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Cell No. : Cell Name
RCB0806 : Jurkat  update : 2024/04/11
CommentHuman T cell line, the same patient as JM. IL-2 productivity of this line was undetermined.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Todokoro, Kazuo
Year of deposit 1992
Animal _human < Mammals
Genus Homo
Species sapiens
Gender Male
Age at sampling 14 years
Tissue blood
Disease name acute T cell leukemia
Classification cancer
Memo_1 Mycoplasma was eliminated with MC-210.
Lifespan infinite
Morphology lymphocyte-like
Cellosaurus(Expasy) CVCL_0065
deposit info
lot info
Medium Medium List
Culture type Suspension cells
Culture medium RPMI1640 + 10% FBS
Culture method
Antibiotics Free
Passage method dilution
Culture information Passage ratio 1 : 10 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Virus (HIV) (-)
Virus (HTLV-1) (-)
Isozyme LD, NP
Chromosome mode Lot.1 : 42-92(50) : 42(2),43(1),44(6),45(21),46(14),47(5)/
STR(human) OK
deposit info
lot info
Relational File deposit infolot info
Reference information Reference 7
User's Publication 86

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1640  LaGree KA, Lee AT, Stetten G, Strauss PR.  The human Jurkat (FHCRC-11) cell line is heterogeneous in ploidy and cell size and releases detergent-soluble DNA.  Exp Hematol  1988  16(8):686-90  PubMed ID: 3165345  
4749  Wendler I1, Jentsch KD, Schneider J, Hunsmann G.  Efficient replication of HTLV-III and STLV-IIImac in human Jurkat cells.  Med Microbiol Immunol  1987  176(5):273-80  PubMed ID: 2443825   DOI: 10.1007/BF00190533
1685  Weiss A, Wiskocil RL, Stobo JD.  The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level.  J Immunol  1984  133(1):123-8  PubMed ID: 6327821  
1638  Pawelec G, Borowitz A, Krammer PH, Wernet P.  Constitutive interleukin 2 production by the JURKAT human leukemic T cell line.  Eur J Immunol  1982  12(5):387-92  PubMed ID: 6980126   DOI: 10.1002/eji.1830120506
1637  Kahle P, Wernet P, Rehbein A, Kumbier I, Pawelec G.  Cloning of functional human T lymphocytes by limiting dilution: impact of filler cells and interleukin 2 sources on cloning efficiencies.  Scand J Immunol  1981  14(5):493-502  PubMed ID: 6278580  
515  Gillis S, Watson J.  Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line.  J Exp Med  1980  152(6):1709-19  PubMed ID: 6778951   DOI: 10.1084/jem.152.6.1709
902  Schneider U, Schwenk HU, Bornkamm G.  Characterization of EBV-genome negative "null" and "T" cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma.  Int J Cancer  1977  19(5):621-6  PubMed ID: 68013   DOI: 10.1002/ijc.2910190505

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User's Publication
21598  Nishimura Y, Sato K, Koyanagi Y, Wakita T, Muramatsu M, Shimizu H, Bergelson JM, Arita M.  Enterovirus A71 does not meet the uncoating receptor SCARB2 at the cell surface.  PLoS Pathog  2024  20(2):e1012022  PubMed ID: 38359079   DOI: 10.1371/journal.ppat.1012022
19630  Bakalova R, Lazarova D, Sumiyoshi A, Shibata S, Zhelev Z, Nikolova B, Semkova S, Vlaykova T, Aoki I, Higashi T.  Redox-Cycling "Mitocans" as Effective New Developments in Anticancer Therapy  Int J Mol Sci  2023  24(9):8435  PubMed ID: 37176145   DOI: 10.3390/ijms24098435
