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Cell No. : Cell Name
RCB0555 : GCIY  update : 2022/11/17
CommentStomach cancer (Borrmann IV). Mucin, CA19-9, CEA, alphafetoprotein positive.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Nozue, Mutsumi
Originator Nozue, Mutsumi
Year of deposit 1990
Original cell TKG0405
Animal human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Female
Tissue stomach
Disease name adenocarcinoma (Borrmann IV)
Metastastatic ability Yes
Classification cancer
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_1228
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives MEM + 15% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : once/1-2 weeks, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Virus (HIV) (-)
Isozyme LD, NP
Chromosome mode 56-122(50) : /59(4),60(11),61(19),62(3),63(2),66(1)/
STR(human) OK
Images
deposit info
lot info
Reference information Reference 3
User's Publication 67


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Reference
4757  Nozue M, Nishida M, Todoroki T, Fukao K, Tanaka M.  Selection of three out of 24 anti-cancer agents in poorly-differentiated gastric cancer cell lines, evaluated by the AUC/delta IC50 ratio.  Anticancer Drugs  1995  6(2):291-302  PubMed ID: 7795277   DOI: 10.1097/00001813-199504000-00014
4758  Nozue M, Todoroki T, Fukao K.  5-fu dose-dependency in mtx/s-fu sequential therapy assessed by in-vitro assay using gastric-cancer cell-lines.  Oncol Rep  1995  2(5):737-40  PubMed ID: 21597807   DOI: 10.3892/or.2.5.737
1324  Nozue M, Nishida M, Todoroki T, Iwasaki Y  [Establishment and characterization of a human scirrhus type gastric cancer cell line, GCIY, producing CA19-9]  Hum Cell  1991  4:71-5  PubMed ID: 1653599  

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User's Publication
20619  Shirakihara T, Yamaguchi H, Kondo T, Yashiro M, Sakai R.  Transferrin receptor 1 promotes the fibroblast growth factor receptor-mediated oncogenic potential of diffused-type gastric cancer.  Oncogene  2022    PubMed ID: 35338344   DOI: 10.1038/s41388-022-02270-5
20642  Kasai S, Kuwayama N, Motoo Y, Kawashima A, Matsumoto K, Yano S, Matsushima K, Yasumoto K.  Dual blockade of MET and VEGFR2 signaling pathways as a potential therapeutic maneuver for peritoneal carcinomatosis in scirrhous gastric cancer.  Biochem Biophys Res Commun  2022  600:80-86  PubMed ID: 35196631   DOI: 10.1016/j.bbrc.2022.02.045
20664  Han Y, Dong Q, Liu T, Chen X, Yu C, Zhang Y.  The novel mechanism of Med12-mediated drug resistance in a TGFBR2-independent manner.  Biochem Biophys Res Commun  2022  610:1-7  PubMed ID: 35461070   DOI: 10.1016/j.bbrc.2022.04.029
20907  Sera T, Sakuma T, Maruo K, Tsujio G, Yamamoto Y, Sugimoto A, Kushiyama S, Togano S, Kuroda K, Kasashima H, Ohira M, Maeda K.  Candidate Oncogenes, ARHGAP4, NOS3, and OR51B5, for the Development of Scirrhous-type Gastric Cancer.  Anticancer Res  2022  42(11):5195-5203  PubMed ID: 36288877   DOI: 10.21873/anticanres.16026
