細胞番号 : 細胞名
RCB0638 : TCS
update : 2022/07/07
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| 細胞特性(Comment:英) | Human cell line derived from uterine cervix cancer. Keratinizing squamous carcinoma. Said producing CEA. |
| 細胞特性(日) | ヒト子宮頸癌由来細胞株。角化型扁平上皮癌。CEA産生という。 |
| 細胞特性(寄託者記述:英) | |
| 細胞特性(寄託者記述:日) | |
| 使用条件(英) | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
| 使用条件(日) | 基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。 |
| 備考(英) | |
| 備考(日) | |
| 提供申込書類(英) |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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| 提供申込書類(日) |
依頼書C-0001.pdf
同意書(非営利学術目的)C-0003.pdf
同意書(営利目的)C-0003p.pdf
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提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください（詳細）。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
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| 提供手数料 |
手数料とお支払いについてはこちらをご覧ください。 |
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細胞基本情報
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寄託者 |
Izumi, Rikuichi
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| 樹立者 |
Izumi, Rikuichi & Kawabata, Masakiyo
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| 寄託日 |
1991
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| 別名 |
TC-S
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| 動物種 |
_human
< Mammals
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| 属名 |
Homo
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| 種名 |
sapiens
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| 人種 |
Japanese
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| 性別 |
Female
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| 齢 |
78 years
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| 採取組織 |
cervix, lymph node meta
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| 病名 |
large cell, keratinizing
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| 転移 |
Yes
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| 転移巣 |
lymph node
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| 細胞分類 |
cancer
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| 初代培養日 |
1982
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| メモ_1 |
Mycoplasma was eliminated with MC-210 by the depositor.
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|
細胞寿命 |
infinite
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| 細胞形態 |
epithelial-like
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| Cellosaurus(Expasy) |
CVCL_8160
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細胞培養・検査情報
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寄託時情報 |
ロット情報 |
| 培地・試薬情報 |
培地・試薬一覧はこちらをご覧ください。 |
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培養形態 |
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Adherent cells
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| 培地 |
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MEM + 10% FBS
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| 抗生物質 |
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Free
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|
継代方法 |
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0.25% Trypsin
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|
継代密度 |
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1 : 8 split
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| 継代・培地交換頻度 |
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Subculture : once/week, Medium Renewal : 2 times/week
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| 培養最適温度 |
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37
℃
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| 二酸化炭素濃度 |
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5
%
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| 凍結培地 |
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Medium + 10% DMSO
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| 凍結方法 |
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Slow freezing
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| マイコプラズマ |
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(-)
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| ウィルス（HIV) |
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(-)
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| アイソザイム検査 |
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LD, NP
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| 染色体検査 |
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89-180(50) : /83(2),84(3),85(5),86(5),87(5),88(3)/
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| 個体識別検査 |
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OK
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| 文献情報 |
Reference(英) |
1件
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| Reference(日) |
1件
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| 利用者成果(英) |
12件
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| 利用者成果(日) |
0件
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| 利用者成果(英) |
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21167
Lin X, Yoshikawa N, Liu W, Matsukawa T, Nakamura K, Yoshihara M, Koya Y, Sugiyama M, Tamauchi S, Ikeda Y, Yokoi A, Shimizu Y, Kajiyama H.
DDIT4 Facilitates Lymph Node Metastasis via the Activation of NF-κB Pathway and Epithelial-Mesenchymal Transition.
Reprod Sci
2023
PubMed ID: 37016173
DOI: 10.1007/s43032-023-01230-y
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7659
Murata T, Mizushima H, Chinen I, Moribe H, Yagi S, Hoffman RM, Kimura T, Yoshino K, Ueda Y, Enomoto T, Mekada E.
HB-EGF and PDGF mediate reciprocal interactions of carcinoma cells with cancer-associated fibroblasts to support progression of uterine cervical cancers.
Cancer Res.
