| 利用者成果(英) |
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19584
Kondo N, Takada S, Hagimori M, Temma T.
Development of a 2-(2-Hydroxyphenyl)-1 H-benzimidazole-Based Fluorescence Sensor Targeting Boronic Acids for Versatile Application in Boron Neutron Capture Therapy
Cancers (Basel)
2023
15(6):1862
PubMed ID: 36980747
DOI: 10.3390/cancers15061862
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19685
Sakabe N, Maruyama S, Ito C, Shimoyama Y, Komene T, Oboshi W, Sato S, Sudo K, Ikeda K.
Immunocytochemical Reactivity Comparison between Formalin-Fixed and Liquid-Based Cytology-Fixed Specimens
Acta Cytol
2023
67(1):38-45
PubMed ID: 36228592
DOI: 10.1159/000526131
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19807
Shichi Y, Gomi F, Hasegawa Y, Nonaka K, Shinji S, Takahashi K, Ishiwata T.
Artificial intelligence-based analysis of time-lapse images of sphere formation and process of plate adhesion and spread of pancreatic cancer cells
Front Cell Dev Biol
2023
11:1290753
PubMed ID: 38046666
DOI: 10.3389/fcell.2023.1290753
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19924
Yoo HB, Moon JW, Kim HR, Lee HS, Miyabayashi K, Park CH, Ge S, Zhang A, Tae YK, Sub Y, Park HW, Gee HY, Notta F, Tuveson DA, Bang S, Kim MY, Roe JS.
A TEAD2-Driven Endothelial-Like Program Shapes Basal-Like Differentiation and Metastasis of Pancreatic Cancer
Gastroenterology
2023
165(1):133-148.e17
PubMed ID: 36907523
DOI: 10.1053/j.gastro.2023.02.049
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21264
Sakabe N, Maruyama S, Ito C, Shimoyama Y, Sudo K, Sato S, Ikeda K.
Effect of liquid-based cytology fixing solution on immunocytochemistry: Efficacy of antigen retrieval in cytologic specimens.
Diagn Cytopathol
2023
PubMed ID: 37329327
DOI: 10.1002/dc.25178
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21476
Hirano F, Kondo N, Murata Y, Sudani A, Temma T.
Assessing the effectiveness of fluorinated and α-methylated 3-boronophenylalanine for improved tumor-specific boron delivery in boron neutron capture therapy.
Bioorg Chem
2023
142:106940
PubMed ID: 37939508
DOI: 10.1016/j.bioorg.2023.106940
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17663
Kondo N, Aoki E, Takada S, Temma T.
A Red-Emitting Fluorescence Sensor for Detecting Boronic Acid-Containing Agents in Cells
Sensors (Basel)
2022
22(19):7671
PubMed ID: 36236770
DOI: 10.3390/s22197671
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18221
Shichi Y, Gomi F, Sasaki N, Nonaka K, Arai T, Ishiwata T.
Epithelial and Mesenchymal Features of Pancreatic Ductal Adenocarcinoma Cell Lines in Two- and Three-Dimensional Cultures
J Pers Med
2022
12(5):746
PubMed ID: 35629168
DOI: 10.3390/jpm12050746
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18227
Chen Y, Yang S, Tavormina J, Tampe D, Zeisberg M, Wang H, Mahadevan KK, Wu CJ, Sugimoto H, Chang CC, Jenq RR, McAndrews KM, Kalluri R.
Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
Cancer Cell
2022
40(8):818-834.e9
PubMed ID: 35868307
DOI: 10.1016/j.ccell.2022.06.011
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20712
Kondo N, Hirano F, Temma T.
Evaluation of 3-Borono-l-Phenylalanine as a Water-Soluble Boron Neutron Capture Therapy Agent.
Pharmaceutics
2022
14(5)
PubMed ID: 35631692
DOI: 10.3390/pharmaceutics14051106
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20090
Minami F, Sasaki N, Shichi Y, Gomi F, Michishita M, Ohkusu-Tsukada K, Toyoda M, Takahashi K, Ishiwata T.
Morphofunctional analysis of human pancreatic cancer cell lines in 2- and 3-dimensional cultures.
Sci Rep
2021
11(1):6775
PubMed ID: 33762591
DOI: 10.1038/s41598-021-86028-1
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12080
Nishigaki T, Takahashi T, Serada S, Fujimoto M, Ohkawara T, Hara H, Sugase T, Otsuru T, Saito Y, Tsujii S, Nomura T, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Nakajima K, Eguchi H, Yamasaki M, Mori M, Doki Y, Naka T.
Anti-glypican-1 antibody-drug conjugate is a potential therapy against pancreatic cancer.
