検索画面
細胞材料開発室サイト

戻る 戻る
細胞番号 : 細胞名
RCB0806 : Jurkat  update : 2021/02/26
細胞特性(Comment:英)Human T cell line, the same patient as JM. IL-2 productivity of this line was undetermined.
細胞特性(日)ヒトT細胞株。IL-2産生能があるとされているが、この株では未確認。マイコプラズマ汚染除去処理済。
細胞特性(寄託者記述:英)
細胞特性(寄託者記述:日)
使用条件(英)There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
使用条件(日)基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。
備考(英)
備考(日)
提供申込書類(英) Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず(cellbank.brc@riken.jp)までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 Todokoro, Kazuo
寄託日 1992
動物種 _human < Mammals
属名 Homo
種名 sapiens
性別 Male
14 years
採取組織 blood
病名 acute T cell leukemia
細胞分類 cancer
メモ_1 Mycoplasma was eliminated with MC-210.
細胞寿命 infinite
細胞形態 lymphocyte-like
細胞培養・検査情報
寄託時情報
ロット情報
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Suspension cells
培地 RPMI1640 + 10% FBS
抗生物質 Free
継代方法 dilution
継代密度 1 : 10 split
継代・培地交換頻度 Subculture : 2 times/week
培養最適温度 37 ℃
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
個体識別検査 OK
ウィルス(HIV) (-)
ウィルス(HTLV-1) (-)
アイソザイム検査 LD, NP
染色体検査 Lot.1 : 42-92(50) : 42(2),43(1),44(6),45(21),46(14),47(5)/
画像情報
寄託時情報
ロット情報
その他の細胞情報 寄託時情報ロット情報
Jurkat_CD3.pdf
文献情報 Reference(英) 7件
Reference(日) 0件
利用者成果(英) 43件
利用者成果(日) 0件

トップへページトップへ
Reference(英)
1640  LaGree KA, Lee AT, Stetten G, Strauss PR.  The human Jurkat (FHCRC-11) cell line is heterogeneous in ploidy and cell size and releases detergent-soluble DNA.  Exp Hematol  1988  16(8):686-90  PubMed ID: 3165345
4749  Wendler I1, Jentsch KD, Schneider J, Hunsmann G.  Efficient replication of HTLV-III and STLV-IIImac in human Jurkat cells.  Med Microbiol Immunol  1987  176(5):273-80  PubMed ID: 2443825
1685  Weiss A, Wiskocil RL, Stobo JD.  The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level.  J Immunol  1984  133(1):123-8  PubMed ID: 6327821
1638  Pawelec G, Borowitz A, Krammer PH, Wernet P.  Constitutive interleukin 2 production by the JURKAT human leukemic T cell line.  Eur J Immunol  1982  12(5):387-92  PubMed ID: 6980126
1637  Kahle P, Wernet P, Rehbein A, Kumbier I, Pawelec G.  Cloning of functional human T lymphocytes by limiting dilution: impact of filler cells and interleukin 2 sources on cloning efficiencies.  Scand J Immunol  1981  14(5):493-502  PubMed ID: 6278580
515  Gillis S, Watson J.  Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line.  J Exp Med  1980  152(6):1709-19  PubMed ID: 6778951
902  Schneider U, Schwenk HU, Bornkamm G.  Characterization of EBV-genome negative "null" and "T" cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma.  Int J Cancer  1977  19(5):621-6  PubMed ID: 68013

トップへページトップへ
Reference(日)

トップへページトップへ
利用者成果(英)
13156  Aota K, Yamanoi T, Kani K, Ono S, Momota Y, Azuma M.  Inhibition of JAK-STAT Signaling by Baricitinib Reduces Interferon-γ-Induced CXCL10 Production in Human Salivary Gland Ductal Cells.  Inflammation  2021    PubMed ID: 32772240
13052  Kawai S, Suzuki M, Arimoto S, Korenaga T, Yasukawa T.  Determination of membrane capacitance and cytoplasm conductivity by simultaneous electrorotation.  Analyst  2020    PubMed ID: 32462157
13322  Bakalova R, Semkova S, Ivanova D, Zhelev Z, Miller T, Takeshima T, Shibata S, Lazarova D, Aoki I, Higashi T.  Selective Targeting of Cancerous Mitochondria and Suppression of Tumor Growth Using Redox-Active Treatment Adjuvant.  Oxid Med Cell Longev  2020    PubMed ID: 33204397
