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21570
Shirasaka Y, Yamada K, Etoh T, Noguchi K, Hasegawa T, Ogawa K, Kobayashi T, Nishizono A, Inomata M.
Cytocidal Effect of Irradiation on Gastric Cancer Cells Infected with a Recombinant Mammalian Orthoreovirus Expressing a Membrane-Targeted KillerRed.
Pharmaceuticals (Basel)
2024
17(1)
PubMed ID: 38256912
DOI: 10.3390/ph17010079
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19687
Mori Y, Nishikawa SG, Fratiloiu AR, Tsutsui M, Kataoka H, Joh T, Johnston RN.
Modulation of Reoviral Cytolysis (I): Combination Therapeutics
Viruses
2023
15(7):1472
PubMed ID: 37515160
DOI: 10.3390/v15071472
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19729
Sato T, Saito M, Nakajima S, Saito K, Katagata M, Fukai S, Okayama H, Sakamoto W, Saze Z, Momma T, Mimura K, Kono K.
ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer
Gastric Cancer
2023
26(3):379-392
PubMed ID: 36811690
DOI: 10.1007/s10120-023-01373-6
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19939
hiozaki A, Fukami T, Shimizu H, Kosuga T, Kudou M, Takemoto K, Katsurahara K, Nishibeppu K, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Otsuji E.
Effects of TRPV2 on the Expression of PD-L1 and Its Binding Ability to PD-1 in Gastric Cancer
Ann Surg Oncol
2023
30(13):8704-8716
PubMed ID: 37599296
DOI: 10.1245/s10434-023-14084-0
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19973
Fukai S, Nakajima S, Saito M, Saito K, Kase K, Nakano H, Sato T, Sakuma M, Kaneta A, Okayama H, Mimura K, Sakamoto W, Saze Z, Momma T, Kono K.
Down-regulation of stimulator of interferon genes (STING) expression and CD8+ T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer
Gastric Cancer
2023
26(6):878-890
PubMed ID: 37542528
DOI: 10.1007/s10120-023-01417-x
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21486
Lou M, Iwatsuki M, Wu X, Zhang W, Matsumoto C, Baba H.
Cancer-Associated Fibroblast-Derived IL-8 Upregulates PD-L1 Expression in Gastric Cancer Through the NF-κB Pathway.
Ann Surg Oncol
2023
PubMed ID: 38006530
DOI: 10.1245/s10434-023-14586-x
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17567
Takashima Y, Komatsu S, Ohashi T, Kiuchi J, Kamiya H, Shimizu H, Arita T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E.
Overexpression of Tetraspanin31 contributes to malignant potential and poor outcomes in gastric cancer
Cancer Sci
2022
113(6):1984-1998
PubMed ID: 35307915
DOI: 10.1111/cas.15342
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20459
Kato S, Shiozaki A, Kudou M, Shimizu H, Kosuga T, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
TRPV2 Promotes Cell Migration and Invasion in Gastric Cancer via the Transforming Growth Factor-β Signaling Pathway.
Ann Surg Oncol
2022
PubMed ID: 34855064
DOI: 10.1245/s10434-021-11132-5
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20571
Fu L, Yonemura A, Yasuda-Yoshihara N, Umemoto T, Zhang J, Yasuda T, Uchihara T, Akiyama T, Kitamura F, Yamashita K, Okamoto Y, Bu L, Wei F, Hu X, Liu Y, Ajani JA, Tan P, Baba H, Ishimoto T.
Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer.
Gastric Cancer
2022
PubMed ID: 35166958
DOI: 10.1007/s10120-022-01283-z
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20622
Takaki W, Konishi H, Matsubara D, Shoda K, Arita T, Kataoka S, Shibamoto J, Furuke H, Takabatake K, Shimizu H, Komatsu S, Shiozaki A, Kubota T, Okamoto K, Otsuji E.
Role of Extracellular High-Mobility Group Box-1 as a Therapeutic Target of Gastric Cancer.
