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細胞番号 : 細胞名
RCB0987 : C2C12  update : 2024/04/18
細胞特性(Comment:英)Said differentiate to myotubes, but need confirmation. Since “Terms and conditions” etc. for this cell line can be changed, the users of this cell line must refer to ECACC 91031101 prior to order.
細胞特性(日)マウス筋芽細胞株で条件により急速に筋肉細胞(myotube)に分化する 。ECACC由来株。使用条件等がECACCによって随時変更となる可能性があります。ご購入前に、 ECACC 91031101 を必ずご参照ください。
細胞特性(寄託者記述:英)
細胞特性(寄託者記述:日)
使用条件(英)1) There is no restriction regarding use for basic researches. However, since “Terms and conditions” etc. for this cell line can be changed, the users of this cell line must refer to ECA91031101 prior to order. 2) In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
使用条件(日)1) 基礎的研究につきましては、使用制限はありません。しかし、使用条件等がECACCによって随時変更となる可能性があるので、購入前に、ECA91031101 を必ず参照すること。2) 商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。
備考(英)
備考(日)
提供申込書類(英) Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 ECACC
寄託日 1994
動物種 _mouse < Mammals
動物系統名 C3H
採取組織 muscle
細胞分類 other
入手歴 overseas, ECACC
細胞寿命 infinite
細胞形態 other
Cellosaurus(Expasy) CVCL_0188
細胞培養・検査情報
寄託時情報
ロット情報
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 DMEM (low glucose) + 10% FBS
抗生物質 Free
継代方法 0.25% Trypsin
継代密度 1 : 10-20 split
継代・培地交換頻度 Subculture : once/2-3 days
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
動物種PCR OK
マウス系統検査 OK
画像情報
寄託時情報
ロット情報
文献情報 Reference(英) 3件
Reference(日) 0件
利用者成果(英) 334件
利用者成果(日) 1件

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Reference(英)
4921  atagiri T, Yamaguchi A, Komaki M, Abe E, Takahashi N, Ikeda T, Rosen V, Wozney JM, Fujisawa-Sehara A, Suda T.  Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage.  J Cell Biol  1994  127(6 Pt 1):1755-66.  PubMed ID: 7798324   DOI: 10.1083/jcb.127.6.1755
4920  Blau HM, Pavlath GK, Hardeman EC, Chiu CP, Silberstein L, Webster SG, Miller SC, Webster C.  Plasticity of the differentiated state.  Science  1985  230(4727):758-66  PubMed ID: 2414846   DOI: 10.1126/science.2414846
1832  Yaffe D, Saxel O  Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle.  Nature  1977  270:725-7  PubMed ID: 563524   DOI: 10.1038/270725a0

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Reference(日)

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利用者成果(英)
19858  Mohamad Ishak NS, Kikuchi M, Ikemoto K.  Dietary pyrroloquinoline quinone hinders aging progression in male mice and D-galactose-induced cells  Front Aging  2024  5:1351860  PubMed ID: 38487591   DOI: 10.3389/fragi.2024.1351860
21611  Fu X, Murakami M, Hashimoto O, Matsui T, Funaba M.  Regulatory mechanisms underlying interleukin-6 expression in murine brown adipocytes.  Cell Biochem Funct  2024  42(1):e3915  PubMed ID: 38269513   DOI: 10.1002/cbf.3915
21625  Jo-Watanabe A, Inaba T, Osada T, Hashimoto R, Nishizawa T, Okuno T, Ihara S, Touhara K, Hattori N, Oh-Hora M, Nureki O, Yokomizo T.  Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury.  Nat Commun  2024  15(1):1530  PubMed ID: 38413581   DOI: 10.1038/s41467-024-45579-3
21656  Kashiwagi R, Udono M, Katakura Y.  Fructobacillus fructosus OS-1010 strain stimulates intestinal cells to secrete exosomes that activate muscle cells.  Cytotechnology  2024  76(2):209-216  PubMed ID: 38495295   DOI: 10.1007/s10616-023-00610-1
17751  Norikura T, Sasaki Y, Kojima-Yuasa A, Kon A.  Glyoxylic Acid, an α-Keto Acid Metabolite Derived from Glycine, Promotes Myogenesis in C2C12 Cells  Nutrients  2023  15(7):1763  PubMed ID: 37049603   DOI: 10.3390/nu15071763
17752  Nakagawara K, Takeuchi C, Ishige K.  5'-CMP and 5'-UMP alleviate dexamethasone-induced muscular atrophy in C2C12 myotubes  Biochem Biophys Rep  2023  34:101460  PubMed ID: 37020790   DOI: 10.1016/j.bbrep.2023.101460
17753  Jing Z, Iba T, Naito H, Xu P, Morishige JI, Nagata N, Okubo H, Ando H.  L-carnitine prevents lenvatinib-induced muscle toxicity without impairment of the anti-angiogenic efficacy  Front Pharmacol   2023  14:1182788  PubMed ID: 37089945   DOI: 10.3389/fphar.2023.1182788
19559  Hirono Ohashi, Shunsuke Shigaki, Ryo Teramae, Masahiro Shimizu, Koh Hosoda  Development of Bio-cultured Artificial Muscles with High Design Flexibility  Journal of Bionic Engineering  2023  20:1635-1645    DOI: 10.1007/s42235-023-00355-9
19560  Elvitigala KCML, Mubarok W, Sakai S.  Tuning the crosslinking and degradation of hyaluronic acid/gelatin hydrogels using hydrogen peroxide for muscle cell sheet fabrication  Soft Matter  2023  19(31):5880-5887.  PubMed ID: 37439099   DOI: 10.1039/d3sm00560g
19561  Hayata Okino, Ryota Yamada, Shunta Muraki, Motonari Suzuki, Shinya Kumagai  Microperfusion cell culture system for promoted cell growth using non-thermal atmospheric pressure plasma exposure  Japanese Journal of Applied Physics  2023  62:SG1043    DOI: 10.35848/1347-4065/acc03c
19562  Kitakaze T, Tatsumi R, Yamaguchi M, Nakatsuji A, Harada N, Yamaji R.  All- Trans Retinoic Acid-Responsive LGR6 Is Transiently Expressed during Myogenic Differentiation and Is Required for Myoblast Differentiation and Fusion  Int J Mol Sci  2023  24(10):9035  PubMed ID: 37240382   DOI: 10.3390/ijms24109035
19656  Tanimoto A, Yamaguchi Y, Kadowaki T, Sakai E, Oyakawa S, Ono Y, Yoshida N, Tsukuba T.  Rab44 negatively regulates myoblast differentiation by controlling fusogenic protein transport and mTORC1 signaling  J Cell Biochem  2023  124(10):1486-1502  PubMed ID: 37566644   DOI: 10.1002/jcb.30457
