI: 10.1080/15548627.2021.2017587
16343  Chikahiro Imashiro, Yuta Ida, Shogo Miyata, Jun Komotori  Titanium Culture Vessel Capable of Controlling Culture Temperature for Evaluation of Cell Thermotolerance  MATERIALS TRANSACTIONS  2022  63:373-378    DOI: 10.2320/
16344  Waheed H, Farrukh S, Hussain A, Mukhtar A, Mubashir M, Saqib S, Ullah S, Peter AP, Khoo KS, Show PL.  Green synthesized nano-cellulose polyethylene imine-based biological membrane.  Food Chem Toxicol  2022  160:112773  PubMed ID: 34953965   DOI: 10.1016/j.fct.2021.112773
20644  Masaki Saito, Marina Hirano, Tomohiro Izumi, Yu Mori, Kentaro Ito, Yurika Saitoh, Nobuo Terada, Takeya Sato, Jun Sukegawa  Cytoskeletal Protein 4.1G Is Essential for the Primary Ciliogenesis and Osteoblast Differentiation in Bone Formation  International Journal of Molecular Sciences  2022  23:2094  PubMed ID: 35216233   DOI: 10.3390/ijms23042094
20653  Amir MS, Chiba N, Seong CH, Kusuyama J, Eiraku N, Ohnishi T, Nakamura N, Matsuguchi T.  HIF-1α plays an essential role in BMP9-mediated osteoblast differentiation through the induction of a glycolytic enzyme, PDK1.  J Cell Physiol  2022    PubMed ID: 35411937   DOI: 10.1002/jcp.30752
20696  Karakeçili A, Korpayev S, Orhan K.  Optimizing Chitosan/Collagen Type I/Nanohydroxyapatite Cross-linked Porous Scaffolds for Bone Tissue Engineering.  Appl Biochem Biotechnol  2022    PubMed ID: 35543856   DOI: 10.1007/s12010-022-03962-0
20700  Elsheikh M, Kishida R, Hayashi K, Tsuchiya A, Shimabukuro M, Ishikawa K.  Effects of pore interconnectivity on bone regeneration in carbonate apatite blocks.  Regen Biomater  2022  9(1):rbac010  PubMed ID: 35449826   DOI: 10.1093/rb/rbac010
20715  Kondo T, Chiba T, Tousen Y.  Short-chain fatty acids, acetate and propionate, directly upregulate osteoblastic differentiation.  Int J Food Sci Nutr  2022  1-9  PubMed ID: 35616294   DOI: 10.1080/09637486.2022.2078285
16506  Sasaki Y, Nakatsuka R, Inouchi T, Masutani M, Nozaki T.  Inhibition of Poly (ADP-Ribose) Glycohydrolase Accelerates Osteoblast Differentiation in Preosteoblastic MC3T3-E1 Cells  Int J Mol Sci  2022  23(9):5041  PubMed ID: 35563432   DOI: 10.3390/ijms23095041
20721  Taga Y, Iwasaki Y, Tometsuka C, Funato N, Shigemura Y, Kusubata M, Mizuno K.  Identification of a highly stable bioactive 3-hydroxyproline-containing tripeptide in human blood after collagen hydrolysate ingestion.  NPJ Sci Food  2022  6(1):29  PubMed ID: 35662250   DOI: 10.1038/s41538-022-00144-4
16744  Yamashita S, Katsumi H, Sakane T, Yamamoto A.  Phosphorylated Serine-Modified Polyamidoamine Dendrimer as an Osteoid Surface-Targeting Drug Carrier  Mol Pharm  2022  19(7):2573-2582  PubMed ID: 35666687   DOI: 10.1021/acs.molpharmaceut.2c00271
16923  Yuan H, Ikegame M, Fukuhara Y, Takemoto F, Yu Y, Teramachi J, Weng Y, Guo J, Yamada D, Takarada T, Li Y, Okamura H, Zhang B.  Vestigial-Like 3 Plays an Important Role in Osteoblast Differentiation by Regulating the Expression of Osteogenic Transcription Factors and BMP Signaling  Calcif Tissue Int  2022  Jun 24  PubMed ID: 35750933   DOI: 10.1007/s00223-022-00997-7
20849  Coşkun S, Akbulut SO, Sarıkaya B, Çakmak S, Gümüşderelioğlu M.  Formulation of chitosan and chitosan-nanoHAp bioinks and investigation of printability with optimized bioprinting parameters.  Int J Biol Macromol  2022    PubMed ID: 36113600   DOI: 10.1016/j.ijbiomac.2022.09.078
20876  Takeyama H, Maruta M, Sato T, Kajimoto N, Fujii E, Matsuura T, Tsuru K.  Fabrication of bioresorbable hydroxyapatite bone grafts through the setting reaction of calcium phosphate cement.  Dent Mater J  2022    PubMed ID: 36002294   DOI: 10.4012/dmj.2022-045
20888  Kurita T, Li X, Bhawal UK.  Crosstalk between microRNA-21-5p and the transcription factor Dec1 maintains osteoblast function.  Biochem Biophys Res Commun  2022  632:32-39  PubMed ID: 36194917   DOI: 10.1016/j.bbrc.2022.09.090
20969  Sugimoto H, Fukuda S, Yokawa S, Hori M, Ninomiya H, Sato T, Miyazawa K, Kawai T, Furuno T, Inouye S, Goto S, Suzuki T.  Visualization of osteocalcin and bone morphogenetic protein 2 (BMP2) secretion from osteoblastic cells by bioluminescence imaging.  Biochem Biophys Res Commun  2022  635:203-209  PubMed ID: 36279682   DOI: 10.1016/j.bbrc.2022.10.042
20974  Migita S, Wakabayashi K.  Analysis of disordered abrasive scratches on titanium surfaces and their impact on nuclear translocation of yes-associated protein.  Sci Rep  2022  12(1):21705  PubMed ID: 36522392   DOI: 10.1038/s41598-022-26203-0
20982  Koike T, Mikami T, Tamura JI, Kitagawa H.  Altered sulfation status of FAM20C-dependent chondroitin sulfate is associated with osteosclerotic bone dysplasia.  Nat Commun  2022  13(1):7952  PubMed ID: 36572689   DOI: 10.1038/s41467-022-35687-3
21005  Marques-Almeida T, Correia V, Fernández Martín E, García Díez A, Ribeiro C, Lanceros-Mendez S.  Piezoelectric and Magnetically Responsive Biodegradable Composites with Tailored Porous Morphology for Biotechnological Applications.  ACS Appl Polym Mater  2022  4(12):8750-8763  PubMed ID: 36570789   DOI: 10.1021/acsapm.2c01114
17412  Wang J, Noguchi S, Takizawa T, Negishi Y, Morita R, Luo SS, Takizawa T.  Placenta-specific lncRNA 1600012P17Rik is expressed in spongiotrophoblast and glycogen trophoblast cells of mouse placenta  Histochem Cell Biol  2022  158(1):65-78  PubMed ID: 35486179   DOI: 10.1007/s00418-022-02109-w
21048  Kitaura Y, Nakamura U, Awada C, Yamaguchi M, Kim M, Ikeda Y, Matsuo Y, Moriishi T, Sawase T, Chung UI, Hojo H, Ohba S.  Orally administrable peptides derived from egg yolk promote skeletal repair and ameliorate degenerative skeletal disorders in mouse models.  Regen Ther  2022  21:584-595  PubMed ID: 36475024   DOI: 10.1016/j.reth.2022.11.002
17431  Nagashima D, Ishibashi Y, Kawaguchi S, Furukawa M, Toho M, Ohno M, Nitto T, Izumo N.  Human Recombinant Lactoferrin Promotes Differentiation and Calcification on MC3T3-E1 Cells  Pharmaceutics  2022  15(1):60  PubMed ID: 36678689   DOI: 10.3390/pharmaceutics15010060
17422  Nakai H, Inokoshi M, Nozaki K, Yoshihara K, Matsukawa A, Nagaoka N, Tonprasong W, Minakuchi S.  Osteoblast Response of Additively Manufactured Zirconia and Alumina-Toughened Zirconia  Materials (Basel)  2022  15(23):8685  PubMed ID: 36500180   DOI: 10.3390/ma15238685
17423  Miyazaki S, Funamoto T, Sekimoto T, Kurogi S, Ohta T, Nagai T, Tajima T, Imasaka M, Yoshinobu K, Araki K, Araki M, Choijookhuu N, Hishikawa Y, Chosa E.  EPLINβ Is Involved in the Assembly of Cadherin-catenin Complexes in Osteoblasts and Affects Bone Formation  Acta Histochem Cytochem  2022  55(3):99-11  PubMed ID: 35821749   DOI: 10.1267/ahc.22-00027
17424  Thira Rojasawasthien, Michihiko Usui, William N. Addison, Takuma Matsubara, Tomohiko Shirakawa, Toshiyuki Tsujisawa, Keisuke Nakashima, Shoichiro Kokabu  Nobiletin, a NF‐κB signaling antagonist, promotes BMP ‐induced bone formation  FASEB BioAdvances  2022      DOI: 10.1096/fba.2022-00093
17425  Silva CA, Fernandes MM, Ribeiro C, Lanceros-Mendez S.  Two- and three-dimensional piezoelectric scaffolds for bone tissue engineering  Colloids Surf B Biointerfaces  2022  218:112708  PubMed ID: 35985127   DOI: 10.1016/j.colsurfb.2022.112708
17426  Karakeçili A, Topuz B, Ersoy FŞ, Şahin T, Günyakti A, Demirtaş TT.  UiO-66 metal-organic framework as a double actor in chitosan scaffolds: Antibiotic carrier and osteogenesis promoter  Biomater Adv  2022  136:212757  PubMed ID: 35929303   DOI: 10.1016/j.bioadv.2022.212757
17427  Ishihata K, Seong CH, Kibe T, Nakazono K, Mardiyantoro F, Tada R, Nishimura M, Matsuguchi T, Nakamura N.  Lipoteichoic Acid and Lipopolysaccharides Are Affected by p38 and Inflammatory Markers and Modulate Their Promoting and Inhibitory Effects on Osteogenic Differentiation  Int J Mol Sci  2022  23(20):1263  PubMed ID: 36293485   DOI: 10.3390/ijms232012633
17428  Bo-Young Kim, Do-Wan Kim, Eunkuk Park, Jeonghyun Kim, Chang-Gun Lee, Hyun-Seok Jin, Seon-Yong Jeong  Identification of novel susceptibility genes associated with bone density and osteoporosis in Korean women  Journal of Genetic Medicine  2022  19:63-75    DOI: 10.5734/jgm.2022.19.2.63
17429  Sungho Lee, Yoshihiko Sugimoto, Katsuya Kato, Tatsuya Miyajima, Makoto Sakurai, Fukue Nagata  Development of beta-carotene-loaded poly(lactic acid)/hydroxyapatite core-shell nanoparticles for osteoblast differentiation  Journal of Asian Ceramic Societies  2022  10:744-754    DOI: 10.1080/21870764.2022.2127262
17430  Tsuji K, Kimura S, Tateda K, Takahashi H.  Protective effect of teriparatide against vancomycin-induced cytotoxicity in osteoblasts  J Orthop Sci  2022  S0949-2658(22)00293-7.  PubMed ID: 36371341   DOI: 10.1016/j.jos.2022.09.018
17434  Fernandes MM, Carvalho EO, Correia DM, Esperança JMSS, Padrão J, Ivanova K, Hoyo J, Tzanov T, Lanceros-Mendez S.  Ionic Liquids as Biocompatible Antibacterial Agents: A Case Study on Structure-Related Bioactivity on Escherichia coli  ACS Appl Bio Mater  2022  5(11):5181-5189  PubMed ID: 36260814   DOI: 10.1021/acsabm.2c00615
17436  Watanabe M, Yahagi T, Shirayama T, Miyake K, Kotani H, Ogawa T, Matsuzaki K.  Effects of a Whole Plant Extract of Scutellaria rubropunctata var. rubropunctata on Bone Metabolism with Estrogen Receptor Activation  Plants (Basel)  2022  11(16):2075  PubMed ID: 36015379   DOI: 10.3390/plants11162075
17437  Shimura T, Shiga R, Sasatani M, Kamiya K, Ushiyama A.  Melatonin and MitoEbselen-2 Are Radioprotective Agents to Mitochondria  Genes (Basel)   2022  14(1):45  PubMed ID: 36672786   DOI: 10.3390/genes14010045
13248  Nishida E, Miyaji H, Shitomi K, Sugaya T, Akasaka T.  Evaluation of antibacterial and cytocompatible properties of multiple-ion releasing zinc-fluoride glass nanoparticles.  Dent Mater J  2021  40(1):157-164  PubMed ID: 32999216   DOI: 10.4012/dmj.2019-176
13407  Oka S, Li X, Zhang F, Tewari N, Ma R, Zhong L, Makishima M, Liu Y, Bhawal UK.  MicroRNA-21 facilitates osteoblast activity.  Biochem Biophys Rep  2021    PubMed ID: 33426313   DOI: 10.1016/j.bbrep.2020.100894
20047  Miyama A, Ebina K, Hirao M, Okamura G, Etani Y, Takami K, Goshima A, Miura T, Oyama S, Kanamoto T, Yoshikawa H, Nakata K.  Effects of iguratimod on glucocorticoid-induced disorder of bone metabolism in vitro.  J Bone Miner Metab  2021    PubMed ID: 33564917   DOI: 10.1007/s00774-021-01206-5
20056  Rojasawasthien T, Shirakawa T, Washio A, Tsujisawa T, Matsubara T, Inoue A, Takahama U, Nakashima K, Kokabu S.  Vignacyanidin Polyphenols Isolated from Vigna Angularis Bean Promote Osteoblast Differentiation.  In Vivo  2021  35(2):883-888  PubMed ID: 33622880   DOI: 10.21873/invivo.12328
13561  Seong CH, Chiba N, Kusuyama J, Subhan Amir M, Eiraku N, Yamashita S, Ohnishi T, Nakamura N, Matsuguchi T.  Bone morphogenetic protein 9 (BMP9) directly induces Notch effector molecule Hes1 through the SMAD signaling pathway in osteoblasts  FEBS Lett  2021  595(3):389-403  PubMed ID: 33264418   DOI: 10.1002/1873-3468.14016
20063  Nakamura K, Minamikawa H, Takahashi S, Yoshimura Y, Yawaka Y.  N-acetylcysteine attenuates PGE2 and ROS production stimulated by 4-META/MMA-based resin in murine osteoblastic cells.  Dent Mater J  2021    PubMed ID: 33642448   DOI: 10.4012/dmj.2020-275
20072  Kodama K, Valanezhad A, Khodaei M, Safaee S, Jafarnia S, Nesabi M, Abe S, Watanabe I, Murata H.  A novel coating layer on zirconia using modified zinc phosphatizing method.  Dent Mater J  2021    PubMed ID: 33692225   DOI: 10.4012/dmj.2020-253
13856  Kim J, Adachi T.  Modulation of Sost Gene Expression Under Hypoxia in Three-Dimensional Scaffold-Free Osteocytic Tissue  Tissue Eng Part A   2021  ;27(15-16):1037-1043  PubMed ID: 33040693   DOI: 10.1089/ten.TEA.2020.0228
14293  Shinji S, Umezawa K, Nihashi Y, Nakamura S, Shimosato T, Takaya T.  Identification of the Myogenetic Oligodeoxynucleotides (myoDNs) That Promote Differentiation of Skeletal Muscle Myoblasts by Targeting Nucleolin  Front Cell Dev Biol  2021  8:616706  PubMed ID: 33585451   DOI: 10.3389/fcell.2020.616706
20259  Chujo K, Jo JI, Tabata Y.  Intracellular controlled release prolongs the time period of siRNA-based gene suppression.  J Biomater Sci Polym Ed  2021  1-13  PubMed ID: 34348600   DOI: 10.1080/09205063.2021.1958183
15278  Masanori Horie, Sakiko Sugino, Atsumi Tada, Kazuhiro Nara  Groundnut (Apios americana Medik) Extract Enhances the Osteoblast Differentiation of MC3T3-E1 Cells  Natural Product Communications  2021  16:1934578X2110105    DOI: 10.1177/1934578x211010567
20337  Kim J, Kigami H, Adachi T.  Comparative gene expression analysis for pre-osteoblast MC3T3-E1 cells under non-adhesive culture toward osteocyte differentiation.  J Biosci Bioeng  2021    PubMed ID: 34556421   DOI: 10.1016/j.jbiosc.2021.09.004
15495  Shiva Jafarnia, Alireza Valanezhad, Shigeaki Abe, Sima Shahabi, Ikuya Watanabe  Resin-based sealant containing sol–gel derived bioactive glass: ion release and biological response  Journal of Sol-Gel Science and Technology  2021      DOI: 10.1007/s10971-021-05551-9
15498  Ge G, Yang S, Hou Z, Gan M, Tao H, Zhang W, Li W, Wang Z, Hao Y, Gu Y, Geng D.  Theaflavin-3,3'-Digallate Promotes the Formation of Osteoblasts Under Inflammatory Environment and Increases the Bone Mass of Ovariectomized Mice  Front Pharmacol  2021  12:648969  PubMed ID: 33833684   DOI: 10.3389/fphar.2021.648969
15528  Izumiya M, Haniu M, Ueda K, Ishida H, Ma C, Ideta H, Sobajima A, Ueshiba K, Uemura T, Saito N, Haniu H.  Evaluation of MC3T3-E1 Cell Osteogenesis in Different Cell Culture Media  Int J Mol Sci  2021  22(14):7752  PubMed ID: 34299372   DOI: 10.3390/ijms22147752
20489  Kaga N, Fujimoto H, Morita S, Yamaguchi Y, Matsuura T.  Contact Angle and Cell Adhesion of Micro/Nano-Structured Poly(lactic-co-glycolic acid) Membranes for Dental Regenerative Therapy.  Dent J (Basel)  2021  9(11)  PubMed ID: 34821588   DOI: 10.3390/dj9110124
16039  Yasser Abdelrhman, Sengo Kobayashi, Satoshi Okano, Takeaki Okamoto, Mohamed Abdel-Hady Gepreel  Biocompatibility of Anodized Low-Cost Ti-4.7Mo-4.5Fe Alloy  Materials Science Forum  2021  1016:458-464    DOI: 10.4028/
16043  Nguyen Xuan Thanh Tram, Kunio Ishikawa3, Tran Hoang Minh, David Benson and Kanji Tsuru  Characterization of carbonate apatite derived from chicken bone and its in-vitro evaluation using MC3T3-E1 cells  Mater. Res. Express 8 025401  2021  8:025401   
16044  Masanobu KAMITAKAHARA, Airi ISHII, Hideaki MATSUBARA, Masakazu KAWASHITA, Maiko FURUYA, Hiroyasu KANETAKA  Fabrication and evaluation of ascorbic acid phosphate-loaded spherical porous hydroxyapatite/octacalcium phosphate granules  Journal of the Ceramic Society of Japan  2021  129:60-65    DOI: 10.2109/jcersj2.20170
16054  Murakami T, Matsugami D, Yoshida W, Imamura K, Bizenjima T, Seshima F, Saito A.  Healing of Experimental Periodontal Defects Following Treatment with Fibroblast Growth Factor-2 and Deproteinized Bovine Bone Mineral  Biomolecules  2021  11(6):805  PubMed ID: 34072351   DOI: 10.3390/biom11060805
16274  Aonuma F, Higashi S, Tsuka S, Ohsumi T, Masaki C, Hosokawa R, Takeuchi H.  Effect of aging on bone metabolism: the involvement of complement C1q  J Prosthodont Res  2021  65(3):393-399  PubMed ID: 33116027   DOI: 10.2186/jpr.JPOR_2019_644
16328  Almeida Alves CF, Fialho L, Marques SM, Pires S, Rico P, Palacio C, Carvalho S.  MC3T3-E1 cell response to microporous tantalum oxide surfaces enriched with Ca, P and Mg  Mater Sci Eng C Mater Biol Appl  2021  112008  PubMed ID: 33947579   DOI: 10.1016/j.msec.2021.112008
16329  Valanezhad A, Odatsu T, Abe S, Watanabe I.  Bone Formation Ability and Cell Viability Enhancement of MC3T3-E1 Cells by Ferrostatin-1 a Ferroptosis Inhibitor of Cancer Cells  Int J Mol Sci  2021  22(22):12259  PubMed ID: 34830144   DOI: 10.3390/ijms222212259
16330  Ryoichi Sato, Yasuhiro Namura, Natsuko Tanabe, Mayu Sakai, Akihisa Utsu, Keiko Tomita, Naoto Suzuki, Mitsuru Motoyoshi  Atmospheric Pressure Plasma Treatment with Nitrogen Induces Osteoblast Differentiation and Reduces iNOS and COX-2 Expressions  Journal of Hard Tissue Biology  2021  30:131-136    DOI: 10.2485/jhtb.30.131
16331  Lee CG, Kim J, Yun SH, Hwang S, Jeon H, Park E, Jeong SY.  Anti-Osteoporotic Effect of Morroniside on Osteoblast and Osteoclast Differentiation In Vitro and Ovariectomized Mice In Vivo  Int J Mol Sci  2021  ;22(19):10642  PubMed ID: 34638983   DOI: 10.3390/ijms221910642
16333  Jarrar H, Çetin Altındal D, Gümüşderelioğlu M.  Scaffold-based osteogenic dual delivery system with melatonin and BMP-2 releasing PLGA microparticles  Int J Pharm  2021  600:120489  PubMed ID: 33744449   DOI: 10.1016/j.ijpharm.2021.120489
16334  Nishino K, Tamai K, Orita K, Hashimoto Y, Nakamura H.  Heated Tobacco Products Impair Cell Viability, Osteoblastic Differentiation, and Bone Fracture-Healing  J Bone Joint Surg Am  2021  103(21):2024-2031  PubMed ID: 34730563   DOI: 10.2106/JBJS.20.02227
16335  Pham DN, Hiromoto S, Yamazaki T, O M, Kobayashi E.  Enhanced Corrosion Resistance and In Vitro Biocompatibility of Mg-Zn Alloys by Carbonate Apatite Coating  ACS Appl Bio Mater  2021  4(9):6881-6892  PubMed ID: 35006988   DOI: 10.1021/acsabm.1c00594
16336  Safaee S, Valanezhad A, Nesabi M, Jafarnia S, Sano H, Shahabi S, Abe S, Watanabe I.  Fabrication of bioactive glass coating on pure titanium by sol-dip method: Dental applications  Dent Mater J  2021  40:949-956  PubMed ID: 33716277   DOI: 10.4012/dmj.2020-323
16337  Soner Cakmak  Compressible polyglycolic acid-based nanofibrous matrices as a bone filler: fabrication, physicochemical characterisations, and biocompatibility evaluation  Materials Technology  2021  1-12    DOI: 10.1080/10667857.2021.1959216
16339  Kazuhiro Saito, Masanori Hiratuka, Yoshinobu Manome, Kouki Fujioka, Yasuharu Ohgoe, Hiroshi Honda, Kenji Hirakuri  Effects of zinc-containing diamond-like carbon coated splints on the healing of fractures in mice: A pilot study  Diamond and Related Materials  2021  119:108574    DOI: 10.1016/j.diamond.2021.108574
16340  Raihan MM, Otsuka Y, Tsuchida K, Manonukul A, Ohnuma K, Miyashita Y.  Damage evaluation of HAp-coated porous titanium foam in simulated body fluid based on compression fatigue behavior  J Mech Behav Biomed Mater  2021  117:104383  PubMed ID: 33596530   DOI: 10.1016/j.jmbbm.2021.104383
16362  Fujimaki T, Ando T, Hata T, Takayama Y, Ohba T, Ichikawa J, Takiyama Y, Tatsuno R, Koyama K, Haro H.  Exogenous parathyroid hormone attenuates ovariectomy-induced skeletal muscle weakness in vivo  Bone  2021  151:116029.  PubMed ID: 34111645   DOI: 10.1016/j.bone.2021.116029
16379  Katsuya SATO, Daiki OOMORI  Development of vibration mechanical stimuli loading device for live cell fluorescence microscopy  Journal of Biomechanical Science and Engineering  2021      DOI: 10.1299/jbse.21-00294
16382  Wandel MB, Bell CA, Yu J, Arno MC, Dreger NZ, Hsu YH, Pitto-Barry A, Worch JC, Dove AP, Becker ML.  Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering  Nat Commun  2021  12(1):446  PubMed ID: 33469013   DOI: 10.1038/s41467-020-20610-5
16383  Yamazaki M, Kawai M, Kinoshita S, Tachikawa K, Nakanishi T, Ozono K, Michigami T.  Clonal osteoblastic cell lines with CRISPR/Cas9-mediated ablation of Pit1 or Pit2 show enhanced mineralization despite reduced osteogenic gene expression  Bone  2021  151:116036  PubMed ID: 34118444   DOI: 10.1016/j.bone.2021.116036
16868  Xiang C, Tenkumo T, Ogawa T, Kanda Y, Nakamura K, Shirato M, Sokolova V, Epple M, Kamano Y, Egusa H, Sasaki K.  Gene transfection achieved by utilizing antibacterial calcium phosphate nanoparticles for enhanced regenerative therapy  Acta Biomater  2021  119:375-389  PubMed ID: 33166711   DOI: 10.1016/j.actbio.2020.11.003
16878  Shuhei Ugaji, Kumi Kimura, Yasuhiko Yamamoto, Seiichi Munesue, Ai Harashima, Takao Aikawa, Yasuhisa Yoshida, Tomo Hamada, Toshifumi Hikichi, Hidenori Matsubara, Hiroyuki Tsuchiya  Pyridoxamine improves diabetes-evoked delayed bone repair in mice  Journal of Translational Science  2021  7    DOI: 10.15761/jts.1000413
16970  Miho Tamai, Kenichi Harimoto, Noriyuki Nagaoka, Kumiko Yoshihara, Yasuhiro Yoshida, Yoh-ichi Tagawa  Cell Adherence Competition between Osteoblasts and Fibroblasts on Various Materials Influences the Establishment of Osseointegration  Archives of Clinical and Biomedical Research  2021  05    DOI: 10.26502/acbr.50170191
17414  Saito M, Chiba A, Sato T, Moriya T, Sukegawa J, Nakahata N.  Tctex-1 augments G protein-coupled receptor-mediated Gs signaling by activating adenylyl cyclase  J Pharmacol Sci  2021  145(1):150-154  PubMed ID: 33357773   DOI: 10.1016/j.jphs.2020.11.011
17415  Yamaguchi Y, Matsuno T, Miyazawa A, Hashimoto Y, Satomi T.  Bioactivity Evaluation of Biphasic Hydroxyapatite Bone Substitutes Immersed and Grown with Supersaturated Calcium Phosphate Solution  Materials (Basel)  2021  14(18):5143  PubMed ID: 34576367   DOI: 10.3390/ma14185143
17416  Toprak Ö, Topuz B, Monsef YA, Oto Ç, Orhan K, Karakeçili A.  BMP-6 carrying metal organic framework-embedded in bioresorbable electrospun fibers for enhanced bone regeneration  Mater Sci Eng C Mater Biol Appl  2021  120:111738  PubMed ID: 33545881   DOI: 10.1016/j.msec.2020.111738
11802  Wang L, Bai J, Wang Q, Ge G, Lin J, Xu N, Xu C, Xu Y, Wang Y, Geng D.  Inhibition of protein phosphatase 2A attenuates titanium-particle induced suppression of bone formation.  Int. J. Biol. Macromol  2020  142:142-151  PubMed ID: 31521663   DOI: 10.1016/j.ijbiomac.2019.09.084
11852  Mulati M, Kobayashi Y, Takahashi A, Numata H, Saito M, Hiraoka Y, Ochi H, Sato S, Ezura Y, Yuasa M, Hirai T, Yoshii T, Okawa A, Inose H.  The long noncoding RNA Crnde regulates osteoblast proliferation through the Wnt/β-catenin signaling pathway in mice.  Bone  2020  130:115076  PubMed ID: 31622775   DOI: 10.1016/j.bone.2019.115076
6952  Minamizaki T, Nakao Y, Irie Y, Ahmed F, Itoh S, Sarmin N, Yoshioka H, Nobukiyo A, Fujimoto C, Niida S, Sotomaru Y, Tanimoto K, Kozai K, Sugiyama T, Bonnelye E, Takei Y, Yoshiko Y.  The matrix vesicle cargo miR-125b accumulates in the bone matrix, inhibiting bone resorption in mice.  Commun Biol  2020  ;3(1):30  PubMed ID: 31949279   DOI: 10.1038/s42003-020-0754-2
11934  Pimentel ES, Brito-Pereira R, Marques-Almeida T, Ribeiro C, Vaz F, Lanceros-Mendez S, Cardoso VF.  Tailoring Electrospun Poly(l-lactic acid) Nanofibers as Substrates for Microfluidic Applications.  ACS Appl Mater Interfaces  2020    PubMed ID: 31808332   DOI: 10.1021/acsami.9b12461
11946  Miyaji H, Mayumi K, Miyata S, Nishida E, Shitomi K, Hamamoto A, Tanaka S, Akasaka T.  Comparative biological assessments of endodontic root canal sealer containing surface pre-reacted glass-ionomer (S-PRG) filler or silica filler.  Dent Mater J  2020    PubMed ID: 31776316   DOI: 10.4012/dmj.2019-029
12034  Gültan T, Çapkın Yurtsever M, Gumusderelioglu M.  NaOH etched /boron- doped nanohydroxyapatite coated PEEK implants enhance the proliferation and differentiation of osteogenic cells.  Biomed Mater  2020    PubMed ID: 32000154   DOI: 10.1088/1748-605X/ab7198
12037  Nakagawa F, Higashi S, Ando E, Ohsumi T, Watanabe S, Takeuchi H.  Modification of TRPV4 activity by acetaminophen.  Heliyon  2020    PubMed ID: 32051870   DOI: 10.1016/j.heliyon.2020.e03301
12070  Suzuki A, Sugiyama G, Ohyama Y, Kumamaru W, Yamada T, Mori Y.  Regulation of NF-kB Signalling Through the PR55β-RelA Interaction in Osteoblasts.  In Vivo  2020    PubMed ID: 32111759   DOI: 10.21873/invivo.11813
12118  Shimabukuro M, Tsutsumi Y, Nozaki K, Chen P, Yamada R, Ashida M, Doi H, Nagai A, Hanawa T.  Investigation of antibacterial effect of copper introduced titanium surface by electrochemical treatment against facultative anaerobic bacteria.  Dent Mater J  2020    PubMed ID: 32249235   DOI: 10.4012/dmj.2019-178
12120  Okusha Y, Eguchi T, Tran MT, Sogawa C, Yoshida K, Itagaki M, Taha EA, Ono K, Aoyama E, Okamura H, Kozaki KI, Calderwood SK, Takigawa M, Okamoto K.  Extracellular Vesicles Enriched with Moonlighting Metalloproteinase Are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer.  Cancers (Basel)  2020    PubMed ID: 32260433   DOI: 10.3390/cancers12040881
12139  Miona Miljković, Vesna Lazić, Slađana Davidović, Ana Milivojević, Jelena Papan, Margarida M. Fernandes, Senentxu Lanceros-Mendez, S. Phillip Ahrenkiel & Jovan M. Nedeljković  Selective Antimicrobial Performance of Biosynthesized Silver Nanoparticles by Horsetail Extract Against E. coli  Journal of Inorganic and Organometallic Polymers and Materials  2020  30:2598–2607    DOI: 10.1007/s10904-019-01402-x
12140  Peng Chen, Huihong Liu, Mitsuo Niinomi, Zenji Horita, Hidetoshi Fujii, Takao Hanawa  Fatigue Property and Cytocompatibility of a Biomedical Co–Cr–Mo Alloy Subjected to a High Pressure Torsion and a Subsequent Short Time Annealing  MATERIALS TRANSACTIONS  2020      DOI: 10.2320/matertrans.MT-M2019148
12147  Satoshi Migita, Tomoya Yamaguchi  Initial Adhesion Behavior of Osteoblast on Titanium with Sub-Micron Scale Roughness  Recent Progress in Materials  2020      DOI: 10.21926/rpm.2001003
12167  Thet ThetSwe, Khairul AnuarShariff, Hasmaliza Mohamad, Kunio Ishikawa, Koichiro Hayashi, Mohamad HafiziAbu Bakar  Behavioural response of cells and bacteria on single and multiple doped Sr and Ag S53P4 sol-gel bioglass  Ceramics International  2020      DOI: 10.1016/j.ceramint.2020.04.094
13025  Furihata T, Miyaji H, Nishida E, Kato A, Miyata S, Shitomi K, Mayumi K, Kanemoto Y, Sugaya T, Akasaka T.  Bone forming ability of recombinant human collagen peptide granules applied with β-tricalcium phosphate fine particles.  J Biomed Mater Res B Appl Biomater  2020    PubMed ID: 32386261   DOI: 10.1002/jbm.b.34632
13043  Inubushi T, Kosai A, Yanagisawa S, Chanbora C, Miyauchi M, Yamasaki S, Sugiyama E, Ishikado A, Makino T, Takata T.  Bovine lactoferrin enhances osteogenesis through Smad2/3 and p38 MAPK activation.  J Oral Biosci  2020    PubMed ID: 32464258   DOI: 10.1016/j.job.2020.05.001
13070  Santhakumar S, Oyane A, Nakamura M, Koga K, Miyata S, Muratsubaki K, Miyaji H.  In situ precipitation of amorphous calcium phosphate nanoparticles within 3D porous collagen sponges for bone tissue engineering.  Mater Sci Eng C Mater Biol Appl  2020    PubMed ID: 32806285   DOI: 10.1016/j.msec.2020.111194
13094  Huang Y, Xiao D, Huang S, Zhuang J, Zheng X, Chang Y, Yin D.  Circular RNA YAP1 attenuates osteoporosis through up-regulation of YAP1 and activation of Wnt/β-catenin pathway.  Biomed Pharmacother  2020    PubMed ID: 32768931   DOI: 10.1016/j.biopha.2020.110365
13100  Rajan ST, V V AT, Terada-Nakaishi M, Chen P, Hanawa T, Nandakumar AK, Subramanian B.  Zirconium-based metallic glass and zirconia coatings to inhibit bone formation on titanium.  Biomed Mater  2020    PubMed ID: 32615545   DOI: 10.1088/1748-605X/aba23a
13107  Kito H, Morihiro H, Sakakibara Y, Endo K, Kajikuri J, Suzuki T, Ohya S.  Downregulation of the Ca2+-activated K+ channel KCa3.1 in mouse preosteoblast cells treated with vitamin D receptor agonist.  Am J Physiol Cell Physiol  2020    PubMed ID: 32520608   DOI: 10.1152/ajpcell.00587.2019
13145  Lazić V, Živković LS, Sredojević D, Fernandes MM, Lanceros-Mendez S, Ahrenkiel SP, Nedeljković JM.  Tuning Properties of Cerium Dioxide Nanoparticles by Surface Modification with Catecholate-type of Ligands.  Langmuir  2020    PubMed ID: 32787065   DOI: 10.1021/acs.langmuir.0c01163
13165  Haraguchi T, Ayukawa Y, Shibata Y, Takeshita T, Atsuta I, Ogino Y, Yasunami N, Yamashita Y, Koyano K.  Effect of Calcium Chloride Hydrothermal Treatment of Titanium on Protein, Cellular, and Bacterial Adhesion Properties.  J Clin Med  2020    PubMed ID: 32823609   DOI: 10.3390/jcm9082627
13196  Kato S, Tanabe N, Nagao M, Sekino J, Tomita K, Sakai M, Abe K, Suzuki N, Ueda K.  Glucose transporter 4 mediates LPS-induced IL-6 production in osteoblasts under high glucose conditions.  J Oral Sci  2020    PubMed ID: 32863319   DOI: 10.2334/josnusd.20-0010
13219  Sugiura Y, Obika H, Horie M, Niitsu K, Makita Y.  Aesthetic Silver-Doped Octacalcium Phosphate Powders Exhibiting Both Contact Antibacterial Ability and Low Cytotoxicity.  ACS Omega  2020    PubMed ID: 33015459   DOI: 10.1021/acsomega.0c02868
13273  Natsume N, Yonezawa T, Woo JT, Teruya T.  Effect of pinocembrin isolated from Alpinia zerumbet on osteoblast differentiation.  Cytotechnology  2020    PubMed ID: 33029744   DOI: 10.1007/s10616-020-00427-2
13343  Yamabe Y, Kawagoe Y, Okuno K, Inoue M, Chikaoka K, Ueda D, Tajima Y, Yamada TK, Kakihara Y, Hara T, Sato T.  Construction of an artificial system for ambrein biosynthesis and investigation of some biological activities of ambrein.  Sci Rep  2020    PubMed ID: 33184314   DOI: 10.1038/s41598-020-76624-y
13357  Marques-Almeida T, Cardoso VF, Gama M, Lanceros-Mendez S, Ribeiro C.  Patterned Piezoelectric Scaffolds for Osteogenic Differentiation.  Int J Mol Sci  2020    PubMed ID: 33171761   DOI: 10.3390/ijms21218352
13360  Park E, Kim J, Jin HS, Choi CW, Choi TH, Choi S, Huh D, Jeong SY.  Scopolin Attenuates Osteoporotic Bone Loss in Ovariectomized Mice.  Nutrients  2020    PubMed ID: 33233714   DOI: 10.3390/nu12113565
13378  Carvalho EO, Ribeiro C, Correia DM, Botelho G, Lanceros-Mendez S.  Biodegradable Hydrogels Loaded with Magnetically Responsive Microspheres as 2D and 3D Scaffolds.  Nanomaterials (Basel)  2020    PubMed ID: 33287454   DOI: 10.3390/nano10122421
13406  Park E, Lee CG, Lim E, Hwang S, Yun SH, Kim J, Jeong H, Yong Y, Yun SH, Choi CW, Jin HS, Jeong SY.  Osteoprotective Effects of Loganic Acid on Osteoblastic and Osteoclastic Cells and Osteoporosis-Induced Mice.  Int J Mol Sci  2020    PubMed ID: 33379387   DOI: 10.3390/ijms22010233
13435  Ayumu Takeno, Ippei Kanazawa, Ken-ichiro Tanaka, Masakazu Notsu, Keizo Kanasaki, Takamasa Oono, Yoshihiro Ogawa & Toshitsugu Sugimoto   High glucose promotes mineralization via bone morphogenetic protein 4-Smad signals in early stage of osteoblast differentiation  Diabetology International  2020      DOI: 10.1007/s13340-020-00463-5
13443  T. T. Swe, K. A. Shariff, A. F. M. Noor, K. Ishikawa, and M. Hasmaliza  Effect of strontium doping on bone nodule formation of sol-gel derived bioglass  AIP Conference Proceedings  2020      DOI: 10.1063/5.0015714
13446  Ahmed Monir, Abdel Basit Abd El-Aal, Mohamed Omar, Mahasen El-Shair, Taro Mukaibo3, Ryuji Hosokawa  The Viability and Cytotoxic Effect of High Mobility Group Box Protein 1 on MC3T3-E1 Pre-osteoblast Cells: an In Vitro Study  Zagazig Veterinary Journal  2020      DOI: 10.21608/zvjz.2020.27091.1106
13508  Tenkumo T, Ishiyama K, Prymak O, Nakamura K, Shirato M, Ogawa T, Miyashita M, Takahashi M, Epple M, Kanno T, Sasaki K.  Bactericidal activity and recovery effect of hydroxyl radicals generated by ultraviolet irradiation and silver ion application on an infected titanium surface  Sci Rep  2020  10(1):855  PubMed ID: 32444858   DOI: 10.1038/s41598-020-65411-4
13536  Amaro L, Correia DM, Martins PM, Botelho G, Carabineiro SAC, Ribeiro C, Lanceros-Mendez S.  Morphology Dependence Degradation of Electro- and Magnetoactive Poly(3-hydroxybutyrate-co-hydroxyvalerate) for Tissue Engineering Applications  Polymers (Basel)  2020  12(4):953  PubMed ID: 32325963   DOI: 10.3390/polym12040953
13546  Wang Q, Ge G, Liang X, Bai J, Wang W, Zhang W, Zheng K, Yang S, Wei M, Yang H, Xu Y, Liu B, Geng D.  Punicalagin ameliorates wear-particle-induced inflammatory bone destruction by bi-directional regulation of osteoblastic formation and osteoclastic resorption  Biomater Sci  2020  8(18):5157-5171  PubMed ID: 32840273   DOI: 10.1039/d0bm00718h
13636  Inoue A, Nakao-Kuroishi K, Kometani-Gunjigake K, Mizuhara M, Shirakawa T, Ito-Sago M, Yasuda K, Nakatomi M, Matsubara T, Tada-Shigeyama Y, Morikawa K, Kokabu S, Kawamoto T.  VNUT/SLC17A9, a vesicular nucleotide transporter, regulates osteoblast differentiation  FEBS Open Bio  2020  10(8):1612-1623.  PubMed ID: 32592329   DOI: 10.1002/2211-5463.12918
13638  Yamada S, Motozuka S, Tagaya M.  Synthesis of nanostructured silica/hydroxyapatite hybrid particles containing amphiphilic triblock copolymer for effectively controlling hydration layer structures with cytocompatibility  J Mater Chem B7.  2020  8(7):1524-153  PubMed ID: 32003398   DOI: 10.1039/c9tb02534k
13649  Suzuki R, Fujiwara Y, Saito M, Arakawa S, Shirakawa JI, Yamanaka M, Komohara Y, Marumo K, Nagai R.  Intracellular Accumulation of Advanced Glycation End Products Induces Osteoblast Apoptosis Via Endoplasmic Reticulum Stress  J Bone Miner Res  2020  35(10):1992-2003  PubMed ID: 32427355   DOI: 10.1002/jbmr.4053
13839  Kako Yamasaki, Mitsuhiro Hirano, Shiori komai, Hiroki Taniho, Naofumi Ohtsu  Cell responses on Ni-free anodized layer of NiTi alloy with various surface morphologies  Applied Surface Science  2020  531:30    DOI: 10.1016/j.apsusc.2020.147351
13923  Raju R, Oshima M, Inoue M, Morita T, Huijiao Y, Waskitho A, Baba O, Inoue M, Matsuka Y.  Three-dimensional periodontal tissue regeneration using a bone-ligament complex cell sheet  Sci Rep  2020  10(1):1656  PubMed ID: 32015383   DOI: 10.1038/s41598-020-58222-0
13933  Suzuki H, Ohshima N, Tatei K, Taniguchi T, Sato S, Izumi T.  The role of autonomously secreted PGE 2 and its autocrine/paracrine effect on bone matrix mineralization at the different stages of differentiating MC3T3-E1 cells  Biochem Biophys Res Commun  2020  524(4):929-935  PubMed ID: 32059846   DOI: 10.1016/j.bbrc.2020.01.120
13938  Widyowati, Retno; Ekasari, Wiwied; Purwitasari, Neny  Amine Derivative from the Aerial Part of Spilanthes acmella Murr. and their Alkaline Phosphatase Activity  The Natural Products Journal  2020  10:571-577    DOI: 10.2174/2210315509666190807161413
13943  Yashiro M, Ohya M, Mima T, Nakashima Y, Kawakami K, Yamamoto S, Kobayashi S, Yano T, Tanaka Y, Sonou T, Tatsuta K, Negi S, Shigematsu T.  Active vitamin D and vitamin D analogs stimulate fibroblast growth factor 23 production in osteocyte-like cells via the vitamin D receptor  J Pharm Biomed Anal  2020  182:113139  PubMed ID: 32045827   DOI: 10.1016/j.jpba.2020.113139
14181  Tsubaki M, Seki S, Takeda T, Chihara A, Arai Y, Morii Y, Imano M, Satou T, Shimomura K, Nishida S.  The HGF/Met/NF-κB Pathway Regulates RANKL Expression in Osteoblasts and Bone Marrow Stromal Cells  Int J Mol Sci  2020  21(21):7905  PubMed ID: 33114380   DOI: 10.3390/ijms21217905
14278  Castro N, Fernandes MM, Ribeiro C, Correia V, Minguez R, Lanceros-Méndez S.  Magnetic Bioreactor for Magneto-, Mechano- and Electroactive Tissue Engineering Strategies  Sensors (Basel)   2020  20(12):3340  PubMed ID: 32545551   DOI: 10.3390/s20123340
14502  Guo J, Wang Z, Weng Y, Yuan H, Yoshida K, Ikegame M, Uchibe K, Kamioka H, Ochiai K, Okamura H, Qiu L.  N-(3-oxododecanoyl)-homoserine lactone regulates osteoblast apoptosis and differentiation by mediating intracellular calcium  Cell Signal   2020  75:109740  PubMed ID: 32818672   DOI: 10.1016/j.cellsig.2020.109740
14845  Rui Shi, Koichiro Hayashi, Kunio Ishikawa  Rapid Osseointegration Bestowed by Carbonate Apatite Coating of Rough Titanium  Advanced Materials Interfaces  2020  7:2000636    DOI: 10.1002/admi.202000636
14870  A. Reizabal, R. Brito-Pereira, M.M. Fernandes, N. Castro, V. Correia, C. Ribeiro, C.M. Costa, L. Perez, J.L. Vilas, S. Lanceros-Méndez  Silk fibroin magnetoactive nanocomposite films and membranes for dynamic bone tissue engineering strategies  Materialia  2020  12:100709    DOI: 10.1016/j.mtla.2020.100709
16376  Natsume N, Ozaki K, Nakajima D, Yokoshima S, Teruya T.  Structure-Activity Relationship Study of Majusculamides A and B and Their Analogues on Osteogenic Activity  J Nat Prod  2020  83(8):2477-2482  PubMed ID: 32786886   DOI: 10.1021/acs.jnatprod.0c00441
16377  Burger D, Beaumont M, Rosenau T, Tamada Y.  Porous Silk Fibroin/Cellulose Hydrogels for Bone Tissue Engineering via a Novel Combined Process Based on Sequential Regeneration and Porogen Leaching  Molecules  2020  25(21):5097  PubMed ID: 33153040   DOI: 10.3390/molecules25215097
16378  Daisuke Isaji, Takehiro Watanabe, Takahiro Takahashi, Hiroki Sato, Hiroshi Nakada, Yasuhiro Tanimoto, Megumi Fuse, Suguru Kimoto, Yasuhiko Kawai  Examination of Optimal Concentrations of Poly (Lactic-co-glycolic Acid) in Hexafluoroisopropyl Alcohol for Guided Bone Regeneration Membrane Prepared by Electrospinning  International Journal of Oral-Medical Sciences  2020  18:239-247    DOI: 10.5466/ijoms.18.239
16380  Tsuji K, Kimura S, Tateda K, Takahashi H.  Does Vitamin D3 Prevent the Inhibitory Effect of Vancomycin on Osteoblasts?  Clin Orthop Relat Res  2020  478(2):420-433  PubMed ID: 31794484   DOI: 10.1097/CORR.0000000000001060
16381  Daisuke Isaji, Takehiro Watanabe, Takahiro Takahashi, Hiroki Sato, Hiroshi Nakada, Yasuhiro Tanimoto, Megumi Fuse, Suguru Kimoto, Yasuhiko Kawai  Preparation and Evaluation of a Poly(Lactic-co-glycolic Acid)Membrane Containing β-TCP  International Journal of Oral-Medical Sciences  2020  18:248-256    DOI: 10.5466/ijoms.18.248
16930  Miki H, Okito A, Akiyama M, Ono T, Tachikawa N, Nakahama KI.  Genetic and epigenetic regulation of osteopontin by cyclic adenosine 3' 5'-monophosphate in osteoblasts  Gene  2020  763:145059  PubMed ID: 32858177   DOI: 10.1016/j.gene.2020.145059
11232  Tsukune N, Naito M, Ohashi A, Ninomiya T, Sato S, Takahashi T.  Forced expression of mouse progerin attenuates the osteoblast differentiation interrupting β-catenin signal pathway in vitro.  Cell Tissue Res.  2019    PubMed ID: 30284086   DOI: 10.1007/s00441-018-2930-y
11258  Nguyen HT, Ono M, Oida Y, Hara ES, Komori T, Akiyama K, Nguyen HTT, Aung KT, Pham HT, Tosa I, Takarada T, Matsuo K, Mizoguchi T, Oohashi T, Kuboki T.  Bone Marrow Cells Inhibit BMP-2-Induced Osteoblast Activity in the Marrow Environment.  J. Bone Miner. Res.  2019    PubMed ID: 30352125   DOI: 10.1002/jbmr.3598
11302  Baba TT, Terashima T, Oida S.  Liver-type of tissue non-specific alkaline phosphatase is induced during mouse bone and tooth cell differentiation.  Arch. Oral Biol.  2019    PubMed ID: 30439569   DOI: 10.1016/j.archoralbio.2018.10.036
11486  Abdelrhman Y, Gepreel MA, Kobayashi S, Okano S, Okamoto T.  Biocompatibility of new low-cost (α + β)-type Ti-Mo-Fe alloys for long-term implantation.  Mater Sci Eng C Mater Biol Appl  2019    PubMed ID: 30889729   DOI: 10.1016/j.msec.2019.01.133
11445  Kuriya K, Nishio M, Wada S, Katsuzaki H, Nishise M, Okamoto H, Umekawa H.  Antiosteoporotic Effects of Acer palmatum Extract on Osteoclastogenesis and Osteoblastogenesis.  J Med Food  2019    PubMed ID: 30785809   DOI: 10.1089/jmf.2018.4243
11462  Sasaki JI, Kiba W, Abe GL, Katata C, Hashimoto M, Kitagawa H, Imazato S.  Fabrication of strontium-releasable inorganic cement by incorporation of bioactive glass.  Dent Mater  2019    PubMed ID: 30827799   DOI: 10.1016/
11484  Kusuyama J, Amir MS, Albertson BG, Bandow K, Ohnishi T, Nakamura T, Noguchi K, Shima K, Semba I, Matsuguchi T.  JNK inactivation suppresses osteogenic differentiation, but robustly induces osteopontin expression in osteoblasts through the induction of inhibitor of DNA binding 4 (Id4).  FASEB J.  2019    PubMed ID: 30884976   DOI: 10.1096/fj.201802465R
11485  Nakamura K, Shirato M, Tenkumo T, Kanno T, Westerlund A, Örtengren U, Sasaki K, Niwano Y.  Hydroxyl radicals generated by hydrogen peroxide photolysis recondition biofilm-contaminated titanium surfaces for subsequent osteoblastic cell proliferation.  Sci Rep  2019    PubMed ID: 30886168   DOI: 10.1038/s41598-019-41126-z
4575  Park E, Kim J, Kim MC, Yeo S, Kim J, Park S, Jo M, Choi CW, Jin HS, Lee SW, Li WY, Lee JW, Park JH, Huh D, Jeong SY.  Anti-Osteoporotic Effects of Kukoamine B Isolated from Lycii Radicis Cortex Extract on Osteoblast and Osteoclast Cells and Ovariectomized Osteoporosis Model Mice.  Int J Mol Sci  2019  20(11). pii: E2784  PubMed ID: 31174394   DOI: 10.3390/ijms20112784
11495  Tanaka K, Kondo H, Hamamura K, Togari A.  Systemic administration of low-dose naltrexone increases bone mass due to blockade of opioid growth factor receptor signaling in mice osteoblasts.  Life Sci.  2019    PubMed ID: 30930116   DOI: 10.1016/j.lfs.2019.03.069
11535  Suzuki H, Tatei K, Ohshima N, Sato S, Izumi T.  Regulation of MC3T3-E1 differentiation by actin cytoskeleton through lipid mediators reflecting the cell differentiation stage.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 31047639   DOI: 10.1016/j.bbrc.2019.04.093
11543  Oki Y, Kirita K, Ohta S, Ohba S, Horiguchi I, Sakai Y, Ito T.  Switching of Cell Proliferation/Differentiation in Thiol-Maleimide Clickable Microcapsules Triggered by in Situ Conjugation of Biomimetic Peptides.  Biomacromolecules  2019    PubMed ID: 31059241   DOI: 10.1021/acs.biomac.9b00333
11562  Akatsu Y, Takahashi N, Yoshimatsu Y, Kimuro S, Muramatsu T, Katsura A, Maishi N, Suzuki HI, Inazawa J, Hida K, Miyazono K, Watabe T.  Fibroblast growth factor signals regulate transforming growth factor-β-induced endothelial-to-myofibroblast transition of tumor endothelial cells via Elk1.  Mol Oncol  2019    PubMed ID: 31094056   DOI: 10.1002/1878-0261.12504
11599  Yamada M, Valanezhad A, Egoshi T, Tashima Y, Watanabe I, Murata H.  Bioactive glass coating on zirconia by vacuum sol-dipping method.  Dent Mater J  2019    PubMed ID: 31189794   DOI: 10.4012/dmj.2018-222
