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Cell No. : Cell Name
RCB0763 : GI-1  update : 2022/08/24
CommentHuman glioma separated from gliosarcoma.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Nakatu, Syouji
Originator Iwasaki, Kouji
Year of deposit 1992
Animal human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Male
Age at sampling 61 years
Tissue brain
Disease name gliosarcoma
Metastastatic ability No
Classification cancer
Memo_1 Mycoplasma was eliminated with MC-210 by the depositor.
Lifespan infinite
Morphology fibroblast-like
Cellosaurus(Expasy) CVCL_1231
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives DMEM (low glucose) + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Virus (HIV) (-)
Isozyme LD, NP
Chromosome mode 81-194(50) : /93(4),94(4),95(3),96(4),97(4),98(6)/
STR(human) OK
Images
deposit info
lot info
Reference information Reference 4
User's Publication 15


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Reference
1587  Iwasaki K, Kikuchi H, Miyatake S, Kondo S, Oda Y  Establishment of a new cell line derived from a human gliosarcoma.  Neurosurgery  1992  30:228-35  PubMed ID: 1545891   DOI: 10.1227/00006123-199202000-00013
4812  Miyatake S, Kondou S, Aoki T, Iwasaki K, Ohyama K, Ootsuka S, Oda Y, Kikuchi H.  Immunomodulatory effects of interferons on target human gliosarcoma cells in the tumor-specific CTL- and LAK-mediated cytolysis]  No Shinkei Geka  1991  19(11):1053-9  PubMed ID: 1762655  
4811  Miyatake S, Kikuchi H, Oda Y, Nishioka T, Takahashi J, Kondoh S, Matsumoto M, Yamasaki T, Iwasaki K, Aoki T, et al.  Decreased susceptibility of lined human gliosarcoma cells to lymphokine-activated killer cell cytolysis by gamma-interferon treatment.  Cancer Res  1990  50(3):596-600  PubMed ID: 2137025  
4810  Miyatake S, Kikuchi H, Iwasaki K, Yamashita J, Li ZY, Namba Y, Hanaoka M.  Specific cytotoxic activity of T lymphocyte clones derived from a patient with gliosarcoma.  J Neurosurg  1988  69(5):751-9  PubMed ID: 3263476   DOI: 10.3171/jns.1988.69.5.0751

