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13647
Hikita K, Yamakage Y, Okunaga H, Motoyama Y, Matsuyama H, Matsuoka K, Murata T, Nakayoshi T, Oda A, Kato K, Tanaka H, Asao N, Dan S, Kaneda N.
(S)-Erypoegin K, an isoflavone isolated from Erythrina poeppigiana, is a novel inhibitor of topoisomerase IIα: Induction of G2 phase arrest in human gastric cancer cells
Bioorg Med Chem
2021
30:115904.
PubMed ID: 33341500
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12039
Kim JH, Park S, Lim SM, Eom HJ, Balch C, Lee J, Kim GJ, Jeong JH, Nam S, Kim YH.
Rational design of small molecule RHOA inhibitors for gastric cancer.
Pharmacogenomics J.
2020
PubMed ID: 32015453
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13242
Uejima C, Morimoto M, Yamamoto M, Hara K, Miyauchi W, Sugezawa K, Tada Y, Tanio A, Kihara K, Matsunaga T, Tokuyasu N, Sakamoto T, Honjo S, Umekita Y, Fujiwara Y.
Prognostic Significance of TYRO3 Receptor Tyrosine Kinase Expression in Gastric Cancer.
Anticancer Res
2020
40(10):5593-5600
PubMed ID: 32988883
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13315
Ebert K, Zwingenberger G, Barbaria E, Keller S, Heck C, Arnold R, Hollerieth V, Mattes J, Geffers R, Raimúndez E, Hasenauer J, Luber B.
Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines.
BMC Cancer
2020
PubMed ID: 33115415
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13337
Kim S, Ahn JM, Bae WJ, Han JH, Lee D.
Quantitation of ligand is critical for ligand-dependent MET signalling activation and determines MET-targeted therapeutic response in gastric cancer.
Gastric Cancer
2020
PubMed ID: 33164142
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13600
Sano H, Futamura M, Gaowa S, Kamino H, Nakamura Y, Yamaguchi K, Tanaka Y, Yasufuku I, Nakakami A, Arakawa H, Yoshida K.
p53/Mieap-regulated mitochondrial quality control plays an important role as a tumor suppressor in gastric and esophageal cancers
Biochem Biophys Res Commun
2020
529(3):582-589.
PubMed ID: 32736677
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11505
Kageyama-Yahara N, Yamamichi N, Takahashi Y, Takeuchi C, Matsumoto Y, Sakaguchi Y, Koike K.
Tandem repeats of the 5' flanking region of human MUC5AC have a role as a novel enhancer in MUC5AC gene expression.
Biochem Biophys Rep
2019
18:100632
PubMed ID: 30993217
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11511
Behan FM, Iorio F, Picco G, Gonçalves E, Beaver CM, Migliardi G, Santos R, Rao Y, Sassi F, Pinnelli M, Ansari R, Harper S, Jackson DA, McRae R, Pooley R, Wilkinson P, van der Meer D, Dow D, Buser-Doepner C, Bertotti A, Trusolino L, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ.
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature
2019
PubMed ID: 30971826
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11819
Moro H, Hattori N, Nakamura Y, Kimura K, Imai T, Maeda M, Yashiro M, Ushijima T.
Epigenetic priming sensitizes gastric cancer cells to irinotecan and cisplatin by restoring multiple pathways.
Gastric Cancer
2019
PubMed ID: 31555951
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11499
S Zhang et al
Sensitization of Gastric Cancer Cells to Irinotecan by p53 Activation
BPB Reports
2019
2,130-133
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10766
Devanand P, Oya Y, Sundaramoorthy S, Song KY, Watanabe T, Kobayashi Y, Shimizu Y, Hong SA, Suganuma M, Lim IK.
Inhibition of TNFα-interacting protein α (Tipα)-associated gastric carcinogenesis by BTG2/TIS21 via downregulating cytoplasmic nucleolin expression.
Exp. Mol. Med.
2018
50:e449
PubMed ID: 29472702
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11231
Wang Z, Qu H, Gong W, Liu A.
Up-regulation and tumor-promoting role of SPHK1 were attenuated by miR-330-3p in gastric cancer.
IUBMB Life
2018
PubMed ID: 30281914
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11282
Sekino N, Kano M, Matsumoto Y, Sakata H, Murakami K, Toyozumi T, Otsuka R, Yokoyama M, Shiraishi T, Okada K, Kamata T, Ryuzaki T, Matsubara H.
The Antitumor Effects of Metformin on Gastric Cancer In Vitro and on Peritoneal Metastasis.
Anticancer Res.
