Cell No. : Cell Name
RCB0637 : CTLL-2
update : 2020/09/24
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| Comment | Cytotoxic T-cell line. IL-2 dependent. |
| Comment from the depositor | |
| Terms and conditions | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, a prior written permission of the DEPOSITOR or the RIKEN BRC is necessary. |
| Remarks | |
| Order Form |
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
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Basic information
|
Depositor |
Todokoro, Kazuo
|
| Originator |
Smith, K. A.
|
| Year of deposit |
1991
|
| Animal |
mouse
< Mammals
|
| Tissue |
T cell
|
| Classification |
transformed
|
|
Lifespan |
infinite
|
| Morphology |
lymphocyte-like
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| |
deposit info |
lot info |
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Medium |
Medium List |
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Culture type |
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Suspension cells
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| Medium and additives |
|
RPMI1640 + 10% FBS + 50-100U/ml mouse IL-2
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| Antibiotics |
|
Free
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|
Passage method |
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dilution
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Culture information
|
Passage ratio |
|
1 : 10 split
|
| SC frequency |
|
Subculture : 2 times/week
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| Temperature |
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37
℃
|
| CO2 concentration |
|
5
%
|
| Freeze medium |
|
Medium + 10% DMSO
|
| Freezing method |
|
Slow freezing
|
| Mycoplasma |
|
(-)
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| SSLP(mouse) |
|
OK
|
| Isozyme |
|
LD, NP
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| Images |
deposit info | lot info |
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| Reference information |
Reference |
5
|
| User's Publication |
11
|
| Reference |
|
2614
Fernandez-Botran R, Sanders, V M, Mosmann, T R, Vitetta, E S
Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells.
J Exp Med
1988
168:543-58
PubMed ID: 2970518
|
|
4784
Gillis S, Scheid M, Watson J.
Biochemical and biologic characterization of lymphocyte regulatory molecules. III. The isolation and phenotypic characterization of Interleukin-2 producing T cell lymphomas.
J Immunol
1980
125(6):2570-8
PubMed ID: 6968790
|
|
4785
Mochizuki D, Watson J, Gillis S.
Biochemical and biologic characterization of lymphocyte regulatory molecules. IV. Purification of Interleukin 2 from a murine T cell lymphoma.
J Immunol
1980
125(6):2579-83
PubMed ID: 7000903
|
|
2613
Gillis S, Smith, K A
In vitro generation of tumor-specific cytotoxic lymphocytes. Secondary allogeneic mixed tumor lymphocyte culture of normal murine spleen cells.
J Exp Med
1977
146:468-82
PubMed ID: 69003
|
|
1370
Gillis S, Smith, K A
Long term culture of tumour-specific cytotoxic T cells.
Nature
1977
268:154-6
PubMed ID: 145543
|
| User's Publication |
|
7294
Asama T, Arima TH, Gomi T, Keishi T, Tani H, Kimura Y, Tatefuji T, Hashimoto K.
Lactobacillus kunkeei YB38 from honeybee products enhances IgA production in healthy adults.
J. Appl. Microbiol.
2015
119:818-26
PubMed ID: 26121394
|
|
5334
Mimoto F, Katada H, Kadono S, Igawa T, Kuramochi T, Muraoka M, Wada Y, Haraya K, Miyazaki T, Hattori K.
Engineered antibody Fc variant with selectively enhanced FcγRIIb binding over both FcγRIIa(R131) and FcγRIIa(H131).
Protein Eng Des Sel
2013
26(10):589-98
PubMed ID: 23744091
|
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8048
Kobayashi N, Saito T, Uematsu T, Kishi K, Toba M, Kohda N, Suzuki T.
Oral administration of heat-killed Lactobacillus pentosus strain b240 augments protection against influenza virus infection in mice.
Int. Immunopharmacol.
2011
11:199-203
PubMed ID: 21095259
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|
2705
Kushida S, Peng, B G, Uchimura E, Kuang M, Huang L, Miwa M, Ohno T
A tumour vaccine of fixed tumour fragments in a controlled-release vehicle with cytokines for therapy of hepatoma in mice.
Dig Liver Dis
2004
36:478-85
PubMed ID: 15285528
|
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2765
Shou, Zhangfei, Yamada, Kazuya, Kawata, Hiroko, Yokoyama, Osamu, Miyamoto, Kaoru
A mechanism of induction of the mouse zinc-fingers and homeoboxes 1 (ZHX1) gene expression by interleukin-2.
Biochem Biophys Res Commun
2004
314:885-90
PubMed ID: 14741719
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2474
Fukushima K, Yamashita K
Interleukin-2 carbohydrate recognition modulates CTLL-2 cell proliferation.
J Biol Chem
2001
276:7351-6
PubMed ID: 11076950
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2560
Ito A, Kataoka, T R, Kim, D K, Koma Y, Lee, Y M, Kitamura Y
Inhibitory effect on natural killer activity of microphthalmia transcription factor encoded by the mutant mi allele of mice.
Blood
2001
97:2075-83
PubMed ID: 11264174
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5333
Fukushima K, Hara-Kuge S, Ideo H, Yamashita K.
Carbohydrate recognition site of interleukin-2 in relation to cell proliferation.
J Biol Chem
2001
276(33):31202-8
PubMed ID: 11390392
|
|
11035
T Matsuguchi, K Takagi, T Musikacharoen, Y Yoshikai
Gene expressions of lipopolysaccharide receptors, toll-like receptors 2 and 4, are differently regulated in mouse T lymphocytes
Blood
2000
95(4):1378-85.
PubMed ID: 10666214
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7040
Yu F, Itoyama Y, Kira J, Fujihara K, Kobayashi T, Kitamoto T, Suzumura A, Yamamoto N, Nakajima Y, Goto I.
TNF-beta produced by human T lymphotropic virus type I-infected cells influences the proliferation of human endothelial cells and fibroblasts.
J Immunol
1994
152(12):5930-8
PubMed ID: 8207218
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1773
Xu, B., Aoyama, K. and Ueda, A.
In Vitro Evaluation of Contact Sensitivity to DNCB Using Hapten-Stimulatied In Vitro Interleukin-2 Production by Murine Lymph Node Cells
Toxicology Methods
1993
3:183-194
|
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