Cell No. : Cell Name RCB0806 : Jurkat  update : 2022/11/29
Comment			Human T cell line, the same patient as JM. IL-2 productivity of this line was undetermined.
Comment from the depositor
Terms and conditions			There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form			Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)
			Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
	Basic information	Depositor	Todokoro, Kazuo
		Year of deposit	1992
		Animal	human < Mammals
		Genus	Homo
		Species	sapiens
		Gender	Male
		Age at sampling	14 years
		Tissue	blood
		Disease name	acute T cell leukemia
		Classification	cancer
		Memo_1	Mycoplasma was eliminated with MC-210.
		Lifespan	infinite
		Morphology	lymphocyte-like
		Cellosaurus(Expasy)	CVCL_0065
			deposit info	lot info
		Medium	Medium List
		Culture type		Suspension cells
		Medium and additives		RPMI1640 + 10% FBS
		Antibiotics		Free
		Passage method		dilution
	Culture information	Passage ratio		1 : 10 split
		SC frequency		Subculture : 2 times/week
		Temperature		37 ℃
		Freeze medium		Medium + 10% DMSO
		Freezing method		Slow freezing
		Mycoplasma		(-)
		Virus (HIV)		(-)
		Virus (HTLV-1)		(-)
		Isozyme		LD, NP
		Chromosome mode		Lot.1 : 42-92(50) : 42(2),43(1),44(6),45(21),46(14),47(5)/
		STR(human)		OK
Images			deposit info	lot info
Relational File			deposit info	lot info
				Jurkat_CD3.pdf
Reference information		Reference	7
		User's Publication	74

Top

Reference

1640  LaGree KA, Lee AT, Stetten G, Strauss PR.  The human Jurkat (FHCRC-11) cell line is heterogeneous in ploidy and cell size and releases detergent-soluble DNA.  Exp Hematol  1988  16(8):686-90  PubMed ID: 3165345

4749  Wendler I1, Jentsch KD, Schneider J, Hunsmann G.  Efficient replication of HTLV-III and STLV-IIImac in human Jurkat cells.  Med Microbiol Immunol  1987  176(5):273-80  PubMed ID: 2443825

1685  Weiss A, Wiskocil RL, Stobo JD.  The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level.  J Immunol  1984  133(1):123-8  PubMed ID: 6327821

1638  Pawelec G, Borowitz A, Krammer PH, Wernet P.  Constitutive interleukin 2 production by the JURKAT human leukemic T cell line.  Eur J Immunol  1982  12(5):387-92  PubMed ID: 6980126   DOI: 10.1002/eji.1830120506

1637  Kahle P, Wernet P, Rehbein A, Kumbier I, Pawelec G.  Cloning of functional human T lymphocytes by limiting dilution: impact of filler cells and interleukin 2 sources on cloning efficiencies.  Scand J Immunol  1981  14(5):493-502  PubMed ID: 6278580

515  Gillis S, Watson J.  Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line.  J Exp Med  1980  152(6):1709-19  PubMed ID: 6778951   DOI: 10.1084/jem.152.6.1709

902  Schneider U, Schwenk HU, Bornkamm G.  Characterization of EBV-genome negative "null" and "T" cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma.  Int J Cancer  1977  19(5):621-6  PubMed ID: 68013   DOI: 10.1002/ijc.2910190505

Top

User's Publication

20498  Aoyama M, Tada M, Yokoo H, Demizu Y, Ishii-Watabe A.  Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates.  Pharm Res  2022    PubMed ID: 34961908   DOI: 10.1007/s11095-021-03158-x

16069  Nonaka Y, Ogawa T, Shoji H, Nishi N, Kamitori S, Nakamura T.  Crystal structure and conformational stability of a galectin-1 tandem-repeat mutant with a short linker  Glycobiology  2022  cwab101  PubMed ID: 34735570   DOI: 10.1093/glycob/cwab101