2018
PubMed ID: 30396946
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11338
Oku T, Shimada K, Kenmotsu H, Ando Y, Kurisaka C, Sano R, Tsuiji M, Hasegawa S, Fukui T, Tsuji T.
Stimulation of Peritoneal Mesothelial Cells to Secrete Matrix Metalloproteinase-9 (MMP-9) by TNF-α: A Role in the Invasion of Gastric Carcinoma Cells.
Int J Mol Sci
2018
PubMed ID: 30544870
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4425
Curcumin inhibition of the effects of Tip α induced cytokine expression in gastric cancer patients
PharmaNutrition
2018
6,100-106
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4190
Kurata A, Yamada M, Ohno SI, Inoue S, Hashimoto H, Fujita K, Takanashi M, Kuroda M.
Expression level of microRNA-200c is associated with cell morphology in vitro and histological differentiation through regulation of ZEB1/2 and E-cadherin in gastric carcinoma.
Oncol. Rep.
2018
PubMed ID: 29138864
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4300
Keller S, Zwingenberger G, Ebert K, Hasenauer J, Wasmuth J, Maier D, Haffner I, Schierle K, Weirich G, Luber B.
Effects of trastuzumab and afatinib on kinase activity in gastric cancer cell lines.
Mol Oncol
2018
PubMed ID: 29325228
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5801
Jiao S, Guan J, Chen M, Wang W, Li C, Wang Y, Cheng Y, Zhou Z.
Targeting IRF3 as a YAP agonist therapy against gastric cancer.
J Exp Med
2018
215(2):699-718
PubMed ID: 29339449
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13126
Gaowa S, Futamura M, Tsuneki M, Kamino H, Tajima JY, Mori R, Arakawa H, Yoshida K.
Possible role of p53/Mieap-regulated mitochondrial quality control as a tumor suppressor in human breast cancer.
Cancer Sci
2018
PubMed ID: 30290054
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9788
Deguchi Y, Okabe H, Oshima N, Hisamori S, Minamiguchi S, Muto M, Sakai Y.
PTEN loss is associated with a poor response to trastuzumab in HER2-overexpressing gastroesophageal adenocarcinoma.
Gastric Cancer
2017
20:416-427
PubMed ID: 27517839
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10098
Ito C, Nishizuka SS, Ishida K, Uesugi N, Sugai T, Tamura G, Koeda K, Sasaki A.
Analysis of PIK3CA mutations and PI3K pathway proteins in advanced gastric cancer.
J. Surg. Res.
2017
212:195-204
PubMed ID: 28550907
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4550
Segatto M, Fittipaldi R, Pin F, Sartori R, Dae Ko K, Zare H, Fenizia C, Zanchettin G, Pierobon ES, Hatakeyama S, Sperti C, Merigliano S, Sandri M, Filippakopoulos P, Costelli P, Sartorelli V, Caretti G.
Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival.
Abstract
Nat Commun
2017
8(1):1707
PubMed ID: 29167426
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5804
Authors: Takashi Okuda Tomohiko Taki Kazuhiro Nishida Yoshiaki Chinen Hisao Nagoshi Chouhei Sakakura Masafumi Taniwaki
Molecular heterogeneity in the novel fusion gene APIP-FGFR2: Diversity of genomic breakpoints in gastric cancer with high-level amplifications at 11p13 and 10q26
Oncology Letters
2017
13(1):215-221
PubMed ID: 28123544
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9670
Nukuda A, Endoh H, Yasuda M, Mizutani T, Kawabata K, Haga H.
Role of ATF5 in the invasive potential of diverse human cancer cell lines.
Biochem. Biophys. Res. Commun.
2016
474:509-514
PubMed ID: 27125458
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9731
Mizutani N, Abe M, Matsuoka S, Kajino K, Wakiya M, Ohtsuji N, Hatano R, Morimoto C, Hino O.
Establishment of anti-mesothelioma monoclonal antibodies.
BMC Res Notes
2016
9:324
PubMed ID: 27342200
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5818
Feng Y et al
Hematopoietic pre-B cell leukemia transcription factor interacting protein is overexpressed in gastric cancer and promotes gastric cancer cell proliferation, migration, and invasion.
Cancer Sci
2015
106(10):1313-22
PubMed ID: 26211905
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12951
Kubo H, Kitajima Y, Kai K, Nakamura J, Miyake S, Yanagihara K, Morito K, Tanaka T, Shida M, Noshiro H.
Regulation and clinical significance of the hypoxia-induced expression of ANGPTL4 in gastric cancer
Oncol Lett
2015
11(2):1026-1034.
