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20187
Miki T, Nakai T, Hashimoto M, Kajiwara K, Tsutsumi H, Mihara H.
Intracellular artificial supramolecules based on de novo designed Y15 peptides.
Nat Commun
2021
12(1):3412
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20262
Yamashita J, Nishiike Y, Fleming T, Kayo D, Okubo K.
Estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka.
Commun Biol
2021
4(1):948
PubMed ID: 34373576
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16137
Takashima Y, Ishikawa K, Miyawaki R, Ogawa M, Ishii T, Misaka T, Kobayashi S.
Modulatory Effect of Theaflavins on Apical Sodium-Dependent Bile Acid Transporter (ASBT) Activity
J Agric Food Chem
2021
69(33):9585-9596
PubMed ID: 34346218
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13115
Urabe T, Yanase Y, Motoike S, Harada K, Hide I, Tanaka S, Tsutsumi YM, Kawamoto M, Sakai N.
Propofol induces the elevation of intracellular calcium via morphological changes in intracellular organelles, including the endoplasmic reticulum and mitochondria.
Eur J Pharmacol
2020
PubMed ID: 32681942
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13197
Yahiro Y, Maeda S, Morikawa M, Koinuma D, Jokoji G, Ijuin T, Komiya S, Kageyama R, Miyazono K, Taniguchi N.
BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts.
Bone Res
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PubMed ID: 32923015
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13243
Kasai K, Kuroda Y, Takabuchi Y, Nitta A, Kobayashi T, Nozaka H, Miura T, Nakamura T.
Phosphorylation of Thr328 in hyaluronan synthase 2 is essential for hyaluronan synthesis.
Biochem Biophys Res Commun
2020
PubMed ID: 32993960
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13610
Puteri MU, Watanabe Y, Wardhani BWK, Amalia R, Abdelaziz M, Kato M.
PMEPA1/TMEPAI isoforms function via its PY and Smad-interaction motifs for tumorigenic activities of breast cancer cells
Genes Cells
2020
25(6):375-390
PubMed ID: 32181976
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20269
Motoike S, Taguchi K, Harada K, Asano M, Hide I, Tanaka S, Irifune M, Sakai N.
Syntaxin 3 interacts with serotonin transporter and regulates its function.
J Pharmacol Sci
2020
145(4):297-307
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11407
Ohara-Imaizumi M, Aoyagi K, Yamauchi H, Yoshida M, Mori MX, Hida Y, Tran HN, Ohkura M, Abe M, Akimoto Y, Nakamichi Y, Nishiwaki C, Kawakami H, Hara K, Sakimura K, Nagamatsu S, Mori Y, Nakai J, Kakei M, Ohtsuka T.
ELKS/Voltage-Dependent Ca2+ Channel-β Subunit Module Regulates Polarized Ca2+ Influx in Pancreatic β Cells.
Cell Rep
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PubMed ID: 30699350
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Shimahara Y, Sugawara K, Kojo KH, Kawai H, Yoshida Y, Hasezawa S, Kutsuna N.
IMACEL: A cloud-based bioimage analysis platform for morphological analysis and image classification.
PLoS ONE
2019
PubMed ID: 30794647
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11521
Ivanova H, Wagner LE 2nd, Tanimura A, Vandermarliere E, Luyten T, Welkenhuyzen K, Alzayady KJ, Wang L, Hamada K, Mikoshiba K, De Smedt H, Martens L, Yule DI, Parys JB, Bultynck G.
Bcl-2 and IP3 compete for the ligand-binding domain of IP3Rs modulating Ca2+ signaling output.
Cell. Mol. Life Sci.
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11706
Jun Miyazaki, Yasunobu Toumon
Label-free dynamic imaging of mitochondria and lysosomes within living cells via simultaneous dual-pump photothermal microscopy
Biomedical Optics Express
2019
PubMed ID: 31799051
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11751
Shinoda H, Lu K, Nakashima R, Wazawa T, Noguchi K, Matsuda T, Nagai T.
