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Cell No. : Cell Name
RCB1124 : OP9  update : 2024/10/04
CommentSupport hematpoietic stem cell and ES cell differentiation to blood cells and lymphocytes.
Comment from the depositor
Terms and conditionsBasically, there is no restriction regarding academic use. For commercial use or patent application, please contact Rebirthel Co., Ltd. (info@rebirthel.com).
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Kodama, H. & Nakano, T.
Originator Kodama, Hiroaki
Year of deposit 1994
Animal _mouse < Mammals
Strain name B6C3Fe-a/a, op
Gender Unknown
Age at sampling 0 day
Tissue newborn, calvaria
Genetics op/op
Classification other
Lifespan infinite
Morphology fibroblast-like
Cellosaurus(Expasy) CVCL_4398
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Culture medium MEM ALPHA + 20% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 2-4 split
SC frequency Subculture or Medium Renewal : once/2 days
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
SSLP(mouse) OK
Images
deposit info
lot info
Reference information Reference 0
User's Publication 78


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Reference

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User's Publication
21647  Matsui Y, Muramatsu F, Nakamura H, Noda Y, Matsumoto K, Kishima H, Takakura N.  Brain-derived endothelial cells are neuroprotective in a chronic cerebral hypoperfusion mouse model.  Commun Biol  2024  7(1):338  PubMed ID: 38499610   DOI: 10.1038/s42003-024-06030-x
21183  Xiao L, Mochizuki M, Wang D, Shimamura N, Sunada K, Nakahara T.  Types of cell culture inserts affect cell crosstalk between co-cultured macrophages and adipocytes.  Biochem Biophys Res Commun  2023  658:10-17  PubMed ID: 37011478   DOI: 10.1016/j.bbrc.2023.03.068
21350  Shimizu S, Iba T, Naito H, Rahmawati FN, Konishi H, Jia W, Muramatsu F, Takakura N.  Aging impairs the ability of vascular endothelial stem cells to generate endothelial cells in mice.  Angiogenesis  2023    PubMed ID: 37563497   DOI: 10.1007/s10456-023-09891-8
21385  Rahmawati FN, Iba T, Naito H, Shimizu S, Konishi H, Jia W, Takakura N.  Single-cell sequencing reveals the existence of fetal vascular endothelial stem cell-like cells in mouse liver.  Stem Cell Res Ther  2023  14(1):227  PubMed ID: 37649114   DOI: 10.1186/s13287-023-03460-y
20079  Miyoshi H, Abo K, Hosoya D, Matsuo K, Utsumi Y.  Effects of mouse fetal liver cell culture density on hematopoietic cell expansion in three-dimensional cocultures with stromal cells.  Int J Artif Organs  2022  391398821996377  PubMed ID: 33611956   DOI: 10.1177/0391398821996377
20628  Xiao L, Mochizuki M, Fan Y, Nakahara T, Liao F.  Enzyme-digested Colla Corii Asini (E'jiao) suppresses lipopolysaccharide-induced inflammatory changes in THP-1 macrophages and OP9 adipocytes.  Hum Cell  2022    PubMed ID: 35359251   DOI: 10.1007/s13577-022-00694-5