Int J Mol Sci
2022
23(6)
PubMed ID: 35328684
DOI: 10.3390/ijms23063264
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20627
Soda T, Gen Y, Terasaki K, Iwai N, Kitaichi T, Dohi O, Taketani H, Seko Y, Umemura A, Nishikawa T, Yamaguchi K, Moriguchi M, Konishi H, Naito Y, Itoh Y, Yasui K.
Loss of KAP3 decreases intercellular adhesion and impairs intracellular transport of laminin in signet ring cell carcinoma of the stomach.
Sci Rep
2022
12(1):5050
PubMed ID: 35322078
DOI: 10.1038/s41598-022-08904-8
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20661
Inoue H, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
Functions and Clinical Significance of CACNA2D1 in Gastric Cancer.
Ann Surg Oncol
2022
PubMed ID: 35445337
DOI: 10.1245/s10434-022-11752-5
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21996
Fukami T, Shiozaki A, Kosuga T, Kudou M, Shimizu H, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Morinaga Y, Konishi E, Otsuji E.
Anoctamin 5 regulates the cell cycle and affects prognosis in gastric cancer
World J Gastroenterol
2022
28(32):4649-4667.
PubMed ID: 36157935
DOI: 10.3748/wjg.v28.i32.4649
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13323
Nishibeppu K, Komatsu S, Kiuchi J, Kishimoto T, Takashima Y, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E.
TRIM37 contributes to malignant outcomes and CDDP resistance in gastric cancer.
J Cancer
2021
PubMed ID: 33391428
DOI: 10.7150/jca.47577
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Iwata Y, Yasufuku I, Saigo C, Kito Y, Takeuchi T, Yoshida K.
Anti-fibrotic properties of an adiponectin paralog protein, C1q/TNF-related protein 6 (CTRP6), in diffuse gastric adenocarcinoma.
J Cancer
2021
12(4):1161-1168
PubMed ID: 33442414
DOI: 10.7150/jca.46765
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Kurashima K, Shiozaki A, Kudou M, Shimizu H, Arita T, Kosuga T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
LRRC8A influences the growth of gastric cancer cells via the p53 signaling pathway.
Gastric Cancer
2021
PubMed ID: 33864161
DOI: 10.1007/s10120-021-01187-4
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14345
Katsurahara K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
ANO9 regulates PD-L2 expression and binding ability to PD-1 in gastric cancer
Cancer Sci
2021
112(3):1026-1037.
PubMed ID: 33404124
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Nakamura K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
The expression of the alpha1 subunit of Na +/K +-ATPase is related to tumor development and clinical outcomes in gastric cancer
Gastric Cancer
2021
24(6):1278-1292
PubMed ID: 34251542
DOI: 10.1007/s10120-021-01212-6
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16229
Wenzhe Li, Atsushi Okabe, Genki Usui, Masaki Fukuyo, Keisuke Matsusaka, Bahityar Rahmutulla, Yasunobu Mano, Takayuki Hoshii, Sayaka Funata, Nobuhiro Hiura, Masashi Fukayama, Patrick Tan, Tetsuo Ushiku, Atsushi Kaneda
Activation of EHF via STAT3 phosphorylation by LMP2A in Epstein-Barr virus-positive gastric cancer
Cancer Sci
2021
112(8):3349-3362
PubMed ID: 34014591
DOI: 10.1111/cas.14978
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16861
Kunzke T, Hölzl FT, Prade VM, Buck A, Huber K, Feuchtinger A, Ebert K, Zwingenberger G, Geffers R, Hauck SM, Haffner I, Luber B, Lordick F, Walch A.
Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2-positive advanced gastric cancer
Clin Transl Med
2021
11(9):e547.
PubMed ID: 34586736
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Hirano T, Shinsato Y, Tanabe K, Higa N, Kamil M, Kawahara K, Yamamoto M, Minami K, Shimokawa M, Arigami T, Yanagita S, Matushita D, Uenosono Y, Ishigami S, Kijima Y, Maemura K, Kitazono I, Tanimoto A, Furukawa T, Natsugoe S.
