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Targeted dynamic phospho-proteogenomic analysis of gastric cancer cells suggests host immunity provides survival benefit.
Mol Cell Proteomics
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Rg3-lipo biomimetic delivery of paclitaxel enhances targeting of tumors and myeloid-derived suppressor cells.
J Clin Invest
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Retroviral Replicating Vectors Mediated Prodrug Activator Gene Therapy in a Gastric Cancer Model
Int J Mol Sci
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19687
Mori Y, Nishikawa SG, Fratiloiu AR, Tsutsui M, Kataoka H, Joh T, Johnston RN.
Modulation of Reoviral Cytolysis (I): Combination Therapeutics
Viruses
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19939
hiozaki A, Fukami T, Shimizu H, Kosuga T, Kudou M, Takemoto K, Katsurahara K, Nishibeppu K, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Otsuji E.
Effects of TRPV2 on the Expression of PD-L1 and Its Binding Ability to PD-1 in Gastric Cancer
Ann Surg Oncol
2023
30(13):8704-8716
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19972
Eom JW, Lim JW, Kim H.
Lutein Induces Reactive Oxygen Species-Mediated Apoptosis in Gastric Cancer AGS Cells via NADPH Oxidase Activation
Molecules
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28(3):1178
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21477
Takeuchi C, Sato J, Yamamichi N, Kageyama-Yahara N, Sasaki A, Akahane T, Aoki R, Nakajima S, Ito M, Yamamichi M, Liu YY, Sakuma N, Takahashi Y, Sakaguchi Y, Tsuji Y, Sakurai K, Tomida S, Niimi K, Ushijima T, Fujishiro M.
Marked intestinal trans-differentiation by autoimmune gastritis along with ectopic pancreatic and pulmonary trans-differentiation.
J Gastroenterol
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PubMed ID: 37962678
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17567
Takashima Y, Komatsu S, Ohashi T, Kiuchi J, Kamiya H, Shimizu H, Arita T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E.
Overexpression of Tetraspanin31 contributes to malignant potential and poor outcomes in gastric cancer
Cancer Sci
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113(6):1984-1998
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18233
Zhang W, Auguste A, Liao X, Walterskirchen C, Bauer K, Lin YH, Yang L, Sayedian F, Fabits M, Bergmann M, Binder C, Corrales L, Vogt AB, Hudson LJ, Barnes MP, Bisht A, Giragossian C, Voynov V, Adam PJ, Hipp S.
A Novel B7-H6-Targeted IgG-Like T Cell-Engaging Antibody for the Treatment of Gastrointestinal Tumors
Clin Cancer Res
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28(23):5190-5201
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Iwamuro M, Shiraha H, Kobashi M, Horiguchi S, Okada H.
Laminin 511-E8 Fragment Offers Superior Adhesion Properties for Gastric Cancer Cells Compared with Full-Length Laminin 511
Curr Issues Mol Biol
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44(4):1539-1551
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20459
Kato S, Shiozaki A, Kudou M, Shimizu H, Kosuga T, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
TRPV2 Promotes Cell Migration and Invasion in Gastric Cancer via the Transforming Growth Factor-β Signaling Pathway.
Ann Surg Oncol
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Hypomethylation-activated cancer-testis gene LIN28B promotes cell proliferation and metastasis in gastric cancer.
Gene
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Yoshioka H, Kawamura T, Muroi M, Kondoh Y, Honda K, Kawatani M, Aono H, Waldmann H, Watanabe N, Osada H.
Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1)
ACS Chem Biol
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Takaki W, Konishi H, Matsubara D, Shoda K, Arita T, Kataoka S, Shibamoto J, Furuke H, Takabatake K, Shimizu H, Komatsu S, Shiozaki A, Kubota T, Okamoto K, Otsuji E.
Role of Extracellular High-Mobility Group Box-1 as a Therapeutic Target of Gastric Cancer.
Int J Mol Sci
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Ishikawa A, Kuraoka K, Zaitsu J, Saito A, Kuwai T, Tazawa H, Suzuki T, Tashiro H, Taniyama K, Yasui W.
Transcriptomic Analysis of Annexin A10 and Chemosensitivity in Gastric Adenocarcinoma Cells.
Anticancer Res
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20627
Soda T, Gen Y, Terasaki K, Iwai N, Kitaichi T, Dohi O, Taketani H, Seko Y, Umemura A, Nishikawa T, Yamaguchi K, Moriguchi M, Konishi H, Naito Y, Itoh Y, Yasui K.