13281  Kajioka H, Kagawa S, Ito A, Yoshimoto M, Sakamoto S, Kikuchi S, Kuroda S, Yoshida R, Umeda Y, Noma K, Tazawa H, Fujiwara T.  Targeting neutrophil extracellular traps with thrombomodulin prevents pancreatic cancer metastasis.  Cancer Lett  2021    PubMed ID: 33065249   DOI: 10.1016/j.canlet.2020.10.015
13337  Kim S, Ahn JM, Bae WJ, Han JH, Lee D.  Quantitation of ligand is critical for ligand-dependent MET signalling activation and determines MET-targeted therapeutic response in gastric cancer.  Gastric Cancer  2021  24(3):577-588  PubMed ID: 33164142   DOI: 10.1007/s10120-020-01139-4
20028  Ito A, Kagawa S, Sakamoto S, Kuwada K, Kajioka H, Yoshimoto M, Kikuchi S, Kuroda S, Yoshida R, Tazawa H, Fujiwara T.  Extracellular vesicles shed from gastric cancer mediate protumor macrophage differentiation.  BMC Cancer  2021  21(1):102  PubMed ID: 33509150   DOI: 10.1186/s12885-021-07816-6
20191  Matsumi Y, Kagawa T, Yano S, Tazawa H, Shigeyasu K, Takeda S, Ohara T, Aono H, Hoffman RM, Fujiwara T, Kishimoto H.  Hyperthermia generated by magnetic nanoparticles for effective treatment of disseminated peritoneal cancer in an orthotopic nude-mouse model.  Cell Cycle  2021  1-12  PubMed ID: 34110969   DOI: 10.1080/15384101.2021.1919441
20415  Ikari N, Serizawa A, Tanji E, Yamamoto M, Furukawa T.  Analysis of RHOA mutations and their significance in the proliferation and transcriptome of digestive tract cancer cells.  Oncol Lett  2021  22(4):735  PubMed ID: 34466148   DOI: 10.3892/ol.2021.12996
16129  Nagamura Y, Miyazaki M, Nagano Y, Tomiyama A, Ohki R, Yanagihara K, Sakai R, Yamaguchi H.  SHP2 as a Potential Therapeutic Target in Diffuse-Type Gastric Carcinoma Addicted to Receptor Tyrosine Kinase Signaling  Cancers (Basel)  2021  13(17):4309  PubMed ID: 34503119   DOI: 10.3390/cancers13174309
13504  Baatar S, Bai T, Yokobori T, Gombodorj N, Nakazawa N, Ubukata Y, Kimura A, Kogure N, Sano A, Sohda M, Sakai M, Tumenjargal A, Ogata K, Kuwano H, Shirabe K, Saeki H.  High RAD18 Expression is Associated with Disease Progression and Poor Prognosis in Patients with Gastric Cancer  Ann Surg Oncol  2020  27(11):4360-4368  PubMed ID: 32356270   DOI: 10.1245/s10434-020-08518-2
16827  Ishikawa W, Kikuchi S, Ogawa T, Tabuchi M, Tazawa H, Kuroda S, Noma K, Nishizaki M, Kagawa S, Urata Y, Fujiwara T.  Boosting Replication and Penetration of Oncolytic Adenovirus by Paclitaxel Eradicate Peritoneal Metastasis of Gastric Cancer  Mol Ther Oncolytics  2020  18:262-271  PubMed ID: 32728614   DOI: 10.1016/j.omto.2020.06.021
11505  Kageyama-Yahara N, Yamamichi N, Takahashi Y, Takeuchi C, Matsumoto Y, Sakaguchi Y, Koike K.  Tandem repeats of the 5' flanking region of human MUC5AC have a role as a novel enhancer in MUC5AC gene expression.  Biochem Biophys Rep  2019  18:100632  PubMed ID: 30993217   DOI: 10.1016/j.bbrep.2019.100632
11511  Behan FM, Iorio F, Picco G, Gonçalves E, Beaver CM, Migliardi G, Santos R, Rao Y, Sassi F, Pinnelli M, Ansari R, Harper S, Jackson DA, McRae R, Pooley R, Wilkinson P, van der Meer D, Dow D, Buser-Doepner C, Bertotti A, Trusolino L, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ.  Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.  Nature  2019    PubMed ID: 30971826   DOI: 10.1038/s41586-019-1103-9
