| 利用者成果(英) |
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19943
Koyama Y, Fujihara S, Chiyo T, Matsui T, Hamaya S, Fujita K, Tani J, Morishita A, Kobara H, Ono M, Iwama H, Masaki T.
Role of Mir-452-5p Overexpression in Epithelial-Mesenchymal Transition (EMT) in Early-stage Colorectal Cancer
In Vivo
2023
37(5):1980-1990
PubMed ID: 37652512
DOI: 10.21873/invivo.13295
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19975
Aiba T, Hijiya N, Akagi T, Tsukamoto Y, Hirashita Y, Kinoshita K, Uchida T, Nakada C, Kurogi S, Ueda Y, Shiroshita H, Shiraishi N, Murakami K, Inomata M, Moriyama M.
Overexpression of VSNL1 enhances cell proliferation in colorectal carcinogenesis
Pathobiology
2023
Oct 5
PubMed ID: 37797604
DOI: 10.1159/000533877
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20203
Kast F, Schwill M, Stüber JC, Pfundstein S, Nagy-Davidescu G, Rodríguez JMM, Seehusen F, Richter CP, Honegger A, Hartmann KP, Weber TG, Kroener F, Ernst P, Piehler J, Plückthun A.
Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action.
Nat Commun
2021
12(1):3790
PubMed ID: 34145240
DOI: 10.1038/s41467-021-23948-6
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15080
Hirashita Y, Tsukamoto Y, Kudo Y, Kakisako D, Kurogi S, Hijiya N, Nakada C, Uchida T, Hirashita T, Hiratsuka T, Akagi T, Ueda Y, Shiroshita H, Etoh T, Mizukami K, Honda K, Okimoto T, Kodama M, Inomata M, Moriyama M, Murakami K.
Early response in phosphorylation of ribosomal protein S6 is associated with sensitivity to trametinib in colorectal cancer cells
Lab Invest
2021
101(8):1036-1047
PubMed ID: 33911189
DOI: 10.1038/s41374-021-00590-w
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15088
Hanker AB, Brown BP, Meiler J, Marín A, Jayanthan HS, Ye D, Lin CC, Akamatsu H, Lee KM, Chatterjee S, Sudhan DR, Servetto A, Brewer MR, Koch JP, Sheehan JH, He J, Lalani AS, Arteaga CL.
Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity
Cancer Cell
2021
39(8):1099-1114.e8
PubMed ID: 34171264
DOI: 10.1016/j.ccell.2021.06.001
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9913
Satoshi Inoue, Takumi Tsunoda, Miho Riku, Hideaki Ito, Akihito Inoko, Hideki Murakami, Masahide Ebi, Naotaka Ogasawara, Ira Pastan, Kunio Kasugai, Kenji Kasai, Hiroshi Ikeda, Shingo Inaguma
Diffuse Mesothelin Expression Leads to Worse Prognosis Through Enhanced Cellular Proliferation in Colorectal Cancer
Oncol Lett
2020
19(3):1741-1750
PubMed ID: 32194667
DOI: 10.3892/ol.2020.11290
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11927
Yang J, Isaji T, Zhang G, Qi F, Duan C, Fukuda T, Gu J.
EpCAM associates with integrin and regulates cell adhesion in cancer cells.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31806375
DOI: 10.1016/j.bbrc.2019.11.152
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13234
Nishimoto A, Takemoto Y, Saito T, Kurazumi H, Tanaka T, Harada E, Shirasawa B, Hamano K.
Nuclear β-catenin expression is positively regulated by JAB1 in human colorectal cancer cells.
Biochem Biophys Res Commun
2020
PubMed ID: 32977947
DOI: 10.1016/j.bbrc.2020.09.007
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13325
Fernando TM, Piskol R, Bainer R, Sokol ES, Trabucco SE, Zhang Q, Trinh H, Maund S, Kschonsak M, Chaudhuri S, Modrusan Z, Januario T, Yauch RL.
Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients.
Nat Commun
2020
PubMed ID: 33144586
DOI: 10.1038/s41467-020-19402-8
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11342
Washio I, Nakanishi T, Ishiguro N, Bister B, Tamai I.
Effect of endogenous multidrug resistance 1 and P-glycoprotein expression on anticancer drug resistance in colon cancer cell lines.
Biopharm Drug Dispos
2019
PubMed ID: 30556139
DOI: 10.1002/bdd.2167
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11364
Kimura T, Tsukada A, Fukutomi T, Ichida K, Ohtsuki S, Sakurai H.
Urate Transport via Paracellular Route across Epithelial Cells.
Biol. Pharm. Bull.