2011
71:6633-42
PubMed ID: 22009535
DOI: 10.1158/0008-5472.CAN-11-0034
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6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
DOI: 10.1111/j.1749-0774.2009.00071.x
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18316
Yeasmin S, Nakayama K, Ishibashi M, Katagiri A, Iida K, Purwana IN, Nakayama N, Miyazaki K.
Expression of the bric-a-brac tramtrack broad complex protein NAC-1 in cervical carcinomas seems to correlate with poorer prognosis
Clin Cancer Res
2008
14(6):1686-91
PubMed ID: 18347169
DOI: 10.1158/1078-0432.CCR-07-4085
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9059
Y-C Jung, E Mizuki, T Akao, J-C Côté
Isolation and Characterization of a Novel Bacillus Thuringiensis Strain Expressing a Novel Crystal Protein With Cytocidal Activity Against Human Cancer Cells
J Appl Microbiol
2007
103 (1), 65-79
PubMed ID: 17584453
DOI: 10.1111/j.1365-2672.2006.03260.x
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3335
Yoshino K, Iimura E, Saijo K, Iwase S, Fukami K, Ohno T, Obata Y, Nakamura Y.
Essential role for gene profiling analysis in the authentication of human cell lines.
Hum Cell
2006
19(1):43-8
PubMed ID: 16643607
DOI: 10.1111/j.1749-0774.2005.00007.x
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3413
Yamashita, Satoko, Katayama, Hideki, Saitoh, Hiroyuki, Akao, Tetsuyuki, Park, Yu Shin, Mizuki, Eiichi, Ohba, Michio, Ito, Akio
Typical Three-Domain Cry Proteins of Bacillus thuringiensis Strain A1462 Exhibit Cytocidal Activity on Limited Human Cancer Cells.
J Biochem
2005
138:663-72
PubMed ID: 16428294
DOI: 10.1093/jb/mvi177
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18118
Terauchi M, Kajiyama H, Shibata K, Ino K, Mizutani S, Kikkawa F.
Anti-progressive effect of neutral endopeptidase 24.11 (NEP/CD10) on cervical carcinoma in vitro and in vivo
Oncology
2005
;69(1):52-62
PubMed ID: 16103735
DOI: 10.1159/000087476
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3213
Kanao, Hiroyuki, Enomoto, Takayuki, Kimura, Toshihiro, Fujita, Masami, Nakashima, Ryuichi, Ueda, Yutaka, Ueno, Yuko, Miyatake, Takashi, Yoshizaki, Tatsuo, Buzard, Gregory S, Tanigami, Akira, Yoshino, Kiyoshi, Murata, Yuji
Overexpression of LAMP3/TSC403/DC-LAMP promotes metastasis in uterine cervical cancer.
Cancer Res
2005
65:8640-5
PubMed ID: 16204031
DOI: 10.1158/0008-5472.CAN-04-4112
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9048
Shiro Okumura, Hiroyuki Saitoh, Tomoyuki Ishikawa, Naoya Wasano, Satoko Yamashita, Ken-Ichi Kusumoto, Tetsuyuki Akao, Eiichi Mizuki, Michio Ohba, Kuniyo Inouye
Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines
J Agric Food Chem
2005
53 (16), 6313-8
PubMed ID: 16076112
DOI: 10.1021/jf0506129
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2894
Ito, Akio, Sasaguri, Yasuyuki, Kitada, Sakae, Kusaka, Yoshitomo, Kuwano, Kyoko, Masutomi, Kenjiro, Mizuki, Eiichi, Akao, Tetsuyuki, Ohba, Michio
A Bacillus thuringiensis crystal protein with selective cytocidal action to human cells.
J Biol Chem
2004
279:21282-6
PubMed ID: 15026424
DOI: 10.1074/jbc.M401881200
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15604
Suganuma T, Ino K, Shibata K, Nomura S, Kajiyama H, Kikkawa F, Tsuruoka N, Mizutani S.
Regulation of aminopeptidase A expression in cervical carcinoma: role of tumor-stromal interaction and vascular endothelial growth factor
Lab Invest
2004
84(5):639-48
PubMed ID: 15048132
DOI: 10.1038/labinvest.3700072
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