12415  Sakamoto S, Kagawa S, Kuwada K, Ito A, Kajioka H, Kakiuchi Y, Watanabe M, Kagawa T, Yoshida R, Kikuchi S, Kuroda S, Tazawa H, Fujiwara T.  Intraperitoneal cancer-immune microenvironment promotes peritoneal dissemination of gastric cancer  Oncoimmunology  2019  8(12):e1671760  PubMed ID: 31741772   DOI: 10.1080/2162402X.2019.1671760
14274  Chan EM, Shibue T, McFarland JM, Gaeta B, Ghandi M, Dumont N, Gonzalez A, McPartlan JS, Li T, Zhang Y, Bin Liu J, Lazaro JB, Gu P, Piett CG, Apffel A, Ali SO, Deasy R, Keskula P, Ng RWS, Roberts EA, Reznichenko E, Leung L, Alimova M, Schenone M, Islam M, Maruvka YE, Liu Y, Roper J, Raghavan S, Giannakis M, Tseng YY, Nagel ZD, D'Andrea A, Root DE, Boehm JS, Getz G, Chang S, Golub TR, Tsherniak A, Vazquez F, Bass AJ.  WRN helicase is a synthetic lethal target in microsatellite unstable cancers  Nature  2019  568(7753):551-556  PubMed ID: 30971823   DOI: 10.1038/s41586-019-1102-x
10662  Miyamoto S, Nagamura Y, Nakabo A, Okabe A, Yanagihara K, Fukami K, Sakai R, Yamaguchi H.  Aberrant alternative splicing of RHOA is associated with loss of its expression and activity in diffuse-type gastric carcinoma cells.  Biochem. Biophys. Res. Commun.  2018  495:1942-1947  PubMed ID: 29247652   DOI: 10.1016/j.bbrc.2017.12.067
4049  Taichi Yoshida, Takashi Maruyama, Masatomo Miura, Masahiro Inoue, Koji Fukuda, Kazuhiro Shimazu, Daiki Taguchi, Hiroaki Kanda, Masanobu Oshima, Yoshiharu Iwabuchi, Hiroyuki Shibata  Dietary intake of pyrolyzed deketene curcumin inhibits gastric carcinogenesis  Journal of Functional Foods  2018  50:192-200    DOI: 10.1016/j.jff.2018.09.033
4188  Suzuki M, Yokobori T, Gombodorj N, Yashiro M, Turtoi A, Handa T, Ogata K, Oyama T, Shirabe K, Kuwano H.  High stromal transforming growth factor β-induced expression is a novel marker of progression and poor prognosis in gastric cancer.  J Surg Oncol  2018    PubMed ID: 30260476   DOI: 10.1002/jso.25217
4380  Yoshioka T, Shien K, Namba K, Torigoe H, Sato H, Tomida S, Yamamoto H, Asano H, Soh J, Tsukuda K, Nagasaka T, Fujiwara T, Toyooka S.  Antitumor activity of pan-HER inhibitors in HER2-positive gastric cancer.  Cancer Sci.  2018  109(4):1166-1176  PubMed ID: 29465762   DOI: 10.1111/cas.13546
10277  Masuda T, Song W, Nakanishi H, Lei W, Noor AM, Arai F.  Rare cell isolation and recovery on open-channel microfluidic chip.  PLoS ONE  2017  12:e0174937  PubMed ID: 28426707   DOI: 10.1371/journal.pone.0174937
9594  Shibahara-Sone H, Gomi A, Iino T, Kano M, Nonaka C, Watanabe O, Miyazaki K, Ohkusa T.  Living cells of probiotic Bifidobacterium bifidum YIT 10347 detected on gastric mucosa in humans.  Benef Microbes  2016  7:319-26  PubMed ID: 26925600   DOI: 10.3920/BM2015.0138
9928  Diaz-Lagares A, Crujeiras AB, Lopez-Serra P, Soler M, Setien F, Goyal A, Sandoval J, Hashimoto Y, Martinez-Cardús A, Gomez A, Heyn H, Moutinho C, Espada J, Vidal A, Paúles M, Galán M, Sala N, Akiyama Y, Martínez-Iniesta M, Farré L, Villanueva A, Gross M, Diederichs S, Guil S, Esteller M.  Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer.  Proc. Natl. Acad. Sci. U.S.A.  2016  113:E7535-E7544  PubMed ID: 27821766   DOI: 10.1073/pnas.1608585113