21124  Suemura M, Shibutani S, Iwata H.  The endocytosis inhibitor dynasore induces a DNA damage response pathway that can be manipulated for enhanced apoptosis.  Biochem Biophys Res Commun  2023  645:1-9  PubMed ID: 36657293   DOI: 10.1016/j.bbrc.2023.01.035
17819  Shen M, Wang D, Sennari Y, Zeng Z, Baba R, Morimoto H, Kitamura N, Nakanishi T, Tsukada J, Ueno M, Todoroki Y, Iwata S, Yonezawa T, Tanaka Y, Osada Y, Yoshida Y.  Pentacyclic triterpenoid ursolic acid induces apoptosis with mitochondrial dysfunction in adult T-cell leukemia MT-4 cells to promote surrounding cell growth  Med Oncol  2022  39(8):118  PubMed ID: 35674939   DOI: 10.1007/s12032-022-01707-x
20498  Aoyama M, Tada M, Yokoo H, Demizu Y, Ishii-Watabe A.  Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates.  Pharm Res  2022    PubMed ID: 34961908   DOI: 10.1007/s11095-021-03158-x
16069  Nonaka Y, Ogawa T, Shoji H, Nishi N, Kamitori S, Nakamura T.  Crystal structure and conformational stability of a galectin-1 tandem-repeat mutant with a short linker  Glycobiology  2022  cwab101  PubMed ID: 34735570   DOI: 10.1093/glycob/cwab101
20787  Uchida K, Obayashi H, Minamihata K, Wakabayashi R, Goto M, Shimokawa N, Takagi M, Kamiya N.  Artificial Palmitoylation of Proteins Controls the Lipid Domain-Selective Anchoring on Biomembranes and the Raft-Dependent Cellular Internalization.  Langmuir  2022    PubMed ID: 35882009   DOI: 10.1021/acs.langmuir.2c01205
13052  Kawai S, Suzuki M, Arimoto S, Korenaga T, Yasukawa T.  Determination of membrane capacitance and cytoplasm conductivity by simultaneous electrorotation.  Analyst  2020    PubMed ID: 32462157   DOI: 10.1039/d0an00100g
13322  Bakalova R, Semkova S, Ivanova D, Zhelev Z, Miller T, Takeshima T, Shibata S, Lazarova D, Aoki I, Higashi T.  Selective Targeting of Cancerous Mitochondria and Suppression of Tumor Growth Using Redox-Active Treatment Adjuvant.  Oxid Med Cell Longev  2020    PubMed ID: 33204397   DOI: 10.1155/2020/6212935
10599  Yoshimi Utaka, Gengo Kashiwazaki, Sachiko Tajima, Yuko Fujiwara, Keitaro Sumi, Tomohiro Itoh, Takashi Kitayama  Antiproliferative effects of zerumbone-pendant derivatives on human T-cell lymphoid cell line Jurkat cells  Tetrahedron  2019  75:1343-1350    DOI: 10.1016/j.tet.2019.01.038
10946  Tsubasa Koga, Keiko Morotomi-Yano, Takashi Sakugawa, Hisato Saitoh, Ken-Ichi Yano  Nanosecond pulsed electric fields induce extracellular release of chromosomal DNA and histone citrullination in neutrophil-differentiated HL-60 cells  Sci Rep  2019  9(1):8451  PubMed ID: 31186478   DOI: 10.1038/s41598-019-44817-9
12485  Sharma N, Baek K, Shimokawa N, Takagi M.  Effect of temperature on raft-dependent endocytic cluster formation during activation of Jurkat T cells by concanavalin A  J Biosci Bioeng  2019  127(4):479-485  PubMed ID: 30355461   DOI: 10.1016/j.jbiosc.2018.09.014