11601  Hermenegildo B, Ribeiro C, Pérez-Álvarez L, Vilas JL, Learmonth DA, Sousa RA, Martins P, Lanceros-Méndez S.  Hydrogel-based magnetoelectric microenvironments for tissue stimulation.  Colloids Surf B Biointerfaces  2019    PubMed ID: 31382332   DOI: 10.1016/j.colsurfb.2019.06.023
11615  He T, Shen H, Zhu J, Zhu Y, He Y, Li Z, Lu H.  Geniposide attenuates cadmium‑induced oxidative stress injury via Nrf2 signaling in osteoblasts.  Mol Med Rep  2019    PubMed ID: 31257486   DOI: 10.3892/mmr.2019.10396
11640  Tsutsumi K, Sasase T.  Cellular calcification induced by inorganic polyphosphate involves ATP depletion and opening of the mitochondrial permeability transition pore (mPTP).  FEBS Open Bio  2019    PubMed ID: 31325410   DOI: 10.1002/2211-5463.12703
11660  Damla Çetin Altındal, Menemşe Gümüşderelioğlu  Dual-functional melatonin releasing device loaded with PLGA microparticles and cyclodextrin inclusion complex for osteosarcoma therapy  Journal of Drug Delivery Science and Technology  2019      DOI: 10.1016/j.jddst.2019.05.027
11662  Vincent Irawan,Yusuke Sasaki, Toshiyuki Ikoma  Fabrication of continuous apatite-graded collagen sponges via electrolysis method  Journal of Materials Chemistry B  2019      DOI: 10.1039/C9TB00791A
11665  MA Huq, MH Siddiqi, YJ Kim, S Akter, DC Yang  Stimulating effect of fermented ginseng leaf saponin on the differentiation and mineralization of murine osteoblastic MC3T3-E1 cells  Bangladesh J. Sci. Ind.  2019      DOI: 10.3329/bjsir.v54i2.41671
11672  Junfeng Wang, Shukei Sugita, Tatsuo Michiue, Takashi Tsuboi, Tetsuya Kitaguchi, Takeo Matsumoto  A novel FRET analysis method for tension dynamics in a single actin stress fiber: Application to MC3T3-E1 cells during movement on a substrate  Journal of Biorheology  2019      DOI: 10.17106/jbr.33.21
11689  Murat Şimşek, Sevcan Dalkıranoğlu Aldemir, Menemşe Gümüşderelioğlu  Anticellular PEO coatings on titanium surfaces by sequential electrospinning and crosslinking processes  Emergent Materials  2019      DOI: 10.1007/s42247-019-00040-w
11697  Menglin Zhu, Jing Gu, Lili He, Faraz Khan Mahar, Icksoo Kim, Kai Wei  Fabrication and Osteoblastic Adhesion Behavior of Regenerated Silk Fibroin/PLLA Nanofibrous Scaffold by Double Syringe Electrospinning  Fibers and Polymers  2019      DOI: 10.1007/s12221-019-1188-7
11707  Masaya Shimabukuro, Yusuke Tsutsumi, Kosuke Nozaki, Peng Chen, Risa Yamada, Maki Ashida, Hisashi Doi, Akiko Nagai, Takao Hanawa  Chemical and Biological Roles of Zinc in a Porous Titanium Dioxide Layer Formed by Micro-Arc Oxidation  Coatings  2019      DOI: 10.3390/coatings9110705
11713  Tsuyoshi Narimiya, Hiroyuki Kanzaki, Yuki Yamaguchi, Satoshi Wada, Yuta Katsumata, Ken Tanaka, Hiroshi Tomonari  Nrf2 activation in osteoblasts suppresses osteoclastogenesis via inhibiting IL-6 expression  Bone Reports  2019    PubMed ID: 31763378   DOI: 10.1016/j.bonr.2019.100228
11731  Eiraku N, Chiba N, Nakamura T, Amir MS, Seong CH, Ohnishi T, Kusuyama J, Noguchi K, Matsuguchi T.  BMP9 directly induces rapid GSK3-β phosphorylation in a Wnt-independent manner through class I PI3K-Akt axis in osteoblasts.  FASEB J.  2019    PubMed ID: 31365832   DOI: 10.1096/fj.201900733RR
11750  Karakeçili A, Topuz B, Korpayev S, Erdek M.  Metal-organic frameworks for on-demand pH controlled delivery of vancomycin from chitosan scaffolds.  Mater Sci Eng C Mater Biol Appl  2019    PubMed ID: 31546383   DOI: 10.1016/j.msec.2019.110098
11764  Nakao N, Maki K, Mofrad MRK, Adachi T.  Talin is required to increase stiffness of focal molecular complex in its early formation process.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 31451222   DOI: 10.1016/j.bbrc.2019.08.091
11765  Abe T, Sato T, Yoda T, Hoshi K.  The period circadian clock 2 gene responds to glucocorticoids and regulates osteogenic capacity.  Regen Ther  2019    PubMed ID: 31489343   DOI: 10.1016/j.reth.2019.07.006
11813  Böhm AM, Dirckx N, Tower RJ, Peredo N, Vanuytven S, Theunis K, Nefyodova E, Cardoen R, Lindner V, Voet T, Van Hul M, Maes C.  Activation of Skeletal Stem and Progenitor Cells for Bone Regeneration Is Driven by PDGFRβ Signaling.  Dev. Cell  2019    PubMed ID: 31543445   DOI: 10.1016/j.devcel.2019.08.013
6898  Sato K, Matsubara O, Hase E, Minamikawa T, Yasui T.  Quantitative in situ time-series evaluation of osteoblastic collagen synthesis under cyclic strain using second-harmonic-generation microscopy.  J Biomed Opt  2019  24(3):1-8  PubMed ID: 30635995   DOI: 10.1117/1.JBO.24.3.031019
6930  Kojima, C., Watanabe, K., Murata, H. et al  Controlled release of DNA from zinc and magnesium ion-doped hydroxyapatites.  Res Chem Intermed   2019  45:23–32    DOI: 10.1007/s11164-018-3626-3
6935  SOO LENG LEE*, ZAINAL ARIFF ABDUL RAHMAN, HIDETSUGU TSUJIGIWA, MEI HAMADA, KIYOFUMI TAKABATAKE, KEISUKE NAKANO, HITOSHI NAGATSUKA & CHONG HUAT SIAR  An in vitro Three-Dimensional Co-Culture System for Ameloblastoma Modelling  Sains Malaysiana  2019  48(8):1697–1706    DOI: 10.17576/jsm-2019-4808-15
6944  Yo S, Hamamura K, Mishima Y, Hamajima K, Mori H, Furukawa K, Kondo H, Tanaka K, Sato T, Miyazawa K, Goto S, Togari A.  Deficiency of GD3 Synthase in Mice Resulting in the Attenuation of Bone Loss with Aging.  Int J Mol Sci  2019  20(11):2825  PubMed ID: 31185614   DOI: 10.3390/ijms20112825
8028  Machino R, Matsumoto K, Taniguchi D, Tsuchiya T, Takeoka Y, Taura Y, Moriyama M, Tetsuo T, Oyama S, Takagi K, Miyazaki T, Hatachi G, Doi R, Shimoyama K, Matsuo N, Yamasaki N, Nakayama K, Nagayasu T  Replacement of Rat Tracheas by Layered, Trachea-Like, Scaffold-Free Structures of Human Cells Using a Bio-3D Printing System.  Adv Healthc Mater  2019  8(7):e1800983  PubMed ID: 30632706   DOI: 10.1002/adhm.201800983
9889  Ki Chan, James Kit-Hon Tsoi, On-Ki Wu, Madeline Jun-Yu Yon, Ricky Wing-Kit Wong  Mechanical and Biological Evaluations of Novel Electrospun PLLA Composite Scaffolds Doped With Oxide Ceramics  J Mech Behav Biomed Mater . 2019 Sep;97:229-237.  2019  97:229-237.  PubMed ID: 31132659   DOI: 10.1016/j.jmbbm.2019.05.024
9891  Shoichi Moroi, Takayuki Miura, Takashi Tamura, Xi Zhang, Kazuhiro Ura, Yasuaki Takagi   Self-assembled Collagen Fibrils From the Swim Bladder of Bester Sturgeon Enable Alignment of MC3T3-E1 Cells and Enhance Osteogenic Differentiation  Mater Sci Eng C Mater Biol Appl  2019  104:109925  PubMed ID: 31500066   DOI: 10.1016/j.msec.2019.109925
9894  Hiraku Suzuki, Kazuaki Tatei, Noriyasu Ohshima, Seiichi Sato, Takashi Izumi  Extracellular matrix mineralization in the mouse osteoblast-like cell line MC3T3-E1 is regulated by actin cytoskeleton reorganization and non-protein molecules secreted from the cells themselves  bioRxiv  2019      DOI: 10.1101/551531
9895  Tae Yoon Park, Yun Jung Yang, Dong-Heon Ha, Dong-Woo Cho, Hyung Joon Cha  Marine-derived Natural Polymer-Based Bioprinting Ink for Biocompatible, Durable, and Controllable 3D Constructs  Biofabrication  2019  11(3):035001  PubMed ID: 30831562   DOI: 10.1088/1758-5090/ab0c6f
10369  Masaya Shimabukuro, Haruka Ito, Yusuke Tsutsumi, Kosuke Nozaki, Peng Chen, Risa Yamada, Maki Ashida, Akiko Nagai and Takao Hanawa  The Effects of Various Metallic Surfaces on Cellular and Bacterial Adhesion  Metals  2019  9(11):1145    DOI: 10.3390/met9111145
10451  Satoshi Migita, Kosuke Sakashita, Suyalatu  Osteoblast compatibility of 3D printed Co–Cr–Mo alloys with different building direction  Biosurface and Biotribology  2019  5:67    DOI: 10.1049/bsbt.2018.0043
10452  Masakazu INUBUSHI, Takuya NOTOMI, Tadashige NOZAKI  Retinoic acid promotes migration of MC3T3‐E1 osteoblast‐like cells via RARα signaling‐mediated upregulation of profilin‐1 expression  Journal of Osaka Dental University  2019  53:149-156    DOI: 10.18905/jodu.53.2_149
10458  M. Iwasaka  Deformation of cellular components of bone forming cells when exposed to a magnetic field  AIP Advances  2019  9    DOI: 10.1063/1.5079635
10467  Takuya NOTOMI, Masakazu INUBUSHI, Tadashige NOZAKI  Synaptotagmin VII affects RANKL‐lysosomal vesicle fusion to the cell membrane in osteoblast‐like cells  Journal of Osaka Dental University  2019  53:141-147    DOI: 10.18905/jodu.53.2_141
10653  Teresa Marques-AlmeidaTeresa Marques-Almeida CF-UM-UP, Centro de Física das Universidades do Minho e Porto, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal More by Teresa Marques-Almeida , Vanessa F. Cardoso*, Sylvie Ribeiro, Francisco M. Gama, Clarisse Ribeiro*, and Senentxu Lanceros-Mendez  Tuning Myoblast and Preosteoblast Cell Adhesion Site, Orientation, and Elongation through Electroactive Micropatterned Scaffolds  ACS Appl. Bio Mater  2019  2:1591–1602  PubMed ID: 35026893   DOI: 10.1021/acsabm.9b00020
10654  Takahito MIKI, Tomonori MATSUNO,Yoshiya HASHIMOTO, Akiko MIYAKE and Takafumi SATOMI  In Vitro and In Vivo Evaluation of Titanium Surface Modification for Biological Aging by Electrolytic Reducing Ionic Water  Appl Sci  2019  9(4);713    DOI: 10.3390/app9040713
11892  Fernandes MM, Correia DM, Ribeiro C, Castro N, Correia V, Lanceros-Mendez S.  Bioinspired Three-Dimensional Magnetoactive Scaffolds for Bone Tissue Engineering.  ACS Appl Mater Interfaces  2019    PubMed ID: 31682095   DOI: 10.1021/acsami.9b14001
11895  Park E, Kim J, Yeo S, Lim E, Choi CW, Choi S, Li WY, Lee JW, Park JH, Huh D, Jeong SY.  Anti-Osteoporotic Effects of Combined Extract of Lycii Radicis Cortex and Achyranthes japonica in Osteoblast and Osteoclast Cells and Ovariectomized Mice.  Nutrients  2019    PubMed ID: 31717518   DOI: 10.3390/nu11112716
11950  Gümüşderelioğlu M, Sunal E, Tolga Demirtaş T, Kiremitçi AS.  Chitosan-based double-faced barrier membrane coated with functional nanostructures and loaded with BMP-6.  J Mater Sci Mater Med  2019    PubMed ID: 31832785   DOI: 10.1007/s10856-019-6331-x
11066  Masaya ShimabukuroMasaya, Yusuke Tsutsumi, Risa Yamada, Maki Ashida, Peng Chen, Hisashi Doi, Kosuke Nozaki, Akiko Nagai, and Takao Hanawa  Investigation of Realizing Both Antibacterial Property and Osteogenic Cell Compatibility on Titanium Surface by Simple Electrochemical Treatment  ACS Biomater Sci Eng  2019  5623–5630  PubMed ID: 33405692   DOI: 10.1021/acsbiomaterials.8b01058
11069  Gülseren Irmak, Tuǧrul Tolga Demirtaş, and Menemşe Gümüşderelioǧlu  Highly Methacrylated Gelatin Bioink for Bone Tissue Engineering  ACS Biomater Sci Eng  2019  831–845  PubMed ID: 33405843   DOI: 10.1021/acsbiomaterials.8b00778
11469  E. Çatıker ORCID Icon,E. Konuk,T. Gültan &M. Gümüşderelioğlu  Enhancement of scaffolding properties for poly(3-hydroxybutyrate): blending with poly-β-alanine and wet electrospinning  International Journal of Polymeric Materials and Polymeric Biomaterials  2019  338-349    DOI: 10.1080/00914037.2018.1552862
12507  Kazi GAS, Rahman KA, Farahat M, Matsumoto T.  Fabrication of single gel with different mechanical stiffness using three-dimensional mold  J Biomed Mater Res A  2019  107(1):6-11  PubMed ID: 29781218   DOI: 10.1002/jbm.a.36455
12508  Liu H, Yang M, Wu G, Yang L, Cao Y, Liu C, Tan Z, Jin Y, Guo J, Zhu L.  Effects of different oxygen concentrations on the proliferation, survival, migration, and osteogenic differentiation of MC3T3-E1 cells  Connect Tissue Res  2019  60(3):240-253  PubMed ID: 29916278   DOI: 10.1080/03008207.2018.1487413
12509  Ishida H, Haniu H, Takeuchi A, Ueda K, Sano M, Tanaka M, Takizawa T, Sobajima A, Kamanaka T, Saito N.  In Vitro and In Vivo Evaluation of Starfish Bone-Derived β-Tricalcium Phosphate as a Bone Substitute Material  Materials (Basel)  2019  12(11):1881  PubMed ID: 31212709   DOI: 10.3390/ma12111881
12510  Morakul S, Otsuka Y, Ohnuma K, Tagaya M, Motozuka S, Miyashita Y, Mutoh Y.  Enhancement effect on antibacterial property of gray titania coating by plasma-sprayed hydroxyapatite-amino acid complexes during irradiation with visible light  Heliyon  2019  5(8):e02207  PubMed ID: 31517079   DOI: 10.1016/j.heliyon.2019.e02207
12511  Miyamoto H, Sawaji Y, Iwaki T, Masaoka T, Fukada E, Date M, Yamamoto K.  Intermittent pulsed electromagnetic field stimulation activates the mTOR pathway and stimulates the proliferation of osteoblast-like cells  Bioelectromagnetics  2019  40(6):412-421  PubMed ID: 31338867   DOI: 10.1002/bem.22207
12512  Cao NQ, Le HM, Pham KM, Nguyen NV, Hiromoto S, Kobayashi E.  In Vitro Corrosion and Cell Response of Hydroxyapatite Coated Mg Matrix in Situ Composites for Biodegradable Material Applications  Materials (Basel)  2019  12(21):3474  PubMed ID: 31652717   DOI: 10.3390/ma12213474
12513  Takahashi A, Morita T, Murata K, Minowa E, Jahan A, Saito M, Tanimura A.  Effects of full-length human amelogenin on the differentiation of dental epithelial cells and osteoblastic cells  Arch Oral Biol  2019  107:104479  PubMed ID: 31330473   DOI: 10.1016/j.archoralbio.2019.07.004
12514  Isoshima K, Ueno T, Arai Y, Saito H, Chen P, Tsutsumi Y, Hanawa T, Wakabayashi N.  The change of surface charge by lithium ion coating enhances protein adsorption on titanium  J Mech Behav Biomed Mater  2019  100:103393  PubMed ID: 31450101   DOI: 10.1016/j.jmbbm.2019.103393
12515  Baba TT, Miyazaki T, Ohara-Nemoto Y, Nemoto TK.  Suppressive effects of N-bisphosphonate in osteoblastic cells mitigated by non-N-bisphosphonate but not by sodium-dependent phosphate cotransporter inhibitor  Cell Biochem Funct  2019  37(6):400-407  PubMed ID: 31328801   DOI: 10.1002/cbf.3418
12592  Takeno A, Kanazawa I, Tanaka KI, Notsu M, Sugimoto T.  Phloretin Suppresses Bone Morphogenetic Protein-2-Induced Osteoblastogenesis and Mineralization via Inhibition of Phosphatidylinositol 3-kinases/Akt Pathway  Int J Mol Sci  2019  20(10):2481  PubMed ID: 31137461   DOI: 10.3390/ijms20102481
12978  Kojima C, Narita Y, Nakajima Y, Morimoto N, Yoshikawa T, Takahashi N, Handa A, Waku T, Tanaka N.  Modulation of Cell Adhesion and Differentiation on Collagen Gels by the Addition of the Ovalbumin Secretory Signal Peptide.  ACS Biomater Sci Eng  2019    PubMed ID: 33405701   DOI: 10.1021/acsbiomaterials.8b01505
14878  Toshihiko Shiraishi, Kota Nagai  A Study of Mechanosensing of an Osteoblast at Focal Adhesions Under Cyclic Strain Using Magnetic Micropillars  Biomedical and Biotechnology Engineering  2019  3    DOI: 10.1115/imece2019-11132
14886  Yoneda M, Suzuki H, Hatano N, Nakano S, Muraki Y, Miyazawa K, Goto S, Muraki K.  PIEZO1 and TRPV4, which Are Distinct Mechano-Sensors in the Osteoblastic MC3T3-E1 Cells, Modify Cell-Proliferation  Int J Mol Sci  2019  20(19):4960  PubMed ID: 31597314   DOI: 10.3390/ijms20194960
10429  Nakatsu Y, Nakagawa F, Higashi S, Ohsumi T, Shiiba S, Watanabe S, Takeuchi H.  Effect of acetaminophen on osteoblastic differentiation and migration of MC3T3-E1 cells.  Pharmacol Rep  2018  70:29-36  PubMed ID: 29306760   DOI: 10.1016/j.pharep.2017.07.006
10469  Matsuyama A, Higashi S, Tanizaki S, Morotomi T, Washio A, Ohsumi T, Kitamura C, Takeuchi H.  Celecoxib inhibits osteoblast differentiation independent of cyclooxygenase activity.  Clin. Exp. Pharmacol. Physiol.  2018  45:75-83  PubMed ID: 28815657   DOI: 10.1111/1440-1681.12846
10542  Matsumoto K, Shimo T, Kurio N, Okui T, Ibaragi S, Kunisada Y, Obata K, Masui M, Pai P, Horikiri Y, Yamanaka N, Takigawa M, Sasaki A.  Low-intensity pulsed ultrasound stimulation promotes osteoblast differentiation through hedgehog signaling.  J. Cell. Biochem.  2018  119:4352-4360  PubMed ID: 28981158   DOI: 10.1002/jcb.26418
10643  Mikami R, Mizutani K, Aoki A, Tamura Y, Aoki K, Izumi Y.  Low-level ultrahigh-frequency and ultrashort-pulse blue laser irradiation enhances osteoblast extracellular calcification by upregulating proliferation and differentiation via transient receptor potential vanilloid 1.  Lasers Surg Med  2018  50:340-352  PubMed ID: 29214666   DOI: 10.1002/lsm.22775
10657  Kawai S, Yamauchi M, Amano A.  Zinc-finger transcription factor Odd-skipped related 1 regulates cranial bone formation.  J. Bone Miner. Metab.  2018  36(6):640-647  PubMed ID: 29234951   DOI: 10.1007/s00774-017-0885-9
10666  Takeno A, Kanazawa I, Notsu M, Tanaka KI, Sugimoto T.  Inhibition of adenosine monophosphate-activated protein kinase suppresses bone morphogenetic protein-2-induced mineralization of osteoblasts via Smad-independent mechanisms.  Endocr. J.  2018  65:291-298  PubMed ID: 29249772   DOI: 10.1507/endocrj.EJ17-0229
10701  Kunimatsu R, Gunji H, Tsuka Y, Yoshimi Y, Awada T, Sumi K, Nakajima K, Kimura A, Hiraki T, Abe T, Naoto H, Yanoshita M, Tanimoto K.  Effects of high-frequency near-infrared diode laser irradiation on the proliferation and migration of mouse calvarial osteoblasts.  Lasers Med Sci  2018  33(5):959-966  PubMed ID: 29302842   DOI: 10.1007/s10103-017-2426-0
10716  Kwon BJ, Seon GM, Lee MH, Koo MA, Kim MS, Kim D, Han JJ, Kim D, Kim J, Park JC.  Locally delivered ethyl-2,5-dihydroxybenzoate using 3D printed bone implant for promotion of bone regeneration in a osteoporotic animal model.  Eur Cell Mater  2018  35:1-12  PubMed ID: 29327779   DOI: 10.22203/eCM.v035a01
10764  Takeda T, Tsubaki M, Tomonari Y, Kawashima K, Itoh T, Imano M, Satou T, Nishida S.  Bavachin induces the apoptosis of multiple myeloma cell lines by inhibiting the activation of nuclear factor kappa B and signal transducer and activator of transcription 3.  Biomed. Pharmacother.  2018  100:486-494  PubMed ID: 29477912   DOI: 10.1016/j.biopha.2018.02.019
10789  Yang DU, Siddiqi MH, Ahn S, Kang S, Noh HY, Yang DC.  In vitro evaluation of the potential therapeutic role of Dendropanax morbifera extract in ameliorating osteoporosis and resultant bone impairment using MC3T3-E1 cells.  In Vitro Cell. Dev. Biol. Anim.  2018  54:346-354  PubMed ID: 29560558   DOI: 10.1007/s11626-018-0242-x
10802  Funaki Y, Hasegawa Y, Okazaki R, Yamasaki A, Sueda Y, Yamamoto A, Yanai M, Fukushima T, Harada T, Makino H, Shimizu E.  Resolvin E1 Inhibits Osteoclastogenesis and Bone Resorption by Suppressing IL-17-induced RANKL Expression in Osteoblasts and RANKL-induced Osteoclast Differentiation.  Yonago Acta Med  2018  61:8-18  PubMed ID: 29599617   DOI: 10.33160/yam.2018.03.002
10846  Fushimi S, Nohno T, Nagatsuka H, Katsuyama H.  Involvement of miR-140-3p in Wnt3a and TGFβ3 signaling pathways during osteoblast differentiation in MC3T3-E1 cells.  Genes Cells  2018  23(7):517-527  PubMed ID: 29740905   DOI: 10.1111/gtc.12591
11034    A systematic study for optimal cell seeding and culture conditions in a perfusion mode bone-tissue bioreactor  Biochemical Engineering Journal  2018  132, 100-111    DOI: 10.1016/j.bej.2018.01.006
11041    Ciona intestinalis calcitonin-like peptide promotes osteoblast differentiation and mineralization through MAPK pathway in MC3T3-E1 cells  Process Biochemistry  2018  67, 127-138    DOI: 10.1016/j.procbio.2018.01.025
11068    The Synergistic Effects of IL-6/IL-17A Promote Osteogenic Differentiation by Improving OPG/RANKL Ratio and Adhesion of MC3T3-E1 Cells on Hydroxyapatite  Journal of Cranio-Maxillofacial Surgery  2018  46,1361-1367  PubMed ID: 29805067   DOI: 10.1016/j.jcms.2018.05.002
11077  Kato K, Morita K, Hirata I, Doi K, Kubo T, Kato K, Tsuga K.  Enhancement of calcification by osteoblasts cultured on hydroxyapatite surfaces with adsorbed inorganic polyphosphate.  In Vitro Cell. Dev. Biol. Anim.  2018  54(6):449-457  PubMed ID: 29766357   DOI: 10.1007/s11626-018-0257-3
11129  Gonzalez-Garcia C, Cantini M, Ballester-Beltran J, Altankov G, Salmeron-Sanchez M.  The strength of the protein-material interaction determines cell fate.  Acta Biomater  2018  77:74-84  PubMed ID: 30006313   DOI: 10.1016/j.actbio.2018.07.016
11146  Fujioka-Kobayashi M, Tsuru K, Nagai H, Fujisawa K, Kudoh T, Ohe G, Ishikawa K, Miyamoto Y.  Fabrication and evaluation of carbonate apatite-coated calcium carbonate bone substitutes for bone tissue engineering.  J Tissue Eng Regen Med  2018  12(10):2077-2087  PubMed ID: 30058260   DOI: 10.1002/term.2742
11221  Khalid H, Suhaib F, Zahid S, Ahmed S, Jamal A, Kaleem M, Khan AS.  Microwave-assisted synthesis and in vitro osteogenic analysis of novel bioactive glass fibers for biomedical and dental applications.  Biomed Mater  2018    PubMed ID: 30251708   DOI: 10.1088/1748-605X/aae3f0
11138  Fukuda M, Yoshizawa T, Karim MF, Sobuz SU, Korogi W, Kobayasi D, Okanishi H, Tasaki M, Ono K, Sawa T, Sato Y, Chirifu M, Masuda T, Nakamura T, Tanoue H, Nakashima K, Kobashigawa Y, Morioka H, Bober E, Ohtsuki S, Yamagata Y, Ando Y, Oike Y, Araki N, Takeda S, Mizuta H, Yamagata K.  SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix.  Nat Commun  2018  9(1):2833  PubMed ID: 30026585   DOI: 10.1038/s41467-018-05187-4
11254  Bai Y, Kanno T, Tatsumi H, Miyamoto K, Sha J, Hideshima K, Matsuzaki Y.  Feasibility of a Three-Dimensional Porous Uncalcined and Unsintered Hydroxyapatite/poly-d/l-lactide Composite as a Regenerative Biomaterial in Maxillofacial Surgery.  Materials (Basel)  2018    PubMed ID: 30347816   DOI: 10.3390/ma11102047
11265  Sato M, Asano T, Hosomichi J, Ono T, Nakata T.  Optogenetic manipulation of intracellular calcium by BACCS promotes differentiation of MC3T3-E1 cells.  Biochem. Biophys. Res. Commun.  2018    PubMed ID: 30376992   DOI: 10.1016/j.bbrc.2018.10.107
11261  Marcotti S, Maki K, Reilly GC, Lacroix D, Adachi T.  Hyaluronic acid selective anchoring to the cytoskeleton: An atomic force microscopy study.  PLoS ONE  2018    PubMed ID: 30359403   DOI: 10.1371/journal.pone.0206056
11267  Oyane A, Nakamura M, Sakamaki I, Shimizu Y, Miyata S, Miyaji H.  Laser-assisted wet coating of calcium phosphate for surface-functionalization of PEEK.  PLoS ONE  2018    PubMed ID: 30379904   DOI: 10.1371/journal.pone.0206524
11352  Choi H, Magyar CE, Nervina JM, Tetradis S.  Different duration of parathyroid hormone exposure distinctively regulates primary response genes Nurr1 and RANKL in osteoblasts.  PLoS ONE  2018    PubMed ID: 30576321   DOI: 10.1371/journal.pone.0208514
4411  Yuka Yashima, View ORCID ProfileMasato Kaku, Taeko Yamamoto, Jin Izumino, Haruka Kagawa, Kotaro Tanimoto  Effect of continuous compressive force on the expression of RANKL, OPG, and VEGF in MC3T3-E1 and MLO-Y4 cells  bioRxiv  2018  19    DOI: 10.1101/474254
4412  Katsuya SATO, Manabu KATAYAMA, Shoichiro FUJISAWA, Tasuku NAKAHARA, Kazuyuki MINAMI  Evaluation of initiating characteristics of osteoblastic calcium signaling responses to stretch by video rate time-course observation  Journal of Biomechanical Science and Engineering  2018  13    DOI: 10.1299/jbse.17-00519
4413  Abbas Teimouri, Email author, Shahin Roohafza, Mohammad Azadi, Alireza Najafi Chermahini  Fabrication and characterization of chitosan/gelatin/nanodiopside composite scaffolds for tissue engineering application  Polymer Bulletin  2018  75:1487–1504    DOI: 10.1007/s00289-017-2096-x
4414    Visible light-induced antibacterial effects of the luminescent complex of hydroxyapatite and 8-hydroxyquinoline with gray titania coating  Applied Surface Science  2018  448, 529-538    DOI: 10.1016/j.apsusc.2018.04.106
4416    Collagen-derived X-Hyp-Gly-type tripeptides promote differentiation of MC3T3-E1 pre-osteoblasts  Journal of Functional Foods  2018  46, 456-462    DOI: 10.1016/j.jff.2018.05.017
4417    Improving Magnetoelectric Contactless Sensing and Actuation through Anisotropic Nanostructures  J. Phys. Chem.  2018  122:19189-9196    DOI: 10.1021/acs.jpcc.8b04910
4418  Nobuo Izumo et al  Effects of lactoferrin on dexamethasone-induced osteoporosis in mice  Take a look at the Recent articles  2018  3(3):5-5    DOI: 10.15761/GDT.1000149
4419  Kubota T, Hasuike A, Tsukune N, Ozawa Y, Yamamoto T, Min S, Naito M5, Sato S.  Influence of estrogen deficiency on guided bone augmentation: investigation of rat calvarial model and osteoblast‐like MC3T3‐E1 cells  Eur J Oral Sci  2018  126(3):206-213  PubMed ID: 29676477   DOI: 10.1111/eos.12415
4281  Takahashi A, Mulati M, Saito M, Numata H, Kobayashi Y, Ochi H, Sato S, Kaldis P, Okawa A, Inose H.  Loss of cyclin-dependent kinase 1 impairs bone formation, but does not affect the bone-anabolic effects of parathyroid hormone.  J. Biol. Chem.  2018    PubMed ID: 30366983   DOI: 10.1074/jbc.RA118.004834
4282  Ando K, Imagama S, Kobayashi K, Ito K, Tsushima M, Morozumi M, Tanaka S, Machino M, Ota K, Nishida K, Nishida Y, Ishiguro N.  Effects of a self-assembling peptide as a scaffold on bone formation in a defect.  PLoS ONE  2018    PubMed ID: 29304115   DOI: 10.1371/journal.pone.0190833
4283  Kawamoto K, Miyaji H, Nishida E, Miyata S, Kato A, Tateyama A, Furihata T, Shitomi K, Iwanaga T, Sugaya T.  Characterization and evaluation of graphene oxide scaffold for periodontal wound healing of class II furcation defects in dog.  Int J Nanomedicine  2018    PubMed ID: 29713167   DOI: 10.2147/IJN.S163206
4489  iho Inoue, Mio Naritani, Resmi Raju, Mayu Miyagi, Masamitsu Oshima, Masahisa Inoue and Yoshizo Matsuka  Effect of Short-term Tumour Necrosis Factor-alpha (TNF-α)-stimulation on the Growth and Differentiation of MC3T3-E1 Osteoblast-like Cells  Journal of Hard Tissue Biology  2018  27:213-218    DOI: 10.2485/jhtb.27.213
4490  Kenichi Matsuzaka, Tadashi Horikawa, Eitoyo Kokubu and Takashi Inoue  Oral epithelial cells inhibit the proliferation, mRNA expressions of collagen type I, RUNX2 and BGP, and ALP activity of osteoblast-like cells in co-culture.  Biomedical Research  2018  29 (15):3085-3089    DOI: 10.4066/biomedicalresearch.29-18-900
4491  Graef JL, Rendina-Ruedy E, Crockett EK, Ouyang P, King JB, Cichewicz RH, Lucas EA, Smith BJ.  Select polyphenolic fractions from dried plum enhance osteoblast activity through BMP-2 signaling.  J. Nutr. Biochem.  2018  55:59-67  PubMed ID: 29413490   DOI: 10.1016/j.jnutbio.2017.09.014
4493  Yoshihara C, Ueno T, Chen P, Tsutsumi Y, Hanawa T, Wakabayashi N.  Inverse response of osteoblasts and fibroblasts to growth on carbon-deposited titanium surfaces.  J. Biomed. Mater. Res. Part B Appl. Biomater.  2018  106(5):1869-1877  PubMed ID: 28926194   DOI: 10.1002/jbm.b.33996
9463  Takashi Takizawa, Noboru Nakayama, Hisao Haniu, Kaoru Aoki, Masanori Okamoto, Hiroki Nomura, Manabu Tanaka, Atsushi Sobajima, Kazushige Yoshida, Takayuki Kamanaka, Kumiko Ajima, Ayumu Oishi, Chika Kuroda, Haruka Ishida, Satomi Okano, Shinsuke Kobayashi, Hiroyuki Kato, and Naoto Saito  Titanium Fiber Plates for Bone Tissue Repair  Adv Mater  2018  30:1703608  PubMed ID: 29215204   DOI: 10.1002/adma.201703608
9464  Mariko Urata, Shoichiro Kokabu, Takuma Matsubara, Goro Sugiyama, Chihiro Nakatomi, Hiroshi Takeuchi, Shizu Hirata-Tsuchiya, Kazuhiro Aoki, Yukihiko Tamura, Yasuko Moriyama, Yasunori Ayukawa, Miho Matsuda, Min Zhang, Kiyoshi Koyano, Chiaki Kitamura, Eijiro Jimi  A Peptide That Blocks the Interaction of NF-κB p65 Subunit With Smad4 Enhances BMP2-induced Osteogenesis  J Cell Physiol  2018  233(9):7356-7366  PubMed ID: 29663368   DOI: 10.1002/jcp.26571
9465  Tomohiko Tokunaga, Takashi Ando, Miki Suzuki-Karasaki, Tomohisa Ito, Asuka Onoe-Takahashi, Toyoko Ochiai, Masayoshi Soma , Yoshihiro Suzuki-Karasaki  Plasma-stimulated Medium Kills TRAIL-resistant Human Malignant Cells by Promoting Caspase-Independent Cell Death via Membrane Potential and Calcium Dynamics Modulation  Int J Oncol  2018  52(3):697-708  PubMed ID: 29393427   DOI: 10.3892/ijo.2018.4251
14601  Ilyas K, Qureshi SW, Afzal S, Gul R, Yar M, Kaleem M, Khan AS.  Microwave-assisted synthesis and evaluation of type 1 collagen-apatite composites for dental tissue regeneration  J Biomater Appl  2018  33(1):103-115  PubMed ID: 29720018   DOI: 10.1177/0885328218773220
14908  Jeong Y, Jo YK, Kim BJ, Yang B, Joo KI, Cha HJ.  Sprayable Adhesive Nanotherapeutics: Mussel-Protein-Based Nanoparticles for Highly Efficient Locoregional Cancer Therapy  ACS Nano  2018  12(9):8909-8919  PubMed ID: 30052423   DOI: 10.1021/acsnano.8b04533
9716  Kitagawa M, Ando T, Subarnbhesaj A, Uchida T, Miyauchi M, Takata T.  N-terminal region of human ameloblastin synthetic peptide promotes bone formation.  Odontology  2017  105:116-121  PubMed ID: 27262724   DOI: 10.1007/s10266-016-0243-8
9825  Teimouri A, Azadi M, Shams Ghahfarokhi Z, Razavizadeh R.  Preparation and characterization of novel β-chitin/nanodiopside/nanohydroxyapatite composite scaffolds for tissue engineering applications.  J Biomater Sci Polym Ed  2017  28:1-14  PubMed ID: 27604099   DOI: 10.1080/09205063.2016.1231437
9870  Takano-Yamamoto T, Fukunaga T, Takeshita N.  Gene Expression Analysis of CCN Protein in Bone Under Mechanical Stress.  Methods Mol. Biol.  2017  1489:283-308  PubMed ID: 27734385   DOI: 10.1007/978-1-4939-6430-7_26
9876  Kaynak Bayrak G, Demirtaş TT, Gümüşderelioğlu M.  Microwave-induced biomimetic approach for hydroxyapatite coatings of chitosan scaffolds.  Carbohydr Polym  2017  157:803-813  PubMed ID: 27987994   DOI: 10.1016/j.carbpol.2016.10.016
9934  Kanazawa I, Tomita T, Miyazaki S, Ozawa E, Yamamoto LA, Sugimoto T.  Bazedoxifene Ameliorates Homocysteine-Induced Apoptosis and Accumulation of Advanced Glycation End Products by Reducing Oxidative Stress in MC3T3-E1 Cells.  Calcif. Tissue Int.  2017  100:286-297  PubMed ID: 27832315   DOI: 10.1007/s00223-016-0211-x
9942  Pawaputanon Na Mahasarakham C, Izu Y, Nishimori K, Izumi Y, Noda M, Ezura Y.  Lgr4 Expression in Osteoblastic Cells Is Suppressed by Hydrogen Peroxide Treatment.  J. Cell. Physiol.  2017  232:1761-1766  PubMed ID: 27861872   DOI: 10.1002/jcp.25684
9951  Ode T, Podyma-Inoue KA, Terasawa K, Inokuchi JI, Kobayashi T, Watabe T, Izumi Y, Hara-Yokoyama M.  PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum.  Exp. Cell Res.  2017  350:103-114  PubMed ID: 27865938   DOI: 10.1016/j.yexcr.2016.11.011
9960  Noguchi T, Ebina K, Hirao M, Morimoto T, Koizumi K, Kitaguchi K, Matsuoka H, Iwahashi T, Yoshikawa H.  Oxygen ultra-fine bubbles water administration prevents bone loss of glucocorticoid-induced osteoporosis in mice by suppressing osteoclast differentiation.  Osteoporos Int  2017  28:1063-1075  PubMed ID: 27896363   DOI: 10.1007/s00198-016-3830-1
9976  Katsumura S, Izu Y, Yamada T, Griendling K, Harada K, Noda M, Ezura Y.  FGF Suppresses Poldip2 Expression in Osteoblasts.  J. Cell. Biochem.  2017  118:1670-1677  PubMed ID: 27918072   DOI: 10.1002/jcb.25813
9994  Arahira T, Maruta M, Matsuya S.  Characterization and in vitro evaluation of biphasic α-tricalcium phosphate/β-tricalcium phosphate cement.  Mater Sci Eng C Mater Biol Appl  2017  74:478-484  PubMed ID: 28254321   DOI: 10.1016/j.msec.2016.12.049
10042  Tunçay EÖ, Demirtaş TT, Gümüşderelioğlu M.  Microwave-induced production of boron-doped HAp (B-HAp) and B-HAp coated composite scaffolds.  J Trace Elem Med Biol  2017  40:72-81  PubMed ID: 28159225   DOI: 10.1016/j.jtemb.2016.12.005
10058  Nagao M, Tanabe N, Manaka S, Naito M, Sekino J, Takayama T, Kawato T, Torigoe G, Kato S, Tsukune N, Maeno M, Suzuki N, Sato S.  LIPUS suppressed LPS-induced IL-1α through the inhibition of NF-κB nuclear translocation via AT1-PLCβ pathway in MC3T3-E1 cells.  J. Cell. Physiol.  2017  232:3337-3346  PubMed ID: 28063227   DOI: 10.1002/jcp.25777
10068  Sato Y, Ishihara N, Nagayama D, Saiki A, Tatsuno I.  7-ketocholesterol induces apoptosis of MC3T3-E1 cells associated with reactive oxygen species generation, endoplasmic reticulum stress and caspase-3/7 dependent pathway.  Mol Genet Metab Rep  2017  10:56-60  PubMed ID: 28116245   DOI: 10.1016/j.ymgmr.2017.01.006
10074  Takano A, Fukuda T, Shinjo T, Iwashita M, Matsuzaki E, Yamamichi K, Takeshita M, Sanui T, Nishimura F.  Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation.  Metab. Clin. Exp.  2017  69:157-170  PubMed ID: 28285646   DOI: 10.1016/j.metabol.2017.01.006
10084  Kodama D, Hirai T, Kondo H, Hamamura K, Togari A.  Bidirectional communication between sensory neurons and osteoblasts in an in vitro coculture system.  FEBS Lett.  2017  591:527-539  PubMed ID: 28094440   DOI: 10.1002/1873-3468.12561
10139  Tsukune N, Naito M, Kubota T, Ozawa Y, Nagao M, Ohashi A, Sato S, Takahashi T.  Lamin A overexpression promotes osteoblast differentiation and calcification in the MC3T3-E1 preosteoblastic cell line.  Biochem. Biophys. Res. Commun.  2017  488:664-670  PubMed ID: 28237702   DOI: 10.1016/j.bbrc.2017.02.110
10140  Tanaka M, Sato Y, Haniu H, Nomura H, Kobayashi S, Takanashi S, Okamoto M, Takizawa T, Aoki K, Usui Y, Oishi A, Kato H, Saito N.  A three-dimensional block structure consisting exclusively of carbon nanotubes serving as bone regeneration scaffold and as bone defect filler.  PLoS ONE  2017  12:e0172601  PubMed ID: 28235026   DOI: 10.1371/journal.pone.0172601
10217  Kusuyama J, Bandow K, Ohnishi T, Hisadome M, Shima K, Semba I, Matsuguchi T.  Osteopontin inhibits osteoblast responsiveness through the down-regulation of focal adhesion kinase mediated by the induction of low-molecular weight protein tyrosine phosphatase.  Mol. Biol. Cell  2017  28:1326-1336  PubMed ID: 28331074   DOI: 10.1091/mbc.E16-10-0716
10349  Sekiguchi Y, Mano H, Nakatani S, Shimizu J, Kataoka A, Ogura K, Kimira Y, Ebata M, Wada M.  Mangiferin positively regulates osteoblast differentiation and suppresses osteoclast differentiation.  Mol Med Rep  2017  16:1328-1332  PubMed ID: 28627701   DOI: 10.3892/mmr.2017.6752
10352  Nathanael AJ, Oyane A, Nakamura M, Sakamaki I, Nishida E, Kanemoto Y, Miyaji H.  In Vitro and in Vivo Analysis of Mineralized Collagen-Based Sponges Prepared by a Plasma- and Precursor-Assisted Biomimetic Process.  ACS Appl Mater Interfaces  2017  9:22185-22194  PubMed ID: 28621514   DOI: 10.1021/acsami.7b04776
10376  Nagao M, Tanabe N, Manaka S, Takayama T, Kawato T, Torigoe G, Sekino J, Tsukune N, Ozaki M, Maeno M, Suzuki N, Sato S.  Low-intensity pulsed ultrasound inhibits lipopolysaccharide-induced IL-6 and RANKL expression in osteoblasts.  J Oral Sci  2017  59:303-309  PubMed ID: 28637991   DOI: 10.2334/josnusd.16-0624
10405  Yahara M, Tei K, Tamura M.  Inhibition of neuropeptide Y Y1 receptor induces osteoblast differentiation in MC3T3‑E1 cells.  Mol Med Rep  2017  16:2779-2784  PubMed ID: 28656295   DOI: 10.3892/mmr.2017.6866
10441  Rodriguez R, Yoshimura K, Shibata Y, Miyamoto Y, Tanaka R, Uyama R, Sasa K, Suzuki D, Miyazaki T, Kamijo R.  Nanoindentation time-dependent deformation/recovery suggestive of methylglyoxal induced glycation in calcified nodules.  Nanomedicine  2017  13:2545-2553  PubMed ID: 28754466   DOI: 10.1016/j.nano.2017.07.003
10502  Chen P, Miyake M, Tsukamoto M, Tsutsumi Y, Hanawa T.  Response of preosteoblasts to titanium with periodic micro/nanometer scale grooves produced by femtosecond laser irradiation.  J Biomed Mater Res A  2017  105:3456-3464  PubMed ID: 28879673   DOI: 10.1002/jbm.a.36202
10528  Saiki A, Motoyoshi M, Motozawa K, Okamura T, Ueki K, Shimizu N, Asano M.  EMMPRIN Inhibits bFGF-Induced IL-6 Secretion in an Osteoblastic Cell Line, MC3T3-E1.  Int J Med Sci  2017  14:1173-1180  PubMed ID: 29104472   DOI: 10.7150/ijms.20387
10565  Torigoe G, Nagao M, Tanabe N, Manaka S, Kariya T, Kawato T, Sekino J, Kato S, Maeno M, Suzuki N, Shimizu N.  PYK2 mediates BzATP-induced extracellular matrix proteins synthesis.  Biochem. Biophys. Res. Commun.  2017  494:663-667  PubMed ID: 29061307   DOI: 10.1016/j.bbrc.2017.10.107
10903    Surface chemistry and osteoblast-like cell response on a titanium surface modified by a focused Nd:YAG laser  Surface and Coatings Technology  2017  309, 220-226    DOI: 10.1016/j.surfcoat.2016.10.024
10909    Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications  Composites Part B: Engineering  2017  111, 37-44    DOI: 10.1016/j.compositesb.2016.12.014
10918    Effects of a Chemically Synthesized Leucine-Rich Amelogenin Peptide (csLRAP) on Chondrogenic and Osteogenic Cells  Journal of Hard Tissue Biology  2017  26, 51- 60    DOI: 10.2485/jhtb.26.51
10920  A. Ghanem, Yunhe Lu, Tianyi Cai, Xiongzheng Mu   Overexpression of RBP4 promotes proliferation, differentiation and mineralization of MC3T3-E1  Int J Clin Exp Pathol  2017  10:298-305   
10928    Enhance the Bioactivity and Osseointegration of the Polyethylene-Terephthalate-Based Artificial Ligament via Poly(Dopamine) Coating with Mesoporous Bioactive Glass  Advanced Engineering Materials banner  2017  19    DOI: 10.1002/adem.201600708
10935    Antibacterial effect of nickel-titanium alloy owing to nickel ion release  Applied Surface Science  2017  405, 215-219    DOI: 10.1016/j.apsusc.2017.02.037
10970    Evaluation of the enhancement of osteogenesis by Zn-releasing diamond-like carbon film  Diamond and Related Materials  2017  77, 131-136    DOI: 10.1016/j.diamond.2017.06.006
10982    Development of a Ta/TaN/TaNx(Ag)y/TaN nanocomposite coating system and bio-response study for biomedical applications  Vacuum  2017  145, 55-67    DOI: 10.1016/j.vacuum.2017.08.020
10989    Effects of three-dimensional culture of mouse calvaria-derived osteoblastic cells in a collagen gel with a multichannel structure on the morphogenesis behaviors of engineered bone tissues  ACS Biomater. Sci. Eng.  2017  3 , 3414–3424  PubMed ID: 33445380   DOI: 10.1021/acsbiomaterials.7b00190
10998    Antibacterial and cytotoxic effects of photoexcited Au clusters via blue high-power or white low-power lightemitting diode irradiation  Biology, Engineering and Medicine  2017  2:4    DOI: 10.15761/BEM.1000126
11001    Anti-Osteoporotic Effects of Kukoamine B in Osteoblast and Osteoclast Cells and Ovariectomized Mice  medicinal chemistry  2017  2017100196    DOI: 10.20944/preprints201710.0196.v1
11013    In Situ Observation and Measurement of Actin Stress Fiber Deformation in Stretched Osteoblast like Cell  Advances in Bioscience and Biotechnology,  2017  8, 421-433    DOI: 10.4236/abb.2017.811031
11044    Attachment of Mouse Osteoblast-like Cells onto Fibronectin-or Albumin-immobilized Poly (Lactic Acid-ε-Caprolactone) Films  Journal of Oral Tissue Engineering  2017  15, 3-10    DOI: 10.11223/jarde.15.3
4521  Drago Skrtic and Joseph M. Antonucci  Bioactive ACP-Based Polymeric Biocomposite  Biomaterials for Tissue Engineering  2017  4:90-142    DOI: 10.2174/97816810853641170401
6639  Ota T, Nishida Y, Ikuta K, Kato R, Kozawa E, Hamada S, Sakai T, Ishiguro N.  Heat-stimuli-enhanced osteogenesis using clinically available biomaterials.  PLoS One  2017  12(7):e0181404  PubMed ID: 28719650   DOI: 10.1371/journal.pone.0181404
9435  Takuya Yasukawa, Makoto Hayashi, Natsuko Tanabe, Hiromasa Tsuda, Yusuke Suzuki, Takayuki Kawato, Naoto Suzuki, Masao Maeno, Bunnai Ogiso  Involvement of the Calcium-Sensing Receptor in Mineral Trioxide Aggregate-Induced Osteogenic Gene Expression in Murine MC3T3-E1 Cells  Dent Mater J  2017  36(4):469-475  PubMed ID: 28228629   DOI: 10.4012/dmj.2016-313
9436  Midori Katsuyama, Masashi Demura, Hironobu Katsuyama, Hideji Tanii, Kiyofumi Saijoh  Genistein and menaquinone-4 Treatment-Induced Alterations in the Expression of mRNAs and Their Products Are Beneficial to Osteoblastic MC3T3-E1 Cell Functions  Mol Med Rep  2017  6(1):873-880  PubMed ID: 28560445   DOI: 10.3892/mmr.2017.6632
9438  Haruaki Kitagawa, Kahoru Takeda, Ririko Tsuboi, Mikako Hayashi, Jun-Ichi Sasaki, Satoshi Imazato  Influence of Polymerization Properties of 4-META/MMA-based Resin on the Activity of Fibroblast Growth factor-2  Dent Mater J  2017  36(6):724-730  PubMed ID: 28626207   DOI: 10.4012/dmj.2016-372
9439  Saori Miyata, Hirofumi Miyaji, Hideya Kawasaki, Masaki Yamamoto, Erika Nishida, Hiroko Takita, Tsukasa Akasaka, Natsumi Ushijima, Toshihiko Iwanaga, Tsutomu Sugaya  Antimicrobial Photodynamic Activity and Cytocompatibility of Au 25(Capt) 18 Clusters Photoexcited by Blue LED Light Irradiation  Int J Nanomedicine . 2017 Apr 4;12:2703-2716  2017  12:2703-2716  PubMed ID: 28435253   DOI: 10.2147/IJN.S131602
9440  Keisuke Yasuda, Yohei Okazaki, Yasuhiko Abe, Kazuhiro Tsuga  Effective UV/Ozone Irradiation Method for Decontamination of Hydroxyapatite Surfaces  Heliyon  2017  3(8):e00372  PubMed ID: 28795167   DOI: 10.1016/j.heliyon.2017.e00372
9441  Satoshi Migita and Kunitaka Araki   Effect of nanometer scale surface roughness of titanium for osteoblast function  AIMS Bioengineering   2017  4:162-170   
9442  Mohammad Azadi, Zahra Shams Ghahfarokhi and Abbas Teimouri  Modification of Silk Fibroin and Gelatin-Chondroitin Sulfate Matrix with the Addition of Nanohydroxyapatite by FreezeDrying Method for Tissue Engineering Application  J Pharm Appl Chem   2017  3:253-258    DOI: 10.18576/jpac/030308
9443  Manami Ozaki, Tadahiro Takayama, Takanobu Yamamoto, Yasumasa Ozawa, Mayu Nagao, Natsuko Tanabe, Akira Nakajima, Naoto Suzuki, Masao Maeno, Seiichi Yamano, Shuichi Sato  A Collagen Membrane Containing Osteogenic protein-1 Facilitates Bone Regeneration in a Rat Mandibular Bone Defect  Arch Oral Biol   2017  84:19-28  PubMed ID: 28938197   DOI: 10.1016/j.archoralbio.2017.09.005
9444  Yoko Oshima, Fuminori Iwasa, Keita Tachi, Kazuyoshi Baba  Effect of Nanofeatured Topography on Ceria-Stabilized Zirconia/Alumina Nanocomposite on Osteogenesis and Osseointegration  Int J Oral Maxillofac Implants  2017  32(1):81-91  PubMed ID: 28095516   DOI: 10.11607/jomi.4366
9445  Manabu Tanaka, Hisao Haniu, Takayuki Kamanaka, Takashi Takizawa, Atsushi Sobajima, Kazushige Yoshida, Kaoru Aoki, Masanori Okamoto, Hiroyuki Kato, Naoto Saito  Physico-Chemical, In Vitro, and In Vivo Evaluation of a 3D Unidirectional Porous Hydroxyapatite Scaffold for Bone Regeneration  Materials (Basel) . 2017 Jan 3;10(1):33  2017  10(1):33  PubMed ID: 28772390   DOI: 10.3390/ma10010033