3733  Nishikawaji T, Akiyama Y, Shimada S, Kojima K, Kawano T, Eishi Y, Yuasa Y, Tanaka S.  Oncogenic roles of the SETDB2 histone methyltransferase in gastric cancer.  Oncotarget  2016  7(41):67251-67265  PubMed ID: 27572307   DOI: 10.18632/oncotarget.11625
5811  Maejima R et al  Enhanced expression of semaphorin 3E is involved in the gastric cancer development.  Int J Oncol  2016  49(3):887-94  PubMed ID: 27572291   DOI: 10.3892/ijo.2016.3593
5812  Hirashita Y et al  Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells.  Cancer Sci  2016  107(12):1919-1928  PubMed ID: 27699948   DOI: 10.1111/cas.13094
12639  Yamashita K, Kuno A, Matsuda A, Ikehata Y, Katada N, Hirabayashi J, Narimatsu H, Watanabe M.  Lectin microarray technology identifies specific lectins related to lymph node metastasis of advanced gastric cancer  Gastric Cancer  2016  19(2):531-54  PubMed ID: 25840959   DOI: 10.1007/s10120-015-0491-2
7357  Yamamoto S, Fei J, Okochi M, Shimizu K, Yusa A, Kondo N, Iwata H, Nakanishi H, Honda H.  Efficient capturing of circulating tumor cells using a magnetic capture column and a size-selective filter.  Bioprocess Biosyst Eng  2015  38:1693-704  PubMed ID: 25964183   DOI: 10.1007/s00449-015-1412-9
14977  Suenaga M, Yamada S, Fuchs BC, Fujii T, Kanda M, Tanaka C, Kobayashi D, Fujiwara M, Tanabe KK, Kodera Y.  CD44 single nucleotide polymorphism and isoform switching may predict gastric cancer recurrence  J Surg Oncol  2015  112(6):622-8  PubMed ID: 26416034   DOI: 10.1002/jso.24056
15000  Sakamoto A, Akiyama Y, Shimada S, Zhu WG, Yuasa Y, Tanaka S.  DNA Methylation in the Exon 1 Region and Complex Regulation of Twist1 Expression in Gastric Cancer Cells  PLoS One  2015  10(12):e0145630  PubMed ID: 26695186   DOI: 10.1371/journal.pone.0145630
15183  Toda K, Nagasaka T, Umeda Y, Tanaka T, Kawai T, Fuji T, Taniguchi F, Yasui K, Kubota N, Takehara Y, Tazawa H, Kagawa S, Sun DS, Nishida N, Goel A, Fujiwara T.  Genetic and epigenetic alterations of netrin-1 receptors in gastric cancer with chromosomal instability  Clin Epigenetics  2015  7(1):73  PubMed ID: 26207151   DOI: 10.1186/s13148-015-0096-y
5825  Ito A, Ito Y, Matsushima S, Tsuchida D, Ogasawara M, Hasegawa J, Misawa K, Kondo E, Kaneda N, Nakanishi H.  New whole-body multimodality imaging of gastric cancer peritoneal metastasis combining fluorescence imaging with ICG-labeled antibody and MRI in mice.  Gastric Cancer  2014  17(3):497-507  PubMed ID: 24288123   DOI: 10.1007/s10120-013-0316-0
5302  Yamaguchi H, Takanashi M, Yoshida N, Ito Y, Kamata R, Fukami K, Yanagihara K, Sakai R.  Saracatinib impairs the peritoneal dissemination of diffuse-type gastric carcinoma cells resistant to Met and fibroblast growth factor receptor inhibitors.  Cancer Sci  2014  105(5):528-36  PubMed ID: 24612061   DOI: 10.1111/cas.12387