20636  Wakabayashi T, Naito H, Iba T, Nishida K, Takakura N.  Identification of CD157-Positive Vascular Endothelial Stem Cells in Mouse Retinal and Choroidal Vessels: Fluorescence-Activated Cell Sorting Analysis.  Invest Ophthalmol Vis Sci  2022  63(4):5  PubMed ID: 35394492   DOI: 10.1167/iovs.63.4.5
20033  Nita A, Muto Y, Katayama Y, Matsumoto A, Nishiyama M, Nakayama KI.  The autism-related protein CHD8 contributes to the stemness and differentiation of mouse hematopoietic stem cells.  Cell Rep  2021  34(5):108688  PubMed ID: 33535054   DOI: 10.1016/j.celrep.2021.108688
20107  Jia W, Kong L, Kidoya H, Naito H, Muramatsu F, Hayashi Y, Hsieh HY, Yamakawa D, Hsu DK, Liu FT, Takakura N.  Indispensable role of Galectin-3 in promoting quiescence of hematopoietic stem cells.  Nat Commun  2021  12(1):2118  PubMed ID: 33837181   DOI: 10.1038/s41467-021-22346-2
20121  Xiao L, Miwa N.  Hydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents.  Cells  2021  10(3)  PubMed ID: 33799840   DOI: 10.3390/cells10030626
14074  Mu A, Hira A, Niwa A, Osawa M, Yoshida K, Mori M, Okamoto Y, Inoue K, Kondo K, Kanemaki MT, Matsuda T, Ito E, Kojima S, Nakahata T, Ogawa S, Tanaka K, Matsuo K, Saito MK, Takata M.  Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency  Blood  2021  137(15):2021-2032  PubMed ID: 33512438   DOI: 10.1182/blood.2020009111
17082  Oba T, Makino K, Kajihara R, Yokoi T, Araki R, Abe M, Minderman H, Chang AE, Odunsi K, Ito F.  In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models  J Immunother Cancer  2021  9(5):e002432  PubMed ID: 34049930   DOI: 10.1136/jitc-2021-002432
10005  Soki Kashima, Takuya Maeda, Kyoko Masuda, Seiji Nagano, Takamitsu Inoue, Masashi Takeda, Yuka Kono, Takashi Kobayashi, Shigeyoshi Saito, Takahiro Higuchi, Hiroshi Ichise, Yuka Kobayashi, Keiko Iwaisako, Koji Terada, Yasutoshi Agata, Kazuyuki Numakura, Mitsuru Saito, Shintaro Narita, Masaki Yasukawa, Osamu Ogawa, Tomonori Habuchi, Hiroshi Kawamoto  Cytotoxic T Lymphocytes Regenerated From iPS Cells Have Therapeutic Efficacy in a Patient-Derived Xenograft Solid Tumor Model  iScience  2020  23(4):100998  PubMed ID: 32259478   DOI: 10.1016/j.isci.2020.100998
11925  Wakao H.  Reprogramming of MAIT Cells to Pluripotency and Redifferentiation.  Methods Mol. Biol.  2020    PubMed ID: 31792827   DOI: 10.1007/978-1-0716-0207-2_16
12032  Naito H, Wakabayashi T, Ishida M, Gil CH, Iba T, Rahmawati FN, Shimizu S, Yoder MC, Takakura N.  Isolation of tissue-resident vascular endothelial stem cells from mouse liver.  Nat Protoc  2020    PubMed ID: 32005982   DOI: 10.1038/s41596-019-0276-x
12168  Kana Kuronuma, Aya Yokoi, Tomoya Fukuoka, Muneaki Miyata, Akio Maekawa, Satowa Tanaka, Leo Matsubara, Chie Goto, Miki Matsuo, Hao-Wei Han, Mai Tsuruta, Haruka Murata, Hikari Okamoto, Natsumi Hasegawa, Shigetaka Asano, Mitsuhiro Ito  Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-4  Heliyon  2020    PubMed ID: 32322728   DOI: 10.1016/j.heliyon.2020.e03743
14798  Kondo T, Ando M, Nagai N, Tomisato W, Srirat T, Liu B, Mise-Omata S, Ikeda M, Chikuma S, Nishimasu H, Nureki O, Ohmura M, Hayakawa N, Hishiki T, Uchibori R, Ozawa K, Yoshimura A.  The NOTCH-FOXM1 Axis Plays a Key Role in Mitochondrial Biogenesis in the Induction of Human Stem Cell Memory-like CAR-T Cells  Cancer Res  2020  80(3):471-483  PubMed ID: 31767627   DOI: 10.1158/0008-5472.CAN-19-1196