9446  Shusuke Murakami, Hirofumi Miyaji, Erika Nishida, Kohei Kawamoto, Saori Miyata, Hiroko Takita, Tsukasa Akasaka, Bunshi Fugetsu, Toshihiko Iwanaga, Hiromi Hongo, Norio Amizuka, Tsutomu Sugaya, Masamitsu Kawanami  Dose Effects of Beta-Tricalcium Phosphate Nanoparticles on Biocompatibility and Bone Conductive Ability of Three-Dimensional Collagen Scaffolds  Dent Mater J  2017  36(5):573-583  PubMed ID: 28450672   DOI: 10.4012/dmj.2016-295
9449  Tuğrul Tolga Demirtaş, Gülseren Irmak, Menemşe Gümüşderelioğlu  A Bioprintable Form of Chitosan Hydrogel for Bone Tissue Engineering  Biofabrication  2017  9(3):035003  PubMed ID: 28639943   DOI: 10.1088/1758-5090/aa7b1d
9453  Jussi Ryynänen, Carsten Kriebitzsch, Mark B Meyer, Iris Janssens, J Wesley Pike, Lieve Verlinden, Annemieke Verstuyf   Class 3 Semaphorins Are Transcriptionally Regulated by 1,25(OH) 2 D 3 in Osteoblasts  Steroid Biochem Mol Biol   2017  173:185-193  PubMed ID: 28189595   DOI: 10.1016/j.jsbmb.2017.02.005
9455  Sachiko Nitta, Ayaka Komatsu, Taisei Ishii, Masatoshi Ohnishi, Atsuko Inoue, Hiroyuki Iwamoto  Fabrication and Characterization of Water-Dispersed Chitosan Nanofiber/Poly(ethylene Glycol) Diacrylate/Calcium Phosphate-Based Porous Composites  Carbohydr Polym  2017  174:1034-1040  PubMed ID: 28821025   DOI: 10.1016/j.carbpol.2017.06.111
9456  H Iijima, A Ito, M Nagai, J Tajino, S Yamaguchi, W Kiyan, A Nakahata, J Zhang, T Wang, T Aoyama, K Nishitani, H Kuroki  Physiological Exercise Loading Suppresses Post-Traumatic Osteoarthritis Progression via an Increase in Bone Morphogenetic Proteins Expression in an Experimental Rat Knee Model  Osteoarthritis Cartilage  2017  25(6):964-975  PubMed ID: 27965139   DOI: 10.1016/j.joca.2016.12.008
9458  Kosaku Kurata, Junpei Matsushita, Atsushi Furuno, Junichi Fujino, Hiroshi Takamatsu  Assessment of Thermal Damage in Total Knee Arthroplasty Using an Osteocyte Injury Model  J Orthop Res  2017  35(12):2799-2807  PubMed ID: 28485534   DOI: 10.1002/jor.23600
14575  Chunrong Yang, Huazhong Wu, Jianhua Wang  Fabrication of Multiple Layered Scaffolds with Controlled Porous Micro-Architecture  Materials Research  2017  20:349-355    DOI: 10.1590/1980-5373-mr-2016-0703
14662  Yuki Nakamura, Toshihiko Shiraishi  A Study of a Cell Mechanosensing System Under Mechanical Vibration Considering its Modes of Vibration and Calcium Ion Response  Volume 3: Biomedical and Biotechnology Engineering  2017      DOI: 10.1115/imece2017-71363
14751  Tanaka M, Sato Y, Zhang M, Haniu H, Okamoto M, Aoki K, Takizawa T, Yoshida K, Sobajima A, Kamanaka T, Kato H, Saito N.  In Vitro and In Vivo Evaluation of a Three-Dimensional Porous Multi-Walled Carbon Nanotube Scaffold for Bone Regeneration  Nanomaterials (Basel)  2017  7(2):46  PubMed ID: 28336879   DOI: 10.3390/nano7020046
14771  Yang C, Wu H, Wang J.  Effect of steroidal saponins-loaded nano-bioglass/phosphatidylserine/collagen bone substitute on bone healing  Biomed Tech (Berl)  2017  62(5):487-491  PubMed ID: 27831915   DOI: 10.1515/bmt-2016-0151
7091  M Azadi, A Teimouri, G Mehranzadeh  Preparation, characterization and biocompatible properties of β-chitin/silk fibroin/nanohydroxyapatite composite scaffolds prepared by freeze-drying method.  RSC Adv  2016  6:7048-7060    DOI: 10.1039/C5RA22987A
7108  Demirta? TT, Goz E, Karakecili A, Gumu?derelio?lu M.  Combined delivery of PDGF-BB and BMP-6 for enhanced osteoblastic differentiation.  J Mater Sci Mater Med  2016  27:12  PubMed ID: 26676858   DOI: 10.1007/s10856-015-5626-9
7118  Shirakawa J, Harada H, Noda M, Ezura Y.  PTH-Induced Osteoblast Proliferation Requires Upregulation of the Ubiquitin-Specific Peptidase 2 (Usp2) Expression.  Calcif. Tissue Int.  2016  98:306-15  PubMed ID: 26643174   DOI: 10.1007/s00223-015-0083-5
7136  Valanezhad A, Odatsu T, Udoh K, Shiraishi T, Sawase T, Watanabe I.  Modification of resin modified glass ionomer cement by addition of bioactive glass nanoparticles.  J Mater Sci Mater Med  2016  27:3  PubMed ID: 26610926   DOI: 10.1007/s10856-015-5614-0
7164  Yoneshima E, Okamoto K, Sakai E, Nishishita K, Yoshida N, Tsukuba T.  The Transcription Factor EB (TFEB) Regulates Osteoblast Differentiation Through ATF4/CHOP-Dependent Pathway.  J. Cell. Physiol.  2016  231:1321-33  PubMed ID: 26519689   DOI: 10.1002/jcp.25235
7178  Chen P, Nagai A, Tsutsumi Y, Ashida M, Doi H, Hanawa T.  Differences in the calcification of preosteoblast cultured on sputter-deposited titanium, zirconium, and gold.  J Biomed Mater Res A  2016  104:639-651  PubMed ID: 26488234   DOI: 10.1002/jbm.a.35598
7211  Nakamoto T, Izu Y, Kawasaki M, Notomi T, Hayata T, Noda M, Ezura Y.  Mice Deficient in CIZ/NMP4 Develop an Attenuated Form of K/BxN-Serum Induced Arthritis.  J. Cell. Biochem.  2016  117:970-7  PubMed ID: 26378628   DOI: 10.1002/jcb.25382
7282  Taniguchi Y, Kakura K, Yamamoto K, Kido H, Yamazaki J.  Accelerated Osteogenic Differentiation and Bone Formation on Zirconia with Surface Grooves Created with Fiber Laser Irradiation.  Clin Implant Dent Relat Res  2016  18:883-894  PubMed ID: 26179832   DOI: 10.1111/cid.12366
9510  Ribeiro C, Correia V, Martins P, Gama FM, Lanceros-Mendez S.  Proving the suitability of magnetoelectric stimuli for tissue engineering applications.  Colloids Surf B Biointerfaces  2016  140:430-436  PubMed ID: 26797659   DOI: 10.1016/j.colsurfb.2015.12.055
9521  Tanaka K, Hirai T, Kodama D, Kondo H, Hamamura K, Togari A.  α1B -Adrenoceptor signalling regulates bone formation through the up-regulation of CCAAT/enhancer-binding protein δ expression in osteoblasts.  Br. J. Pharmacol.  2016  173:1058-69  PubMed ID: 26750808   DOI: 10.1111/bph.13418
9528  Ogawa K, Miyaji H, Kato A, Kosen Y, Momose T, Yoshida T, Nishida E, Miyata S, Murakami S, Takita H, Fugetsu B, Sugaya T, Kawanami M.  Periodontal tissue engineering by nano beta-tricalcium phosphate scaffold and fibroblast growth factor-2 in one-wall infrabony defects of dogs.  J. Periodont. Res.  2016  51:758-767  PubMed ID: 27870141   DOI: 10.1111/jre.12352
9565  Iwatsuki M, Matsuoka M.  Fluoride-induced c-Fos expression in MC3T3-E1 osteoblastic cells.  Toxicol. Mech. Methods  2016  26:132-8  PubMed ID: 26862884   DOI: 10.3109/15376516.2015.1129570
9570  Yoo HY, Song YH, Foo M, Seo E, Hwang DS, Seo JH.  Recombinant mussel proximal thread matrix protein promotes osteoblast cell adhesion and proliferation.  BMC Biotechnol.  2016  16:16  PubMed ID: 26879700   DOI: 10.1186/s12896-016-0247-z
9596  Pengjam Y, Madhyastha H, Madhyastha R, Yamaguchi Y, Nakajima Y, Maruyama M.  Anthraquinone Glycoside Aloin Induces Osteogenic Initiation of MC3T3-E1 Cells: Involvement of MAPK Mediated Wnt and Bmp Signaling.  Biomol Ther (Seoul)  2016  24:123-31  PubMed ID: 26869456   DOI: 10.4062/biomolther.2015.106
9597  Kumagai M, Mishima T, Watanabe A, Harada T, Yoshida I, Fujita K, Watai M, Tawata S, Nishikawa K, Morimoto Y.  5,6-Dehydrokawain from Alpinia zerumbet promotes osteoblastic MC3T3-E1 cell differentiation.  Biosci. Biotechnol. Biochem.  2016  80:1425-32  PubMed ID: 26940726   DOI: 10.1080/09168451.2016.1153959
9626  Saito A, Yoshimura K, Miyamoto Y, Kaneko K, Chikazu D, Yamamoto M, Kamijo R.  Enhanced and suppressed mineralization by acetoacetate and β-hydroxybutyrate in osteoblast cultures.  Biochem. Biophys. Res. Commun.  2016  473:537-44  PubMed ID: 27018251   DOI: 10.1016/j.bbrc.2016.03.109
9655  Hase E, Matsubara O, Minamikawa T, Sato K, Yasui T.  In situ time-series monitoring of collagen fibers produced by standing-cultured osteoblasts using a second-harmonic-generation microscope.  Appl Opt  2016  55:3261-7  PubMed ID: 27140096   DOI: 10.1364/AO.55.003261
9683  Tamura K, Naraba H, Hara T, Nakamura K, Yoshie M, Kogo H, Tachikawa E.  A positive feedback loop between progesterone and microsomal prostaglandin E synthase-1-mediated PGE2 promotes production of both in mouse granulosa cells.  Prostaglandins Other Lipid Mediat.  2016  123:56-62  PubMed ID: 27174800   DOI: 10.1016/j.prostaglandins.2016.05.002
9689  Correia DM, Sencadas V, Ribeiro C, Martins PM, Martins P, Gama FM, Botelho G, Lanceros-Méndez S.  Processing and size range separation of pristine and magnetic poly(l-lactic acid) based microspheres for biomedical applications.  J Colloid Interface Sci  2016  476:79-86  PubMed ID: 27209393   DOI: 10.1016/j.jcis.2016.05.012
9707  Zhang Q, Matsui H, Horiuchi H, Liang X, Sasaki K.  A-Raf and C-Raf differentially regulate mechanobiological response of osteoblasts to guide mechanical stress-induced differentiation.  Biochem. Biophys. Res. Commun.  2016  476:438-444  PubMed ID: 27240957   DOI: 10.1016/j.bbrc.2016.05.141
9745  Kang S, Siddiqi MH, Yoon SJ, Ahn S, Noh HY, Kumar NS, Kim YJ, Yang DC.  Therapeutic potential of compound K as an IKK inhibitor with implications for osteoarthritis prevention: an in silico and in vitro study.  In Vitro Cell. Dev. Biol. Anim.  2016  52:895-905  PubMed ID: 27368432   DOI: 10.1007/s11626-016-0062-9
9772  Sato M, Chen P, Tsutsumi Y, Shiota M, Hanawa T, Kasugai S.  Effect of strontium ions on calcification of preosteoblasts cultured on porous calcium- and phosphate-containing titanium oxide layers formed by micro-arc oxidation.  Dent Mater J  2016  35:627-34  PubMed ID: 27477229   DOI: 10.4012/dmj.2016-032
9776  Rendina-Ruedy E, Graef JL, Lightfoot SA, Ritchey JW, Clarke SL, Lucas EA, Smith BJ.  Impaired glucose tolerance attenuates bone accrual by promoting the maturation of osteoblasts: Role of Beclin1-mediated autophagy.  Bone Rep  2016  5:199-207  PubMed ID: 28580387   DOI: 10.1016/j.bonr.2016.08.001
9782  Chawalitpong S, Sornkaew N, Suksamrarn A, Palaga T.  Diarylheptanoid from Curcuma comosa Roxb. suppresses RANKL-induced osteoclast differentiation by decreasing NFATc1 and c-Fos expression via MAPK pathway.  Eur. J. Pharmacol.  2016  788:351-359  PubMed ID: 27523282   DOI: 10.1016/j.ejphar.2016.08.012
9832  Yang D, Okamura H, Morimoto H, Teramachi J, Haneji T.  Protein phosphatase 2A Cα regulates proliferation, migration, and metastasis of osteosarcoma cells.  Lab. Invest.  2016  96:1050-62  PubMed ID: 27617401   DOI: 10.1038/labinvest.2016.82
9850  Park E, Kim MC, Choi CW, Kim J, Jin HS, Lee R, Lee JW, Park JH, Huh D, Jeong SY.  Effects of Dihydrophaseic Acid 3'-O-β-d-Glucopyranoside Isolated from Lycii radicis Cortex on Osteoblast Differentiation.  Molecules  2016  21(9). pii: E1260  PubMed ID: 27657033   DOI: 10.3390/molecules21091260
10849  Junfeng WANG, Shukei SUGITA, Kazuaki NAGAYAMA, Takeo MATSUMOTO  Dynamics of actin filaments of MC3T3-E1 cells during adhesion process to substrate  Journal of Biomechanical Science and Engineering  2016  11:15-00637    DOI: 10.1299/jbse.15-00637
10858  Oki Matsubara; Eiji Hase; Takeo Minamikawa; Takeshi Yasui; Katsuya Sato  In situ quantitative evaluation of osteoblastic collagen synthesis under cyclic strain by using second-harmonic-generation microscope  SPIE BiOS  2016  9721    DOI: 10.1117/12.2214008
10860    Fabrication and in vitro characterization of electrospun poly (γ-glutamic acid)-silica hybrid scaffolds for bone regeneration  Polymer  2016  91,106-117    DOI: 10.1016/j.polymer.2016.03.056
10865    Functional peptide KP24 enhances submandibular gland tissue growth in vitro  Regenerative Therapy  2016  3, 108-113  PubMed ID: 31245481   DOI: 10.1016/j.reth.2016.02.006
10872    β-Chitin/gelatin/nanohydroxyapatite composite scaffold prepared through freeze-drying method for tissue engineering applications  Polymer Bulletin  2016  73, 3513–3529    DOI: 10.1007/s00289-016-1691-6
10876    Advanced DLC coating technique on silicone-based tubular medical devices  Surface and Coatings Technology  2016  307, 1084-1087    DOI: 10.1016/j.surfcoat.2016.06.067
10897    Modification of Composite Resin Surface with Carbon Nanotubes Enhances Cell Proliferation  Nano Biomedicine  2016  8    DOI: 10.11344/nano.8.27
10898    Observations of intracellular tension dynamics of MC3T3-E1 cells during substrate adhesion using a FRET-based actinin tension sensor  Journal of Biomechanical Science and Engineering  2016  11:16-00504    DOI: 10.1299/jbse.16-00504
10900    Cytocompatibility of Ti–6Al–7Nb through High-Pressure Torsion Processing  MATERIALS TRANSACTIONS  2016  57, 2020-2025    DOI: 10.2320/matertrans.MI201515
10901    Cell Activity on Type 316L Stainless Steel with Self-Organized Nanopores Formed by Anodic Polarization  Journal of the Japan Institute of Metals and Materials  2016  57:2065-2071    DOI: 10.2320/matertrans.MI201516
7763  Wang L, Hsu HY, Li X, Xian CJ.  Effects of Frequency and Acceleration Amplitude on Osteoblast Mechanical Vibration Responses: A Finite Element Study.  Biomed Res Int  2016  2016:2735091  PubMed ID: 28074178   DOI: 10.1155/2016/2735091
9377  Nur Farahiyah Mohammad,Radzali Othman , Nurul Asma Abdullah, Fei Yee YEOH  In vitro Evaluation of Mesoporous Carbonated Hydroxyapatite in MC3T3-E1 Osteoblast Cells  Procedia Chemistry  2016  19 :259 – 266     DOI: 10.1016/j.proche.2016.03.103
9402  S M Marques, P Rico I Carvalho, J L Gómez Ribelles, L Fialho, S Lanceros-Méndez, M Henriques, S Carvalho  MC3T3-E1 Cell Response to Ti1-xAgx and Ag-TiNx Electrodes Deposited on Piezoelectric Poly(vinylidene Fluoride) Substrates for Sensor Applications  ACS Appl Mater Interfaces  2016  8(6):4199-207  PubMed ID: 26840928   DOI: 10.1021/acsami.5b11922
9409  Nobutaka Sato 1, Jiro Ichikawa 1, Masanori Wako, Tetsuro Ohba, Masanori Saito, Hironao Sato, Kensuke Koyama, Tetsuo Hagino, Jonathan G Schoenecker, Takashi Ando, Hirotaka Haro  Thrombin Induced by the Extrinsic Pathway and PAR-1 Regulated Inflammation at the Site of Fracture Repair  Bone  2016  83:23-34  PubMed ID: 26475502   DOI: 10.1016/j.bone.2015.10.005
9410  Sunarso, Riki Toita, Kanji Tsuru, Kunio Ishikawa  Immobilization of Calcium and Phosphate Ions Improves the Osteoconductivity of Titanium Implants  Mater Sci Eng C Mater Biol Appl   2016  68:291-298  PubMed ID: 27524023   DOI: 10.1016/j.msec.2016.05.090
9411  Chen Chen, Hong Li, Changan Guo, Shiyi Chen  Preparation and in vitro Evaluation of a Biomimetic Nanoscale Calcium Phosphate Coating on a Polyethylene Terephthalate Artificial Ligament  Exp Ther Med  2016  12(1):302-306  PubMed ID: 27347053   DOI: 10.3892/etm.2016.3269
9412  Masahiko Terauchi, Takasuke Inada, Asato Tonegawa, Atsushi Tamura, Satoshi Yamaguchi, Kiyoshi Harada, Nobuhiko Yui  Supramolecular Inclusion Complexation of Simvastatin With Methylated β-Cyclodextrins for Promoting Osteogenic Differentiation  Int J Biol Macromol  2016  93(Pt B):1492-1498  PubMed ID: 26845478   DOI: 10.1016/j.ijbiomac.2016.01.114
9413  Erika Nishida, Hirofumi Miyaji, Akihito Kato, Hiroko Takita, Toshihiko Iwanaga, Takehito Momos, Kosuke Ogawa, Shusuke Murakami, Tsutomu Sugaya, Masamitsu Kawanami  Graphene Oxide Scaffold Accelerates Cellular Proliferative Response and Alveolar Bone Healing of Tooth Extraction Socket  Int J Nanomedicine   2016  11:2265-77  PubMed ID: 27307729   DOI: 10.2147/IJN.S104778
9415  Wanting Lin, Yoichi Ezura, Yayoi Izu, Smriti A C Aryal, Makiri Kawasaki, Pawaputanon Na Mahasarakham Chantida, Keiji Moriyama, Masaki Noda  Profilin Expression Is Regulated by Bone Morphogenetic Protein (BMP) in Osteoblastic Cells  J Cell Biochem  2016  117(3):621-8  PubMed ID: 26271366   DOI: 10.1002/jcb.25310
9417  Aysu Arslan, Soner Çakmak, Alper Cengiz, Menemşe Gümüşderelioğlu  Poly(butylene Adipate-Co-Terephthalate) Scaffolds: Processing, Structural Characteristics and Cellular Responses  J Biomater Sci Polym Ed  2016  27(18):1841-1859  PubMed ID: 27724793   DOI: 10.1080/09205063.2016.1239945
9420  Abbas Teimouri &Mohammad Azadi  Preparation and characterization of novel chitosan/nanodiopside/nanohydroxyapatite composite scaffolds for tissue engineering applications  International Journal of Polymeric Materials and Polymeric Biomaterials  2016  65:18    DOI: 10.1080/00914037.2016.1180606
9421  Yoshikazu Mikami, Hiromasa Tsuda, Yuko Akiyama, Masaki Honda, Noriyoshi Shimizu, Naoto Suzuki, Kazuo Komiyama  Alkaline Phosphatase Determines Polyphosphate-Induced Mineralization in a Cell-Type Independent Manner  J Bone Miner Metab  2016  34(6):627-637  PubMed ID: 26475372   DOI: 10.1007/s00774-015-0719-6
9422  Kumi Futawaka, Tetsuya Tagami, Yuki Fukuda, Rie Koyama, Ayaka Nushida, Shoko Nezu, Hironori Yamamoto, Miyuki Imamoto, Masato Kasahara, Kenji Moriyama  Transcriptional Activation of the Wild-Type and Mutant Vitamin D Receptors by Vitamin D3 Analogs  J Mol Endocrinol  2016  57(1):23-32  PubMed ID: 27154546   DOI: 10.1530/JME-16-0048
9423  Taegon Kang, Xavier Banquy, Jinhwa Heo, Chanoong Lim, Nathaniel A Lynd, Pontus Lundberg, Dongyeop X Oh, Han-Koo Lee, Yong-Ki Hong 2, Dong Soo Hwang, John Herbert Waite, Jacob N Israelachvili, Craig J Hawker  Mussel-Inspired Anchoring of Polymer Loops That Provide Superior Surface Lubrication and Antifouling Properties  ACS Nano  2016  10(1):930-7  PubMed ID: 26695175   DOI: 10.1021/acsnano.5b06066
9424  Ling Jin, Yosuke Nonaka, Shin Miyakawa, Masatoshi Fujiwara, Yoshikazu Nakamura  Dual Therapeutic Action of a Neutralizing Anti-FGF2 Aptamer in Bone Disease and Bone Cancer Pain  Mol Ther  2016  24(11):1974-1986  PubMed ID: 27506449   DOI: 10.1038/mt.2016.158
9425  Alexander C Allori, Edward H Davidson, Derek D Reformat, Alexander M Sailon, James Freeman, Adam Vaughan, David Wootton, Elizabeth Clark, John L Ricci, Stephen M Warren  Design and Validation of a Dynamic Cell-Culture System for Bone Biology Research and Exogenous Tissue-Engineering Applications  J Tissue Eng Regen Med  2016  10(10):E327-E336  PubMed ID: 24027138   DOI: 10.1002/term.1810
9426  Yuri Nakashima , Toru Mima, Mitsuru Yashiro, Tomohiro Sonou, Masaki Ohya, Asuka Masumoto, Shintaro Yamanaka, Daisuke Koreeda, Koichi Tatsuta, Yoshiyuki Hanba, Mari Moribata, Shigeo Negi, Takashi Shigematsu  Expression and Localization of Fibroblast Growth Factor (FGF)23 and Klotho in the Spleen: Its Physiological and Functional Implications  Growth Factors  2016  34(5-6):196-202  PubMed ID: 28095739   DOI: 10.1080/08977194.2016.1273222
9429  Drago Skrtic, Joseph M Antonucci  Polymeric Dental Composites Based on Remineralizing Amorphous Calcium Phosphate Fillers  Curr Trends Polym Sci   2016  17:1-31  PubMed ID: 29599572  
9451  Masanobu Kamitakahara, Takashi Shirato, Taishi Yokoi, Hideaki Matsubara, Yasuaki Shibata, Tohru Ikeda  Effect of Silicate Incorporation in Alpha-Tricalcium Phosphate on Behaviors of Osteoblast-Like Cells  Key Engineering Materials  2016  720:90-94    DOI: 10.4028/
12931  Ozeki N, Mogi M, Hase N, Hiyama T, Yamaguchi H, Kawai R, Kondo A, Nakata K.  Wnt16 Signaling Is Required for IL-1β-Induced Matrix Metalloproteinase-13-Regulated Proliferation of Human Stem Cell-Derived Osteoblastic Cells  Int J Mol Sci  2016  17(2):221  PubMed ID: 26861315   DOI: 10.3390/ijms17020221
13950  Zhu C, Zheng XF, Yang YH, Li B, Wang YR, Jiang SD, Jiang LS.  LGR4 acts as a key receptor for R-spondin 2 to promote osteogenesis through Wnt signaling pathway  Cell Signal  2016  28(8):989-1000  PubMed ID: 27140682   DOI: 10.1016/j.cellsig.2016.04.010
14148  Toshihiko Shiraishi, Tomohiro Fukuno  Cell Response to Cyclic Strain at Focal Adhesions  Biomedical and Biotechnology Engineering  2016  3    DOI: 10.1115/imece2016-66843
16612  Nnamchi PS, Obayi CS, Todd I, Rainforth MW.  Mechanical and electrochemical characterisation of new Ti-Mo-Nb-Zr alloys for biomedical applications  J Mech Behav Biomed Mater  2016  60:68-77  PubMed ID: 26773649   DOI: 10.1016/j.jmbbm.2015.12.023
7163  Nishide Y, Tousen Y, Tadaishi M, Inada M, Miyaura C, Kruger MC, Ishimi Y.  Combined Effects of Soy Isoflavones and β-Carotene on Osteoblast Differentiation.  Int J Environ Res Public Health  2015  12:13750-61  PubMed ID: 26516892   DOI: 10.3390/ijerph121113750
7220  Yang YJ, Tsou HK, Chen YH, Chung CJ, He JL.  Enhancement of bioactivity on medical polymer surface using high power impulse magnetron sputtered titanium dioxide film.  Mater Sci Eng C Mater Biol Appl  2015  57:58-66  PubMed ID: 26354240   DOI: 10.1016/j.msec.2015.07.039
7229  Inoue K, Imai Y.  Fatostatin, an SREBP inhibitor, prevented RANKL-induced bone loss by suppression of osteoclast differentiation.  Biochim. Biophys. Acta  2015  1852:2432-41  PubMed ID: 26319416   DOI: 10.1016/j.bbadis.2015.08.018
7241  Noguchi T, Ebina K, Hirao M, Kawase R, Ohama T, Yamashita S, Morimoto T, Koizumi K, Kitaguchi K, Matsuoka H, Kaneshiro S, Yoshikawa H.  Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-α-induced osteoclastogenesis and promoting osteoblastic differentiation in mice.  Biochem. Biophys. Res. Commun.  2015  465:638-43  PubMed ID: 26297947   DOI: 10.1016/j.bbrc.2015.08.077
7290  Uchino K, Okamoto K, Sakai E, Yoneshima E, Iwatake M, Fukuma Y, Nishishita K, Tsukuba T.  Dual Effects of Liquiritigenin on the Proliferation of Bone Cells: Promotion of Osteoblast Differentiation and Inhibition of Osteoclast Differentiation.  Phytother Res  2015  29:1714-21  PubMed ID: 26172226   DOI: 10.1002/ptr.5416
7302  Wang CH, Guo ZS, Pang F, Zhang LY, Yan M, Yan JH, Li KW, Li XJ, Li Y, Bi L, Han YS.  Effects of graphene modification on the bioactivation of polyethylene-terephthalate-based artificial ligaments.  ACS Appl Mater Interfaces  2015  7:15263-76  PubMed ID: 26111253   DOI: 10.1021/acsami.5b02893
7307  Hatano M, Matsumoto Y, Fukushi J, Matsunobu T, Endo M, Okada S, Iura K, Kamura S, Fujiwara T, Iida K, Fujiwara Y, Nabeshima A, Yokoyama N, Fukushima S, Oda Y, Iwamoto Y.  Cadherin-11 regulates the metastasis of Ewing sarcoma cells to bone.  Clin. Exp. Metastasis  2015  32:579-91  PubMed ID: 26092671   DOI: 10.1007/s10585-015-9729-y
7309  Fukuda K, Sugihara E, Ohta S, Izuhara K, Funakoshi T, Amagai M, Saya H.  Periostin Is a Key Niche Component for Wound Metastasis of Melanoma.  PLoS ONE  2015  10:e0129704  PubMed ID: 26083413   DOI: 10.1371/journal.pone.0129704
7309  Fukuda K, Sugihara E, Ohta S, Izuhara K, Funakoshi T, Amagai M, Saya H.  Periostin Is a Key Niche Component for Wound Metastasis of Melanoma.  PLoS ONE  2015  10:e0129704  PubMed ID: 26083413   DOI: 10.1371/journal.pone.0129704
7325  Tanaka K, Hirai T, Ishibashi Y, Izumo N, Togari A.  Modulation of osteoblast differentiation and bone mass by 5-HT2A receptor signaling in mice.  Eur. J. Pharmacol.  2015  762:150-7  PubMed ID: 26026645   DOI: 10.1016/j.ejphar.2015.05.048
7332  Gumu?derelio?lu M, Tuncay EO, Kaynak G, Demirta? TT, Ayd?n ST, Hakk? SS.  Encapsulated boron as an osteoinductive agent for bone scaffolds.  J Trace Elem Med Biol  2015  31:120-8  PubMed ID: 26004902   DOI: 10.1016/j.jtemb.2015.03.008
7338  Kaneshiro S, Otsuki D, Yoshida K, Yoshikawa H, Higuchi C.  MEK5 suppresses osteoblastic differentiation.  Biochem. Biophys. Res. Commun.  2015  463:241-7  PubMed ID: 25998381   DOI: 10.1016/j.bbrc.2015.05.035
7374  Yang D, Okamura H, Teramachi J, Haneji T.  Histone demethylase Utx regulates differentiation and mineralization in osteoblasts.  J. Cell. Biochem.  2015  116:2628-36  PubMed ID: 25920016   DOI: 10.1002/jcb.25210
7431  Lin H, Gao X, Chen G, Sun J, Chu J, Jing K, Li P, Zeng R, Wei B.  Indole-3-carbinol as inhibitors of glucocorticoid-induced apoptosis in osteoblastic cells through blocking ROS-mediated Nrf2 pathway.  Biochem. Biophys. Res. Commun.  2015  460:422-7  PubMed ID: 25795137   DOI: 10.1016/j.bbrc.2015.03.049
7441  Terasawa K, Rajapakshe AR, Podyma-Inoue KA, Mishima-Tsumagari C, Yanagishita M, Hara-Yokoyama M.  Preferential recognition of isocitrate dehydrogenase by a rabbit monoclonal antibody (ab124797) against the C-terminal peptide of RANKL.  J. Immunol. Methods  2015  420:1-10  PubMed ID: 25771969   DOI: 10.1016/j.jim.2015.03.006
7444  Siddiqi MZ, Siddiqi MH, Kim YJ, Jin Y, Huq MA, Yang DC.  Effect of Fermented Red Ginseng Extract Enriched in Ginsenoside Rg3 on the Differentiation and Mineralization of Preosteoblastic MC3T3-E1 Cells.  J Med Food  2015  18:542-8  PubMed ID: 25764149   DOI: 10.1089/jmf.2014.3251
7445  Koike T, Mikami T, Shida M, Habuchi O, Kitagawa H.  Chondroitin sulfate-E mediates estrogen-induced osteoanabolism.  Sci Rep  2015  5:8994  PubMed ID: 25759206   DOI: 10.1038/srep08994
7455  Yamamura K, Miura T, Kou I, Muramatsu T, Furusawa M, Yoshinari M.  Influence of various superhydrophilic treatments of titanium on the initial attachment, proliferation, and differentiation of osteoblast-like cells.  Dent Mater J  2015  34:120-7  PubMed ID: 25748468   DOI: 10.4012/dmj.2014-076
7480  Saito T, Teraoka K, Ota K.  Arrayed three-dimensional structures designed to induce and maintain a cell pattern by a topographical effect on cell behavior.  Mater Sci Eng C Mater Biol Appl  2015  49:256-61  PubMed ID: 25686947   DOI: 10.1016/j.msec.2015.01.021
7491  Okito A, Nakahama K, Akiyama M, Ono T, Morita I.  Involvement of the G-protein-coupled receptor 4 in RANKL expression by osteoblasts in an acidic environment.  Biochem. Biophys. Res. Commun.  2015  458:435-40  PubMed ID: 25668130   DOI: 10.1016/j.bbrc.2015.01.142
7519  Abbas Teimouri, Mohammad Azadi, Rahmatollah Emadi, Jalil Lari, Alireza Najafi Chermahini  Preparation, characterization, degradation and biocompatibility of different silk fibroin based composite scaffolds prepared by freeze-drying method for tissue engineering application.  Polym Degrad Stab  2015  121:18-29    DOI: 10.1016/j.polymdegradstab.2015.08.004
7531  Hsien-Te Chen, Hui-Ying Shu, Chi-Jen Chung, Ju-Liang He  Assessment of Bone Morphogenic Protein and Hydroxyapatite-Titanium Dioxide Composites for Bone Implant Materials.  Surface and Coatings Technology  2015  276:168-174    DOI: 10.1016/j.surfcoat.2015.06.056
7538  Katsuya SATO, Yuki OGAWA, Shin-ichi ITO, Shoichiro FUJISAWA, Kazuyuki MINAMI  Strain magnitude dependent intracellular calcium signaling response to uniaxial stretch in osteoblastic cells.  J Biomechanical Science and Engineering  2015  10:15-00242    DOI: 10.1299/jbse.15-00242
7541  L.T. Bang, S. Ramesha,. Purbolaksono, Y.C. Chinga, B.D. Long, Hari Chandran, S. Rameshc, R. Othmand  Effects of silicate and carbonate substitution on the properties of hydroxyapatite prepared by aqueous co-precipitation method.  Materials and Design  2015  87:788?796    DOI: 10.1016/j.matdes.2015.08.069
7543  M. Hirano, M. Yamane, N. Ohtsu  Surface characteristics and cell-adhesion performance of titanium treated with direct-current gas plasma comprising nitrogen and oxygen.  Appl Surf Sci.   2015  354:161-167    DOI: 10.1016/j.apsusc.2015.02.153
7546  Megumi Fuse, Tohru Hayakawa, Tomomi Hashizume-Takizawa, Reiri Takeuchi, Tomoko Kurita-Ochiai, Junko Fujita-Yoshigaki, Masahiko Fukumoto  MC3T3-E1 Cell Assay on Collagen or Fibronectin Immobilized Poly (Lactic Acid-ε-Caprolactone) Film.  J Hard Tissue Biology  2015  24:249-256    DOI: 10.2485/jhtb.24.249
7549  Momoko Takahashi, Masaru Yamaguchi, Yasuhiro Tanimoto, Eriko Yao-Umezawa, Kazutaka Kasai  Biological Evaluation of a Prototype Material made of Polyglycolic Acid and Hydroxyapatite.  J Hard Tissue Biology  2015  24:375-384    DOI: 10.2485/jhtb.24.375
7551  Naofumi Ohtsu, Taro Kozuka, Mitsuhiro Hirano, Hirofumi Arai  Electrolyte effects on the surface chemistry and cellular response of anodized titanium.  Appl Surf Sci.   2015  349:911-915    DOI: 10.1016/j.apsusc.2015.05.046
7561  Takaaki Arahira, Mitsugu Todo.  Effects of osteoblast-like cell seeding on the mechanical properties of porous composite scaffolds.  Advanced Composite Materials  2015  24:79-90    DOI: 10.1080/09243046.2014.942942
7577  Yun Kee Jo, Bong-Hyuk Choi, Cong Zhou, Jin-Soo Ahn, Sang Ho Jun, Hyung Joon Cha  Bioengineered mussel glue incorporated with a cell recognition motif as an osteostimulating bone adhesive for titanium implants.  J Mater Chem B.  2015  3:8102-8114  PubMed ID: 32262867   DOI: 10.1039/c5tb01230a
7582  Masuda E, Shirai K, Maekubo K, Hirai Y.  A newly established culture method highlights regulatory roles of retinoic acid on morphogenesis and calcification of mammalian limb cartilage.  BioTechniques  2015  58:318-24  PubMed ID: 26054768   DOI: 10.2144/000114300
6618  Kim H, Tabata A, Tomoyasu T, Ueno T, Uchiyama S, Yuasa K, Tsuji A, Nagamune H.  Estrogen stimuli promote osteoblastic differentiation via the subtilisin-like proprotein convertase PACE4 in MC3T3-E1 cells.  J Bone Miner Metab  2015  33(1):30-9  PubMed ID: 24557631   DOI: 10.1007/s00774-014-0567-9
9146  Tadashi Goto, Keitaro Hagiwara, Nobuaki Shirai, Kaoru Yoshida, Hiromi Hagiwara  Apigenin Inhibits Osteoblastogenesis and Osteoclastogenesis and Prevents Bone Loss in Ovariectomized Mice  Cytotechnology  2015  67 (2), 357-65  PubMed ID: 24500394   DOI: 10.1007/s10616-014-9694-3
9188  Andy T H Wu 1, Teruo Aoki, Megumu Sakoda, Seiichi Ohta, Shigetoshi Ichimura, Taichi Ito, Takashi Ushida, Katsuko S Furukawa  Enhancing Osteogenic Differentiation of MC3T3-E1 Cells by Immobilizing Inorganic Polyphosphate Onto Hyaluronic Acid Hydrogel  Biomacromolecules  2015  16(1):166-73  PubMed ID: 25423088   DOI: 10.1021/bm501356c
9197  Soichiro Manaka, Natsuko Tanabe, Taro Kariya, Masako Naito, Tadahiro Takayama, Mayu Nagao 1, Di Liu, Koichi Ito, Masao Maeno, Naoto Suzuki, Masashi Miyazaki  Low-intensity Pulsed Ultrasound-Induced ATP Increases Bone Formation via the P2X7 Receptor in Osteoblast-Like MC3T3-E1 Cells  FEBS Lett   2015  589(3):310-8  PubMed ID: 25542352   DOI: 10.1016/j.febslet.2014.12.013
9232  Takayuki Umezawa, Peng Chen, Yusuke Tsutsumi, Hisashi Doi, Maki Ashida, Shoichi Suzuki, Keiji Moriyama, Takao Hanawa  Calcification of MC3T3-E1 Cells on Titanium and Zirconium  Dent Mater J  2015  34(5):713-8  PubMed ID: 26438997   DOI: 10.4012/dmj.2015-018
9245  Anupama R Rajapakshe, Katarzyna A Podyma-Inoue, Kazue Terasawa, Katsuya Hasegawa, Toshimitsu Namba, Yasuhiro Kumei, Masaki Yanagishita, Miki Hara-Yokoyama  Lysosome-associated Membrane Proteins (LAMPs) Regulate Intracellular Positioning of Mitochondria in MC3T3-E1 Cells  Exp Cell Res  2015  331(1):211-22  PubMed ID: 25246127   DOI: 10.1016/j.yexcr.2014.09.014
9365  Akio Watanabe, Momochika Kumagai, Takashi Mishima, Junya Ito, Yurika Otoki, Teppei Harada, Tsuyoshi Kato, Mikihiko Yoshida, Misora Suzuki, Izumi Yoshida, Kazuhiro Fujita, Masatoshi Watai, Kiyotaka Nakagawa, Teruo Miyazawa  Toddaculin, Isolated From of Toddalia Asiatica (L.) Lam., Inhibited Osteoclastogenesis in RAW 264 Cells and Enhanced Osteoblastogenesis in MC3T3-E1 Cells  PLoS One  2015  10(5):e0127158  PubMed ID: 25993011   DOI: 10.1371/journal.pone.0127158
9366  Norika Tsuchiya, Daisuke Kodama, Shigemi Goto, Akifumi Togari  Shear Stress-Induced Ca(2+) Elevation Is Mediated by Autocrine-Acting Glutamate in Osteoblastic MC3T3-E1 Cells  J Pharmacol Sci   2015  127(3):311-8  PubMed ID: 25837928   DOI: 10.1016/j.jphs.2015.01.005
9367  Yoko Karasawa, Hideki Tanaka, Kumiko Nakai, Natsuko Tanabe, Takayuki Kawato, Masao Maeno, Noriyoshi Shimizu  Tension Force Downregulates Matrix Metalloproteinase Expression and Upregulates the Expression of Their Inhibitors Through MAPK Signaling Pathways in MC3T3-E1 Cells  Int J Med Sci   2015  12(11):905-13  PubMed ID: 26640410   DOI: 10.7150/ijms.13263
9368  Koichi IMAI, Tsubasa SHIRAI, Hiroki ISHIKAWA, Yoshitomo HONDA, Muneyasu SHIDA, Fumiya OGAWA, Hirofumi SAWAI, Tadashi OHKUBO, Tatsuro MIYAKE, Fumio WATARI  Preliminary Experimental Study by the Cell Differentiation and a Cell Viability on the Cell Culture Environment with the Linear Structures of Nylon Fiber Bundles  Nano Biomedicine  2015  7:5-10    DOI: 10.11344/nano.7.5
9369  Hirom iHagiwara, Roshan Basnet, Sundari I.Wiyasihati, Kyoko Nakata, Keitaro Hagiwara, Hitoshi Miyazaki, Kaoru Yoshida  Carnosic acid inhibits the formation of osteoclasts through attenuation of expression of RANKL  PharmaNutrition  2015  3:1-6    DOI: 10.1016/j.phanu.2014.11.003
9370  Sherman Salim, Maretaningtias Dwi Ariani  In Vitro and in Vivo Evaluation of Carbonate Apatite-Collagen Scaffolds With Some Cytokines for Bone Tissue Engineering  J Indian Prosthodont Soc  2015  15(4):349-55  PubMed ID: 26929539   DOI: 10.4103/0972-4052.171821
9371  Kahoru Takeda, Haruaki Kitagawa, Ririko Tsuboi, Wakako Kiba, Jun-Ichi Sasaki, Mikako Hayashi, Satoshi Imazato  Effectiveness of Non-Biodegradable poly(2-hydroxyethyl Methacrylate)-Based Hydrogel Particles as a Fibroblast Growth factor-2 Releasing Carrier  Dent Mater  2015  31(11):1406-14  PubMed ID: 26411646   DOI: 10.1016/
9372  Takao Hirai, Kenjiro Tanaka 2, Akifumi Togari 1  α1B-Adrenergic Receptor Signaling Controls Circadian Expression of Tnfrsf11b by Regulating Clock Genes in Osteoblasts  Biol Open  2015  4(11):1400-9  PubMed ID: 26453621   DOI: 10.1242/bio.012617
9373  Hee Young Yoo, Young Hoon Song, Jeong Hyun Seo, Hyung Joon Cha & Dong Soo Hwang  Recombinant mussel coating protein fused with cell adhesion recognition motif enhanced cell proliferation  Biotechnology and Bioprocess Engineering  2015  20:211–217    DOI: 10.1007/s12257-014-0621-4
9375  Gyeung Mi Seon , Hyok Jin Seo, Soon Young Kwon, Mi Hee Lee, Byeong-Ju Kwon, Min Sung Kim, Min-Ah Koo, Bong Joo Park, Jong-Chul Park  Titanium Surface Modification by Using Microwave-Induced Argon Plasma in Various Conditions to Enhance Osteoblast Biocompatibility  Biomater Res  2015  19:13  PubMed ID: 26331083   DOI: 10.1186/s40824-015-0034-2
9378  R Toita, Sunarso, A N Rashid, K Tsuru, K Ishikawa  Modulation of the Osteoconductive Property and Immune Response of Poly(ether Ether Ketone) by Modification With Calcium Ions  J Mater Chem B  2015  3(44):8738-8746  PubMed ID: 32262731   DOI: 10.1039/c5tb01679g
9380  Chunrong Yang, Cong Fang a b   Microporous Nano-hydroxyapatite/collagen/phosphatidylserine Scaffolds Embedding Collagen Microparticles for Controlled Drug Delivery in Bone Tissue Engineering  Materials Research  2015  18    DOI: 10.1590/1516-1439.042115
9381  Clarisse Ribeiro, Vitor Sencadas, Anabela C Areias, F Miguel Gama, Senentxu Lanceros-Méndez  Surface Roughness Dependent Osteoblast and Fibroblast Response on poly(L-lactide) Films and Electrospun Membranes  J Biomed Mater Res A  2015  103(7):2260-8  PubMed ID: 25370449   DOI: 10.1002/jbm.a.35367
9382  Bong-Hyuk Choi, Hogyun Cheong, Jin-Soo Ahn, Cong Zhou, Jong Jin Kwon, Hyung Joon Cha, Sang Ho Jun  Engineered Mussel Bioglue as a Functional Osteoinductive Binder for Grafting of Bone Substitute Particles to Accelerate in Vivo Bone Regeneration  J Mater Chem B  2015  3(4):546-555  PubMed ID: 32262336   DOI: 10.1039/c4tb01197j
9383  M Hiasa, J Teramachi , A Oda, R Amachi, T Harada, S Nakamura, H Miki, S Fujii, K Kagawa, K Watanabe, I Endo, Y Kuroda, T Yoneda, D Tsuji, M Nakao, E Tanaka, K Hamada, S Sano, K Itoh, T Matsumoto, M Abe  Pim-2 Kinase Is an Important Target of Treatment for Tumor Progression and Bone Loss in Myeloma  Leukemia  2015  29(1):207-17  PubMed ID: 24787487   DOI: 10.1038/leu.2014.147
9384  Kazi Anisur Rahman, Gulsan Ara Sathi, Hiroaki Taketa, Mahmoud Farahat, Masahiro Okada, Yasuhiro Torii, and Takuya Matsumoto  Novel 3D-Printed Device for the Simple Preparation of Hydrogel Beads  3D Printing and Additive Manufacturing  2015  2    DOI: 10.1089/3dp.2014.0023
9385  Ekavianty Prajatelistia Chanoong Lim Dongyeop X. Oh Sang Ho Jun Dong Soo Hwang  Chitosan and hydroxyapatite composite cross‐linked by dopamine has improved anisotropic hydroxyapatite growth and wet mechanical properties  Eng Life Sci  2015  15: 254-261    DOI: 10.1002/elsc.201400194
9386  Erika NISHIDA, Hirofumi MIYAJI, Junko UMEDA, Katsuyoshi KONDOH, Hiroko TAKITA, Izumi KANAYAMA, Saori TANAKA, Akihito KATO, Bunshi FUGETSU, Tsukasa AKASAKA, Masamitsu KAWANAMI  Biological Response to Nanostructure of Carbon Nanotube/titanium Composite Surfaces  Nano Biomedicine  2015  7:11-20    DOI: 10.11344/nano.7.11
9387  Takayuki Yamada, Yoichi Ezura, Tadayoshi Hayata, Shuichi Moriya, Jumpei Shirakawa, Takuya Notomi, Smriti Arayal, Makiri Kawasaki, Yayoi Izu, Kiyoshi Harada, Masaki Noda  β₂ Adrenergic Receptor Activation Suppresses Bone Morphogenetic Protein (BMP)-induced Alkaline Phosphatase Expression in Osteoblast-Like MC3T3E1 Cells  J Cell Biochem  2015  116(6):1144-52  PubMed ID: 25536656   DOI: 10.1002/jcb.25071
9388  Sho Miyamoto, Yoichi Miyamoto, Yo Shibata, Kentaro Yoshimura, Eri Izumida, Hiroaki Suzuki, Takashi Miyazaki, Koutaro Maki, Ryutaro Kamijo  In Situ Quasi-Static and Dynamic Nanoindentation Tests on Calcified Nodules Formed by Osteoblasts: Implication of Glucocorticoids Responsible for Osteoblast Calcification  Acta Biomater  2015  12:216-226  PubMed ID: 25448350   DOI: 10.1016/j.actbio.2014.10.038
9389  Hyun-Seok Jin, Jeonghyun Kim, Sangwook Park, Eunkuk Park, Bo-Young Kim, Vit-Na Choi, Young-Hyun Yoo, Bom-Taeck Kim, Seon-Yong Jeong  Association of the I264T Variant in the Sulfide Quinone Reductase-Like (SQRDL) Gene With Osteoporosis in Korean Postmenopausal Women  PLoS One  2015  10(8):e0135285  PubMed ID: 26258864   DOI: 10.1371/journal.pone.0135285
9390  Takuya Notomi, Miyuki Kuno, Akiko Hiyama, Yoichi Ezura, Masashi Honma, Toru Ishizuka, Kiyoshi Ohura, Hiromu Yawo, Masaki Noda  Membrane Depolarization Regulates Intracellular RANKL Transport in Non-Excitable Osteoblasts  Bone  2015  81:306-314  PubMed ID: 26211991   DOI: 10.1016/j.bone.2015.07.031
9392  Masahiko Terauchi, Go Ikeda, Kei Nishida, Atsushi Tamura, Satoshi Yamaguchi, Kiyoshi Harada, Nobuhiko Yui  Supramolecular Polyelectrolyte Complexes of Bone Morphogenetic Protein-2 With Sulfonated Polyrotaxanes to Induce Enhanced Osteogenic Differentiation  Macromol Biosci  2015  15(7):953-64  PubMed ID: 25810046   DOI: 10.1002/mabi.201500032
9393  Terukazu Sanui, Urara Tanaka, Takao Fukuda, Kyosuke Toyoda, Takaharu Taketomi, Ryo Atomura, Kensuke Yamamichi, Fusanori Nishimura  Mutation of Spry2 Induces Proliferation and Differentiation of Osteoblasts but Inhibits Proliferation of Gingival Epithelial Cells  J Cell Biochem  2015  116(4):628-39  PubMed ID: 25399781   DOI: 10.1002/jcb.25014
9395  Işıl Gerçek Beşkardeş, Tuğrul Tolga Demirtaş, Müge Dağlı Durukan, Menemşe Gümüşderelioğlu  Microwave-assisted Fabrication of Chitosan-Hydroxyapatite Superporous Hydrogel Composites as Bone Scaffolds  J Tissue Eng Regen Med  2015  9(11):1233-46  PubMed ID: 23239627   DOI: 10.1002/term.1677
9396  Naoko Hase, Nobuaki Ozeki, Taiki Hiyama, Hideyuki Yamaguchi, Rie Kawai, Ayami Kondo, Kazuhiko Nakata, Makio Mogi  Products of Dentin Matrix protein-1 Degradation by interleukin-1β-induced Matrix metalloproteinase-3 Promote Proliferation of Odontoblastic Cells  Biosci Trends  2015  ;9(4):228-36  PubMed ID: 26355224   DOI: 10.5582/bst.2015.01092
9397  Shoichi Kaneshiro, Kosuke Ebina, Kenrin Shi, Kiyoshi Yoshida, Dai Otsuki, Hideki Yoshikawa, Chikahisa Higuchi  Bruton Tyrosine Kinase (Btk) Suppresses Osteoblastic Differentiation  J Bone Miner Metab  2015  33(5):486-95  PubMed ID: 25230818   DOI: 10.1007/s00774-014-0612-8
9399  Koji Mizuhashi, Taro Chaya, Takashi Kanamoto, Yoshihiro Omori, Takahisa Furukawa  Obif, a Transmembrane Protein, Is Required for Bone Mineralization and Spermatogenesis in Mice  PLoS Onec  2015  10(7):e0133704  PubMed ID: 26207632   DOI: 10.1371/journal.pone.0133704
9403  Drago Skrtic, Joseph M. Antonucci  Dental Composites: Bioactive Polymeric Amorphous Calcium Phosphate-Based  Encyclopedia of Biomedical Polymers and Polymeric Biomaterials  2015  2443    DOI: 10.1081/E-EBPP-120051063
9374  Taro Kariya, Natsuko Tanabe, Chieko Shionome, Soichiro Manaka, Takayuki Kawato, Ning Zhao, Masao Maeno, Naoto Suzuki, Noriyoshi Shimizu  Tension Force-Induced ATP Promotes Osteogenesis Through P2X7 Receptor in Osteoblasts  J Cell Biochem   2015  116(1):12-21  PubMed ID: 24905552   DOI: 10.1002/jcb.24863
9405  Yoshikazu Mikami, Kiyofumi Yamamoto, Yuko Akiyama, Masayuki Kobayashi, Eri Watanabe, Nobukazu Watanabe, Masatake Asano, Noriyoshi Shimizu, Kazuo Komiyama  Osteogenic Gene Transcription Is Regulated via Gap Junction-Mediated Cell-Cell Communication  Stem Cells Dev  2015  24(2):214-27  PubMed ID: 25137151   DOI: 10.1089/scd.2014.0060
10322  Ryo Nishikiori, Kotaro Watanabe, Koichi Kato  Antibody Arrays for Quality Control of Mesenchymal Stem Cells  ACS Appl Mater Interfaces  2015  7(30):16828-36  PubMed ID: 26172315   DOI: 10.1021/acsami.5b04860
12560  Eto S, Miyamoto H, Shobuike T, Noda I, Akiyama T, Tsukamoto M, Ueno M, Someya S, Kawano S, Sonohata M, Mawatari M.  Silver oxide-containing hydroxyapatite coating supports osteoblast function and enhances implant anchorage strength in rat femur  J Orthop Res  2015  33(9):1391-7.  PubMed ID: 25808232   DOI: 10.1002/jor.22903
14966  Atsushi Horiguchi, Toshihiko Shiraishi  Study on a Cell Mechanosensing System by Measuring Structural Deformation and Biochemical Response  Biomedical and Biotechnology Engineering  2015  3    DOI: 10.1115/imece2015-51456
15038  Ivashchenko S, Escobar Ivirico JL, García Cruz DM, Campillo-Fernández A, Gallego Ferrer G, Monleón Pradas M.  Bioactive organic-inorganic poly(CLMA-co-HEA)/silica nanocomposites  J Biomater Appl  2015  29(8):1096-10  PubMed ID: 25294191   DOI: 10.1177/0885328214554816
