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Cell No. : Cell Name
RCB0753 : OMC-1  update : 2024/05/02
CommentJapanese cervix squamous cell carcinoma. Once said TA-4 positive.
Comment from the depositor
Terms and conditionsA prior written permission of the approver(Depositor) is necessary for any kind of use including academic use and for-profit use.
approver's address
Kio University Graduate School
4-2-2 Umaminaka, Koryo, kitakatsuragi, Nara, 653-0832 Japan
Dr.UEDA Masatsugu
Fax. +81-745-54-1600
Order Form Order Form(C-0005.pdf)   Approval Form(C-0006.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Ueda, Masatsugu
Originator Ueda, Masatsugu
Year of deposit 1992
Animal _human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Female
Age at sampling 52 years
Tissue cervix, Virchow's lymph node
Disease name uterine cervical cancer cell
Metastatic ability Yes
Metastatic tissue Virchow's lymph node
Classification cancer
Year of origin 1984
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_1623
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Culture medium HamF12 + 20% NBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : once/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Virus (HIV) (-)
Isozyme LD, NP
Chromosome mode 40-94(50) : /44(3),45(7),46(18),47(14),48(2),49(1)/
STR(human) OK
deposit info
lot info
Reference information Reference 11
User's Publication 1

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885  Ueda M, Hung YC, Chen JT, Chiou SH, Huang HH, Lin TY, Terai Y, Chow KC.  Infection of human papillomavirus and overexpression of dihydrodiol dehydrogenase in uterine cervical cancer  Gynecol Oncol  2006  102(2):173-81  PubMed ID: 16427687   DOI: 10.1016/j.ygyno.2005.12.009
882  Ueda M, Hung YC, Terai Y, Yamaguchi H, Saito J, Nunobiki O, Noda S, Ueki M.  Fas gene promoter -670 polymorphism (A/G) is associated with cervical carcinogenesis  Gynecol Oncol  2005  98(1):129-33  PubMed ID: 15894356   DOI: 10.1016/j.ygyno.2005.04.001
884  Ueda M, Terai Y, Yamashita Y, Kumagai K, Ueki K, Yamaguchi H, Akise D, Hung YC, Ueki M.  Correlation between vascular endothelial growth factor-C expression and invasion phenotype in cervical carcinomas  Int J Cancer  2002  98(3):335-43  PubMed ID: 11920583   DOI: 10.1002/ijc.10193
883  Ueda M, Terai Y, Kumagai K, Ueki K, Kanemura M, Ueki M.  Correlation between thymidine phosphorylase expression and invasion phenotype in cervical carcinoma cells  Int J Cancer  2001  91(6):778-82  PubMed ID: 11275979   DOI: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1133>;2-s
2340  Ueda M, Kumagai K, Ueki K, Inoki C, Orino I, Ueki M  Growth inhibition and apoptotic cell death in uterine cervical carcinoma cells induced by 5-fluorouracil.  Int J Cancer  1997  71:668-74  PubMed ID: 9178824   DOI: 10.1002/(sici)1097-0215(19970516)71:4<668::aid-ijc25>;2-6
75  Ueda M, Ueki M, Fujii H, Yoshizawa K, Nakajima M.  Inhibitory effects of ubenimex (bestatin) on the invasion of uterine cervical carcinoma cells and their production and activation of gelatinase A  J Med  1997  28(3-4):175-90  PubMed ID: 9355022  
78  Ueda M, Seiki Y, Yamada T, Okamoto Y, Tsurunaga T, Iwai E, Ueki M, Sugimoto O.  In vitro studies on the expression of c-myc oncogene product in gynecological cultured cancer cells  Nihon Sanka Fujinka Gakkai Zasshi  1991  43(11):1489-95  PubMed ID: 1940543  
1737  Ueda M, Ueki M, Yamada T, Okamoto Y, Maeda T, Sugimoto O, Otsuki Y  Scatchard analysis of EGF receptor and effects of EGF on growth and TA-4 production of newly established uterine cervical cancer cell line (OMC-1).  Hum Cell  1989  2:401-10  PubMed ID: 2486664  
77  Ueda M, Misaki O, Yamada T, Okamoto Y, Goto M, Maeda T, Okamura S, Ueki M, Sugimoto O.  In vitro studies of 5-FU sensitivity on uterine cervical cancer cell lines--comparison between squamous cell carcinoma and adenocarcinoma  Nihon Sanka Fujinka Gakkai Zasshi  1989  41(9):1423-30  PubMed ID: 2531191  
76  Ueda M, Ueki M, Fujii H, Yoshizawa K, Nakajima M.  EGF receptor and effects of EGF on growth and tumor marker secretion in uterine cervical cancer cells  Nihon Sanka Fujinka Gakkai Zasshi  1988  40(11):1700-6  PubMed ID: 3266224  
74  Ueda M, Maeda T, Yamada T, Miyawaki Y, Otsuki Y, Okamoto Y, Okamura S, Sano T, Ueki M, Sugimoto O.  Establishment and characterization of TA-4 producing cell line (OMC-1) originating from a human squamous cell carcinoma of the uterine cervix  Nihon Sanka Fujinka Gakkai Zasshi  1986  38(7):1071-8  PubMed ID: 3746026  

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User's Publication
6410  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Is parainfluenza virus a threatening virus for human cancer cell lines?  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309   DOI: 10.1111/j.1749-0774.2009.00071.x

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