20787  Uchida K, Obayashi H, Minamihata K, Wakabayashi R, Goto M, Shimokawa N, Takagi M, Kamiya N.  Artificial Palmitoylation of Proteins Controls the Lipid Domain-Selective Anchoring on Biomembranes and the Raft-Dependent Cellular Internalization.  Langmuir  2022    PubMed ID: 35882009   DOI: 10.1021/acs.langmuir.2c01205

13052  Kawai S, Suzuki M, Arimoto S, Korenaga T, Yasukawa T.  Determination of membrane capacitance and cytoplasm conductivity by simultaneous electrorotation.  Analyst  2020    PubMed ID: 32462157   DOI: 10.1039/d0an00100g

13322  Bakalova R, Semkova S, Ivanova D, Zhelev Z, Miller T, Takeshima T, Shibata S, Lazarova D, Aoki I, Higashi T.  Selective Targeting of Cancerous Mitochondria and Suppression of Tumor Growth Using Redox-Active Treatment Adjuvant.  Oxid Med Cell Longev  2020    PubMed ID: 33204397   DOI: 10.1155/2020/6212935

10599  Yoshimi Utaka, Gengo Kashiwazaki, Sachiko Tajima, Yuko Fujiwara, Keitaro Sumi, Tomohiro Itoh, Takashi Kitayama  Antiproliferative effects of zerumbone-pendant derivatives on human T-cell lymphoid cell line Jurkat cells  Tetrahedron  2019  75:1343-1350    DOI: 10.1016/j.tet.2019.01.038

10946  Tsubasa Koga, Keiko Morotomi-Yano, Takashi Sakugawa, Hisato Saitoh, Ken-Ichi Yano  Nanosecond pulsed electric fields induce extracellular release of chromosomal DNA and histone citrullination in neutrophil-differentiated HL-60 cells  Sci Rep  2019  9(1):8451  PubMed ID: 31186478   DOI: 10.1038/s41598-019-44817-9

12485  Sharma N, Baek K, Shimokawa N, Takagi M.  Effect of temperature on raft-dependent endocytic cluster formation during activation of Jurkat T cells by concanavalin A  J Biosci Bioeng  2019  127(4):479-485  PubMed ID: 30355461   DOI: 10.1016/j.jbiosc.2018.09.014

14826  Nakashima M, Yamochi T, Watanabe M, Uchimaru K, Utsunomiya A, Higashihara M, Watanabe T, Horie R.  CD30 Characterizes Polylobated Lymphocytes and Disease Progression in HTLV-1-Infected Individuals  Clin Cancer Res  2018  24(21):5445-5457  PubMed ID: 30068708   DOI: 10.1158/1078-0432.CCR-18-0268

14450  Yabuuchi S, Endo S, Baek K, Hoshino K, Tsujino Y, Vestergaard MC, Takagi M.  Raft-dependent endocytic movement and intracellular cluster formation during T cell activation triggered by concanavalin A  J Biosci Bioeng  2017  124(6):685-693  PubMed ID: 28711300   DOI: 10.1016/j.jbiosc.2017.06.009

7069  Kataoka K, Shiraishi Y, Takeda Y, Sakata S, Matsumoto M, Nagano S, Maeda T, Nagata Y, Kitanaka A, Mizuno S, Tanaka H, Chiba K, Ito S, Watatani Y, Kakiuchi N, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Itonaga H, Imaizumi Y, Totoki Y, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Masuda K, Minato N, Kashiwase K, Izutsu K, Takaori-Kondo A, Miyazaki Y, Takahashi S, Shibata T, Kawamoto H, Akatsuka Y, Shimoda K, Takeuchi K, Seya T, Miyano S, Ogawa S.  Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.  Nature  2016  534:402-6  PubMed ID: 27281199   DOI: 10.1038/nature18294

7107  Yamazoe H, Ichikawa T, Hagihara Y, Iwasaki Y.  Generation of a patterned co-culture system composed of adherent cells and immobilized nonadherent cells.  Acta Biomater  2016  31:231-240  PubMed ID: 26685756   DOI: 10.1016/j.actbio.2015.12.016