14826  Nakashima M, Yamochi T, Watanabe M, Uchimaru K, Utsunomiya A, Higashihara M, Watanabe T, Horie R.  CD30 Characterizes Polylobated Lymphocytes and Disease Progression in HTLV-1-Infected Individuals  Clin Cancer Res  2018  24(21):5445-5457  PubMed ID: 30068708   DOI: 10.1158/1078-0432.CCR-18-0268
14450  Yabuuchi S, Endo S, Baek K, Hoshino K, Tsujino Y, Vestergaard MC, Takagi M.  Raft-dependent endocytic movement and intracellular cluster formation during T cell activation triggered by concanavalin A  J Biosci Bioeng  2017  124(6):685-693  PubMed ID: 28711300   DOI: 10.1016/j.jbiosc.2017.06.009
7069  Kataoka K, Shiraishi Y, Takeda Y, Sakata S, Matsumoto M, Nagano S, Maeda T, Nagata Y, Kitanaka A, Mizuno S, Tanaka H, Chiba K, Ito S, Watatani Y, Kakiuchi N, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Itonaga H, Imaizumi Y, Totoki Y, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Masuda K, Minato N, Kashiwase K, Izutsu K, Takaori-Kondo A, Miyazaki Y, Takahashi S, Shibata T, Kawamoto H, Akatsuka Y, Shimoda K, Takeuchi K, Seya T, Miyano S, Ogawa S.  Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.  Nature  2016  534:402-6  PubMed ID: 27281199   DOI: 10.1038/nature18294
7107  Yamazoe H, Ichikawa T, Hagihara Y, Iwasaki Y.  Generation of a patterned co-culture system composed of adherent cells and immobilized nonadherent cells.  Acta Biomater  2016  31:231-240  PubMed ID: 26685756   DOI: 10.1016/j.actbio.2015.12.016
9159  Tsukasa Nakanishi, Yuan Song, Cuiying He 1, Duo Wang, Kentaro Morita, Junichi Tsukada, Tamotsu Kanazawa, Yasuhiro Yoshida  Autophagy Is Associated With Cucurbitacin D-induced Apoptosis in Human T Cell Leukemia Cells  Med Oncol  2016  33 (4), 30  PubMed ID: 26913856   DOI: 10.1007/s12032-016-0743-y
12962  Hayashi K, Ouchi M, Endou H, Anzai N.  HOXB9 acts as a negative regulator of activated human T cells in response to amino acid deficiency  Immunol Cell Biol  2016  94(6):612-7.  PubMed ID: 26926958   DOI: 10.1038/icb.2016.13
14128  REGINA APPIAH-OPONG, ISAAC KWADWO ASANTE, DORCAS OSEI SAFO, ISAAC TUFFOUR, EBENEZER OFORI- ATTAH, TAKUHIRO UTO, ALEXANDER KWADWO NYARKO  Cytotoxic effects of Albizia zygia (DC) JF Macbr, a Ghanaian medicinal plant, against human T-lymphoblast-like leukemia, prostate and breast cancer cell lines  International Journal of Pharmacy and Pharmaceutical Sciences  2016  8   
7244  Ishii T, Sato K, Kakumoto T, Miura S, Touhara K, Takeuchi S, Nakata T.  Light generation of intracellular Ca(2+) signals by a genetically encoded protein BACCS.  Nat Commun  2015  6:8021  PubMed ID: 26282514   DOI: 10.1038/ncomms9021
7435  Ebina H, Kanemura Y, Misawa N, Sakuma T, Kobayashi T, Yamamoto T, Koyanagi Y.  A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector.  PLoS ONE  2015  10:e0120047  PubMed ID: 25781496   DOI: 10.1371/journal.pone.0120047
15173  Kataoka C, Suzuki T, Kotani O, Iwata-Yoshikawa N, Nagata N, Ami Y, Wakita T, Nishimura Y, Shimizu H.  The Role of VP1 Amino Acid Residue 145 of Enterovirus 71 in Viral Fitness and Pathogenesis in a Cynomolgus Monkey Model  PLoS Pathog  2015  11(7):e1005033  PubMed ID: 26181772   DOI: 10.1371/journal.ppat.1005033