PubMed ID: 26893686
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5827
Ito T, Kajino K, Abe M, Sato K, Maekawa H, Sakurada M, Orita H, Wada R, Kajiyama Y, Hino O.
ERC/mesothelin is expressed in human gastric cancer tissues and cell lines.
Oncol Rep
2014
31(1):27-33
PubMed ID: 24146039
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5828
Watanabe T, Takahashi A, Suzuki K, Kurusu-Kanno M, Yamaguchi K, Fujiki H, Suganuma M.
Epithelial-mesenchymal transition in human gastric cancer cell lines induced by TNF-α-inducing protein of Helicobacter pylori.
Int J Cancer
2014
134(10):2373-82
PubMed ID: 24249671
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6398
Nagano K, Yamashita T, Inoue M, Higashisaka K, Yoshioka Y, Abe Y, Mukai Y, Kamada H, Tsutsumi Y, Tsunoda S
Eph receptor A10 has a potential as a target for a prostate cancer therapy.
Biochem Biophys Res Commun
2014
450(1):545-9
PubMed ID: 24924629
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5845
Konno-Shimizu M1, Yamamichi N, Inada K, Kageyama-Yahara N, Shiogama K, Takahashi Y, Asada-Hirayama I, Yamamichi-Nishina M, Nakayama C, Ono S, Kodashima S, Fujishiro M, Tsutsumi Y, Ichinose M, Koike K.
Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.
PLoS One
2013
8(2):e56766
PubMed ID: 23451082
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9102
Toshiaki Tsuji, Mikihito Nakamori, Makoto Iwahashi, Masaki Nakamura, Toshiyasu Ojima, Takeshi Iida, Masahiro Katsuda, Keiji Hayata, Yasushi Ino, Tomoki Todo, Hiroki Yamaue
An Armed Oncolytic Herpes Simplex Virus Expressing thrombospondin-1 Has an Enhanced in Vivo Antitumor Effect Against Human Gastric Cancer
Int J Cancer
2013
132 (2), 485-94
PubMed ID: 22729516
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7628
Kamoshida G, Matsuda A, Sekine W, Mizuno H, Oku T, Itoh S, Irimura T, Tsuji T.
Monocyte differentiation induced by co-culture with tumor cells involves RGD-dependent cell adhesion to extracellular matrix.
Cancer Lett.
2012
315:145-52
PubMed ID: 22104730
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5848
Kataoka Y, Mukohara T, Tomioka H, Funakoshi Y, Kiyota N, Fujiwara Y, Yashiro M, Hirakawa K, Hirai M, Minami H.
Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks.
Invest New Drugs
2012
30(4):1352-60
PubMed ID: 21655918
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5850
Miyato H, Tsuno NH, Kitayama J.
Semaphorin 3C is involved in the progression of gastric cancer.
Cancer Sci
2012
103(11):1961-6
PubMed ID: 22924992
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5852
Tomioka H, Mukohara T, Kataoka Y, Ekyalongo RC, Funakoshi Y, Imai Y, Kiyota N, Fujiwara Y, Minami H.
Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification.
Int J Oncol
2012
41(2):551-8
PubMed ID: 22614071
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7876
Hiraki M, Kitajima Y, Koga Y, Tanaka T, Nakamura J, Hashiguchi K, Noshiro H, Miyazaki K.
Aberrant gene methylation is a biomarker for the detection of cancer cells in peritoneal wash samples from advanced gastric cancer patients.
Ann. Surg. Oncol.
2011
18:3013-9
PubMed ID: 21409489
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8253
Seto M, Ohta M, Ikenoue T, Sugimoto T, Asaoka Y, Tada M, Mohri D, Kudo Y, Ijichi H, Tateishi K, Otsuka M, Hirata Y, Maeda S, Koike K, Omata M.
Reduced expression of RAS protein activator like-1 in gastric cancer.
Int. J. Cancer
2011
128:1293-302
PubMed ID: 20473946
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5865
Nakata W, Hayakawa Y, Nakagawa H, Sakamoto K, Kinoshita H, Takahashi R, Hirata Y, Maeda S, Koike K.
Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer.
Int J Oncol
2011
39(6):1529-36
PubMed ID: 21785822
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5866
Nakamura J, Kitajima Y, Kai K, Hashiguchi K, Hiraki M, Noshiro H, Miyazaki K.
Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer.
Am J Pathol
2011
178(2):515-24
PubMed ID: 21281785
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6115
Kakimoto T, Shiraishi R, Iwakiri R, Fujimoto K, Takahashi H, Hamajima H, Mizuta T, Ideguchi H, Toda S, Kitajima Y, Ozaki I, Matsuhashi S.