21013  Shintani-Ishida K, Tsurumi R, Ikegaya H.  Decrease in the expression of muscle-specific miRNAs, miR-133a and miR-1, in myoblasts with replicative senescence.  PLoS One  2023  18(1):e0280527  PubMed ID: 36649291   DOI: 10.1371/journal.pone.0280527
21024  Araki H, Hino S, Anan K, Kuribayashi K, Etoh K, Seko D, Takase R, Kohrogi K, Hino Y, Ono Y, Araki E, Nakao M.  LSD1 defines the fiber type-selective responsiveness to environmental stress in skeletal muscle.  Elife  2023    PubMed ID: 36695573   DOI: 10.7554/eLife.84618
21164  Matsuba I, Fujita R, Iida K.  Palmitic Acid Inhibits Myogenic Activity and Expression of Myosin Heavy Chain MHC IIb in Muscle Cells through Phosphorylation-Dependent MyoD Inactivation.  Int J Mol Sci  2023  24(6)  PubMed ID: 36982919   DOI: 10.3390/ijms24065847
21236  Sato K, Miyauchi Y, Xu X, Kon R, Ikarashi N, Chiba Y, Hosoe T, Sakai H.  Platinum-based anticancer drugs-induced downregulation of myosin heavy chain isoforms in skeletal muscle of mouse.  J Pharmacol Sci  2023  152(3):167-177  PubMed ID: 37257944   DOI: 10.1016/j.jphs.2023.04.009
21245  Iwai S, Kaji K, Nishimura N, Kubo T, Tomooka F, Shibamoto A, Suzuki J, Tsuji Y, Fujinaga Y, Kitagawa K, Namisaki T, Akahane T, Yoshiji H.  Glucagon-like peptide-1 receptor agonist, semaglutide attenuates chronic liver disease-induced skeletal muscle atrophy in diabetic mice.  Biochim Biophys Acta Mol Basis Dis  2023  166770  PubMed ID: 37276988   DOI: 10.1016/j.bbadis.2023.166770
21279  Takakura Y, Suzuki T, Hirai N, Araki T, Ohishi M, Sato H, Yamaguchi N, Takano H, Yamaguchi N.  VGLL3 confers slow-twitch muscle differentiation via PGC-1α expression in C2C12 myocytes.  Biochem Biophys Res Commun  2023  669:30-37  PubMed ID: 37262950   DOI: 10.1016/j.bbrc.2023.05.073
21292  Endo S, Uto A, Miyashita K, Sato M, Inoue H, Fujii K, Hagiwara A, Ryuzaki M, Oshida T, Kinouchi K, Itoh H.  Intermittent Fasting Sustainably Improves Glucose Tolerance in Normal Weight Male Mice Through Histone Hyperacetylation.  J Endocr Soc  2023  7(7):bvad082  PubMed ID: 37362383   DOI: 10.1210/jendso/bvad082
21389  Sato K, Satoshi Y, Miyauchi Y, Sato F, Kon R, Ikarashi N, Chiba Y, Hosoe T, Sakai H.  Downregulation of PGC-1α during cisplatin-induced muscle atrophy in murine skeletal muscle.  Biochim Biophys Acta Mol Basis Dis  2023  1870(1):166877  PubMed ID: 37673360   DOI: 10.1016/j.bbadis.2023.166877
21425  Kametaka S, Isobe M, Komata K, Morinaga M, Nagahata K, Lee-Hotta S, Uchiyama Y, Shibata M, Sugiura H.  Protective effects of hachimijiogan (HJG), a Japanese Kampo medicine, on cancer cachectic muscle wasting in mice.  Biomed Res  2023  44(5):199-207  PubMed ID: 37779032   DOI: 10.2220/biomedres.44.199
21430  Mori K, Kataoka K, Akiyama Y, Asahi T.  Covalent Immobilization of Collagen Type I to a Polydimethylsiloxane Surface for Preventing Cell Detachment by Retaining Collagen Molecules under Uniaxial Cyclic Mechanical Stretching Stress.  Biomacromolecules  2023    PubMed ID: 37800307   DOI: 10.1021/acs.biomac.3c00669
21473  Hirai T, Wang W, Murono N, Iwasa K, Inoue M.  Potential role of Akt in the regulation of fibroblast growth factor 21 by berberine.  J Nat Med  2023    PubMed ID: 37951850   DOI: 10.1007/s11418-023-01755-1
21499  Minami E, Sasa K, Yamada A, Kawai R, Yoshida H, Nakano H, Maki K, Kamijo R.  Lactate-induced histone lactylation by p300 promotes osteoblast differentiation.  PLoS One  2023  18(12):e0293676  PubMed ID: 38051708   DOI: 10.1371/journal.pone.0293676
21525  Kimira Y, Osawa K, Osawa Y, Mano H.  Preventive Effects of Collagen-Derived Dipeptide Prolyl-Hydroxyproline against Dexamethasone-Induced Muscle Atrophy in Mouse C2C12 Skeletal Myotubes.  Biomolecules  2023  13(11)  PubMed ID: 38002299   DOI: 10.3390/biom13111617
17501  Yasukuni R, Koyanagi A, Tanaka Y, Okano K, Hosokawa Y.  Cell viability assessment associated with a contact of gas bubbles produced by femtosecond laser breakdown in cell culture media  Sci Rep  2022  12(1):19001  PubMed ID: 36347928   DOI: 10.1038/s41598-022-23733-5
17552  Takasawa S, Shobatake R, Itaya-Hironaka A, Makino M, Uchiyama T, Sakuramoto-Tsuchida S, Takeda Y, Ota H, Yamauchi A.  Upregulation of IL-8, osteonectin, and myonectin mRNAs by intermittent hypoxia via OCT1- and NRF2-mediated mechanisms in skeletal muscle cells  J Cell Mol Med  2022  ;26(24):6019-6031  PubMed ID: 36457269   DOI: 10.1111/jcmm.17618
17566  Kobayashi Y, Asayama S.  Design of the Zinc Ion and Plasmid DNA Co-Delivery System by Poly(1-Vinylimidazole) Derivatives for Myoblast Differentiation  ACS Appl Bio Mater  2022  5(12):5754-5761  PubMed ID: 36459414   DOI: 10.1021/acsabm.2c00737
17584  Suzuki M, Kimura T, Yoshida Y, Kobayashi M, Hashimoto Y, Takahashi H, Shimizu T, Anzai S, Nakamura N, Kishida A.  In Vitro Tissue Reconstruction Using Decellularized Pericardium Cultured with Cells for Ligament Regeneration  Polymers (Basel)  2022  14(12):2351  PubMed ID: 35745927   DOI: 10.3390/polym14122351
17589  Dian Anggraini, Wildan Mubarok, Yoichiroh Hosokawa, Koji Eto, Shiro Suetsugu, Yaxiaer Yalikun  Reverse sorting of immortalized megakaryocyte progenitor cell lines (imMKCLs) by femtosecond laser scanning  Applied Physics Express  2022  15:107001    DOI: 10.35848/1882-0786/ac8f17
17597  Sasaki Y, Kojima-Yuasa A, Tadano H, Mizuno A, Kon A, Norikura T.  Ursolic acid improves the indoxyl sulfate-induced impairment of mitochondrial biogenesis in C2C12 cells  Nutr Res Pract  2022  16(2):147-160  PubMed ID: 35392531   DOI: 10.4162/nrp.2022.16.2.147