15218  Maeda Y, Sekiguchi F, Yamanaka R, Sugimoto R, Yamasoba D, Tomita S, Nishikawa H, Kawabata A.  Mechanisms for proteinase-activated receptor 1-triggered prostaglandin E2 generation in mouse osteoblastic MC3T3-E1 cells  Biol Chem  2015  396(2):153-62  PubMed ID: 25205726   DOI: 10.1515/hsz-2014-0148
15185  Tomohiro Fukuno, Toshihiko Shiraishi  Effects of Cyclic Strain at Focal Adhesions on Migration of an Osteoblast  Volume 3: Biomedical and Biotechnology Engineering  2015      DOI: 10.1115/imece2015-51447
17411  Zhou X, Park SH, Mao H, Isoshima T, Wang Y, Ito Y.  Nanolayer formation on titanium by phosphonated gelatin for cell adhesion and growth enhancement  Int J Nanomedicine  2015  10:5597-607  PubMed ID: 26366080   DOI: 10.2147/IJN.S82166
3517  Kosaka T, Fukui R, Matsui M, Kurosaka Y, Nishimura H, Tanabe M, Takakura Y, Iwai K, Waki T, Fujita T.  RAGE, receptor of advanced glycation endoproducts, negatively regulates chondrocytes differentiation.  PLoS One  2014  9(9):e108819  PubMed ID: 25275461   DOI: 10.1371/journal.pone.0108819
6607  Nakazato R, Takarada T, Watanabe T, Nguyen BT, Ikeno S, Hinoi E, Yoneda Y.  Constitutive and functional expression of runt-related transcription factor-2 by microglial cells.  Neurochem Int  2014  74:24-35  PubMed ID: 24768841   DOI: 10.1016/j.neuint.2014.04.010
6609  Yang YJ, Kwon Y, Choi BH, Jung D, Seo JH, Lee KH, Cha HJ.  Multifunctional adhesive silk fibroin with blending of RGD-bioconjugated mussel adhesive protein.  Biomacromolecules  2014  15(4):1390-8  PubMed ID: 24601579   DOI: 10.1021/bm500001n
6611  Lin YY, Chen CY, Chuang TY, Lin Y, Liu HY, Mersmann HJ, Wu SC, Ding ST.  Adiponectin receptor 1 regulates bone formation and osteoblast differentiation by GSK-3β/β-catenin signaling in mice.  Bone  2014  64:147-54  PubMed ID: 24713193   DOI: 10.1016/j.bone.2014.03.051
9294  Yaqiong Yu, Di Yang, Lihong Qiu, Hirohiko Okamura, Jiajie Guo, Tatsuji Haneji  Tumor Necrosis Factor-α Induces interleukin-34 Expression Through Nuclear factor‑κB Activation in MC3T3-E1 Osteoblastic Cells  Mol Med Rep  2014  10(3):1371-6  PubMed ID: 24970360   DOI: 10.3892/mmr.2014.2353
9295  Eiichi Suzuki, Hiromi Ochiai-Shino, Hideto Aoki, Shoko Onodera, Akiko Saito, Atsushi Saito, Toshifumi Azuma  Akt Activation Is Required for TGF-β1-induced Osteoblast Differentiation of MC3T3-E1 Pre-Osteoblasts  PLoS One  2014  9(12):e112566  PubMed ID: 25470129   DOI: 10.1371/journal.pone.0112566
9296  Naofumi Ohtsu, Mitsuhiro Hirano, Hirofumi Arai  Response of Osteoblast-Like MC3T3-E1 Cells on Bioactive Titanium Fabricated by a Chemical Treatment Process Using a Calcium-Phosphate Slurry  J Biomed Mater Res A  2014  102(11):3838-45  PubMed ID: 24307316   DOI: 10.1002/jbm.a.35053
9297  Chihiro Mochizuki, Hiroki Hara, Kei Oya, Shun Aoki, Tohru Hayakawa, Hiromichi Fujie, Mitsunobu Sato  Behaviors of MC3T3-E1 Cells on Carbonated Apatite Films, With a Characteristic Network Structure, Fabricated on a Titanium Plate by Aqueous Spray Coating  Mater Sci Eng C Mater Biol Appl  2014  39:245-52  PubMed ID: 24863222   DOI: 10.1016/j.msec.2014.02.040
9298  Emina Aoyama, Ippei Watari 1, Katarzyna Anna Podyma-Inoue 2, Masaki Yanagishita 2, Takashi Ono 1  Expression of Glucagon-Like peptide-1 Receptor and Glucose‑dependent Insulinotropic Polypeptide Receptor Is Regulated by the Glucose Concentration in Mouse Osteoblastic MC3T3-E1 Cells  Int J Mol Med  2014  34(2):475-82  PubMed ID: 24866833   DOI: 10.3892/ijmm.2014.1787
9299  Muhammad Hanif Siddiqi, Muhammad Zubair Siddiqi, Sungeun Ahn, Sera Kang, Yeon-Ju Kim, Karpagam Veerappan, Dong-Uk Yang, Deok-Chun Yang  Stimulative Effect of Ginsenosides Rg5:Rk1 on Murine Osteoblastic MC3T3-E1 Cells  Phytother Res  2014  28(10):1447-55  PubMed ID: 24643957   DOI: 10.1002/ptr.5146
9300  Yoko Nakamura, Ai Hasebe, Kaneyoshi Takahashi, Masumi Iijima, Nobuo Yoshimoto, Andrés D Maturana, Kang Ting, Shun'ichi Kuroda, Tomoaki Niimi  Oligomerization-induced Conformational Change in the C-terminal Region of Nel-like Molecule 1 (NELL1) Protein Is Necessary for the Efficient Mediation of Murine MC3T3-E1 Cell Adhesion and Spreading  J Biol Chem  2014  289(14):9781-94  PubMed ID: 24563467   DOI: 10.1074/jbc.M113.507020
9301  Chethala N Vishnuprasad 1, Tomoko Tsuchiya 2, Shiro Kanegasaki 1, Joon Ho Kim 1, Sung Soo Han 1  Aurantio-obtusin Stimulates Chemotactic Migration and Differentiation of MC3T3-E1 Osteoblast Cells  Planta Med  2014  80(7):544-9  PubMed ID: 24841966   DOI: 10.1055/s-0034-1368445
9302  Eun Mi Choi  Sunflower seed extract enhances the differentiation of osteoblastic MC3T3-E1 cells  Food and Agricultural Immunology  2014  25:9-19    DOI: 10.1080/09540105.2012.716399
9303  Kyung-Mi Chang, Eun-Mi Choi & Gun-Hee Kim  Effects of medicinal plant Atractylodes japonica on MC3T3-E1 cells  Food Science and Biotechnology  2014  23:1173–1176    DOI: 10.1007/s10068-014-0160-y
9304  Kaori Tsutsumi, Nagahito Saito, Yumi Kawazoe, Hong-Kean Ooi, Toshikazu Shiba  Morphogenetic Study on the Maturation of Osteoblastic Cell as Induced by Inorganic Polyphosphate  PLoS One  2014  9(2):e86834  PubMed ID: 24498284   DOI: 10.1371/journal.pone.0086834
9305  Miki Nakamura-Ota, Ryoji Hamanaka, Hiroyuki Yano, Sawako Adachi, Hideaki Sumiyoshi, Noritaka Matsuo, Hidekatsu Yoshioka  A New Murine Osteoblastic Cell Line Immortalized With the SV40 Large T Antigen  Cell Tissue Bank  2014  15(3):373-80  PubMed ID: 23974965   DOI: 10.1007/s10561-013-9394-9
9306  Naofumi Ohtsu, Toyofumi Takahara, Mitsuhiro Hirano, Hirofumi Arai  Effect of treatment temperature on the biocompatibility and mechanical strength of hydroxyapatite coating formed on titanium using calcium phosphate slurry  Surface and Coatings Technology  2014  239:185-190    DOI: 10.1016/j.surfcoat.2013.11.038
9307  Dajana Milovac, Tatiana C Gamboa-Martínez, Marica Ivankovic, Gloria Gallego Ferrer, Hrvoje Ivankovic  PCL-coated Hydroxyapatite Scaffold Derived From Cuttlefish Bone: In Vitro Cell Culture Studies  Mater Sci Eng C Mater Biol Appl  2014  42:264-72  PubMed ID: 25063118   DOI: 10.1016/j.msec.2014.05.034
9308  Mitsuhiro Hirano, Taro Kozuka, Yuta Asano, Yuko Kakuchi, Hirofumi Arai, Naofumi Ohtsu  Effect of sterilization and water rinsing on cell adhesion to titanium surfaces  Applied Surface Science  2014  311:498-502    DOI: 10.1016/j.apsusc.2014.05.096
9309  Takao Hirai, Kenjiro Tanaka, Akifumi Togari  β-Adrenergic Receptor Signaling Regulates Ptgs2 by Driving Circadian Gene Expression in Osteoblasts  J Cell Sci  2014  127(Pt 17):3711-9  PubMed ID: 24994935   DOI: 10.1242/jcs.148148
9310  Erika Nishida, Hirofumi Miyaji, Hiroko Takita, Izumi Kanayama, Maiko Tsuji, Tsukasa Akasaka, Tsutomu Sugaya, Ryuji Sakagami and Masamitsu Kawanami  Graphene oxide coating facilitates the bioactivity of scaffold material for tissue engineering  Japanese Journal of Applied Physics  2014  53:06JD04   
9311  Meiko Tachikake-Kuramoto, Junji Suzuki, Yurong Wangb Chieko Mitsuhata, Katsuyuki Kozai  Lipopolysaccharide derived from Aggregatibacter actinomycetemcomitans inhibits differentiation of osteoblasts  Pediatric Dental Journal  2014  24:83-88    DOI: 10.1016/j.pdj.2014.03.004
9312  Geunseon Ahn, Yunna Kim, Sang-Won Lee, Yoon Jeong Jeong, Hyungbin Son & Donghyun Lee  Effect of heterogeneous multi-layered gelatin scaffolds on the diffusion characteristics and cellular activities of preosteoblasts  Macromolecular Research  2014  22:99–107    DOI: 10.1007/s13233-014-2024-y
9313  Naofumi Ohtsu, Wataru Saito, Misao Yamane  Selectable surface nitridation of titanium using focused pulsed Nd: YAG laser irradiation with nitrogen gas blow  Surface and Coatings Technology  2014  246:52-56    DOI: 10.1016/j.surfcoat.2014.02.068
9314  D. M. Correiaab, R. Gonçalvesab, C. Ribeiroac, V. Sencadasad, G. Botelhob, J. L. Gomez Ribellesef and S. Lanceros-Méndez  Electrosprayed poly (vinylidene fluoride) microparticles for tissue engineering applications  RSC Adv  2014  4:33013-33021    DOI: 10.1039/C4RA04581E
9315  Takao Hirai, Kenjiro Tanaka, Akifumi Togari  α1-adrenergic Receptor Signaling in Osteoblasts Regulates Clock Genes and Bone Morphogenetic Protein 4 Expression Through Up-Regulation of the Transcriptional Factor Nuclear Factor IL-3 (Nfil3)/E4 Promoter-Binding Protein 4 (E4BP4)  J Biol Chem  2014  289(24):17174-83  PubMed ID: 24794868   DOI: 10.1074/jbc.M113.546135
9316  Izumi Kanayama, Hirofumi Miyaji, Hiroko Takita, Erika Nishida, Maiko Tsuji, Bunshi Fugetsu, Ling Sun, Kana Inoue, Asako Ibara, Tsukasa Akasaka, Tsutomu Sugaya, Masamitsu Kawanami   Comparative Study of Bioactivity of Collagen Scaffolds Coated With Graphene Oxide and Reduced Graphene Oxide  Int J Nanomedicine  2014  9:3363-73  PubMed ID: 25050063   DOI: 10.2147/IJN.S62342
9317  Daniela M. Correia Clarisse Ribeiro José C.C. Ferreira Gabriela Botelho José Luis Gomez Ribelles Senentxu Lanceros‐Méndez Vitor Sencadas  Influence of electrospinning parameters on poly (hydroxybutyrate) electrospun membranes fiber size and distribution  Advanced Science  2014  54:1608-1617    DOI: 10.1002/pen.23704
9318  Shoichi Kaneshiro, Kosuke Ebina, Kenrin Shi, Chikahisa Higuchi, Makoto Hirao, Michio Okamoto, Kota Koizumi, Tokimitsu Morimoto, Hideki Yoshikawa, Jun Hashimoto  IL-6 Negatively Regulates Osteoblast Differentiation Through the SHP2/MEK2 and SHP2/Akt2 Pathways in Vitro  J Bone Miner Metab  2014  32(4):378-92  PubMed ID: 24122251   DOI: 10.1007/s00774-013-0514-1
9319  Keiko Kaneko, Chikahisa Higuchi 1, Norifumi Naka 1, Hideki Yoshikawa  Expression of Noggin, an Antagonist of Bone Morphogenetic Protein, in Schwannoma: A Possible Mechanism  Oncol Lett  2014  8(1):111-116  PubMed ID: 24959229   DOI: 10.3892/ol.2014.2138
9320  Yuko Akiyama, Yoshikazu Mikami, Eri Watanabe, Nobukazu Watanabe, Taku Toriumi, Tomihisa Takahashi, Kazuo Komiyama, Keitaro Isokawa, Noriyoshi Shimizu, Masaki J Honda  The P75 Neurotrophin Receptor Regulates Proliferation of the Human MG63 Osteoblast Cell Line  Differentiation  2014  87(3-4):111-8  PubMed ID: 24582280   DOI: 10.1016/j.diff.2014.01.002
9321  Juna Nakao, Yasuyuki Fujii, Joji Kusuyama, Kenjiro Bandow, Kyoko Kakimoto, Tomokazu Ohnishi, Tetsuya Matsuguchi  Low-intensity Pulsed Ultrasound (LIPUS) Inhibits LPS-induced Inflammatory Responses of Osteoblasts Through TLR4-MyD88 Dissociation  Bone  2014  58:17-25  PubMed ID: 24091132   DOI: 10.1016/j.bone.2013.09.018
9322  Tomohiro Itoh, Masahiro Nakamura, Hirohisa Nakamichi, Masashi Ando, Yasuyuki Tsukamasa, Yukio Furuichi  Regulation of the Differentiation of Osteoblasts and Osteoclasts by a Hot-Water Extract of Adzuki Beans (Vigna Angularis)  Biosci Biotechnol Biochem  2014  78(1):92-9  PubMed ID: 25036490   DOI: 10.1080/09168451.2014.877182
9323  Ran Zhao, Masayoshi Kamon, Kazuichi Sakamoto  (–)-Epigallocatechingallate Interferes RANKL/RANK Signal Pathway and Induces Apoptosis during Osteoclastogenesis in RAW264 Cell  Food and Nutrition Sciences  2014  5:107-116    DOI: 10.4236/fns.2014.52014
9324  Nobuaki Ozeki, Rie Kawai, Hideyuki Yamaguchi, Taiki Hiyama, Katsue Kinoshita, Naoko Hase, Kazuhiko Nakata, Ayami Kondo, Makio Mogi, Hiroshi Nakamura  IL-1β-induced Matrix metalloproteinase-13 Is Activated by a Disintegrin and metalloprotease-28-regulated Proliferation of Human Osteoblast-Like Cells  Exp Cell Res  2014  ;323(1):165-77  PubMed ID: 24613731   DOI: 10.1016/j.yexcr.2014.02.018
9325  Hany Mohamed Khattab, Mitsuaki Ono, Wataru Sonoyama, Yasutaka Oida, Shigehiko Shinkawa, Yuya Yoshioka, Kenji Maekawa, Yasuhiko Tabata, Kazushige Sugama, Walter Sebald, Takuo Kuboki  The BMP2 Antagonist Inhibitor L51P Enhances the Osteogenic Potential of BMP2 by Simultaneous and Delayed Synergism  Bone  2014  69:165-73  PubMed ID: 25240457   DOI: 10.1016/j.bone.2014.09.011
9326  A. C. Lopes, C. Ribeiro, V. Sencadas, G. Botelho & S. Lanceros-Méndez  Effect of filler content on morphology and physical–chemical characteristics of poly (vinylidene fluoride)/NaY zeolite-filled membranes  Journal of Materials Science  2014  49:3361–3370    DOI: 10.1007/s10853-014-8043-4
9327  Tsai-Ching Yang, Hui-Ying Shu, Hsien-Te Chen, Chi-Jen Chung, Ju-LiangH  Interface between grown osteoblast and micro-arc oxidized bioactive layers  Surface and Coatings Technology  2014  259:185-192    DOI: 10.1016/j.surfcoat.2014.04.002
9328  Byeong-Ju Kwon, Mi Hee Lee, Min-Ah Koo, Jae-Jin Han, Jong-Chul Park  Ethyl-3,4-dihydroxybenzoate With a Dual Function of Induction of Osteogenic Differentiation and Inhibition of Osteoclast Differentiation for Bone Tissue Engineering  Tissue Eng Part A  2014  20(21-22):2975-84  PubMed ID: 24784993   DOI: 10.1089/ten.TEA.2013.0567
9330  Xin Li, Jamie Garcia, Jinxiu Lu, Sidney Iriana, Ivo Kalajzic, David Rowe, Linda L Demer, Yin Tintut  Roles of Parathyroid Hormone (PTH) Receptor and Reactive Oxygen Species in Hyperlipidemia-Induced PTH Resistance in Preosteoblasts  J Cell Biochem  2014  115(1):179-88  PubMed ID: 24038594   DOI: 10.1002/jcb.24648
9331  Masanobu Kamitakahara, Yuika Uno, Koji Ioku  Behavior of Osteoblast-Like Cells on Calcium-Deficient Hydroxyapatite Ceramics Composed of Particles With Different Shapes and Sizes  J Mater Sci Mater Med  2014  25(1):239-45  PubMed ID: 24101185   DOI: 10.1007/s10856-013-5063-6
9332  Joji Kusuyama, Kenjiro Bandow, Mitsuo Shamoto, Kyoko Kakimoto, Tomokazu Ohnishi, Tetsuya Matsuguchi  Low Intensity Pulsed Ultrasound (LIPUS) Influences the Multilineage Differentiation of Mesenchymal Stem and Progenitor Cell Lines Through ROCK-Cot/Tpl2-MEK-ERK Signaling Pathway  J Biol Chem  2014  289(15):10330-44  PubMed ID: 24550383   DOI: 10.1074/jbc.M113.546382
9333  Yun Kee Jo, Jeong Hyun Seo, Bong-Hyuk Choi, Bum Jin Kim, Hwa Hui Shin, Byeong Hee Hwang, Hyung Joon Cha  Surface-independent Antibacterial Coating Using Silver Nanoparticle-Generating Engineered Mussel Glue  ACS Appl Mater Interfaces  2014  6(22):20242-53  PubMed ID: 25311392   DOI: 10.1021/am505784k
9334  Tetsuro Ohba, Heather A Cole, Justin M M Cates, David A Slosky, Hirotaka Haro, Takashi Ando, Herbert S Schwartz, Jonathan G Schoenecker  Bisphosphonates Inhibit Osteosarcoma-Mediated Osteolysis via Attenuation of Tumor Expression of MCP-1 and RANKL  J Bone Miner Res  2014  29(6):1431-45  PubMed ID: 24443409   DOI: 10.1002/jbmr.2182
9335  Takuya Notomi, Ikuaki Karasaki, Yuichi Okazaki, Nobukazu Okimoto, Yushi Kato, Kiyoshi Ohura, Masaki Noda, Toshitaka Nakamura, Masashige Suzuki  Insulinogenic Sucrose+amino Acid Mixture Ingestion Immediately After Resistance Exercise Has an Anabolic Effect on Bone Compared With Non-Insulinogenic Fructose+amino Acid Mixture in Growing Rats  Bone  2014  65:42-8  PubMed ID: 24815919   DOI: 10.1016/j.bone.2014.05.002
9337  C. S. R. Silva,G. M. Luz,T. C. Gamboa-martÍnez,J. F. Mano,J. L. GÓmez ribelles &J. A. GÓmez-tejedorCenter for Biomaterials and T  Poly (ɛ-caprolactone) electrospun scaffolds filled with nanoparticles. Production and optimization according to Taguchi's methodology  Journal of Macromolecular Science, Part B   2014  53:781-799    DOI: 10.1080/00222348.2013.861304
9338  Miho Nakamura, Akira Kobayashi, Kosuke Nozaki, Naohiro Horiuchi, Akiko Nagai1, Kimihiro Yamashita  Improvement of osteoblast adhesion through polarization of plasma-sprayed hydroxyapatite coatings on metal  Journal of Medical and Biological Engineering  2014  34(1): 44-48   
9339  Nobuaki Ozeki, Makio Mogi, Hideyuki Yamaguchi, Taiki Hiyama, Rie Kawai, Naoko Hase, Kazuhiko Nakata, Hiroshi Nakamura, Randall H Kramer   Differentiation of Human Skeletal Muscle Stem Cells Into Odontoblasts Is Dependent on Induction of α1 Integrin Expression  J Biol Chem  2014  289(20):14380-91  PubMed ID: 24692545   DOI: 10.1074/jbc.M113.526772
9340  Shigeki Suzuki, Seiji Kobuke, Naoto Haruyama, Hiroaki Hoshino, Ashok B Kulkarni, Fusanori Nishimura  Adhesive and Migratory Effects of Phosphophoryn Are Modulated by Flanking Peptides of the Integrin Binding Motif  PLoS One  2014  9(11):e112490  PubMed ID: 25396425   DOI: 10.1371/journal.pone.0112490
9341  Ji-Won Lee, Akira Yamaguchi, Tadahiro Iimura  Functional Heterogeneity of Osteocytes in FGF23 Production: The Possible Involvement of DMP1 as a Direct Negative Regulator  Bonekey Rep  2014  3:543  PubMed ID: 24991406   DOI: 10.1038/bonekey.2014.38
9342  Naofumi Shiomi, Keiko Watanabe  Effects of hydrocortisone, glycerophosphate and retinol on the differentiation of mesenchymal stem cells and vascular endothelial cells to osteoblasts  Journal of Biomedical Science and Engineering  2014  7:Article ID:51519    DOI: 10.4236/jbise.2014.713103
9355  Muhammad Hanif Siddiqi, Muhammad Zubair Siddiqi, Sungeun Ahn, Yeon-Ju Kim, Deok Chun Yang  Ginsenoside Rh1 Induces Mouse Osteoblast Growth and Differentiation Through the Bone Morphogenetic Protein 2/runt-related Gene 2 Signalling Pathway  J Pharm Pharmacol  2014  66(12):1763-73  PubMed ID: 25154440   DOI: 10.1111/jphp.12306
15318  Guo J, Yang D, Okamura H, Teramachi J, Ochiai K, Qiu L, Haneji T.  Calcium hydroxide suppresses Porphyromonas endodontalis lipopolysaccharide-induced bone destruction  J Dent Res  2014  93(5):508-13  PubMed ID: 24603641   DOI: 10.1177/0022034514526886
15475  Chunrong Yang, Jianhua Wang  Preparation and characterization of collagen microspheres for sustained release of steroidal saponins  Materials Research  2014  17:1644-1650    DOI: 10.1590/1516-1439.307214
15476  Toshihiko Shiraishi, Akinori Ishii, Shin Morishita  Effects of Mechanical Vibration on Multilayering of Cultured Osteoblasts  Biomedical and Biotechnology Engineering  2014  3    DOI: 10.1115/imece2014-37731
17409  Kaneko H, Sasaki H, Honma S, Hayakawa T, Sato M, Yajima Y, Yoshinari M.  Influence of thin carbonate-containing apatite coating with molecular precursor method to   Dent Mater J  2014  33(1):39-47  PubMed ID: 24492110   DOI: 10.4012/dmj.2013-122
17410  Park E, Jin HS, Cho DY, Kim J, Kim MC, Choi CW, Jin Y, Lee JW, Park JH, Chung YS, Huh D, Jeong SY.  The effect of Lycii Radicis Cortex extract on bone formation in vitro and in vivo  Molecules  2014  19(12):19594-609  PubMed ID: 25432011   DOI: 10.3390/molecules191219594
17407  Suzaki A, Komine-Aizawa S, Hayakawa S.  Suppression of osteoblast Toll-like receptor 2 signaling by endothelin-1  J Orthop Res  2014  32(7):910-4.  PubMed ID: 24700498   DOI: 10.1002/jor.22627
7649  Watanabe K, Tsunoda K, Itoh M, Fukui M, Mori H, Hitomi K.  Transglutaminase 2 and Factor XIII catalyze distinct substrates in differentiating osteoblastic cell line: utility of highly reactive substrate peptides.  Amino Acids  2013  44:209-14  PubMed ID: 22045386   DOI: 10.1007/s00726-011-1131-8
7686  Choi EM.  Deoxyactein stimulates osteoblast function and inhibits bone-resorbing mediators in MC3T3-E1 cells.  J Appl Toxicol  2013  33:190-5  PubMed ID: 21910134   DOI: 10.1002/jat.1733
5326  Hagihara K, Fujii K, Matsugaki A, Nakano T.  Possibility of Mg- and Ca-based intermetallic compounds as new biodegradable implant materials.  Mater Sci Eng C Mater Biol Appl  2013  33(7):4101-11  PubMed ID: 23910320   DOI: 10.1016/j.msec.2013.05.055
6206  Ozeki N, Mogi M, Kawai R, Yamaguchi H, Hiyama T, Nakata K, Nakamura H.  Mouse-induced pluripotent stem cells differentiate into odontoblast-like cells with induction of altered adhesive and migratory phenotype of integrin.  PLoS One  2013  8(11):e80026  PubMed ID: 24244598   DOI: 10.1371/journal.pone.0080026
6322  Tsukamoto T, Li X, Morita H, Minowa T, Aizawa T, Hanagata N, Demura M.  Role of S-palmitoylation on IFITM5 for the interaction with FKBP11 in osteoblast cells.  PLoS One  2013  8(9):e75831  PubMed ID: 24058703   DOI: 10.1371/journal.pone.0075831
6560  Mitani K1 Haruyama N, Hatakeyama J, Igarashi K.  Amelogenin splice isoforms stimulate chondrogenic differentiation of ATDC5 cells.  Oral Dis  2013  19(2):169-79  PubMed ID: 22863294   DOI: 10.1111/j.1601-0825.2012.01967.x
6561  Morimoto H, Baba R, Haneji T, Doi Y.  Double-stranded RNA-dependent protein kinase regulates insulin-stimulated chondrogenesis in mouse clonal chondrogenic cells, ATDC-5.  Cell Tissue Res  2013  351(1):41-7  PubMed ID: 23180319   DOI: 10.1007/s00441-012-1521-6
9253  Yoshiaki Tabuchi, Yuuki Sugahara, Mika Ikegame, Nobuo Suzuki, Kei-ichiro Kitamura, Takashi Kondo  Genes Responsive to Low-Intensity Pulsed Ultrasound in MC3T3-E1 Preosteoblast Cells  Int J Mol Sci  2013  14(11):22721-40  PubMed ID: 24252911   DOI: 10.3390/ijms141122721
9255  Osamu Ishibashi   Bone Morphogenetic Protein-2 Desensitizes MC3T3-E1 Osteoblastic Cells to Estrogen Through Transcriptional Downregulation of Estrogen Receptor 1  J Bone Metab  2013  20(2):83-8  PubMed ID: 24524062   DOI: 10.11005/jbm.2013.20.2.83
9256  Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo  Micromorphological Cellular Responses of MC3T3-E1 and RAW264.7 After Exposure to Water-Dispersible Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds  Dent Mater J  2013  32(5):725-33  PubMed ID: 24088827   DOI: 10.4012/dmj.2012-203
9257  Yoshimitsu Okazaki, Emiko Gotoh  Metal Ion Effects on Different Types of Cell Line, Metal Ion Incorporation Into L929 and MC3T3-E1 Cells, and Activation of Macrophage-Like J774.1 Cells  Mater Sci Eng C Mater Biol Appl  2013  33(4):1993-2001  PubMed ID: 23498224   DOI: 10.1016/j.msec.2013.01.015
9258  Yuu Horikiri, Tsuyoshi Shimo, Naito Kurio, Tatsuo Okui, Kenichi Matsumoto, Masahiro Iwamoto, Akira Sasaki  Sonic Hedgehog Regulates Osteoblast Function by Focal Adhesion Kinase Signaling in the Process of Fracture Healing  PLoS One  2013  8(10):e76785  PubMed ID: 24124594   DOI: 10.1371/journal.pone.0076785
9259  Guy Eelen, Lieve Verlinden, Mark B Meyer, Rik Gijsbers, J Wesley Pike, Roger Bouillon, Annemieke Verstuyf  1,25-Dihydroxyvitamin D3 and the Aging-Related Forkhead Box O and Sestrin Proteins in Osteoblasts  J Steroid Biochem Mol Biol   2013  136:112-9  PubMed ID: 22989484   DOI: 10.1016/j.jsbmb.2012.09.011
9261  Lieve Verlinden, Carsten Kriebitzsch, Guy Eelen, Mark Van Camp, Carlien Leyssens, Biauw Keng Tan, Ine Beullens, Annemieke Verstuyf  The Odd-Skipped Related Genes Osr1 and Osr2 Are Induced by 1,25-dihydroxyvitamin D3  J Steroid Biochem Mol Biol  2013  136:94-7  PubMed ID: 23238298   DOI: 10.1016/j.jsbmb.2012.12.001
9262  Song Chen, Nobutaka Hanagata  Directing osteoblast alignment and elongation on the micro-grooved silica-based hybrid membrane  Advanced Materials Research  2013  647:165-169    DOI: 10.4028/
9263  Geunseon Ahn, Jae YeonLee, Dai-WuSeol, Sung Gyu Pyo, DonghyunLee   The effect of calcium phosphate cement–silica composite materials on proliferation and differentiation of pre-osteoblast cells  Materials Letters  2013  109:302-305    DOI: 10.1016/j.matlet.2013.07.110
9264  Kazuyoshi Uchihashi, Shigehisa Aoki, Aki Matsunobu, Shuji Toda  Osteoblast Migration Into Type I Collagen Gel and Differentiation to Osteocyte-Like Cells Within a Self-Produced Mineralized Matrix: A Novel System for Analyzing Differentiation From Osteoblast to Osteocyte  Bone  2013  52(1):102-10  PubMed ID: 22985890   DOI: 10.1016/j.bone.2012.09.001
9265  Yohei Hanazaki, Daisuke Ito, Kazuya Furusawa, Akimasa Fukui & Naoki Sasaki  Change in the viscoelastic properties of agarose gel by HAp precipitation by osteoblasts cultured in an agarose gel matrix  Journal of Biorheology  2013  26:21–28    DOI: 10.1007/s12573-011-0043-2
9266  R. Seda Tığlı Aydın, Baki Hazer, Merve Acar & Menemşe Gümüşderelioğlu   Osteogenic activities of polymeric soybean oil-g-polystyrene membranes  Polymer Bulletin  2013  70:2065–2082    DOI: 10.1007/s00289-013-0976-2
9267  Maretaningtias Dwi Ariani, Ayumu Matsuura, Isao Hirata, Takayasu Kubo, Koichi Kato, Yasumasa Akagawa  New Development of Carbonate Apatite-Chitosan Scaffold Based on Lyophilization Technique for Bone Tissue Engineering  Dent Mater J   2013  32(2):317-25  PubMed ID: 23538769   DOI: 10.4012/dmj.2012-257
9268  M Onishi, Y Fujita, H Yoshikawa, T Yamashita  Inhibition of Rac1 Promotes BMP-2-induced Osteoblastic Differentiation  Cell Death Dis  2013  4(6):e698  PubMed ID: 23807227   DOI: 10.1038/cddis.2013.226
9269  Le Thi Bang, Kanji Tsuru, Melvin Munar, Kunio Ishikawa, Radzali Othman  Mechanical behavior and cell response of PCL coated α-TCP foam for cancellous-type bone replacement  Ceramics International  2013  39:5631-5637    DOI: 10.1016/j.ceramint.2012.12.079
9270  Hsien-Te Chen, Chi-Jen Chung, Tsai-Ching Yang, Chin-Hsin Tang, Ju-Liang He  Microscopic observations of osteoblast growth on micro-arc oxidized β titanium  Applied Surface Science  2013  266:73-80    DOI: 10.1016/j.apsusc.2012.11.087
9272  Song Chen, Xuetao Shi, Shanmugavel Chinnathambi, Hongkai Wu, Nobutaka Hanagata  Generation of Microgrooved Silica Nanotube Membranes With Sustained Drug Delivery and Cell Contact Guidance Ability by Using a Teflon Microfluidic Chip  Sci Technol Adv Mater  2013  14(1):015005  PubMed ID: 27877563   DOI: 10.1088/1468-6996/14/1/015005
9273  Marco Piola, Monica Soncini, Marco Cantini, Nasser Sadr, Giulio Ferrario, Gianfranco B Fiore  Design and Functional Testing of a Multichamber Perfusion Platform for Three-Dimensional Scaffolds  ScientificWorldJournal  2013  23:123974.  PubMed ID: 24453787   DOI: 10.1155/2013/123974
9274  Kyu-Oh Kim, Byoung-Suhk Kim, Ki-Hoon Lee, Young-Hwan Park, Ick-Soo Kim  Osteoblastic Cells Culture on Electrospun Poly(ε-Caprolacton) Scaffolds Incorporating Amphiphilic PEG-POSS Telechelic  J Mater Sci Mater Med  2013  24(8):2029-36  PubMed ID: 23661256   DOI: 10.1007/s10856-013-4943-0
9275  Chunrong Yang, Yuli Li, Kaihui Nan  Biologically inspired growth of hydroxyapatite crystals on bio-organics-defined scaffolds  Materials Research Bulletin  2013  48:1128-1131    DOI: 10.1016/j.materresbull.2012.12.005
9354  Yasuhiko Abe, Yohei Okazaki, Kyou Hiasa, Keisuke Yasuda, Keisuke Nogami, Wataru Mizumachi, Isao Hirata  Bioactive Surface Modification of Hydroxyapatite  Biomed Res Int   2013  2013:626452  PubMed ID: 23862150   DOI: 10.1155/2013/626452
9277  Hiroshi Ito, Hodaka Sasaki, Kensuke Saito, Shinya Honma, Yasutomo Yajima, Masao Yoshinari  Response of Osteoblast-Like Cells to Zirconia With Different Surface Topography  Dent Mater J   2013  32(1):122-9  PubMed ID: 23370880   DOI: 10.4012/dmj.2012-208
9278  Shingen Nakamura, Hirokazu Miki, Shinsuke Kido, Ayako Nakano, Masahiro Hiasa, Asuka Oda, Hiroe Amou, Keiichiro Watanabe, Takeshi Harada, Shiro Fujii, Kyoko Takeuchi, Kumiko Kagawa, Shuji Ozaki, Toshio Matsumoto, Masahiro Abe  Activating Transcription Factor 4, an ER Stress Mediator, Is Required For, but Excessive ER Stress Suppresses Osteoblastogenesis by Bortezomib  Int J Hematol  2013  98(1):66-73  PubMed ID: 23708974   DOI: 10.1007/s12185-013-1367-z
9279  Yujiro Maeda, Hironori Hojo, Nobuyuki Shimohata, Sungjin Choi, Kenichi Yamamoto, Tsuyoshi Takato, Ung-il Chung, Shinsuke Ohba  Bone Healing by Sterilizable Calcium Phosphate Tetrapods Eluting Osteogenic Molecules  Biomaterials  2013  34(22):5530-7  PubMed ID: 23623228   DOI: 10.1016/j.biomaterials.2013.03.089
9280  Yuya Yoneyama, Tomonori Matsuno, Yoshiya Hashimoto, Tazuko Satoh  In Vitro Evaluation of H2O2 Hydrothermal Treatment of Aged Titanium Surface to Enhance Biofunctional Activity  Dent Mater J  2013  32(1):115-21  PubMed ID: 23370879   DOI: 10.4012/dmj.2012-087
9281  Akiyoshi Hoshino, Satoshi Ueha, Sanshiro Hanada, Toshio Imai, Masako Ito, Kenji Yamamoto, Kouji Matsushima, Akira Yamaguchi, Tadahiro Iimura  Roles of Chemokine Receptor CX3CR1 in Maintaining Murine Bone Homeostasis Through the Regulation of Both Osteoblasts and Osteoclasts  J Cell Sci   2013  126(Pt 4):1032-45  PubMed ID: 23264747   DOI: 10.1242/jcs.113910
9282  Hirohiko Okamura, Kaya Yoshida, Di Yang, Tatsuji Haneji  Protein Phosphatase 2A Cα Regulates Osteoblast Differentiation and the Expressions of Bone Sialoprotein and Osteocalcin via Osterix Transcription Factor  J Cell Physiol  2013  228(5):1031-7  PubMed ID: 23042641   DOI: 10.1002/jcp.24250
9283  Takanori Kawano 1, Widyasri Prananingrum, Yuichi Ishida 1, Takaharu Goto 1, Yoshihito Naito 1, Megumi Watanabe 1, Yoritoki Tomotake 1, Tetsuo Ichikawa 1  Blue-violet Laser Modification of Titania Treated Titanium: Antibacterial and Osteo-Inductive Effects  PLoS One  2013  8(12):e84327  PubMed ID: 24358355   DOI: 10.1371/journal.pone.0084327
9284  Takanori Eguchi, Ken Watanabe, Emilio Satoshi Hara, Mitsuaki Ono, Takuo Kuboki, Stuart K Calderwood  OstemiR: A Novel Panel of microRNA Biomarkers in Osteoblastic and Osteocytic Differentiation From Mesencymal Stem Cells  PLoS One  2013  8(3):e58796  PubMed ID: 23533592   DOI: 10.1371/journal.pone.0058796
9356  Chunxia Gao Qiang Gao Yadong Li Mohamed N. Rahaman Akira Teramoto Koji Abe  In vitro evaluation of electrospun gelatin‐bioactive glass hybrid scaffolds for bone regeneration  The Journal of Applied Polymer Science  2013  127:2588-2599    DOI: 10.1002/app.37946
9276  Kazuyuki Furuya, Noriko Yamamoto, Yuki Ohyabu, Teruyuki Morikyu, Hirohide Ishige, Michael Albers, Yasuhisa Endo  Mechanism of the Tissue-Specific Action of the Selective Androgen Receptor Modulator S-101479  Biol Pharm Bull   2013  36(3):442-51  PubMed ID: 23449329   DOI: 10.1248/bpb.b12-00885
9357  Yohei Hanazaki, Jyun-ichi Masumoto, Shoichi Sato, Kazuya Furusawa, Akimasa Fukui, Naoki Sasaki  Multiscale Analysis of Changes in an Anisotropic Collagen Gel Structure by Culturing Osteoblasts  ACS Appl Mater Interfaces  2013  5(13):5937-46  PubMed ID: 23806015   DOI: 10.1021/am303254e
9359  Yuriko Furuya, Atsushi Inagaki, Masud Khan, Kaoru Mori, Josef M Penninger, Midori Nakamura, Nobuyuki Udagawa, Kazuhiro Aoki, Keiichi Ohya, Kohji Uchida, Hisataka Yasuda  Stimulation of Bone Formation in Cortical Bone of Mice Treated With a Receptor Activator of Nuclear factor-κB Ligand (RANKL)-binding Peptide That Possesses Osteoclastogenesis Inhibitory Activity  J Biol Chem  2013  288(8):5562-71  PubMed ID: 23319583   DOI: 10.1074/jbc.M112.426080
9360  Tetsuo Asakura, Yu Suzuki, Aya Nagano, David Knight, Masakatsu Kamiya, Makoto Demura  Synthesis and Characterization of Water-Soluble Silk Peptides and Recombinant Silk Protein Containing Polyalanine, the Integrin Binding Site, and Two Glutamic Acids at Each Terminal Site as a Possible Candidate for Use in Bone Repair Materials  Biomacromolecules  2013  14(10):3731-41  PubMed ID: 24004453   DOI: 10.1021/bm401118m
9361  Joaquín Ródenas-Rochina 1, José Luis Gómez Ribelles, Myriam Lebourg  Comparative Study of PCL-HAp and PCL-bioglass Composite Scaffolds for Bone Tissue Engineering  J Mater Sci Mater Med  2013  24(5):1293-308  PubMed ID: 23417519   DOI: 10.1007/s10856-013-4878-5
9362  Soner Çakmak, Anıl Sera Çakmak, Menemşe Gümüşderelioğlu  RGD-bearing Peptide-Amphiphile-Hydroxyapatite Nanocomposite Bone Scaffold: An in Vitro Study  Biomed Mater  2013  8(4):045014  PubMed ID: 23860136   DOI: 10.1088/1748-6041/8/4/045014
9364  Michiyo Tsuru, Takashi Soejima, Naoto Shiba, Kimiko Kimura, Kimiaki Sato, Yoshiaki Toyama, Kensei Nagata  Proline/arginine-rich End Leucine-Rich Repeat Protein Converts Stem Cells to Ligament Tissue and Zn(II) Influences Its Nuclear Expression  Stem Cells Dev  2013  22(14):2057-70  PubMed ID: 23442027   DOI: 10.1089/scd.2012.0695
9285  Gibson S.Nyanhong, Rosario Díaz Rodríguez, Endry Nugroho Prasetyo, Cristina Caparrós, Clarisse Ribeiro, Vitor Sencadasd, Senentxu Lanceros-Mendez, Enrique Herrero Acerobe Georg M.Guebitz  Bioactive albumin functionalized polylactic acid membranes for improved biocompatibility  Reactive and Functional Polymers  2013  73:1399-1404    DOI: 10.1016/j.reactfunctpolym.2012.12.007
9286  Yosuke Shinozaki, Tsukasa Yanagi, Yuichiro Yamaguchi, Hirofumi Kido, Tadao Fukushima  Osteogenic Evaluation of DNA/Protamine Complex Paste in Rat Cranial Defects  Journal of Hard Tissue Biology  2013  22:401-408    DOI: 10.2485/jhtb.22.401
9287  Chunxia Gao, Mohamed N Rahaman, Qiang Gao, Akira Teramoto, Koji Abe  Robotic Deposition and in Vitro Characterization of 3D Gelatin-Bioactive Glass Hybrid Scaffolds for Biomedical Applications  J Biomed Mater Res A  2013  101(7):2027-37  PubMed ID: 23255226   DOI: 10.1002/jbm.a.34496
9288  Kimberly Sloan Stakleff, Fei Lin, Laura A Smith Callahan, Mary Beth Wade, Andrew Esterle, James Miller, Matthew Graham, Matthew L Becker  Resorbable, Amino Acid-Based Poly(ester Urea)s Crosslinked With Osteogenic Growth Peptide With Enhanced Mechanical Properties and Bioactivity  Acta Biomater  2013  9(2):5132-42  PubMed ID: 22975625   DOI: 10.1016/j.actbio.2012.08.035
15473  Noboru Hasegawa, Lin Mei, Miyako Mochizuki  Pycnogenol® enhances proliferation and mineralization in osteoblast-like MC3T3-E1 cells  Phytopharmacology  2013  4:569-574   
15474  Toshihiko Shiraishi, Takuya Ohara, Shin Morishita  A Method for Applying High Cyclic Strain to Focal Adhesions and Measuring the Cell Response  Biomedical and Biotechnology Engineering  2013  3B    DOI: 10.1115/imece2013-64681
17408  Ramalingam M, Young MF, Thomas V, Sun L, Chow LC, Tison CK, Chatterjee K, Miles WC, Simon CG Jr.  Nanofiber scaffold gradients for interfacial tissue engineering  J Biomater Appl  2013  27(6):695-705  PubMed ID: 22286209   DOI: 10.1177/0885328211423783
7585  Aira Matsugaki, Gento Aramoto, Takayoshi Nakano  The alignment of MC3T3-E1 osteoblasts on steps of slip traces introduced by dislocation motion  Biomaterials  2012  33・30:7327-7335  PubMed ID: 22818653   DOI: 10.1016/j.biomaterials.2012.06.022
7624  Wei K, Li Y, Mugishima H, Teramoto A, Abe K.  Fabrication of core-sheath structured fibers for model drug release and tissue engineering by emulsion electrospinning.  Biotechnol J  2012  7:677-85  PubMed ID: 22125296   DOI: 10.1002/biot.201000473
7640  Kim DY, Park YG, Quan HY, Kim SJ, Jung MS, Chung SH.  Ginsenoside Rd stimulates the differentiation and mineralization of osteoblastic MC3T3-E1 cells by activating AMP-activated protein kinase via the BMP-2 signaling pathway.  Fitoterapia  2012  83:215-22  PubMed ID: 22061660   DOI: 10.1016/j.fitote.2011.10.017
7693  Choi BH, Choi YS, Hwang DS, Cha HJ.  Facile surface functionalization with glycosaminoglycans by direct coating with mussel adhesive protein.  Tissue Eng Part C Methods  2012  18:71-9  PubMed ID: 21895565   DOI: 10.1089/ten.TEC.2011.0384
5431  Shigeo M. TANAKA  Intracellular Ca2+ Responses of 3D-Cultured Osteoblasts to Dynamic Loading  Journal of Biomechanical Science and Engineering  2012  7:318-327    DOI: 10.1299/jbse.7.318
6171  Cetin D, Kahraman AS, Gümüşderelioğlu M.  Novel pHEMA-gelatin SPHs as bone scaffolds in dynamic cultures.  J Mater Sci Mater Med  2012  23(11):2803-12  PubMed ID: 22872315   DOI: 10.1007/s10856-012-4726-z
4395  Hasebe A, Nakamura Y, Tashima H, Takahashi K, Iijima M, Yoshimoto N, Ting K, Kuroda S, Niimi T.  The C-terminal region of NELL1 mediates osteoblastic cell adhesion through integrin α3β1.  FEBS Lett  2012  586(16):2500-6  PubMed ID: 22728432   DOI: 10.1016/j.febslet.2012.06.014
6552  Takarada T, Takarada-Iemata M, Takahata Y, Yamada D, Yamamoto T, Nakamura Y, Hinoi E, Yoneda Y.  Osteoclastogenesis is negatively regulated by D-serine produced by osteoblasts.  J Cell Physiol  2012  227(10):3477-87  PubMed ID: 22252936   DOI: 10.1002/jcp.24048
5831  Masayuki Tsukasaki , Atsushi Yamada, Kentaro Yoshimura, Agasa Miyazono, Matsuo Yamamoto, Masamichi Takami, Yoichi Miyamoto, Naoko Morimura, Ryutaro Kamijo  Nephronectin Expression Is Regulated by SMAD Signaling in Osteoblast-Like MC3T3-E1 Cells  Biochem Biophys Res Commun  2012  425(2):390-2  PubMed ID: 22842459   DOI: 10.1016/j.bbrc.2012.07.106
9196  Tohru Hayakawa, Eiji Yoshida, Yoshitaka Yoshimura, Motohiro Uo, Masao Yoshinari  MC3T3-E1 Cells on Titanium Surfaces With Nanometer Smoothness and Fibronectin Immobilization  Int J Biomater  2012  2012:743465  PubMed ID: 22675359   DOI: 10.1155/2012/743465
9198  Eun Jung Kwak 1, Young Soon Lee, Eun Mi Choi  Effect of Magnolol on the Function of Osteoblastic MC3T3-E1 Cells  Mediators Inflamm  2012  2012:829650  PubMed ID: 22474400   DOI: 10.1155/2012/829650
9199  Eiji Yoshida, Yoshitaka Yoshimura, Motohiro Uo, Masao Yoshinari, Tohru Hayakawa  Influence of Nanometer Smoothness and Fibronectin Immobilization of Titanium Surface on MC3T3-E1 Cell Behavior  J Biomed Mater Res A  2012  100(6):1556-64  PubMed ID: 22447768   DOI: 10.1002/jbm.a.34084
9200  Yoshikazu Mikami, Shinnosuke Suzuki, Yumiko Ishii, Nobukazu Watanabe, Tomihisa Takahashi, Keitaro Isokawa, Masaki J Honda  The p75 Neurotrophin Receptor Regulates MC3T3-E1 Osteoblastic Differentiation  Differentiation  2012  84(5):392-9  PubMed ID: 22906707   DOI: 10.1016/j.diff.2012.07.001
9201  Chieko Shionome, Takayuki Kawato, Natsuko Tanabe, Taro Kariya, Rina Sanuki, Yuki Koyama, Naoto Suzuki, Noriyoshi Shimizu, Masao Maeno  Compressive Force Induces the Expression of Bone Remodeling-Related Proteins via Interleukin-11 Production in MC3T3-E1 Cells  Journal of Hard Tissue Biology  2012  21:65-74    DOI: 10.2485/jhtb.21.65
9202  Tomohiro Itoh, Masashi Ando, Yasuyuki Tsukamasa, Yukihiro Akao  Expression of BMP-2 and Ets1 in BMP-2-stimulated Mouse Pre-Osteoblast Differentiation Is Regulated by microRNA-370  FEBS Lett  2012  586(12):1693-701  PubMed ID: 22587915   DOI: 10.1016/j.febslet.2012.04.014
9203  CHUNRONG YANG  Enhanced physicochemical properties of collagen by using EDC/NHS-crosslinking  Bulletin of Materials Science  2012  35:913–918    DOI: 10.1007/s12034-012-0376-5
9204  Takayuki Nonoyama, Takatoshi Kinoshita, Masahiro Higuchi, Kenji Nagata, Masayoshi Tanaka, Mari Kamada, Kimiyasu Sato, Katsuya Kato  Arrangement techniques of proteins and cells using amorphous calcium phosphate nanofiber scaffolds  Applied Surface Science  2012  262:8-12    DOI: 10.1016/j.apsusc.2011.12.009
9206  A.Valanezhad, K.Tsuru, M.Maruta, G.Kawachi, S.Matsuya, K.Ishikawa  A new biocompatible coating layer applied on titanium substrates using a modified zinc phosphatizing method  Surface and Coatings Technology  2012  206:2207-2212    DOI: 10.1016/j.surfcoat.2011.09.064
9207  C. Ribeiro a, S. Moreira b, V. Correia ac, V. Sencadas ad, J.G. Rocha c, F. M. Gama b, J. L. Gómez Ribelles ef and S. Lanceros-Méndez  Enhanced proliferation of pre-osteoblastic cells by dynamic piezoelectric stimulation    2012  2:11504-11509    DOI: 10.1039/C2RA21841K
9208  Kenichi Harimoto, Yasuhiro Yoshida, Kumiko Yoshihara, Noriyuki Nagaoka, Takuya Matsumoto, Yoh-ichi Tagawa  Osteoblast Compatibility of Materials Depends on Serum Protein Absorbability in Osteogenesis  Dent Mater J  2012  31(4):674-80  PubMed ID: 22864224   DOI: 10.4012/dmj.2012-075
9209  ChunRong Yang, YingJun Wang, XiaoFeng Chen  Mineralization Regulation and Biological Influence of Bioactive Glass-Collagen-Phosphatidylserine Composite Scaffolds  Sci China Life Sci  2012  55(3):236-40  PubMed ID: 22527520   DOI: 10.1007/s11427-012-4291-1
9210  Masayuki Shimizu, Yasuhiro Kobayashi, Toshihide Mizoguchi, Hiroaki Nakamura, Ichiro Kawahara, Nobuyo Narita, Yuki Usui, Kaoru Aoki, Kazuo Hara, Hisao Haniu, Nobuhide Ogihara, Norio Ishigaki, Koichi Nakamura, Hiroyuki Kato, Masatomo Kawakubo, Yoshiko Dohi, Seiichi Taruta, Yoong Ahm Kim, Morinobu Endo, Hidehiro Ozawa, Nobuyuki Udagawa, Naoyuki Takahashi, Naoto Saito  Carbon Nanotubes Induce Bone Calcification by Bidirectional Interaction With Osteoblasts  Adv Mater  2012  24(16):2176-85  PubMed ID: 22447724   DOI: 10.1002/adma.201103832
9211  Hiroaki Watanabe, Kensuke Saito, Katsutoshi Kokubun, Hodaka Sasaki, Masao Yoshinari  Change in Surface Properties of Zirconia and Initial Attachment of Osteoblastlike Cells With Hydrophilic Treatment  Dent Mater J  2012  31(5):806-14  PubMed ID: 23037844   DOI: 10.4012/dmj.2012-069
9212  V. Sencadas, C. Ribeiro, J. Nunes-Pereira, V. Correia & S. Lanceros-Méndez   Fiber average size and distribution dependence on the electrospinning parameters of poly(vinylidene fluoride–trifluoroethylene) membranes for biomedical applications  Applied Physics A  2012  109:685–691    DOI: 10.1007/s00339-012-7101-5
9213  Kaushik Chatterjee, Stevephen Hung 2, Girish Kumar 3, Carl G Simon 4  Time-Dependent Effects of Pre-Aging 3D Polymer Scaffolds in Cell Culture Medium on Cell Proliferation  J Funct Biomater  2012  3(2):372-81  PubMed ID: 24955538   DOI: 10.3390/jfb3020372
9214  Ming-Yue Huang, Ujjial K Bhawal, Noboru Kuboyama, Wei-Jen Chang, Sheng-Yang Lee, Yoshimitsu Abiko  Effect of Reactive Oxygen on Hyaluronan Mediated Motility Receptor Expression in Osteoblasts  Journal of Hard Tissue Biology  2012  21:127-132    DOI: 10.2485/jhtb.21.127
9215  Tomohiro Itoh, Yuko Ito, Yoshinori Ohtsuki, Masashi Ando, Yasuyuki Tsukamasa, Nami Yamada, Tomoki Naoe, Yukihiro Akao  Microvesicles Released From Hormone-Refractory Prostate Cancer Cells Facilitate Mouse Pre-Osteoblast Differentiation  J Mol Histol  2012  43(5):509-15  PubMed ID: 22526510   DOI: 10.1007/s10735-012-9415-1
9216  Hong Li, Yunsheng Ge, Pengyun Zhang, Lingxiang Wu, Shiyi Chen  The Effect of Layer-By-Layer Chitosan-Hyaluronic Acid Coating on Graft-To-Bone Healing of a Poly(ethylene Terephthalate) Artificial Ligament  J Biomater Sci Polym Ed  2012  23(1-4):425-38  PubMed ID: 21255485   DOI: 10.1163/092050610X551989
9217  Hiromi Ochiai, Shoko Okada, Akiko Saito, Kazuto Hoshi, Haruto Yamashita, Tsuyoshi Takato, Toshifumi Azuma  Inhibition of Insulin-Like Growth factor-1 (IGF-1) Expression by Prolonged Transforming Growth factor-β1 (TGF-β1) Administration Suppresses Osteoblast Differentiation  J Biol Chem  2012  287(27):22654-61  PubMed ID: 22573330   DOI: 10.1074/jbc.M111.279091