Acid-Tolerant Reversibly Switchable Green Fluorescent Protein for Super-resolution Imaging under Acidic Conditions.
Cell Chem Biol
2019
PubMed ID: 31422907
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9468
Kazuyo Fujita, Masaharu Somiya, Shun'ichi Kuroda, Shuji Hinuma
Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes
Biochem Biophys Res Commun
2019
510(1):184-190
PubMed ID: 30678809
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9621
Kota Abe, Atsuko Shimada, Sayaka Tayama, Hotaka Nishikawa, Takuya Kaneko, Sachiko Tsuda, Akari Karaiwa, Takaaki Matsui , Tohru Ishitani, Hiroyuki Takeda
Horizontal Boundary Cells, a Special Group of Somitic Cells, Play Crucial Roles in the Formation of Dorsoventral Compartments in Teleost Somite
Cell Rep
2019
27(3):928-939.e4
PubMed ID: 30995487
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12410
Asano M, Motoike S, Yokota C, Usuki N, Yamamoto H, Urabe T, Katarao K, Hide I, Tanaka S, Kawamoto M, Irifune M, Sakai
SKF-10047, a prototype Sigma-1 receptor agonist, augmented the membrane trafficking and uptake activity of the serotonin transporter and its C-terminus-deleted mutant via a Sigma-1 receptor-independent mechanism
harmacol Sci . 2019 Jan;139(1):29-36
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PubMed ID: 30522963
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Hori T, Okuno T, Hirata K, Yamashita K, Kawano Y, Yamamoto M, Hato M, Nakamura M, Shimizu T, Yokomizo T, Miyano M, Yokoyama S.
Na+-mimicking ligands stabilize the inactive state of leukotriene B4 receptor BLT1.
Nat. Chem. Biol.
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11078
Maeda T, Suetake H, Odaka T, Miyadai T.
Original Ligand for LTβR Is LIGHT: Insight into Evolution of the LT/LTβR System.
J. Immunol.
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Kondo D, Noguchi A, Takahashi I, Kubota H, Yano T, Sato Y, Toyono M, Sawaishi Y, Takahashi T.
A novel ZC4H2 gene mutation, K209N, in Japanese siblings with arthrogryposis multiplex congenita and intellectual disability: characterization of the K209N mutation and clinical findings.
Brain Dev.
2018
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PubMed ID: 29803542
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Takasugi N, Araya R, Kamikubo Y, Kaneshiro N, Imaoka R, Jin H, Kashiyama T, Hashimoto Y, Kurosawa M, Uehara T, Nukina N, Sakurai T.
TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.
PLoS ONE
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11184
Nagae M, Kizuka Y, Mihara E, Kitago Y, Hanashima S, Ito Y, Takagi J, Taniguchi N, Yamaguchi Y.
Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V.
Nat Commun
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9(1):3380
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Miyahara T, Adachi N, Seki T, Hide I, Tanaka S, Saito N, Irifune M, Sakai N.
Propofol induced diverse and subtype-specific translocation of PKC families.
J. Pharmacol. Sci.
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Kitaoka S, Hatogai J, Ochiai W, Sugiyama K.
Zonation of the drug-metabolizing enzyme cytochrome P450 3A in infant mice begins in pre-weaning period.
J Toxicol Sci
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Fujiwara S, Matsui TS, Ohashi K, Deguchi S, Mizuno K.
Solo, a RhoA-targeting guanine nucleotide exchange factor, is critical for hemidesmosome formation and acinar development in epithelial cells.
PLoS ONE
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Kizuka Y, Nakano M, Yamaguchi Y, Nakajima K, Oka R, Sato K, Ren CT, Hsu TL, Wong CH, Taniguchi N.
An Alkynyl-Fucose Halts Hepatoma Cell Migration and Invasion by Inhibiting GDP-Fucose-Synthesizing Enzyme FX, TSTA3.