2019
PubMed ID: 30606989
DOI: 10.1248/bpb.b18-00505
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11553
Wu Z, Ichinose T, Naoe Y, Matsumura S, Villalobos IB, Eissa IR, Yamada S, Miyajima N, Morimoto D, Mukoyama N, Nishikawa Y, Koide Y, Kodera Y, Tanaka M, Kasuya H.
Combination of Cetuximab and Oncolytic Virus Canerpaturev Synergistically Inhibits Human Colorectal Cancer Growth.
Mol Ther Oncolytics
2019
PubMed ID: 31193737
DOI: 10.1016/j.omto.2019.04.004
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11832
Robichaux JP, Elamin YY, Vijayan RSK, Nilsson MB, Hu L, He J, Zhang F, Pisegna M, Poteete A, Sun H, Li S, Chen T, Han H, Negrao MV, Ahnert JR, Diao L, Wang J, Le X, Meric-Bernstam F, Routbort M, Roeck B, Yang Z, Raymond VM, Lanman RB, Frampton GM, Miller VA, Schrock AB, Albacker LA, Wong KK, Cross JB, Heymach JV.
Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity.
Cancer Cell
2019
PubMed ID: 31588020
DOI: 10.1016/j.ccell.2019.09.001
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4178
Ichimanda M, Hijiya N, Tsukamoto Y, Uchida T, Nakada C, Akagi T, Etoh T, Iha H, Inomata M, Takekawa M, Moriyama M.
Downregulation of dual-specificity phosphatase 4 enhances cell proliferation and invasiveness in colorectal carcinomas.
Cancer Sci.
2018
PubMed ID: 29150975
DOI: 10.1111/cas.13444
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10398
Matsushita N, Yamamoto S, Inoue Y, Aruga A, Yamamoto M.
RT-qPCR analysis of the tumor antigens TOMM34 and RNF43 in samples extracted from paraffin-embedded specimens of colorectal cancer.
Oncol Lett
2017
14:2281-2287
PubMed ID: 28789449
DOI: 10.3892/ol.2017.6412
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10498
Inaguma S, Lasota J, Felisiak-Golabek A, Kowalik A, Wang Z, Zieba S, Kalisz J, Ikeda H, Miettinen M.
Histopathological and genotypic characterization of metastatic colorectal carcinoma with PD-L1 (CD274)-expression: Possible roles of tumour micro environmental factors for CD274 expression.
J Pathol Clin Res
2017
3:268-278
PubMed ID: 29085667
DOI: 10.1002/cjp2.81
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14055
Morishita S, Suzuki T, Niwa Y, Dohmae N, Simizu S.
Dpy-19 like 3-mediated C-mannosylation and expression levels of RPE-spondin in human tumor cell lines
Oncol Lett
2017
14(2):2537-2544
PubMed ID: 28781692
DOI: 10.3892/ol.2017.6465
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9508
Kaku Y, Tsuchiya A, Shimizu T, Tanaka A, Nishizaki T.
HUHS1015 Suppresses Colonic Cancer Growth by Inducing Necrosis and Apoptosis in Association with Mitochondrial Damage.
Anticancer Res.
2016
36:39-48
PubMed ID: 26722026
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9823
Novotny CJ, Pollari S, Park JH, Lemmon MA, Shen W, Shokat KM.
Overcoming resistance to HER2 inhibitors through state-specific kinase binding.
Nat. Chem. Biol.
2016
12:923-930
PubMed ID: 27595329
DOI: 10.1038/nchembio.2171
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15077
Kloth M, Ruesseler V, Engel C, Koenig K, Peifer M, Mariotti E, Kuenstlinger H, Florin A, Rommerscheidt-Fuss U, Koitzsch U, Wodtke C, Ueckeroth F, Holzapfel S, Aretz S, Propping P, Loeffler M, Merkelbach-Bruse S, Odenthal M, Friedrichs N, Heukamp LC, Zander T, Buettner R.
Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer
Gut
2016
65(8):1296-305
PubMed ID: 26001389
DOI: 10.1136/gutjnl-2014-309026
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7334
Ito H, Hasegawa K, Hasegawa Y, Nishimaki T, Hosomichi K, Kimura S, Ohba M, Yao H, Onimaru M, Inoue I, Inoue H.
Silver Nanoscale Hexagonal Column Chips for Detecting Cell-free DNA and Circulating Nucleosomes in Cancer Patients.
Sci Rep
2015
5:10455
PubMed ID: 25994878
DOI: 10.1038/srep10455
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7414
Kaku Y, Tsuchiya A, Kanno T, Nishizaki T.
Irinotecan induces cell cycle arrest, but not apoptosis or necrosis, in Caco-2 and CW2 colorectal cancer cell lines.
