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4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signalling pathway.
J Cell Mol Med
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Int J Biol Macromol
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Feng X, Lu J, Wu Y, Xu H.
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J Physiol Sci
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Rong Li, Zijing Guan, Shuyan Bi, Fanhua Wang, Liang He, Xin Niu, Yu You, Yuwei Liu, Yi Ding, Stefan Siwko, Ning Wang, Ziming Zhang, Yunyun Jin, Jian Luo
The proton-activated G protein-coupled receptor GPR4 regulates the development of osteoarthritis via modulating CXCL12/CXCR7 signaling
Cell Death Dis
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Single Application of Low-Dose, Hydroxyapatite-Bound BMP-2 or GDF-5 Induces Long-Term Bone Formation and Biomechanical Stabilization of a Bone Defect in a Senile Sheep Lumbar Osteopenia Model
Biomedicines
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Cell Discov
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Lab Invest
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Nat Commun
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Biotechnol Bioeng
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Biomed Pharmacother
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Bone
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Synthetic poly(2-acrylamido-2-methylpropanesulfonic acid) gel induces chondrogenic differentiation of ATDC5 cells via a novel protein reservoir function.
J Biomed Mater Res A
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J Bone Miner Res
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J Cell Physiol
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J Orthop Res
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Lubricin Contributes to Homeostasis of Articular Cartilage by Modulating Differentiation of Superficial Zone Cells
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Biochem Biophys Res Commun
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J Biol Chem
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ANGPTL2 Promotes Inflammation via Integrin α5β1 in Chondrocytes
Cartilage
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J Pathol
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Nature Aging
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Biomedicines
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Zhu M, Xu Q, Yang X, Zhan H, Zhang B, Liu X, Dai M.
Vindoline Attenuates Osteoarthritis Progression Through Suppressing the NF-κB and ERK Pathways in Both Chondrocytes and Subchondral Osteoclasts
Front Pharmacol
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Biomaterials
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Exp Mol Pathol
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Inflammation
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Sci Rep
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J Biomed Mater Res A
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Colloids Surf B Biointerfaces
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Biochem Biophys Res Commun
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PLoS One
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EMBO Mol Med
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Paraspeckle protein p54nrb links Sox9-mediated transcription with RNA processing during chondrogenesis in mice.
J Clin Invest
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Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9.
J Biol Chem
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Int J Biol Macromol
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Am J Physiol Endocrinol Metab
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Ann Rheum Dis
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Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation.
J Biol Chem
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Dev Dyn
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Glucosamine regulates differentiation of a chondrogenic cell line, ATDC5.
Biol Pharm Bull
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The MR tracking of transplanted ATDC5 cells using fluorinated poly-L-lysine-CF3.
Biomaterials
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J Periodontal Res
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Biochim Biophys Acta
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Nuclear factor E2 p45-related factor 2 negatively regulates chondrogenesis.
Bone
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Trps1 regulates proliferation and apoptosis of chondrocytes through Stat3 signaling.
Dev Biol
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J Orthop Res
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Exp Cell Res
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Mol Cell Endocrinol
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Am J Physiol Endocrinol Metab
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J Bone Joint Surg Br
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J Bone Miner Metab
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Excess magnesium inhibits excess calcium-induced matrix-mineralization and production of matrix gla protein (MGP) by ATDC5 cells.
Biochem Biophys Res Commun
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Calcif Tissue Int
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J Biol Chem
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Milk growth factor (MGF) induces transformation into ATDC5 cells, prechondrocytes, and cooperates with retinoic acid to transform the cells into new forms.
Life Sci
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Iron ions derived from the nitric oxide donor sodium nitroprusside inhibit mineralization.
Eur J Pharmacol
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Elevated expression of hypoxia inducible factor-2alpha in terminally differentiating growth plate chondrocytes.
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Mol Cell Endocrinol
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Tissue Eng
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TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.
Arthritis Res Ther
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J Endocrinol
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Ceramide inhibition of chondrocyte proliferation and bone growth is IGF-I independent.
J Endocrinol
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J Biosci Bioeng
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Yano F, Kugimiya F, Ohba S, Ikeda T, Chikuda H, Ogasawara T, Ogata N, Takato T, Nakamura K, Kawaguchi H, Chung UI
The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.
Biochem Biophys Res Commun
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Expression of GABA(A) and GABA(B) receptors in rat growth plate chondrocytes: activation of the GABA receptors promotes proliferation of mouse chondrogenic ATDC5 cells.
Mol. Cell. Biochem.
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Functional expression of particular isoforms of excitatory amino acid transporters by rodent cartilage.
Biochem. Pharmacol.