15817  Endo F, Nishizuka SS, Kume K, Ishida K, Katagiri H, Ishida K, Sato K, Iwaya T, Koeda K, Wakabayashi G.  A compensatory role of NF-κB to p53 in response to 5-FU-based chemotherapy for gastric cancer cell lines  PLoS One  2014  9(2):e90155  PubMed ID: 24587255   DOI: 10.1371/journal.pone.0090155
15987  Sogabe M, Nozaki H, Tanaka N, Kubota T, Kaji H, Kuno A, Togayachi A, Gotoh M, Nakanishi H, Nakanishi T, Mikami M, Suzuki N, Kiguchi K, Ikehara Y, Narimatsu H.  Novel glycobiomarker for ovarian cancer that detects clear cell carcinoma  J Proteome Res  2014  13(3):1624-35  PubMed ID: 24498956   DOI: 10.1021/pr401109n
5845  Konno-Shimizu M1, Yamamichi N, Inada K, Kageyama-Yahara N, Shiogama K, Takahashi Y, Asada-Hirayama I, Yamamichi-Nishina M, Nakayama C, Ono S, Kodashima S, Fujishiro M, Tsutsumi Y, Ichinose M, Koike K.  Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.  PLoS One  2013  8(2):e56766  PubMed ID: 23451082   DOI: 10.1371/journal.pone.0056766
5847  Zhao L, Yasumoto K, Kawashima A, Nakagawa T, Takeuchi S, Yamada T, Matsumoto K, Yonekura K, Yoshie O, Yano S.  Paracrine activation of MET promotes peritoneal carcinomatosis in scirrhous gastric cancer.  Cancer Sci  2013  104(12):1640-6  PubMed ID: 24118504   DOI: 10.1111/cas.12301
6075  Murakami H, Nakanishi H, Tanaka H, Ito S, Misawa K, Ito Y, Ikehara Y, Kondo E, Kodera Y.  Establishment and characterization of novel gastric signet-ring cell and non signet-ring cell poorly differentiated adenocarcinoma cell lines with low and high malignant potential.  Gastric Cancer  2013  16(1):74-83  PubMed ID: 22450770   DOI: 10.1007/s10120-012-0149-2
13662  Murakami H, Ito S, Tanaka H, Kondo E, Kodera Y, Nakanishi H.  Establishment of new intraperitoneal paclitaxel-resistant gastric cancer cell lines and comprehensive gene expression analysis  Anticancer Res  2013  33(10):4299-307  PubMed ID: 24122996  
5853  Nakanishi H, Ito S, Matsui M, Ito Y, Misawa K, Kodera Y.  Noninvasive and real-time fluorescence imaging of peritoneal metastasis in nude mice.  Methods Mol Biol  2012  872:85-95  PubMed ID: 22700405   DOI: 10.1007/978-1-61779-797-2_6
5856  Sato Y, Morimoto K, Kubo T, Yanagihara K, Seyama T.  High mannose-binding antiviral lectin PFL from Pseudomonas fluorescens Pf0-1 promotes cell death of gastric cancer cell MKN28 via interaction with α2-integrin.  PLoS One  2012  7(9):e45922  PubMed ID: 23029318   DOI: 10.1371/journal.pone.0045922
16307  Ooki A, Yamashita K, Kikuchi S, Sakuramoto S, Katada N, Waraya M, Kawamata H, Nishimiya H, Nakamura K, Watanabe M.  Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancer  BMC Cancer  2011  11:122  PubMed ID: 21466710   DOI: 10.1186/1471-2407-11-122
8118  Shirasawa Y, Shibahara-Sone H, Iino T, Ishikawa F.  Bifidobacterium bifidum BF-1 suppresses Helicobacter pylori-induced genes in human epithelial cells.  J. Dairy Sci.  2010  93:4526-34  PubMed ID: 20854986   DOI: 10.3168/jds.2010-3274
6410  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Is parainfluenza virus a threatening virus for human cancer cell lines?  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309   DOI: 10.1111/j.1749-0774.2009.00071.x
