Cell No. : Cell Name
RCB0638 : TCS
update : 2022/07/07
|
| Comment | Human cell line derived from uterine cervix cancer. Keratinizing squamous carcinoma. Said producing CEA. |
| Comment from the depositor | |
| Terms and conditions | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
| Remarks | |
| Order Form |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
|
|
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
|
|
|
Basic information
|
Depositor |
Izumi, Rikuichi
|
| Originator |
Izumi, Rikuichi & Kawabata, Masakiyo
|
| Year of deposit |
1991
|
| Another name |
TC-S
|
| Animal |
_human
< Mammals
|
| Genus |
Homo
|
| Species |
sapiens
|
| Race |
Japanese
|
| Gender |
Female
|
| Age at sampling |
78 years
|
| Tissue |
cervix, lymph node meta
|
| Disease name |
large cell, keratinizing
|
| Metastatic ability |
Yes
|
| Metastatic tissue |
lymph node
|
| Classification |
cancer
|
| Year of origin |
1982
|
| Memo_1 |
Mycoplasma was eliminated with MC-210 by the depositor.
|
|
Lifespan |
infinite
|
| Morphology |
epithelial-like
|
| Cellosaurus(Expasy) |
CVCL_8160
|
|
| |
deposit info |
lot info |
|
Medium |
Medium List |
|
Culture type |
|
Adherent cells
|
| Culture medium |
|
MEM + 10% FBS
|
| Antibiotics |
|
Free
|
|
Passage method |
|
0.25% Trypsin
|
Culture information
|
Passage ratio |
|
1 : 8 split
|
| SC frequency |
|
Subculture : once/week, Medium Renewal : 2 times/week
|
| Temperature |
|
37
℃
|
| CO2 concentration |
|
5
%
|
| Freeze medium |
|
Medium + 10% DMSO
|
| Freezing method |
|
Slow freezing
|
| Mycoplasma/Acholeplasma |
|
(-)
|
| Virus (HIV) |
|
(-)
|
| Isozyme |
|
LD, NP
|
| Chromosome mode |
|
89-180(50) : /83(2),84(3),85(5),86(5),87(5),88(3)/
|
| STR(human) |
|
OK
|
| Reference information |
Reference |
1
|
| User's Publication |
12
|
| User's Publication |
|
21167
Lin X, Yoshikawa N, Liu W, Matsukawa T, Nakamura K, Yoshihara M, Koya Y, Sugiyama M, Tamauchi S, Ikeda Y, Yokoi A, Shimizu Y, Kajiyama H.
DDIT4 Facilitates Lymph Node Metastasis via the Activation of NF-κB Pathway and Epithelial-Mesenchymal Transition.
Reprod Sci
2023
PubMed ID: 37016173
DOI: 10.1007/s43032-023-01230-y
|
|
7659
Murata T, Mizushima H, Chinen I, Moribe H, Yagi S, Hoffman RM, Kimura T, Yoshino K, Ueda Y, Enomoto T, Mekada E.
HB-EGF and PDGF mediate reciprocal interactions of carcinoma cells with cancer-associated fibroblasts to support progression of uterine cervical cancers.
Cancer Res.
2011
71:6633-42
PubMed ID: 22009535
DOI: 10.1158/0008-5472.CAN-11-0034
|
|
6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
DOI: 10.1111/j.1749-0774.2009.00071.x
|
|
18316
Yeasmin S, Nakayama K, Ishibashi M, Katagiri A, Iida K, Purwana IN, Nakayama N, Miyazaki K.
Expression of the bric-a-brac tramtrack broad complex protein NAC-1 in cervical carcinomas seems to correlate with poorer prognosis
Clin Cancer Res
2008
14(6):1686-91
PubMed ID: 18347169
DOI: 10.1158/1078-0432.CCR-07-4085
|
|
9059
Y-C Jung, E Mizuki, T Akao, J-C Côté
Isolation and Characterization of a Novel Bacillus Thuringiensis Strain Expressing a Novel Crystal Protein With Cytocidal Activity Against Human Cancer Cells
J Appl Microbiol
2007
103 (1), 65-79
PubMed ID: 17584453
DOI: 10.1111/j.1365-2672.2006.03260.x
|
|
3335
Yoshino K, Iimura E, Saijo K, Iwase S, Fukami K, Ohno T, Obata Y, Nakamura Y.
Essential role for gene profiling analysis in the authentication of human cell lines.
Hum Cell
2006
19(1):43-8
PubMed ID: 16643607
DOI: 10.1111/j.1749-0774.2005.00007.x
|
|
3413
Yamashita, Satoko, Katayama, Hideki, Saitoh, Hiroyuki, Akao, Tetsuyuki, Park, Yu Shin, Mizuki, Eiichi, Ohba, Michio, Ito, Akio
Typical Three-Domain Cry Proteins of Bacillus thuringiensis Strain A1462 Exhibit Cytocidal Activity on Limited Human Cancer Cells.
J Biochem
2005
138:663-72
PubMed ID: 16428294
DOI: 10.1093/jb/mvi177
|
|
18118
Terauchi M, Kajiyama H, Shibata K, Ino K, Mizutani S, Kikkawa F.
Anti-progressive effect of neutral endopeptidase 24.11 (NEP/CD10) on cervical carcinoma in vitro and in vivo
Oncology
2005
;69(1):52-62
PubMed ID: 16103735
DOI: 10.1159/000087476
|
|
3213
Kanao, Hiroyuki, Enomoto, Takayuki, Kimura, Toshihiro, Fujita, Masami, Nakashima, Ryuichi, Ueda, Yutaka, Ueno, Yuko, Miyatake, Takashi, Yoshizaki, Tatsuo, Buzard, Gregory S, Tanigami, Akira, Yoshino, Kiyoshi, Murata, Yuji
Overexpression of LAMP3/TSC403/DC-LAMP promotes metastasis in uterine cervical cancer.
Cancer Res
2005
65:8640-5
PubMed ID: 16204031
DOI: 10.1158/0008-5472.CAN-04-4112
|
|
9048
Shiro Okumura, Hiroyuki Saitoh, Tomoyuki Ishikawa, Naoya Wasano, Satoko Yamashita, Ken-Ichi Kusumoto, Tetsuyuki Akao, Eiichi Mizuki, Michio Ohba, Kuniyo Inouye
Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines
J Agric Food Chem
2005
53 (16), 6313-8
PubMed ID: 16076112
DOI: 10.1021/jf0506129
|
|
2894
Ito, Akio, Sasaguri, Yasuyuki, Kitada, Sakae, Kusaka, Yoshitomo, Kuwano, Kyoko, Masutomi, Kenjiro, Mizuki, Eiichi, Akao, Tetsuyuki, Ohba, Michio
A Bacillus thuringiensis crystal protein with selective cytocidal action to human cells.
J Biol Chem
2004
279:21282-6
PubMed ID: 15026424
DOI: 10.1074/jbc.M401881200
|
|
15604
Suganuma T, Ino K, Shibata K, Nomura S, Kajiyama H, Kikkawa F, Tsuruoka N, Mizutani S.
Regulation of aminopeptidase A expression in cervical carcinoma: role of tumor-stromal interaction and vascular endothelial growth factor
Lab Invest
2004
84(5):639-48
PubMed ID: 15048132
DOI: 10.1038/labinvest.3700072
|
Back
Top
CELL BANK Website