Cell Chem Biol
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Moritani C, Kawakami K, Fujita A, Kawakami K, Hatanaka T, Tsuboi S.
Anti-oxidative Activity of Hydrolysate from Rice Bran Protein in HepG2 Cells.
Biol. Pharm. Bull.
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Inoue T, Takemura M, Fushimi N, Fujimori Y, Onozato T, Kurooka T, Asari T, Takeda H, Kobayashi M, Nishibe H, Isaji M.
Mizagliflozin, a novel selective SGLT1 inhibitor, exhibits potential in the amelioration of chronic constipation.
Eur. J. Pharmacol.
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Kubota Y, Fujioka K, Takekawa M.
WGA-based lectin affinity gel electrophoresis: A novel method for the detection of O-GlcNAc-modified proteins.
PLoS ONE
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Takano T, Wu M, Nakamuta S, Naoki H, Ishizawa N, Namba T, Watanabe T, Xu C, Hamaguchi T, Yura Y, Amano M, Hahn KM, Kaibuchi K.
Discovery of long-range inhibitory signaling to ensure single axon formation.
Nat Commun
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Hirai C, Badawy SMM, Zhang L, Okada T, Kajimoto T, Nakamura S.
Phospholipase D is Dispensable for Epidermal Growth Factor-Induced Chemotaxis
Kobe J Med Sci
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10018
Niwa F, Sakuragi S, Kobayashi A, Takagi S, Oda Y, Bannai H, Mikoshiba K.
Dissection of local Ca(2+) signals inside cytosol by ER-targeted Ca(2+) indicator.
Biochem. Biophys. Res. Commun.
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Chung S, Kijima K, Kudo A, Fujisawa Y, Harada Y, Taira A, Takamatsu N, Miyamoto T, Matsuo Y, Nakamura Y.
Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor
Oncotarget
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Ohto U, Ishida H, Krayukhina E, Uchiyama S, Inoue N, Shimizu T.
Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature
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Higashio H, Satoh Y, Saino T.
Mast cell degranulation is negatively regulated by the Munc13-4-binding small-guanosine triphosphatase Rab37
Sci Rep
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Tatani K, Hiratochi M, Kikuchi N, Kuramochi Y, Watanabe S, Yamauchi Y, Itoh F, Isaji M, Shuto S.
Identification of Adenine and Benzimidazole Nucleosides as Potent Human Concentrative Nucleoside Transporter 2 Inhibitors: Potential Treatment for Hyperuricemia and Gout
J Med Chem
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Aimi T, Suzuki K, Hoshino T, Mizushima T.
Dextran sulfate sodium inhibits amyloid-β oligomer binding to cellular prion protein.
J. Neurochem.
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Arai Y, Yamamoto T, Minamikawa T, Takamatsu T, Nagai T.
Spectral fingerprinting of individual cells visualized by cavity-reflection-enhanced light-absorption microscopy.
PLoS ONE
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Sumida M, Hane M, Yabe U, Shimoda Y, Pearce OM, Kiso M, Miyagi T, Sawada M, Varki A, Kitajima K, Sato C.
Rapid Trimming of Cell Surface Polysialic Acid (PolySia) by Exovesicular Sialidase Triggers Release of Preexisting Surface Neurotrophin.
J. Biol. Chem.
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Michiko Yoshida, Kenji Hata, Rikako Takashima, Koichiro Ono, Eriko Nakamura, Yoshifumi Takahata, Tomohiko Murakami, Sachiko Iseki, Teruko Takano-Yamamoto, Riko Nishimura, Toshiyuki Yoneda
The Transcription Factor Foxc1 Is Necessary for Ihh-Gli2-regulated Endochondral Ossification
Nat Commun
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6:6653
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Tsukada C, Saito T, Maekawa M, Mano N, Oda A, Hirasawa N, Hiratsuka M.