Loss of KAP3 decreases intercellular adhesion and impairs intracellular transport of laminin in signet ring cell carcinoma of the stomach.
Sci Rep
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12(1):5050
PubMed ID: 35322078
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Inoue H, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
Functions and Clinical Significance of CACNA2D1 in Gastric Cancer.
Ann Surg Oncol
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ω-3 and ω-6 Polyunsaturated Fatty Acids Regulate the Proliferation, Invasion and Angiogenesis of Gastric Cancer Through COX/PGE Signaling Pathway
Front Oncol
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Sugezawa K, Morimoto M, Yamamoto M, Matsumi Y, Nakayama Y, Hara K, Uejima C, Kihara K, Matsunaga T, Tokuyasu N, Sakamoto T, Umekita Y, Fujiwara Y.
GPX4 Regulates Tumor Cell Proliferation via Suppressing Ferroptosis and Exhibits Prognostic Significance in Gastric Cancer.
Anticancer Res
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Anoctamin 5 regulates the cell cycle and affects prognosis in gastric cancer
World J Gastroenterol
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Kato T, Nakamori M, Matsumura S, Nakamura M, Ojima T, Fukuhara H, Ino Y, Todo T, Yamaue H.
Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer
Oncol Lett
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Sakuratani T, Takeuchi T, Yasufuku I, Iwata Y, Saigo C, Kito Y, Yoshida K.
Downregulation of ARID1A in gastric cancer cells: a putative protective molecular mechanism against the Harakiri-mediated apoptosis pathway.
Virchows Arch
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Nishibeppu K, Komatsu S, Kiuchi J, Kishimoto T, Takashima Y, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E.
TRIM37 contributes to malignant outcomes and CDDP resistance in gastric cancer.
J Cancer
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Kim S, Ahn JM, Bae WJ, Han JH, Lee D.
Quantitation of ligand is critical for ligand-dependent MET signalling activation and determines MET-targeted therapeutic response in gastric cancer.
Gastric Cancer
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24(3):577-588
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J Gastrointest Surg
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Anti-fibrotic properties of an adiponectin paralog protein, C1q/TNF-related protein 6 (CTRP6), in diffuse gastric adenocarcinoma.
J Cancer
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Laminin-411 and -511 Modulate the Proliferation, Adhesion, and Morphology of Gastric Cancer Cells.
Cell Biochem Biophys
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PubMed ID: 33629255
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FOXO3 is a latent tumor suppressor for FOXO3-positive and cytoplasmic-type gastric cancer cells.
Oncogene
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PubMed ID: 33795838
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Kurashima K, Shiozaki A, Kudou M, Shimizu H, Arita T, Kosuga T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
LRRC8A influences the growth of gastric cancer cells via the p53 signaling pathway.
Gastric Cancer
2021
PubMed ID: 33864161
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Kubo H, Murayama Y, Ogawa S, Matsumoto T, Yubakami M, Ohashi T, Kubota T, Okamoto K, Kamiya M, Urano Y, Otsuji E.
β-Galactosidase is a target enzyme for detecting peritoneal metastasis of gastric cancer.
Sci Rep
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11(1):10664
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Katsurahara K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
ANO9 regulates PD-L2 expression and binding ability to PD-1 in gastric cancer
Cancer Sci
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Matsumura S, Nakamori M, Tsuji T, Kato T, Nakamura M, Ojima T, Fukuhara H, Ino Y, Todo T, Yamaue H.
Oncolytic virotherapy with SOCS3 enhances viral replicative potency and oncolysis for gastric cancer
Oncotarget
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12(4):344-354
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20224
Ogawa S, Kubo H, Murayama Y, Kubota T, Yubakami M, Matsumoto T, Ohashi T, Okamoto K, Kuriki Y, Hanaoka K, Urano Y, Otsuji E.
Matrix metalloprotease-14 is a Target Enzyme for Detecting Peritoneal Metastasis in Gastric Cancer.
Photodiagnosis Photodyn Ther
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PubMed ID: 34242818
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Abe H, Kunita A, Otake Y, Kanda T, Kaneda A, Ushiku T, Fukayama M.
Virus-host interactions in carcinogenesis of Epstein-Barr virus-associated gastric carcinoma: Potential roles of lost ARID1A expression in its early stage.
PLoS One
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16(9):e0256440
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Zhang J, Wang F, Zhang H, Cao M.