17672  Imashiro C, Mei J, Friend J, Takemura K.  Quantifying cell adhesion through forces generated by acoustic streaming  Ultrason Sonochem  2022  90:106204  PubMed ID: 36257212   DOI: 10.1016/j.ultsonch.2022.106204
20454  Ishikawa K, Araki M, Nagano Y, Motoda A, Shishido T, Kurashige T, Takahashi T, Morino H, Kawakami H, Matsumoto M, Maruyama H.  Knockdown of optineurin controls C2C12 myoblast differentiation via regulating myogenin and MyoD expressions.  Differentiation  2022  123:1-8  PubMed ID: 34844057   DOI: 10.1016/j.diff.2021.11.004
20525  Hosaka YZ, Washie S, Warita K.  Preliminary study of the gene expression of sulfation and degradation enzymes for chondroitin sulfate in glycerol-treated C2C12 myoblast cells.  J Vet Med Sci  2022    PubMed ID: 35022360   DOI: 10.1292/jvms.21-0632
20555  Ikeno Y, Inomata M, Tsukimura Y, Suzuki Y, Takeuchi H, Harada Y, Kon R, Ikarashi N, Chiba Y, Yamada T, Kamei J, Sakai H.  Eicosapentaenoic acid suppresses cisplatin-induced muscle atrophy by attenuating the up-regulated gene expression of ubiquitin.  J Nutr Biochem  2022  108953  PubMed ID: 35121023   DOI: 10.1016/j.jnutbio.2022.108953
20574  Satoh F, Sugiura A, Tashiro J, Hosaka YZ, Warita K.  Chondroitin sulfate E downregulates N-cadherin and suppresses myotube formation.  J Vet Med Sci  2022    PubMed ID: 35173094   DOI: 10.1292/jvms.21-0662
16325  Mizutani S, Oyabu M, Yamamoto A, Uchitomi R, Sugimoto T, Kamei Y.  Vitamin D Activates Various Gene Expressions, Including Lipid Metabolism, in C2C12 Cells  J Nutr Sci Vitaminol (Tokyo)  2022  68(1):65-72  PubMed ID: 35228497   DOI: 10.3177/jnsv.68.65
16358  Oyabu M, Takigawa K, Mizutani S, Hatazawa Y, Fujita M, Ohira Y, Sugimoto T, Suzuki O, Tsuchiya K, Suganami T, Ogawa Y, Ishihara K, Miura S, Kamei Y.  FOXO1 cooperates with C/EBPδ and ATF4 to regulate skeletal muscle atrophy transcriptional program during fasting  FASEB J  2022  36(2):e22152  PubMed ID: 35061305   DOI: 10.1096/fj.202101385RR
16359  Ou Y, Jobu K, Ishida T, Morisawa S, Fujita H, Kawada K, Yoshioka S, Miyamura M.  Saikokeishikankyoto extract alleviates muscle atrophy in KKAy mice  J Nat Med  2022  76(2):379-388  PubMed ID: 34997408   DOI: 10.1007/s11418-021-01590-2
20669  Nakahata M, Tominaga N, Saito K, Nishiyama K, Tanino Y, Saiki K, Kojima M, Sakai S.  A bio-synthetic hybrid hydrogel formed under physiological conditions consisting of mucin and a synthetic polymer carrying boronic acid.  Macromol Biosci  2022  e2200055  PubMed ID: 35429097   DOI: 10.1002/mabi.202200055
20675  Fu X, Matsui T, Funaba M.  Enhancement of vitamin C-induced myogenesis by inhibition of extracellular signal-regulated kinase (ERK) 1/2 pathway.  Biochem Biophys Res Commun  2022  612:57-62  PubMed ID: 35504090   DOI: 10.1016/j.bbrc.2022.04.103
20709  Sawa R, Ohnishi A, Ohno M, Nagata M, Wake I, Okimura Y.  Specific amino acids regulate Sestrin2 mRNA and protein levels in an ATF4-dependent manner in C2C12 myocytes.  Biochim Biophys Acta Gen Subj  2022  130174  PubMed ID: 35597502   DOI: 10.1016/j.bbagen.2022.130174
16636  Kazuya Furusawa, Ryo Teramae, Hirono Ohashi, Masahiro Shimizu  Development of Living “Bio-Robots” for Autonomous Actuations  Journal of Robotics and Mechatronics  2022  34:279-284    DOI: 10.20965/jrm.2022.p0279
20738  Yamamoto M, Miyata S.  Influences of Microscopic Imaging Conditions on Accuracy of Cell Morphology Discrimination Using Convolutional Neural Network of Deep Learning.  Micromachines (Basel)  2022  13(5)  PubMed ID: 35630227   DOI: 10.3390/mi13050760
16660  Matsumoto A, Tsuda H, Furui S, Kawada-Nagashima M, Anzai T, Seki M, Watanabe K, Muramatsu K, Osaka H, Iwamoto S, Nishino I, Yamagata T.  A case of congenital fiber-type disproportion syndrome presenting dilated cardiomyopathy with ACTA1 mutation  Mol Genet Genomic Med  2022  e2008  PubMed ID: 35757965   DOI: 10.1002/mgg3.2008
20742  Sakai H, Zhou Y, Miyauchi Y, Suzuki Y, Ikeno Y, Kon R, Ikarashi N, Chiba Y, Hosoe T, Kamei J.  Increased 20S Proteasome Expression and the Effect of Bortezomib during Cisplatin-Induced Muscle Atrophy.  Biol Pharm Bull  2022  45(7):910-918  PubMed ID: 35786599   DOI: 10.1248/bpb.b22-00177
20759  Jing Z, Okubo H, Morishige JI, Xu P, Hasan N, Nagata N, Ando H.  Lenvatinib causes reduced expression of carnitine/organic cation transporter 2 and carnitine deficiency in the skeletal muscle of rats.  Toxicol Lett  2022  366:17-25  PubMed ID: 35788046   DOI: 10.1016/j.toxlet.2022.06.012
16924  Mubarok W, Elvitigala KCML, Sakai S.  Tuning Myogenesis by Controlling Gelatin Hydrogel Properties through Hydrogen Peroxide-Mediated Cross-Linking and Degradation  Gels  2022  8(6):387  PubMed ID: 35735731   DOI: 10.3390/gels8060387
20818  Nakagawara K, Takeuchi C, Ishige K.  5'-CMP and 5'-UMP promote myogenic differentiation and mitochondrial biogenesis by activating myogenin and PGC-1α in a mouse myoblast C2C12 cell line.  Biochem Biophys Rep  2022  31:101309  PubMed ID: 35865271   DOI: 10.1016/j.bbrep.2022.101309
17103  Haibo Qiao, Shoichiro Asayama  Guanidinopropyl end‐modified poly(ethylene glycol) to form highly compact plasmid DNA mono‐ion complexes by thermal treatment  Polymers for Advanced Technologies  2022  33:484-491    DOI: 10.1002/pat.5530
20832  Sakai H, Suzuki Y, Miyauchi Y, Sato F, Ando Y, Kon R, Ikarashi N, Chiba Y, Kamei J, Hosoe T.  Downregulation of Sparc-like protein 1 during cisplatin-induced inhibition of myogenic differentiation of C2C12 myoblasts.  Biochem Pharmacol  2022  204:115234  PubMed ID: 36041542   DOI: 10.1016/j.bcp.2022.115234