9219  Aira Matsugaki, Gento Aramoto, Takuya Ishimoto, Takayoshi Nakano  Control of Osteoblastic Cell Behavior by Surface Topography Introduced by Plastic Deformation of Ti Single Crystal with h.c.p. Structure  Materials Science Forum  2012  706-709    DOI: 10.4028/
9220  ChunRong Yang, YingJun Wang & XiaoFeng Chen   Preparation and evaluation of biomimetric nano-hydroxyapatite-based composite scaffolds for bone-tissue engineering  Chinese Science Bulletin  2012  57:2787–2792    DOI: 10.1007/s11434-012-5201-4
9221  Jung-Seob Lee, Hwang Do Cha, Jin-Hyung Shim, Jin Woo Jung, Jong Young Kim, Dong-Woo Cho  Effect of Pore Architecture and Stacking Direction on Mechanical Properties of Solid Freeform Fabrication-Based Scaffold for Bone Tissue Engineering  J Biomed Mater Res A  2012  100(7):1846-53  PubMed ID: 22488723   DOI: 10.1002/jbm.a.34149
9222  Rikako Miyamoto, Asuka Ozawa, Takeshi Yamada, Hirobumi Shibata, Katsumi Yoshida, Osamu Yamanuro, Kazuaki Hashimoto  PROLIFERATION AND DIFFERENTIATION OF OSTEOBLAST-LIKE CELLS ON β-TRICALCIUM PHOSPHATE DOPED WITH MANGANESE (II) IONS  Phosphorus Research Bulletin  2012  26:87-90    DOI: 10.3363/prb.26.87
9223  Inho Han, Barbora Vagaska, Hyok Jin Seo, Jae Kyeong Kang, Byeong-Ju Kwon, Mi Hee Lee, Jong-Chul Parkb  Promoted cell and material interaction on atmospheric pressure plasma treated titanium  Applied Surface Science  2012  258:4718-4723    DOI: 10.1016/j.apsusc.2012.01.065
9224  Menemşe Gümüşderelioğlu, Anıl S. Kahraman & Ali Tuncel   Magnetic poly(glycerol dimethacrylate) latex particles: synthesis, characterization and cellular interactions  Polymer Bulletin  2012  69:323–335    DOI: 10.1007/s00289-012-0732-z
9225  Fukunaga Otsuka, Yu Kataoka, Takashi Miyazaki  Enhanced Osteoblast Response to Electrical Discharge Machining Surface  Dent Mater J  2012  31(2):309-15  PubMed ID: 22447066   DOI: 10.4012/dmj.2011-039
9226  Tadashi Honjo, Satoshi Kubota, Hiroshi Kamioka, Yasuyo Sugawara, Yoshihito Ishihara, Takashi Yamashiro, Masaharu Takigawa, Teruko Takano-Yamamoto  Promotion of Ccn2 Expression and Osteoblastic Differentiation by Actin Polymerization, Which Is Induced by Laminar Fluid Flow Stress  J Cell Commun Signal  2012  6(4):225-32  PubMed ID: 22956334   DOI: 10.1007/s12079-012-0177-z
9228  Jong Bum KIM, Toshimitsu OKUDERA, Toshitake FURUSAWA, Masaaki SATO, Weiqi YAN, Yuta MATSUSHIMA, Hidero UNUMA, Takashi SASANO  In vivo and in vitro biological efficacy of double-layer coating of titanium with gelatin and calcium phosphate  Journal of the Ceramic Society of Japan  2012  20:589-593    DOI: 10.2109/jcersj2.120.589
9229  Marco Cantini, Patricia Rico, David Moratal and Manuel Salmerón-Sánchez   Controlled wettability, same chemistry: biological activity of plasma-polymerized coatings  oft Matter  2012  8,:5575-5584    DOI: 10.1039/C2SM25413A
9230  Tingting Zhu, Bum-Soon Lim, Hee Chul Park, Kyung Mi Son, Hyeong-Cheol Yang  Effects of the Iron-Chelating Agent Deferoxamine on Triethylene Glycol Dimethacrylate, 2-hydroxylethyl Methacrylate, Hydrogen Peroxide-Induced Cytotoxicity  J Biomed Mater Res B Appl Biomater  2012  100(1):197-205  PubMed ID: 22102427   DOI: 10.1002/jbm.b.31939
9231  Kazuaki Nagayama, Yuki Kimura, Narutaka Makino, Takeo Matsumoto  Strain Waveform Dependence of Stress Fiber Reorientation in Cyclically Stretched Osteoblastic Cells: Effects of Viscoelastic Compression of Stress Fibers  Am J Physiol Cell Physiol  2012  302(10):C1469-78  PubMed ID: 22357736   DOI: 10.1152/ajpcell.00155.2011
9233  Takashi Watanabe, Yoshihiro Tamamura, Akiyoshi Hoshino, Yuji Makino, Hiroshi Kamioka, Teruo Amagasa, Akira Yamaguchi, Tadahiro Iimura  Increasing Participation of Sclerostin in Postnatal Bone Development, Revealed by Three-Dimensional Immunofluorescence Morphometry  Bone  2012  ;51(3):447-58  PubMed ID: 22766096   DOI: 10.1016/j.bone.2012.06.019
9234  Tomoyuki Koyama, Chie Nakajima, Sogo Nishimoto, Masamichi Takami, Je-Tae Woo, Kazunaga Yazawa  Suppressive Effects of the Leaf of Terminalia Catappa L. On Osteoclast Differentiation in Vitro and Bone Weight Loss in Vivo  J Nutr Sci Vitaminol (Tokyo)  2012  58(2):129-35  PubMed ID: 22790571   DOI: 10.3177/jnsv.58.129
9235  C Ribeiro, J A Panadero, V Sencadas, S Lanceros-Méndez, M N Tamaño, D Moratal, M Salmerón-Sánchez, J L Gómez Ribelles  Fibronectin Adsorption and Cell Response on Electroactive Poly(vinylidene Fluoride) Films  iomed Mater  2012  7(3):035004  PubMed ID: 22356773   DOI: 10.1088/1748-6041/7/3/035004
9236  Yang Wu, Shiyi Chen, Jia Jiang, Hong Li, K,ai Gao, Pengyun Zhang  The Effect of 58S Bioactive Glass Coating on Polyethylene Terephthalates in Graft-Bone Healing  Journal of Bionic Engineering  2012  9:470-477    DOI: 10.1016/S1672-6529(11)60133-9
9237  Kenichi Yamamoto, Hironori Hojo, Isao Koshima, Ung-il Chung, Shinsuke Ohba  Famotidine Suppresses Osteogenic Differentiation of Tendon Cells in Vitro and Pathological Calcification of Tendon in Vivo  J Orthop Res  2012  30(12):1958-62  PubMed ID: 22592911   DOI: 10.1002/jor.22146
9218  Norio Yamakawa, Kazuko Kaneda, Yusuke Saito, Emi Ichihara, Kazuhiro Morishita  The Increased Expression of Integrin α6 (ITGA6) Enhances Drug Resistance in EVI1(high) Leukemia  PLoS One  2012  7(1):e30706  PubMed ID: 22295105   DOI: 10.1371/journal.pone.0030706
9240  Hirotaka OOMINE, Megumi FUSE, Tohru HAYAKAWA, Masahiko FUKUMOTO  Fabrication of the Fibronectin-immobilized Three-Dimensional Porous Poly(lactic acid) Scaffold and Initial Mouse Osteoblast-like Cell Attachment  Journal of Oral Tissue Engineering  2012  10:59-66    DOI: 10.11223/jarde.10.59
9241  Chunxia Gao, Qiang Gao, Yadong Li, Mohamed N Rahaman, Akira Teramoto, Koji Abe  Preparation and in Vitro Characterization of Electrospun PVA Scaffolds Coated With Bioactive Glass for Bone Regeneration  J Biomed Mater Res A  2012  100(5):1324-34  PubMed ID: 22374712   DOI: 10.1002/jbm.a.34072
9242  Masahide Takedachi, Hiroyuki Oohara, Brenda J Smith, Mitsuyoshi Iyama, Mariko Kobashi, Kenichiro Maeda, Courtney L Long, Mary B Humphrey, Barbara J Stoecker, Satoru Toyosawa, Linda F Thompson, Shinya Murakami  CD73-generated Adenosine Promotes Osteoblast Differentiation  J Cell Physiol  2012  227(6):2622-31  PubMed ID: 21882189   DOI: 10.1002/jcp.23001
9243  Sang-Hyun An, Takuya Matsumoto, Hiroyuki Miyajima, Atsushi Nakahira, Kyo-Han Kim, Satoshi Imazato  Porous Zirconia/Hydroxyapatite Scaffolds for Bone Reconstruction  Dent Mater  2012  28(12):1221-31  PubMed ID: 23018082   DOI: 10.1016/
9244  Murat Simşek, Merve Capkın, Ayşe Karakeçili, Menemşe Gümüşderelioğlu  Chitosan and Polycaprolactone Membranes Patterned via Electrospinning: Effect of Underlying Chemistry and Pattern Characteristics on Epithelial/Fibroblastic Cell Behavior  J Biomed Mater Res A  2012  100(12):3332-43  PubMed ID: 22733685   DOI: 10.1002/jbm.a.34287
9247  Yoshiyuki Wada, Morimichi Mizuno, Yoshinobu Nodasaka, Masato Tamura  The Effect of Enamel Matrix Derivative on Spreading, Proliferation, and Differentiation of Osteoblasts Cultured on Zirconia  Int J Oral Maxillofac Implants  2012  27(4):849-58  PubMed ID: 22848887  
15472  Toshihiko Shiraishi, Takuya Ohara, Shin Morishita, Ryohei Takeuchi  Response of an Osteoblast to Cyclic Strain at Its Focal Adhesions Using Magnetic Micropillars  Biomedical and Biotechnology  2012  2    DOI: 10.1115/imece2012-89919
14283  Castillo JA, Borchmann DE, Cheng AY, Wang Y, Hu C, García AJ, Weck M.  Well-defined Poly(lactic acid)s Containing Poly(ethylene glycol) Side-chains  Macromolecules  2012  45(1):62-69  PubMed ID: 22279245   DOI: 10.1021/ma2016387
7586  Inaguma T, Han J, Isoda H.  Improvement of insulin resistance by Cyanidin 3-glucoside, anthocyanin from black beans through the up-regulation of GLUT4 gene expression.  BMC Proc  2011  5 Suppl 8:P21  PubMed ID: 22373152   DOI: 10.1186/1753-6561-5-S8-P21
7630  Skrtic D, Antonucci JM.  Bioactive polymeric composites for tooth mineral regeneration: physicochemical and cellular aspects.  J Funct Biomater  2011  2:271-307  PubMed ID: 22102967   DOI: 10.3390/jfb2030271
7634  Han SH, Kim KH, Han JS, Koo KT, Kim TI, Seol YJ, Lee YM, Ku Y, Rhyu IC.  Response of osteoblast-like cells cultured on zirconia to bone morphogenetic protein-2.  J Periodontal Implant Sci  2011  41:227-33  PubMed ID: 22087413   DOI: 10.5051/jpis.2011.41.5.227
7679  Takeuchi N, Machigashira M, Yamashita D, Shirakata Y, Kasuga T, Noguchi K, Ban S.  Cellular compatibility of a gamma-irradiated modified siloxane-poly(lactic acid)-calcium carbonate hybrid membrane for guided bone regeneration.  Dent Mater J  2011  30:730-8  PubMed ID: 21946495   DOI: 10.4012/dmj.2011-075
7694  Kriebitzsch C, Verlinden L, Eelen G, van Schoor NM, Swart K, Lips P, Meyer MB, Pike JW, Boonen S, Carlberg C, Vitvitsky V, Bouillon R, Banerjee R, Verstuyf A.  1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase.  J. Bone Miner. Res.  2011  26:2991-3000  PubMed ID: 21898591   DOI: 10.1002/jbmr.493
7719  Takahata Y, Takarada T, Hinoi E, Nakamura Y, Fujita H, Yoneda Y.  Osteoblastic γ-aminobutyric acid, type B receptors negatively regulate osteoblastogenesis toward disturbance of osteoclastogenesis mediated by receptor activator of nuclear factor κB ligand in mouse bone.  J. Biol. Chem.  2011  286:32906-17  PubMed ID: 21828041   DOI: 10.1074/jbc.M111.253526
7744  Yoshida K, Higuchi C, Nakura A, Yoshikawa H.  Spleen tyrosine kinase suppresses osteoblastic differentiation through MAPK and PKCα.  Biochem. Biophys. Res. Commun.  2011  411:774-9  PubMed ID: 21782794   DOI: 10.1016/j.bbrc.2011.07.023
7758  Ren G, Wang K, Chang R, Su Y, Wang J, Su J, Han B.  Simultaneous administration of fluoride and selenite regulates proliferation and apoptosis in murine osteoblast-like MC3T3-E1 cells by altering osteoprotegerin.  Biol Trace Elem Res  2011  144:1437-48  PubMed ID: 21739163   DOI: 10.1007/s12011-011-9130-x
7773  Tsukasaki M, Yamada A, Suzuki D, Aizawa R, Miyazono A, Miyamoto Y, Suzawa T, Takami M, Yoshimura K, Morimura N, Yamamoto M, Kamijo R.  Expression of POEM, a positive regulator of osteoblast differentiation, is suppressed by TNF-α.  Biochem. Biophys. Res. Commun.  2011  410:766-70  PubMed ID: 21689636   DOI: 10.1016/j.bbrc.2011.06.048
7774  Furugaki K, Moriya Y, Iwai T, Yorozu K, Yanagisawa M, Kondoh K, Fujimoto-Ohuchi K, Mori K.  Erlotinib inhibits osteolytic bone invasion of human non-small-cell lung cancer cell line NCI-H292.  Clin. Exp. Metastasis  2011  28:649-59  PubMed ID: 21688034   DOI: 10.1007/s10585-011-9398-4
7777  Okamura H, Yoshida K, Ochiai K, Haneji T.  Reduction of protein phosphatase 2A Cα enhances bone formation and osteoblast differentiation through the expression of bone-specific transcription factor Osterix.  Bone  2011  49:368-75  PubMed ID: 21683816   DOI: 10.1016/j.bone.2011.06.004
7790  Kataoka Y, Tamaki Y, Miyazaki T.  Synergistic responses of superficial chemistry and micro topography of titanium created by wire-type electric discharge machining.  Biomed Mater Eng  2011  21:113-21  PubMed ID: 21654067   DOI: 10.3233/BME-2011-0661
7792  Zhang W, Wang H, Oyane A, Tsurushima H, Chu PK.  Osteoblast differentiation and disinfection induced by nitrogen plasma-treated surfaces.  Biomed Mater Eng  2011  21:75-82  PubMed ID: 21654064   DOI: 10.3233/BME-2011-0657
7802  Tagaya M, Ikoma T, Takemura T, Hanagata N, Yoshioka T, Tanaka J.  Effect of interfacial proteins on osteoblast-like cell adhesion to hydroxyapatite nanocrystals.  Langmuir  2011  27:7645-53  PubMed ID: 21615097   DOI: 10.1021/la200621p
7812  Tagaya M, Ikoma T, Takemura T, Hanagata N, Okuda M, Yoshioka T, Tanaka J.  Detection of interfacial phenomena with osteoblast-like cell adhesion on hydroxyapatite and oxidized polystyrene by the quartz crystal microbalance with dissipation.  Langmuir  2011  27:7635-44  PubMed ID: 21595447   DOI: 10.1021/la200008z
7819  Yonezawa T, Lee JW, Hibino A, Asai M, Hojo H, Cha BY, Teruya T, Nagai K, Chung UI, Yagasaki K, Woo JT.  Harmine promotes osteoblast differentiation through bone morphogenetic protein signaling.  Biochem. Biophys. Res. Commun.  2011  409:260-5  PubMed ID: 21570953   DOI: 10.1016/j.bbrc.2011.05.001
7827  Yonezawa T, Lee JW, Akazawa H, Inagaki M, Cha BY, Nagai K, Yagasaki K, Akihisa T, Woo JT.  Osteogenic activity of diphenyl ether-type cyclic diarylheptanoids derived from Acer nikoense.  Bioorg. Med. Chem. Lett.  2011  21:3248-51  PubMed ID: 21550801   DOI: 10.1016/j.bmcl.2011.04.041
7829  Shoji K, Tsubaki M, Yamazoe Y, Satou T, Itoh T, Kidera Y, Tanimori Y, Yanae M, Matsuda H, Taga A, Nakamura H, Nishida S.  Mangiferin induces apoptosis by suppressing Bcl-xL and XIAP expressions and nuclear entry of NF-κB in HL-60 cells.  Arch. Pharm. Res.  2011  34:469-75  PubMed ID: 21547680   DOI: 10.1007/s12272-011-0316-8
7834  Hagiwara K, Goto T, Araki M, Miyazaki H, Hagiwara H.  Olive polyphenol hydroxytyrosol prevents bone loss.  Eur. J. Pharmacol.  2011  662:78-84  PubMed ID: 21539839   DOI: 10.1016/j.ejphar.2011.04.023
7837  Kang KS, Lee SJ, Lee HS, Moon W, Cho DW.  Effects of combined mechanical stimulation on the proliferation and differentiation of pre-osteoblasts.  Exp. Mol. Med.  2011  43:367-73  PubMed ID: 21532314   DOI: 10.3858/emm.2011.43.6.040
7855  Shimizu T, Tanaka T, Iso T, Matsui H, Ooyama Y, Kawai-Kowase K, Arai M, Kurabayashi M.  Notch signaling pathway enhances bone morphogenetic protein 2 (BMP2) responsiveness of Msx2 gene to induce osteogenic differentiation and mineralization of vascular smooth muscle cells.  J. Biol. Chem.  2011  286:19138-48  PubMed ID: 21471203   DOI: 10.1074/jbc.M110.175786
7870  Wei K, Li Y, Kim KO, Nakagawa Y, Kim BS, Abe K, Chen GQ, Kim IS.  Fabrication of nano-hydroxyapatite on electrospun silk fibroin nanofiber and their effects in osteoblastic behavior.  J Biomed Mater Res A  2011  97:272-80  PubMed ID: 21442728   DOI: 10.1002/jbm.a.33054
7885  Ma C, Zhang J, Fu J, Cheng L, Zhao G, Gu Y.  Up-regulation of VEGF by MC3T3-E1 cells treated with curculigoside.  Phytother Res  2011  25:922-6  PubMed ID: 21394809   DOI: 10.1002/ptr.3449
7895  Fukuno N, Matsui H, Kanda Y, Suzuki O, Matsumoto K, Sasaki K, Kobayashi T, Tamura S.  TGF-β-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts.  Biochem. Biophys. Res. Commun.  2011  408:202-7  PubMed ID: 21371434   DOI: 10.1016/j.bbrc.2011.02.127
7911  Tamaki Y, Lee WS, Kataoka Y, Miyazaki T.  A modified porous titanium sheet prepared by plasma-activated sintering for biomedical applications.  J Tissue Eng  2011  2010:425402  PubMed ID: 21350650   DOI: 10.4061/2010/425402
7916  Ogata N, Shinoda Y, Wettschureck N, Offermanns S, Takeda S, Nakamura K, Segre GV, Chung UI, Kawaguchi H.  G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone.  J. Biol. Chem.  2011  286:13733-40  PubMed ID: 21345793   DOI: 10.1074/jbc.M110.200196
7926  Okada E, Yamanaka M, Ishikawa O.  New insights into the mechanism of abnormal calcification in nephrogenic systemic fibrosis - gadolinium promotes calcium deposition of mesenchymal stem cells and dermal fibroblasts.  J. Dermatol. Sci.  2011  62:58-63  PubMed ID: 21334857   DOI: 10.1016/j.jdermsci.2011.01.009
7947  Uno K, Takarada T, Nakamura Y, Fujita H, Hinoi E, Yoneda Y.  A negative correlation between expression profiles of runt-related transcription factor-2 and cystine/glutamate antiporter xCT subunit in ovariectomized mouse bone.  J. Pharmacol. Sci.  2011  115:309-19  PubMed ID: 21325781   DOI: 10.1254/jphs.10310fp
7950  Miura K, Yamada N, Hanada S, Jung TK, Itoi E.  The bone tissue compatibility of a new Ti-Nb-Sn alloy with a low Young's modulus.  Acta Biomater  2011  7:2320-6  PubMed ID: 21316491   DOI: 10.1016/j.actbio.2011.02.008
7952  Kihara T, Ichikawa S, Yonezawa T, Lee JW, Akihisa T, Woo JT, Michi Y, Amagasa T, Yamaguchi A.  Acerogenin A, a natural compound isolated from Acer nikoense Maxim, stimulates osteoblast differentiation through bone morphogenetic protein action.  Biochem. Biophys. Res. Commun.  2011  406:211-7  PubMed ID: 21303661   DOI: 10.1016/j.bbrc.2011.02.017
7954  Uno K, Takarada T, Takarada-Iemata M, Nakamura Y, Fujita H, Hinoi E, Yoneda Y.  Negative regulation of osteoblastogenesis through downregulation of runt-related transcription factor-2 in osteoblastic MC3T3-E1 cells with stable overexpression of the cystine/glutamate antiporter xCT subunit.  J. Cell. Physiol.  2011  226:2953-64  PubMed ID: 21302293   DOI: 10.1002/jcp.22642
7969  Mikami Y, Senoo M, Lee M, Yamada K, Ochiai K, Honda MJ, Watanabe E, Watanabe N, Somei M, Takagi M.  Inhibitory effects of a tryptamine derivative on ultraviolet radiation-induced apoptosis in MC3T3-E1 mouse osteoblasts.  J. Pharmacol. Sci.  2011  115:214-20  PubMed ID: 21282935   DOI: 10.1254/jphs.10208fp
7996  Kim BY, Yoon HY, Yun SI, Woo ER, Song NK, Kim HG, Jeong SY, Chung YS.  In vitro and in vivo inhibition of glucocorticoid-induced osteoporosis by the hexane extract of Poncirus trifoliata.  Phytother Res  2011  25:1000-10  PubMed ID: 21225901   DOI: 10.1002/ptr.3373
8017  Lin J, Fan YJ, Mehl C, Zhu JJ, Chen H, Jin LY, Xu JH, Wang HM.  Eucommia ulmoides Oliv. antagonizes H2O2-induced rat osteoblastic MC3T3-E1 apoptosis by inhibiting expressions of caspases 3, 6, 7, and 9.  J Zhejiang Univ Sci B  2011  12:47-54  PubMed ID: 21194186   DOI: 10.1631/jzus.B1000057
8029  Chatterjee K, Young MF, Simon CG Jr.  Fabricating gradient hydrogel scaffolds for 3D cell culture.  Comb. Chem. High Throughput Screen.  2011  14:227-36  PubMed ID: 21143178   DOI: 10.2174/138620711795222455
8054  Chatterjee K, Sun L, Chow LC, Young MF, Simon CG Jr.  Combinatorial screening of osteoblast response to 3D calcium phosphate/poly(ε-caprolactone) scaffolds using gradients and arrays.  Biomaterials  2011  32:1361-9  PubMed ID: 21074846   DOI: 10.1016/j.biomaterials.2010.10.043
8064  Lam WM, Pan HB, Fong MK, Cheung WS, Wong KL, Li ZY, Luk KD, Chan WK, Wong CT, Yang C, Lu WW.  In Vitro characterization of low modulus linoleic acid coated strontium-substituted hydroxyapatite containing PMMA bone cement.  J. Biomed. Mater. Res. Part B Appl. Biomater.  2011  96:76-83  PubMed ID: 21053263   DOI: 10.1002/jbm.b.31741
8098  Zhang F, Tanaka H, Kawato T, Kitami S, Nakai K, Motohashi M, Suzuki N, Wang CL, Ochiai K, Isokawa K, Maeno M.  Interleukin-17A induces cathepsin K and MMP-9 expression in osteoclasts via celecoxib-blocked prostaglandin E2 in osteoblasts.  Biochimie  2011  93:296-305  PubMed ID: 20937352   DOI: 10.1016/j.biochi.2010.10.001
8101  Lee JW, Kang KS, Lee SH, Kim JY, Lee BK, Cho DW.  Bone regeneration using a microstereolithography-produced customized poly(propylene fumarate)/diethyl fumarate photopolymer 3D scaffold incorporating BMP-2 loaded PLGA microspheres.  Biomaterials  2011  32:744-52  PubMed ID: 20933279   DOI: 10.1016/j.biomaterials.2010.09.035
8121  Hanagata N, Li X, Morita H, Takemura T, Li J, Minowa T.  Characterization of the osteoblast-specific transmembrane protein IFITM5 and analysis of IFITM5-deficient mice.  J. Bone Miner. Metab.  2011  29:279-90  PubMed ID: 20838829   DOI: 10.1007/s00774-010-0221-0
8203  Cetin D, Kahraman AS, Gumu?derelio?lu M.  Novel scaffolds based on poly(2-hydroxyethyl methacrylate) superporous hydrogels for bone tissue engineering.  J Biomater Sci Polym Ed  2011  22:1157-78  PubMed ID: 20615330   DOI: 10.1163/092050610X501704
8306  Nagata M, Lonnerdal B.  Role of zinc in cellular zinc trafficking and mineralization in a murine osteoblast-like cell line.  J. Nutr. Biochem.  2011  22:172-8  PubMed ID: 20378322   DOI: 10.1016/j.jnutbio.2010.01.003
5524  Yoshimi Tsuruma, Hiroe Maruyama, Yoko Araki  Effect of a Glycoprotein (Apisin) in Royal Jelly on Proliferation and Differentiation in Skin Fibroblast and Osteoblastic Cells  Nippon Shokuhin Kagaku Kogaku Kaishi  2011  58:121-126    DOI: 10.3136/nskkk.58.121
6307  Igarashi M, Sakamoto K, Nagaoka I.  Effect of glucosamine, a therapeutic agent for osteoarthritis, on osteoblastic cell differentiation.  Int J Mol Med  2011  28(3):373-9  PubMed ID: 21537831   DOI: 10.3892/ijmm.2011.686
7957  RETNO WIDYOWATI  Alkaline phosphatase activity of Graptophyllum pictum and Sphilanthes acmella fractions against MC3T3-E1 cells as marker of osteoblast differentiation cells  Int J Pharm Pharm Sci  2011  3:34­37   
7964  Masafumi Sakonoa, Shigenori Akiyama, Tamotsu Zakoa, Shujiro Sakaki, Tomonori Waku, Naoki Tanaka, Mizuo Maeda   Application of two morphologically different fibrillar and filamentous insulin amyloids as a biomaterial for cell culture surfaces  Reactive and Functional Polymers  2011  71:324-328    DOI: 10.1016/j.reactfunctpolym.2010.10.012
8018  Menemşe Gümüşderelioğlu, Ayşe Karakeçili, T Tolga Demirtaş  Osteogenic activities of MC3T3-E1 cells on heparin-immobilized poly (caprolactone) membranes  Journal of Bioactive and Compatible Polymers  2011  26:257-269    DOI: 10.1177/0883911511406329
8142  Hong Li, Yang Wu, Yunsheng Ge, Jia Jiang, Kai Gao, Pengyun Zhang, Lingxiang Wu, Shiy iChen  Composite coating of 58S bioglass and hydroxyapatite on a poly (ethylene terepthalate) artificial ligament graft for the graft osseointegration in a bone tunnel  Applied Surface Science  2011  257:9371-9376    DOI: 10.1016/j.apsusc.2011.05.110
8213  Antonucci JM, Davis CH, Sun J, O'Donnell JN, Skrtic D.  Leachability and Cytotoxicity of an Experimental Polymeric ACP Composite.  PMSE Preprints  2011  104:300-302  PubMed ID: 26457070  
8254  Piyanuch Sommani, Hiroshi Tsuji, Hiroko Sato, Yasuhito Gotoh, Gikan H. Takaoka  Osteoblast Patterning on Silicone Rubber by using Mesenchymal Stem Cells and Carbon Negative-Ion Implantation  Transactions of the Materials Research Society of Japan  2011  36:317-320    DOI: 10.14723/tmrsj.36.317
8298  Chen X, Meng Y, Wang Y, Du C, Yang C.  A Biomimetic Material with a High Bio-responsibility for Bone Reconstruction and Tissue Engineering.  J Biomater Sci Polym Ed  2011  22(1-3):153-63  PubMed ID: 20546681   DOI: 10.1163/092050609X12583524936191
8299  Keita Ishiwata, Katsuaki Imamiya, Tetsuya Mizukami, Yoshimitsu Abiko  Reduction of BIRC6 Gene expression by reactive oxygen stress in osteoblasts  International Journal of Oral-Medical Sciences  2011  10:67-71    DOI: 10.5466/ijoms.10.67
8302  T.C. Gamboa-Martínez, J.L. Gómez Ribelles, G. Gallego Ferrer  Fibrin coating on poly (L-lactide) scaffolds for tissue engineering    2011  26:464-477    DOI: 10.1177/0883911511419834
8313  Jung Hwal Shin, Jin Woo Lee, Jin Hwa Jung, Dong-Woo Cho & Geunbae Lim  Evaluation of cell proliferation and differentiation on a poly(propylene fumarate) 3D scaffold treated with functional peptides  Journal of Materials Science  2011  46:5282–5287    DOI: 10.1007/s10853-011-5467-y
8317  Kiyoto Takemoto, Kenichi Matsuzaka, Masaki Shimono, Masao Yoshinari, Takashi Inoue  The effect of different surface roughnesses on the differentiation of MC3T3-E1 mouse osteoblasts in vitro  Oral Medicine & Pathology  2011  15:45-51    DOI: 10.3353/omp.15.45
8327  Yuan Li, Xu Xu Bao, Naoki Matsuda, Ju Ming Yao, Akira Teramoto, Koji Abe & Frank K. Ko   Investigation of osteoblast-like MC3T3-E1 cells on a novel recombinant collagen-like protein surface with triple helix structure  Journal of Materials Science  2011  46:1396–1404    DOI: 10.1007/s10853-010-4933-2
8342  Choi EM.  Honokiol isolated from Magnolia officinalis stimulates osteoblast function and inhibits the release of bone-resorbing mediators.  Int Immunopharmacol  2011  11(10):1541-5  PubMed ID: 21621646   DOI: 10.1016/j.intimp.2011.05.011
8358  Zhang W, Tsurushima H, Oyane A, Yazaki Y, Sogo Y, Ito A, Matsumura A.  BMP-2 gene-fibronectin-apatite composite layer enhances bone formation.  J Biomed Sci  2011  18:62  PubMed ID: 21859498   DOI: 10.1186/1423-0127-18-62
8360  Jung Kyu Park Jin‐Hyung Shim Kyung Shin Kang Junseok Yeom Ho Sang Jung Jong Young Kim Keum Hong Lee Tae‐Ho Kim Shin‐Yoon Kim Dong‐Woo Cho Sei Kwang Hah  Solid Free‐Form Fabrication of Tissue‐Engineering Scaffolds with a Poly(lactic‐co‐glycolic acid) Grafted Hyaluronic Acid Conjugate Encapsulating an Intact Bone Morphogenetic Protein–2/Poly(ethylene glycol) Complex  Advanced Functional Materials  2011  221:2906-2912    DOI: 10.1002/adfm.201100612
8366  Ji-Hye Lee, Yu-Bin Lee, Nae-Gyune Rim, Sun-Young Jo, Youn-Mook Lim & Heungsoo Shin  Development and characterization of nanofibrous poly(lactic-co-glycolic acid)/biphasic calcium phosphate composite scaffolds for enhanced osteogenic  Macromolecular Research  2011  19:172–179   
8374  José Antonio Gómez-Tejedor, Niek Van Overberghe, Patricia Ricoa José Luís GómezRibelles  Assessment of the parameters influencing the fiber characteristics of electrospun poly (ethyl methacrylate) membranes  European Polymer Journal   2011  47:119-129   
8380  José Ballester-Beltrán, Patricia Rico, David Moratal, Wenlong Song, João F. Mano and Manuel Salmerón-Sánchez  Role of superhydrophobicity in the biological activity of fibronectin at the cell–material interface  Soft Matter  2011  7:10803-10811    DOI: 10.1039/C1SM06102J
8389  Mikami, Yoshikazu; Somei, Masanori; Watanabe, Eri; Watanabe, Nobukazu; Takahashi, Tomihisa; J. Honda, Masaki  A Novel Bromomelatonin Derivative Suppresses Apoptosis with Regulating the Expression of Bcl-2 Family Genes  Letters in Drug Design & Discovery  2011  8:951-956    DOI: 10.2174/157018011797655287
8391  Toru Orita, Masahiro Tomita, Katsuya Kato  Regulation of Cellular Responses to Macroporous Inorganic Films Prepared by the Inverse-Opal Method  Colloids Surf B Biointerfaces  2011  84:187-97  PubMed ID: 21273052   DOI: 10.1016/j.colsurfb.2010.12.032
8417  Inho Han, Barbora Vagaska, Bong Joo Park, Mi Hee Lee, Seung Jin Lee, and Jong-Chul Park  Selective fibronectin adsorption against albumin and enhanced stem cell attachment on helium atmospheric pressure glow discharge treated titanium  Journal of Applied Physics  2011  109:124701    DOI: 10.1063/1.3599885
8420  Yan Xiang, Yuanliang Wang, Yanfeng Luo, Bingbing Zhang, Juan Xin, Danfang Zheng  Molecular Biocompatibility Evaluation of poly(D,L-lactic Acid)-Modified Biomaterials Based on Long Serial Analysis of Gene Expression  Colloids Surf B Biointerfaces  2011  85 (2):248-61  PubMed ID: 21435849   DOI: 10.1016/j.colsurfb.2011.02.036
8433  Carl G Simon Jr , Yanyin Yang, Shauna M Dorsey, Murugan Ramalingam, Kaushik Chatterjee  3D Polymer Scaffold Arrays  Methods Mol Biol  2011  671:161-74  PubMed ID: 20967629   DOI: 10.1007/978-1-59745-551-0_9
8434  J M Antonucci, D Skrtic  PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES OF REMINERALIZING, POLYMERIC ACP COMPOSITES  Polymer Prepr  2011  52(2):183-184  PubMed ID: 26456981  
8437  Virginia Llopis-Hernández, Patricia Rico, José Ballester-Beltrán, David Moratal, Manuel Salmerón-Sánchez  Role of Surface Chemistry in Protein Remodeling at the Cell-Material Interface  PLoS One  2011  6(5):e19610  PubMed ID: 21573010   DOI: 10.1371/journal.pone.0019610
8440  Xu Xu Bao, Akira Teramoto, Koji Abe  Carboxymethyl Chitosan Nonwoven Scaffold for Bone Regeneration  Key Engineering Materials  2011  464:712-716    DOI: 10.4028/
8443  Kai Wei, Byoung-Suhk Kim, Ick-Soo Kim  Fabrication and Biocompatibility of Electrospun Silk Biocomposites  Membranes (Basel)   2011  1(4):275-98  PubMed ID: 24957869   DOI: 10.3390/membranes1040275
8468  Kyu-Oh Kim, Yaeko Akada, Wei Kai, Byoung-Suhk Kim, Ick-Soo Kim  Cells Attachment Property of PVA Hydrogel Nanofibers Incorporating Hyaluronic Acid for Tissue Engineering  Journal of Biomaterials and Nanobiotechnology  2011  2:353-360    DOI: 10.4236/jbnb.2011.24044
8469  Kyung-Mi Chang, Eun-Mi Choi & Gun-Hee Kim  Effect of selected aromatic medicinal plant sancho (Zanthoxylum schinifolium) on osteoblastic MC3T3-E1 cells  Food Science and Biotechnology  2011  20:1441    DOI: 10.1007/s10068-011-0198-z
8494  Ryota Nomura, Kazuhiko Nakano, Katriina Mäkelä, Martti Vaara, Eeva Salo, Satu Alaluusua, Takashi Ooshima  Isolation and Characterization of Streptococcus Mitis From Blood of Child With Osteomyelitis  Int J Paediatr Dent  2011  21(3):192-9  PubMed ID: 21199004   DOI: 10.1111/j.1365-263X.2010.01110.x
8510  Do Yeon Kim, Mi Song Jung, Young Guk Park, Hai Dan Yuan, Hai Yan Quan, Sung Hyun Chung  Ginsenoside Rh2(S) Induces the Differentiation and Mineralization of Osteoblastic MC3T3-E1 Cells Through Activation of PKD and p38 MAPK Pathways  BMB Rep  2011  44 (10): 659-64  PubMed ID: 22026999   DOI: 10.5483/BMBRep.2011.44.10.659
8525  Do Yeon Kim, Ki Ho Park, Mi Song Jung, Bo Huang, Hai-Dan Yuan, Hai-Yan Quan, Sung Hyun Chung  Ginsenoside Rh2(S) Induces Differentiation and Mineralization of MC3T3-E1 Cells Through Activation of the PKD/AMPK Signaling Pathways  Int J Mol Med  2011  28(5):753-9  PubMed ID: 21769419   DOI: 10.3892/ijmm.2011.750
8567  Menemşe Gümüşderelioğlu, Sezin Aday  Heparin-functionalized Chitosan Scaffolds for Bone Tissue Engineering  Carbohydr Res  2011  346: 606-13  PubMed ID: 21333274   DOI: 10.1016/j.carres.2010.12.007
9205  Subhadip Bodhak, Masanori Kikuchi, Ayako Oyane, Yu Sogo, Hideo Tsurushima, Atsuo Ito  Influence of Ca2+ and Mg2+ Supplementation on In Vitro Biological Properties of Hydroxyapatite/Collagen Nanocomposite Membrane  Key Engineering Materials  2011  493-494:126-131    DOI: 10.4028/
15467  Ok Hee Jeon, Yeong-Min Yoo, Kyung Hwan Kim, Christopher R. Jacobs, Chi Hyun Kim  Primary Cilia-Mediated Osteogenic Response to Fluid Flow Occurs via Increases in Focal Adhesion and Akt Signaling Pathway in MC3T3-E1 Osteoblastic Cells  Cellular and Molecular Bioengineering  2011  4:379-388    DOI: 10.1007/s12195-011-0191-x
15468  Toshihiko Shiraishi, Kazutaka Ohashi, Shin Morishita, Ryohei Takeuchi  Investigation of Mechanism of Proliferation Promotion of Cultured Osteoblasts by Mechanical Vibration  Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology  2011  2:    DOI: 10.1115/imece2011-64845
15469  Asakura T, Nishi H, Nagano A, Yoshida A, Nakazawa Y, Kamiya M, Demura M.  NMR analysis of the fibronectin cell-adhesive sequence, Arg-Gly-Asp, in a recombinant silk-like protein and a model peptide  Biomacromolecules  2011  12(11):3910-6  PubMed ID: 21955288   DOI: 10.1021/bm2011196
15470  Toshihiko Shiraishi, Kazuhiro Sakata, Shin Morishita, Ryohei Takeuchi  Investigation of a Cell Mechanosensing System by Measuring Cytoskeletal Deformation and Intracellular Calcium Ion Concentration  Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology  2011  2    DOI: 10.1115/imece2011-64843
15471  Akinori Sakai, Toshitaka Nakamura  Osteoblast Development in Bone Loss Due to Skeletal Unloading  Mechanosensing Biology  2011  167-178    DOI: 10.1007/978-4-431-89757-6_12
8072  Lee JW, Ahn G, Kim JY, Cho DW.  Evaluating cell proliferation based on internal pore size and 3D scaffold architecture fabricated using solid freeform fabrication technology.  J Mater Sci Mater Med  2010  21:3195-205  PubMed ID: 20981473   DOI: 10.1007/s10856-010-4173-7
8082  Sun J, Ding Y, Lin NJ, Zhou J, Ro H, Soles CL, Cicerone MT, Lin-Gibson S.  Exploring cellular contact guidance using gradient nanogratings.  Biomacromolecules  2010  11:3067-72  PubMed ID: 20954734   DOI: 10.1021/bm100883m
8099  Bae J, Goto S, Mie M, Kobatake E.  Construction of a thermostable cell adhesion protein for reverse transfection.  J. Biotechnol.  2010  150:447-51  PubMed ID: 20934468   DOI: 10.1016/j.jbiotec.2010.09.960
8105  Ahn G, Park JH, Kang T, Lee JW, Kang HW, Cho DW.  Effect of pore architecture on oxygen diffusion in 3D scaffolds for tissue engineering.  J Biomech Eng  2010  132:104506  PubMed ID: 20887024   DOI: 10.1115/1.4002429
8122  Choi BH, Choi YS, Kang DG, Kim BJ, Song YH, Cha HJ.  Cell behavior on extracellular matrix mimic materials based on mussel adhesive protein fused with functional peptides.  Biomaterials  2010  31:8980-8  PubMed ID: 20832110   DOI: 10.1016/j.biomaterials.2010.08.027
8138  Rincon C, Chen CC, Meredith JC.  Effect of poly(3-octylthiophene) doping on the attachment and proliferation of osteoblasts.  Macromol Biosci  2010  10:1536-43  PubMed ID: 20803603   DOI: 10.1002/mabi.201000172
8146  Fukushima T, Ohno J, Hayakawa T, Imayoshi R, Kawaguchi M, Doi Y, Kanaya K, Mitarai M.  Polycationic protamine for water-insoluble complex formation with DNA.  Dent Mater J  2010  29:529-35  PubMed ID: 20733264   DOI: 10.4012/dmj.2009-131
8154  Sumitomo A, Ishino R, Urahama N, Inoue K, Yonezawa K, Hasegawa N, Horie O, Matsuoka H, Kondo T, Roeder RG, Ito M.  The transcriptional mediator subunit MED1/TRAP220 in stromal cells is involved in hematopoietic stem/progenitor cell support through osteopontin expression.  Mol. Cell. Biol.  2010  30:4818-27  PubMed ID: 20713445   DOI: 10.1128/MCB.01348-09
8165  Ding Y, Liang C, Yang SY, Ra JC, Choi EM, Kim JA, Kim YH.  Phenolic compounds from Artemisia iwayomogi and their effects on osteoblastic MC3T3-E1 cells.  Biol. Pharm. Bull.  2010  33:1448-53  PubMed ID: 20686247   DOI: 10.1248/bpb.33.1448
8173  Fujimoto K, Kiyosaki T, Mitsui N, Mayahara K, Omasa S, Suzuki N, Shimizu N.  Low-intensity laser irradiation stimulates mineralization via increased BMPs in MC3T3-E1 cells.  Lasers Surg Med  2010  42:519-26  PubMed ID: 20662028   DOI: 10.1002/lsm.20880
8178  Kiyosaki T, Mitsui N, Suzuki N, Shimizu N.  Low-level laser therapy stimulates mineralization via increased Runx2 expression and ERK phosphorylation in osteoblasts.  Photomed Laser Surg  2010  28 Suppl 1:S167-72  PubMed ID: 20649430   DOI: 10.1089/pho.2009.2693
8192  Zhang F, Koyama Y, Sanuki R, Mitsui N, Suzuki N, Kimura A, Nakajima A, Shimizu N, Maeno M.  IL-17A stimulates the expression of inflammatory cytokines via celecoxib-blocked prostaglandin in MC3T3-E1 cells.  Arch. Oral Biol.  2010  55:679-88  PubMed ID: 20630498   DOI: 10.1016/j.archoralbio.2010.06.003
8219  Itoh T, Takeda S, Akao Y.  MicroRNA-208 modulates BMP-2-stimulated mouse preosteoblast differentiation by directly targeting V-ets erythroblastosis virus E26 oncogene homolog 1.  J. Biol. Chem.  2010  285:27745-52  PubMed ID: 20576608   DOI: 10.1074/jbc.M110.105080
8225  Dhawan P, Christakos S.  Novel regulation of 25-hydroxyvitamin D3 24-hydroxylase (24(OH)ase) transcription by glucocorticoids: cooperative effects of the glucocorticoid receptor, C/EBP beta, and the Vitamin D receptor in 24(OH)ase transcription.  J. Cell. Biochem.  2010  110:1314-23  PubMed ID: 20564225   DOI: 10.1002/jcb.22645
8230  Yotsumoto N, Takeoka M, Yokoyama M.  Tail-suspended mice lacking calponin H1 experience decreased bone loss.  Tohoku J. Exp. Med.  2010  221:221-7  PubMed ID: 20551601   DOI: 10.1620/tjem.221.221
8247  Zhang F, Wang CL, Koyama Y, Mitsui N, Shionome C, Sanuki R, Suzuki N, Mayahara K, Shimizu N, Maeno M.  Compressive force stimulates the gene expression of IL-17s and their receptors in MC3T3-E1 cells.  Connect. Tissue Res.  2010  51:359-69  PubMed ID: 20497006   DOI: 10.3109/03008200903456942
8248  Kishimoto K, Kato A, Osada S, Nishizuka M, Imagawa M.  Fad104, a positive regulator of adipogenesis, negatively regulates osteoblast differentiation.  Biochem. Biophys. Res. Commun.  2010  397:187-91  PubMed ID: 20493170   DOI: 10.1016/j.bbrc.2010.05.077
8285  Rico P, Gonzalez-Garcia C, Petrie TA, Garcia AJ, Salmeron-Sanchez M.  Molecular assembly and biological activity of a recombinant fragment of fibronectin (FNIII(7-10)) on poly(ethyl acrylate).  Colloids Surf B Biointerfaces  2010  78:310-6  PubMed ID: 20409696   DOI: 10.1016/j.colsurfb.2010.03.019
8288  Takeda K, Takahashi NH, Yoshizawa M, Shibahara S.  Lipocalin-type prostaglandin D synthase as a regulator of the retinoic acid signalling in melanocytes.  J. Biochem.  2010  148:139-48  PubMed ID: 20403807   DOI: 10.1093/jb/mvq040
8291  Hirai T, Kaneshige K, Kurosaki T, Nishio H.  Functional expression of 5-HT2A receptor in osteoblastic MC3T3-E1 cells.  Biochem. Biophys. Res. Commun.  2010  396:278-82  PubMed ID: 20399747   DOI: 10.1016/j.bbrc.2010.04.078
8304  Nakajima K, Komiyama Y, Hojo H, Ohba S, Yano F, Nishikawa N, Ihara S, Aburatani H, Takato T, Chung UI.  Enhancement of bone formation ex vivo and in vivo by a helioxanthin-derivative.  Biochem. Biophys. Res. Commun.  2010  395:502-8  PubMed ID: 20382113   DOI: 10.1016/j.bbrc.2010.04.041
8310  Arano T, Sato T, Matsuzaka K, Ikada Y, Yoshinari M.  Osteoblastic cell proliferation with uniform distribution in a large scaffold using radial-flow bioreactor.  Tissue Eng Part C Methods  2010  16:1387-98  PubMed ID: 20367244   DOI: 10.1089/ten.TEC.2009.0377
8324  Kim BJ, Choi YS, Choi BH, Lim S, Song YH, Cha HJ.  Mussel adhesive protein fused with cell adhesion recognition motif triggers integrin-mediated adhesion and signaling for enhanced cell spreading, proliferation, and survival.  J Biomed Mater Res A  2010  94:886-92  PubMed ID: 20336754   DOI: 10.1002/jbm.a.32768
8329  Usui Y, Uematsu T, Uchihashi T, Takahashi M, Takahashi M, Ishizuka M, Doto R, Tanaka H, Komazaki Y, Osawa M, Yamada K, Yamaoka M, Furusawa K.  Inorganic polyphosphate induces osteoblastic differentiation.  J. Dent. Res.  2010  89:504-9  PubMed ID: 20332330   DOI: 10.1177/0022034510363096
8344  Oya K, Tanaka Y, Moriyama Y, Yoshioka Y, Kimura T, Tsutsumi Y, Doi H, Nomura N, Noda K, Kishida A, Hanawa T.  Differences in the bone differentiation properties of MC3T3-E1 cells on polished bulk and sputter-deposited titanium specimens.  J Biomed Mater Res A  2010  94:611-8  PubMed ID: 20198694   DOI: 10.1002/jbm.a.32751
8348  Gonzalez-Garcia C, Sousa SR, Moratal D, Rico P, Salmeron-Sanchez M.  Effect of nanoscale topography on fibronectin adsorption, focal adhesion size and matrix organisation.  Colloids Surf B Biointerfaces  2010  77:181-90  PubMed ID: 20185279   DOI: 10.1016/j.colsurfb.2010.01.021
8370  Fernandes H, Dechering K, van Someren E, Steeghs I, Apotheker M, Mentink A, van Blitterswijk C, de Boer J.  Effect of chordin-like 1 on MC3T3-E1 and human mesenchymal stem cells.  Cells Tissues Organs (Print)  2010  191:443-52  PubMed ID: 20130390   DOI: 10.1159/000281825
8376  Yasuda Y, Tatematsu Y, Fujii S, Maeda H, Akamine A, Torabinejad M, Saito T.  Effect of MTAD on the differentiation of osteoblast-like cells.  J Endod  2010  36:260-3  PubMed ID: 20113785   DOI: 10.1016/j.joen.2009.11.002
8403  Kyung-Mi Chang, Eun-Mi Choi and Gun-Hee Kim  Chemical constituents of Chrysanthemum indicum L. flower oil and effect on osteoblastic MC3T3-E1 cells  Food Science and Biotechnology  2010  19:815-819    DOI: 10.1007/s10068-010-0114-y
8404  Yan Ding, Chun Liang, Huu Tung Nguyen, Eun Mi Choi, Jeong Ah Kim, and Young Ho Kim  Chemical Constituents from Acer mandshuricum and Their Effects on the Function of Osteoblastic MC3T3-E1 Cells  Bull. Korean Chem. Soc.  2010  31:929-933    DOI: 10.5012/bkcs.2010.31.04.929
8421  Rincon C, Meredith JC.  Osteoblast adhesion and proliferation on poly(3-octylthiophene) thin films.  Macromol Biosci  2010  10:258-64  PubMed ID: 20014196   DOI: 10.1002/mabi.200900243
8422  Sanuki R, Shionome C, Kuwabara A, Mitsui N, Koyama Y, Suzuki N, Zhang F, Shimizu N, Maeno M.  Compressive force induces osteoclast differentiation via prostaglandin E(2) production in MC3T3-E1 cells.  Connect. Tissue Res.  2010  51:150-8  PubMed ID: 20001844   DOI: 10.3109/03008200903168484
8428  Tseng W, Lu J, Bishop GA, Watson AD, Sage AP, Demer L, Tintut Y.  Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids.  J. Lipid Res.  2010  51:1010-6  PubMed ID: 19965598   DOI: 10.1194/jlr.M001099
8448  Moore NM, Lin NJ, Gallant ND, Becker ML.  The use of immobilized osteogenic growth peptide on gradient substrates synthesized via click chemistry to enhance MC3T3-E1 osteoblast proliferation.  Biomaterials  2010  31:1604-11  PubMed ID: 19932505   DOI: 10.1016/j.biomaterials.2009.11.011
8459  Obara M, Sakuma T, Fujikawa K.  The third type III module of human fibronectin mediates cell adhesion and migration.  J. Biochem.  2010  147:327-35  PubMed ID: 19880379   DOI: 10.1093/jb/mvp168
8473  Akman AC, Seda Ti?li R, Gumu?derelio?lu M, Nohutcu RM.  Bone morphogenetic protein-6-loaded chitosan scaffolds enhance the osteoblastic characteristics of MC3T3-E1 cells.  Artif Organs  2010  34:65-74  PubMed ID: 19821811   DOI: 10.1111/j.1525-1594.2009.00798.x
8481  Watanabe-Takano H, Takano K, Keduka E, Endo T.  M-Ras is activated by bone morphogenetic protein-2 and participates in osteoblastic determination, differentiation, and transdifferentiation.  Exp. Cell Res.  2010  316:477-90  PubMed ID: 19800879   DOI: 10.1016/j.yexcr.2009.09.028
8506  Hong Z, Mello A, Yoshida T, Luan L, Stern PH, Rossi A, Ellis DE, Ketterson JB.  Osteoblast proliferation on hydroxyapatite coated substrates prepared by right angle magnetron sputtering.  J Biomed Mater Res A  2010  93:878-85  PubMed ID: 19705463   DOI: 10.1002/jbm.a.32556
8633  Nakamura M, Nagai A, Tanaka Y, Sekijima Y, Yamashita K.  Polarized hydroxyapatite promotes spread and motility of osteoblastic cells.  J Biomed Mater Res A  2010  92:783-90  PubMed ID: 19274714   DOI: 10.1002/jbm.a.32404
6121  Nakamura S, Matsumoto T, Sasaki J, Egusa H, Lee KY, Nakano T, Sohmura T, Nakahira A.  Effect of calcium ion concentrations on osteogenic differentiation and hematopoietic stem cell niche-related protein expression in osteoblasts.  Tissue Eng Part A  2010  16(8):2467-73  PubMed ID: 20214455   DOI: 10.1089/ten.TEA.2009.0337