9159  Tsukasa Nakanishi, Yuan Song, Cuiying He 1, Duo Wang, Kentaro Morita, Junichi Tsukada, Tamotsu Kanazawa, Yasuhiro Yoshida  Autophagy Is Associated With Cucurbitacin D-induced Apoptosis in Human T Cell Leukemia Cells  Med Oncol  2016  33 (4), 30  PubMed ID: 26913856   DOI: 10.1007/s12032-016-0743-y

12962  Hayashi K, Ouchi M, Endou H, Anzai N.  HOXB9 acts as a negative regulator of activated human T cells in response to amino acid deficiency  Immunol Cell Biol  2016  94(6):612-7.  PubMed ID: 26926958   DOI: 10.1038/icb.2016.13

14128  REGINA APPIAH-OPONG, ISAAC KWADWO ASANTE, DORCAS OSEI SAFO, ISAAC TUFFOUR, EBENEZER OFORI- ATTAH, TAKUHIRO UTO, ALEXANDER KWADWO NYARKO  Cytotoxic effects of Albizia zygia (DC) JF Macbr, a Ghanaian medicinal plant, against human T-lymphoblast-like leukemia, prostate and breast cancer cell lines  International Journal of Pharmacy and Pharmaceutical Sciences  2016  8

7244  Ishii T, Sato K, Kakumoto T, Miura S, Touhara K, Takeuchi S, Nakata T.  Light generation of intracellular Ca(2+) signals by a genetically encoded protein BACCS.  Nat Commun  2015  6:8021  PubMed ID: 26282514   DOI: 10.1038/ncomms9021

7435  Ebina H, Kanemura Y, Misawa N, Sakuma T, Kobayashi T, Yamamoto T, Koyanagi Y.  A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector.  PLoS ONE  2015  10:e0120047  PubMed ID: 25781496   DOI: 10.1371/journal.pone.0120047

15173  Kataoka C, Suzuki T, Kotani O, Iwata-Yoshikawa N, Nagata N, Ami Y, Wakita T, Nishimura Y, Shimizu H.  The Role of VP1 Amino Acid Residue 145 of Enterovirus 71 in Viral Fitness and Pathogenesis in a Cynomolgus Monkey Model  PLoS Pathog  2015  11(7):e1005033  PubMed ID: 26181772   DOI: 10.1371/journal.ppat.1005033

14392  Tada M, Ishii-Watabe A, Suzuki T, Kawasaki N.  Development of a cell-based assay measuring the activation of FcγRIIa for the characterization of therapeutic monoclonal antibodies  PLoS One  2014  9(4):e95787  PubMed ID: 24752341   DOI: 10.1371/journal.pone.0095787

7800  Tanaka Y, Matsumoto I, Iwanami K, Inoue A, Minami R, Umeda N, Kanamori A, Ochiai N, Miyazawa K, Sugihara M, Hayashi T, Goto D, Ito S, Sumida T.  Six-transmembrane epithelial antigen of prostate4 (STEAP4) is a tumor necrosis factor alpha-induced protein that regulates IL-6, IL-8, and cell proliferation in synovium from patients with rheumatoid arthritis.  Mod Rheumatol  2012  22:128-36  PubMed ID: 21633911   DOI: 10.1007/s10165-011-0475-y

14405  Qi H, Zhu B, Abe N, Shin Y, Murata Y, Nakamura Y.  Involvement of intracellular oxidative stress-sensitive pathway in phloxine B-induced photocytotoxicity in human T lymphocytic leukemia cells  Food Chem Toxicol  2012  50(6):1841-7  PubMed ID: 22440610   DOI: 10.1016/j.fct.2012.03.011

16593  Takahashi M, Elbarbary RA, Abe M, Sato M, Yoshida T, Yamada Y, Tamura M, Nashimoto M.  Elimination of specific miRNAs by naked 14-nt sgRNAs  PLoS One  2012  7(6):e38496  PubMed ID: 22675569   DOI: 10.1371/journal.pone.0038496