Expression patterns of the tumor suppressor PDCD4 and correlation with β-catenin expression in gastric cancers.
Oncol Rep
2011
26(6):1385-92
PubMed ID: 21894439
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8110
Ramachandran S, Shida D, Nagahashi M, Fang X, Milstien S, Takabe K, Spiegel S.
Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription.
FEBS Lett.
2010
584:4077-82
PubMed ID: 20804754
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8315
Saito Y, Sekine W, Sano R, Komatsu S, Mizuno H, Katabami K, Shimada K, Oku T, Tsuji T.
Potentiation of cell invasion and matrix metalloproteinase production by alpha3beta1 integrin-mediated adhesion of gastric carcinoma cells to laminin-5.
Clin. Exp. Metastasis
2010
27:197-205
PubMed ID: 20352300
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5868
Tsunemi S, Nakanishi T, Fujita Y, Bouras G, Miyamoto Y, Miyamoto A, Nomura E, Takubo T, Tanigawa N.
Proteomics-based identification of a tumor-associated antigen and its corresponding autoantibody in gastric cancer.
Oncol Rep
2010
23(4):949-56
PubMed ID: 20204278
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5877
Yamamoto H, Okumura K, Toshima S, Mukaisho K, Sugihara H, Hattori T, Kato M, Asano S.
FXYD3 protein involved in tumor cell proliferation is overproduced in human breast cancer tissues.
Biol Pharm Bull
2009
32(7):1148-54
PubMed ID: 19571376
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5882
Shichiri M, Fukai N, Kono Y, Tanaka Y.
Rifampicin as an oral angiogenesis inhibitor targeting hepatic cancers.
Cancer Res
2009
69(11):4760-8
PubMed ID: 19458074
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6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
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5886
Inoue M, Matsumoto S, Saito H, Tsujitani S, Ikeguchi M.
Intraperitoneal administration of a small interfering RNA targeting nuclear factor-kappa B with paclitaxel successfully prolongs the survival of xenograft model mice with peritoneal metastasis of gastric cancer.
Int J Cancer.
2008
123(11):2696-701
PubMed ID: 18798274
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12803
Lindén SK, Driessen KM, McGuckin MA.
Improved in vitro model systems for gastrointestinal infection by choice of cell line, pH, microaerobic conditions, and optimization of culture conditions
Helicobacter
2007
12(4):341-53
PubMed ID: 17669108
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5897
Kanaji S, Saito H, Tsujitani S, Matsumoto S, Tatebe S, Kondo A, Ozaki M, Ito H, Ikeguchi M.
Expression of polo-like kinase 1 (PLK1) protein predicts the survival of patients with gastric carcinoma.
Oncology
2006
70(2):126-33
PubMed ID: 16645325
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5904
Matsumoto S, Saito H, Tsujitani S, Ikeguchi M.
Allogeneic gastric cancer cell-dendritic cell hybrids induce tumor antigen (carcinoembryonic antigen) specific CD8(+) T cells.
Cancer Immunol Immunother
2006
55(2):131-9
PubMed ID: 15891883
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3167
Horie, Nobuyuki, Hirabayashi, Naomi, Takahashi, Yoshie, Miyauchi, Yuko, Taguchi, Hiroko, Takeishi, Keiichi
Synergistic effect of green tea catechins on cell growth and apoptosis induction in gastric carcinoma cells.
Biol Pharm Bull
2005
28:574-9
PubMed ID: 15802789
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5909
Matsui Y, Inomata M, Tojigamori M, Sonoda K, Shiraishi N, Kitano S.
Suppression of tumor growth in human gastric cancer with HER2 overexpression by an anti-HER2 antibody in a murine model.
Int J Oncol
2005
27(3):681-5
PubMed ID: 16077916
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5912
Nakamura M, Gabazza EC, Imoto I, Yano Y, Taguchi O, Horiki N, Fukudome K, Suzuki K, Adachi Y.
Anti-inflammatory effect of activated protein C in gastric epithelial cells.
J Thromb Haemost
2005
3(12):2721-9
PubMed ID: 16246255
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5919
Shizue Yoshioka, Shigeru Tatebe, Naruo Tokuyasu, Kenjiro Taniguchi, Yoshimi Ogami, Osamu Yamamoto, Keigo Ashida, Yoshihito Gomyo, Akira Kondo, Shunichi Tsujitani and Masahide Ikeguchi
The PI3K-Akt Pathway in SN-38-Induced Apoptosis in Human Gastric Cancer Cell Lines
Yonago Acta medica
2005
48:7–16
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6449
Yamashita Y, Nishida K, Okuda T, Nomura K, Matsumoto Y, Mitsufuji S, Horiike S, Hata H, Sakakura C, Hagiwara A, Yamagishi H, Taniwaki M.