FARP1 boosts CDC42 activity from integrin αvβ5 signaling and correlates with poor prognosis of advanced gastric cancer.
Oncogenesis
2020
PubMed ID: 32029704
DOI: 10.1038/s41389-020-0190-7
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13023
Berlamont H, De Witte C, Bauwens E, Min Jou H, Ducatelle R, De Meester E, Gansemans Y, Deforce D, Van Nieuwerburgh F, Haesebrouck F, Smet A.
Distinct transcriptome signatures of Helicobacter suis and Helicobacter heilmannii strains upon adherence to human gastric epithelial cells.
Vet Res
2020
PubMed ID: 32381076
DOI: 10.1186/s13567-020-00786-w
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Okabe A, Huang KK, Matsusaka K, Fukuyo M, Xing M, Ong X, Hoshii T, Usui G, Seki M, Mano Y, Rahmutulla B, Kanda T, Suzuki T, Rha SY, Ushiku T, Fukayama M, Tan P, Kaneda A.
Cross-species chromatin interactions drive transcriptional rewiring in Epstein-Barr virus-positive gastric adenocarcinoma.
Nat Genet
2020
PubMed ID: 32719515
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13315
Ebert K, Zwingenberger G, Barbaria E, Keller S, Heck C, Arnold R, Hollerieth V, Mattes J, Geffers R, Raimúndez E, Hasenauer J, Luber B.
Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines.
BMC Cancer
2020
PubMed ID: 33115415
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Hinata M, Kunita A, Abe H, Morishita Y, Sakuma K, Yamashita H, Seto Y, Ushiku T, Fukayama M.
Exosomes of Epstein-Barr Virus-Associated Gastric Carcinoma Suppress Dendritic Cell Maturation.
Microorganisms
2020
PubMed ID: 33198173
DOI: 10.3390/microorganisms8111776
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Baatar S, Bai T, Yokobori T, Gombodorj N, Nakazawa N, Ubukata Y, Kimura A, Kogure N, Sano A, Sohda M, Sakai M, Tumenjargal A, Ogata K, Kuwano H, Shirabe K, Saeki H.
High RAD18 Expression is Associated with Disease Progression and Poor Prognosis in Patients with Gastric Cancer
Ann Surg Oncol
2020
27(11):4360-4368
PubMed ID: 32356270
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13525
Asakawa Y, Okabe A, Fukuyo M, Li W, Ikeda E, Mano Y, Funata S, Namba H, Fujii T, Kita K, Matsusaka K, Kaneda A.
Epstein-Barr virus-positive gastric cancer involves enhancer activation through activating transcription factor 3
Cancer Sci
2020
111(5):1818-1828
PubMed ID: 32119176
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13600
Sano H, Futamura M, Gaowa S, Kamino H, Nakamura Y, Yamaguchi K, Tanaka Y, Yasufuku I, Nakakami A, Arakawa H, Yoshida K.
p53/Mieap-regulated mitochondrial quality control plays an important role as a tumor suppressor in gastric and esophageal cancers
Biochem Biophys Res Commun
2020
529(3):582-589.
PubMed ID: 32736677
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Saito S, Kitamura-Muramatsu Y, Komine F, Polat M, Takeshima SN, Takei M, Aida Y.
Absence of bovine leukemia virus proviral DNA in Japanese human blood cell lines and human cancer cell lines
Arch Virol
2020
165(1):207-214
PubMed ID: 31776677
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11505
Kageyama-Yahara N, Yamamichi N, Takahashi Y, Takeuchi C, Matsumoto Y, Sakaguchi Y, Koike K.
Tandem repeats of the 5' flanking region of human MUC5AC have a role as a novel enhancer in MUC5AC gene expression.
Biochem Biophys Rep
2019
18:100632
PubMed ID: 30993217
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De Witte C, Demeyere K, De Bruyckere S, Taminiau B, Daube G, Ducatelle R, Meyer E, Haesebrouck F.