7821  Qi H, Takano H, Kato Y, Wu Q, Ogata C, Zhu B, Murata Y, Nakamura Y.  Hydrogen [corrected] peroxide-dependent photocytotoxicity by phloxine B, a xanthene-type food colorant.  Biochim. Biophys. Acta  2011  1810:704-12  PubMed ID: 21565256   DOI: 10.1016/j.bbagen.2011.04.010

7874  Wang F, Fang W, Zhang MR, Zhao M, Liu B, Wang Z, Hua Z, Yang M, Kumata K, Hatori A, Yamasaki T, Yanamoto K, Suzuki K.  Evaluation of chemotherapy response in VX2 rabbit lung cancer with 18F-labeled C2A domain of synaptotagmin I.  J. Nucl. Med.  2011  52:592-9  PubMed ID: 21421722   DOI: 10.2967/jnumed.110.081588

6237  Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S.  HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7.  Atherosclerosis   2011  217(2):407-14  PubMed ID: 21762915   DOI: 10.1016/j.atherosclerosis.2011.06.031

14408  Ding N, Yamashita U, Matsuoka H, Sugiura T, Tsukada J, Noguchi J, Yoshida Y.  Apoptosis induction through proteasome inhibitory activity of cucurbitacin D in human T-cell leukemia  Cancer  2011  117(12):2735-46  PubMed ID: 21656752   DOI: 10.1002/cncr.25711

8582  Zhang G, Wu H, Zhu B, Shimoishi Y, Nakamura Y, Murata Y.  Induction of apoptosis by beta-carotene and dimethyl tetrasulfide assisted by UVA irradiation in HL-60 cells.  Biosci. Biotechnol. Biochem.  2009  73:1014-20  PubMed ID: 19420723   DOI: 10.1271/bbb.80794

8667  Kobayashi K, Yasuda Y, Shintani Y, Sumitomo T, Saga T, Kimura M, Yamamoto A, Mori T, Maeda A, Yamaguchi Y, Morita A.  The development of a filter to enhance the efficacy and safety of excimer light (308 nm) therapy.  Photodermatol Photoimmunol Photomed  2009  25:30-6  PubMed ID: 19152513   DOI: 10.1111/j.1600-0781.2009.00396.x

9078  Yorihiro Nishimura, Masayuki Shimojima, Yoshio Tano, Tatsuo Miyamura, Takaji Wakita, Hiroyuki Shimizu  Human P-selectin Glycoprotein ligand-1 Is a Functional Receptor for Enterovirus 71  Nat Med  2009  15 (7), 794-7  PubMed ID: 19543284   DOI: 10.1038/nm.1961

14412  Takeshita A, Shinjo K, Yamakage N, Ono T, Hirano I, Matsui H, Shigeno K, Nakamura S, Tobita T, Maekawa M, Ohnishi K, Sugimoto Y, Kiyoi H, Naoe T, Ohno R.  CMC-544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma  Br J Haematol  2009  146(1):34-43  PubMed ID: 19388933   DOI: 10.1111/j.1365-2141.2009.07701.x

16556  Nakase I, Hirose H, Tanaka G, Tadokoro A, Kobayashi S, Takeuchi T, Futaki S.  Cell-surface accumulation of flock house virus-derived peptide leads to efficient internalization via macropinocytosis  Mol Ther  2009  17(11):1868-76  PubMed ID: 19707187   DOI: 10.1038/mt.2009.192

8761  Okamura A, Hagiwara T, Yamagami S, Yamaguchi M, Shinbo T, Kanamori T, Kondo S, Miwa K, Itagaki I.  Effective cell separation utilizing poly(N-isopropylacrylamide)-grafted polypropylene membrane containing adsorbed antibody.  J. Biosci. Bioeng.  2008  105:221-5  PubMed ID: 18397772   DOI: 10.1263/jbb.105.221

12791  Fukuzawa M, Yamaguchi R, Hide I, Chen Z, Hirai Y, Sugimoto A, Yasuhara T, Nakata Y.  Possible involvement of long chain fatty acids in the spores of Ganoderma lucidum (Reishi Houshi) to its anti-tumor activity  Biol Pharm Bull  2008  31(10):1933-7  PubMed ID: 18827358   DOI: 10.1248/bpb.31.1933