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Takumi Tamayama, Kentaro Maemura, Kiyoto Kanbara,Hana Hayasaki, Yasuaki Yabumoto, Masayoshi Yuasa,and Masahito Watanabe
Expression of GABAAand GABABreceptorsin rat growth plate chondrocytes: Activationof the GABA receptors promotes proliferationof mouse chondrogenic ATDC5 cells
Molecular and Cellular Biochemistry
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Effects of retinoic acid on the differentiation of chondrogenic progenitor cells, ATDC5.
J Med Dent Sci
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Quantitative transcriptional profiling of ATDC5 mouse progenitor cells during chondrogenesis.
Differentiation
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Interleukin-1beta induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner.
Biochem J
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A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese.
Hum Mol Genet
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Inhibition of Cdk6 expression through p38 MAP kinase is involved in differentiation of mouse prechondrocyte ATDC5.
J Cell Physiol
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Laminin-5 suppresses chondrogenic differentiation of murine teratocarcinoma cell line ATDC5.
Exp Cell Res
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Phenytoin stimulates chondrogenic differentiation in mouse clonal chondrogenic EC cells, ATDC5.
J Toxicol Sci
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GPI-specific phospholipase D (GPI-PLD) is expressed during mouse development and is localized to the extracellular matrix of the developing mouse skeleton.
Bone
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Matrix Biol
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Lectins induce resistance to proteases and/or mechanical stimulus in all examined cells--including bone marrow mesenchymal stem cells--on various scaffolds.
Exp Cell Res
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295:119-27
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Fujita, Takashi, Azuma, Yasutaka, Fukuyama, Ryo, Hattori, Yuji, Yoshida, Carolina, Koida, Masao, Ogita, Kiyokazu, Komori, Toshihisa
Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling.
J Cell Biol
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WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair.
Am J Pathol
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p21(Cip-1/SDI-1/WAF-1) expression via the mitogen-activated protein kinase signaling pathway in insulin-induced chondrogenic differentiation of ATDC5 cells.
Biochem. Biophys. Res. Commun.
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Nat. Struct. Mol. Biol.
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Dexamethasone inhibits insulin-induced chondrogenesis of ATDC5 cells by preventing PI3K-Akt signaling and DNA binding of Runx2.
J Cell Biochem
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Oligonucleotide decoy mimicking alphaA-crystallin-binding protein 1 binding site on mouse Col2a1 enhancer stimulates transcription from the adjacent Col2a1 promoter in chondrogenic ATDC5 cell.
Mol Biotechnol
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Madhavi Ayyalasomayajula , Sydha Salihu , Vincent Kish , Nilay Mukherjee
Influence of Rearrangement of Actin Cytoskeleton on the Overall Material Properties of ATDC5 Cells During Chondrogenesis
ASME 2004 International Mechanical Engineering Congress and Exposition
2004
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Binnerts ME, Wen X, Canté-Barrett K, Bright J, Chen HT, Asundi V, Sattari P, Tang T, Boyle B, Funk W, Rupp F.
Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins.
Biochem Biophys Res Commun
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Evaluation of different conditions for ligating dumbbell-shaped oligonucleotides.
Mol Biotechnol
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Jayendran Srinivasan , Vincent Kish , Sydha Salihu , Madhavi Ayyalasomayajula , Nilay Mukherjee
Poking Cells in Cell-Gel Constructs: A Potential Way of Measuring Fluid Pressure in Cells
ASME 2004 International Mechanical Engineering Congress and Exposition
2004
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Jayendran Srinivasan, Vincent Kish, Sydha Salihu, Madhavi Ayyalasomayajula, Nilay Mukherjee
Poking Cells in Cell-Gel Constructs: A Potential Way of Measuring Fluid Pressure in Cells
Advances in Bioengineering
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Madhavi Ayyalasomayajula, Sydha Salihu, Vincent Kish, Nilay Mukherjee
Influence of Rearrangement of Actin Cytoskeleton on the Overall Material Properties of ATDC5 Cells During Chondrogenesis
Advances in Bioengineering
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Exp Cell Res
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PTHrP rescues ATDC5 cells from apoptosis induced by FGF receptor 3 mutation.
J Bone Miner Res
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BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression.
J Biol Chem
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Suppression of differentiation and proliferation of early chondrogenic cells by Notch.
J Bone Miner Metab
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Cis-acting intronic elements that regulate cartilage-specific alternative splicing of the type II collagen (Col2) pre-mRNA lie at or near splice site junction sequences flanking exon 2 of the gene.
J Bone Miner Res
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18(9):1716-22
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A new approach to an artificial joint based on bio-cartilage/porous β-tricalcium phosphate system
Journal of the European Ceramic Society
2003
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Koshizuka Y, Yamada T, Hoshi K, Ogasawara T, Chung UI, Kawano H, Nakamura Y, Nakamura K, Ikegawa S, Kawaguchi H.
Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
J Biol Chem
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