20904  Mu Q, Cui K, Wang ZJ, Matsuda T, Cui W, Kato H, Namiki S, Yamazaki T, Frauenlob M, Nonoyama T, Tsuda M, Tanaka S, Nakajima T, Gong JP.  Force-triggered rapid microstructure growth on hydrogel surface for on-demand functions.  Nat Commun  2022  13(1):6213  PubMed ID: 36266283   DOI: 10.1038/s41467-022-34044-8
17290  Sawada A, Yamamoto T, Sato T.  Tceal5 and Tceal7 Function in C2C12 Myogenic Differentiation via Exosomes in Fetal Bovine Serum  Int J Mol Sci  2022  23(4):2036  PubMed ID: 35216152   DOI: 10.3390/ijms23042036
17314  Ota N, Tanaka N, Sato A, Shen Y, Yalikun Y, Tanaka Y.  Microenvironmental Analysis and Control for Local Cells under Confluent Conditions via a Capillary-Based Microfluidic Device  Anal Chem  2022  Nov 16  PubMed ID: 36383697   DOI: 10.1021/acs.analchem.2c02815
20981  Enoki Y, Nagai T, Hamamura Y, Osa S, Nakamura H, Taguchi K, Watanabe H, Maruyama T, Matsumoto K.  The G protein-coupled receptor ligand apelin-13 ameliorates skeletal muscle atrophy induced by chronic kidney disease.  J Cachexia Sarcopenia Muscle  2022    PubMed ID: 36562292   DOI: 10.1002/jcsm.13159
13417  Fujita H, Mae K, Nagatani H, Horie M, Nagamori E.  Effect of hydrogen peroxide concentration on the maintenance and differentiation of cultured skeletal muscle cells.  J Biosci Bioeng  2021    PubMed ID: 33422389   DOI: 10.1016/j.jbiosc.2020.12.010
20029  Kono Y, Takegaki J, Ohba T, Matsuda K, Negoro R, Fujita S, Fujita T.  Magnetization of mesenchymal stem cells using magnetic liposomes enhances their retention and immunomodulatory efficacy in mouse inflamed skeletal muscle.  Int J Pharm  2021  596:120298  PubMed ID: 33529784   DOI: 10.1016/j.ijpharm.2021.120298
20095  Fukuoka M, Fujita H, Numao K, Nakamura Y, Shimizu H, Sekiguchi M, Hohjoh H.  MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy.  Commun Biol  2021  4(1):427  PubMed ID: 33782502   DOI: 10.1038/s42003-021-01952-2
14069  Inui T, Mei J, Imashiro C, Kurashina Y, Friend J, Takemura K.  Focused surface acoustic wave locally removes cells from culture surface  Lab Chip  2021  21(7):1299-1306  PubMed ID: 33734243   DOI: 10.1039/d0lc01293a
14070  Kondo T.  Selective eradication of pluripotent stem cells by inhibiting DHODH activity  Stem Cells  2021  39(1):33-42  PubMed ID: 33038285   DOI: 10.1002/stem.3290
14520  Sergio R. Molina Ramirez, Takahiro Yamada, Akira Funahashi, Hiroaki Onoe  Electrical Field Chamber with Dinamically Adaptable Stimuli for Myocyte Orientation During Cultivation  2021 IEEE 34th International Conference on Micro Electro Mechanical Systems (MEMS)  2021      DOI: 10.1109/mems51782.2021.9375303
20215  Diao Z, Matsui T, Funaba M.  Stimulation of myogenesis by ascorbic acid and capsaicin.  Biochem Biophys Res Commun  2021  568:83-88  PubMed ID: 34198164   DOI: 10.1016/j.bbrc.2021.06.067
20236  Ueno M, Maeshige N, Hirayama Y, Yamaguchi A, Ma X, Uemura M, Kondo H, Fujino H.  Pulsed ultrasound prevents lipopolysaccharide-induced muscle atrophy through inhibiting p38 MAPK phosphorylation in C2C12 myotubes.  Biochem Biophys Res Commun  2021  570:184-190  PubMed ID: 34293592   DOI: 10.1016/j.bbrc.2021.07.039
20251  Fujita H, Horie M, Shimizu K, Nagamori E.  Microarray profiling of gene expression in C2C12 myotubes trained by electric pulse stimulation.  J Biosci Bioeng  2021    PubMed ID: 34348874   DOI: 10.1016/j.jbiosc.2021.06.016
20252  Oki K, Yoshihara S, Urushihata N, Ghazizadeh M.  Anti-fibrotic effect of adipose-derived mesenchymal stem cell conditioned medium in muscle fibrosis.  Eur Rev Med Pharmacol Sci  2021  25(15):4953-4963  PubMed ID: 34355367   DOI: 10.26355/eurrev_202108_26452
20273  Alfarafisa NM, Kitaguchi K, Yabe T.  Diospyros kaki extract protects myoblasts from oxidative stress-induced cytotoxicity via secretions derived from intestinal epithelium.  Biosci Biotechnol Biochem  2021  85(2):430-439  PubMed ID: 33604620   DOI: 10.1093/bbb/zbaa048
20301  Sawa R, Wake I, Yamamoto Y, Okimura Y.  The involvement of Sestrin2 in the effect of IGF-I and leucine on mTROC1 activity in C2C12 and L6 myocytes.  Growth Horm IGF Res  2021  59:101406  PubMed ID: 34126555   DOI: 10.1016/j.ghir.2021.101406
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20375  Wang J, Zhang H, Kaul A, Li K, Priyandoko D, Kaul SC, Wadhwa R.  Effect of Ashwagandha Withanolides on Muscle Cell Differentiation.  Biomolecules  2021  11(10)  PubMed ID: 34680087   DOI: 10.3390/biom11101454
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16363  Keiichi Imato, Hidekazu Nakajima, Ryota Yamanaka, Naoya Takeda  Self-healing polyurethane elastomers based on charge-transfer interactions for biomedical applications  Polymer Journal  2021  53:355-362    DOI: 10.1038/s41428-020-00432-4
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11711  Toshio Norikura, Shiori Kajiya, Mami Sugawara, Miwa Kubo, Yoshiyasu Fukuyama, Shin Sato  cis-Banglene, a bangle (Zingiber purpureum)-derived bioactive compound, promotes mitochondrial biogenesis and glucose uptake by activating the IL-6/AMPK signaling pathway in C2C12 skeletal muscle cells  Journal of Functional Foods  2019      DOI: 10.1016/j.jff.2019.103632
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10417  Katsuyuki Tokinoya and Kazuhiro Takekoshi  Effect of renalase on dexamethasone-induced muscle atrophy  Int J Anal Bio-Sci  2019  7(4):68-75   
