Cell No. : Cell Name
RCB1006 : KP4-1
update : 2024/11/12
|
| Comment | Pancreatic ductal cell carcinoma. PTHrP producing. |
| Comment from the depositor | |
| Terms and conditions | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
| Remarks | |
| Order Form |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
|
|
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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Basic information
|
Depositor |
Nishi, Y. & Nawata, H.
|
| Originator |
Nawata, H. & Nishi, Y.
|
| Year of deposit |
1994
|
| Another name |
KP4-1(Cl-4)
|
| Original cell |
KP4
|
| Animal |
_human
< Mammals
|
| Genus |
Homo
|
| Species |
sapiens
|
| Race |
Japanese
|
| Gender |
Male
|
| Age at sampling |
50 years
|
| Tissue |
pancreas, ascites meta
|
| Disease name |
pancreatic ductal cell carcino
|
| Metastatic ability |
Yes
|
| Metastatic tissue |
liver, lung, etc.
|
| Classification |
cancer
|
| Year of origin |
1990
|
| History |
Direct from originator.
|
| Memo_1 |
Mycoplasma was eliminated with MC-210 by the depositor.
|
|
Lifespan |
infinite
|
| Morphology |
epithelial-like
|
| Cellosaurus(Expasy) |
CVCL_8727
|
|
| |
deposit info |
lot info |
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Medium |
Medium List |
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Culture type |
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Adherent cells
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| Culture medium |
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DMEM/HamF12 + 10% FBS
|
| Antibiotics |
|
Free
|
|
Passage method |
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0.25% Trypsin
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Culture information
|
Passage ratio |
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1 : 8 split
|
| SC frequency |
|
Subculture : 2 times/week
|
| Temperature |
|
37
℃
|
| CO2 concentration |
|
5
%
|
| Freeze medium |
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Medium + 10% DMSO
|
| Freezing method |
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Slow freezing
|
| Mycoplasma/Acholeplasma |
|
(-)
|
| Isozyme |
|
LD, NP
|
| Chromosome mode |
|
65-71(50) : 65(3),66(12),67(10),68(9),70(5),71(2)/
|
| STR(human) |
|
OK
|
| Images |
deposit info | lot info |
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| Reference information |
Reference |
1
|
| User's Publication |
9
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| User's Publication |
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20773
Han JH, Kim YK, Kim H, Lee J, Oh MJ, Kim SB, Kim M, Kim KH, Yoon HJ, Lee MS, Minna JD, White MA, Kim HS.
Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells.
Cancer Commun (Lond)
2022
PubMed ID: 35838183
DOI: 10.1002/cac2.12332
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20431
Shiozaki A, Konishi T, Kosuga T, Kudou M, Kurashima K, Inoue H, Shoda K, Arita T, Konishi H, Morimura R, Komatsu S, Ikoma H, Toma A, Kubota T, Fujiwara H, Okamoto K, Otsuji E.
Roles of voltage‑gated potassium channels in the maintenance of pancreatic cancer stem cells.
Int J Oncol
2021
59(4)
PubMed ID: 34414448
DOI: 10.3892/ijo.2021.5256
|
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14726
Imamura T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Ohashi T, Kiuchi J, Nishibeppu K, Konishi H, Shiozaki A, Morimura R, Ikoma H, Ochiai T, Okamoto K, Taniguchi H, Otsuji E.
Depleted tumor suppressor miR-107 in plasma relates to tumor progression and is a novel therapeutic target in pancreatic cancer
Sci Rep
2017
7(1):5708
PubMed ID: 28720759
DOI: 10.1038/s41598-017-06137-8
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9592
Hijiya N, Tsukamoto Y, Nakada C, Tung Nguyen L, Kai T, Matsuura K, Shibata K, Inomata M, Uchida T, Tokunaga A, Amada K, Shirao K, Yamada Y, Mori H, Takeuchi I, Seto M, Aoki M, Takekawa M, Moriyama M.
Genomic Loss of DUSP4 Contributes to the Progression of Intraepithelial Neoplasm of Pancreas to Invasive Carcinoma.
Cancer Res.
2016
76:2612-25
PubMed ID: 26941286
DOI: 10.1158/0008-5472.CAN-15-1846
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7168
Miyamae M, Komatsu S, Ichikawa D, Kawaguchi T, Hirajima S, Okajima W, Ohashi T, Imamura T, Konishi H, Shiozaki A, Morimura R, Ikoma H, Ochiai T, Okamoto K, Taniguchi H, Otsuji E.
Plasma microRNA profiles: identification of miR-744 as a novel diagnostic and prognostic biomarker in pancreatic cancer.
Br. J. Cancer
2015
113:1467-76
PubMed ID: 26505678
DOI: 10.1038/bjc.2015.366
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5024
Kawaguchi T, Komatsu S, Ichikawa D, Morimura R, Tsujiura M, Konishi H, Takeshita H, Nagata H, Arita T, Hirajima S, Shiozaki A, Ikoma H, Okamoto K, Ochiai T, Taniguchi H, Otsuji E.
Clinical impact of circulating miR-221 in plasma of patients with pancreatic cancer.
Br J Cancer
2013
108(2):361-9
PubMed ID: 23329235
DOI: 10.1038/bjc.2012.546
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5032
Igarashi S, Matsubara T, Harada K, Ikeda H, Sato Y, Sasaki M, Matsui O, Nakanuma Y.
Bile duct expression of pancreatic and duodenal homeobox 1 in perihilar cholangiocarcinogenesis.
Histopathology
2012
61(2):266-76
PubMed ID: 22594685
DOI: 10.1111/j.1365-2559.2012.04218.x
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7643
Morimura R, Komatsu S, Ichikawa D, Takeshita H, Tsujiura M, Nagata H, Konishi H, Shiozaki A, Ikoma H, Okamoto K, Ochiai T, Taniguchi H, Otsuji E.
Novel diagnostic value of circulating miR-18a in plasma of patients with pancreatic cancer.
Br. J. Cancer
2011
105:1733-40
PubMed ID: 22045190
DOI: 10.1038/bjc.2011.453
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3717
Wada M, Yazumi S, Takaishi S, Hasegawa K, Sawada M, Tanaka H, Ida H, Sakakura C, Ito K, Ito Y, Chiba T.
Frequent loss of RUNX3 gene expression in human bile duct and pancreatic cancer cell lines.
Oncogene
2004
23(13):2401-7
PubMed ID: 14743205
DOI: 10.1038/sj.onc.1207395
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