10599  Yoshimi Utaka, Gengo Kashiwazaki, Sachiko Tajima, Yuko Fujiwara, Keitaro Sumi, Tomohiro Itoh, Takashi Kitayama  Antiproliferative effects of zerumbone-pendant derivatives on human T-cell lymphoid cell line Jurkat cells  Tetrahedron  2019  75:1343-1350 
10946  Tsubasa Koga, Keiko Morotomi-Yano, Takashi Sakugawa, Hisato Saitoh, Ken-Ichi Yano  Nanosecond pulsed electric fields induce extracellular release of chromosomal DNA and histone citrullination in neutrophil-differentiated HL-60 cells  Sci Rep  2019  9(1):8451  PubMed ID: 31186478
12485  Sharma N, Baek K, Shimokawa N, Takagi M.  Effect of temperature on raft-dependent endocytic cluster formation during activation of Jurkat T cells by concanavalin A  J Biosci Bioeng  2019  127(4):479-485  PubMed ID: 30355461
7069  Kataoka K, Shiraishi Y, Takeda Y, Sakata S, Matsumoto M, Nagano S, Maeda T, Nagata Y, Kitanaka A, Mizuno S, Tanaka H, Chiba K, Ito S, Watatani Y, Kakiuchi N, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Itonaga H, Imaizumi Y, Totoki Y, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Masuda K, Minato N, Kashiwase K, Izutsu K, Takaori-Kondo A, Miyazaki Y, Takahashi S, Shibata T, Kawamoto H, Akatsuka Y, Shimoda K, Takeuchi K, Seya T, Miyano S, Ogawa S.  Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.  Nature  2016  534:402-6  PubMed ID: 27281199
9159  Tsukasa Nakanishi, Yuan Song, Cuiying He 1, Duo Wang, Kentaro Morita, Junichi Tsukada, Tamotsu Kanazawa, Yasuhiro Yoshida  Autophagy Is Associated With Cucurbitacin D-induced Apoptosis in Human T Cell Leukemia Cells  Med Oncol  2016  33 (4), 30  PubMed ID: 26913856
12962  Hayashi K, Ouchi M, Endou H, Anzai N.  HOXB9 acts as a negative regulator of activated human T cells in response to amino acid deficiency  Immunol Cell Biol  2016  94(6):612-7.  PubMed ID: 26926958
7244  Ishii T, Sato K, Kakumoto T, Miura S, Touhara K, Takeuchi S, Nakata T.  Light generation of intracellular Ca(2+) signals by a genetically encoded protein BACCS.  Nat Commun  2015  6:8021  PubMed ID: 26282514
7821  Qi H, Takano H, Kato Y, Wu Q, Ogata C, Zhu B, Murata Y, Nakamura Y.  Hydrogen [corrected] peroxide-dependent photocytotoxicity by phloxine B, a xanthene-type food colorant.  Biochim. Biophys. Acta  2011  1810:704-12  PubMed ID: 21565256
7874  Wang F, Fang W, Zhang MR, Zhao M, Liu B, Wang Z, Hua Z, Yang M, Kumata K, Hatori A, Yamasaki T, Yanamoto K, Suzuki K.  Evaluation of chemotherapy response in VX2 rabbit lung cancer with 18F-labeled C2A domain of synaptotagmin I.  J. Nucl. Med.  2011  52:592-9  PubMed ID: 21421722
6237  Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S.  HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7.  Atherosclerosis   2011  217(2):407-14  PubMed ID: 21762915
8582  Zhang G, Wu H, Zhu B, Shimoishi Y, Nakamura Y, Murata Y.  Induction of apoptosis by beta-carotene and dimethyl tetrasulfide assisted by UVA irradiation in HL-60 cells.  Biosci. Biotechnol. Biochem.  2009  73:1014-20  PubMed ID: 19420723
8667  Kobayashi K, Yasuda Y, Shintani Y, Sumitomo T, Saga T, Kimura M, Yamamoto A, Mori T, Maeda A, Yamaguchi Y, Morita A.  The development of a filter to enhance the efficacy and safety of excimer light (308 nm) therapy.  Photodermatol Photoimmunol Photomed  2009  25:30-6  PubMed ID: 19152513
9078  Yorihiro Nishimura, Masayuki Shimojima, Yoshio Tano, Tatsuo Miyamura, Takaji Wakita, Hiroyuki Shimizu  Human P-selectin Glycoprotein ligand-1 Is a Functional Receptor for Enterovirus 71  Nat Med  2009  15 (7), 794-7  PubMed ID: 19543284