Pharmacology
2015
95:154-9
PubMed ID: 25833236
DOI: 10.1159/000381029
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10158
Takuma Yoshinaga, Takamasa Shigemitsu, Hiroto Nishimata, Masaki Kitazono, Emiko Hori, Ayako Tomiyoshi, Takayuki Takei, Masahiro Yoshida
Angiopoietin-like Protein 2 as a Potential Biomarker for Colorectal Cancer
Mol Clin Oncol
2015
3(5):1080-1084
PubMed ID: 26623054
DOI: 10.3892/mco.2015.577
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15087
Kauko O, Laajala TD, Jumppanen M, Hintsanen P, Suni V, Haapaniemi P, Corthals G, Aittokallio T, Westermarck J, Imanishi SY.
Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling
Sci Rep
2015
5:13099
PubMed ID: 26278961
DOI: 10.1038/srep13099
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10244
Kazuhiro Ishiguro, Takafumi Ando, Osamu Maeda, Osamu Watanabe, Hidemi Goto
Suppressive Action of Acetate on interleukin-8 Production via Tubulin-α Acetylation
Immunol Cell Biol
2014
92(7):624-30
PubMed ID: 24777307
DOI: 10.1038/icb.2014.31
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15079
Ålgars A, Avoranta T, Österlund P, Lintunen M, Sundström J, Jokilehto T, Ristimäki A, Ristamäki R, Carpén O.
Heterogeneous EGFR gene copy number increase is common in colorectal cancer and defines response to anti-EGFR therapy
PLoS One
2014
9(6):e99590
PubMed ID: 24940619
DOI: 10.1371/journal.pone.0099590
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15086
Katase N, Lefeuvre M, Tsujigiwa H, Fujii M, Ito S, Tamamura R, Buery RR, Gunduz M, Nagatsuka H.
Knockdown of Dkk-3 decreases cancer cell migration and invasion independently of the Wnt pathways in oral squamous cell carcinoma‑derived cells
Oncol Rep
2013
29(4):1349-55
PubMed ID: 23354949
DOI: 10.3892/or.2013.2251
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6316
Miyaki Y, Suzuki K, Koizumi K, Kato T, Saito M, Kamiyama H, Maeda T, Shibata K, Shiya N, Konishi F.
Identification of a potent epigenetic biomarker for resistance to camptothecin and poor outcome to irinotecan-based chemotherapy in colon cancer.
Int J Oncol
2012
40(1):217-26
PubMed ID: 21901246
DOI: 10.3892/ijo.2011.1189
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6317
Koizumi K, Alonso S, Miyaki Y, Okada S, Ogura H, Shiiya N, Konishi F, Taya T, Perucho M, Suzuki K.
Array-based identification of common DNA methylation alterations in ulcerative colitis.
Int J Oncol
2012
40(4):983-94
PubMed ID: 22159500
DOI: 10.3892/ijo.2011.1283
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15078
Hanada N, Takahata T, Zhou Q, Ye X, Sun R, Itoh J, Ishiguro A, Kijima H, Mimura J, Itoh K, Fukuda S, Saijo Y.
Methylation of the KEAP1 gene promoter region in human colorectal cancer
BMC Cancer
2012
12:66
PubMed ID: 22325485
DOI: 10.1186/1471-2407-12-66
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15085
Hasegawa M, Ishiguro K, Ando T, Goto H.
Geranylgeranylacetone attenuates cisplatin-induced reductions in cell viability by suppressing the elevation of intracellular p53 content without heat shock protein induction
Nagoya J Med Sci
2012
74(1-2):123-31
PubMed ID: 22515118
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7823
Matsuo T, Nishizuka SS, Ishida K, Iwaya T, Ikeda M, Wakabayashi G.
Analysis of the anti-tumor effect of cetuximab using protein kinetics and mouse xenograft models.
BMC Res Notes
2011
4:140
PubMed ID: 21554739
DOI: 10.1186/1756-0500-4-140
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15083
Noriko Yoshikawa, Arisa Nishiuchi, Erika Kubo, Yu Yamaguchi, Masaru Kunitomo, Satomi Kagota, Kazumasa Shinozuka, Kazuki Nakamura
Cordyceps sinensis Acts as an Adenosine A3 Receptor Agonist on Mouse Melanoma and Lung Carcinoma Cells, and Human Fibrosarcoma and Colon Carcinoma Cells
Pharmacology & Pharmacy
2011
2:266-270
DOI: 10.4236/pp.2011.24034
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8475
Saito M, Yaguchi T, Yasuda Y, Nakano T, Nishizaki T.
Adenosine suppresses CW2 human colonic cancer growth by inducing apoptosis via A(1) adenosine receptors.
Cancer Lett.