14392  Tada M, Ishii-Watabe A, Suzuki T, Kawasaki N.  Development of a cell-based assay measuring the activation of FcγRIIa for the characterization of therapeutic monoclonal antibodies  PLoS One  2014  9(4):e95787  PubMed ID: 24752341   DOI: 10.1371/journal.pone.0095787
18093  Inoue T, Suzuki-Karasaki Y.  Mitochondrial superoxide mediates mitochondrial and endoplasmic reticulum dysfunctions in TRAIL-induced apoptosis in Jurkat cells  Free Radic Biol Med  2013  61:273-84  PubMed ID: 23608466   DOI: 10.1016/j.freeradbiomed.2013.04.020
7800  Tanaka Y, Matsumoto I, Iwanami K, Inoue A, Minami R, Umeda N, Kanamori A, Ochiai N, Miyazawa K, Sugihara M, Hayashi T, Goto D, Ito S, Sumida T.  Six-transmembrane epithelial antigen of prostate4 (STEAP4) is a tumor necrosis factor alpha-induced protein that regulates IL-6, IL-8, and cell proliferation in synovium from patients with rheumatoid arthritis.  Mod Rheumatol  2012  22:128-36  PubMed ID: 21633911   DOI: 10.1007/s10165-011-0475-y
14405  Qi H, Zhu B, Abe N, Shin Y, Murata Y, Nakamura Y.  Involvement of intracellular oxidative stress-sensitive pathway in phloxine B-induced photocytotoxicity in human T lymphocytic leukemia cells  Food Chem Toxicol  2012  50(6):1841-7  PubMed ID: 22440610   DOI: 10.1016/j.fct.2012.03.011
16593  Takahashi M, Elbarbary RA, Abe M, Sato M, Yoshida T, Yamada Y, Tamura M, Nashimoto M.  Elimination of specific miRNAs by naked 14-nt sgRNAs  PLoS One  2012  7(6):e38496  PubMed ID: 22675569   DOI: 10.1371/journal.pone.0038496
7821  Qi H, Takano H, Kato Y, Wu Q, Ogata C, Zhu B, Murata Y, Nakamura Y.  Hydrogen [corrected] peroxide-dependent photocytotoxicity by phloxine B, a xanthene-type food colorant.  Biochim. Biophys. Acta  2011  1810:704-12  PubMed ID: 21565256   DOI: 10.1016/j.bbagen.2011.04.010
7874  Wang F, Fang W, Zhang MR, Zhao M, Liu B, Wang Z, Hua Z, Yang M, Kumata K, Hatori A, Yamasaki T, Yanamoto K, Suzuki K.  Evaluation of chemotherapy response in VX2 rabbit lung cancer with 18F-labeled C2A domain of synaptotagmin I.  J. Nucl. Med.  2011  52:592-9  PubMed ID: 21421722   DOI: 10.2967/jnumed.110.081588
6237  Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S.  HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7.  Atherosclerosis   2011  217(2):407-14  PubMed ID: 21762915   DOI: 10.1016/j.atherosclerosis.2011.06.031
14408  Ding N, Yamashita U, Matsuoka H, Sugiura T, Tsukada J, Noguchi J, Yoshida Y.  Apoptosis induction through proteasome inhibitory activity of cucurbitacin D in human T-cell leukemia  Cancer  2011  117(12):2735-46  PubMed ID: 21656752   DOI: 10.1002/cncr.25711
18256  Hashidate T, Murakami N, Nakagawa M, Ichikawa M, Kurokawa M, Shimizu T, Nakamura M.  AML1 enhances the expression of leukotriene B4 type-1 receptor in leukocytes  FASEB J  2010  24(9):3500-10  PubMed ID: 20395453   DOI: 10.1096/fj.10-156844
8582  Zhang G, Wu H, Zhu B, Shimoishi Y, Nakamura Y, Murata Y.  Induction of apoptosis by beta-carotene and dimethyl tetrasulfide assisted by UVA irradiation in HL-60 cells.  Biosci. Biotechnol. Biochem.  2009  73:1014-20  PubMed ID: 19420723   DOI: 10.1271/bbb.80794