8761  Okamura A, Hagiwara T, Yamagami S, Yamaguchi M, Shinbo T, Kanamori T, Kondo S, Miwa K, Itagaki I.  Effective cell separation utilizing poly(N-isopropylacrylamide)-grafted polypropylene membrane containing adsorbed antibody.  J. Biosci. Bioeng.  2008  105:221-5  PubMed ID: 18397772
9059  Y-C Jung, E Mizuki, T Akao, J-C Côté  Isolation and Characterization of a Novel Bacillus Thuringiensis Strain Expressing a Novel Crystal Protein With Cytocidal Activity Against Human Cancer Cells  J Appl Microbiol  2007  103 (1), 65-79  PubMed ID: 17584453
3413  Yamashita, Satoko, Katayama, Hideki, Saitoh, Hiroyuki, Akao, Tetsuyuki, Park, Yu Shin, Mizuki, Eiichi, Ohba, Michio, Ito, Akio  Typical Three-Domain Cry Proteins of Bacillus thuringiensis Strain A1462 Exhibit Cytocidal Activity on Limited Human Cancer Cells.  J Biochem  2005  138:663-72  PubMed ID: 16428294
2892  Katayama H, Yokota H, Akao T, Nakamura O, Ohba M, Mekada E, Mizuki E  Parasporin-1, a novel cytotoxic protein to human cells from non-insecticidal parasporal inclusions of Bacillus thuringiensis  J Biochem (Tokyo)  2005  137:17-25  PubMed ID: 15713879
2875  Miyoshi N, Naniwa K, Kumagai T, Uchida K, Osawa T, Nakamura Y.  Alpha-tocopherol-mediated caspase-3 up-regulation enhances susceptibility to apoptotic stimuli.  Biochem Biophys Res Commun  2005  334(2):466-73  PubMed ID: 16009347
2891  Kishimoto S, Muramatsu M, Gokoh M, Oka S, Waku K, Sugiura T.  Endogenous cannabinoid receptor ligand induces the migration of human natural killer cells.  J Biochem  2005  137(2):217-23  PubMed ID: 15749836
2896  Yamanaka M, Eda S, Beppu M.  Carbohydrate chains and phosphatidylserine successively work as signals for apoptotic cell removal.  Biochem Biophys Res Commun  2005  328(1):273-80  PubMed ID: 15670780
3349  Hirano K, Miki Y, Hirai Y, Sato R, Itoh T, Hayashi A, Yamanaka M, Eda S, Beppu M.  A multifunctional shuttling protein nucleolin is a macrophage receptor for apoptotic cells.  J Biol Chem  2005  280(47):39284-93  PubMed ID: 16135517
3387  Ogawa Y, Morikawa N, Ohkubo-Suzuki A, Miyoshi S, Arakawa H, Kita Y, Nishimura S.  An epoch-making application of discharge plasma phenomenon to gene-transfer.  Biotechnol Bioeng  2005  92(7):865-70  PubMed ID: 16170826
9048  Shiro Okumura, Hiroyuki Saitoh, Tomoyuki Ishikawa, Naoya Wasano, Satoko Yamashita, Ken-Ichi Kusumoto, Tetsuyuki Akao, Eiichi Mizuki, Michio Ohba, Kuniyo Inouye  Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines  J Agric Food Chem  2005  53 (16), 6313-8  PubMed ID: 16076112
4437  Hamasu T, Inanami O, Tsujitani M, Yokoyama K, Takahashi E, Kashiwakura I, Kuwabara M.  Post-irradiation hypoxic incubation of X-irradiated MOLT-4 cells reduces apoptotic cell death by changing the intracellular redox state and modulating SAPK/JNK pathways  Apoptosis  2005  10(3):557-67  PubMed ID: 15909118
2894  Ito, Akio, Sasaguri, Yasuyuki, Kitada, Sakae, Kusaka, Yoshitomo, Kuwano, Kyoko, Masutomi, Kenjiro, Mizuki, Eiichi, Akao, Tetsuyuki, Ohba, Michio  A Bacillus thuringiensis crystal protein with selective cytocidal action to human cells.  J Biol Chem  2004  279:21282-6  PubMed ID: 15026424
3403  Ozaki, Kouichi, Inoue, Katsumi, Sato, Hiroshi, Iida, Aritoshi, Ohnishi, Yozo, Sekine, Akihiro, Sato, Hideyuki, Odashiro, Keita, Nobuyoshi, Masakiyo, Hori, Masatsugu, Nakamura, Yusuke, Tanaka, Toshihiro  Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.  Nature  2004  429:72-5  PubMed ID: 15129282