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11181  Tawara N, Yamashita S, Kawakami K, Kurashige T, Zhang Z, Tasaki M, Yamamoto Y, Nishikami T, Doki T, Zhang X, Matsuo Y, Kimura E, Tawara A, Maeda Y, Hauschka SD, Maruyama H, Ando Y.  Muscle-dominant wild-type TDP-43 expression induces myopathological changes featuring tubular aggregates and TDP-43-positive inclusions.  Exp. Neurol.  2018  309:169-180  PubMed ID: 30130494   DOI: 10.1016/j.expneurol.2018.08.006
11188  Ogiwara M, Ota W, Mizushige T, Kanamoto R, Ohinata K.  Enzymatic digest of whey protein and wheylin-1, a dipeptide released in the digest, increase insulin sensitivity in an Akt phosphorylation-dependent manner.  Food Funct  2018  9(9):4635-4641  PubMed ID: 30151525   DOI: 10.1039/c8fo00919h
11227  Sawa R, Nishida H, Yamamoto Y, Wake I, Kai N, Kikkawa U, Okimura Y.  Growth hormone and Insulin-like growth factor-I (IGF-I) modulate the expression of L-type amino acid transporters in the muscles of spontaneous dwarf rats and L6 and C2C12 myocytes.  Growth Horm. IGF Res.  2018    PubMed ID: 30273774   DOI: 10.1016/j.ghir.2018.09.002
11239  Yano H, Uchida M, Saito T, Aoki T, Kremenik MJ, Oyanagi E.  Reduction of Real-Time Imaging of M1 Macrophage Chemotaxis toward Damaged Muscle Cells is PI3K-Dependent.  Antioxidants (Basel)  2018    PubMed ID: 30297636   DOI: 10.3390/antiox7100138
11285  Ohashi M, Okubo K, Mizuno S, Yoda M, Shirasawa H, Chiba K, Horiuchi K, Matsumoto M, Nakamura M.  Granulocyte-colony stimulating factor enhances load-induced muscle hypertrophy in mice.  Biochem. Biophys. Res. Commun.  2018    PubMed ID: 30401566   DOI: 10.1016/j.bbrc.2018.10.196
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4077  Masahito Ban, Satoshi Tobea, Louie Takeuchi  Effects of diamond-like carbon thin film and wrinkle microstructure on cell proliferation  Diamond and Related Materials  2018  90:194-201    DOI: 10.1016/j.diamond.2018.10.021
4167  Asano T, Igarashi H, Ishizuka T, Yawo H.  Organelle Optogenetics: Direct Manipulation of Intracellular Ca2+ Dynamics by Light.  Front Neurosci  2018    PubMed ID: 30174581   DOI: 10.3389/fnins.2018.00561
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14902  Kanayama S, Kaito T, Kitaguchi K, Ishiguro H, Hashimoto K, Chijimatsu R, Otsuru S, Takenaka S, Makino T, Sakai Y, Myoui A, Yoshikawa H.  ONO-1301 Enhances in vitro Osteoblast Differentiation and in vivo Bone Formation Induced by Bone Morphogenetic Protein  Spine (Phila Pa 1976)   2018  43(11):E616-E624  PubMed ID: 29016438   DOI: 10.1097/BRS.0000000000002439
9859  Takase F, Inui A, Mifune Y, Sakata R, Muto T, Harada Y, Ueda Y, Kokubu T, Kurosaka M.  Effect of platelet-rich plasma on degeneration change of rotator cuff muscles: In vitro and in vivo evaluations.  J. Orthop. Res.  2017  35:1806-1815  PubMed ID: 27684960   DOI: 10.1002/jor.23451
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10095  Saito N, Kimura S, Miyamoto T, Fukushima S, Amagasa M, Shimamoto Y, Nishioka C, Okamoto S, Toda C, Washio K, Asano A, Miyoshi I, Takahashi E, Kitamura H.  Macrophage ubiquitin-specific protease 2 modifies insulin sensitivity in obese mice.  Biochem Biophys Rep  2017  9:322-329  PubMed ID: 28956020   DOI: 10.1016/j.bbrep.2017.01.009
10179  Ono A, Ito A, Sato T, Yamaguchi M, Suzuki T, Kawabe Y, Kamihira M.  Hypoxia-responsive transgene expression system using RTP801 promoter and synthetic transactivator fused with oxygen-dependent degradation domain.  J. Biosci. Bioeng.  2017  124:115-124  PubMed ID: 28284789   DOI: 10.1016/j.jbiosc.2017.02.012
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10375  Kurashina Y, Hirano M, Imashiro C, Totani K, Komotori J, Takemura K.  Enzyme-free cell detachment mediated by resonance vibration with temperature modulation.  Biotechnol. Bioeng.  2017  114:2279-2288  PubMed ID: 28627736   DOI: 10.1002/bit.26361
10413  Yoshida K, Imamura CK, Hara K, Mochizuki M, Tanigawara Y.  Effect of everolimus on the glucose metabolic pathway in mouse skeletal muscle cells (C2C12).  Metabolomics  2017  13:98  PubMed ID: 28781589   DOI: 10.1007/s11306-017-1236-5
10442  Ono Y, Sakamoto K.  Lipopolysaccharide inhibits myogenic differentiation of C2C12 myoblasts through the Toll-like receptor 4-nuclear factor-κB signaling pathway and myoblast-derived tumor necrosis factor-α.  PLoS ONE  2017  12:e0182040  PubMed ID: 28742154   DOI: 10.1371/journal.pone.0182040
10462  Ogawa M, Kitano T, Kawata N, Sugihira T, Kitakaze T, Harada N, Yamaji R.  Daidzein down-regulates ubiquitin-specific protease 19 expression through estrogen receptor β and increases skeletal muscle mass in young female mice.  J. Nutr. Biochem.  2017  49:63-70  PubMed ID: 28886438   DOI: 10.1016/j.jnutbio.2017.07.017
10476  Minami K, Mori T, Nakanishi W, Shigi N, Nakanishi J, Hill JP, Komiyama M, Ariga K.  Suppression of Myogenic Differentiation of Mammalian Cells Caused by Fluidity of a Liquid-Liquid Interface.  ACS Appl Mater Interfaces  2017  9:30553-30560  PubMed ID: 28836758   DOI: 10.1021/acsami.7b11445
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10479  Yamamoto Y, Sawa R, Wake I, Morimoto A, Okimura Y.  Glucose-mediated inactivation of AMP-activated protein kinase reduces the levels of L-type amino acid transporter 1 mRNA in C2C12 cells.  Nutr Res  2017  47:13-20  PubMed ID: 29241574   DOI: 10.1016/j.nutres.2017.08.003
10511  Okutani C, Wagatsuma A, Mabuchi K, Hoshino T.  Directed cell migration in co-cultures by topographic curvature for heterogeneous tissue engineering.  Conf Proc IEEE Eng Med Biol Soc  2017  2017:1607-1610  PubMed ID: 29060190   DOI: 10.1109/EMBC.2017.8037146