Functional characterization of 12 allelic variants of CYP2C8 by assessment of paclitaxel 6α-hydroxylation and amodiaquine N-deethylation
Drug Metab Pharmacokinet
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30(5):366-73
PubMed ID: 26427316
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10473
Ohsawa Y, Takayama K, Nishimatsu S, Okada T, Fujino M, Fukai Y, Murakami T, Hagiwara H, Itoh F, Tsuchida K, Hayashi Y, Sunada Y.
The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy
PLoS One
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PubMed ID: 26226340
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7579
Suzuki-Nakagawa C, Nishimura M, Tsukamoto T, Aoyama S, Ebihara A, Suzuki F, Nakagawa T.
Participation of the extracellular domain in (pro)renin receptor dimerization.
Biochem. Biophys. Res. Commun.
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Yamagishi N, Nakao R, Kondo R, Nishitsuji M, Saito Y, Kuga T, Hatayama T, Nakayama Y.
ncreased expression of sorcin is associated with multidrug resistance in leukemia cells via up-regulation of MDR1 expression through cAMP response element-binding protein
Biochem Biophys Res Commun
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448(4):430-6
PubMed ID: 24796664
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14397
Takeda A, Tsubaki T, Sagae N, Onda Y, Inada Y, Mochizuki T, Okumura K, Kikuyama S, Kobayashi T, Iwamuro S.
Bacterial toxin-inducible gene expression of cathelicidin-B1 in the chicken bursal lymphoma-derived cell line DT40: functional characterization of cathelicidin-B1
Peptides
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15874
Takaoka M, Saito H, Takenaka K, Miki Y, Nakanishi A.
BRCA2 phosphorylated by PLK1 moves to the midbody to regulate cytokinesis mediated by nonmuscle myosin IIC
Cancer Res
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15943
Tsuyoshi KIMURA, Yukie KANDA, Asami SANO, Kwangwoo NAM, Yoshihiro SASAKI, Kazunari AKIYOSHI, Toshiya FUJISATO, Akio KISHIDA
High Hydrostatic Pressurized Lipoplex Enhances Transfection Efficiency In Vitro
Advanced Biomedical Engineering
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15956
Nishimoto T, Kashiwagi K, Saito N, Shirai Y.
Both C1B domain and pseudosubstrate region are necessary for saturated fatty acid-induced translocation of εPKC to the plasma membrane: distinct role of intramolecular domains for different translocation
Biochem Biophys Res Commun
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432(2):384-8
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7728
Kimura S, Nakagawa T, Matsuo Y, Ishida Y, Okamoto Y, Hayashi M.
JTT-305, an orally active calcium-sensing receptor antagonist, stimulates transient parathyroid hormone release and bone formation in ovariectomized rats.
Eur. J. Pharmacol.
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7746
Kimura T, Nibe Y, Funamoto S, Okada M, Furuzono T, Ono T, Yoshizawa H, Fujisato T, Nam K, Kishida A.
Preparation of a Nanoscaled Poly(vinyl alcohol)/Hydroxyapatite/DNA Complex Using High Hydrostatic Pressure Technology for In Vitro and In Vivo Gene Delivery.
J Drug Deliv
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Chimura T, Launey T, Ito M.
Evolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif.
BMC Genomics
2011
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7912
Amano K, Hata K, Muramatsu S, Wakabayashi M, Takigawa Y, Ono K, Nakanishi M, Takashima R, Kogo M, Matsuda A, Nishimura R, Yoneda T.
Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription.
Mol. Biol. Cell
2011
22:1300-11
PubMed ID: 21346191
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7917
Shirai Y, Morioka S, Sakuma M, Yoshino K, Otsuji C, Sakai N, Kashiwagi K, Chida K, Shirakawa R, Horiuchi H, Nishigori C, Ueyama T, Saito N.
Direct binding of RalA to PKCη and its crucial role in morphological change during keratinocyte differentiation.