5893  Hara M, Nakanishi H, Jun Q, Kanemitsu Y, Ito S, Mochizuki Y, Yamamura Y, Kodera Y, Tatematsu M, Hirai T, Kato T.  Comparative analysis of intraperitoneal minimal free cancer cells between colorectal and gastric cancer patients using quantitative RT-PCR: possible reason for rare peritoneal recurrence in colorectal cancer.  Clin Exp Metastasis  2007  24(3):179-89  PubMed ID: 17487561   DOI: 10.1007/s10585-007-9067-9
5899  Yokoyama H, Ikehara Y, Kodera Y, Ikehara S, Yatabe Y, Mochizuki Y, Koike M, Fujiwara M, Nakao A, Tatematsu M, Nakanishi H.  Molecular basis for sensitivity and acquired resistance to gefitinib in HER2-overexpressing human gastric cancer cell lines derived from liver metastasis.  Br J Cancer  2006  95(11):1504-13  PubMed ID: 17088902   DOI: 10.1038/sj.bjc.6603459
5906  Imura K, Ueda Y, Hayashi T, Itoh T, Shimizu K, Tamai H, Yano Y, Naito K, Kohara J, Nakane K, Matsuura Y, Takeda A, Takeda T, Kawai K, Yamagishi H.  Induction of cytotoxic T lymphocytes against human cancer cell lines using dendritic cell-tumor cell hybrids generated by a newly developed electrofusion technique.  Int J Oncol  2006  29(3):531-9   
13874  Induction of cytotoxic T lymphocytes against human cancer cell lines using dendritic cell-tumor cell hybrids generated by a newly developed electrofusion technique  Imura K, Ueda Y, Hayashi T, Itoh T, Shimizu K, Tamai H, Yano Y, Naito K, Kohara J, Nakane K, Matsuura Y, Takeda A, Takeda T, Kawai K, Yamagishi H.  Int J Oncol  2006  29(3):531-9  PubMed ID: 16865268  
3077  Nakatsu N, Yoshida Y, Yamazaki K, Nakamura T, Dan S, Fukui Y, Yamori T  Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.  Mol Cancer Ther  2005  4:399-412  PubMed ID: 15767549   DOI: 10.1158/1535-7163.MCT-04-0234
5910  Nakanishi H, Ito S, Mochizuki Y, Tatematsu M.  Evaluation of chemosensitivity of micrometastases with green fluorescent protein gene-tagged tumor models in mice.  Methods Mol Med  2005  2005;111:351-62  PubMed ID: 15911990   DOI: 10.1385/1-59259-889-7:351
2807  Shida D, Kitayama J, Yamaguchi H, Hama K, Aoki J, Arai H, Yamashita H, Mori K, Sako A, Konishi T, Watanabe T, Sakai T, Suzuki R, Ohta H, Takuwa Y, Nagawa H  Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells.  Exp Cell Res  2004  301:168-78  PubMed ID: 15530853   DOI: 10.1016/j.yexcr.2004.08.008
5397  Mochizuki Y, Nakanishi H, Kodera Y, Ito S, Yamamura Y, Kato T, Hibi K, Akiyama S, Nakao A, Tatematsu M.  TNF-alpha promotes progression of peritoneal metastasis as demonstrated using a green fluorescence protein (GFP)-tagged human gastric cancer cell line.  Clin Exp Metastasis  2004  21(1):39-47.  PubMed ID: 15065601   DOI: 10.1023/b:clin.0000017181.01474.35
3796  Fukami T, Fukuhara H, Kuramochi M, Maruyama T, Isogai K, Sakamoto M, Takamoto S, Murakami Y.  Promoter methylation of the TSLC1 gene in advanced lung tumors and various cancer cell lines.  Int J Cancer  2003  107(1):53-9  PubMed ID: 12925956   DOI: 10.1002/ijc.11348