9059  Y-C Jung, E Mizuki, T Akao, J-C Côté  Isolation and Characterization of a Novel Bacillus Thuringiensis Strain Expressing a Novel Crystal Protein With Cytocidal Activity Against Human Cancer Cells  J Appl Microbiol  2007  103 (1), 65-79  PubMed ID: 17584453   DOI: 10.1111/j.1365-2672.2006.03260.x

15599  Kato N, Tanaka J, Sugita J, Toubai T, Miura Y, Ibata M, Syono Y, Ota S, Kondo T, Asaka M, Imamura M.  Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells  Leukemia  2007  21(10):2103-8  PubMed ID: 17625602   DOI: 10.1038/sj.leu.2404862

16559  Nishida M, Usuda S, Okabe M, Miyakoda H, Komatsu M, Hanaoka H, Teshigawara K, Niwa O.  Characterization of novel murine anti-CD20 monoclonal antibodies and their comparison to 2B8 and c2B8 (rituximab)  Int J Oncol  2007  31(1):29-40  PubMed ID: 17549402

15553  Masatoshi Beppu, Yoshie Nakadai, Yu Igarashi  Apoptosis Inducing and Enhancing Activities of Environmental Estrogenic Compounds  Journal of Health Science  2006  52:831-837    DOI: 10.1248/jhs.52.831

16902  Fujita K, Tsujimura A, Miyagawa Y, Kiuchi H, Matsuoka Y, Takao T, Takada S, Nonomura N, Okuyama A.  Isolation of germ cells from leukemia and lymphoma cells in a human in vitro model: potential clinical application for restoring human fertility after anticancer therapy  Cancer Res  2006  66(23):11166-71  PubMed ID: 17145860   DOI: 10.1158/0008-5472.CAN-06-2326

3413  Yamashita, Satoko, Katayama, Hideki, Saitoh, Hiroyuki, Akao, Tetsuyuki, Park, Yu Shin, Mizuki, Eiichi, Ohba, Michio, Ito, Akio  Typical Three-Domain Cry Proteins of Bacillus thuringiensis Strain A1462 Exhibit Cytocidal Activity on Limited Human Cancer Cells.  J Biochem  2005  138:663-72  PubMed ID: 16428294   DOI: 10.1093/jb/mvi177

2892  Katayama H, Yokota H, Akao T, Nakamura O, Ohba M, Mekada E, Mizuki E  Parasporin-1, a novel cytotoxic protein to human cells from non-insecticidal parasporal inclusions of Bacillus thuringiensis  J Biochem (Tokyo)  2005  137:17-25  PubMed ID: 15713879   DOI: 10.1093/jb/mvi003

2974  Tamura H, Dan K, Tamada K, Nakamura K, Shioi Y, Hyodo H, Wang SD, Dong H, Chen L, Ogata K  Expression of functional B7-H2 and B7.2 costimulatory molecules and their prognostic implications in de novo acute myeloid leukemia  Clin Cancer Res  2005  15:5708-5717  PubMed ID: 16115907   DOI: 10.1158/1078-0432.CCR-04-2672

2958  Awata T, Kurihara S, Takata N, Neda T, Iizuka H, Ohkubo T, Osaki M, Watanabe M, Nakashima Y, Inukai K, Inoue I, Kawasaki I, Mori K, Yoneya S, Katayama S  Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes.  Biochem Biophys Res Commun  2005  333:679-85  PubMed ID: 15963467   DOI: 10.1016/j.bbrc.2005.05.167

2875  Miyoshi N, Naniwa K, Kumagai T, Uchida K, Osawa T, Nakamura Y.  Alpha-tocopherol-mediated caspase-3 up-regulation enhances susceptibility to apoptotic stimuli.  Biochem Biophys Res Commun  2005  334(2):466-73  PubMed ID: 16009347   DOI: 10.1016/j.bbrc.2005.06.113