2010
290:211-5
PubMed ID: 19822392
DOI: 10.1016/j.canlet.2009.09.011
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5882
Shichiri M, Fukai N, Kono Y, Tanaka Y.
Rifampicin as an oral angiogenesis inhibitor targeting hepatic cancers.
Cancer Res
2009
69(11):4760-8
PubMed ID: 19458074
DOI: 10.1158/0008-5472.CAN-08-3417
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6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
DOI: 10.1111/j.1749-0774.2009.00071.x
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18148
Ishiguro K, Ando T, Goto H.
Novel application of 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole to visualize lysosomes in live cells
Biotechniques
2008
45(4):465, 467-8
PubMed ID: 18855774
DOI: 10.2144/000112912
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9428
Chirila T, Barnard Z, Zainuddin, Harkin DG, Schwab IR, Hirst L.
Bombyx mori silk fibroin membranes as potential substrata for epithelial constructs used in the management of ocular surface disorders.
Tissue Eng Part A
2008
14(7):1203-11
PubMed ID: 18380593
DOI: 10.1089/ten.tea.2007.0224
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15084
Maeda O, Kondo M, Fujita T, Usami N, Fukui T, Shimokata K, Ando T, Goto H, Sekido Y.
Enhancement of GLI1-transcriptional activity by beta-catenin in human cancer cells
Oncol Rep
2006
16(1):91-6
PubMed ID: 16786128
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8943
Sun L, Fu BB, Liu DG.
Systemic delivery of full-length C/EBP beta/liposome complex suppresses growth of human colon cancer in nude mice.
Cell Res.
2005
15:770-6
PubMed ID: 16246266
DOI: 10.1038/sj.cr.7290346
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18147
Hara M, Adachi S, Higuchi A.
Enhanced production of carcinoembryonic antigen by CW-2 cells cultured on polymeric membranes immobilized with extracellular matrix proteins
J Biomater Sci Polym Ed
2003
14(2):139-55
PubMed ID: 12661665
DOI: 10.1163/156856203321142588
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3762
Kataoka H, Itoh H, Uchino H, Hamasuna R, Kitamura N, Nabeshima K, Koono M.
Conserved expression of hepatocyte growth factor activator inhibitor type-2/placental bikunin in human colorectal carcinomas.
Cancer Lett
2000
148(2):127-34
PubMed ID: 10695988
DOI: 10.1016/s0304-3835(99)00322-5
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18149
Higuchi A, Uchiyama S, Demura M, Asakura T, Cho CS, Akaike T, Takarada H, Hara M.
Enhanced CEA production associated with aspirin in a culture of CW-2 cells on some polymeric films
Cytotechnology
1999
31(3):233-42
PubMed ID: 19003147
DOI: 10.1023/A:1008030730814
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18150
Kono T, Watanabe M, Koyama K, Kishimoto T, Fukushima S, Sugimura T, Wakabayashi K.
Cytotoxic activity of pierisin, from the cabbage butterfly, Pieris rapae, in various human cancer cell lines
Cancer Lett
1999
137(1):75-81
PubMed ID: 10376796
DOI: 10.1016/s0304-3835(98)00346-2
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18151
Ueda T, Furui J, Komuta K, Yamaguchi J, Yamamoto M, Furukawa K, Kanematsu T.
Detection of carcinoembryonic antigen mRNA in the mesenteric vein of patients with resectable colorectal cancer
Surg Today
1998
28(7):701-6
PubMed ID: 9697262
DOI: 10.1007/BF02484615
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3754
Nabeshima K, Shimao Y, Inoue T, Itoh H, Kataoka H, Koono M.
Hepatocyte growth factor/scatter factor induces not only scattering but also cohort migration of human colorectal-adenocarcinoma cells.
Int J Cancer
1998
78(6):750-9
PubMed ID: 9833769
DOI: 10.1002/(sici)1097-0215(19981209)78:6<750::aid-ijc13>3.0.co;2-#
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3755
Kataoka H, Uchino H, Denda K, Kitamura N, Itoh H, Tsubouchi H, Nabeshima K, Koono M.
Evaluation of hepatocyte growth factor activator inhibitor expression in normal and malignant colonic mucosa.
Cancer Lett
1998
19;128(2):219-27
PubMed ID: 9683286
DOI: 10.1016/s0304-3835(98)00067-6
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3752
Kataoka H, Uchino H, Asada Y, Hatakeyama K, Nabeshima K, Sumiyoshi A, Koono M.
Analysis of tissue factor and tissue factor pathway inhibitor expression in human colorectal carcinoma cell lines and metastatic sublines to the liver.
Int J Cancer
1997
72(5):878-84
PubMed ID: 9311608
DOI: 10.1002/(sici)1097-0215(19970904)72:5<878::aid-ijc27>3.0.co;2-3
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