4047  Naito H, Iba T, Wakabayashi T, Tai-Nagara I, Suehiro JI, Jia W, Eino D, Sakimoto S, Muramatsu F, Kidoya H, Sakurai H, Satoh T, Akira S, Kubota Y, Takakura N.  TAK1 Prevents Endothelial Apoptosis and Maintains Vascular Integrity  Dev Cell  2019  48(2):151-166  PubMed ID: 30639056   DOI: 10.1016/j.devcel.2018.12.002
11544  Iba T, Naito H, Shimizu S, Rahmawati FN, Wakabayashi T, Takakura N.  Isolation of tissue-resident endothelial stem cells and their use in regenerative medicine.  Inflamm Regen  2019    PubMed ID: 31086611   DOI: 10.1186/s41232-019-0098-9
12535  Tsukamoto T.  HIV Impacts CD34 + Progenitors Involved in T-Cell Differentiation During Coculture With Mouse Stromal OP9-DL1 Cells  Front Immunol  2019  10:81  PubMed ID: 30761146   DOI: 10.3389/fimmu.2019.00081
7000  Wakabayashi T, Naito H, Suehiro JI, Lin Y, Kawaji H, Iba T, Kouno T, Ishikawa-Kato S, Furuno M, Takara K, Muramatsu F, Weizhen J, Kidoya H, Ishihara K, Hayashizaki Y, Nishida K, Yoder MC, Takakura N.  CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties.  Cell Stem Cell  2018  22(3):384-397  PubMed ID: 29429943   DOI: 10.1016/j.stem.2018.01.010
10826  Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M, Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi H, Hirao A.  Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress.  Cell Stem Cell  2018  22:713-725.e8  PubMed ID: 29706577   DOI: 10.1016/j.stem.2018.04.002
14825  Eino D, Tsukada Y, Naito H, Kanemura Y, Iba T, Wakabayashi T, Muramatsu F, Kidoya H, Arita H, Kagawa N, Fujimoto Y, Takara K, Kishima H, Takakura N.  LPA4-Mediated Vascular Network Formation Increases the Efficacy of Anti-PD-1 Therapy against Brain Tumors  Cancer Res  2018  78(23):6607-6620  PubMed ID: 30301839   DOI: 10.1158/0008-5472.CAN-18-0498
10294  Nishimura T, Unezaki N, Kanegi R, Wijesekera DPH, Hatoya S, Sugiura K, Kawate N, Tamada H, Imai H, Inaba T.  Generation of Canine Induced Extraembryonic Endoderm-Like Cell Line That Forms Both Extraembryonic and Embryonic Endoderm Derivatives.  Stem Cells Dev.  2017  26:1111-1120  PubMed ID: 28474540   DOI: 10.1089/scd.2017.0026
14736  Takara K, Eino D, Ando K, Yasuda D, Naito H, Tsukada Y, Iba T, Wakabayashi T, Muramatsu F, Kidoya H, Fukuhara S, Mochizuki N, Ishii S, Kishima H, Takakura N.  Lysophosphatidic Acid Receptor 4 Activation Augments Drug Delivery in Tumors by Tightening Endothelial Cell-Cell Contact  Cell Rep  2017  20(9):2072-2086  PubMed ID: 28854359   DOI: 10.1016/j.celrep.2017.07.080
7053  Maeda T, Nagano S, Ichise H, Kataoka K, Yamada D, Ogawa S, Koseki H, Kitawaki T, Kadowaki N, Takaori-Kondo A, Masuda K, Kawamoto H.  Regeneration of CD8αβ T Cells from T-cell-Derived iPSC Imparts Potent Tumor Antigen-Specific Cytotoxicity.  Cancer Res.  2016  76:6839-6850  PubMed ID: 27872100   DOI: 10.1158/0008-5472.CAN-16-1149