10536  Fujiwara Y, Tsukahara C, Ikeda N, Sone Y, Ishikawa T, Ichi I, Koike T, Aoki Y.  Oleuropein improves insulin resistance in skeletal muscle by promoting the translocation of GLUT4.  J Clin Biochem Nutr  2017  61:196-202  PubMed ID: 29203961   DOI: 10.3164/jcbn.16-120
10942  Takayuki Hoshino ; Moto Yoshioka ; Akira Wagatsuma ; Hiroki Miyazako ; Kunihiko Mabuchi  Fine virtual cathode display for biomolecules control and cell nano surgery  IEEE Xplore  2017      DOI: 10.1109/MEMSYS.2017.7863471
10943    On-chip internalization process of an intracellular nanobot into a single cell  IEEE Xplore  2017      DOI: 10.1109/MEMSYS.2017.7863473
10963    Cell descent caused by boundary curvature of a high topographical structure for a device that changes cell density  Japanese Journal of Applied Physics  2017  56:06GM03    DOI: 10.7567/JJAP.56.06GM03
12216  Hideo Saito, Koshi N Kishimoto, Yu Mori, Hiroshi Okuno, Masahiko Tanaka, Eiji Itoi  A vitamin D analogue, eldecalcitol, enhances expression of fast myosin heavy chain subtypes in differentiated C2C12 myoblasts  J Orthop Sci  2017  22(2):345-350  PubMed ID: 28017710   DOI: 10.1016/j.jos.2016.12.005
14209  Dynamic Mechano-Regulation of Myoblast Cells on Supramolecular Hydrogels Cross-Linked by Reversible Host-Guest Interactions  Dynamic Mechano-Regulation of Myoblast Cells on Supramolecular Hydrogels Cross-Linked by Reversible Host-Guest Interactions  Sci Rep  2017  7(1):7660  PubMed ID: 28794475   DOI: 10.1038/s41598-017-07934-x
14370  Tanaka S, Ono Y, Sakamoto K.  DCEBIO facilitates myogenic differentiation via intermediate conductance Ca 2+ activated K + channel activation in C2C12 myoblasts  J Pharmacol Sci  2017  133(4):276-279  PubMed ID: 28302447   DOI: 10.1016/j.jphs.2017.02.005
14492  Ikeda K, Ito A, Sato M, Kanno S, Kawabe Y, Kamihira M.  Effects of heat stimulation and l-ascorbic acid 2-phosphate supplementation on myogenic differentiation of artificial skeletal muscle tissue constructs  J Tissue Eng Regen Med  2017  11(5):1322-1331  PubMed ID: 26033935   DOI: 10.1002/term.2030
14634  Yuto Nishidono, Takashi Fujita, Akira Kawanami, Mikio Nishizawa, Ken Tanaka  Identification of PGC-1α activating constituents in Zingiberaceous crude drugs  Fitoterapia  2017  122:40-44  PubMed ID: 28827002   DOI: 10.1016/j.fitote.2017.08.007
14640  Fujii C, Miyashita K, Mitsuishi M, Sato M, Fujii K, Inoue H, Hagiwara A, Endo S, Uto A, Ryuzaki M, Nakajima M, Tanaka T, Tamaki M, Muraki A, Kawai T, Itoh H.  Treatment of sarcopenia and glucose intolerance through mitochondri  Sci Rep  2017  7(1):4013  PubMed ID: 28638045   DOI: 10.1038/s41598-017-03917-0
14764  Yasuko Yoshida, Takehito Sugasawa, Katsuyuki Tokinoya, Shunji Namba, Kazuhiro Takekoshi  Epinephrine upregulates renalase expression in cultured C2C12 muscle cells  Int J Anal Bio-Sci  2017  5:61-65   
7146  Toda K, Takeda S, Hitoe S, Nakamura S, Matsuda H, Shimoda H.  Enhancement of energy production by black ginger extract containing polymethoxy flavonoids in myocytes through improving glucose, lactic acid and lipid metabolism.  J Nat Med  2016  70:163-72  PubMed ID: 26581843   DOI: 10.1007/s11418-015-0948-y
7184  Nozaki T, Nikai S, Okabe R, Nagahama K, Eto N.  A novel in vitro model of sarcopenia using BubR1 hypomorphic C2C12 myoblasts.  Cytotechnology  2016  68:1705-15  PubMed ID: 26464273   DOI: 10.1007/s10616-015-9920-7
9797  Enoki Y, Watanabe H, Arake R, Sugimoto R, Imafuku T, Tominaga Y, Ishima Y, Kotani S, Nakajima M, Tanaka M, Matsushita K, Fukagawa M, Otagiri M, Maruyama T.  Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1.  Sci Rep  2016  6:32084  PubMed ID: 27549031   DOI: 10.1038/srep32084
9803  Kitakaze T, Sakamoto T, Kitano T, Inoue N, Sugihara F, Harada N, Yamaji R.  The collagen derived dipeptide hydroxyprolyl-glycine promotes C2C12 myoblast differentiation and myotube hypertrophy.  Biochem. Biophys. Res. Commun.  2016  478:1292-7  PubMed ID: 27553280   DOI: 10.1016/j.bbrc.2016.08.114
10874    Electron beam induced fine virtual electrode for mechanical strain microscopy of living cell  Sensors and Actuators B: Chemical   2016  236, 659-667    DOI: 10.1016/j.snb.2016.06.023
10886    Improvement of Mitochondrial Function and Lipid Utilization by 3,5-dihydroxy-4-methoxybenzyl Alcohol, an Oyster-derived polyphenol, in Oleate-loaded C2C12 Myotubes  Journal of Food and Nutrition Research  2016  4, 498    DOI: 10.12691/jfnr-4-8-3
12906  Shiozaki K, Harasaki Y, Fukuda M, Yoshinaga A, Ryuzono S, Chigwechokha PK, Komatsu M, Miyagi T.  Positive regulation of myoblast differentiation by medaka Neu3b sialidase through gangliosides desialylation  Biochimie  2016  123:65-72  PubMed ID: 26805383   DOI: 10.1016/j.biochi.2016.01.010
12926  Ikeda K, Ito A, Sato M, Kawabe Y, Kamihira M.  Improved contractile force generation of tissue-engineered skeletal muscle constructs by IGF-I and Bcl-2 gene transfer with electrical pulse stimulation  Regen Ther  2016  3:38-44  PubMed ID: 31245471   DOI: 10.1016/j.reth.2015.12.004
12932  Hu X, Cheng D, Zhang Z.  Antidiabetic activity of Helicteres angustifolia root  Pharm Biol  2016  54(6):938-44  PubMed ID: 26866383   DOI: 10.3109/13880209.2015.1077871
12944  Futawaka K, Tagami T, Fukuda Y, Koyama R, Nushida A, Nezu S, Imamoto M, Kasahara M, Moriyama K.  Growth hormone regulates the expression of UCP2 in myocytes  Growth Horm IGF Res  2016  29:57-62  PubMed ID: 27150070   DOI: 10.1016/j.ghir.2016.04.005