2891  Kishimoto S, Muramatsu M, Gokoh M, Oka S, Waku K, Sugiura T.  Endogenous cannabinoid receptor ligand induces the migration of human natural killer cells.  J Biochem  2005  137(2):217-23  PubMed ID: 15749836   DOI: 10.1093/jb/mvi021

2896  Yamanaka M, Eda S, Beppu M.  Carbohydrate chains and phosphatidylserine successively work as signals for apoptotic cell removal.  Biochem Biophys Res Commun  2005  328(1):273-80  PubMed ID: 15670780   DOI: 10.1016/j.bbrc.2004.12.171

3349  Hirano K, Miki Y, Hirai Y, Sato R, Itoh T, Hayashi A, Yamanaka M, Eda S, Beppu M.  A multifunctional shuttling protein nucleolin is a macrophage receptor for apoptotic cells.  J Biol Chem  2005  280(47):39284-93  PubMed ID: 16135517   DOI: 10.1074/jbc.M505275200

3387  Ogawa Y, Morikawa N, Ohkubo-Suzuki A, Miyoshi S, Arakawa H, Kita Y, Nishimura S.  An epoch-making application of discharge plasma phenomenon to gene-transfer.  Biotechnol Bioeng  2005  92(7):865-70  PubMed ID: 16170826   DOI: 10.1002/bit.20659

9048  Shiro Okumura, Hiroyuki Saitoh, Tomoyuki Ishikawa, Naoya Wasano, Satoko Yamashita, Ken-Ichi Kusumoto, Tetsuyuki Akao, Eiichi Mizuki, Michio Ohba, Kuniyo Inouye  Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines  J Agric Food Chem  2005  53 (16), 6313-8  PubMed ID: 16076112   DOI: 10.1021/jf0506129

4437  Hamasu T, Inanami O, Tsujitani M, Yokoyama K, Takahashi E, Kashiwakura I, Kuwabara M.  Post-irradiation hypoxic incubation of X-irradiated MOLT-4 cells reduces apoptotic cell death by changing the intracellular redox state and modulating SAPK/JNK pathways  Apoptosis  2005  10(3):557-67  PubMed ID: 15909118   DOI: 10.1007/s10495-005-1888-x

16557  Matsura T, Togawa A, Kai M, Nishida T, Nakada J, Ishibe Y, Kojo S, Yamamoto Y, Yamada K.  The presence of oxidized phosphatidylserine on Fas-mediated apoptotic cell surface  Biochim Biophys Acta  2005  1736(3):181-8  PubMed ID: 16168707   DOI: 10.1016/j.bbalip.2005.08.011

16606  Hattori N, Ikekubo K, Nakaya Y, Kitagawa K, Inagaki C.  Immunoglobulin G subclasses and prolactin (PRL) isoforms in macroprolactinemia due to anti-PRL autoantibodies  J Clin Endocrinol Metab  2005  90(5):3036-44  PubMed ID: 15687336   DOI: 10.1210/jc.2004-1600

2823  Yamauchi, Ritsuko, Morita, Akimichi, Yasuda, Yoko, Grether-Beck, Susanne, Klotz, Lars-Oliver, Tsuji, Takuo, Krutmann, Jean  Different susceptibility of malignant versus nonmalignant human T cells toward ultraviolet A-1 radiation-induced apoptosis.  J Invest Dermatol  2004  122:477-83  PubMed ID: 15009733   DOI: 10.1046/j.0022-202X.2003.22106.x

2894  Ito, Akio, Sasaguri, Yasuyuki, Kitada, Sakae, Kusaka, Yoshitomo, Kuwano, Kyoko, Masutomi, Kenjiro, Mizuki, Eiichi, Akao, Tetsuyuki, Ohba, Michio  A Bacillus thuringiensis crystal protein with selective cytocidal action to human cells.  J Biol Chem  2004  279:21282-6  PubMed ID: 15026424   DOI: 10.1074/jbc.M401881200