9643  Naito H, Wakabayashi T, Kidoya H, Muramatsu F, Takara K, Eino D, Yamane K, Iba T, Takakura N.  Endothelial Side Population Cells Contribute to Tumor Angiogenesis and Antiangiogenic Drug Resistance.  Cancer Res.  2016  76:3200-10  PubMed ID: 27197162   DOI: 10.1158/0008-5472.CAN-15-2998
10017  Tanaka S, Maekawa A, Matsubara L, Imanishi A, Yano M, Roeder RG, Hasegawa N, Asano S, Ito M.  Periostin supports hematopoietic progenitor cells and niche-dependent myeloblastoma cells in vitro.  Biochem. Biophys. Res. Commun.  2016  478:1706-12  PubMed ID: 27596966   DOI: 10.1016/j.bbrc.2016.09.008
4000  Okada A, Tashiro K, Yamaguchi T, Kawabata K.  Selective Differentiation into Hematopoietic and Cardiac Cells from Pluripotent Stem Cells Based on the Expression of Cell Surface Markers.  Methods Mol Biol  2016  1341:181-95  PubMed ID: 26138986   DOI: 10.1007/7651_2015_232
14111  Mohtashami M, Zarin P, Zúñiga-Pflücker JC.  Induction of T Cell Development In Vitro by Delta-Like (Dll)-Expressing Stromal Cells  Methods Mol Biol  2016  1323:159-67  PubMed ID: 26294407   DOI: 10.1007/978-1-4939-2809-5_14
7479  Kato S, Kato Y, Shibata H, Saitoh Y, Miwa N.  Repressive effects of oat extracts on intracellular lipid-droplet formation in adipocytes and a three-dimensional subcutaneous adipose tissue model.  Mater Sci Eng C Mater Biol Appl  2015  49:269-73  PubMed ID: 25686949   DOI: 10.1016/j.msec.2015.01.015
7573  Yoshimitsu M, Higuchi K, Arima N, Medin JA, Takenaka T  Successful Induction of Pluripotent Stem Cells From a Fabry Disease Mouse Model: Toward the Development of Safe Lentiviral Gene Therapy.  J Stem Cell Res Ther  2015  5:1000259    DOI: 10.4172/2157-7633.1000259
3948  Tashiro K, Hirata N, Okada A, Yamaguchi T, Takayama K, Mizuguchi H, Kawabata K.  Expression of coxsackievirus and adenovirus receptor separates hematopoietic and cardiac progenitor cells in fetal liver kinase 1-expressing mesoderm.  Stem Cells Transl Med  2015  4(5):424-36  PubMed ID: 25762001   DOI: 10.5966/sctm.2014-0173
12097  K Sakashita, I Kato, T Daifu, S Saida, H Hiramatsu, Y Nishinaka, Y Ebihara, F Ma, K Matsuda, S Saito, K Hirabayashi, T Kurata, L T N Uyen, Y Nakazawa, K Tsuji, T Heike, T Nakahata, K Koike  In vitro expansion of CD34(+)CD38(-) cells under stimulation with hematopoietic growth factors on AGM-S3 cells in juvenile myelomonocytic leukemia  Leukemia  2015  29(3):606-14  PubMed ID: 25102944   DOI: 10.1038/leu.2014.239
14461  Antony-Debré I, Manchev VT, Balayn N, Bluteau D, Tomowiak C, Legrand C, Langlois T, Bawa O, Tosca L, Tachdjian G, Leheup B, Debili N, Plo I, Mills JA, French DL, Weiss MJ, Solary E, Favier R, Vainchenker W, Raslova H.  Level of RUNX1 activity is critical for leukemic predisposition but not for thrombocytopenia  Blood  2015  125(6):930-40  PubMed ID: 25490895   DOI: 10.1182/blood-2014-06-585513
15133  Sasaki H, Wada H, Baghdadi M, Tsuji H, Otsuka R, Morita K, Shinohara N, Seino K.  New Immunosuppressive Cell Therapy to Prolong Survival of Induced Pluripotent Stem Cell-Derived Allografts  Transplantation  2015  99(11):2301-10  PubMed ID: 26360665   DOI: 10.1097/TP.0000000000000875