Mol. Biol. Cell
2011
22:1340-52
PubMed ID: 21346190
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9481
Takahide Matsui, Takashi Itoh, Mitsunori Fukuda
Small GTPase Rab12 Regulates Constitutive Degradation of Transferrin Receptor
Trafficc
2011
12(10):1432-43
PubMed ID: 21718402
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15351
Terao Y, Ayaori M, Ogura M, Yakushiji E, Uto-Kondo H, Hisada T, Ozasa H, Takiguchi S, Nakaya K, Sasaki M, Komatsu T, Iizuka M, Horii S, Mochizuki S, Yoshimura M, Ikewaki K.
Effect of sulfonylurea agents on reverse cholesterol transport in vitro and vivo
J Atheroscler Thromb
2011
18(6):513-30
PubMed ID: 21636950
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16163
Yamamoto M, Iguchi G, Takeno R, Okimura Y, Sano T, Takahashi M, Nishizawa H, Handayaningshi AE, Fukuoka H, Tobita M, Saitoh T, Tojo K, Mokubo A, Morinobu A, Iida K, Kaji H, Seino S, Chihara K, Takahashi Y.
Adult combined GH, prolactin, and TSH deficiency associated with circulating PIT-1 antibody in humans
J Clin Invest
2011
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8336
Haraguchi S, Koyama T, Hasunuma I, Vaudry H, Tsutsui K.
Prolactin increases the synthesis of 7alpha-hydroxypregnenolone, a key factor for induction of locomotor activity, in breeding male Newts.
Endocrinology
2010
151:2211-22
PubMed ID: 20219980
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8373
Hakozaki A, Yoda M, Tohmonda T, Furukawa M, Hikata T, Uchikawa S, Takaishi H, Matsumoto M, Chiba K, Horiuchi K, Toyama Y.
Receptor activator of NF-kappaB (RANK) ligand induces ectodomain shedding of RANK in murine RAW264.7 macrophages.
J. Immunol.
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Toyohira Y, Ueno S, Tsutsui M, Itoh H, Sakai N, Saito N, Takahashi K, Yanagihara N.
Stimulatory effects of the soy phytoestrogen genistein on noradrenaline transporter and serotonin transporter activity.
Mol Nutr Food Res
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Gushima M, Kawate H, Ohnaka K, Nomura M, Takayanagi R.
Raloxifene induces nucleolar translocation of the estrogen receptor.
Mol. Cell. Endocrinol.
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Takigawa Y, Hata K, Muramatsu S, Amano K, Ono K, Wakabayashi M, Matsuda A, Takada K, Nishimura R, Yoneda T.
The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9.
J Cell Sci
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Kwang-Il Kim, Jae-Woo Lee, Yoshihiro Ito, Jeong-Hwa Kang, Kwang-Sup Song, Eui-Chan Jang, Tae-Il Son
Preparation of photo-reactive azidophenyl chitosan derivative for immobilization of growth factors
Journal of Applied Polymer Science
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Sogawa C, Mitsuhata C, Kumagai-Morioka K, Sogawa N, Ohyama K, Morita K, Kozai K, Dohi T, Kitayama S.
Expression and function of variants of human catecholamine transporters lacking the fifth transmembrane region encoded by exon 6
PLoS One
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15692
Yoshikawa F, Banno Y, Otani Y, Yamaguchi Y, Nagakura-Takagi Y, Morita N, Sato Y, Saruta C, Nishibe H, Sadakata T, Shinoda Y, Hayashi K, Mishima Y, Baba H, Furuichi T.
Phospholipase D family member 4, a transmembrane glycoprotein with no phospholipase D activity, expression in spleen and early postnatal microglia
PLoS One
2010
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Sakurai-Yageta M, Masuda M, Tsuboi Y, Ito A, Murakami Y.
Tumor suppressor CADM1 is involved in epithelial cell structure.
Biochem. Biophys. Res. Commun.