3403  Ozaki, Kouichi, Inoue, Katsumi, Sato, Hiroshi, Iida, Aritoshi, Ohnishi, Yozo, Sekine, Akihiro, Sato, Hideyuki, Odashiro, Keita, Nobuyoshi, Masakiyo, Hori, Masatsugu, Nakamura, Yusuke, Tanaka, Toshihiro  Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.  Nature  2004  429:72-5  PubMed ID: 15129282   DOI: 10.1038/nature02502

3340  Watanabe, Dai, Ezoe, Sachiko, Fujimoto, Minoru, Kimura, Akihiro, Saito, Yoshiyuki, Nagai, Hisaki, Tachibana, Isao, Matsumura, Itaru, Tanaka, Toshio, Kanegane, Hirokazu, Miyawaki, Toshio, Emi, Mitsuru, Kanakura, Yuzuru, Kawase, Ichiro, Naka, Tetsuji, Kishimoto, Tadamitsu  Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines.  Br J Haematol  2004  126:726-35  PubMed ID: 15327527   DOI: 10.1111/j.1365-2141.2004.05107.x

2863  Watanabe M, Kitano T, Kondo T, Yabu T, Taguchi Y, Tashima M, Umehara H, Domae N, Uchiyama T, Okazaki T.  Increase of nuclear ceramide through caspase-3-dependent regulation of the "sphingomyelin cycle" in Fas-induced apoptosis.  Cancer Res  2004  64(3):1000-7  PubMed ID: 14871831   DOI: 10.1158/0008-5472.can-03-1383

2884  Miyoshi N, Uchida K, Osawa T, Nakamura Y.  A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation.  Cancer Res  2004  64(6):2134-42  PubMed ID: 15026354   DOI: 10.1158/0008-5472.can-03-2296

2912  Eda S, Yamanaka M, Beppu M.  Carbohydrate-mediated phagocytic recognition of early apoptotic cells undergoing transient capping of CD43 glycoprotein.  J Biol Chem  2004  279(7):5967-74  PubMed ID: 14613931   DOI: 10.1074/jbc.M310805200

13799  Enomoto M, Endo D, Kawashima S, Park MK.  Human type II GnRH receptor mediates effects of GnRH on cell proliferation  Zoolog Sci  2004  21(7):763-70  PubMed ID: 15277720   DOI: 10.2108/zsj.21.763

13800  Enomoto M, Seong JY, Kawashima S, Park MK.  Proliferation of TSU-Pr1, a human prostatic carcinoma cell line is stimulated by gonadotropin-releasing hormone  Life Sci . 2004 May 7;74(25):3141-52  2004  74(25):3141-52  PubMed ID: 15081579   DOI: 10.1016/j.lfs.2003.11.009

2549  Nagai, Fusako, Hiyoshi, Yasuko, Sugimachi, Kumiko, Tamura, Hiro-Omi  Cytochrome P450 (CYP) expression in human myeloblastic and lymphoid cell lines.  Biol Pharm Bull  2002  25:383-5  PubMed ID: 11913539   DOI: 10.1248/bpb.25.383

2819  Uchida E, Mizuguchi H, Ishii-Watabe A, Hayakawa T.  Comparison of the efficiency and safety of non-viral vector-mediated gene transfer into a wide range of human cells.  Biol Pharm Bull  2002  25(7):891-7  PubMed ID: 12132664   DOI: 10.1248/bpb.25.891

13865  Jiang B, Hattori N, Liu B, Kitagawa K, Inagaki C.  Expression of swelling- and/or pH-regulated chloride channels (ClC-2, 3, 4 and 5) in human leukemic and normal immune cells  Life Sci  2002  70(12):1383-94  PubMed ID: 11883714   DOI: 10.1016/s0024-3205(01)01517-x

13869  Mizuguchi H, Hayakawa T.  Adenovirus vectors containing chimeric type 5 and type 35 fiber proteins exhibit altered and expanded tropism and increase the size limit of foreign genes  Gene  2002  285(1-2):69-77.  PubMed ID: 12039033   DOI: 10.1016/s0378-1119(02)00410-9