15178  Saliba J, Saint-Martin C, Di Stefano A, Lenglet G, Marty C, Keren B, Pasquier F, Valle VD, Secardin L, Leroy G, Mahfoudhi E, Grosjean S, Droin N, Diop M, Dessen P, Charrier S, Palazzo A, Merlevede J, Meniane JC, Delaunay-Darivon C, Fuseau P, Isnard F, Casadevall N, Solary E, Debili N, Bernard OA, Raslova H, Najman A, Vainchenker W, Bellanné-Chantelot C, Plo I.  Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies  Nat Genet  2015  47(10):1131-40  PubMed ID: 26280900   DOI: 10.1038/ng.3380
15435  Mancini SJ, Elantak L, Boned A, Espéli M, Guerlesquin F, Schiff C.  Examination of galectin-induced lattice formation on early B-cell development  Methods Mol Biol  2015  1207:169-84  PubMed ID: 25253140   DOI: 10.1007/978-1-4939-1396-1_11
5454  Kudo H, Wada H, Sasaki H, Tsuji H, Otsuka R, Baghdadi M, Kojo S, Chikaraishi T, Seino K.  Induction of macrophage-like immunosuppressive cells from mouse ES cells that contribute to prolong allogeneic graft survival.  PLoS One.  2014  9(10):e111826  PubMed ID: 25356669   DOI: 10.1371/journal.pone.0111826
6066  Awong G, Zúñiga-Pflücker JC.  Generation, isolation, and engraftment of in vitro-derived human T cell progenitors.  Methods Mol Biol  2013  946:103-13  PubMed ID: 23179828   DOI: 10.1007/978-1-62703-128-8_7
6084  Kato S, Saitoh Y, Miwa N.  Repressive effects of a capacitive-resistive electric transfer (CRet) hyperthermic apparatus combined with provitamin C on intracellular lipid-droplets formation in adipocytes.  Int J Hyperthermia  2013  29(1):30-7  PubMed ID: 23286696   DOI: 10.3109/02656736.2012.750016
9011  Ryo Kurita, Noriko Suda, Kazuhiro Sudo, Kenichi Miharada, Takashi Hiroyama, Hiroyuki Miyoshi, Kenzaburo Tani, Yukio Nakamura  Establishment of Immortalized Human Erythroid Progenitor Cell Lines Able to Produce Enucleated Red Blood Cells  PLoS One  2013  8 (3), e59890  PubMed ID: 23533656   DOI: 10.1371/journal.pone.0059890
9363  Ruri Ishino, Kaori Minami, Satowa Tanaka, Mami Nagai, Keiji Matsui, Natsumi Hasegawa, Robert G Roeder, Shigetaka Asano, Mitsuhiro Ito  FGF7 Supports Hematopoietic Stem and Progenitor Cells and Niche-Dependent Myeloblastoma Cells via Autocrine Action on Bone Marrow Stromal Cells in Vitro  Biochem Biophys Res Commun  2013  440(1):125-31  PubMed ID: 24051090   DOI: 10.1016/j.bbrc.2013.09.044
13963  Mohtashami M, Shah DK, Kianizad K, Awong G, Zúñiga-Pflücker JC.  Induction of T-cell development by Delta-like 4-expressing fibroblasts  Int Immunol   2013  25(10):601-11  PubMed ID: 23988616   DOI: 10.1093/intimm/dxt027
15783  Takeishi S, Matsumoto A, Onoyama I, Naka K, Hirao A, Nakayama KI.  Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence  Cancer Cell  2013  ;23(3):347-61  PubMed ID: 23518349   DOI: 10.1016/j.ccr.2013.01.026
15784  Liang HC, Holmes R, Zúñiga-Pflücker JC.  Directed differentiation of embryonic stem cells to the T-lymphocyte lineage  Methods Mol Biol   2013  1029:119-28  PubMed ID: 23756946   DOI: 10.1007/978-1-62703-478-4_9