A novel circular RNA circ_HN1/miR-628-5p/Ecto-5'-nucleotidase competing endogenous RNA network regulates gastric cancer development.
Bioengineered
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PubMed ID: 34637682
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Ito K, Kitajima Y, Kai K, Matsufuji S, Yamada K, Egawa N, Kitagawa H, Okuyama K, Tanaka T, Noshiro H.
Matrix metalloproteinase‑1 expression is regulated by HIF‑1‑dependent and epigenetic mechanisms and serves a tumor‑suppressive role in gastric cancer progression.
Int J Oncol
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Reyna-Jeldes M, De la Fuente-Ortega E, Cerda D, Velázquez-Miranda E, Pinto K, Vázquez-Cuevas FG, Coddou C.
Purinergic P2Y2 and P2X4 Receptors Are Involved in the Epithelial-Mesenchymal Transition and Metastatic Potential of Gastric Cancer Derived Cell Lines.
Pharmaceutics
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13(8)
PubMed ID: 34452195
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Nakamura K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
The expression of the alpha1 subunit of Na +/K +-ATPase is related to tumor development and clinical outcomes in gastric cancer
Gastric Cancer
2021
24(6):1278-1292
PubMed ID: 34251542
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16522
Kawatani M, Aono H, Hiranuma S, Shimizu T, Muroi M, Ogawa N, Ohishi T, Ohba SI, Kawada M, Nogawa T, Okano A, Hashizume D, Osada H.
Identification of a Small-Molecule Glucose Transporter Inhibitor, Glutipyran, That Inhibits Cancer Cell Growth
ACS Chem Biol
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16(8):1576-1586
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Egawa N, Tanaka T, Matsufuji S, Yamada K, Ito K, Kitagawa H, Okuyama K, Kitajima Y, Noshiro H.
Antitumor effects of low-dose tipifarnib on the mTOR signaling pathway and reactive oxygen species production in HIF-1α-expressing gastric cancer cells
FEBS Open Bio
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16896
Shiozaki A, Katsurahara K, Kudou M, Shimizu H, Kosuga T, Ito H, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Otsuji E.
Amlodipine and Verapamil, Voltage-Gated Ca 2+ Channel Inhibitors, Suppressed the Growth of Gastric Cancer Stem Cells
Ann Surg Oncol
2021
28(9):5400-5411
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Nakade H, Migita K, Matsumoto S, Wakatsuki K, Kunishige T, Miyao S, Sho M.
Overexpression of Cullin4A correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma.
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FARP1 boosts CDC42 activity from integrin αvβ5 signaling and correlates with poor prognosis of advanced gastric cancer.
Oncogenesis
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Uejima C, Morimoto M, Yamamoto M, Hara K, Miyauchi W, Sugezawa K, Tada Y, Tanio A, Kihara K, Matsunaga T, Tokuyasu N, Sakamoto T, Honjo S, Umekita Y, Fujiwara Y.
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Anticancer Res
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Microorganisms
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Baatar S, Bai T, Yokobori T, Gombodorj N, Nakazawa N, Ubukata Y, Kimura A, Kogure N, Sano A, Sohda M, Sakai M, Tumenjargal A, Ogata K, Kuwano H, Shirabe K, Saeki H.
High RAD18 Expression is Associated with Disease Progression and Poor Prognosis in Patients with Gastric Cancer
Ann Surg Oncol
2020
27(11):4360-4368
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Sano H, Futamura M, Gaowa S, Kamino H, Nakamura Y, Yamaguchi K, Tanaka Y, Yasufuku I, Nakakami A, Arakawa H, Yoshida K.
p53/Mieap-regulated mitochondrial quality control plays an important role as a tumor suppressor in gastric and esophageal cancers
Biochem Biophys Res Commun
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RNF126 as a Marker of Prognosis and Proliferation of Gastric Cancer
Anticancer Res
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He J, Ge Q, Lin Z, Shen W, Lin R, Wu J, Wang B, Lu Y, Chen L, Liu X, Zheng W, Zhang Y, Wang L, Wang K, Wang L, Zhuo W, Chen S.
MiR-129-5p induces cell cycle arrest through modulating HOXC10/Cyclin D1 to inhibit gastric cancer progression
FASEB J
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Gastric Cancer
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Front Pharmacol
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Oncotarget
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Folate receptor 1 (FOLR1) targeted chimeric antigen receptor (CAR) T cells for the treatment of gastric cancer.