8667  Kobayashi K, Yasuda Y, Shintani Y, Sumitomo T, Saga T, Kimura M, Yamamoto A, Mori T, Maeda A, Yamaguchi Y, Morita A.  The development of a filter to enhance the efficacy and safety of excimer light (308 nm) therapy.  Photodermatol Photoimmunol Photomed  2009  25:30-6  PubMed ID: 19152513   DOI: 10.1111/j.1600-0781.2009.00396.x
9078  Yorihiro Nishimura, Masayuki Shimojima, Yoshio Tano, Tatsuo Miyamura, Takaji Wakita, Hiroyuki Shimizu  Human P-selectin Glycoprotein ligand-1 Is a Functional Receptor for Enterovirus 71  Nat Med  2009  15 (7), 794-7  PubMed ID: 19543284   DOI: 10.1038/nm.1961
14412  Takeshita A, Shinjo K, Yamakage N, Ono T, Hirano I, Matsui H, Shigeno K, Nakamura S, Tobita T, Maekawa M, Ohnishi K, Sugimoto Y, Kiyoi H, Naoe T, Ohno R.  CMC-544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma  Br J Haematol  2009  146(1):34-43  PubMed ID: 19388933   DOI: 10.1111/j.1365-2141.2009.07701.x
16556  Nakase I, Hirose H, Tanaka G, Tadokoro A, Kobayashi S, Takeuchi T, Futaki S.  Cell-surface accumulation of flock house virus-derived peptide leads to efficient internalization via macropinocytosis  Mol Ther  2009  17(11):1868-76  PubMed ID: 19707187   DOI: 10.1038/mt.2009.192
18335  Matsumoto K, Murao K, Imachi H, Nishiuchi T, Cao W, Yu X, Li J, Ahmed RA, Iwama H, Kobayashi R, Tokumitsu H, Ishida T.  The role of calcium/calmodulin-dependent protein kinase cascade on MIP-1alpha gene expression of ATL cells  Exp Hematol  2008  36(4):390-400  PubMed ID: 18249060   DOI: 10.1016/j.exphem.2007.11.013
8761  Okamura A, Hagiwara T, Yamagami S, Yamaguchi M, Shinbo T, Kanamori T, Kondo S, Miwa K, Itagaki I.  Effective cell separation utilizing poly(N-isopropylacrylamide)-grafted polypropylene membrane containing adsorbed antibody.  J. Biosci. Bioeng.  2008  105:221-5  PubMed ID: 18397772   DOI: 10.1263/jbb.105.221
12791  Fukuzawa M, Yamaguchi R, Hide I, Chen Z, Hirai Y, Sugimoto A, Yasuhara T, Nakata Y.  Possible involvement of long chain fatty acids in the spores of Ganoderma lucidum (Reishi Houshi) to its anti-tumor activity  Biol Pharm Bull  2008  31(10):1933-7  PubMed ID: 18827358   DOI: 10.1248/bpb.31.1933
18614  Shimada S, Nakamura M, Tanaka Y, Tsutsumi K, Katano M, Masuko K, Yudoh K, Koizuka I, Kato T.  Crosslinking of the CD69 molecule enhances S100A9 production in activated neutrophils  Microbiol Immunol  2007  51(1):87-98  PubMed ID: 17237603   DOI: 10.1111/j.1348-0421.2007.tb03878.x
9059  Y-C Jung, E Mizuki, T Akao, J-C Côté  Isolation and Characterization of a Novel Bacillus Thuringiensis Strain Expressing a Novel Crystal Protein With Cytocidal Activity Against Human Cancer Cells  J Appl Microbiol  2007  103 (1), 65-79  PubMed ID: 17584453   DOI: 10.1111/j.1365-2672.2006.03260.x
15599  Kato N, Tanaka J, Sugita J, Toubai T, Miura Y, Ibata M, Syono Y, Ota S, Kondo T, Asaka M, Imamura M.  Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells  Leukemia  2007  21(10):2103-8  PubMed ID: 17625602   DOI: 10.1038/sj.leu.2404862
16559  Nishida M, Usuda S, Okabe M, Miyakoda H, Komatsu M, Hanaoka H, Teshigawara K, Niwa O.  Characterization of novel murine anti-CD20 monoclonal antibodies and their comparison to 2B8 and c2B8 (rituximab)  Int J Oncol  2007  31(1):29-40  PubMed ID: 17549402  