15935  otake D, Hirasawa N.  Activation of a retinoic acid receptor pathway by thiazolidinediones induces production of vascular endothelial growth factor/vascular permeability factor in OP9 adipocytes  Eur J Pharmacol  2013  707(1-3):95-103  PubMed ID: 23542713   DOI: 10.1016/j.ejphar.2013.03.033
16882  Nishimura T, Hatoya S, Kanegi R, Sugiura K, Wijewardana V, Kuwamura M, Tanaka M, Yamate J, Izawa T, Takahashi M, Kawate N, Tamada H, Imai H, Inaba T.  Generation of functional platelets from canine induced pluripotent stem cells  Stem Cells Dev  2013  22(14):2026-35  PubMed ID: 23409943   DOI: 10.1089/scd.2012.0701
9142  Divya K Shah, Mahmood Mohtashami, Juan Carlos Zúñiga-Pflücker  Role of Recycling, Mindbomb1 Association, and Exclusion From Lipid Rafts of δ-Like 4 for Effective Notch Signaling to Drive T Cell Development  J Immunol  2012  189 (12), 5797-808  PubMed ID: 23162128   DOI: 10.4049/jimmunol.1202469
8040  Nishimura K, Sano M, Ohtaka M, Furuta B, Umemura Y, Nakajima Y, Ikehara Y, Kobayashi T, Segawa H, Takayasu S, Sato H, Motomura K, Uchida E, Kanayasu-Toyoda T, Asashima M, Nakauchi H, Yamaguchi T, Nakanishi M.  Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming.  J. Biol. Chem.  2011  286:4760-71  PubMed ID: 21138846   DOI: 10.1074/jbc.M110.183780
18577  Tsuzuki S, Taguchi O, Seto M.  Promotion and maintenance of leukemia by ERG  Blood  2011  117(14):3858-68.  PubMed ID: 21321361   DOI: 10.1182/blood-2010-11-320515
8154  Sumitomo A, Ishino R, Urahama N, Inoue K, Yonezawa K, Hasegawa N, Horie O, Matsuoka H, Kondo T, Roeder RG, Ito M.  The transcriptional mediator subunit MED1/TRAP220 in stromal cells is involved in hematopoietic stem/progenitor cell support through osteopontin expression.  Mol. Cell. Biol.  2010  30:4818-27  PubMed ID: 20713445   DOI: 10.1128/MCB.01348-09
8233  Mohtashami M, Shah DK, Nakase H, Kianizad K, Petrie HT, Zuniga-Pflucker JC.  Direct comparison of Dll1- and Dll4-mediated Notch activation levels shows differential lymphomyeloid lineage commitment outcomes.  J. Immunol.  2010  185:867-76  PubMed ID: 20548034   DOI: 10.4049/jimmunol.1000782
8250  Xiao L, Aoshima H, Saitoh Y, Miwa N.  The effect of squalane-dissolved fullerene-C60 on adipogenesis-accompanied oxidative stress and macrophage activation in a preadipocyte-monocyte co-culture system.  Biomaterials  2010  31:5976-85  PubMed ID: 20488530   DOI: 10.1016/j.biomaterials.2010.04.032
8423  Suzuki N, Itou T, Hasegawa Y, Okazaki T, Ikeno M.  Cell to cell transfer of the chromatin-packaged human beta-globin gene cluster.  Nucleic Acids Res.  2010  38:e33  PubMed ID: 20007595   DOI: 10.1093/nar/gkp1168
18458  Funayama K, Saito-Kurimoto Y, Ebihara Y, Shimane M, Nomura H, Tsuji K, Asano S.  Adhesion-mediated self-renewal abilities of Ph+ blastoma cells  Biochem Biophys Res Commun  2010  396(2):193-8  PubMed ID: 20362549   DOI: 10.1016/j.bbrc.2010.03.172
18561  Mace EM, Monkley SJ, Critchley DR, Takei F.  A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells  J Immunol  2009  182(2):948-56  PubMed ID: 19124737   DOI: 10.4049/jimmunol.182.2.948