Characterization of the non-glandular gastric region microbiota in Helicobacter suis-infected versus non-infected pigs identifies a potential role for Fusobacterium gastrosuis in gastric ulceration.
Vet. Res.
2019
50(1):39
PubMed ID: 31126330
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S Zhang et al
Sensitization of Gastric Cancer Cells to Irinotecan by p53 Activation
BPB Reports
2019
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Wu D, Yan J, Shen X, Sun Y, Thulin M, Cai Y, Wik L, Shen Q, Oelrich J, Qian X, Dubois KL, Ronquist KG, Nilsson M, Landegren U, Kamali-Moghaddam M.
Profiling surface proteins on individual exosomes using a proximity barcoding assay
Nat Commun
2019
10(1):3854
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Shimada S, Akiyama Y, Mogushi K, Ishigami-Yuasa M, Kagechika H, Nagasaki H, Fukamachi H, Yuasa Y, Tanaka S.
Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models.
Br. J. Cancer
2018
118:972-984
PubMed ID: 29527007
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Li W, Wong CC, Zhang X, Kang W, Nakatsu G, Zhao Q, Chen H, Go MYY, Chiu PWY, Wang X, Ji J, Li X, Cai Z, Ng EKW, Yu J.
CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis.
Oncogene
2018
37(50):6383-6398
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Kim M, Pyo S, Kang CH, Lee CO, Lee HK, Choi SU, Park CH.
Folate receptor 1 (FOLR1) targeted chimeric antigen receptor (CAR) T cells for the treatment of gastric cancer.
PLoS ONE
2018
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Wang Z, Qu H, Gong W, Liu A.
Up-regulation and tumor-promoting role of SPHK1 were attenuated by miR-330-3p in gastric cancer.
IUBMB Life
2018
PubMed ID: 30281914
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Keller S, Zwingenberger G, Ebert K, Hasenauer J, Wasmuth J, Maier D, Haffner I, Schierle K, Weirich G, Luber B.
Effects of trastuzumab and afatinib on kinase activity in gastric cancer cell lines.
Mol Oncol
2018
PubMed ID: 29325228
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Kiuchi J, Komatsu S, Imamura T, Nishibeppu K, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Ichikawa D, Tsuda H, Otsuji E.
Overexpression of YEATS4 contributes to malignant outcomes in gastric carcinoma.
Am J Cancer Res
2018
PubMed ID: 30662802
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Yoshioka T, Shien K, Namba K, Torigoe H, Sato H, Tomida S, Yamamoto H, Asano H, Soh J, Tsukuda K, Nagasaka T, Fujiwara T, Toyooka S.
Antitumor activity of pan-HER inhibitors in HER2-positive gastric cancer.
Cancer Sci.
2018
109(4):1166-1176
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Gaowa S, Futamura M, Tsuneki M, Kamino H, Tajima JY, Mori R, Arakawa H, Yoshida K.
Possible role of p53/Mieap-regulated mitochondrial quality control as a tumor suppressor in human breast cancer.
Cancer Sci
2018
PubMed ID: 30290054
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Deguchi Y, Okabe H, Oshima N, Hisamori S, Minamiguchi S, Muto M, Sakai Y.
PTEN loss is associated with a poor response to trastuzumab in HER2-overexpressing gastroesophageal adenocarcinoma.
Gastric Cancer
2017
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Ooi A, Oyama T, Nakamura R, Tajiri R, Ikeda H, Fushida S, Dobashi Y.
Gene amplification of CCNE1, CCND1, and CDK6 in gastric cancers detected by multiplex ligation-dependent probe amplification and fluorescence in situ hybridization.
Hum. Pathol.
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Kneissl J, Hartmann A, Pfarr N, Erlmeier F, Lorber T, Keller S, Zwingenberger G, Weichert W, Luber B.
Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines.