4738  Yuji Hatakeyama , Junko Hatakeyama , Yuriko Maruya, Kyoko Oka, Eichi Tsuruga, Tetsuichiro Inai and Yoshihiko Sawa  Growth Differentiation Factor 5 (GDF-5) Induces Matrix Metalloproteinase 2 (MMP-2) Expression in Periodontal Ligament Cells and Modulates MMP-2 and MMP-13 Activity in Osteoblasts.  Bone and Tissue Regeneration Insights   2010  4:1-10    DOI: 10.4137/BTRI.S8120
7972  Wang X, Ito A, Sogo Y, Li X, Oyane A.  Silicate-apatite composite layers on external fixation rods and in vitro evaluation using fibroblast and osteoblast.  J Biomed Mater Res A  2010  92(3):1181-9  PubMed ID: 19322819   DOI: 10.1002/jbm.a.32436
7992  Hsien-Te Chen, Chi-Jen Chung, Tsai-Ching Yang, I-Ping Chiang, Chin-Hsin Tang, Keh-Chang Chen, Ju-Liang He  Osteoblast growth behavior on micro-arc oxidized β-titanium alloy  Surface and Coatings Technology   2010  205:1624-1629    DOI: 10.1016/j.surfcoat.2010.07.027
8187  Xu Xu Bao, Yuan Li, Akira Teramoto, Koji Abe  Carboxymethyl Chitosan/Hydroxyapatite Composite Scaffold for Bone Regeneration  Advanced Materials Research  2010  123-125:299-302    DOI: 10.4028/
8189  Shinoda Y, Kawaguchi H, Higashikawa A, Hirata M, Miura T, Saito T, Nakamura K, Chung UI, Ogata N.  Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells.  J Cell Biochem  2010  109(4):755-63  PubMed ID: 20058231   DOI: 10.1002/jcb.22454
8190  Jun-Ichi Sasaki, Takuya Matsumoto, Hiroshi Egusa, Takayoshi Nakano, Takuya Ishimoto, Taiji Sohmura and Hirofumi Yatani   In vitro engineering of transitional tissue by patterning and functional control of cells in fibrin gel  Soft Matter  2010  6:1662-1667    DOI: 10.1039/B922418A
8191  Young Min Shin, Heungsoo Shin & Youn Mook Lim   Surface modification of electrospun poly(L-lactide-co-ɛ-caprolactone) fibrous meshes with a RGD peptide for the control of adhesion, proliferation and differentiation of the preosteoblastic cells  Macromolecular Research  2010  18:472–481    DOI: 10.1007/s13233-010-0507-z
8194  Xiupeng Wang, Xia Li a, Kazuo Onuma, Atsuo Ito, Yu Sogo, Katsunori Kosuge and Ayako Oyane  Mesoporous bioactive glass coatings on stainless steel for enhanced cell activity, cytoskeletal organization and AsMg immobilization  J Mater Chem  2010  20:6437-6445    DOI: 10.1039/C0JM00399A
8195  Widyowati R, Tezuka Y, Miyahara T, Awale S, Kadota S.  Alkaline phosphatase (ALP) enhancing iridoid glucosides from the Indonesian medicinal plant Barleria lupulina.  Nat Prod Commun  2010  5(11):1711-6  PubMed ID: 21213964  
8197  Takaaki ArahiraMitsugu Todo  Effects of osteoblast-like cell seeding on mechanical properties of porous composite scaffolds  6th World Congress of Biomechanics (WCB 2010)  2010  1234-1237    DOI: 10.1007/978-3-642-14515-5_313
8200  Megumi FUSE, Tohru HAYAKAWA, Masahiko FUKUMOTO, Masaharu MAKIMURA  Effect of fibronectin immobilization on poly-L-lactic acid films for the adhesion and proliferation of mouse osteoblast-like cells  Nano Biomedicine  2010  2:93-102    DOI: 10.11344/nano.2.93
8201  Sasaki J, Asoh TA, Matsumoto T, Egusa H, Sohmura T, Alsberg E, Akashi M, Yatani H.  Fabrication of three-dimensional cell constructs using temperature-responsive hydrogel.  Tissue Eng Part A  2010  16(8):2497-504  PubMed ID: 20218862   DOI: 10.1089/ten.TEA.2009.0523
8207  Kaori Yoshino, Kaoru Saijo, Chikako Noro and Yukio Nakamura  Development of a simple method to determine the mouse strain from which cultured cell lines originated  Interdisciplinary Bio Central   2010  2:0014    DOI: 10.4051/ibc.2010.2.4.0014
8212  Chatterjee K, Lin-Gibson S, Wallace WE, Parekh SH, Lee YJ, Cicerone MT, Young MF, Simon CG Jr.  The effect of 3D hydrogel scaffold modulus on osteoblast differentiation and mineralization revealed by combinatorial screening.  Biomaterials  2010  31(19):5051-62  PubMed ID: 20378163   DOI: 10.1016/j.biomaterials.2010.03.024
8235  Kawamori Y, Katayama Y, Asada N, Minagawa K, Sato M, Okamura A, Shimoyama M, Nakagawa K, Okano T, Tanimoto M, Kato S, Matsui T.  Role for vitamin D receptor in the neuronal control of the hematopoietic stem cell niche.  Blood  2010  116(25):5528-35  PubMed ID: 20813899   DOI: 10.1182/blood-2010-04-279216
8236  Zhou WY, Guo B, Liu M, Liao R, Rabie AB, Jia D.  Poly(vinyl alcohol)/halloysite nanotubes bionanocomposite films: Properties and in vitro osteoblasts and fibroblasts response.  J Biomed Mater Res A.   2010  93(4):1574-87  PubMed ID: 20014291   DOI: 10.1002/jbm.a.32656
8255  Inoue M, Rodriguez AP, Takagi T, Katase N, Kubota M, Nagai N, Nagatsuka H, Inoue M, Nagaoka N, Takagi S, Suzuki K.  Effect of a new titanium coating material (CaTiO3-aC) prepared by thermal decomposition method on osteoblastic cell response.  J Biomater Appl  2010  24(7):657-72  PubMed ID: 19726530   DOI: 10.1177/0885328209340334
8256  Eun-Hye Lee, Yoshiki Kamigaito, Takashi Tsujimoto, Shu Seki, Hiroshi Uyama, Seiichi Tagawa, Moon-Hee Sung  Preparation of Poly (γ-glutamic acid) Hydrogel/Apatite Composites and Their Application forScaffold of Cell Proliferation  SENI GAKKAISHI  2010  66:104-111    DOI: 10.2115/fiber.66.104
8262  Zhao J, Ohba S, Komiyama Y, Shinkai M, Chung UI, Nagamune T.  Icariin: a potential osteoinductive compound for bone tissue engineering.  Tissue Eng Part A  2010  16(1):233-43  PubMed ID: 19698057   DOI: 10.1089/ten.TEA.2009.0165
8266  Takeuchi K, Abe M, Hiasa M, Oda A, Amou H, Kido S, Harada T, Tanaka O, Miki H, Nakamura S, Nakano A, Kagawa K, Yata K, Ozaki S, Matsumoto T.  Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth.  PLoS One  2010  5(3):e9870  PubMed ID: 20360846   DOI: 10.1371/journal.pone.0009870
8271  Sezin Aday Menemşe Gümüşderelioğlu  Bone‐like apatite‐coated chitosan scaffolds: Characterization and osteoblastic activity  Polymer Composites  2010  31:1418-1426    DOI: 10.1002/pc.20927
15466  Toshihiko Shiraishi, Kazuhiro Sakata, Shin Morishita, Ryohei Takeuchi  Visualization of Actin Fibers in a Living Osteoblast Under Shear Deformation  Biomedical and Biotechnology Engineering  2010  2    DOI: 10.1115/imece2010-39810
15690  M. Lebourg, J. Suay Antón, J.L. Gomez Ribelles  Characterization of calcium phosphate layers grown on polycaprolactone for tissue engineering purposes  Composites Science and Technology  2010  70:1796-1804    DOI: 10.1016/j.compscitech.2010.07.017
17405  Sezin Aday, Menemşe Gümüşderelioğlu  Bone-like apatite-coated chitosan scaffolds: Characterization and osteoblastic activity  Polymer Composites  2010     
8408  Sailon AM, Allori AC, Davidson EH, Reformat DD, Allen RJ, Warren SM.  A novel flow-perfusion bioreactor supports 3D dynamic cell culture.  J. Biomed. Biotechnol.  2009  2009:873816  PubMed ID: 20037739   DOI: 10.1155/2009/873816
8410  Hsien-Te Chena, Ching-Hung Hsiaoa, Han-Yun Longa, Chi- Jen Chungc, Chih-Hsin Tangd, Keh-Chang Chena, Ju-Liang Hea  Micro-arc oxidation of β-titanium alloy: Structural characterization and osteoblast compatibility  Surface and Coatings Technology  2009  204:1126-1131    DOI: 10.1016/j.surfcoat.2009.06.043
8441  Kamon M, Zhao R, Sakamoto K.  Green tea polyphenol (-)-epigallocatechin gallate suppressed the differentiation of murine osteoblastic MC3T3-E1 cells.  Cell Biol. Int.  2009  34:109-16  PubMed ID: 19947947   DOI: 10.1042/CBI20090011
8444  Hsi-Kai Tsoua, Ping- Yen Hsieha, Chi-Jen Chung, Chih-Hsin Tang, Tien-Wei Shyr, ju-LiangHe  Low-temperature deposition of anatase TiO2 on medical grade polyetheretherketone to assist osseous integration  Surface and Coatings Technology  2009  204:1121-1125    DOI: 10.1016/j.surfcoat.2009.06.018
8451  Takahashi S, Yamazoe H, Sassa F, Suzuki H, Fukuda J.  Preparation of coculture system with three extracellular matrices using capillary force lithography and layer-by-layer deposition.  J. Biosci. Bioeng.  2009  108:544-50  PubMed ID: 19914591   DOI: 10.1016/j.jbiosc.2009.06.013
8483  LEE Seung-Jae, LEE In Hwan, PARK Jeong Hun, GWAK So-Jung, RHIE Jong-Won, CHO Dong-Woo, KO Tae Jo & KIM Dong Sung  Development of a hybrid scaffold and a bioreactor for cartilage regeneration  Chinese Science Bulletin  2009  54:3608-3612    DOI: 10.1007/s11434-009-0602-8
8498  Yamasaki K, Hagiwara H.  Excess iron inhibits osteoblast metabolism.  Toxicol. Lett.  2009  191:211-5  PubMed ID: 19735707   DOI: 10.1016/j.toxlet.2009.08.023
8501  Kasai T, Bandow K, Suzuki H, Chiba N, Kakimoto K, Ohnishi T, Kawamoto S, Nagaoka E, Matsuguchi T.  Osteoblast differentiation is functionally associated with decreased AMP kinase activity.  J. Cell. Physiol.  2009  221:740-9  PubMed ID: 19725053   DOI: 10.1002/jcp.21917
8507  Yang JY, Jung JY, Cho SW, Choi HJ, Kim SW, Kim SY, Kim HJ, Jang CH, Lee MG, Han J, Shin CS.  Chloride intracellular channel 1 regulates osteoblast differentiation.  Bone  2009  45:1175-85  PubMed ID: 19703605   DOI: 10.1016/j.bone.2009.08.012
8508  Fernandes H, Dechering K, Van Someren E, Steeghs I, Apotheker M, Leusink A, Bank R, Janeczek K, Van Blitterswijk C, de Boer J.  The role of collagen crosslinking in differentiation of human mesenchymal stem cells and MC3T3-E1 cells.  Tissue Eng Part A  2009  15:3857-67  PubMed ID: 19694522   DOI: 10.1089/ten.tea.2009.0011
8524  Akihisa Kamikawa, Ying Li, Yoshimitsu Abiko  Hydrogen Peroxide Reduced Osteomodulin Gene Expression in MC3T3-E1  J Hard Tissue Biology  2009  18:59-62    DOI: 10.2485/jhtb.18.59
8538  Okamoto A, Ohnishi T, Bandow K, Kakimoto K, Chiba N, Maeda A, Fukunaga T, Miyawaki S, Matsuguchi T.  Reduction of orthodontic tooth movement by experimentally induced periodontal inflammation in mice.  Eur. J. Oral Sci.  2009  117:238-47  PubMed ID: 19583750   DOI: 10.1111/j.1600-0722.2009.00625.x
8565  Nagata A, Tanaka T, Minezawa A, Poyurovsky M, Mayama T, Suzuki S, Hashimoto N, Yoshida T, Suyama K, Miyata A, Hosokawa H, Nakayama T, Tatsuno I.  cAMP activation by PACAP/VIP stimulates IL-6 release and inhibits osteoblastic differentiation through VPAC2 receptor in osteoblastic MC3T3 cells.  J. Cell. Physiol.  2009  221:75-83  PubMed ID: 19496170   DOI: 10.1002/jcp.21831
8572  Itoh T, Nozawa Y, Akao Y.  MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5.  J. Biol. Chem.  2009  284:19272-9  PubMed ID: 19454767   DOI: 10.1074/jbc.M109.014001
8581  Maki M, Miyazaki H, Niisato N, Morihara T, Marunaka Y, Kubo T.  Blockers of K+/Cl- transporter/channels diminish proliferation of osteoblastic cells.  Biomed. Res.  2009  30:137-40  PubMed ID: 19420738   DOI: 10.2220/biomedres.30.137
8587  Tung NH, Ding Y, Choi EM, Van Kiem P, Van Minh C, Kim YH.  New anthracene glycosides from Rhodomyrtus tomentosa stimulate osteoblastic differentiation of MC3T3-E1 cells.  Arch. Pharm. Res.  2009  32:515-20  PubMed ID: 19407968   DOI: 10.1007/s12272-009-1406-8
8588  Nakao Y, Koike T, Ohta Y, Manaka T, Imai Y, Takaoka K.  Parathyroid hormone enhances bone morphogenetic protein activity by increasing intracellular 3', 5'-cyclic adenosine monophosphate accumulation in osteoblastic MC3T3-E1 cells.  Bone  2009  44:872-7  PubMed ID: 19442611   DOI: 10.1016/j.bone.2009.01.370
8618  Jin Woo Leea, GeunSeon Ahna, Dae Shick Kimb, Dong-Woo Cho  Development of nano- and microscale composite 3D scaffolds using PPF/DEF-HA and micro-stereolithography  Microelectronic Engineering  2009  86:1465-1467    DOI: 10.1016/j.mee.2008.12.038
8628  Dorsey SM, Lin-Gibson S, Simon CG Jr.  X-ray microcomputed tomography for the measurement of cell adhesionand proliferation in polymer scaffolds.  Biomaterials  2009  30:2967-74  PubMed ID: 19286251   DOI: 10.1016/j.biomaterials.2009.02.032
8629  Hou CH, Lin J, Huang SC, Hou SM, Tang CH.  Ultrasound stimulates NF-kappaB activation and iNOS expression via the Ras/Raf/MEK/ERK signaling pathway in cultured preosteoblasts.  J. Cell. Physiol.  2009  220:196-203  PubMed ID: 19288477   DOI: 10.1002/jcp.21751
8632  Kinugawa M, Fukuzawa S, Tachibana K.  Skeletal protein protection: the mode of action of an anti-osteoporotic marine alkaloid, norzoanthamine.  J. Bone Miner. Metab.  2009  27:303-14  PubMed ID: 19277454   DOI: 10.1007/s00774-009-0049-7
8634  Raynor JE, Petrie TA, Fears KP, Latour RA, Garcia AJ, Collard DM.  Saccharide polymer brushes to control protein and cell adhesion to titanium.  Biomacromolecules  2009  10:748-55  PubMed ID: 19271753   DOI: 10.1021/bm8011924
8638  Cho SW, Yang JY, Sun HJ, Jung JY, Her SJ, Cho HY, Choi HJ, Kim SW, Kim SY, Shin CS.  Wnt inhibitory factor (WIF)-1 inhibits osteoblastic differentiation in mouse embryonic mesenchymal cells.  Bone  2009  44:1069-77  PubMed ID: 19254785   DOI: 10.1016/j.bone.2009.02.012
8645  Yuan Q, Kubo T, Doi K, Morita K, Takeshita R, Katoh S, Shiba T, Gong P, Akagawa Y.  Effect of combined application of bFGF and inorganic polyphosphate on bioactivities of osteoblasts and initial bone regeneration.  Acta Biomater  2009  5:1716-24  PubMed ID: 19251495   DOI: 10.1016/j.actbio.2009.01.034
8649  Siddappa R, Mulder W, Steeghs I, van de Klundert C, Fernandes H, Liu J, Arends R, van Blitterswijk C, de Boer J.  cAMP/PKA signaling inhibits osteogenic differentiation and bone formation in rodent models.  Tissue Eng Part A  2009  15:2135-43  PubMed ID: 19231969   DOI: 10.1089/ten.tea.2008.0512
8656  Wada Y, Mizuno M, Tamura M.  Enamel matrix derivative neutralized the effect of lipopolysaccharide on osteoprotegerin and receptor activator of nuclear factor kappa B ligand expression of osteoblasts.  Arch. Oral Biol.  2009  54:306-12  PubMed ID: 19201394   DOI: 10.1016/j.archoralbio.2009.01.004
8662  Yoshida T, Clark MF, Stern PH.  The small GTPase RhoA is crucial for MC3T3-E1 osteoblastic cell survival.  J. Cell. Biochem.  2009  106:896-902  PubMed ID: 19184980   DOI: 10.1002/jcb.22059
8664  Lovmand J, Justesen J, Foss M, Lauridsen RH, Lovmand M, Modin C, Besenbacher F, Pedersen FS, Duch M.  The use of combinatorial topographical libraries for the screening of enhanced osteogenic expression and mineralization.  Biomaterials  2009  30:2015-22  PubMed ID: 19178942   DOI: 10.1016/j.biomaterials.2008.12.081
8671  Tung NH, Ding Y, Choi EM, Minh CV, Kim YH.  New neolignan component from Camellia amplexicaulis and effects on osteoblast differentiation.  Chem. Pharm. Bull.  2009  57:65-8  PubMed ID: 19122318   DOI: 10.1248/cpb.57.65
8685  Tohru Hayakawa, Chihiro Mochizuki, Hiroki Hara, Tadao Fukushima, Fei Yang, Hong Shen, Shenguo Wang, Mitsunobu Sato  Influence of Apatite Crystallinity in Porous PLGA/Apatite Composite Scaffold on Cortical Bone Response  J Hard Tissue Biology  2009  18:7-12   
8686  Yasuhiro Tanimoto, Yo Shibata, Asuka Murakami, Takashi Miyazaki, Norihiro Nishiyama  Effect of Varying HAP/TCP Ratios in Tape-cast Biphasic Calcium Phosphate Ceramics on Response In Vitro  J Hard Tissue Biology  2009  18:71-76    DOI: 10.2485/jhtb.18.71
8692  Kim YH, Choi EM.  Stimulation of osteoblastic differentiation and inhibition of interleukin-6 and nitric oxide in MC3T3-E1 cells by pomegranate ethanol extract.  Phytother Res  2009  23:737-9  PubMed ID: 19107859   DOI: 10.1002/ptr.2587
8708  Matsuguchi T, Chiba N, Bandow K, Kakimoto K, Masuda A, Ohnishi T.  JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation.  J. Bone Miner. Res.  2009  24:398-410  PubMed ID: 19016586   DOI: 10.1359/jbmr.081107
8766  Yamachika E, Tsujigiwa H, Shirasu N, Ueno T, Sakata Y, Fukunaga J, Mizukawa N, Yamada M, Sugahara T.  Immobilized recombinant human bone morphogenetic protein-2 enhances the phosphorylation of receptor-activated Smads.  J Biomed Mater Res A  2009  88:599-607  PubMed ID: 18314893   DOI: 10.1002/jbm.a.31833
6536  Kanamoto T, Mizuhashi K, Terada K, Minami T, Yoshikawa H, Furukawa T.  Isolation and characterization of a novel plasma membrane protein, osteoblast induction factor (obif), associated with osteoblast differentiation.  BMC Dev Biol  2009  9:70  PubMed ID: 20025746   DOI: 10.1186/1471-213X-9-70
7575  Oya K, Tanaka Y, Saito H, Kurashima K, Nogi K, Tsutsumi H, Tsutsumi Y, Doi H, Nomura N, Hanawa T.  Calcification by MC3T3-E1 cells on RGD peptide immobilized on titanium through electrodeposited PEG.  Biomaterials.   2009  30(7):1281-6  PubMed ID: 19091397   DOI: 10.1016/j.biomaterials.2008.11.030
7880  Bu SY, Hunt TS, Smith BJ.  Dried plum polyphenols attenuate the detrimental effects of TNF-alpha on osteoblast function coincident with up-regulation of Runx2, Osterix and IGF-I.  J Nutr Biochem  2009  20(1):35-44  PubMed ID: 18495459   DOI: 10.1016/j.jnutbio.2007.11.012
7942  Nakai T, Yoshimura Y, Deyama Y, Suzuki K, Iida J.  Mechanical stress up-regulates RANKL expression via the VEGF autocrine pathway in osteoblastic MC3T3-E1 cells.  Mol Med Rep  2009  2(2):229-34  PubMed ID: 21475817   DOI: 10.3892/mmr_00000088
7961  Wang X, Ito A, Sogo Y, Li X, Tsurushima H, Oyane A.  Ascorbate-apatite composite and ascorbate-FGF-2-apatite composite layers formed on external fixation rods and their effects on cell activity in vitro.  Acta Biomater  2009  5(7):2647-56  PubMed ID: 19375998   DOI: 10.1016/j.actbio.2009.03.020
7973  Tokuda S, Obata A, Kasuga T.  Preparation of poly(lactic acid)/siloxane/calcium carbonate composite membranes with antibacterial activity.  Acta Biomater  2009  5(4):1163-8  PubMed ID: 18996778   DOI: 10.1016/j.actbio.2008.10.005
7985  Ding Y, Nguyen HT, Choi EM, Bae K, Kim YH.  Rhusonoside A, a new megastigmane glycoside from Rhus sylvestris, increases the function of osteoblastic MC3T3-E1 cells.  Planta Med  2009  75(2):158-62  PubMed ID: 19053017   DOI: 10.1055/s-0028-1088373
7989  Yun SI, Yoon HY, Jeong SY, Chung YS.  Glucocorticoid induces apoptosis of osteoblast cells through the activation of glycogen synthase kinase 3beta.  J Bone Miner Metab  2009  27(2):140-8  PubMed ID: 19066717   DOI: 10.1007/s00774-008-0019-5
7991  Jin WooLee, Jin Hwa Jung, Dae Shick Kim, Geunbae Lim, Dong-Woo Cho  Estimation of cell proliferation by various peptide coating at the PPF/DEF 3D scaffold  Microelectronic Engineering  2009  86:1451-1454    DOI: 10.1016/j.mee.2008.12.052
10145  Murakami M, Kawachi H, Ogawa K, Nishino Y, Funaba M.  Receptor expression modulates the specificity of transforming growth factor-beta signaling pathways.  Genes Cells  2009  14(4):469-82  PubMed ID: 19335617   DOI: 10.1111/j.1365-2443.2009.01283.x
7993  Akiyama H, Furukawa S, Wakisaka S, Maeda T.  Elevated expression of CTRP3/cartducin contributes to promotion of osteosarcoma cell proliferation.  Oncol Rep  2009  21(6):1477-81  PubMed ID: 19424626   DOI: 10.3892/or_00000377
7994  Zheng Z, Zhang L, Kong L, Wang A, Gong Y, Zhang X.  The behavior of MC3T3-E1 cells on chitosan/poly-L-lysine composite films: effect of nanotopography, surface chemistry, and wettability.  J Biomed Mater Res A  2009  89(2):453-65  PubMed ID: 18431777   DOI: 10.1002/jbm.a.31979
8008  Mariona Rabionet Jay Arre Toque Ari Ide‐Ektessabi  In vitro evaluation of osteoblast‐like cells on hydroxyapatite‐coated porous stainless steel implants by synchrotron radiation x‐ray fluorescence  X-Ray Spectrometry  2009  38:278-282    DOI: 10.1002/xrs.1164
8009  Chiaki HIWA, Yoshikazu NAKAI, Nobuo TANAKA, Taiji ADACHI, Masaki HOJO, Shunsuke BABA  512 Evaluation of Mechanical and Cell-proliferative Properties on In vitro Using Different types of Biodegradable Polymer as Scaffold  The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME  2009  2008.21:207-208    DOI: 10.1299/jsmebio.2008.21.207
8013  Higuchi C, Nakamura N, Yoshikawa H, Itoh K.  Transient dynamic actin cytoskeletal change stimulates the osteoblastic differentiation.  J Bone Miner Metab  2009  27(2):158-67  PubMed ID: 19183835   DOI: 10.1007/s00774-009-0037-y
8014  Takeshi Hagio, Tomohiko Tanase, Jun Akiyama, Masanori Umino, Kazuhiko Iwai, Shigeo Asai  Difference in bioactivity, initial cell attachment and cell morphology observed on the surface of hydroxyapatite ceramics with controlled orientation  MATERIALS TRANSACTIONS  2009  50:734-739    DOI: 10.2320/matertrans.MBW200836
8032  Yamazaki M, Fukushima H, Shin M, Katagiri T, Doi T, Takahashi T, Jimi E.  Tumor necrosis factor alpha represses bone morphogenetic protein (BMP) signaling by interfering with the DNA binding of Smads through the activation of NF-kappaB.  J Biol Chem  2009  284(51):35987-95  PubMed ID: 19854828   DOI: 10.1074/jbc.M109.070540
8034  Wu PH1, Arce SH, Burney PR, Tseng Y.  A novel approach to high accuracy of video-based microrheology.  Biophys J.  2009  96(12):5103-11  PubMed ID: 19527670   DOI: 10.1016/j.bpj.2009.03.029
8037  Lin NJ, Lin-Gibson S.  Osteoblast response to dimethacrylate composites varying in composition, conversion and roughness using a combinatorial approach.  Biomaterials  2009  30(27):4480-7  PubMed ID: 19520423   DOI: 10.1016/j.biomaterials.2009.05.019
8086  Hayashi C, Hasegawa U, Saita Y, Hemmi H, Hayata T, Nakashima K, Ezura Y, Amagasa T, Akiyoshi K, Noda M.  Osteoblastic bone formation is induced by using nanogel-crosslinking hydrogel as novel scaffold for bone growth factor.  J Cell Physiol  2009  220(1):1-7  PubMed ID: 19301257   DOI: 10.1002/jcp.21760
8089  Zheng Z, Wei Y, Wang G, Gong Y, Zhang X.  Surface characterization and cytocompatibility of three chitosan/polycation composite membranes for guided bone regeneration.  J Biomater Appl  2009  24(3):209-29  PubMed ID: 18987023   DOI: 10.1177/0885328208095825
8103  Young-Joon Seol, Jong Young Kim, Eui Kyun Park, Shin-YoonKim, Dong-Woo Cho  Fabrication of a hydroxyapatite scaffold for bone tissue regeneration using microstereolithography and molding technology  Microelectronic Engineering  2009  86:1443-1446    DOI: 10.1016/j.mee.2009.01.053
8123  Cheung CL, Chan BY, Chan V, Ikegawa S, Kou I, Ngai H, Smith D, Luk KD, Huang QY, Mori S, Sham PC, Kung AW.  Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.  Hum Mol Genet  2009  18(4):679-87  PubMed ID: 19064610   DOI: 10.1093/hmg/ddn397
8131  Mavis B, Demirtaş TT, Gümüşderelioğlu M, Gündüz G, Colak U.  Synthesis, characterization and osteoblastic activity of polycaprolactone nanofibers coated with biomimetic calcium phosphate.  Acta Biomater  2009  5(8):3098-111  PubMed ID: 19426840   DOI: 10.1016/j.actbio.2009.04.037
8140  Aamer KA, Genson KL, Kohn J, Becker ML.  Impact of polymer-bound iodine on fibronectin adsorption and osteoblast cell morphology in radiopaque medical polymers: tyrosine-derived polycarbonate blends as a model system.  Biomacromolecules  2009  10(9):2418-26  PubMed ID: 19645443   DOI: 10.1021/bm900327b
8141  Rodríguez Hernández JC, Rico P, Moratal D, Monleón Pradas M, Salmerón-Sánchez M.  Fibrinogen patterns and activity on substrates with tailored hydroxy density.  Macromol Biosci  2009  ;9(8):766-75  PubMed ID: 19422014   DOI: 10.1002/mabi.200800332
8145  Işil Gerçek Beşkardeş, Menemşe Gümüşderelioğlu  Biomimetic Apatite-coated PCL Scaffolds: Effect of Surface Nanotopography on Cellular Functions  Journal of Bioactive and Compatible Polymers  2009  24:507-524    DOI: 10.1177/0883911509349311
15463  Seung-Jae Lee, Jeong Hun Park, Yong-Joon Seol, In Hwan Lee, Sang Soon Kang, Dong-Woo Cho  Development of a bioreactor for the mechanical stimulation of agarose hydrogels  Microelectronic Engineering  2009  86:1411-1415    DOI: 10.1016/j.mee.2009.02.026
15464  Toshihiko Shiraishi, Tetsuo Shikata, Shin Morishita, Ryohei Takeuchi  Investigation of Promotion of Bone Matrices in Cultured Osteoblasts by Mechanical Vibration  Biomedical and Biotechnology Engineering  2009  2    DOI: 10.1115/imece2009-11131
15465  Yin Tintut  Oxidized Phospholipids Regulate Interleukin-6 Expression via the Protein Kinase A and Extracellular Signal-regulated Pathways in Osteoblasts  The UCLA USJ  2009  22:57-64   
17406  Li X, Ominsky MS, Warmington KS, Morony S, Gong J, Cao J, Gao Y, Shalhoub V, Tipton B, Haldankar R, Chen Q, Winters A, Boone T, Geng Z, Niu QT, Ke HZ, Kostenuik PJ, Simonet WS, Lacey DL, Paszty C.  Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis  J Bone Miner Res  2009  24(4):578-88  PubMed ID: 19049336   DOI: 10.1359/jbmr.081206
8714  Yamamichi N, Pugdee K, Chang WJ, Lee SY, Yoshinari M, Hayakawa T, Abiko Y.  Gene expression monitoring in osteoblasts on titanium coated with fibronectin-derived peptide.  Dent Mater J  2008  27:744-50  PubMed ID: 18972793   DOI: 10.4012/dmj.27.744
8724  Schulz RM, Wustneck N, van Donkelaar CC, Shelton JC, Bader A.  Development and validation of a novel bioreactor system for load- and perfusion-controlled tissue engineering of chondrocyte-constructs.  Biotechnol. Bioeng.  2008  101:714-28  PubMed ID: 18814291   DOI: 10.1002/bit.21955
8727  Yamauchi M, Kawai S, Kato T, Ooshima T, Amano A.  Odd-skipped related 1 gene expression is regulated by Runx2 and Ikzf1 transcription factors.  Gene  2008  426:81-90  PubMed ID: 18804520   DOI: 10.1016/j.gene.2008.08.015
8734  Van Kiem P, Quang TH, Huong TT, Nhung le TH, Cuong NX, Van Minh C, Choi EM, Kim YH.  Chemical constituents of Acanthus ilicifolius L. and effect on osteoblastic MC3T3E1 cells.  Arch. Pharm. Res.  2008  31:823-9  PubMed ID: 18704321   DOI: 10.1007/s12272-001-1232-3
8743  Cuong NX, Tuan TA, Kiem PV, Minh CV, Choi EM, Kim YH.  New cembranoid diterpenes from the Vietnamese soft coral Sarcophyton mililatensis stimulate osteoblastic differentiation in MC3T3-E1 cells.  Chem. Pharm. Bull.  2008  56:988-92  PubMed ID: 18591816   DOI: 10.1248/cpb.56.988
8779  Ohki TOMOMATSU, Akira TACHIBANA, Kiyoshi YAMAUCHI and Toshizumi TANABE  A film of collagen/calcium phosphate composite prepared by enzymatic mineralization in an aqueous phase  J The Ceramic Society of Japan  2008  116:10-13    DOI: 10.2109/jcersj2.116.10
6300  Shimomura-Kuroki J, Ubaidus S, Hl Freitas P, Li M, Ishida Y, Saito N, Oda K, Shimooka S, Amizuka N.  Rat wild-type parathyroid hormone receptor (PTH-R) and mutant PTH-R(P132L) show the different intracellular localization in vitro.  Biomed Res  2008  29(2):61-9  PubMed ID: 18480546   DOI: 10.2220/biomedres.29.61
6521  Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H.  Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9.  J Biol Chem  2008  283(36):24682-9  PubMed ID: 18617520   DOI: 10.1074/jbc.M709857200
6528  Arai K, Nagashima Y, Takemoto T, Nishiyama T.  Mechanical strain increases expression of type XII collagen in murine osteoblastic MC3T3-E1 cells.  Cell Struct Funct  2008  33(2):203-10  PubMed ID: 18957791   DOI: 10.1247/csf.08025
6529  Miyazaki T, Miyauchi S, Tawada A, Anada T, Matsuzaka S, Suzuki O.  Oversulfated chondroitin sulfate-E binds to BMP-4 and enhances osteoblast differentiation.  J Cell Physiol  2008  217(3):769-77  PubMed ID: 18720384   DOI: 10.1002/jcp.21557
7647  Ozeki K, Aoki H, Fukui Y.  The effect of adsorbed vitamin D and K to hydroxyapatite on ALP activity of MC3T3-E1 cell.  J Mater Sci Mater Med  2008  19(4):1753-7  PubMed ID: 17943413   DOI: 10.1007/s10856-007-3288-y
7660  Tamura D, Hiraga T, Myoui A, Yoshikawa H, Yoneda T.  Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone.  Int J Oncol  2008  33(1):17-24  PubMed ID: 18575746  
7697  Xu HH, Weir MD, Simon CG.  Injectable and strong nano-apatite scaffolds for cell/growth factor delivery and bone regeneration.  Dent Mater  2008  24(9):1212-22  PubMed ID: 18359072   DOI: 10.1016/
7709  Wong RW, Rabie AB.  Effect of quercetin on preosteoblasts and bone defects.  Open Orthop J  2008  2:27-32  PubMed ID: 19461927   DOI: 10.2174/1874325000802010027
7715  Maekawa K, Yoshida Y, Mine A, van Meerbeek B, Suzuki K, Kuboki T.  Effect of polyphosphoric acid pre-treatment of titanium on attachment, proliferation, and differentiation of osteoblast-like cells (MC3T3-E1).  Clin Oral Implants Res  2008  19(3):320-5  PubMed ID: 18190561   DOI: 10.1111/j.1600-0501.2007.01477.x
7716  Chen RI, Gallant ND, Smith JR, Kipper MJ, Simon CG Jr.  Time-dependent effects of pre-aging polymer films in cell culture medium on cell adhesion and spreading.  J Mater Sci Mater Med  2008  19(4):1759-66  PubMed ID: 18049876   DOI: 10.1007/s10856-007-3309-x
7723  Cho SW, Her SJ, Sun HJ, Choi OK, Yang JY, Kim SW, Kim SY, Shin CS.  Differential effects of secreted frizzled-related proteins (sFRPs) on osteoblastic differentiation of mouse mesenchymal cells and apoptosis of osteoblasts.  Biochem Biophys Res Commun  2008  367(2):399-405  PubMed ID: 18166153   DOI: 10.1016/j.bbrc.2007.12.128
7724  Tetsuo SHIKATA, Toshihiko SHIRAISHI, Shin MORISHITA, Ryohei TAKEUCHI, Tomoyuki SAITO  Effects of amplitude and frequency of mechanical vibration stimulation on cultured osteoblasts  Journal of System Design and Dynamics  2008  2:382-388    DOI: 10.1299/jsdd.2.382
7730  Zhao J, Ohba S, Shinkai M, Chung UI, Nagamune T.  Icariin induces osteogenic differentiation in vitro in a BMP- and Runx2-dependent manner.  Biochem Biophys Res Commun  2008  369(2):444-8  PubMed ID: 18295595   DOI: 10.1016/j.bbrc.2008.02.054
7740  Yong HUANG, Yingjun WANG, Chengyun NING, Kaihui NANa, Yong HAN  Preparation and properties of a cerium-containing hydroxyapatite coating on commercially pure titanium by micro-arc oxidation  Rare Metals   2008  27:257-260    DOI: 10.1016/S1001-0521(08)60125-4
7748  Eelen G, Vanden Bempt I, Verlinden L, Drijkoningen M, Smeets A, Neven P, Christiaens MR, Marchal K, Bouillon R, Verstuyf A.  Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy.  Oncogene  2008  ;27(30):4233-41  PubMed ID: 18345034   DOI: 10.1038/onc.2008.51
7768  Jie Mo Tian, Li Min Dong, Chen Wang, Zhi Ping Guo, Chao Zong Zhang, Qing Fen Zan, Xian Gang Wang  Tissue engineering scaffolds of bioceramics and new bone growth  Key Engineering Materials  2008  368-372:1161-1165    DOI: 10.4028/
7772  Morgan AW, Roskov KE, Lin-Gibson S, Kaplan DL, Becker ML, Simon CG Jr.  Characterization and optimization of RGD-containing silk blends to support osteoblastic differentiation.  Biomaterials  2008  29(16):2556-63  PubMed ID: 18325585   DOI: 10.1016/j.biomaterials.2008.02.007
7775  Saito K, Konishi I, Nishiguchi M, Hoshino T, Fujiwara T.  Amelogenin binds to both heparan sulfate and bone morphogenetic protein 2 and pharmacologically suppresses the effect of noggin.  Bone  2008  43(2):371-6  PubMed ID: 18515207   DOI: 10.1016/j.bone.2008.03.029
7807  Shibata Y, He LH, Toda Y, Kataoka Y, Fujisawa N, Miyazaki T, Swain MV.  Micromechanical evaluation of mineralized multilayers.  J Biomech  2008  41(16):3414-8  PubMed ID: 18995855   DOI: 10.1016/j.jbiomech.2008.09.018
7818  Chia-Hua Yang, Ying Li, Wei-Jen Chang, Duen-Jeng Wang, Sheng-Yang Lee, Yoshimitsu Abiko  Reduction of Early Growth Response-1 Gene Expression in Osteoblasts by Hydrogen Peroxide  Journal of Hard Tissue Biology  2008  17:31-34    DOI: 10.2485/jhtb.17.31
7824  Yasuda Y, Koike T, Kawamorita T, Saito T.  Adiponectin induces dentin sialophosphoprotein in rat dental pulp cells: an in vitro study.  J Endod  2008  34(6):679-83  PubMed ID: 18498888   DOI: 10.1016/j.joen.2008.02.038
7825  Yanyin Yang Durgadas Bolikal Matthew L. Becker Joachim Kohn Diana N. Zeiger Carl G. Simon Jr  Combinatorial polymer scaffold libraries for screening cell‐biomaterial interactions in 3D  Adv. Mater  2008  20:2037–2043    DOI: 10.1002/adma.200702088
7826  Wei YY, Chen YJ, Hsiao YC, Huang YC, Lai TH, Tang CH.  Osteoblasts-derived TGF-beta1 enhance motility and integrin upregulation through Akt, ERK, and NF-kappaB-dependent pathway in human breast cancer cells.  Mol Carcinog  2008  47(7):526-37  PubMed ID: 18161870   DOI: 10.1002/mc.20411
7830  Hidetaka Ishino, Yutaka Kawahito, Yasunori Tsubouchi, Masataka Kohno, Makoto Wada, Aihiro Yamamoto, Masahide Hamaguchi, Masatoshi Kadoya, Daisaku Tokunaga, Tatsuya Hojo, Masahide Matsuyama, Rikio Yoshimura, Toshikazu Yoshikawa  Feedback Control of the Arachidonate Cascade in Osteoblastic Cells by 15-deoxy-Δ12, 14-Prostaglandin J2  Journal of Clinical Biochemistry and Nutrition  2008  42:64-69  PubMed ID: 18231633   DOI: 10.3164/jcbn.2008011
7831  Ko EK, Jeong SI, Lee JH, Shin H.  Improvement of differentiation and mineralization of pre-osteoblasts on composite nanofibers of poly(lactic acid) and nanosized bovine bone powder.  Macromol Biosci  2008  8(12):1098-107  PubMed ID: 18781556   DOI: 10.1002/mabi.200800089
7832  Ishikuro M, Sakamoto K, Kayamori K, Akashi T, Kanda H, Izumo T, Yamaguchi A.  Significance of the fibrous stroma in bone invasion by human gingival squamous cell carcinomas.  Bone  2008  43(3):621-7  PubMed ID: 18585993   DOI: 10.1016/j.bone.2008.05.014
7839  Ryosuke OHNO, Naoko NAKAMURA, Chiaki HIWA, Kumiko YOKOTA, Yoshikazu NAKAI  A310 Relationship between internal structural size of the Scaffold and bone tissue regeneration  The Proceedings of the JSME Conference on Frontiers in Bioengineering  2008  19:99-100    DOI: 10.1299/jsmebiofro.2008.19.99
7844  Nakasaki M, Yoshioka K, Miyamoto Y, Sasaki T, Yoshikawa H, Itoh K.  IGF-I secreted by osteoblasts acts as a potent chemotactic factor for osteoblasts.  Bone  2008  43(5):869-79  PubMed ID: 18718566   DOI: 10.1016/j.bone.2008.07.241
7863  Maehira F1, Iinuma Y, Eguchi Y, Miyagi I, Teruya S.  Effects of soluble silicon compound and deep-sea water on biochemical and mechanical properties of bone and the related gene expression in mice.  J Bone Miner Metab  2008  26(5):446-55  PubMed ID: 18758902   DOI: 10.1007/s00774-007-0845-x
7864  Tanimoto Y, Shibata Y, Kataoka Y, Miyazaki T, Nishiyama N.  Osteoblast-like cell proliferation on tape-cast and sintered tricalcium phosphate sheets.  Acta Biomater  2008  4(2):397-402  PubMed ID: 18054299   DOI: 10.1016/j.actbio.2007.10.001
7865  Roelofsen T, Akkers R, Beumer W, Apotheker M, Steeghs I, van de Ven J, Gelderblom C, Garritsen A, Dechering K.  Sphingosine-1-phosphate acts as a developmental stage specific inhibitor of platelet-derived growth factor-induced chemotaxis of osteoblasts.  J Cell Biochem  2008  105(4):1128-38  PubMed ID: 18819098   DOI: 10.1002/jcb.21915
7877  Tamiya H, Ikeda T, Jeong JH, Saito T, Yano F, Jung YK, Ohba S, Kawaguchi H, Chung UI, Choi JY.  Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator.  Gene  2008  416(1-2):53-60  PubMed ID: 18442887   DOI: 10.1016/j.gene.2008.03.003
7878  Adachi T, Sato K, Higashi N, Tomita Y, Hojo M.  Simultaneous observation of calcium signaling response and membrane deformation due to localized mechanical stimulus in single osteoblast-like cells.  J Mech Behav Biomed Mater  2008  1(1):43-50  PubMed ID: 19627770   DOI: 10.1016/j.jmbbm.2007.06.003
7879  Oki Y, Watanabe S, Endo T, Kano K.  Mature adipocyte-derived dedifferentiated fat cells can trans-differentiate into osteoblasts in vitro and in vivo only by all-trans retinoic acid.  Cell Struct Funct  2008  33(2):211-22  PubMed ID: 19088398   DOI: 10.1247/csf.08038
7881  M. Casolaro, Y. Ito, T. Ishii, S. Bottari, F. Samperi, R. Mendichi  Stimuli-responsive poly(ampholyte)s containing L-histidine residues: synthesis and protonation thermodynamics of methacrylic polymers in the free and in the cross-linked gel forms  eXPRESS Polymer Letters  2008  2:165–183    DOI: 10.3144/expresspolymlett.2008.22
7897  Isao HIRATA, Masayuki OKAZAKI  Higher Concentrations of Fluoride Ions Dramatically Inhibit the Survival of Osteoblasts  Journal of Oral Tissue Engineering  2008  6:3-8    DOI: 10.11223/jarde.6.3
7904  Hosaka H, Nagata A, Yoshida T, Shibata T, Nagao T, Tanaka T, Saito Y, Tatsuno I.  Pancreatic polypeptide is secreted from and controls differentiation through its specific receptors in osteoblastic MC3T3-E1 cells.  Peptides  2008  29(8):1390-5  PubMed ID: 18440094   DOI: 10.1016/j.peptides.2008.03.015
7919  Nomura-Furuwatari C, Wakitani S, Hashimoto Y, Imai Y, Ohta Y, Nakagawa K, Nakao Y, Takayama K, Manaka T, Takaoka K.  Expression profiles of phosphodiesterase 4D splicing variants in osteoblastic cells.  J Bone Miner Metab  2008  26(2):152-8  PubMed ID: 18301971   DOI: 10.1007/s00774-007-0803-7
7939  Mori K, Blanchard F, Charrier C, Battaglia S, Ando K, Duplomb L, Shultz LD, Redini F, Heymann D.  Conditioned media from mouse osteosarcoma cells promote MC3T3-E1 cell proliferation using JAKs and PI3-K/Akt signal crosstalk.  Cancer Sci  2008  99(11):2170-6  PubMed ID: 18957057   DOI: 10.1111/j.1349-7006.2008.00919.x
7922  Alvarez K, Hyun SK, Fujimoto S, Nakajima H.  In vitro corrosion resistance of Lotus-type porous Ni-free stainless steels.  J Mater Sci Mater Med  2008  19(11):3385-97  PubMed ID: 18545945   DOI: 10.1007/s10856-008-3458-6
15462  Toshihiko Shiraishi, Takafumi Onishi, Shin Morishita, Ryohei Takeuchi  Measurement of Dynamic Viscoelasticity of an Osteoblast Under Adhesive Condition Using a Piezoelectric Vibrator  Biomedical and Biotechnology Engineering  2008      DOI: 10.1115/imece2008-67235
16613  Su-Jung Park  Chemical Observation of Anodic TiO2 for Biomaterial Application  Metals and Materials International  2008  14:449-455   
17403  Toda Y, Shibata Y, Kataoka Y, Kawawa T, Miyazaki T.  Interfacial assembly of bioinspired nanostructures mediated by supersensitive crystals  J Biomed Mater Res A  2008  84(4):869-74  PubMed ID: 17635033   DOI: 10.1002/jbm.a.31488
17404  Hojo H, Igawa K, Ohba S, Yano F, Nakajima K, Komiyama Y, Ikeda T, Lichtler AC, Woo JT, Yonezawa T, Takato T, Chung UI.  Development of high-throughput screening system for osteogenic drugs using a cell-based sensor  Biochem Biophys Res Commun  2008  376(2):375-9  PubMed ID: 18789892   DOI: 10.1016/j.bbrc.2008.08.167
8785  Yen PH, Kiem PV, Nhiem NX, Tung NH, Quang TH, Minh CV, Kim JW, Choi EM, Kim YH.  A new monoterpene glycoside from the roots of Paeonia lactiflora increases the differentiation of osteoblastic MC3T3-E1 cells.  Arch. Pharm. Res.  2007  30:1179-85  PubMed ID: 18038896   DOI: 10.1007/BF02980258
8803  Kawai S, Yamauchi M, Wakisaka S, Ooshima T, Amano A.  Zinc-finger transcription factor odd-skipped related 2 is one of the regulators in osteoblast proliferation and bone formation.  J. Bone Miner. Res.  2007  22:1362-72  PubMed ID: 17547533   DOI: 10.1359/jbmr.070602
8806  Wang J, Shang F, Jiang R, Liu L, Wang S, Hou J, Huan M, Mei Q.  Nitric oxide-donating genistein prodrug: design, synthesis, and bioactivity on MC3T3-E1 cells.  J. Pharmacol. Sci.  2007  104:82-9  PubMed ID: 17510526   DOI: 10.1254/jphs.fp0061549
8839  J.?E. Raynor, T.?A. Petrie, A.?J. Garcia, D.?M. Collard  Controlling Cell Adhesion to Titanium: Functionalization of Poly[oligo(ethylene glycol)methacrylate] Brushes with Cell-Adhesive Peptides  Adv Mater  2007  19:1724-1728    DOI: 10.1002/adma.200602129
8840  Jiepin Wang, Fujun Shang, Li Liu, Siwang wang, Jianbo Wang, Qibing Mei  In vivo and in vitro activity of genistein in osteoporosis  Indian J Pharmacol   2007  39:103-106   
8841  Ramakrishnaiah Siddappa, Winfried Mulder, Ilse Steeghs, Christine van de Klundert, Jun Liu, Roel Arends, Clemens van Blitterswijk and Jan de Boer  PKA signaling inhibits osteogenic differentiation and bone formation in rodent models  Cellular and Molecular Prerequisites for Bone Tissue Engineering  2007  73-90   
6502  Wako M, Haro H, Ando T, Hatsushika K, Ohba T, Iwabuchi S, Nakao A, Hamada Y.  Novel function of TWEAK in inducing intervertebral disc degeneration.  J Orthop Res  2007  25(11):1438-46  PubMed ID: 17568422   DOI: 10.1002/jor.20445
7055  Tani-Ishii N, Hamada N, Watanabe K, Tujimoto Y, Teranaka T, Umemoto T.  Expression of bone extracellular matrix proteins on osteoblast cells in the presence of mineral trioxide.  J Endod  2007  33(7):836-9  PubMed ID: 17804324   DOI: 10.1016/j.joen.2007.02.003
7057  Arai M, Shibata Y, Pugdee K, Abiko Y, Ogata Y.  Effects of reactive oxygen species (ROS) on antioxidant system and osteoblastic differentiation in MC3T3-E1 cells.  IUBMB Life  2007  59(1):27-33  PubMed ID: 17365177   DOI: 10.1080/15216540601156188
7059  Verlinden L, Vanden Bempt I, Eelen G, Drijkoningen M, Verlinden I, Marchal K, De Wolf-Peeters C, Christiaens MR, Michiels L, Bouillon R, Verstuyf A.  The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor /progesterone receptor /HER-2 breast carcinomas.  Cancer Res  2007  67(14):6574-81  PubMed ID: 17638866   DOI: 10.1158/0008-5472.CAN-06-3545
7061  Lee DH, Lim BS, Lee YK, Yang HC.  Mechanisms of root canal sealers cytotoxicity on osteoblastic cell line MC3T3-E1.  Oral Surg Oral Med Oral Pathol Oral Radiol Endod  2007  104(5):717-21  PubMed ID: 17706441   DOI: 10.1016/j.tripleo.2007.05.018
7064  Choi EM.  Modulatory effects of luteolin on osteoblastic function and inflammatory mediators in osteoblastic MC3T3-E1 cells.  Cell Biol Int  2007  31(9):870-7  PubMed ID: 17368935   DOI: 10.1016/j.cellbi.2007.01.038
7068  Verlinden L, Eelen G, Van Hellemont R, Engelen K, Beullens I, Van Camp M, Marchal K, Mathieu C, Bouillon R, Verstuyf A.  1alpha,25-Dihydroxyvitamin D3-induced down-regulation of the checkpoint proteins, Chk1 and Claspin, is mediated by the pocket proteins p107 and p130.  J Steroid Biochem Mol Biol  2007  103(3-5):411-5  PubMed ID: 17251008   DOI: 10.1016/j.jsbmb.2006.12.080
7070  Kanazawa I, Yamaguchi T, Yano S, Yamauchi M, Yamamoto M, Sugimoto T.  Adiponectin and AMP kinase activator stimulate proliferation, differentiation, and mineralization of osteoblastic MC3T3-E1 cells.  BMC Cell Biol  2007  8:51  PubMed ID: 18047638   DOI: 10.1186/1471-2121-8-51
7071  Choi EM.  Apigenin increases osteoblastic differentiation and inhibits tumor necrosis factor-alpha-induced production of interleukin-6 and nitric oxide in osteoblastic MC3T3-E1 cells.  Pharmazie  2007  62(3):216-20  PubMed ID: 17416199  