6130  Holmes R, Zúñiga-Pflücker JC.  The OP9-DL1 system: generation of T-lymphocytes from embryonic or hematopoietic stem cells in vitro.  Cold Spring Harb Protoc. 2009 Feb  2009  2009(2):pdb.prot5156  PubMed ID: 20147086   DOI: 10.1101/pdb.prot5156
12195  Taro Ishigaki, Kazuhiro Sudo, Takashi Hiroyama, Kenichi Miharada, Haruhiko Ninomiya, Shigeru Chiba, Toshiro Nagasawa, Yukio Nakamura  Human hematopoietic stem cells can survive in vitro for several months  Adv Hematol  2009  2009:936761  PubMed ID: 19960048   DOI: 10.1155/2009/936761
18322  Wakao H, Wakao R, Sakata S, Iwabuchi K, Oda A, Fujita H.  In vitro induction of natural killer T cells from embryonic stem cells prepared using somatic cell nuclear transfer  FASEB J  2008  22(7):2223-31  PubMed ID: 18323403   DOI: 10.1096/fj.07-104687
8722  Nagao K, Ohta T, Hinohara A, Tahara T, Hagiwara T, Maeda Y, Yoneya T, Sohma Y, Heike T, Nakahata T, Inagaki Y, Nishikawa M.  Expression profile analysis of aorta-gonad-mesonephros region-derived stromal cells reveals genes that regulate hematopoiesis.  Biochem. Biophys. Res. Commun.  2008  377:205-9  PubMed ID: 18840400   DOI: 10.1016/j.bbrc.2008.09.123
6137  Awong G1, La Motte-Mohs RN, Zúñiga-Pflücker JC.  In vitro human T cell development directed by notch-ligand interactions.  Methods Mol Biol  2008  430:135-42  PubMed ID: 18370296   DOI: 10.1007/978-1-59745-182-6_9
7645  Shimizu N, Noda S, Katayama K, Ichikawa H, Kodama H, Miyoshi H.  Identification of genes potentially involved in supporting hematopoietic stem cell activity of stromal cell line MC3T3-G2/PA6.  Int J Hematol  2008  87(3):239-45  PubMed ID: 18317883   DOI: 10.1007/s12185-008-0048-9
10372  Hiroyama T, Miharada K, Sudo K, Danjo I, Aoki N, Nakamura Y.  Establishment of mouse embryonic stem cell-derived erythroid progenitor cell lines able to produce functional red blood cells.  PLoS ONE  2008  3(2):e1544  PubMed ID: 18253492   DOI: 10.1371/journal.pone.0001544
5989  Tanaka Y, Era T, Nishikawa S, Kawamata S.  Forced expression of Nanog in hematopoietic stem cells results in a gammadeltaT-cell disorder.  Blood  2007  110(1):107-15  PubMed ID: 17360937   DOI: 10.1182/blood-2006-08-039628
7385  Murakami Y, Hirata H, Miyamoto Y, Nagahashi A, Sawa Y, Jakt M, Asahara T, Kawamata S.  Isolation of cardiac cells from E8.5 yolk sac by ALCAM (CD166) expression.  Mech Dev  2007  124(11-12):830-9  PubMed ID: 17964124   DOI: 10.1016/j.mod.2007.09.004
8591  Hirokazu Hirata, Shin Kawamata, Yoshinobu Murakami, Kayoko Inoue, Ayako Nagahashi, Mako Tosaka, Naoko Yoshimura, Yoshiaki Miyamoto, Hiroto Iwasaki, Takayuki Asahara, Yoshiki Sawa  Coexpression of Platelet-Derived Growth Factor Receptor Alpha and Fetal Liver Kinase 1 Enhances Cardiogenic Potential in Embryonic Stem Cell Differentiation in Vitro  J Biosci Bioeng  2007  103 (5), 412-9  PubMed ID: 17609155   DOI: 10.1263/jbb.103.412
10362  Nooshin Tabatabaei-Zavareh, Anastasia Vlasova, Chelsea Pamela Greenwood, Fumio Takei  Characterization of Developmental Pathway of Natural Killer Cells From Embryonic Stem Cells in Vitro  PLoS One  2007  2(2):e232  PubMed ID: 17311098   DOI: 10.1371/journal.pone.0000232