12750  Nakatani M, Ito J, Koyama R, Iijima M, Yoshimoto N, Niimi T, Kuroda S, Maturana AD.  Scaffold protein enigma homolog 1 overcomes the repression of myogenesis activation by inhibitor of DNA binding 2  Biochem Biophys Res Commun  2016  474(2):413-420  PubMed ID: 27114303   DOI: 10.1016/j.bbrc.2016.04.119
13457  Hu XS, Cheng DL, Li KJ, Wang LB, Yang X, Sun S, Wang YP, Li SH, Lei ZF, Zhang ZY.  Glucose consumption and alpha-glucosidase inhibitory activities of aqueous root extract of Helicteres angustifolia  Eur Rev Med Pharmacol Sci  2016  20(7):1423-9.  PubMed ID: 27097967  
13966  Sato H, Funaki A, Kimura Y, Sumitomo M, Yoshida H, Fukata H, Ueno K.  Ethanol extract of Cyclolepis genistoides D. Don (palo azul) induces formation of myotubes, which involves differentiation of C2C12 myoblast cells  Nutr Res  2016  36(7):731-41  PubMed ID: 27262535   DOI: 10.1016/j.nutres.2016.02.011
14042  Shirai M, Yamamoto R, Chiba T, Komatsu K, Shimoda S, Yamakoshi Y, Oida S, Ohkubo C.  Bone augmentation around a dental implant using demineralized bone sheet containing biologically active substances  Dent Mater J  2016  35(3):470-8  PubMed ID: 27252004   DOI: 10.4012/dmj.2016-026
14096  Takeda N, Tamura K, Mineguchi R, Ishikawa Y, Haraguchi Y, Shimizu T, Hara Y.  In situ cross-linked electrospun fiber scaffold of collagen for fabricating cell-dense muscle tissue  J Artif Organs  2016  19(2):141-8  PubMed ID: 26472433   DOI: 10.1007/s10047-015-0871-8
14102  Warita K, Oshima N, Takeda-Okuda N, Tamura JI, Hosaka YZ.  Degree of Suppression of Mouse Myoblast Cell Line C₂C 12 Differentiation Varies According to Chondroitin Sulfate Subtype  Mar Drugs  2016  14(10):193  PubMed ID: 27775651   DOI: 10.3390/md14100193
14115  Onishi Y, Fukasawa K, Ozaki K, Iezaki T, Yoneda Y, Hinoi E.  GDF1 is a novel mediator of macrophage infiltration in brown adipose tissue of obese mice  Biochem Biophys Rep  2016  5: 216–223.  PubMed ID: 28955827   DOI: 10.1016/j.bbrep.2015.12.008
15304  Tanahashi H, Tian QB, Hara Y, Sakagami H, Endo S, Suzuki T.  Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance  Sci Rep  2016  6:20241  PubMed ID: 26847765   DOI: 10.1038/srep20241
7142  Washio K, Kobayashi M, Saito N, Amagasa M, Kitamura H.  Propolis Ethanol Extract Stimulates Cytokine and Chemokine Production through NF-κB Activation in C2C12 Myoblasts.  Evid Based Complement Alternat Med  2015  2015:349751  PubMed ID: 26604971   DOI: 10.1155/2015/349751
7249  Oh S, Kato M, Zhang C, Guo Y, Beachy PA.  A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response.  PLoS ONE  2015  10:e0135804  PubMed ID: 26271100   DOI: 10.1371/journal.pone.0135804
7250  Otani M, Furukawa S, Wakisaka S, Maeda T.  A novel adipokine C1q/TNF-related protein 3 is expressed in developing skeletal muscle and controls myoblast proliferation and differentiation.  Mol. Cell. Biochem.  2015  409:271-82  PubMed ID: 26272338   DOI: 10.1007/s11010-015-2531-y
7284  Ayabe T, Mizushige T, Ota W, Kawabata F, Hayamizu K, Han L, Tsuji T, Kanamoto R, Ohinata K.  A novel Alaska pollack-derived peptide, which increases glucose uptake in skeletal muscle cells, lowers the blood glucose level in diabetic mice.  Food Funct  2015  6:2749-57  PubMed ID: 26152190   DOI: 10.1039/c5fo00401b
7311  Ichimura T, Chiu LD, Fujita K, Machiyama H, Kawata S, Watanabe TM, Fujita H.  Visualizing the appearance and disappearance of the attractor of differentiation using Raman spectral imaging.  Sci Rep  2015  5:11358  PubMed ID: 26079396   DOI: 10.1038/srep11358
7323  Minami K, Kasuya Y, Yamazaki T, Ji Q, Nakanishi W, Hill JP, Sakai H, Ariga K.  Highly Ordered 1D Fullerene Crystals for Concurrent Control of Macroscopic Cellular Orientation and Differentiation toward Large-Scale Tissue Engineering.  Adv. Mater. Weinheim  2015  27:4020-6  PubMed ID: 26033774   DOI: 10.1002/adma.201501690
7416  Wu S, Zhang J, Huang C, Jia H, Wang Y, Xu Z, Yang L, Miyagishi M, Kasim V.  Prolyl hydroxylase domain-2 silencing induced by hydrodynamic limb vein injection enhances vascular regeneration in critical limb ischemia mice through activation of multiple genes.  Curr Gene Ther  2015  15:313-25  PubMed ID: 25832622   DOI: 10.2174/156652321503150329003735
7454  Takeda I, Kawanabe M, Kaneko A.  Autonomous patterning of cells on microstructured fine particles.  Mater Sci Eng C Mater Biol Appl  2015  50:173-8  PubMed ID: 25746259   DOI: 10.1016/j.msec.2015.02.010
7465  Takemoto K, Ishihara S, Mizutani T, Kawabata K, Haga H.  Compressive stress induces dephosphorylation of the myosin regulatory light chain via RhoA phosphorylation by the adenylyl cyclase/protein kinase A signaling pathway.  PLoS ONE  2015  10:e0117937  PubMed ID: 25734240   DOI: 10.1371/journal.pone.0117937
7472  Takeda T, Tsuiji K, Li B, Tadakawa M, Yaegashi N.  Proliferative effect of Hachimijiogan, a Japanese herbal medicine, in C2C12 skeletal muscle cells.  Clin Interv Aging  2015  10:445-51  PubMed ID: 25709418   DOI: 10.2147/CIA.S75945
7483  Nakanishi K, Kakiguchi K, Yonemura S, Nakano A, Morishima N.  Transient Ca2+ depletion from the endoplasmic reticulum is critical for skeletal myoblast differentiation.  FASEB J.  2015  29:2137-49  PubMed ID: 25678623   DOI: 10.1096/fj.14-261529
7488  Asano T, Ishizuka T, Morishima K, Yawo H.  Optogenetic induction of contractile ability in immature C2C12 myotubes.  Sci Rep  2015  5:8317  PubMed ID: 25661648   DOI: 10.1038/srep08317
