Cell No. : Cell Name RCB0688 : QG-U  update : 2022/07/07
Comment			Japanese cervix carcinoma.
Comment from the depositor
Terms and conditions			There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form			Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)
			Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
	Basic information	Depositor	Mashiba, Harukazu
		Originator	Mashiba, Harukazu
		Year of deposit	1991
		Animal	_human < Mammals
		Genus	Homo
		Species	sapiens
		Race	Japanese
		Gender	Female
		Tissue	cervix
		Disease name	cervix carcinoma
		Classification	cancer
		Year of origin	1974
		Memo_1	Mycoplasma was eliminated with MC-210.
		Lifespan	infinite
		Morphology	epithelial-like
		Cellosaurus(Expasy)	CVCL_3778
			deposit info	lot info
		Medium	Medium List
		Culture type		Adherent cells
		Culture medium		M199 + 15% FBS
		Antibiotics		Free
		Passage method		0.25% Trypsin
	Culture information	Passage ratio		1 : 8 split
		SC frequency		Subculture : once/week, Medium Renewal : 2 times/week
		Temperature		37 ℃
		CO2 concentration		5 %
		Freeze medium		Medium + 10% DMSO
		Freezing method		Slow freezing
		Mycoplasma/Acholeplasma		(-)
		Isozyme		LD, NP
		Chromosome mode		72-154(50) : 73(4),74(8),75(8),76(6),77(9),78(10)/
		STR(human)		OK
Reference information		Reference	4
		User's Publication	5

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Reference

53  Matsunaga K, Mashiba H, Kurano A, Jimi S.  Lymphotoxin production by regional lymph node lymphocytes in patients with uterine cervical cancer  J Clin Immunol  1990  10(5):265-7  PubMed ID: 2266150   DOI: 10.1007/BF00916702

52  Saito T, Jimi S, Watanabe Y, Kurano A, Mashiba H.  Immunologic parameters and prognosis in cervical cancer patients treated with radiotherapy  Asia Oceania J Obstet Gynaecol  1985  11(4):499-506  PubMed ID: 3879582

50  Matsunaga K, Mashiba H, Gojobori M.  Cytostatic activity of in vitro activated human adherent cells against human tumor cell lines  Gan  1980  71(1):73-9  PubMed ID: 6991350

51  Matsunaga K, Mashiba H, Gojobori M, Jimi S.  Antibody-dependent cell-mediated cytotoxicity of sera from cancer patients against cultured cervical cancer cell lines  Gan  1979  70(1):1-7  PubMed ID: 571828

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User's Publication

21167  Lin X, Yoshikawa N, Liu W, Matsukawa T, Nakamura K, Yoshihara M, Koya Y, Sugiyama M, Tamauchi S, Ikeda Y, Yokoi A, Shimizu Y, Kajiyama H.  DDIT4 Facilitates Lymph Node Metastasis via the Activation of NF-κB Pathway and Epithelial-Mesenchymal Transition.  Reprod Sci  2023    PubMed ID: 37016173   DOI: 10.1007/s43032-023-01230-y

5011  Nagura M, Matsumura N, Baba T, Murakami R, Kharma B, Hamanishi J, Yamaguchi K, Abiko K, Koshiyama M, Mandai M, Murata T, Murphy SK, Konishi I.  Invasion of uterine cervical squamous cell carcinoma cells is facilitated by locoregional interaction with cancer-associated fibroblasts via activating transforming growth factor-beta.  Gynecol Oncol  2015  136(1):104-11  PubMed ID: 25434636   DOI: 10.1016/j.ygyno.2014.11.075

6410  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Is parainfluenza virus a threatening virus for human cancer cell lines?  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309   DOI: 10.1111/j.1749-0774.2009.00071.x

17338  Suzuki T, Takimoto K.  Selective expression of HERG and Kv2 channels influences proliferation of uterine cancer cells  Int J Oncol  2004  25(1):153-9  PubMed ID: 15202000

17252  Masa-Aki Okubo, Akira Matsuno, Masayoshi Namba, Hiroshi Hosoya  A monoclonal antibody, mH1, specifically recognizes microvilli of dividing HeLa cells  Tiss Cult Res Commum  1999  18:113-117    DOI: 10.11418/jtca1981.18.1_113