3411  de Pooter, Renee F, Schmitt, Thomas M, de la Pompa, Jose Luis, Fujiwara, Yuko, Orkin, Stuart H, Zuniga-Pflucker, Juan Carlos  Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors.  J Immunol  2006  176:5267-75  PubMed ID: 16621992   DOI: 10.4049/jimmunol.176.9.5267
3357  Hiroyama, Takashi, Miharada, Kenichi, Aoki, Naoko, Fujioka, Tsuyoshi, Sudo, Kazuhiro, Danjo, Inaho, Nagasawa, Toshiro, Nakamura, Yukio  Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells.  Exp Hematol  2006  34:760-9  PubMed ID: 16728281   DOI: 10.1016/j.exphem.2006.03.004
3358  Takayanagi, Shin-ichiro, Hiroyama, Takashi, Yamazaki, Satoshi, Nakajima, Tomoko, Morita, Yohei, Usui, Joichi, Eto, Koji, Motohashi, Tsutomu, Shiomi, Kensuke, Keino-Masu, Kazuko, Masu, Masayuki, Oike, Yuichi, Mori, Shigeo, Yoshida, Nobuaki, Iwama, Atsushi, Nakauchi, Hiromitsu  Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell-surface protein with the thrombospondin-1 domain.  Blood  2006  107:4317-25  PubMed ID: 16455951   DOI: 10.1182/blood-2005-09-3747
6984  Takahashi M, Haruta M.  Derivation and characterization of lentoid bodies and retinal pigment epithelial cells from monkey embryonic stem cells in vitro.  Methods Mol Biol  2006  330:417-29  PubMed ID: 16846040   DOI: 10.1385/1-59745-036-7:417
3171  Niida, Shumpei, Kondo, Takako, Hiratsuka, Sachie, Hayashi, Shin-Ichi, Amizuka, Norio, Noda, Tetsuo, Ikeda, Kyoji, Shibuya, Masabumi  VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice.  Proc Natl Acad Sci U S A  2005  102:14016-21  PubMed ID: 16172397   DOI: 10.1073/pnas.0503544102
15608  de Pooter RF, Cho SK, Zúñiga-Pflücker JC.  In vitro generation of lymphocytes from embryonic stem cells  Methods Mol Biol  2005  290:135-47  PubMed ID: 15361660   DOI: 10.1385/1-59259-838-2:135
2666  Kawamura, Toshihiko, Koka, Rima, Ma, Averil, Kumar, Vinay  Differential roles for IL-15R alpha-chain in NK cell development and Ly-49 induction.  J Immunol  2003  171:5085-90  PubMed ID: 14607906   DOI: 10.4049/jimmunol.171.10.5085
12264  Shintaro Yamazaki, Kenji Miki, Kiyoshi Hasegawa, Masataka Sata, Tadatoshi Takayama, Masatoshi Makuuchi  Sera from liver failure patients and a demethylating agent stimulate transdifferentiation of murine bone marrow cells into hepatocytes in coculture with nonparenchymal liver cells  J Hepatol  2003  39(1):17-23  PubMed ID: 12821039   DOI: 10.1016/s0168-8278(03)00150-8
2428  Okada S, Yoshida T, Hong Z, Ishii G, Hatano M, Kuro-O M, Nabeshima Y, Nabeshima Y, Tokuhisa T  Impairment of B lymphopoiesis in precocious aging (klotho) mice.  Int Immunol  2000  12:861-71  PubMed ID: 10837414   DOI: 10.1093/intimm/12.6.861
9954  Morgan BJ, Crabtree D, Skatrud JB.  Chemoreflex sensitization augments sympathetic vasomotor outflow in awake humans.  Adv. Exp. Med. Biol.  1994  360:269-71  PubMed ID: 7872100   DOI: 10.1007/978-1-4615-2572-1_44



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