7073  Tsubaki M, Kato C, Manno M, Ogaki M, Satou T, Itoh T, Kusunoki T, Tanimori Y, Fujiwara K, Matsuoka H, Nishida S.  Macrophage inflammatory protein-1alpha (MIP-1alpha) enhances a receptor activator of nuclear factor kappaB ligand (RANKL) expression in mouse bone marrow stromal cells and osteoblasts through MAPK and PI3K/Akt pathways.  Mol Cell Biochem  2007  304(1-2):53-60  PubMed ID: 17549607   DOI: 10.1007/s11010-007-9485-7
7076  Murshid SA, Kamioka H, Ishihara Y, Ando R, Sugawara Y, Takano-Yamamoto T.  Actin and microtubule cytoskeletons of the processes of 3D-cultured MC3T3-E1 cells and osteocytes.  J Bone Miner Metab  2007  25(3):151-8  PubMed ID: 17447112   DOI: 10.1007/s00774-006-0745-5
7081  Hata K, Ikebe K, Wada M, Nokubi T.  Osteoblast response to titanium regulates transcriptional activity of Runx2 through MAPK pathway.  J Biomed Mater Res A  2007  81(2):446-52  PubMed ID: 17117476   DOI: 10.1002/jbm.a.31086
7084  Miyazono A, Yamada A, Morimura N, Takami M, Suzuki D, Kobayashi M, Tezuka K, Yamamoto M, Kamijo R.  TGF-beta suppresses POEM expression through ERK1/2 and JNK in osteoblasts.  FEBS Lett  2007  581(27):5321-6  PubMed ID: 17977532   DOI: 10.1016/j.febslet.2007.10.021
7098  Tang CH, Lu DY, Tan TW, Fu WM, Yang RS.  Ultrasound induces hypoxia-inducible factor-1 activation and inducible nitric-oxide synthase expression through the integrin/integrin-linked kinase/Akt/mammalian target of rapamycin pathway in osteoblasts.  J Biol Chem  2007  282(35):25406-15  PubMed ID: 17588951   DOI: 10.1074/jbc.M701001200
7099  Huang Y, Wang Y, Ning C, Nan K, Han Y.  Hydroxyapatite coatings produced on commercially pure titanium by micro-arc oxidation.  Biomed Mater  2007  2(3):196-201  PubMed ID: 18458472   DOI: 10.1088/1748-6041/2/3/005
7110  Sawada N, Taketani Y, Amizuka N, Ichikawa M, Ogawa C, Nomoto K, Nashiki K, Sato T, Arai H, Isshiki M, Segawa H, Yamamoto H, Miyamoto K, Takeda E.  Caveolin-1 in extracellular matrix vesicles secreted from osteoblasts.  Bone  2007  41(1):52-8  PubMed ID: 17448744   DOI: 10.1016/j.bone.2007.02.030
7114  Kono SJ, Oshima Y, Hoshi K, Bonewald LF, Oda H, Nakamura K, Kawaguchi H, Tanaka S.  Erk pathways negatively regulate matrix mineralization.  Bone  2007  40(1):68-74  PubMed ID: 16978937   DOI: 10.1016/j.bone.2006.07.024
7129  Wachiralarpphaithoon C, Iwasaki Y, Akiyoshi K.  Enzyme-degradable phosphorylcholine porous hydrogels cross-linked with polyphosphoesters for cell matrices.  Biomaterials  2007  28(6):984-93  PubMed ID: 17107708   DOI: 10.1016/j.biomaterials.2006.10.024
7169  Simon CG Jr, Stephens JS, Dorsey SM, Becker ML.  Fabrication of combinatorial polymer scaffold libraries.  Rev Sci Instrum  2007  78(7):072207  PubMed ID: 17672738   DOI: 10.1063/1.2755761
7170  Christakos S, Dhawan P, Peng X, Obukhov AG, Nowycky MC, Benn BS, Zhong Y, Liu Y, Shen Q.  New insights into the function and regulation of vitamin D target proteins.  J Steroid Biochem Mol Biol  2007  103(3-5):405-10  PubMed ID: 17257825   DOI: 10.1016/j.jsbmb.2006.12.079
7171  Bandow K, Nishikawa Y, Ohnishi T, Kakimoto K, Soejima K, Iwabuchi S, Kuroe K, Matsuguchi T.  Low-intensity pulsed ultrasound (LIPUS) induces RANKL, MCP-1, and MIP-1beta expression in osteoblasts through the angiotensin II type 1 receptor.  J Cell Physiol  2007  ;211(2):392-8  PubMed ID: 17167786   DOI: 10.1002/jcp.20944
7172  Yu LY, Pei Y, Xia WB, Xing XP, Meng XW, Zhou XY.  Effect of fibroblast growth factor 9 on Runx2 gene promoter activity in MC3T3-E1 and C2C12 cells.  Chin Med J (Engl).   2007  120(6):491-5  PubMed ID: 17439743  
7176  Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu  Investigation on the Biomimetic Scaffold for Bone Tissue Engineering Based on Bioglass-Collagen-Hyaluronic Acid-Phosphatidylserine  Key Engineering Materials  2007  330-332    DOI: 10.4028/
7177  Kino R, Ikoma T, Yunoki S, Nagai N, Tanaka J, Asakura T, Munekata M.  Preparation and characterization of multilayered hydroxyapatite/silk fibroin film.  J Biosci Bioeng  2007  103(6):514-20  PubMed ID: 17630122   DOI: 10.1263/jbb.103.514
7197  Uno K, Takarada T, Hinoi E, Yoneda Y.  Glutamate is a determinant of cellular proliferation through modulation of nuclear factor E2 p45-related factor-2 expression in osteoblastic MC3T3-E1 cells.  J Cell Physiol  2007  213(1):105-14  PubMed ID: 17443688   DOI: 10.1002/jcp.21095
7198  Irwin R, LaPres JJ, Kinser S, McCabe LR.  Prolyl-hydroxylase inhibition and HIF activation in osteoblasts promotes an adipocytic phenotype.  J Cell Biochem  2007  100(3):762-72  PubMed ID: 17031858   DOI: 10.1002/jcb.21083
7199  Maki M, Miyazaki H, Nakajima K, Yamane J, Niisato N, Morihara T, Kubo T, Marunaka Y.  Chloride-dependent acceleration of cell cycle via modulation of Rb and cdc2 in osteoblastic cells.  Biochem Biophys Res Commun  2007  361(4):1038-43  PubMed ID: 17679140   DOI: 10.1016/j.bbrc.2007.07.131
7214  Kawate H, Wu Y, Ohnaka K, Takayanagi R.  Mutual transactivational repression of Runx2 and the androgen receptor by an impairment of their normal compartmentalization.  J Steroid Biochem Mol Biol  2007  105(1-5):46-56  PubMed ID: 17627815   DOI: 10.1016/j.jsbmb.2006.11.020
7227  Ohba S, Nakajima K, Komiyama Y, Kugimiya F, Igawa K, Itaka K, Moro T, Nakamura K, Kawaguchi H, Takato T, Chung UI.  A novel osteogenic helioxanthin-derivative acts in a BMP-dependent manner.  Biochem Biophys Res Commun  2007  357(4):854-60  PubMed ID: 17451649   DOI: 10.1016/j.bbrc.2007.03.173
7232  Ishii T, Wada A, Tsuzuki S, Casolaro M, Ito Y.  Copolymers including L-histidine and hydrophobic moiety for preparation of nonbiofouling surface.  Biomacromolecules  2007  8(11):3340-4  PubMed ID: 17915936   DOI: 10.1021/bm070420h
7234  Kosaku KURATA, Hiroyasu TANIGUCHI, Takanobu FUKUNAGA, Junpei MATSUDA, Hidehiko HIGAKI  Development of a Compact Microbubble Generator and Its Usefulness for Three-Dimensional Osteoblastic Cell Culture  Journal of Biomechanical Science and Engineering  2007  4:166-177    DOI: 10.1299/jbse.2.166
7236  Zhu L, Ye X, Tang G, Zhao N, Gong Y, Zhao Y, Zhao J, Zhang X.  Biomimetic coating of compound titania and hydroxyapatite on titanium.  J Biomed Mater Res A  2007  83(4):1165-75  PubMed ID: 17595022   DOI: 10.1002/jbm.a.31401
7240  Mori K, Le Goff B, Charrier C, Battaglia S, Heymann D, Rédini F.  DU145 human prostate cancer cells express functional receptor activator of NFkappaB: new insights in the prostate cancer bone metastasis process.  Bone  2007  40(4):981-90  PubMed ID: 17196895   DOI: 10.1016/j.bone.2006.11.006
7245  Sawajiri M1, Takinami S, Uchida T, Nomura Y, Mizoe J, Banik S, Tanimoto K.  Expression of MMP-13 in osteoblast cells and rat tibia after exposure to gamma rays or accelerated carbon ions.  Phys Med  2007  23(2):73-9  PubMed ID: 17568546   DOI: 10.1016/j.ejmp.2007.03.005
7246  Maruyama Z, Yoshida CA, Furuichi T, Amizuka N, Ito M, Fukuyama R, Miyazaki T, Kitaura H, Nakamura K, Fujita T, Kanatani N, Moriishi T, Yamana K, Liu W, Kawaguchi H, Nakamura K, Komori T.  Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency.  Dev Dyn  2007  236(7):1876-90  PubMed ID: 17497678   DOI: 10.1002/dvdy.21187
7267  Chau Van Minha , Nguyen Xuan Cuonga , Tran Anh Tuana , Eun Mi Choib , Young Ho Kimb and Phan Van Kiema,  A New 9,11-Secosterol from the Vietnamese Sea Soft Coral, Sarcophyton Mililatensis, Increases the Function of Osteoblastic MC3T3-E1 Cells  Natural Product Communications  2007  2(11)    DOI: 10.1177/1934578X0700201109
7268  Xu HH, Carey LE, Simon CG Jr, Takagi S, Chow LC.  Premixed calcium phosphate cements: synthesis, physical properties, and cell cytotoxicity.  Dent Mater  2007  23(4):433-41  PubMed ID: 16678895   DOI: 10.1016/
7269  Takarada T, Hinoi E, Kambe Y, Sahara K, Kurokawa S, Takahata Y, Yoneda Y.  Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative cytotoxicity of ascorbic acid.  Eur J Pharmacol  2007  575(1-3):1-11  PubMed ID: 17698058   DOI: 10.1016/j.ejphar.2007.07.041
7272  Xu HH, Carey LE, Simon CG Jr.  Premixed macroporous calcium phosphate cement scaffold.  J Mater Sci Mater Med  2007  18(7):1345-53  PubMed ID: 17277972   DOI: 10.1007/s10856-007-0146-x
7276  Zapata P, Su J, García AJ, Meredith JC.  Quantitative high-throughput screening of osteoblast attachment, spreading, and proliferation on demixed polymer blend micropatterns.  Biomacromolecules  2007  8(6):1907-17  PubMed ID: 17506518   DOI: 10.1021/bm061134t
7301  Tadashi Shinohara, Tomoyuki Saito, Daisuke Saito, Makoto Kotani, and Masaaki Aoki  Permanent magnets circuit for collagen orientation  phys stat.sol (c)  2007  4:4333–4336    DOI: 10.1002/pssc.200777290
7335  Sato K, Adachi T, Ueda D, Hojo M, Tomita Y.  Measurement of local strain on cell membrane at initiation point of calcium signaling response to applied mechanical stimulus in osteoblastic cells.  J Biomech  2007  40(6):1246-55  PubMed ID: 16887125   DOI: 10.1016/j.jbiomech.2006.05.028
7336  Miho NAKAMURA, Natalie OHASHI, Akiko NAGAI, Yasutaka SEKIJIMA, Yumi TANAKA, Satoshi NAKAMURA, Kimihiro YAMASHITA  Modulation of Osteoblast-Like Cell Behavior Cultured on Hydroxyapatite by Thrombin  Journal of the Ceramic Society of Japan  2007  115 ;205-209    DOI: 10.2109/jcersj.115.205
7343  Mello A, Hong Z, Rossi AM, Luan L, Farina M, Querido W, Eon J, Terra J, Balasundaram G, Webster T, Feinerman A, Ellis DE, Ketterson JB, Ferreira CL.  Osteoblast proliferation on hydroxyapatite thin coatings produced by right angle magnetron sputtering.  Biomed Mater  2007  2(2):67-77  PubMed ID: 18458438   DOI: 10.1088/1748-6041/2/2/003
7349  Ito M, Haito S, Furumoto M, Uehata Y, Sakurai A, Segawa H, Tatsumi S, Kuwahata M, Miyamoto K.  Unique uptake and efflux systems of inorganic phosphate in osteoclast-like cells.  Am J Physiol Cell Physiol  2007  292(1):C526-34  PubMed ID: 16971494   DOI: 10.1152/ajpcell.00357.2006
7352  Huang MS, Morony S, Lu J, Zhang Z, Bezouglaia O, Tseng W, Tetradis S, Demer LL, Tintut Y.  Atherogenic phospholipids attenuate osteogenic signaling by BMP-2 and parathyroid hormone in osteoblasts.  J Biol Chem  2007  282(29):21237-43  PubMed ID: 17522049   DOI: 10.1074/jbc.M701341200
7356  Hirao M, Hashimoto J, Yamasaki N, Ando W, Tsuboi H, Myoui A, Yoshikawa H.  Oxygen tension is an important mediator of the transformation of osteoblasts to osteocytes.  J Bone Miner Metab  2007  25(5):266-76  PubMed ID: 17704991   DOI: 10.1007/s00774-007-0765-9
7363  Hirata I, Nomura Y, Ito M, Shimazu A, Okazaki M.  Acceleration of bone formation with BMP2 in frame-reinforced carbonate apatite-collagen sponge scaffolds.  J Artif Organs  2007  10(4):212-7  PubMed ID: 18071850   DOI: 10.1007/s10047-007-0391-2
7388  Katsuyama H, Saijoh K, Otsuki T, Tomita M, Fukunaga M, Sunami S.  Menaquinone-7 regulates gene expression in osteoblastic MC3T3E1 cells.  Int J Mol Med  2007  19(2):279-84  PubMed ID: 17203202  
7646  Takao Saito, Hikoshiro Hayashi, Tetsuya Kameyama, Katsuya Kato  Cellular Responses of MC3T3-E1 Mouse Osteoblast-Like Cells to Rough Surfaced Substrates  Key Engineering Materials  2007  361-363:1071-1074    DOI: 10.4028/
7733  Taro Takemura, Toshiyuki Ikoma, Nobutaka Hanagata  Effect of Acid Treated Hydroxyapatite on Osteoblast Maturation  Key Engineering Materials  2007  361-363:1029-1032    DOI: 10.4028/
7856  Miho Nakamura, Akiko Nagai, Natalie Ohashi, Yumi Tanaka, Yasutaka Sekijima, Satoshi Nakamura, Kimihiro Yamashita  Regulation of Osteoblast-Like Cell Behaviors on Hydroxyapatite by Electrical Polarization  Key Engineering Materials   2007  361-363:1055-1058    DOI: 10.4028/
7867  Zhen Hong, Alexandre Mello, Tomohiko Yoshida, Lan Luan, Paula H. Stern, Antonella M. Rossi, Donald E. Ellis, J.B. Ketterson  Increased Osteoblast Proliferation on Hydroxyapatite Thin Coatings Produced by Right Angle Magnetron Sputtering  Key Engineering Materials  2007  361-363:215-218    DOI: 10.4028/
15380  Saita Y, Takagi T, Kitahara K, Usui M, Miyazono K, Ezura Y, Nakashima K, Kurosawa H, Ishii S, Noda M.  Lack of Schnurri-2 expression associates with reduced bone remodeling and osteopenia  J Biol Chem  2007  282(17):12907-1  PubMed ID: 17311925   DOI: 10.1074/jbc.M611203200
14196  Y. Aonuma, T. Adachi, M. Tanaka, M. Hojo, T. Takano-Yamamoto and H. Kamioka  3A1 Cellular & Tissue Engineering & Biomaterials I  A1 Cellular & Tissue Engineering & Biomaterials I  2007  2:S165-S170    DOI: 10.1299/jbse.2.S165
14249  Takafumi Onishi, Toshihiko Shiraishi, Shin Morishita, Ryohei Takeuchi  Viscoelastic Properties of a Cultured Osteoblast Under Adhesive Condition  Biennial Conference on Mechanical Vibration and Noise, Parts A, B, and C  2007  Volume 1: 21st     DOI: 10.1115/detc2007-34944
15461  Zhendong Hong, Alexandre Mello, Tomohiko Yoshida, Lan Luan, Paula H. Stern, Alexandre Rossi, Donald E. Ellis, John B. Ketterson  Hydroxyapatite Coatings Produced by Right Angle Magnetron Sputtering for Biomedical Applications  MRS Proceedings  2007  1008    DOI: 10.1557/proc-1008-t10-04
17400  Tetsuo Shikata, Toshihiko Shiraishi, Kumiko Tanaka, Shin Morishita, Ryohei Takeuchi  Effects of Acceleration Amplitude and Frequency of Mechanical Vibration on Osteoblast-Like Cells  Biomedical and Biotechnology Engineering  2007  2    DOI: 10.1115/imece2007-41797
17401  Yokoi T, Saito M, Kiyono T, Iseki S, Kosaka K, Nishida E, Tsubakimoto T, Harada H, Eto K, Noguchi T, Teranaka T.  Establishment of immortalized dental follicle cells for generating periodontal ligament in vivo  Cell Tissue Res  2007  327(2):301-11  PubMed ID: 17013589   DOI: 10.1007/s00441-006-0257-6
17402  Hacchou Y, Uematsu T, Ueda O, Usui Y, Uematsu S, Takahashi M, Uchihashi T, Kawazoe Y, Shiba T, Kurihara S, Yamaoka M, Furusawa K.  Inorganic polyphosphate: a possible stimulant of bone formation  J Dent Res  2007  86(9):893-7  PubMed ID: 17720862   DOI: 10.1177/154405910708600917
3405  Ozeki K, Aoki H, Fukui Y  Dissolution behavior and in vitro evaluation of sputtered hydroxyapatite films subject to a low temperature hydrothermal treatment.  J Biomed Mater Res A  2006  76:605-13  PubMed ID: 16278871   DOI: 10.1002/jbm.a.30574
3398  Ouyang, Xinshou, Fujimoto, Minoru, Nakagawa, Reiko, Serada, Satoshi, Tanaka, Toshio, Nomura, Shintaro, Kawase, Ichiro, Kishimoto, Tadamitsu, Naka, Tetsuji  SOCS-2 interferes with myotube formation and potentiates osteoblast differentiation through upregulation of JunB in C2C12 cells.  J Cell Physiol  2006  207:428-36  PubMed ID: 16419040   DOI: 10.1002/jcp.20579
8879  Hanagata N, Takemura T, Monkawa A, Ikoma T, Tanaka J.  Pre-adsorbed type-I collagen structure-dependent changes in osteoblastic phenotype.  Biochem. Biophys. Res. Commun.  2006  344:1234-40  PubMed ID: 16647688   DOI: 10.1016/j.bbrc.2006.04.021
6487  Hinoi E, Ueshima T, Hojo H, Iemata M, Takarada T, Yoneda Y.  Up-regulation of per mRNA expression by parathyroid hormone through a protein kinase A-CREB-dependent mechanism in chondrocytes.  J Biol Chem  2006  281(33):23632-42  PubMed ID: 16777848   DOI: 10.1074/jbc.M512362200
6489  Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A.  TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.  Arthritis Res Ther  2006  8(5):R146  PubMed ID: 16945157   DOI: 10.1186/ar2038
6971  Lee DH, Park BJ, Lee MS, Lee JW, Kim JK, Yang HC, Park JC.  Chemotactic migration of human mesenchymal stem cells and MC3T3-E1 osteoblast-like cells induced by COS-7 cell line expressing rhBMP-7.  Tissue Eng  2006  12(6):1577-86  PubMed ID: 16846353   DOI: 10.1089/ten.2006.12.1577
6972  Lee KH, Choi EM.  Rubus coreanus Miq. extract promotes osteoblast differentiation and inhibits bone-resorbing mediators in MC3T3-E1 cells.  Am J Chin Med  2006  34(4):643-54.  PubMed ID: 16883635   DOI: 10.1142/S0192415X0600417X
6973  Li J, Yun H, Gong Y, Zhao N, Zhang X.  Investigation of MC3T3-E1 cell behavior on the surface of GRGDS-coupled chitosan.  Biomacromolecules  2006  7(4):1112-23  PubMed ID: 16602728   DOI: 10.1021/bm050913r
6974  Yoshida T, Asanuma M, Grossmann L, Fuse M, Shibata T, Yonekawa T, Tanaka T, Ueno K, Yasuda T, Saito Y, Tatsuno I.  Geranylgeranyl-pyrophosphate (GGPP) synthase is down-regulated during differentiation of osteoblastic cell line MC3T3-E1.  FEBS Lett  2006  580(22):5203-7  PubMed ID: 16978613   DOI: 10.1016/j.febslet.2006.08.060
6975  Sawajiri M, Nomura Y, Bhawal UK, Nishikiori R, Okazaki M, Mizoe J, Tanimoto K.  Different effects of carbon ion and gamma-irradiation on expression of receptor activator of NF-kB ligand in MC3T3-E1 osteoblast cells.  Bull Exp Biol Med  2006  142(5):618-24  PubMed ID: 17415477   DOI: 10.1007/s10517-006-0433-4
6976  Nagai N, Anzawa T, Satoh Y, Suzuki T, Tajima K, Munekata M.  Activities of MC3T3-E1 cells cultured on gamma-irradiated salmon atelocollagen scaffold.  J Biosci Bioeng  2006  101(6):511-4  PubMed ID: 16935254   DOI: 10.1263/jbb.101.511
7051  Lee KH, Choi EM.  Stimulatory effects of extract prepared from the bark of Cinnamomum cassia blume on the function of osteoblastic MC3T3-E1 cells.  Phytother Res  2006  20(11):952-60  PubMed ID: 16906639   DOI: 10.1002/ptr.1984
6977  Hori M, Sawai H, Tsuji Y, Okamura H, Koyama K.  Bone morphogenetic protein-2 counterregulates interleukin-18 mRNA and protein in MC3T3-E1 mouse osteoblastic cells.  Connect Tissue Res  2006  47(3):124-32  PubMed ID: 16753805   DOI: 10.1080/03008200600685350
6978  Lee DH, Lim BS, Lee YK, Yang HC.  Effects of hydrogen peroxide (H2O2) on alkaline phosphatase activity and matrix mineralization of odontoblast and osteoblast cell lines.  Cell Biol Toxicol  2006  22(1):39-46  PubMed ID: 16463018   DOI: 10.1007/s10565-006-0018-z
6979  Kaneko, M. et al  Synthesis and characterization of calcium phosphate-AMP layered materials  Key Engineering Materials  2006  317-318:769-772    DOI: 10.4028/
6980  Tachibana A, Nishikawa Y, Nishino M, Kaneko S, Tanabe T, Yamauchi K.  Modified keratin sponge: binding of bone morphogenetic protein-2 and osteoblast differentiation.  J Biosci Bioeng  2006  102(5):425-9  PubMed ID: 17189169   DOI: 10.1263/jbb.102.425
6981  Narita Y, Nomura J, Ohta S, Inoh Y, Suzuki KM, Araki Y, Okada S, Matsumoto I, Isohama Y, Abe K, Miyata T, Mishima S.  Royal jelly stimulates bone formation: physiologic and nutrigenomic studies with mice and cell lines.  Biosci Biotechnol Biochem  2006  70(10):2508-14  PubMed ID: 17031045   DOI: 10.1271/bbb.60240
6982  Petrie TA, Capadona JR, Reyes CD, García AJ.  Integrin specificity and enhanced cellular activities associated with surfaces presenting a recombinant fibronectin fragment compared to RGD supports.  Biomaterials  2006  27(31):5459-70  PubMed ID: 16846640   DOI: 10.1016/j.biomaterials.2006.06.027
6983  Gao Y, Cao WL, Wang XY, Gong YD, Tian JM, Zhao NM, Zhang XF.  Characterization and osteoblast-like cell compatibility of porous scaffolds: bovine hydroxyapatite and novel hydroxyapatite artificial bone.  J Mater Sci Mater Med  2006  17(9):815-23  PubMed ID: 16932863   DOI: 10.1007/s10856-006-9840-3
6985  Teraoka F, Nakagawa M, Hara M.  Surface modification of poly (L-lactide) by atmospheric pressure plasma treatment and cell response.  Dent Mater J  2006  25(3):560-5  PubMed ID: 17076328   DOI: 10.4012/dmj.25.560
6986  Kennedy SB, Washburn NR, Simon CG Jr, Amis EJ.  Combinatorial screen of the effect of surface energy on fibronectin-mediated osteoblast adhesion, spreading and proliferation.  Biomaterials  2006  27(20):3817-24  PubMed ID: 16563495   DOI: 10.1016/j.biomaterials.2006.02.044
6987  Takafumi ONISHI, Toshihiko SHIRASHI, Shin MORISHITA  Mechanical properties of a cultured osteoblast  Journal of Advanced Science  2006  18:95-98    DOI: 10.2978/jsas.18.95
6988  Hinoi E, Fujimori S, Wang L, Hojo H, Uno K, Yoneda Y.  Nrf2 negatively regulates osteoblast differentiation via interfering with Runx2-dependent transcriptional activation.  J Biol Chem  2006  281(26):18015-24  PubMed ID: 16613847   DOI: 10.1074/jbc.M600603200
6989  Yingjun Wang Chunrong Yang Xiaofeng Chen Naru Zhao  Development and Characterization of Novel Biomimetic Composite Scaffolds Based on Bioglass‐Collagen‐Hyaluronic Acid‐Phosphatidylserine for Tissue Engineering Applications  Macromol Mater Eng  2006  291:254–262    DOI: 10.1002/mame.200500381
6990  Han DW, Park HK, Park YH, Kim TS, Yoon WS, Kim JK, Park JC.  Beneficial effects of freezing rate determined by indirect thermophysical calculation on cell viability in cryopreserved tissues.  Artif Cells Blood Substit Immobil Biotechnol  2006  34(2):205-21  PubMed ID: 16537175   DOI: 10.1080/10731190600581742
6991  Boilard E, Rouault M, Surrel F, Le Calvez C, Bezzine S, Singer A, Gelb MH, Lambeau G.  Secreted phospholipase A2 inhibitors are also potent blockers of binding to the M-type receptor.  Biochemistry  2006  45(44):13203-18  PubMed ID: 17073442   DOI: 10.1021/bi061376d
6993  Nakashima A, Tamura M.  Regulation of matrix metalloproteinase-13 and tissue inhibitor of matrix metalloproteinase-1 gene expression by WNT3A and bone morphogenetic protein-2 in osteoblastic differentiation.  Front Biosci  2006  11:1667-78  PubMed ID: 16368545   DOI: 10.2741/1912
6994  Hosaka M, Shibata Y, Miyazaki T.  Preliminary beta-tricalcium phosphate coating prepared by discharging in a modified body fluid enhances collagen immobilization onto titanium.  J Biomed Mater Res B Appl Biomater  2006  78(2):237-42  PubMed ID: 16362961   DOI: 10.1002/jbm.b.30478
6995  M. Iwasakaa and T. Kurakane  Magnetic cell manipulation utilizing magnetic particles and diamagnetic collagen fibers  Journal of Applied Physics  2006  99: 08R90    DOI: 10.1063/1.2175957
6996  Yokota R, Hayashi H, Hirata I, Miake Y, Yanagisawa T, Okazaki M.  Detailed consideration of physicochemical properties of CO3apatites as biomaterials in relation to carbonate content using ICP, X-ray diffraction, FT-IR, SEM, and HR-TEM.  Dent Mater J  2006  25(3):597-603  PubMed ID: 17076333   DOI: 10.4012/dmj.25.597
6997  Sugama R, Koike T, Imai Y, Nomura-Furuwatari C, Takaoka K.  Bone morphogenetic protein activities are enhanced by 3',5'-cyclic adenosine monophosphate through suppression of Smad6 expression in osteoprogenitor cells.  Bone  2006  38(2):206-14  PubMed ID: 16203197   DOI: 10.1016/j.bone.2005.08.006
6998  Kawai S, Kato T, Sato M, Amano A.  Odd-skipped related 2 gene transcription is regulated by CCAAT enhancer-binding protein delta in mesenchymal C3H10T1/2 cells.  Genes Cells  2006  11(2):163-75  PubMed ID: 16436053   DOI: 10.1111/j.1365-2443.2006.00929.x
6999  Hajime SHINOHARA, Hikaru TAKEI, Daisuke SAITO, Makoto KOTANI, Shogo UENO, Atsushi NAKAHIRA  Fundamental Study on Bone Formation Using Collagen Orientation Induced by Magnetic Fields  Journal of the Ceramic Society of Japan  2006  114:131-134    DOI: 10.2109/jcersj.114.131
7007  Katsuya SATO, Taiji ADACHI, Yasuhito SHIRAI, Naoaki SAITO, Yoshihiro TOMITA  Local Disassembly of Actin Stress Fibers Induced by Selected Release of Intracellular Tension in Osteoblastic Cell  Journal of Biomechanical Science and Engineering  2006  1:204-214    DOI: 10.1299/jbse.1.204
15421  Hinoi E, Takarada T, Tsuchihashi Y, Fujimori S, Moriguchi N, Wang L, Uno K, Yoneda Y.  A molecular mechanism of pyruvate protection against cytotoxicity of reactive oxygen species in osteoblasts  Mol Pharmacol5  2006  70(3):925-3  PubMed ID: 16766717   DOI: 10.1124/mol.106.024398
15422  Casolaro M, Casolaro I, Spreafico A, Capperucci C, Frediani B, Marcolongo R, Margiotta N, Ostuni R, Mendichi R, Samperi F, Ishii T, Ito Y.  Novel therapeutic agents for bone resorption. Part 1. Synthesis and protonation thermodynamics of poly(amido-amine)s containing bis-phosphonate residues  Biomacromolecules  2006  7(12):3417-27  PubMed ID: 17154470   DOI: 10.1021/bm0607630
15423  T. ADACHI, K. SATO  THRESHOLD FIBER STRAIN THAT INDUCES REORGANIZATION OF CYTOSKELETAL ACTIN STRUCTURE IN OSTEOBLASTIC CELLS  Biomechanics at Micro- and Nanoscale Levels  2006  51-61    DOI: 10.1142/9789812773838_0005
15424  M. Okazaki, Y. Tieliewuhan, I. Hirata  Osteoblast Behavior at the Surface of CO3Ap-Collagen Sponges  Key Engineering Materials  2006  989-992    DOI: 10.4028/
5572  Tang CH, Yang RS, Huang TH, Lu DY, Chuang WJ, Huang TF, Fu WM.  Ultrasound stimulates cyclooxygenase-2 expression and increases bone formation through integrin, focal adhesion kinase, phosphatidylinositol 3-kinase, and Akt pathway in osteoblasts  Mol Pharmacol  2006  69(6):2047-57  PubMed ID: 16540596   DOI: 10.1124/mol.105.022160
3348  Motokawa M, Kaku M, Tohma Y, Kawata T, Fujita T, Kohno S, Tsutsui K, Ohtani J, Tenjo K, Shigekawa M, Kamada H, Tanne K  Effects of cyclic tensile forces on the expression of vascular endothelial growth factor (VEGF) and macrophage-colony-stimulating factor (M-CSF) in murine osteoblastic MC3T3-E1 cells.  J Dent Res  2005  84:422-7  PubMed ID: 15840777   DOI: 10.1177/154405910508400505
2897  Kim SW, Her SJ, Kim SY, Shin CS  Ectopic overexpression of adipogenic transcription factors induces transdifferentiation of MC3T3-E1 osteoblasts.  Biochem Biophys Res Commun  2005  327:811-9  PubMed ID: 15649418   DOI: 10.1016/j.bbrc.2004.12.076
2915  Nobta M, Tsukazaki T, Shibata Y, Xin C, Moriishi T, Sakano S, Shindo H, Yamaguchi A  Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling.  J Biol Chem  2005  280:15842-8  PubMed ID: 15695512   DOI: 10.1074/jbc.M412891200
3018  Sato K, Adachi T, Matsuo M, Tomita Y  Quantitative evaluation of threshold fiber strain that induces reorganization of cytoskeletal actin fiber structure in osteoblastic cells.  J Biomech  2005  38:1895-901  PubMed ID: 16023478   DOI: 10.1016/j.jbiomech.2004.08.012
3069  Inoue H, Nishimura K, Oka D, Nakai Y, Shiba M, Tokizane T, Arai Y, Nakayama M, Shimizu K, Takaha N, Nonomura N, Okuyama A  Prostate cancer mediates osteoclastogenesis through two different pathways.  Cancer Lett  2005  223:121-8  PubMed ID: 15890244   DOI: 10.1016/j.canlet.2004.09.053
3084  Kawate H, Wu Y, Ohnaka K, Nawata H, Takayanagi R  Tob proteins suppress steroid hormone receptor-mediated transcriptional activation.  Mol Cell Endocrinol  2005  230:77-86  PubMed ID: 15664454   DOI: 10.1016/j.mce.2004.10.009
3407  Ito, Mikiko, Sakai, Yuko, Furumoto, Mari, Segawa, Hiroko, Haito, Sakiko, Yamanaka, Setsuko, Nakamura, Rie, Kuwahata, Masashi, Miyamoto, Ken-ichi  Vitamin D and phosphate regulate fibroblast growth factor-23 in K-562 cells.  Am J Physiol Endocrinol Metab  2005  288:E1101-9  PubMed ID: 15671080   DOI: 10.1152/ajpendo.00502.2004
2930  Keselowsky, Benjamin G, Collard, David M, Garcia, Andres J  Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation.  Proc Natl Acad Sci U S A  2005  102:5953-7  PubMed ID: 15827122   DOI: 10.1073/pnas.0407356102
8952  Lee KH, Choi EM.  Biochanin A stimulates osteoblastic differentiation and inhibits hydrogen peroxide-induced production of inflammatory mediators in MC3T3-E1 cells.  Biol. Pharm. Bull.  2005  28:1948-53  PubMed ID: 16204952   DOI: 10.1248/bpb.28.1948
9012  Choi EM.  The licorice root derived isoflavan glabridin increases the function of osteoblastic MC3T3-E1 cells.  Biochem. Pharmacol.  2005  70:363-8  PubMed ID: 15922308   DOI: 10.1016/j.bcp.2005.04.019
6283  Nagasawa H, Takahashi S, Kobayashi A, Tazawa H, Tashima Y, Sato K.  Effect of retinoic acid on murine preosteoblastic MC3T3-E1 cells.  J Nutr Sci Vitaminol (Tokyo)  2005  51(5):311-8  PubMed ID: 16392701   DOI: 10.3177/jnsv.51.311
4968  Okada A, Shiomi T, Aoki Y, Fujiwara M.  Phenytoin stimulates chondrogenic differentiation in mouse clonal chondrogenic EC cells, ATDC5.  J Toxicol Sci  2005  30(3):145-56  PubMed ID: 16141649   DOI: 10.2131/jts.30.145
6824  Kim SW, Her SJ, Park SJ, Kim D, Park KS, Lee HK, Han BH, Kim MS, Shin CS, Kim SY.  Ghrelin stimulates proliferation and differentiation and inhibits apoptosis in osteoblastic MC3T3-E1 cells.  Bone  2005  37(3):359-69  PubMed ID: 15978880   DOI: 10.1016/j.bone.2005.04.020
6825  Li J, Yun H, Gong Y, Zhao N, Zhang X.  Effects of surface modification of poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) on physicochemical properties and on interactions with MC3T3-E1 cells.  J Biomed Mater Res A  2005  75(4):985-98  PubMed ID: 16134174   DOI: 10.1002/jbm.a.30504
6826  Xi J, Kong L, Gao Y, Gong Y, Zhao N, Zhang X.  Properties of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) films modified with polyvinylpyrrolidone and behavior of MC3T3-E1 osteoblasts cultured on the blended films.  J Biomater Sci Polym Ed  2005  16(11):1395-408  PubMed ID: 16370240   DOI: 10.1163/156856205774472344
6827  Takashi M, Tsubaki S, Tsuzuki T, Duarte WR, Yamauchi M, Sato H.  Differential gene expression of collagen-binding small leucine-rich proteoglycans and lysyl hydroxylases, during mineralization by MC3T3-E1 cells cultured on titanium implant material.  Eur J Oral Sci  2005  113(3):225-31  PubMed ID: 15953247   DOI: 10.1111/j.1600-0722.2005.00208.x
6829  D.H. Lee, Dong Wook Han, B.J. Park, Hyun Sook Baek, K. Takatori, M. Aihara, Kazufumi Tsubaki, Jong Chul Park  The Influences of β-Glucan Associated with BMP-7 on MC3T3-E1 Proliferation and Osteogenic Differentiation  Key Engineering Materials  2005  288-289:241-244    DOI: 10.4028/
6830  Yoko Otsuka-Tanaka, Toshinori Sato, Tomohisa Fujita, Hiroshi Suzuki, Misao Kawara, Yoshimitsu Abiko, Junichi Mega  Reduction of Bone Nodule Formation in MC3T3-E1 Cells by Treatment with Hydrogen Peroxide  International Journal of Oral-Medical Sciences  2005  4:97-102    DOI: 10.5466/ijoms.4.97
6836  Kikuji Yamashita, Jun Ishibashi, Hiroyoshi Hosokawa, Nanami Ishikawa, Hiroyuki Morimoto, Tomoyasu Ishikawa, Masaru Nagayama, Seiichiro Kitamura  Microarray Analysis of Gene Expression in MC3T3-E1 after Specific Far-infrared Radiation  Journal of Hard Tissue Biology  2005  14:206-207    DOI: 10.2485/jhtb.14.206
6838  Ku Y, Chung CP, Jang JH.  The effect of the surface modification of titanium using a recombinant fragment of fibronectin and vitronectin on cell behavior.  Biomaterials  2005  26(25):5153-7  PubMed ID: 15792542   DOI: 10.1016/j.biomaterials.2005.01.060
6839  Keselowsky BG, García AJ.  Quantitative methods for analysis of integrin binding and focal adhesion formation on biomaterial surfaces.  Biomaterials  2005  26(4):413-8  PubMed ID: 15275815   DOI: 10.1016/j.biomaterials.2004.02.050
6840  Yang RS, Lin WL, Chen YZ, Tang CH, Huang TH, Lu BY, Fu WM.  Regulation by ultrasound treatment on the integrin expression and differentiation of osteoblasts.  Bone  2005  36(2):276-83  PubMed ID: 15780953   DOI: 10.1016/j.bone.2004.10.009
6841  Kazuo Isama, Toshie Tsuchiya  Osteoblast differentiation and apatite formation on gamma-irradiated PLLA sheets  Key Engineering Materials   2005  288-289:409-412    DOI: 10.4028/
6842  Tachibana A, Kaneko S, Tanabe T, Yamauchi K.  Rapid fabrication of keratin-hydroxyapatite hybrid sponges toward osteoblast cultivation and differentiation.  Biomaterials  2005  26(3):297-302  PubMed ID: 15262471   DOI: 10.1016/j.biomaterials.2004.02.032
6843  Dong HeeLee, Hyun Sook Baek, Mi Hee Lee, Jong-Chul Parka  Production of bone morphogenetic protein-7 using pET expression system  Current Applied Physics  2005  5:422-425    DOI: 10.1016/j.cap.2005.01.003
6844  Zhang K, Washburn NR, Simon CG Jr.  Cytotoxicity of three-dimensionally ordered macroporous sol-gel bioactive glass (3DOM-BG).  Biomaterials  2005  26(22):4532-9  PubMed ID: 15722122   DOI: 10.1016/j.biomaterials.2004.11.030
6845  Kai Zhang, Newell R. Washburn, Joseph M. Antonucci, Carl G. Simon  In Vitro Culture of Osteoblasts with Three Dimensionally Ordered Macroporous Sol-Gel Bioactive Glass (3DOM-BG) Particles  Key Engineering Materials  2005  284-286:655-658    DOI: 10.4028/
6846  Jing Li Yandao Gong Nanming Zhao Xiufang Zhang  Preparation of N‐butyl chitosan and study of its physical and biological properties  Journal of applied polymer science  2005  98:1016-1024    DOI: 10.1002/app.22212
6847  J. R. Capadona T. A. Petrie K. P. Fears R. A. Latour D. M. Collard A. J. García  Surface‐Nucleated Assembly of Fibrillar Extracellular Matrices  Adv Mater  2005  17:2604–2608    DOI: 10.1002/adma.200500959
6848  C. G. Simon, Jr, J. M. Antonucci, D. W. Liu, D. Skrtic D. Skrtic  In vitro Cytotoxicity of Amorphous Calcium Phosphate Composites  Journal of Bioactive and Compatible Polymers  2005  20:279-295    DOI: 10.1177/0883911505051854
6849  Verlinden L, Eelen G, Beullens I, Van Camp M, Van Hummelen P, Engelen K, Van Hellemont R, Marchal K, De Moor B, Foijer F, Te Riele H, Beullens M, Bollen M, Mathieu C, Bouillon R, Verstuyf A.  Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.  J Biol Chem  2005  280(45):37319-30  PubMed ID: 16144839   DOI: 10.1074/jbc.M503587200
6850  Shen Q1, Christakos S.  The vitamin D receptor, Runx2, and the Notch signaling pathway cooperate in the transcriptional regulation of osteopontin.  J Biol Chem  2005  280(49):40589-98  PubMed ID: 16195230   DOI: 10.1074/jbc.M504166200
6851  Susumu Hamajima, Toshinori Sato, Yoko-Otsuka Tanaka, Chia-Hua Yang, Nobuyuki Watanabe, Junichi Mega, Toshiro Sakae, Yoshimitsu Abiko  Identification of Reduced Fibronectin 1 Gene Expression in Osteoblasts following Hydrogen Peroxide Treatment using Subtractive Gene Cloning  Journal of Hard Tissue Biology  2005  14:32-37    DOI: 10.2485/jhtb.14.32
6852  K. Ozeki, Hideyuki Aoki, Y. Fukui  Crystallization of sputtered hydroxyapatite films by hydrothermal technique and its cytotoxicity  Key Engineering Materials  2005  284-286:195-198    DOI: 10.4028/
6853  Ohta H, Wakitani S, Tensho K, Horiuchi H, Wakabayashi S, Saito N, Nakamura Y, Nozaki K, Imai Y, Takaoka K.  The effects of heat on the biological activity of recombinant human bone morphogenetic protein-2.  J Bone Miner Metab  2005  23(6):420-5  PubMed ID: 16261447   DOI: 10.1007/s00774-005-0623-6
6854  Simon CG Jr, Eidelman N, Kennedy SB, Sehgal A, Khatri CA, Washburn NR.  Combinatorial screening of cell proliferation on poly(L-lactic acid)/poly(D,L-lactic acid) blends.  Biomaterials  2005  26(34):6906-15  PubMed ID: 15939467   DOI: 10.1016/j.biomaterials.2005.04.050
6855  Zhang K, Simon CG Jr, Washburn NR, Antonucci JM, Lin-Gibson S.  In situ formation of blends by photopolymerization of poly(ethylene glycol) dimethacrylate and polylactide.  Biomacromolecules.  2005  6(3):1615-22  PubMed ID: 15877385   DOI: 10.1021/bm0500648
6856  Xu HH1, Simon CG Jr.  Fast setting calcium phosphate-chitosan scaffold: mechanical properties and biocompatibility.  Biomaterials  2005  26(12):1337-48  PubMed ID: 15482821   DOI: 10.1016/j.biomaterials.2004.04.043
6857  Liu Y, Shen Q, Malloy PJ, Soliman E, Peng X, Kim S, Pike JW, Feldman D, Christakos S.  Enhanced coactivator binding and transcriptional activation of mutant vitamin D receptors from patients with hereditary 1,25-dihydroxyvitamin D-resistant rickets by phosphorylation and vitamin D analogs.  J Bone Miner Res  2005  20(9):1680-91  PubMed ID: 16059639   DOI: 10.1359/JBMR.050410
6858  Yo Shibata, Takashi Miyazaki  Antibacterial titanium plate anodized by discharging in NaCl solution exhibits cell compatibility  International Congress Series  2005  1284:284-289    DOI: 10.1016/j.ics.2005.07.064
6859  Nakamura Y, Wakitani S, Saito N, Takaoka K.  Expression profiles of BMP-related molecules induced by BMP-2 or -4 in muscle-derived primary culture cells.  J Bone Miner Metab  2005  23(6):426-34  PubMed ID: 16261448   DOI: 10.1007/s00774-005-0624-5
6860  Oshima T, Abe M, Asano J, Hara T, Kitazoe K, Sekimoto E, Tanaka Y, Shibata H, Hashimoto T, Ozaki S, Kido S, Inoue D, Matsumoto T.  Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2.  Blood  2005  106(9):3160-5  PubMed ID: 16030194   DOI: 10.1182/blood-2004-12-4940
6861  Kimura T, Sato Y, Kimura F, Iwasaka M, Ueno S.  Micropatterning of cells using modulated magnetic fields.  Langmuir  2005  21(3):830-2  PubMed ID: 15667156   DOI: 10.1021/la047517z
6863  Carey LE, Xu HH, Simon CG Jr, Takagi S, Chow LC.  Premixed rapid-setting calcium phosphate composites for bone repair.  Biomaterials.  2005  26(24):5002-14  PubMed ID: 15769536   DOI: 10.1016/j.biomaterials.2005.01.015
6864  Sakuma-Zenke M, Sakai A, Nakayamada S, Kunugita N, Tabata T, Uchida S, Tanaka S, Mori T, Nakai K, Tanaka Y, Nakamura T.  Reduced expression of platelet endothelial cell adhesion molecule-1 in bone marrow cells in mice after skeletal unloading.  J Bone Miner Res  2005  20(6):1002-10  PubMed ID: 15883641   DOI: 10.1359/JBMR.050102
6865  Tamada Y.  New process to form a silk fibroin porous 3-D structure.  Biomacromolecules  2005  6(6):3100-6  PubMed ID: 16283733   DOI: 10.1021/bm050431f
6867  Hirata I, Nomura Y, Tabata H, Miake Y, Yanagisawa T, Okazaki M.  SEM observation of collagen fibrils secreted from the body surface of osteoblasts on a CO3apatite-collagen sponge.  Dent Mater J  2005  24(3):460-4  PubMed ID: 16279740   DOI: 10.4012/dmj.24.460
8188  Lieve Verlinden, Guy Eelen, Ine Beullens, Mark Van Camp, Paul Van Hummelen, Kristof Engelen, Ruth Van Hellemont, Kathleen Marchal, Bart De Moor, Floris Foijer  Characterization of the Condensin Component Cnap1 and Protein Kinase Melk as Novel E2F Target Genes Downregulated by 1,25-Dihydroxyvitamin D3  JOURNAL OF BIOLOGICAL CHEMISTRY  2005  280:37319 –37330   
15418  Jing Xi, Yuan Gao, Lijun Kong, Yandao Gong, Nanming Zhao, Xiufang Zhang  Behavior of MC3T3-El osteoblast cultured on chitosan modified with polyvinylpyrrolidone  Tsinghua Science and Technology  2005  10:339-444    DOI: 10.1016/s1007-0214(05)70097-3
15420  M. Kumaoka, T. Shiraishi, S. Morishita  Effects of Mechanical Vibration on Osteoblast-Like Cell Line  Advances in Bioengineering  2005      DOI: 10.1115/imece2005-81980
5569  Katsuyama H, Otsuki T, Tomita M, Fukunaga M, Fukunaga T, Suzuki N, Saijoh K, Fushimi S, Sunami S.  Menaquinone-7 regulates the expressions of osteocalcin, OPG, RANKL and RANK in osteoblastic MC3T3E1 cells  Int J Mol Med  2005  15(2):231-6  PubMed ID: 15647836  
3158  Nishimura, Haruki, Nishimura, Masahiro, Oda, Ryo, Yamanaka, Katsuyuki, Matsubara, Takehiro, Ozaki, Yoshie, Sekiya, Kensuke, Hamada, Taizo, Kato, Yukio  Lectins induce resistance to proteases and/or mechanical stimulus in all examined cells--including bone marrow mesenchymal stem cells--on various scaffolds.  Exp Cell Res  2004  295:119-27  PubMed ID: 15051495   DOI: 10.1016/j.yexcr.2003.12.018
2726  Inoue M, LeGeros RZ, Inoue M, Tsujigiwa H, Nagatsuka H, Yamamoto T, Nagai N  In vitro response of osteoblast-like and odontoblast-like cells to unsubstituted and substituted apatites  J Biomed Mater Res  2004  70A:585-593  PubMed ID: 15307163   DOI: 10.1002/jbm.a.30116
2870  Fukuyama R, Fujita T, Azuma Y, Hirano A, Nakamuta H, Koida M, Komori T  Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling.  Biochem Biophys Res Commun  2004  315:636-42  PubMed ID: 14975748   DOI: 10.1016/j.bbrc.2004.01.104
2871  Notoya M, Otsuka E, Yamaguchi A, Hagiwara H  Runx-2 is not essential for the vitamin D-regulated expression of RANKL and osteoprotegerin in osteoblastic cells.  Biochem Biophys Res Commun  2004  324:655-60  PubMed ID: 15474477   DOI: 10.1016/j.bbrc.2004.09.101
3051  Mogi M, Ozeki N, Nakamura H, Togari A  Dual roles for NF-kappaB activation in osteoblastic cells by serum deprivation: osteoblastic apoptosis and cell-cycle arrest.  Bone  2004  35:507-16  PubMed ID: 15268903   DOI: 10.1016/j.bone.2004.03.003
2822  Zhang, Gui Xia, Mizuno, Morimichi, Tsuji, Kiyomi, Tamura, Masato  Regulation of mRNA expression of matrix extracellular phosphoglycoprotein (MEPE)/ osteoblast/osteocyte factor 45 (OF45) by fibroblast growth factor 2 in cultures of rat bone marrow-derived osteoblastic cells.  Endocrine  2004  24:15-24  PubMed ID: 15249699   DOI: 10.1385/ENDO:24:1:015
2926  French, Dorothy M, Kaul, Raji J, D'Souza, Aloma L, Crowley, Craig W, Bao, Min, Frantz, Gretchen D, Filvaroff, Ellen H, Desnoyers, Luc  WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair.  Am J Pathol  2004  165:855-67  PubMed ID: 15331410   DOI: 10.1016/S0002-9440(10)63348-2
3096  Sogo Y. et al.  Zinc containing hydroxyapatite ceramics to promote osteoblastic cell activity.  Materials Schience and Technology  2004  20:1079-1083    DOI: 10.1179/026708304225019704
5415  Saito M, Soshi S, Tanaka T, Fujii K.  Intensity-related differences in collagen post-translational modification in MC3T3-E1 osteoblasts after exposure to low- and high-intensity pulsed ultrasound.  Bone  2004  35(3):644-55  PubMed ID: 15336600   DOI: 10.1016/j.bone.2004.04.024
6711  J Steroid Biochem Mol Biol  Microarray analysis of 1alpha,25-dihydroxyvitamin D3-treated MC3T3-E1 cells.  Eelen G, Verlinden L, Van Camp M, Mathieu C, Carmeliet G, Bouillon R, Verstuyf A.  2004  89-90(1-5):405-7.  PubMed ID: 15225810   DOI: 10.1016/j.jsbmb.2004.03.008
6712  Kanno S, Hirano S, Kayama F.  Effects of phytoestrogens and environmental estrogens on osteoblastic differentiation in MC3T3-E1 cells.  Toxicology  2004  196(1-2):137-45  PubMed ID: 15036763   DOI: 10.1016/j.tox.2003.12.002
6713    Effect of low- and high-intensity pulsed ultrasound on collagen post-translational modifications in MC3T3-E1 osteoblasts.  Calcif Tissue Int  2004  75(5):384-95. Epub 2004 Jul 13  PubMed ID: 15592795   DOI: 10.1007/s00223-004-0292-9