PLoS ONE
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Kato R, Iwamuro M, Shiraha H, Horiguchi S, Tanaka E, Matsumoto K, Ohyama A, Sawahara H, Nagahara T, Uchida D, Tsutsumi K, Okada H.
Dipeptide γ-secretase inhibitor treatment enhances the anti-tumor effects of cisplatin against gastric cancer by suppressing cancer stem cell properties.
Oncol Lett
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IUBMB Life
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Oncol Rep
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Int J Oncol
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The activation of proteinase-activated receptor-1 (PAR1) promotes gastric cancer cell alteration of cellular morphology related to cell motility and invasion
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Loss of trefoil factor 1 is regulated by DNA methylation and is an independent predictive factor for poor survival in advanced gastric cancer
Int J Oncol
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J Antibiot (Tokyo)
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An Armed Oncolytic Herpes Simplex Virus Expressing thrombospondin-1 Has an Enhanced in Vivo Antitumor Effect Against Human Gastric Cancer
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Exp Ther Med
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Increased B7-H1 and B7-H4 Expressions on Circulating Monocytes and Tumor-Associated Macrophages are Involved in Immune Evasion in Patients with Gastric Cancer.
Yonago Acta Med
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Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer.
Am J Pathol
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Oncol Rep
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Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancer
BMC Cancer
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Otani K, Kitayama J, Kamei T, Soma D, Miyato H, Yamauchi T, Kadowaki T, Nagawa H.
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HIF-1alpha is an unfavorable determinant of relapse in gastric cancer patients who underwent curative surgery followed by adjuvant 5-FU chemotherapy.
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The activation of Proteinase-Activated Receptor-1 (PAR1) mediates gastric cancer cell proliferation and invasion
BMC Cancer
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Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines.
J. Surg. Res.
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Cancer-associated splicing variants of the CDCA1 and MSMB genes expressed in cancer cell lines and surgically resected gastric cancer tissues.
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FXYD3 protein involved in tumor cell proliferation is overproduced in human breast cancer tissues.
Biol Pharm Bull
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Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
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Interleukin-1alpha enhances angiogenesis and is associated with liver metastatic potential in human gastric cancer cell lines
J Surg Res
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Comparative analysis of intraperitoneal minimal free cancer cells between colorectal and gastric cancer patients using quantitative RT-PCR: possible reason for rare peritoneal recurrence in colorectal cancer.
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Yonago Acta medica
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World J Gastroenterol
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Exp Cell Res
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Biochem Biophys Res Commun
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Am J Pathol
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Superior antitumour activity of S-1 in tumours with a high dihydropyrimidine dehydrogenase activity.
Eur J Cancer
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Intermittent FLDP: 24-h infusion of 5-FU on days 1, 3 and 5 combined with low-dose cisplatin on days 1-5 for gastric cancer, and its pharmacologic and kinetic rationale.
Cancer Chemother Pharmacol
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Expression of trefoil peptides (TFF1, TFF2, and TFF3) in gastric carcinomas, intestinal metaplasia, and non-neoplastic gastric tissues
J Pathol
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Interleukin-1beta expression in human gastric carcinoma with Epstein-Barr virus infection.
J Virol
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Fujiwara H, Terashima M, Irinoda T, Takagane A, Abe K, Kashiwaba M, Oyama K, Takahashi M, Maesawa C, Saito K, Takechi T, Fukushima M.
Quantitative measurement of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA level in gastric cancer by real-time RT-PCR.
Jpn J Cancer Res
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Shinohara H, Morita S, Kawai M, Miyamoto A, Sonoda T, Pastan I, Tanigawa N.
Expression of HER2 in human gastric cancer cells directly correlates with antitumor activity of a recombinant disulfide-stabilized anti-HER2 immunotoxin.
J Surg Res
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Ijichi H, Ikenoue T, Kato N, Mitsuno Y, Togo G, Kato J, Kanai F, Shiratori Y, Omata M.
Systematic analysis of the TGF-beta-Smad signaling pathway in gastrointestinal cancer cells.
Biochem Biophys Res Commun
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Mass spectrometric high-throughput analysis of serum-free conditioned medium from cancer cell lines.
Cancer Lett
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Simple quantitative assay of alpha-fetoprotein mRNA in liver tissue using the real-time detection polymerase chain reaction assay - its application for clinical use.
Hepatol Res
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Transcriptional dysregulation of the p73L / p63 / p51 / p40 / KET gene in human squamous cell carcinomas: expression of Delta Np73L, a novel dominant-negative isoform, and loss of expression of the potential tumour suppressor p51.
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