3340  Watanabe, Dai, Ezoe, Sachiko, Fujimoto, Minoru, Kimura, Akihiro, Saito, Yoshiyuki, Nagai, Hisaki, Tachibana, Isao, Matsumura, Itaru, Tanaka, Toshio, Kanegane, Hirokazu, Miyawaki, Toshio, Emi, Mitsuru, Kanakura, Yuzuru, Kawase, Ichiro, Naka, Tetsuji, Kishimoto, Tadamitsu  Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines.  Br J Haematol  2004  126:726-35  PubMed ID: 15327527
2863  Watanabe M, Kitano T, Kondo T, Yabu T, Taguchi Y, Tashima M, Umehara H, Domae N, Uchiyama T, Okazaki T.  Increase of nuclear ceramide through caspase-3-dependent regulation of the "sphingomyelin cycle" in Fas-induced apoptosis.  Cancer Res  2004  64(3):1000-7  PubMed ID: 14871831
2884  Miyoshi N, Uchida K, Osawa T, Nakamura Y.  A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation.  Cancer Res  2004  64(6):2134-42  PubMed ID: 15026354
2912  Eda S, Yamanaka M, Beppu M.  Carbohydrate-mediated phagocytic recognition of early apoptotic cells undergoing transient capping of CD43 glycoprotein.  J Biol Chem  2004  279(7):5967-74  PubMed ID: 14613931
13799  Enomoto M, Endo D, Kawashima S, Park MK.  Human type II GnRH receptor mediates effects of GnRH on cell proliferation  Zoolog Sci  2004  21(7):763-70  PubMed ID: 15277720
13800  Enomoto M, Seong JY, Kawashima S, Park MK.  Proliferation of TSU-Pr1, a human prostatic carcinoma cell line is stimulated by gonadotropin-releasing hormone  Life Sci . 2004 May 7;74(25):3141-52  2004  74(25):3141-52  PubMed ID: 15081579
2549  Nagai, Fusako, Hiyoshi, Yasuko, Sugimachi, Kumiko, Tamura, Hiro-Omi  Cytochrome P450 (CYP) expression in human myeloblastic and lymphoid cell lines.  Biol Pharm Bull  2002  25:383-5  PubMed ID: 11913539
2819  Uchida E, Mizuguchi H, Ishii-Watabe A, Hayakawa T.  Comparison of the efficiency and safety of non-viral vector-mediated gene transfer into a wide range of human cells.  Biol Pharm Bull  2002  25(7):891-7  PubMed ID: 12132664
13865  Jiang B, Hattori N, Liu B, Kitagawa K, Inagaki C.  Expression of swelling- and/or pH-regulated chloride channels (ClC-2, 3, 4 and 5) in human leukemic and normal immune cells  Life Sci  2002  70(12):1383-94  PubMed ID: 11883714
13869  Mizuguchi H, Hayakawa T.  Adenovirus vectors containing chimeric type 5 and type 35 fiber proteins exhibit altered and expanded tropism and increase the size limit of foreign genes  Gene  2002  285(1-2):69-77.  PubMed ID: 12039033
9032  N Kiyokawa, T Mori, T Taguchi, M Saito, K Mimori, T Suzuki, T Sekino, N Sato, H Nakajima, Y U Katagiri, T Takeda, J Fujimoto  Activation of the Caspase Cascade During Stx1-induced Apoptosis in Burkitt's Lymphoma Cells  J Cell Biochem  2001  81 (1), 128-42  PubMed ID: 11180403
13864  Fujino T, Tada T, Hosaka T, Beppu M, Kikugawa K.  Presence of oxidized protein hydrolase in human cell lines, rat tissues, and human/rat plasma  J Biochem  2000  127(2):307-13  PubMed ID: 10731698
11028  Y Tomita, T Kawasaki, V Bilim, M Takeda, K Takahashi  Tetrapeptide DEVD-aldehyde or YVAD-chloromethylketone inhibits Fas/Apo-1(CD95)-mediated apoptosis in renal-cell-cancer cells  Int J Cancer  1996  68(1):132-5  PubMed ID: 8895553
6246  Ohsawa K, Watanabe Y, Sato H.  Hantaan virus persistently infects marmoset B-lymphoblastoid cell line.  J Vet Med Sci  1995  57(5):931-4  PubMed ID: 8593305

トップへページトップへ
利用者成果(日)



戻る 戻る 理研トップページへ