5931  Terashima M, Fujiwara H, Takagane A, Abe K, Irinoda T, Nakaya T, Yonezawa H, Oyama K, Saito K, Kanzaki N, Ohtani S, Nemoto T, Hoshino Y, Kogure M, Gotoh M.  Prediction of sensitivity to fluoropyrimidines by metabolic and target enzyme activities in gastric cancer.  Gastric Cancer  2003  6 Suppl 1:71-81.  PubMed ID: 12775024   DOI: 10.1007/s10120-003-0221-z
5932  Fujiwara 1, Terashima M, Irinoda T, Takagane A, Abe K, Nakaya T, Yonezawa H, Oyama K, Takahashi M, Saito K, Takechi T, Fukushima M, Shirasaka T.  Superior antitumour activity of S-1 in tumours with a high dihydropyrimidine dehydrogenase activity.  Eur J Cancer  2003  39(16):2387-94  PubMed ID: 14556932   DOI: 10.1016/s0959-8049(03)00513-6
5935  Dan S, Shirakawa M, Mukai Y, Yoshida Y, Yamazaki K, Kawaguchi T, Matsuura M, Nakamura Y, Yamori T.  Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.  Cancer Sci  2003  94(12):1074-82  PubMed ID: 14662023   DOI: 10.1111/j.1349-7006.2003.tb01403.x
5941  Fujiwara H, Terashima M, Irinoda T, Takagane A, Abe K, Kashiwaba M, Oyama K, Takahashi M, Maesawa C, Saito K, Takechi T, Fukushima M.  Quantitative measurement of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA level in gastric cancer by real-time RT-PCR.  Jpn J Cancer Res  2002  93(12):1342-50  PubMed ID: 12495474   DOI: 10.1111/j.1349-7006.2002.tb01243.x
3763  Takaishi S, Sawada M, Morita Y, Seno H, Fukuzawa H, Chiba T.  Identification of a novel alternative splicing of human FGF receptor 4: soluble-form splice variant expressed in human gastrointestinal epithelial cells.  Biochem Biophys Res Commun  2000  19;267(2):658-62  PubMed ID: 10631118   DOI: 10.1006/bbrc.1999.2010
1906  Iida S, Akiyama Y, Nakajima T, Ichikawa W, Nihei Z, Sugihara K, Yuasa Y.  Alterations and hypermethylation of the p14(ARF) gene in gastric cancer  Int J Cancer  2000  87(5):654-8  PubMed ID: 10925358   DOI: 10.1002/1097-0215(20000901)87:5<654::aid-ijc6>3.0.co;2-p
6386  Oji Y, Ogawa H, Tamaki H, Oka Y, Tsuboi A, Kim EH, Soma T, Tatekawa T, Kawakami M, Asada M, Kishimoto T, Sugiyama H.  Expression of the Wilms' tumor gene WT1 in solid tumors and its involvement in tumor cell growth.  Jpn J Cancer Res  1999  90(2):194-204  PubMed ID: 10189890   DOI: 10.1111/j.1349-7006.1999.tb00733.x
17255  Saijo Y, Hong X, Tanaka M, Tazawa R, Liu SQ, Saijo K, Ohno T, Koike K, Ohkuda K, Satoh K, Nukiwa T.  Autologous high-killing cytotoxic T lymphocytes against human lung cancer are induced using interleukin (IL)-1beta, IL-2, IL-4, and IL-6: possible involvement of dendritic cells  Clin Cancer Res  1999  5(5):1203-9  PubMed ID: 10353758  
6409  Hassan S, Kinoshita Y, Kawanami C, Kishi K, Matsushima Y, Ohashi A, Funasaka Y, Okada A, Maekawa T, He-Yao W, Chiba T.  Expression of protooncogene c-kit and its ligand stem cell factor (SCF) in gastric carcinoma cell lines.  Dig Dis Sci  1998  43(1):8-14  PubMed ID: 9508539   DOI: 10.1023/a:1018851415704
5973  Tamura G, Sakata K, Nishizuka S, Maesawa C, Suzuki Y, Iwaya T, Terashima M, Saito K, Satodate R.  Analysis of the fragile histidine triad gene in primary gastric carcinomas and gastric carcinoma cell lines.  Genes Chromosomes Cancer  1997  20(1):98-102  PubMed ID: 9290961  
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