Recurrent chromosomal rearrangements at bands 8q24 and 11q13 in gastric cancer as detected by multicolor spectral karyotyping.
World J Gastroenterol
2005
11(33):5129-35
PubMed ID: 16127741
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12834
Lu H, Wu JY, Kudo T, Ohno T, Graham DY, Yamaoka Y.
Regulation of interleukin-6 promoter activation in gastric epithelial cells infected with Helicobacter pylori
Mol Biol Cell
2005
16(10):4954-66.
PubMed ID: 16030249
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2807
Shida D, Kitayama J, Yamaguchi H, Hama K, Aoki J, Arai H, Yamashita H, Mori K, Sako A, Konishi T, Watanabe T, Sakai T, Suzuki R, Ohta H, Takuwa Y, Nagawa H
Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells.
Exp Cell Res
2004
301:168-78
PubMed ID: 15530853
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5922
Meng H, Lu C, Mabuchi H, Tanigawa N.
Prognostic significance and different properties of survivin splicing variants in gastric cancer.
Cancer Lett
2004
216(2):147-55
PubMed ID: 15533590
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5940
Chong JM, Sakuma K, Sudo M, Osawa T, Ohara E, Uozaki H, Shibahara J, Kuroiwa K, Tominaga S, Hippo Y, Aburatani H, Funata N, Fukayama M.
Interleukin-1beta expression in human gastric carcinoma with Epstein-Barr virus infection.
J Virol
2002
76(13):6825-31
PubMed ID: 12050395
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5941
Fujiwara H, Terashima M, Irinoda T, Takagane A, Abe K, Kashiwaba M, Oyama K, Takahashi M, Maesawa C, Saito K, Takechi T, Fukushima M.
Quantitative measurement of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA level in gastric cancer by real-time RT-PCR.
Jpn J Cancer Res
2002
93(12):1342-50
PubMed ID: 12495474
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3772
Ijichi H, Ikenoue T, Kato N, Mitsuno Y, Togo G, Kato J, Kanai F, Shiratori Y, Omata M.
Systematic analysis of the TGF-beta-Smad signaling pathway in gastrointestinal cancer cells.
Biochem Biophys Res Commun
2001
289(2):350-7
PubMed ID: 11716479
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5950
Sato K, Sasaki K, Akiyama Y, Yamaguchi K.
Mass spectrometric high-throughput analysis of serum-free conditioned medium from cancer cell lines.
Cancer Lett
2001
170(2):153-9
PubMed ID: 11463493
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5953
Matsumura M, Ijichi M, Shiratori Y, Togo G, Hikiba Y, Inoued K, Kohara M, Omata M.
Simple quantitative assay of alpha-fetoprotein mRNA in liver tissue using the real-time detection polymerase chain reaction assay - its application for clinical use.
Hepatol Res
2001
20(1):84-96
PubMed ID: 11282488
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5957
Senoo M, Tsuchiya I, Matsumura Y, Mori T, Saito Y, Kato H, Okamoto T, Habu S.
Transcriptional dysregulation of the p73L / p63 / p51 / p40 / KET gene in human squamous cell carcinomas: expression of Delta Np73L, a novel dominant-negative isoform, and loss of expression of the potential tumour suppressor p51.
Br J Cancer
2001
84(9):1235-41
PubMed ID: 11336476
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5958
Sakakura C, Hagiwara A, Yasuoka R, Fujita Y, Nakanishi M, Masuda K, Shimomura K, Nakamura Y, Inazawa J, Abe T, Yamagishi H.
Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation.
Br J Cancer
2001
84(6):824-31
PubMed ID: 11259099
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2194
Nishizuka S, Tamura G, Maesawa C, Sakata K, Suzuki Y, Iwaya T, Terashima M, Saito K, Satodate R
Analysis of the DPC4 gene in gastric carcinoma
Jpn J Cancer Res
1997
88:335-339
PubMed ID: 9197522
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5973
Tamura G, Sakata K, Nishizuka S, Maesawa C, Suzuki Y, Iwaya T, Terashima M, Saito K, Satodate R.
Analysis of the fragile histidine triad gene in primary gastric carcinomas and gastric carcinoma cell lines.
Genes Chromosomes Cancer
1997
20(1):98-102
PubMed ID: 9290961
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