J. Cancer Res. Clin. Oncol.
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Qian Y, Wong CC, Xu J, Chen H, Zhang Y, Kang W, Wang H, Zhang L, Li W, Chu ESH, Go MYY, Chiu PWY, Ng EKW, Chan FKL, Sung JJY, Si J, Yu J.
Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation.
Cancer Res.
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ASPP2 suppresses invasion and TGF-β1-induced epithelial-mesenchymal transition by inhibiting Smad7 degradation mediated by E3 ubiquitin ligase ITCH in gastric cancer.
Cancer Lett.
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Yanoma T, Ogata K, Yokobori T, Ide M, Mochiki E, Toyomasu Y, Yanai M, Kogure N, Kimura A, Suzuki M, Nakazawa N, Bai T, Oyama T, Asao T, Shirabe K, Kuwano H.
Heat shock-induced HIKESHI protects cell viability via nuclear translocation of heat shock protein 70.
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Locoregional therapy with α-emitting trastuzumab against peritoneal metastasis of human epidermal growth factor receptor 2-positive gastric cancer in mice.
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The H19-PEG10/IGF2BP3 axis promotes gastric cancer progression in patients with high lymph node ratios.
Oncotarget
2017
8:74567-74581
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Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.
Cancer Sci
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108(5):931-940
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Okabe A, Funata S, Matsusaka K, Namba H, Fukuyo M, Rahmutulla B, Oshima M, Iwama A, Fukayama M, Kaneda A.
Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus
Sci Rep
2017
7(1):7924
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Nambara S, Masuda T, Nishio M, Kuramitsu S, Tobo T, Ogawa Y, Hu Q, Iguchi T, Kuroda Y, Ito S, Eguchi H, Sugimachi K, Saeki H, Oki E, Maehara Y, Suzuki A, Mimori K.
Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer
Oncotarget
2017
8(64):107666-107677
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Funata S, Matsusaka K, Yamanaka R, Yamamoto S, Okabe A, Fukuyo M, Aburatani H, Fukayama M, Kaneda A.
Histone modification alteration coordinated with acquisition of promoter DNA methylation during Epstein-Barr virus infection
Oncotarget
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Ito M, Migita K, Matsumoto S, Wakatsuki K, Tanaka T, Kunishige T, Nakade H, Nakatani M, Nakajima Y.
Overexpression of E3 ubiquitin ligase tripartite motif 32 correlates with a poor prognosis in patients with gastric cancer
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Sci Rep
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Divergence between the Highly Virulent Zoonotic Pathogen Helicobacter heilmannii and Its Closest Relative, the Low-Virulence "Helicobacter ailurogastricus" sp. nov.
Infect. Immun.
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The Helicobacter heilmannii hofE and hofF Genes are Essential for Colonization of the Gastric Mucosa and Play a Role in IL-1β-Induced Gastric MUC13 Expression.
Helicobacter
2016
21:504-522
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Saju P, Murata-Kamiya N, Hayashi T, Senda Y, Nagase L, Noda S, Matsusaka K, Funata S, Kunita A, Urabe M, Seto Y, Fukayama M, Kaneda A, Hatakeyama M.
Host SHP1 phosphatase antagonizes Helicobacter pylori CagA and can be downregulated by Epstein-Barr virus.
Nat Microbiol
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Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer.
Proc. Natl. Acad. Sci. U.S.A.
2016
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P. Li, Chenghong Wang, Sen Guo, Z. Zhang
Neuropilin 2 could promote gastric adenocarcinoma lymphatic invasionwith VEGF-C stimulation
Int J Clin Exp Med
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Oncotarget
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Takeda S, Tanigawa T, Watanabe T, Tatsuwaki H, Nadatani Y, Otani K, Nagami Y, Tanaka F, Kamata N, Yamagami H, Shiba M, Tominaga K, Fujiwara Y, Muguruma K, Ohira M, Hirakawa K, Arakawa T.
Reduction of prostaglandin transporter predicts poor prognosis associated with angiogenesis in gastric adenocarcinoma
J Gastroenterol Hepatol
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31(2):376-83
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