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User's Publication
16701  Chinen T, Yamazaki K, Hashimoto K, Fujii K, Watanabe K, Takeda Y, Yamamoto S, Nozaki Y, Tsuchiya Y, Takao D, Kitagawa D.  Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly  J Cell Biol  2021  220(2):e202006085  PubMed ID: 33443571   DOI: 10.1083/jcb.202006085
11920  Takumi Chinen , Shohei Yamamoto, Yutaka Takeda , Koki Watanabe, Kanako Kuroki , Kaho Hashimoto , Daisuke Takao , Daiju Kitagawa  NuMA assemblies organize microtubule asters to establish spindle bipolarity in acentrosomal human cells  EMBO J  2020    PubMed ID: 31782546   DOI: 10.15252/embj.2019102378
11511  Behan FM, Iorio F, Picco G, Gonçalves E, Beaver CM, Migliardi G, Santos R, Rao Y, Sassi F, Pinnelli M, Ansari R, Harper S, Jackson DA, McRae R, Pooley R, Wilkinson P, van der Meer D, Dow D, Buser-Doepner C, Bertotti A, Trusolino L, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ.  Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.  Nature  2019    PubMed ID: 30971826   DOI: 10.1038/s41586-019-1103-9
12337  Agarwal S, Mohamed MS, Mizuki T, Maekawa T, Sakthi Kumar D.  Chlorotoxin modified morusin-PLGA nanoparticles for targeted glioblastoma therapy  J Mater Chem B  2019  7(39):5896-5919  PubMed ID: 31423502   DOI: 10.1039/c9tb01131e
9629  Sakai S, Maruyama H, Kimura T, Tajiri K, Honda J, Homma S, Aonuma K, Miyauchi T.  Antagonists to endothelin receptor type B promote apoptosis in human pulmonary arterial smooth muscle cells.  Life Sci.  2016  159:116-120  PubMed ID: 27021787   DOI: 10.1016/j.lfs.2016.03.044
15425  Sreejith Raveendran, Neha Chauhan, Vivekanandan Palaninathan, Yutaka Nagaoka, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar  Extremophilic Polysaccharide for Biosynthesis and Passivation of Gold Nanoparticles and Photothermal Ablation of Cancer Cells  Particle & Particle Systems Characterization  2015  32:54-64    DOI: 10.1002/ppsc.201400081
16168  Ravindran Girija Aswathy, Balasubramanian Sivakumar, Dhandayudhapani Brahatheeshwaran, Tomofumi Ukai, Yasuhiko Yoshida, Toru Maekawa, Sakthi D. Kumar  Biocompatible Fluorescent Jelly Quantum Dots for Bioimaging  Materials Express  2011  1:291-298    DOI: 10.1166/mex.2011.1045
14417  Sano M, Genkai N, Yajima N, Tsuchiya N, Homma J, Tanaka R, Miki T, Yamanaka R.  Expression level of ECT2 proto-oncogene correlates with prognosis in glioma patients  Oncol Rep  2006  16(5):1093-8  PubMed ID: 17016598  
14418  Homma J, Yamanaka R, Yajima N, Tsuchiya N, Genkai N, Sano M, Tanaka R.  Increased expression of CCAAT/enhancer binding protein beta correlates with prognosis in glioma patients  Oncol Rep  2006  15(3):595-601  PubMed ID: 16465418  
2958  Awata T, Kurihara S, Takata N, Neda T, Iizuka H, Ohkubo T, Osaki M, Watanabe M, Nakashima Y, Inukai K, Inoue I, Kawasaki I, Mori K, Yoneya S, Katayama S  Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes.  Biochem Biophys Res Commun  2005  333:679-85  PubMed ID: 15963467   DOI: 10.1016/j.bbrc.2005.05.167
15603  Guleng B, Tateishi K, Ohta M, Asaoka Y, Jazag A, Lin LJ, Tanaka Y, Tada M, Seto M, Kanai F, Kawabe T, Omata M.  Identification of an epigenetically silenced gene, RFX1, in human glioma cells using restriction landmark genomic scanning  Oncogene  2004  23(47):7772-9  PubMed ID: 15334059   DOI: 10.1038/sj.onc.1208058
2959  Lambrechts, Diether, Storkebaum, Erik, Morimoto, Masafumi, Del-Favero, Jurgen, Desmet, Frederik, Marklund, Stefan L, Wyns, Sabine, Thijs, Vincent, Andersson, Jorgen, van Marion, Ingrid, Al-Chalabi, Ammar, Bornes, Stephanie, Musson, Rhiannon, Hansen, Valerie, Beckman, Lars, Adolfsson, Rolf, Pall, Hardev Singh, Prats, Herve, Vermeire, Severine, Rutgeerts, Paul, Katayama, Shigehiro, Awata, Takuya, Leigh, Nigel, Lang-Lazdunski, Loic, Dewerchin, Mieke, Shaw, Christopher, Moons, Lieve, Vlietinck, Robert, Morrison, Karen E, Robberecht, Wim, Van Broeckhoven, Christine, Collen, Desire, Andersen, Peter M, Carmeliet, Peter  VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death.  Nat Genet  2003  34:383-94  PubMed ID: 12847526   DOI: 10.1038/ng1211
2550  Tamura, H O, Taniguchi K, Hayashi E, Hiyoshi Y, Nagai F  Expression profiling of sulfotransferases in human cell lines derived from extra-hepatic tissues.  Biol Pharm Bull  2001  24:1258-62  PubMed ID: 11725959   DOI: 10.1248/bpb.24.1258
16388  S. Yoshida, K. Fukino, H. Harada, H. Nagai, I. Imoto, J. Inazawa, H. Takahashi, A. Teramoto, M. Emi  The c-Jun NH2-terminal kinase3 (JNK3) gene: genomic structure, chromosomal assignment, and loss of expression in brain tumors  Journal of Human Genetics  2001  42:182-187  PubMed ID: 11322657   DOI: 10.1007/s100380170086
4988  Kuramoto T.  Detection of MAGE-1 tumor antigen in brain tumor.  Kurume Med J  1997  44(1):43-51  PubMed ID: 9154761   DOI: 10.2739/kurumemedj.44.43


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