Br. J. Cancer
2020
PubMed ID: 32152502
DOI: 10.1038/s41416-020-0781-2
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13287
Sasaki N, Gomi F, Yoshimura H, Yamamoto M, Matsuda Y, Michishita M, Hatakeyama H, Kawano Y, Toyoda M, Korc M, Ishiwata T.
FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer.
Cancers (Basel)
2020
PubMed ID: 33066597
DOI: 10.3390/cancers12102976
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14280
Hobbs GA, Baker NM, Miermont AM, Thurman RD, Pierobon M, Tran TH, Anderson AO, Waters AM, Diehl JN, Papke B, Hodge RG, Klomp JE, Goodwin CM, DeLiberty JM, Wang J, Ng RWS, Gautam P, Bryant KL, Esposito D, Campbell SL, Petricoin EF 3rd, Simanshu DK, Aguirre AJ, Wolpin BM, Wennerberg K, Rudloff U, Cox AD, Der CJ.
Atypical KRAS G12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
Cancer Discov
2020
10(1):104-123
PubMed ID: 31649109
DOI: 10.1158/2159-8290.CD-19-1006
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11646
Shichi Y, Sasaki N, Michishita M, Hasegawa F, Matsuda Y, Arai T, Gomi F, Aida J, Takubo K, Toyoda M, Yoshimura H, Takahashi K, Ishiwata T.
Enhanced morphological and functional differences of pancreatic cancer with epithelial or mesenchymal characteristics in 3D culture.
Sci Rep
2019
PubMed ID: 31350453
DOI: 10.1038/s41598-019-47416-w
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11960
Sasaki N, Hirabayashi K, Michishita M, Takahashi K, Hasegawa F, Gomi F, Itakura Y, Nakamura N, Toyoda M, Ishiwata T.
Ganglioside GM2, highly expressed in the MIA PaCa-2 pancreatic ductal adenocarcinoma cell line, is correlated with growth, invasion, and advanced stage.
Sci Rep
2019
PubMed ID: 31852956
DOI: 10.1038/s41598-019-55867-4
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14277
Liu S, Hausmann S, Carlson SM, Fuentes ME, Francis JW, Pillai R, Lofgren SM, Hulea L, Tandoc K, Lu J, Li A, Nguyen ND, Caporicci M, Kim MP, Maitra A, Wang H, Wistuba II, Porco JA Jr, Bassik MC, Elias JE, Song J, Topisirovic I, Van Rechem C, Mazur PK, Gozani O.
METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis
Cell
2019
176(3):491-504.e21
PubMed ID: 30612740
DOI: 10.1016/j.cell.2018.11.038
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4544
Kamerkar S, LeBleu VS, Sugimoto H, Yang S, Ruivo CF, Melo SA, Lee JJ, Kalluri R.
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.
Nature
2017
546(7659):498-503
PubMed ID: 28607485
DOI: 10.1038/nature22341
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14928
Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R.
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
Nature
2015
523(7559):177-82
PubMed ID: 26106858
DOI: 10.1038/nature14581
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5590
Wongthai P, Hagiwara K, Miyoshi Y, Wiriyasermkul P, Wei L, Ohgaki R, Kato I, Hamase K, Nagamori S, Kanai Y.
Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2
Cancer Sci
2015
106(3):279-86
PubMed ID: 25580517
DOI: 10.1111/cas.12602
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18173
Kahlert C, Melo SA, Protopopov A, Tang J, Seth S, Koch M, Zhang J, Weitz J, Chin L, Futreal A, Kalluri R.
Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer
J Biol Chem
2014
289(7):3869-75
PubMed ID: 24398677
DOI: 10.1074/jbc.C113.532267
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7761
Kahlert C, Bergmann F, Beck J, Welsch T, Mogler C, Herpel E, Dutta S, Niemietz T, Koch M, Weitz J.
Low expression of aldehyde dehydrogenase 1A1 (ALDH1A1) is a prognostic marker for poor survival in pancreatic cancer.
BMC Cancer
2011
11:275
PubMed ID: 21708005
DOI: 10.1186/1471-2407-11-275
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5877
Yamamoto H, Okumura K, Toshima S, Mukaisho K, Sugihara H, Hattori T, Kato M, Asano S.
FXYD3 protein involved in tumor cell proliferation is overproduced in human breast cancer tissues.
Biol Pharm Bull
2009
32(7):1148-54
PubMed ID: 19571376
DOI: 10.1248/bpb.32.1148
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3717
Wada M, Yazumi S, Takaishi S, Hasegawa K, Sawada M, Tanaka H, Ida H, Sakakura C, Ito K, Ito Y, Chiba T.
Frequent loss of RUNX3 gene expression in human bile duct and pancreatic cancer cell lines.
Oncogene
2004
23(13):2401-7
PubMed ID: 14743205
DOI: 10.1038/sj.onc.1207395
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