9032  N Kiyokawa, T Mori, T Taguchi, M Saito, K Mimori, T Suzuki, T Sekino, N Sato, H Nakajima, Y U Katagiri, T Takeda, J Fujimoto  Activation of the Caspase Cascade During Stx1-induced Apoptosis in Burkitt's Lymphoma Cells  J Cell Biochem  2001  81 (1), 128-42  PubMed ID: 11180403   DOI: 10.1002/1097-4644(20010401)81:1<128::aid-jcb1029>3.0.co;2-g

16955  Ando Y, Kuroda M, Honda O, Asaumi J, Okumura Y, Takeda Y, Akaki S, Kanazawa S, Kawasaki S, Hiraki Y.  The effect of calcium on Fas-mediated apoptosis and secondary necrosis of Jurkat cells  Int J Mol Med  2001  7(3):243-7  PubMed ID: 11179501   DOI: 10.3892/ijmm.7.3.243

16966  Masahiro KURODA, Yadi WANG, Megumi KOMATSU, Junichi ASAUMI, Koh-ichi SHIBUYA, Shoji KAWASAKI, Yoshihiro OKUMURA, Shiro AKAKI, SUSUMU KANAZAWA, Osamu HONDA, Yoshio HIRAKI  APPLICATION OF A NEW FLUORESCENT MICROSCOPIC SYSTEM FOR RESEARCH IN RADIATION BIOLOGY  The Journal of JASTRO  2001  13:119-124    DOI: 10.11182/jastro1989.13.119

13864  Fujino T, Tada T, Hosaka T, Beppu M, Kikugawa K.  Presence of oxidized protein hydrolase in human cell lines, rat tissues, and human/rat plasma  J Biochem  2000  127(2):307-13  PubMed ID: 10731698   DOI: 10.1093/oxfordjournals.jbchem.a022608

17274  Honda O, Kuroda M, Joja I, Asaumi J, Takeda Y, Akaki S, Togami I, Kanazawa S, Kawasaki S, Hiraki Y.  Assessment of secondary necrosis of Jurkat cells using a new microscopic system and double staining method with annexin V and propidium iodide  Int J Oncol  2000  16(2):283-8  PubMed ID: 10639571   DOI: 10.3892/ijo.16.2.283

17279  Ando K, Hagiwara T, Beppu M, Kikugawa K.  Naturally occurring anti-band 3 antibody binds to apoptotic human T-lymphoid cell line Jurkat through sialylated poly-N-acetyllactosaminyl saccharide chains on the cell surface  Biochem Biophys Res Commun  2000  275(2):412-7  PubMed ID: 10964679   DOI: 10.1006/bbrc.2000.3322

17280  Beppu M, Ando K, Saeki M, Yokoyama N, Kikugawa K.  Binding of oxidized Jurkat cells to THP-1 macrophages and antiband 3 IgG through sialylated poly-N-acetyllactosaminyl sugar chains  Arch Biochem Biophys  2000  384(2):368-74  PubMed ID: 11368325   DOI: 10.1006/abbi.2000.2122

11028  Y Tomita, T Kawasaki, V Bilim, M Takeda, K Takahashi  Tetrapeptide DEVD-aldehyde or YVAD-chloromethylketone inhibits Fas/Apo-1(CD95)-mediated apoptosis in renal-cell-cancer cells  Int J Cancer  1996  68(1):132-5  PubMed ID: 8895553   DOI: 10.1002/(SICI)1097-0215(19960927)68:1<132::AID-IJC23>3.0.CO;2-C

17221  Y. Tomita, V. Bilim, M. Takeda, K. Takahashi  Upregulation of Fas-induced apoptosis by interferon-? accompanied by increased ICE expression in renal cell cancer cells  Apoptosis  1996  1:209-212    DOI: 10.1007/bf01321104

6246  Ohsawa K, Watanabe Y, Sato H.  Hantaan virus persistently infects marmoset B-lymphoblastoid cell line.  J Vet Med Sci  1995  57(5):931-4  PubMed ID: 8593305   DOI: 10.1292/jvms.57.931