7509  Kaneko K, Higuchi C, Kunugiza Y, Yoshida K, Sakai T, Yoshikawa H, Nakata K.  Hyaluronan inhibits BMP-induced osteoblast differentiation.  FEBS Lett.  2015  589:447-54  PubMed ID: 25592835   DOI: 10.1016/j.febslet.2014.12.031
7576  Yuki Igaki, Fumio Mizutani, Tomoyuki Yasukawa  Oxygen consumption of contractile C2C12 myotubes investigated by scanning electrochemical microscopy.  Chemistry Letters  2015  44:1031-1032    DOI: 10.1246/cl.150371
5450  Sugita S1, Hosaka Y2, Okada K1, Mori D3, Yano F4, Kobayashi H1, Taniguchi Y1, Mori Y1, Okuma T1, Chang SH1, Kawata M1, Taketomi S1, Chikuda H, Akiyama H, Kageyama R, Chung UI, Tanaka S, Kawaguchi H, Ohba S, Saito T.  Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2.  Proc Natl Acad Sci U S A  2015  112(10):3080-5  PubMed ID: 25733872   DOI: 10.1073/pnas.1419699112
9392  Masahiko Terauchi, Go Ikeda, Kei Nishida, Atsushi Tamura, Satoshi Yamaguchi, Kiyoshi Harada, Nobuhiko Yui  Supramolecular Polyelectrolyte Complexes of Bone Morphogenetic Protein-2 With Sulfonated Polyrotaxanes to Induce Enhanced Osteogenic Differentiation  Macromol Biosci  2015  15(7):953-64  PubMed ID: 25810046   DOI: 10.1002/mabi.201500032
14137  小川真弘、河田夏初、山地亮一  速筋における大豆イソフラボンによるインスリン様成長因子の発現調節機構に関する研究  大豆たん白質研究  2015  18   
14989  Horie M, Warabi E, Komine S, Oh S, Shoda J.  Cytoprotective Role of Nrf2 in Electrical Pulse Stimulated C2C12 Myotube  PLoS One  2015  10(12):e0144835  PubMed ID: 26658309   DOI: 10.1371/journal.pone.0144835
15022  Ogawa M, Kitakaze T, Harada N, Yamaji R.  Female-specific regulation of skeletal muscle mass by USP19 in young mice  J Endocrinol  2015  225(3):135-45  PubMed ID: 25901042   DOI: 10.1530/JOE-15-0128
15062  Park E, Cho HB, Takimoto K.  Effective gene delivery into adipose-derived stem cells: transfection of cells in suspension with the use of a nuclear localization signal peptide-conjugated polyethylenimine  Cytotherapy  2015  17(5):536-42  PubMed ID: 25618562   DOI: 10.1016/j.jcyt.2014.11.008
10473  Ohsawa Y, Takayama K, Nishimatsu S, Okada T, Fujino M, Fukai Y, Murakami T, Hagiwara H, Itoh F, Tsuchida K, Hayashi Y, Sunada Y.  The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy  PLoS One  2015  10(7):e0133713  PubMed ID: 26226340   DOI: 10.1371/journal.pone.0133713
15432  Yoshino M, Naka A, Sakamoto Y, Shibasaki A, Toh M, Tsukamoto S, Kondo K, Iida K.  Dietary isoflavone daidzein promotes Tfam expression that increases mitochondrial biogenesis in C2C12 muscle cells  J Nutr Biochem  2015  26(11):1193-9  PubMed ID: 26166229   DOI: 10.1016/j.jnutbio.2015.05.010
15447  Tamaki M, Hagiwara A, Miyashita K, Wakino S, Inoue H, Fujii K, Fujii C, Sato M, Mitsuishi M, Muraki A, Hayashi K, Doi T, Itoh H.  Improvement of Physical Decline Through Combined Effects of Muscle Enhancement and Mitochondrial Activation by a Gastric Hormone Ghrelin in Male 5/6Nx CKD Model Mice  Endocrinology  2015  156(10):3638-48  PubMed ID: 26241123   DOI: 10.1210/en.2015-1353
6677  Katase N, Terada K, Suzuki T, Nishimatsu S, Nohno T.  miR-487b, miR-3963 and miR-6412 delay myogenic differentiation in mouse myoblast-derived C2C12 cells  BMC Cell Biol  2015  16:13  PubMed ID: 25925429   DOI: 10.1186/s12860-015-0061-9
5402  Takara Tanaka, Noriko Hattori-Aramaki, Ayano Sunohara, Keisuke Okabe, Yoshiaki Sakamoto, Hiroko Ochiai, Ruka Hayashi, and Kazuo Kishi  Alignment of Skeletal Muscle Cells Cultured in Collagen Gel by Mechanical and Electrical Stimulation  International Journal of Tissue Engineering  2014  Article ID 621529, 5 pages    DOI: 10.1155/2014/621529
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15905  Maeda A, Kai K, Ishii M, Ishii T, Akagawa M.  Safranal, a novel protein tyrosine phosphatase 1B inhibitor, activates insulin signaling in C2C12 myotubes and improves glucose tolerance in diabetic KK-Ay mice  Mol Nutr Food Res  2014  58(6):1177-89  PubMed ID: 24668740   DOI: 10.1002/mnfr.201300675
15906  Sakagami H, Makino Y, Mizumoto K, Isoe T, Takeda Y, Watanabe J, Fujita Y, Takiyama Y, Abiko A, Haneda M.  Loss of HIF-1α impairs GLUT4 translocation and glucose uptake by the skeletal muscle cells  Am J Physiol Endocrinol Metab  2014  306(9):E1065-76.  PubMed ID: 24619881   DOI: 10.1152/ajpendo.00597.2012
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15937  Ito-Nagahata T, Kurihara C, Hasebe M, Ishii A, Yamashita K, Iwabuchi M, Sonoda M, Fukuhara K, Sawada R, Matsuoka A, Fujiwara Y.  Stilbene analogs of resveratrol improve insulin resistance through activation of AMPK  Biosci Biotechnol Biochem  2013  1229-35  PubMed ID: 23748787   DOI: 10.1271/bbb.121000
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15763  Tadahiro Sunagawa, Kenji Watanabe, Yusuke Ozawa, Shohei Nakashima, Tomomasa Kanda, Motoyuki Tagashira, Manabu Sami, Takao Kaneko, Shoichi Tahara, Haruaki Nakaya, Takuji Shirasawa, Takahiko Shimizu  Apple Polyphenols Regulate Mitochondrial Superoxide Generation and Extend Survival in a Mouse Model of Dilated Cardiomyopathy  International Journal of Life Science and Medical Research  2012  2:46-51    DOI: 10.5963/lsmr0203003
15969  Hidetaka Uno, Zhi-hong Wang, Noriko Takada, Toru Ishizuka, Hiromu Yawo, Tsuneo Urisu  Channelrhodopsin as a Noble Biomaterial Useful for the Operation and Performance Test of the Ionchannel Devices  MATERIALS TRANSACTIONS  2012  53:1305-1309    DOI: 10.2320/matertrans.n-m2012814
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5662  村上 祐子, 足立 浩章, 田中 浩, 八代 洋一, 中田 悟  眼輪筋に着目した目もとの加齢変化のメカニズム解析  日本化粧品技術者会誌  2015  49:36-41    DOI: 10.5107/sccj.49.36



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