15553  Masatoshi Beppu, Yoshie Nakadai, Yu Igarashi  Apoptosis Inducing and Enhancing Activities of Environmental Estrogenic Compounds  Journal of Health Science  2006  52:831-837    DOI: 10.1248/jhs.52.831
16902  Fujita K, Tsujimura A, Miyagawa Y, Kiuchi H, Matsuoka Y, Takao T, Takada S, Nonomura N, Okuyama A.  Isolation of germ cells from leukemia and lymphoma cells in a human in vitro model: potential clinical application for restoring human fertility after anticancer therapy  Cancer Res  2006  66(23):11166-71  PubMed ID: 17145860   DOI: 10.1158/0008-5472.CAN-06-2326
3413  Yamashita, Satoko, Katayama, Hideki, Saitoh, Hiroyuki, Akao, Tetsuyuki, Park, Yu Shin, Mizuki, Eiichi, Ohba, Michio, Ito, Akio  Typical Three-Domain Cry Proteins of Bacillus thuringiensis Strain A1462 Exhibit Cytocidal Activity on Limited Human Cancer Cells.  J Biochem  2005  138:663-72  PubMed ID: 16428294   DOI: 10.1093/jb/mvi177
2892  Katayama H, Yokota H, Akao T, Nakamura O, Ohba M, Mekada E, Mizuki E  Parasporin-1, a novel cytotoxic protein to human cells from non-insecticidal parasporal inclusions of Bacillus thuringiensis  J Biochem (Tokyo)  2005  137:17-25  PubMed ID: 15713879   DOI: 10.1093/jb/mvi003
2974  Tamura H, Dan K, Tamada K, Nakamura K, Shioi Y, Hyodo H, Wang SD, Dong H, Chen L, Ogata K  Expression of functional B7-H2 and B7.2 costimulatory molecules and their prognostic implications in de novo acute myeloid leukemia  Clin Cancer Res  2005  15:5708-5717  PubMed ID: 16115907   DOI: 10.1158/1078-0432.CCR-04-2672
2958  Awata T, Kurihara S, Takata N, Neda T, Iizuka H, Ohkubo T, Osaki M, Watanabe M, Nakashima Y, Inukai K, Inoue I, Kawasaki I, Mori K, Yoneya S, Katayama S  Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes.  Biochem Biophys Res Commun  2005  333:679-85  PubMed ID: 15963467   DOI: 10.1016/j.bbrc.2005.05.167
2875  Miyoshi N, Naniwa K, Kumagai T, Uchida K, Osawa T, Nakamura Y.  Alpha-tocopherol-mediated caspase-3 up-regulation enhances susceptibility to apoptotic stimuli.  Biochem Biophys Res Commun  2005  334(2):466-73  PubMed ID: 16009347   DOI: 10.1016/j.bbrc.2005.06.113
2891  Kishimoto S, Muramatsu M, Gokoh M, Oka S, Waku K, Sugiura T.  Endogenous cannabinoid receptor ligand induces the migration of human natural killer cells.  J Biochem  2005  137(2):217-23  PubMed ID: 15749836   DOI: 10.1093/jb/mvi021
2896  Yamanaka M, Eda S, Beppu M.  Carbohydrate chains and phosphatidylserine successively work as signals for apoptotic cell removal.  Biochem Biophys Res Commun  2005  328(1):273-80  PubMed ID: 15670780   DOI: 10.1016/j.bbrc.2004.12.171
3349  Hirano K, Miki Y, Hirai Y, Sato R, Itoh T, Hayashi A, Yamanaka M, Eda S, Beppu M.  A multifunctional shuttling protein nucleolin is a macrophage receptor for apoptotic cells.  J Biol Chem  2005  280(47):39284-93  PubMed ID: 16135517   DOI: 10.1074/jbc.M505275200
3387  Ogawa Y, Morikawa N, Ohkubo-Suzuki A, Miyoshi S, Arakawa H, Kita Y, Nishimura S.  An epoch-making application of discharge plasma phenomenon to gene-transfer.  Biotechnol Bioeng  2005  92(7):865-70  PubMed ID: 16170826   DOI: 10.1002/bit.20659