6714  Date T, Doiguchi Y, Nobuta M, Shindo H.  Bone morphogenetic protein-2 induces differentiation of multipotent C3H10T1/2 cells into osteoblasts, chondrocytes, and adipocytes in vivo and in vitro.  J Orthop Sci  2004  9(5):503-8  PubMed ID: 15449126   DOI: 10.1007/s00776-004-0815-2
6715  Hanks T, Atkinson BL.  Comparison of cell viability on anorganic bone matrix with or without P-15 cell binding peptide.  Biomaterials  2004  25(19):4831-6  PubMed ID: 15120530   DOI: 10.1016/j.biomaterials.2003.12.007
6716  Yoshizawa T, Takizawa F, Iizawa F, Ishibashi O, Kawashima H, Matsuda A, Endo N, Kawashima H.  Homeobox protein MSX2 acts as a molecular defense mechanism for preventing ossification in ligament fibroblasts.  Mol Cell Biol  2004  24(8):3460-72  PubMed ID: 15060165   DOI: 10.1128/mcb.24.8.3460-3472.2004
6717  Simon CG Jr.  Imaging cells on polymer spherulites.  J Microsc  2004  216(Pt 2):153-5  PubMed ID: 15516226   DOI: 10.1111/j.0022-2720.2004.01401.x
6718  Washburn NR, Yamada KM, Simon CG Jr, Kennedy SB, Amis EJ.  High-throughput investigation of osteoblast response to polymer crystallinity: influence of nanometer-scale roughness on proliferation.  Biomaterials  2004  25(7-8):1215-24  PubMed ID: 14643595   DOI: 10.1016/j.biomaterials.2003.08.043
6719  Norio Amizuka et al  Morphological Approach to Biological Action of PTHrP and Vitamin D3 on Endochondral Ossification  Journal of Oral Biosciences  2004  46:79-96    DOI: 10.1016/S1349-0079(04)80020-3
6720  Ogasawara T, Kawaguchi H, Jinno S, Hoshi K, Itaka K, Takato T, Nakamura K, Okayama H.  Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6.  Mol Cell Biol.  2004  24(15):6560-8  PubMed ID: 15254224   DOI: 10.1128/MCB.24.15.6560-6568.2004
6721  Eelen G, Verlinden L, van Camp M, van Hummelen P, Marchal K, de Moor B, Mathieu C, Carmeliet G, Bouillon R, Verstuyf A.  The effects of 1alpha,25-dihydroxyvitamin D3 on the expression of DNA replication genes.  J Bone Miner Res  2004  19(1):133-46  PubMed ID: 14753745   DOI: 10.1359/JBMR.0301204
6722  Papoutsi Z, Kassi E, Papaevangeliou D, Pratsinis H, Zoumpourlis V, Halabalaki M, Mitakou S, Kalofoutis A, Moutsatsou P.  Plant 2-arylobenzofurans demonstrate a selective estrogen receptor modulator profile.  Steroids  2004  69(11-12):727-34  PubMed ID: 15579325   DOI: 10.1016/j.steroids.2004.07.005
6723  Keselowsky BG, Collard DM, García AJ.  Surface chemistry modulates focal adhesion composition and signaling through changes in integrin binding.  Biomaterials  2004  25(28):5947-54  PubMed ID: 15183609   DOI: 10.1016/j.biomaterials.2004.01.062
6724  Patil C, Zhu X, Rossa C Jr, Kim YJ, Kirkwood KL.  p38 MAPK regulates IL-1beta induced IL-6 expression through mRNA stability in osteoblasts.  Immunol Invest  2004  33(2):213-33  PubMed ID: 15195698   DOI: 10.1081/imm-120034231
6725  Xu HH, Simon CG Jr.  Self-hardening calcium phosphate composite scaffold for bone tissue engineering.  J Orthop Res  2004  22(3):535-43  PubMed ID: 15099632   DOI: 10.1016/j.orthres.2003.09.010
6726  Masayuki OKAZAKI  New Type Scaffold Biomaterials with Magnesium Accelerating Osteoblast Adhesion and Bone Formation  Journal of Oral Tissue Engineering  2004  1:31-40    DOI: 10.11223/jarde.1.31
6727  Hikiji H, Ishii S, Shindou H, Takato T, Shimizu T.  Absence of platelet-activating factor receptor protects mice from osteoporosis following ovariectomy.  J Clin Invest  2004  114(1):85-93  PubMed ID: 15232615   DOI: 10.1172/JCI20504
6729  Itoh M, Shimazu A, Hirata I, Yoshida Y, Shintani H, Okazaki M.  Characterization of CO3Ap-collagen sponges using X-ray high-resolution microtomography.  Biomaterials  2004  25(13):2577-83  PubMed ID: 14751743   DOI: 10.1016/j.biomaterials.2003.09.071
6730  Xu HH, Smith DT, Simon CG.  Strong and bioactive composites containing nano-silica-fused whiskers for bone repair.  Biomaterials  2004  25(19):4615-26  PubMed ID: 15120507   DOI: 10.1016/j.biomaterials.2003.12.058
6731  Tieliewuhan Y, Hirata I, Sasaki A, Minagi H, Okazaki M.  Osteoblast proliferation behavior and bone formation on and in CO3apatite-collagen sponges with a porous hydroxyapatite frame.  Dent Mater J  2004  23(3):258-64  PubMed ID: 15510851   DOI: 10.4012/dmj.23.258
6732  Taiji Adachit, Katsuya Sato, Mamoru Matsuo, and Yoshihiro Tomitai  Evaluation of Axial Strain in Stress Fibers Inducing Cytoskeletal Reorganization in Osteoblastic Cells(Micro- and Nano-biomechanics)  First Asian Pacific Conference on Biomechanics  2004     
6733  Xu HH, Simon CG Jr.  Self-hardening calcium phosphate cement-mesh composite: reinforcement, macropores, and cell response.  J Biomed Mater Res A  2004  69(2):267-78  PubMed ID: 15057999   DOI: 10.1002/jbm.a.20124
6734  Reyes CD, García AJ.  Alpha2beta1 integrin-specific collagen-mimetic surfaces supporting osteoblastic differentiation.  J Biomed Mater Res A  2004  69(4):591-600  PubMed ID: 15162400   DOI: 10.1002/jbm.a.30034
6735  Carl G. Simon Jr. William F. Guthrie Francis W. Wang  Cell seeding into calcium phosphate cement  Journal of Biomedical Materials Research Part A  2004  68A:628-639  PubMed ID: 14986318   DOI: 10.1002/jbm.a.20008
6736  Takada T, Suzuki N, Ito-Kato E, Noguchi Y, Ito M, Maeno M, Otsuka K  Effect of beta-alanyl-L-histidinato zinc on the differentiation of C2C12 cells.  Life Sci  2004  76(5):509-20  PubMed ID: 15556164   DOI: 10.1016/j.lfs.2004.06.014
6737  Naruse M, Otsuka E, Naruse M, Ishihara Y, Miyagawa-Tomita S, Hagiwara H.  Inhibition of osteoclast formation by 3-methylcholanthrene, a ligand for arylhydrocarbon receptor: suppression of osteoclast differentiation factor in osteogenic cells.  Biochem Pharmacol  2004  67(1):119-27  PubMed ID: 14667934   DOI: 10.1016/j.bcp.2003.08.038
6740  Shinsuke AOKI, Shunro YAMAGUCHI, Atsushi NAKAHIRA, Katsuaki SUGANUMA  Preparation of Porous Calcium Phosphates Using a Ceramic Foaming Technique Combined with a Hydrothermal Treatment and the Cell Response with Incorporation of Osteoblast-Like Cells  Journal of the Ceramic Society of Japan  2004  112:193-199    DOI: 10.2109/jcersj.112.193
5563  Shibata Y, Kawai H, Yamamoto H, Igarashi T, Miyazaki T.  Antibacterial titanium plate anodized by being discharged in NaCl solution exhibits cell compatibility  J Dent Res  2004  83(2):115-9  PubMed ID: 14742647   DOI: 10.1177/154405910408300206
5566  Kawazoe Y, Shiba T, Nakamura R, Mizuno A, Tsutsumi K, Uematsu T, Yamaoka M, Shindoh M, Kohgo T.  Induction of calcification in MC3T3-E1 cells by inorganic polyphosphate  J Dent Res  2004  83(8):613-8  PubMed ID: 15271969   DOI: 10.1177/154405910408300806
3017  Adachi T, Sato K, Tomita Y  Directional dependence of osteoblastic calcium response to mechanical stimuli.  Biomech Model Mechanobiol  2003  2:73-82  PubMed ID: 14586810   DOI: 10.1007/s10237-003-0029-0
3049  Mogi M, Togari A  Activation of caspases is required for osteoblastic differentiation.  J Biol Chem  2003  278:47477-82  PubMed ID: 12954609   DOI: 10.1074/jbc.M307055200
3050  Arai M., Nagasawa T., Tsunashima Y., Matsuda T., Kawamura H., Mogi M., Togari A.  A simple and useful method for evaluating biocompatibility of titanium alloy with heterotopic bone induced by demineralized bone matrix (DBM) pellet in mice.  Oral Therapeutics Pharmacology  2003  22:117-125   
6273  Tanigaki K, Sasaki S, Ohkuma S.  In bafilomycin A1-resistant cells, bafilomycin A1 raised lysosomal pH and both prodigiosins and concanamycin A inhibited growth through apoptosis.  FEBS Lett  2003  537(1-3):79-84  PubMed ID: 12606035   DOI: 10.1016/s0014-5793(03)00084-x
4964  Gruber R, Graninger W, Bobacz K, Watzek G, Erlacher L.  BMP-6-induced osteogenic differentiation of mesenchymal cell lines is not modulated by sex steroids and resveratrol.  Cytokine  2003  23(4-5):133-7  PubMed ID: 12967649   DOI: 10.1016/s1043-4666(03)00223-0
3535  Ehara A, Ogata K, Imazato S, Ebisu S, Nakano T, Umakoshi Y.  Effects of alpha-TCP and TetCP on MC3T3-E1 proliferation, differentiation and mineralization.  Biomaterials  2003  24(5):831-6  PubMed ID: 12485801   DOI: 10.1016/s0142-9612(02)00411-8
3870  Kim H, Arakawa H, Osada T, Ikai A.  Quantification of cell adhesion force with AFM: distribution of vitronectin receptors on a living MC3T3-E1 cell.  Ultramicroscopy  2003  97(1-4):359-63  PubMed ID: 12801689   DOI: 10.1016/S0304-3991(03)00061-5
3895  Isama K, Tsuchiya T.  Enhancing effect of poly(L-lactide) on the differentiation of mouse osteoblast-like MC3T3-E1 cells.  Biomaterials  2003  24(19):3303-9  PubMed ID: 12763458   DOI: 10.1016/s0142-9612(03)00216-3
4083  Saito M, Soshi S, Fujii K.  Effect of hyper- and microgravity on collagen post-translational controls of MC3T3-E1 osteoblasts.  J Bone Miner Res  2003  18(9):1695-705  PubMed ID: 12968680   DOI: 10.1359/jbmr.2003.18.9.1695
4415  Itoh F, Aoyagi S, Furihata-Komatsu H, Aoki M, Kusama H, Kojima M, Kogo H.  Clodronate stimulates osteoblast differentiation in ST2 and MC3T3-E1 cells and rat organ cultures.  Eur J Pharmacol  2003  477(1):9-16  PubMed ID: 14512092   DOI: 10.1016/j.ejphar.2003.08.011
4610  Suzuki H, Nezaki Y, Kuno E, Sugiyama I, Mizutani A, Tsukagoshi N.  Functional roles of the tissue inhibitor of metalloproteinase 3 (TIMP-3) during ascorbate-induced differentiation of osteoblastic MC3T3-E1 cells.  Biosci Biotechnol Biochem  2003  67(8):1737-43  PubMed ID: 12951508   DOI: 10.1271/bbb.67.1737
4766  Aoshima Y, Hasegawa Y, Hasegawa S, Nagasaka A, Kimura T, Hashimoto S, Torii Y, Tsukagoshi N.  Isolation of GnafC, a polysaccharide constituent of Gnaphalium affine, and synergistic effects of GnafC and ascorbate on the phenotypic expression of osteoblastic MC3T3-E1 cells.  Biosci Biotechnol Biochem  2003  67(10):2068-74  PubMed ID: 14586092   DOI: 10.1271/bbb.67.2068
4926  Bhattacharyya RS, Stern PH.  IGF-I and MAP kinase involvement in the stimulatory effects of LNCaP prostate cancer cell conditioned media on cell proliferation and protein synthesis in MC3T3-E1 osteoblastic cells.  J Cell Biochem  2003  90(5):925-37  PubMed ID: 14624452   DOI: 10.1002/jcb.10726
4952  Choi EM, Hwang JK.  Effects of (+)-catechin on the function of osteoblastic cells.  Biol Pharm Bull  2003  26(4):523-6  PubMed ID: 12673036   DOI: 10.1248/bpb.26.523
4955  Itano N, Okamoto S, Zhang D, Lipton SA, Ruoslahti E.  Cell spreading controls endoplasmic and nuclear calcium: a physical gene regulation pathway from the cell surface to the nucleus.  Proc Natl Acad Sci U S A  2003  100(9):5181-6  PubMed ID: 12702768   DOI: 10.1073/pnas.0531397100
4961  Takada T, Katagiri T, Ifuku M, Morimura N, Kobayashi M, Hasegawa K, Ogamo A, Kamijo R.  Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins.  J Biol Chem  2003  278(44):43229-35  PubMed ID: 12912996   DOI: 10.1074/jbc.M300937200
4978  Lee MH, Kwon TG, Park HS, Wozney JM, Ryoo HM.  BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2.  Biochem Biophys Res Commun  2003  309(3):689-94  PubMed ID: 12963046   DOI: 10.1016/j.bbrc.2003.08.058
5039  Murata T, Sugatani T, Shimizu K, Manganiello VC, Tagawa T.  Effect of the phosphodiesterase 4 inhibitor, rolipram, on retinoic acid-increased alkaline phosphatase activity in the mouse fibroblastic C3H10T1/2 cell line.  Arch Oral Biol  2003  48(1):63-7  PubMed ID: 12615143   DOI: 10.1016/s0003-9969(02)00166-8
5061  Yamasaki Y, Yoshida Y, Okazaki M, Shimazu A, Kubo T, Akagawa Y, Uchida T.  Action of FGMgCO3Ap-collagen composite in promoting bone formation.  Biomaterials  2003  24(27):4913-20  PubMed ID: 14559004   DOI: 10.1016/s0142-9612(03)00414-9
5091  Osada T, Uehara H, Kim H, Ikai A.  mRNA analysis of single living cells.  J Nanobiotechnology  2003  1(1):2  PubMed ID: 12646067   DOI: 10.1186/1477-3155-1-2
5465  Duarte WR, Shibata T, Takenaga K, Takahashi E, Kubota K, Ohya K, Ishikawa I, Yamauchi M, Kasugai S.  S100A4: a novel negative regulator of mineralization and osteoblast differentiation.  J Bone Miner Res  2003  18(3):493-501  PubMed ID: 12619934   DOI: 10.1359/jbmr.2003.18.3.493
5469  Meredith JC, Sormana JL, Keselowsky BG, García AJ, Tona A, Karim A, Amis EJ.  Combinatorial characterization of cell interactions with polymer surfaces.  J Biomed Mater Res A  2003  66(3):483-90  PubMed ID: 12918030   DOI: 10.1002/jbm.a.10004
5527  Tohjima E, Inoue D, Yamamoto N, Kido S, Ito Y, Kato S, Takeuchi Y, Fukumoto S, Matsumoto T.  Decreased AP-1 activity and interleukin-11 expression by bone marrow stromal cells may be associated with impaired bone formation in aged mice.  J Bone Miner Res  2003  18(8):1461-70  PubMed ID: 12929935   DOI: 10.1359/jbmr.2003.18.8.1461
6354  Ito T, Tokunaga K, Maruyama H, Kawashima H, Kitahara H, Horikoshi T, Ogose A, Hotta Y, Kuwano R, Katagiri H, Endo N.  Coxsackievirus and adenovirus receptor (CAR)-positive immature osteoblasts as targets of adenovirus-mediated gene transfer for fracture healing.  Gene Ther  2003  10(18):1623-8  PubMed ID: 12907955   DOI: 10.1038/
6457  Reyes CD, García AJ.  A centrifugation cell adhesion assay for high-throughput screening of biomaterial surfaces.  J Biomed Mater Res A  2003  67(1):328-33  PubMed ID: 14517892   DOI: 10.1002/jbm.a.10122
6574  Kirkwood K, Martin T, Andreadis ST, Kim YJ.  Chemically modified tetracyclines selectively inhibit IL-6 expression in osteoblasts by decreasing mRNA stability.  Biochem Pharmacol  2003  66(9):1809-19  PubMed ID: 14563491   DOI: 10.1016/s0006-2952(03)00450-7
6608  Cutler SM, García AJ.  Engineering cell adhesive surfaces that direct integrin alpha5beta1 binding using a recombinant fragment of fibronectin.  Biomaterials  2003  24(10):1759-70  PubMed ID: 12593958   DOI: 10.1016/s0142-9612(02)00570-7
6626  Verlinden L, Verstuyf A, Verboven C, Eelen G, De Ranter C, Gao LJ, Chen YJ, Murad I, Choi M, Yamamoto K, Yamada S, Van Haver D, Vandewalle M, De Clercq PJ, Bouillon R.  Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity.  J Biol Chem  2003  278(37):35476-82  PubMed ID: 12829710   DOI: 10.1074/jbc.M302045200
6628  Abe T, Hikiji H, Shin WS, Koshikiya N, Shima S, Nakata J, Susami T, Takato T, Toyo-oka T.  Targeting of iNOS with antisense DNA plasmid reduces cytokine-induced inhibition of osteoblastic activity.  Am J Physiol Endocrinol Metab  2003  285(3):E614-21  PubMed ID: 12657566   DOI: 10.1152/ajpendo.00267.2002
6646  Reyes CD, García AJ.  Engineering integrin-specific surfaces with a triple-helical collagen-mimetic peptide.  J Biomed Mater Res A  2003  65(4):511-23  PubMed ID: 12761842   DOI: 10.1002/jbm.a.10550
5561  Taira M, Nakao H, Takahashi J, Araki Y.  Effects of two vitamins, two growth factors and dexamethasone on the proliferation of rat bone marrow stromal cells and osteoblastic MC3T3-E1 cells  J Oral Rehabil  2003  30(7):697-701  PubMed ID: 12791154   DOI: 10.1046/j.1365-2842.2003.01118.x
2773  Sakiyama H, Nonaka T, Masuda R, Inoue N, Kuboki Y, Iijima M, Hirabayasi Y, Takahagi M, Yoshida K, Kuriiwa K, Yoshida M, Imajoh-Ohmi S  Characterization of mineral deposits formed in cultures of a hamster tartrate-resistant acid phosphatase (TRAP) and alkaline phosphatase (ALP) double-positive cell line (CCP).  Cell Tissue Res  2002  309:269-79  PubMed ID: 12172786   DOI: 10.1007/s00441-002-0587-y
3048  Ozeki, Nobuaki, Mogi, Makio, Nakamura, Hiroshi, Togari, Akifumi  Differential expression of the Fas-Fas ligand system on cytokine-induced apoptotic cell death in mouse osteoblastic cells.  Arch Oral Biol  2002  47:511-7  PubMed ID: 12208075   DOI: 10.1016/s0003-9969(02)00035-3
5980  Byers BA1, Pavlath GK, Murphy TJ, Karsenty G, García AJ.  Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal.  J Bone Miner Res  2002  17(11):1931-44  PubMed ID: 12412799   DOI: 10.1359/jbmr.2002.17.11.1931
3519  Higuchi C, Myoui A, Hashimoto N, Kuriyama K, Yoshioka K, Yoshikawa H, Itoh K.  Continuous inhibition of MAPK signaling promotes the early osteoblastic differentiation and mineralization of the extracellular matrix.  J Bone Miner Res  2002  17(10):1785-94  PubMed ID: 12369782   DOI: 10.1359/jbmr.2002.17.10.1785
3557  Tezuka K, Yasuda M, Watanabe N, Morimura N, Kuroda K, Miyatani S, Hozumi N.  Stimulation of osteoblastic cell differentiation by Notch.  J Bone Miner Res  2002  17(2):231-9  PubMed ID: 11811553   DOI: 10.1359/jbmr.2002.17.2.231
3560  Fujita T, Meguro T, Fukuyama R, Nakamuta H, Koida M.  New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP.  J Biol Chem  2002  277(25):22191-200  PubMed ID: 11956184   DOI: 10.1074/jbc.M110364200
3570  Shiroki K, Ohsawa C, Sugi N, Wakiyama M, Miura K, Watanabe M, Suzuki Y, Sugano S.  Internal ribosome entry site-mediated translation of Smad5 in vivo: requirement for a nuclear event.  Nucleic Acids Res  2002  30(13):2851-61  PubMed ID: 12087169   DOI: 10.1093/nar/gkf408
6667  Hata K, Sugawara F, Ohisa N, Takahashi S, Hori K.  Stimulative effects of (22E,24R)-ergosta-7,22-diene-3beta,5alpha,6beta-triol from fruiting bodies of Tricholoma auratum, on a mouse osteoblastic cell line, MC3T3-E1.  Biol Pharm Bull  2002  25(8):1040-4  PubMed ID: 12186406   DOI: 10.1248/bpb.25.1040
6668  Isama K, Tsuchiya T.  Effect of gamma-ray irradiated poly(L-lactide) on the differentiation of mouse osteoblast-like MC3T3-E1 cells.  J Biomater Sci Polym Ed  2002  13(2):153-66  PubMed ID: 12022747   DOI: 10.1163/156856202317414348
6670  Saito Y, Yoshizawa T, Takizawa F, Ikegame M, Ishibashi O, Okuda K, Hara K, Ishibashi K, Obinata M, Kawashima H.  A cell line with characteristics of the periodontal ligament fibroblasts is negatively regulated for mineralization and Runx2/Cbfa1/Osf2 activity, part of which can be overcome by bone morphogenetic protein-2.  J Cell Sci  2002  115(Pt 21):4191-200  PubMed ID: 12356921   DOI: 10.1242/jcs.00098
6671  Stephansson SN, Byers BA, García AJ.  Enhanced expression of the osteoblastic phenotype on substrates that modulate fibronectin conformation and integrin receptor binding.  Biomaterials  2002  23(12):2527-34  PubMed ID: 12033600   DOI: 10.1016/s0142-9612(01)00387-8
6672  Amizuka N, Oda K, Shimomura J, Maeda T.  Biological action of parathyroid hormone (PTH)-related peptide (PTHrP) mediated either by the PTH/PTHrP receptor or the nucleolar translocation in chondrocytes.  Anat Sci Int  2002  77(4):225-36  PubMed ID: 12557418   DOI: 10.1046/j.0022-7722.2002.00032.x
6673  Kuriyama K, Higuchi C, Tanaka K, Yoshikawa H, Itoh K.  A novel anti-rheumatic drug, T-614, stimulates osteoblastic differentiation in vitro and bone morphogenetic protein-2-induced bone formation in vivo.  Biochem Biophys Res Commun  2002  299(5):903-9  PubMed ID: 12470665   DOI: 10.1016/s0006-291x(02)02754-7
6674  Diniz P, Shomura K, Soejima K, Ito G.  Effects of pulsed electromagnetic field (PEMF) stimulation on bone tissue like formation are dependent on the maturation stages of the osteoblasts.  Bioelectromagnetics  2002  23(5):398-405  PubMed ID: 12111759   DOI: 10.1002/bem.10032
6675  Tsutsumimoto T, Wakabayashi S, Kinoshita T, Horiuchi H, Takaoka K.  A phosphodiesterase inhibitor, pentoxifylline, enhances the bone morphogenetic protein-4 (BMP-4)-dependent differentiation of osteoprogenitor cells.  Bone  2002  31(3):396-401  PubMed ID: 12231412   DOI: 10.1016/s8756-3282(02)00839-6
6676  Diniz P, Soejima K, Ito G.  Nitric oxide mediates the effects of pulsed electromagnetic field stimulation on the osteoblast proliferation and differentiation.  Nitric Oxide  2002  7(1):18-23  PubMed ID: 12175815   DOI: 10.1016/s1089-8603(02)00004-6
6678  Inoue A, Kobayashi Y, Ishizuka M, Hirose S, Hagiwara H.  Identification of a novel osteoblastic gene, inducible by C-type natriuretic peptide, whose transcript might function in mineralization as a noncoding RNA.  Calcif Tissue Int  2002  70(2):111-6  PubMed ID: 11870417   DOI: 10.1007/s00223-001-1012-3
6679  Hinoi E, Fujimori S, Takemori A, Yoneda Y.  Cell death by pyruvate deficiency in proliferative cultured calvarial osteoblasts.  Biochem Biophys Res Commun  2002  294(5):1177-83  PubMed ID: 12074601   DOI: 10.1016/S0006-291X(02)00578-8
6680  Kubota K, Sakikawa C, Katsumata M, Nakamura T, Wakabayashi K.  PDGF BB purified from osteoclasts acts as osteoblastogenesis inhibitory factor (OBIF).  J Biomol Tech  2002  13(2):62-71  PubMed ID: 19498968  
6681  K. Yamashita ; H. Morimoto ; M. Nakao ; H. Ukai ; T. Hanawa ; T. Ichikawa ; S. Kitamura  Intact extracellular matrix can be utilized for bio-integrated materials and tissue engineering  IEEE Xplore  2002      DOI: 10.1109/MCTE.2002.1175033
6682  Kubota K, Sakikawa C, Katsumata M, Nakamura T, Wakabayashi K.  Platelet-derived growth factor BB secreted from osteoclasts acts as an osteoblastogenesis inhibitory factor.  J Bone Miner Res  2002  17(2):257-65  PubMed ID: 11811556   DOI: 10.1359/jbmr.2002.17.2.257
6683  Yamasaki Y, Yoshida Y, Okazaki M, Shimazu A, Uchida T, Kubo T, Akagawa Y, Hamada Y, Takahashi J, Matsuura N.  Synthesis of functionally graded MgCO3 apatite accelerating osteoblast adhesion.  J Biomed Mater Res  2002  62(1):99-105  PubMed ID: 12124791   DOI: 10.1002/jbm.10220
6685  Onodera S, Nishihira J, Iwabuchi K, Koyama Y, Yoshida K, Tanaka S, Minami A.  Macrophage migration inhibitory factor up-regulates matrix metalloproteinase-9 and -13 in rat osteoblasts. Relevance to intracellular signaling pathways.  J Biol Chem  2002  277(10):7865-74  PubMed ID: 11751895   DOI: 10.1074/jbc.M106020200
6686  Naraba H, Yokoyama C, Tago N, Murakami M, Kudo I, Fueki M, Oh-Ishi S, Tanabe T.  Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1.  J Biol Chem  2002  277(32):28601-8  PubMed ID: 12034740   DOI: 10.1074/jbc.M203618200
6687  Kotani H, Kawaguchi H, Shimoaka T, Iwasaka M, Ueno S, Ozawa H, Nakamura K, Hoshi K.  Strong static magnetic field stimulates bone formation to a definite orientation in vitro and in vivo.  J Bone Miner Res  2002  17(10):1814-21  PubMed ID: 12369785   DOI: 10.1359/jbmr.2002.17.10.1814
6688  Naruse M, Ishihara Y, Miyagawa-Tomita S, Koyama A, Hagiwara H.  3-Methylcholanthrene, which binds to the arylhydrocarbon receptor, inhibits proliferation and differentiation of osteoblasts in vitro and ossification in vivo.  Endocrinology  2002  Sep;143(9):3575-81  PubMed ID: 12193573   DOI: 10.1210/en.2002-220003
6689  Simon CG Jr, Khatri CA, Wight SA, Wang FW.  Preliminary report on the biocompatibility of a moldable, resorbable, composite bone graft consisting of calcium phosphate cement and poly(lactide-co-glycolide) microspheres.  J Orthop Res  2002  0(3):473-82  PubMed ID: 12038620   DOI: 10.1016/S0736-0266(01)00140-1
6690  Washburn NR1, Simon CG Jr, Tona A, Elgendy HM, Karim A, Amis EJ.  Co-extrusion of biocompatible polymers for scaffolds with co-continuous morphology.  J Biomed Mater Res  2002  60(1):20-9  PubMed ID: 11835155   DOI: 10.1002/jbm.10049
6692  Wakabayashi S, Tsutsumimoto T, Kawasaki S, Kinoshita T, Horiuchi H, Takaoka K.  Involvement of phosphodiesterase isozymes in osteoblastic differentiation.  J Bone Miner Res  2002  17(2):249-56  PubMed ID: 11811555   DOI: 10.1359/jbmr.2002.17.2.249
6694  Fujimori S, Hinoi E, Yoneda Y.  Functional GABA(B) receptors expressed in cultured calvarial osteoblasts.  Biochem Biophys Res Commun  2002  293(5):1445-52  PubMed ID: 12054677   DOI: 10.1016/S0006-291X(02)00405-9
6695  Yoshiko Y, Aubin JE, Maeda N.  Stanniocalcin 1 (STC1) protein and mRNA are developmentally regulated during embryonic mouse osteogenesis: the potential of stc1 as an autocrine/paracrine factor for osteoblast development and bone formation.  J Histochem Cytochem  2002  50(4):483-92  PubMed ID: 11897801   DOI: 10.1177/002215540205000405
3016  Adachi, T. et al  Effect of Actin Filament on Deformation-Induced Ca2+ Response in Osteoblast-Like Cells  JSME International Journal, Series C  2001  44:914-919    DOI: 10.1299/jsmec.44.914
2480  Maeda T, Abe M, Kurisu K, Jikko A, Furukawa S  Molecular cloning and characterization of a novel gene, CORS26, encoding a putative secretory protein and its possible involvement in skeletal development.  J Biol Chem  2001  276:3628-34  PubMed ID: 11071891   DOI: 10.1074/jbc.M007898200
2487  Fujita T, Izumo N, Fukuyama R, Meguro T, Nakamuta H, Kohno T, Koida M  Phosphate provides an extracellular signal that drives nuclear export of Runx2/Cbfa1 in bone cells.  Biochem Biophys Res Commun  2001  280:348-52  PubMed ID: 11162521   DOI: 10.1006/bbrc.2000.4108
2557  Kusumi T, Nishi T, Tanaka M, Tsuchida S, Kudo H  A murine osteosarcoma cell line with a potential to develop ossification upon transplantation  Jpn J Cancer Res  2001  92:649-658  PubMed ID: 11429054   DOI: 10.1111/j.1349-7006.2001.tb01144.x
2771  Sakiyama H, Masuda R, Inoue N, Yamamoto K, Kuriiwa K, Nakagawa K, Yoshida K  Establishment and characterization of macrophage-like cell lines expressing osteoclast-specific markers.  J Bone Miner Metab  2001  19:220-7  PubMed ID: 11448014   DOI: 10.1007/s007740170024
3542  Ito H, Akiyama H, Iguchi H, Iyama K, Miyamoto M, Ohsawa K, Nakamura T.  Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilage.  J Biol Chem  2001  276(26):24023-9  PubMed ID: 11292829   DOI: 10.1074/jbc.M100861200
3552  Izumo N, Fujita T, Nakamuta H, Koida M.  Lipophilic statins can be osteogenic by promoting osteoblastic calcification in a Cbfa1- and BMP-2-independent manner.  Methods Find Exp Clin Pharmacol  2001  23(7):389-94  PubMed ID: 11771853   DOI: 10.1358/mf.2001.23.7.662123
6649  Lee DH, Park JC, Suh H.  Effect of centrifugal force on cellular activity of osteoblastic MC3T3-E1 cells in vitro.  Yonsei Med J  2001  42(4):405-10  PubMed ID: 11519082   DOI: 10.3349/ymj.2001.42.4.405
6650  Mizutani A, Sugiyama I, Kuno E, Matsunaga S, Tsukagoshi N.  Expression of matrix metalloproteinases during ascorbate-induced differentiation of osteoblastic MC3T3-E1 cells.  J Bone Miner Res  2001  16(11):2043-9  PubMed ID: 11697800   DOI: 10.1359/jbmr.2001.16.11.2043
6651  Kanno S, Anuradha CD, Hirano S.  Chemotactic responses of osteoblastic MC3T3-E1 cells toward zinc chloride.  Biol Trace Elem Res  2001  83(1):49-55  PubMed ID: 11694002   DOI: 10.1385/BTER:83:1:49
6652  Ishibashi O, Yamagishi T, Hanada K, Kawashima H.  Tamoxifen agonism and estrogen antagonism of c-fos gene promoter activity through non-consensus-responsive elements in MC3T3-E1 osteoblasts.  Biochem Biophys Res Commun  2001  289(3):705-11  PubMed ID: 11726205   DOI: 10.1006/bbrc.2001.6045
6653  Hattori T, Maehashi H, Miyazawa T, Naito M.  Potentiation by stannous chloride of calcium entry into osteoblastic MC3T3-E1 cells through voltage-dependent L-type calcium channels.  Cell Calcium  2001  30(1):67-72  PubMed ID: 11396989   DOI: 10.1054/ceca.2001.0214
6654  Ishibashi O, Kawashima H.  Cloning and characterization of the functional promoter of mouse estrogen receptor beta gene.  Biochim Biophys Acta  2001  1519(3):223-9  PubMed ID: 11418189   DOI: 10.1016/s0167-4781(01)00232-9
6264  Mody 1, Parhami F, Sarafian TA, Demer LL.  Oxidative stress modulates osteoblastic differentiation of vascular and bone cells.  Free Radic Biol Med  2001  31(4):509-19  PubMed ID: 11498284   DOI: 10.1016/s0891-5849(01)00610-4
6655  Makiishi-Shimobayashi C, Tsujimura T, Iwasaki T, Yamada N, Sugihara A, Okamura H, Hayashi S, Terada N.  Interleukin-18 up-regulates osteoprotegerin expression in stromal/osteoblastic cells.  Biochem Biophys Res Commun  2001  281(2):361-6  PubMed ID: 11181055   DOI: 10.1006/bbrc.2001.4380
6656  Taira M, Toguchi MS, Hamada Y, Takahashi J, Itou R, Toyosawa S, Ijyuin N, Okazaki M.  Studies on cytotoxic effect of nickel ions on three cultured fibroblasts.  J Mater Sci Mater Med  2001  12(5):373-6  PubMed ID: 15348274   DOI: 10.1023/a:1011295115612
6657  Kikuchi T, Matsuguchi T, Tsuboi N, Mitani A, Tanaka S, Matsuoka M, Yamamoto G, Hishikawa T, Noguchi T, Yoshikai Y.  Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors.  J Immunol  2001  166(5):3574-9  PubMed ID: 11207318   DOI: 10.4049/jimmunol.166.5.3574
6658  Davis J, Pither RJ.  Biochemical responses in cultured cells following exposure to (89)SrCl(2): potential relevance to the mechanism of action in pain palliation.  Eur J Cancer  2001  37(18):2464-9  PubMed ID: 11720844   DOI: 10.1016/s0959-8049(01)00305-7
6659  Tamura S, Kataoka H, Matsui Y, Shionoya Y, Ohno K, Michi KI, Takahashi K, Yamaguchi A.  The effects of transplantation of osteoblastic cells with bone morphogenetic protein (BMP)/carrier complex on bone repair.  Bone  2001  29(2):169-75  PubMed ID: 11502479   DOI: 10.1016/s8756-3282(01)00498-7
6660  Fujita T, Fukuyama R, Izumo N, Hirai T, Meguro T, Nakamuta H, Koida M.  Transactivation of core binding factor alpha1 as a basic mechanism to trigger parathyroid hormone-induced osteogenesis.  Jpn J Pharmacol  2001  86(4):405-16  PubMed ID: 11569614   DOI: 10.1254/jjp.86.405
3047  Mogi M, Kondo A, Kinpara K, Togari A  Anti-apoptotic action of nerve growth factor in mouse osteoblastic cell line.  Life Sci  2000  67:1197-206  PubMed ID: 10954053   DOI: 10.1016/s0024-3205(00)00705-0
2484  Taira M, Nakao H, Matsumoto T, Takahashi J  Cytotoxic effect of methyl methacrylate on 4 cultured fibroblasts.  Int J Prosthodont  2000  13:311-5  PubMed ID: 11203647  
3976  Horikawa A, Okada K, Sato K, Sato M.  Morphological changes in osteoblastic cells (MC3T3-E1) due to fluid shear stress: cellular damage by prolonged application of fluid shear stress.  Tohoku J Exp Med  2000  191(3):127-37  PubMed ID: 10997553   DOI: 10.1620/tjem.191.127
3977  Ikarashi Y, Tsuchiya T, Nakamura A.  Effect of heat treatment of poly(L-lactide) on the response of osteoblast-like MC3T3-E1 cells.  Biomaterials  2000  21(12):1259-67  PubMed ID: 10811307   DOI: 10.1016/s0142-9612(00)00008-9
3978  Tanioka T, Nakatani Y, Semmyo N, Murakami M, Kudo I.  Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis.  J Biol Chem  2000  275(42):32775-82  PubMed ID: 10922363   DOI: 10.1074/jbc.M003504200
3980  Hiroko Kotani, Masakazu Iwasaka, and Shoogo Ueno  Magnetic orientation of collagen and bone mixture  Journal of Applied Physics  2000  87:6191    DOI: 10.1063/1.372652
3981  Ura K, Morimoto I, Watanabe K, Saito K, Yanagihara N, Eto S.  Interleukin (IL)-4 and IL-13 inhibit the differentiation of murine osteoblastic MC3T3-E1 cells.  Endocr J  2000  47(3):293-302  PubMed ID: 11036873   DOI: 10.1507/endocrj.47.293
3982  Nakatani Y, Tanioka T, Sunaga S, Murakami M, Kudo I.  Identification of a cellular protein that functionally interacts with the C2 domain of cytosolic phospholipase A(2)alpha.  J Biol Chem  2000  275(2):1161-8  PubMed ID: 10625659   DOI: 10.1074/jbc.275.2.1161
3983  Ikarashi Y, Tsuchiya T, Kaniwa M, Nakamura A.  Activation of osteoblast-like MC3T3-E1 cell responses by poly(lactide).  Biol Pharm Bull  2000  23(12):1470-6  PubMed ID: 11145180   DOI: 10.1248/bpb.23.1470
3985  Hines ER, Collins JF, Ghishan FK.  Molecular cloning of the murine PHEX gene promoter.  Biochim Biophys Acta  2000  1493(3):333-6  PubMed ID: 11018258   DOI: 10.1016/s0167-4781(00)00188-3
3986  Davis J1, Cook ND, Pither RJ.  Biologic mechanisms of 89SrCl2 incorporation into type I collagen during bone mineralization.  J Nucl Med  2000  41(1):183-8  PubMed ID: 10647622  
3987  Gruber R, Nothegger G, Ho GM, Willheim M, Peterlik M.  Differential stimulation by PGE(2) and calcemic hormones of IL-6 in stromal/osteoblastic cells.  Biochem Biophys Res Commun  2000  270(3):1080-5  PubMed ID: 10772953   DOI: 10.1006/bbrc.2000.2573
3989  Yoshimasa FUJIMAKI  The Role of Recombinant Human Bone Morphogenetic Protein 2 (rhBMP-2) in the Differentiation of Osteoblasts and Chondrocytes  The Showa University Journal of Medical Sciences  2000  12:39-49    DOI: 10.15369/sujms1989.12.39
3990  Takami M, Takahashi N, Udagawa N, Miyaura C, Suda K, Woo JT, Martin TJ, Nagai K, Suda T.  Intracellular calcium and protein kinase C mediate expression of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in osteoblasts.  Endocrinology  2000  141(12):4711-9  PubMed ID: 11108286   DOI: 10.1210/endo.141.12.7852
3992  Chien HH, Lin WL, Cho MI.  Down-regulation of osteoblastic cell differentiation by epidermal growth factor receptor.  Calcif Tissue Int  2000  67(2):141-50  PubMed ID: 10920219   DOI: 10.1007/s00223001128
3055  M. Arai et al  The release of alkaline phosphatase from osteoblastic cells stimulated by calcium ionophore A23187  Asia Pacific Journal of Pharmacology  2000  14(4):117-119   
16342  Jackson SM, Demer LL.  Peroxisome proliferator-activated receptor activators modulate the osteoblastic maturation of MC3T3-E1 preosteoblasts  FEBS Lett  2000  471(1):119-24  PubMed ID: 10760525   DOI: 10.1016/s0014-5793(00)01372-7
12454  Balint E, Marshall CF, Sprague SM.  Role of interleukin-6 in beta2-microglobulin-induced bone mineral dissolution  Kidney Int  2000  57(4):1599-607  PubMed ID: 10760095   DOI: 10.1046/j.1523-1755.2000.00004.x
3292  Kinpara K, Mogi M, Kuzushima M, Togari A.  IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-gamma  J Immunol  2000  164(11):5833-43  PubMed ID: 10820262   DOI: 10.4049/jimmunol.164.11.5833
5578  Baba TT.  Restoration of mineral depositions by dexamethasone in the matrix of nonmineralizing osteoblastic cells subcloned from MC3T3-E1 cells  Calcif Tissue Int  2000  67(5):416-21  PubMed ID: 11136541   DOI: 10.1007/s002230001157
3046  Mogi M, Kinpara K, Kondo A, Togari A  Involvement of nitric oxide and biopterin in proinflammatory cytokine-induced apoptotic cell death in mouse osteoblastic cell line MC3T3-E1.  Biochem Pharmacol  1999  58:649-54  PubMed ID: 10413302   DOI: 10.1016/s0006-2952(99)00131-8
2420  Yuhara S, Kasagi S, Inoue A, Otsuka E, Hirose S, Hagiwara H  Effects of nicotine on cultured cells suggest that it can influence the formation and resorption of bone.  Eur J Pharmacol  1999  383:387-93  PubMed ID: 10594333   DOI: 10.1016/s0014-2999(99)00551-8
3955  Tsutsumimoto T, Kawasaki S, Ebara S, Takaoka K.  TNF-alpha and IL-1beta suppress N-cadherin expression in MC3T3-E1 cells.  J Bone Miner Res.  1999  14(10):1751-60  PubMed ID: 10491223   DOI: 10.1359/jbmr.1999.14.10.1751
3956  Kage K, Fujita N, Oh-hara T, Ogata E, Fujita T, Tsuruo T.  Basic fibroblast growth factor induces cyclooxygenase-2 expression in endothelial cells derived from bone.  Biochem Biophys Res Commun  1999  254(1):259-63  PubMed ID: 9920767   DOI: 10.1006/bbrc.1998.9875
3958  Parhami F, Jackson SM, Tintut Y, Le V, Balucan JP, Territo M, Demer LL.  Atherogenic diet and minimally oxidized low density lipoprotein inhibit osteogenic and promote adipogenic differentiation of marrow stromal cells.  J Bone Miner Res  1999  14(12):2067-78  PubMed ID: 10620066   DOI: 10.1359/jbmr.1999.14.12.2067
3959  Tintut Y, Parhami F, Le V, Karsenty G, Demer LL.  Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells. Ubiquitin/proteasome-dependent regulation.  J Biol Chem  1999  274(41):28875-9  PubMed ID: 10506130   DOI: 10.1074/jbc.274.41.28875
3961  Daci E, Udagawa N, Martin TJ, Bouillon R, Carmeliet G.  The role of the plasminogen system in bone resorption in vitro.  J Bone Miner Res  1999  14(6):946-52  PubMed ID: 10352103   DOI: 10.1359/jbmr.1999.14.6.946
3963  Amizuka N, Kwan MY, Goltzman D, Ozawa H, White JH.  Vitamin D3 differentially regulates parathyroid hormone/parathyroid hormone-related peptide receptor expression in bone and cartilage.  J Clin Invest  1999  103(3):373-81  PubMed ID: 9927498   DOI: 10.1172/JCI3265
3964  Nagai M, Sato N.  Reciprocal gene expression of osteoclastogenesis inhibitory factor and osteoclast differentiation factor regulates osteoclast formation.  Biochem Biophys Res Commun  1999  257(3):719-23  PubMed ID: 10208850   DOI: 10.1006/bbrc.1999.0524
3965  Onodera S, Suzuki K, Kaneda K, Fujinaga M, Nishihira J.  Growth factor-induced expression of macrophage migration inhibitory factor in osteoblasts: relevance to the plasminogen activator system.  Semin Thromb Hemost  1999  25(6):563-8  PubMed ID: 10632479   DOI: 10.1055/s-2007-994966
3966  Takumi Nakagawa Naoya Fujita Tomoko Oh‐Hara Takahide Kurokawa Kozo Nakamura Takashi Tsuruo  Interleukin‐1α induces cyclooxygenase‐2 expression in bone‐derived endothelial cells  JOURNAL OF CELLULAR PHYSIOLOGY  1999  179:226-232  PubMed ID: 10199562   DOI: 10.1002/(SICI)1097-4652(199905)179:2<226::AID-JCP13>3.0.CO;2-Q
2356  Kato, H., Ypnezawa, T., Shirai, H., Sano, K., Abe, M.  An Improved Method for the Evaluation of the Effects of Laser Irradiation on Cultured Osteoblastic Cells  Bull Osaka Med Coll  1998  44:19-26   
2272  Fujishige K, Yanaka N, Akatsuka H, Omori K  Localization of clearance receptor in rat lung and trachea : association with chondrogenic differentiation  Am J Physiol  1998  274(3 Pt 1):425-431  PubMed ID: 9530179   DOI: 10.1152/ajplung.1998.274.3.L425
3940  Mizutani K, Ikeda K, Kawai Y, Yamori Y.  Resveratrol stimulates the proliferation and differentiation of osteoblastic MC3T3-E1 cells.  Biochem Biophys Res Commun.  1998  253(3):859-63  PubMed ID: 9918820   DOI: 10.1006/bbrc.1998.9870
3941  Nishimura N, Kawai T.  Effect of microstructure of titanium surface on the behaviour of osteogenic cell line MC3T3-E1.  J Mater Sci Mater Med   1998  9(2):99-102  PubMed ID: 15348915   DOI: 10.1023/a:1008851115846
3942  Motomura T, Kasayama S, Takagi M, Kurebayashi S, Matsui H, Hirose T, Miyashita Y, Yamauchi-Takihara K, Yamamoto T, Okada S, Kishimoto T.  Increased interleukin-6 production in mouse osteoblastic MC3T3-E1 cells expressing activating mutant of the stimulatory G protein.  J Bone Miner Res.  1998  13(7):1084-91  PubMed ID: 9661072   DOI: 10.1359/jbmr.1998.13.7.1084
3943  Murakami T, Yamamoto M, Ono K, Nishikawa M, Nagata N, Motoyoshi K, Akatsu T.  Transforming growth factor-beta1 increases mRNA levels of osteoclastogenesis inhibitory factor in osteoblastic/stromal cells and inhibits the survival of murine osteoclast-like cells.  Biochem Biophys Res Commun.   1998  252(3):747-52  PubMed ID: 9837778   DOI: 10.1006/bbrc.1998.9723
3944  Matsumura S, Hiranuma H, Deguchi A, Maeda T, Jikko A, Fuchihata H.  Changes in phenotypic expression of osteoblasts after X irradiation.  Radiat Res  1998  149(5):463-71  PubMed ID: 9588357  
3945  Ogikubo O, Maeda T, Yamane T, Ohtsuka T, Ohkubo I, Takahashi S, Ohnishi S, Matsui N.  Regulation of Zn-alpha2-glycoprotein-mediated cell adhesion by kininogens and their derivatives.  Biochem Biophys Res Commun  1998  252(1):257-62  PubMed ID: 9813179   DOI: 10.1006/bbrc.1998.9614
3946  Yoshikawa H, Taniguchi SI, Yamamura H, Mori S, Sugimoto M, Miyado K, Nakamura K, Nakao K, Katsuki M, Shibata N, Takahashi K.  Mice lacking smooth muscle calponin display increased bone formation that is associated with enhancement of bone morphogenetic protein responses.  Genes Cells  1998  3(10):685-95  PubMed ID: 9893025   DOI: 10.1046/j.1365-2443.1998.00214.x
3949  Yasuda H, Shima N, Nakagawa N, Mochizuki SI, Yano K, Fujise N, Sato Y, Goto M, Yamaguchi K, Kuriyama M, Kanno T, Murakami A, Tsuda E, Morinaga T, Higashio K.  Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro.  Endocrinology.  1998  139(3):1329-37  PubMed ID: 9492069   DOI: 10.1210/endo.139.3.5837
15427  Migliaccio S, Bernardini S, Wetsel WC, Korach KS, Faraggiana T, Teti A.  Protein kinase C modulates estrogen receptors in differentiated osteoblastic cells in vitro  Steroids  1998  63(5-6):352-4  PubMed ID: 9618801   DOI: 10.1016/s0039-128x(98)00040-3
3931  Okahashi N, Nakamura I, Jimi E, Koide M, Suda T, Nishihara T.  Specific inhibitors of vacuolar H(+)-ATPase trigger apoptotic cell death of osteoclasts.  J Bone Miner Res  1997  12(7):1116-23  PubMed ID: 9200012   DOI: 10.1359/jbmr.1997.12.7.1116
3932  Murakami M, Kuwata H, Amakasu Y, Shimbara S, Nakatani Y, Atsumi G, Kudo I.  Prostaglandin E2 amplifies cytosolic phospholipase A2- and cyclooxygenase-2-dependent delayed prostaglandin E2 generation in mouse osteoblastic cells. Enhancement by secretory phospholipase A2.  J Biol Chem  1997  272(32):19891-7  PubMed ID: 9242654   DOI: 10.1074/jbc.272.32.19891
3933  Parhami F, Morrow AD, Balucan J, Leitinger N, Watson AD, Tintut Y, Berliner JA, Demer LL.  Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation. A possible explanation for the paradox of arterial calcification in osteoporotic patients.  Arterioscler Thromb Vasc Biol  1997  17(4):680-7  PubMed ID: 9108780   DOI: 10.1161/01.atv.17.4.680
3934  Takagi M, Kasayama S, Yamamoto T, Motomura T, Hashimoto K, Yamamoto H, Sato B, Okada S, Kishimoto T.  Advanced glycation endproducts stimulate interleukin-6 production by human bone-derived cells.  J Bone Miner Res  1997  12(3):439-46  PubMed ID: 9076587   DOI: 10.1359/jbmr.1997.12.3.439
3935  Stulc T, Klement D, Kvasnicka J, Stepán JJ.  Immunocytochemical detection of estrogen receptors in bone cells using flow cytometry.  Biochim Biophys Acta  1997  1356(1):95-100  PubMed ID: 9099995   DOI: 10.1016/s0167-4889(96)00152-8
3925  Mizuno M, Fujisawa R, Kuboki Y.  Bone chondroadherin promotes attachment of osteoblastic cells to solid-state substrates and shows affinity to collagen.  Calcif Tissue Int  1996  59(3):163-7  PubMed ID: 8694892   DOI: 10.1007/s002239900103
3928  Murakami M, Nakatani Y, Kudo I.  Type II secretory phospholipase A2 associated with cell surfaces via C-terminal heparin-binding lysine residues augments stimulus-initiated delayed prostaglandin generation.  J Biol Chem.  1996  271(47):30041-51  PubMed ID: 8939951   DOI: 10.1074/jbc.271.47.30041

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