9048  Shiro Okumura, Hiroyuki Saitoh, Tomoyuki Ishikawa, Naoya Wasano, Satoko Yamashita, Ken-Ichi Kusumoto, Tetsuyuki Akao, Eiichi Mizuki, Michio Ohba, Kuniyo Inouye  Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines  J Agric Food Chem  2005  53 (16), 6313-8  PubMed ID: 16076112   DOI: 10.1021/jf0506129
4437  Hamasu T, Inanami O, Tsujitani M, Yokoyama K, Takahashi E, Kashiwakura I, Kuwabara M.  Post-irradiation hypoxic incubation of X-irradiated MOLT-4 cells reduces apoptotic cell death by changing the intracellular redox state and modulating SAPK/JNK pathways  Apoptosis  2005  10(3):557-67  PubMed ID: 15909118   DOI: 10.1007/s10495-005-1888-x
16557  Matsura T, Togawa A, Kai M, Nishida T, Nakada J, Ishibe Y, Kojo S, Yamamoto Y, Yamada K.  The presence of oxidized phosphatidylserine on Fas-mediated apoptotic cell surface  Biochim Biophys Acta  2005  1736(3):181-8  PubMed ID: 16168707   DOI: 10.1016/j.bbalip.2005.08.011
16606  Hattori N, Ikekubo K, Nakaya Y, Kitagawa K, Inagaki C.  Immunoglobulin G subclasses and prolactin (PRL) isoforms in macroprolactinemia due to anti-PRL autoantibodies  J Clin Endocrinol Metab  2005  90(5):3036-44  PubMed ID: 15687336   DOI: 10.1210/jc.2004-1600
2823  Yamauchi, Ritsuko, Morita, Akimichi, Yasuda, Yoko, Grether-Beck, Susanne, Klotz, Lars-Oliver, Tsuji, Takuo, Krutmann, Jean  Different susceptibility of malignant versus nonmalignant human T cells toward ultraviolet A-1 radiation-induced apoptosis.  J Invest Dermatol  2004  122:477-83  PubMed ID: 15009733   DOI: 10.1046/j.0022-202X.2003.22106.x
2894  Ito, Akio, Sasaguri, Yasuyuki, Kitada, Sakae, Kusaka, Yoshitomo, Kuwano, Kyoko, Masutomi, Kenjiro, Mizuki, Eiichi, Akao, Tetsuyuki, Ohba, Michio  A Bacillus thuringiensis crystal protein with selective cytocidal action to human cells.  J Biol Chem  2004  279:21282-6  PubMed ID: 15026424   DOI: 10.1074/jbc.M401881200
3403  Ozaki, Kouichi, Inoue, Katsumi, Sato, Hiroshi, Iida, Aritoshi, Ohnishi, Yozo, Sekine, Akihiro, Sato, Hideyuki, Odashiro, Keita, Nobuyoshi, Masakiyo, Hori, Masatsugu, Nakamura, Yusuke, Tanaka, Toshihiro  Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.  Nature  2004  429:72-5  PubMed ID: 15129282   DOI: 10.1038/nature02502
3340  Watanabe, Dai, Ezoe, Sachiko, Fujimoto, Minoru, Kimura, Akihiro, Saito, Yoshiyuki, Nagai, Hisaki, Tachibana, Isao, Matsumura, Itaru, Tanaka, Toshio, Kanegane, Hirokazu, Miyawaki, Toshio, Emi, Mitsuru, Kanakura, Yuzuru, Kawase, Ichiro, Naka, Tetsuji, Kishimoto, Tadamitsu  Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines.  Br J Haematol  2004  126:726-35  PubMed ID: 15327527   DOI: 10.1111/j.1365-2141.2004.05107.x
18468  Suppression of T cell responses by chondromodulin I, a cartilage-derived angiogenesis inhibitory factor: therapeutic potential in rheumatoid arthritis  Suppression of T cell responses by chondromodulin I, a cartilage-derived angiogenesis inhibitory factor: therapeutic potential in rheumatoid arthritis  Arthritis Rheum  2004  50(3):828-39  PubMed ID: 15022325   DOI: 10.1002/art.20193
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