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Adachi E, Kazoe Y, Sato Y, Suzuki Y, Urano T, Ueyama T, Saito N, Nikolaev VO, Lohse MJ, Tominaga M, Mogami H.
A technique for monitoring multiple signals with a combination of prism-based total internal reflection fluorescence microscopy and epifluorescence microscopy.
Pflugers Arch.
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Munekata K, Sakamoto K.
Forkhead transcription factor Foxo1 is essential for adipocyte differentiation.
In Vitro Cell. Dev. Biol. Anim.
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Yoshikawa N, Nagasaki M, Sano M, Tokudome S, Ueno K, Shimizu N, Imoto S, Miyano S, Suematsu M, Fukuda K, Morimoto C, Tanaka H.
Ligand-based gene expression profiling reveals novel roles of glucocorticoid receptor in cardiac metabolism.
Am. J. Physiol. Endocrinol. Metab.
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Tanimura A, Morita T, Nezu A, Shitara A, Hashimoto N, Tojyo Y.
Use of Fluorescence Resonance Energy Transfer-based Biosensors for the Quantitative Analysis of Inositol 1,4,5-Trisphosphate Dynamics in Calcium Oscillations.
J. Biol. Chem.
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Kawaai K, Hisatsune C, Kuroda Y, Mizutani A, Tashiro T, Mikoshiba K.
80K-H interacts with inositol 1,4,5-trisphosphate (IP3) receptors and regulates IP3-induced calcium release activity.
J. Biol. Chem.
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Murakami M, Kawachi H, Ogawa K, Nishino Y, Funaba M.
Receptor expression modulates the specificity of transforming growth factor-beta signaling pathways.
Genes Cells
2009
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Shiohara M, Shigemura T, Suzuki T, Tanaka M, Morii E, Ohtsu H, Shibahara S, Koike K.
MITF-CM, a newly identified isoform of microphthalmia-associated transcription factor, is expressed in cultured mast cells.
Int J Lab Hematol
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Shimotori M, Maruyama H, Nakamura G, Suyama T, Sakamoto F, Itoh M, Miyabayashi S, Ohnishi T, Sakai N, Wataya-Kaneda M, Kubota M, Takahashi T, Mori T, Tamura K, Kageyama S, Shio N, Maeba T, Yahagi H, Tanaka M, Oka M, Sugiyama H, Sugawara T, Mori N, Tsukamoto H, Tamagaki K, Tanda S, Suzuki Y, Shinonaga C, Miyazaki J, Ishii S, Gejyo F.
Novel mutations of the GLA gene in Japanese patients with Fabry disease and their functional characterization by active site specific chaperone.
Hum. Mutat.
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Satoh T, Arii J, Suenaga T, Wang J, Kogure A, Uehori J, Arase N, Shiratori I, Tanaka S, Kawaguchi Y, Spear PG, Lanier LL, Arase H.
PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B.
Cell
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Characterization of peroxisomal targeting signals on alanine: glyoxylate aminotransferase.
Biol Pharm Bull
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Koyama T, Iwamuro S.
Molecular cloning of a cDNA encoding atypical antimicrobial and cytotoxic Brevinin-1Ja from the skin of the Japanese brown frog, Rana japonica.
Zoolog Sci
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Tsuji T, Kondo E, Yasoda A, Inamoto M, Kiyosu C, Nakao K, Kunieda T.
Hypomorphic mutation in mouse Nppc gene causes retarded bone growth due to impaired endochondral ossification.
Biochem Biophys Res Commun
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Granulogenesis in non-neuroendocrine COS-7 cells induced by EGFP-tagged chromogranin A gene transfection: identical and distinct distribution of CgA and EGFP.
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A novel alternative splicing isoform of human T-cell leukemia virus type 1 bZIP factor (HBZ-SI) targets distinct subnuclear localization.
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A CCAAT/enhancer binding protein beta isoform, liver-enriched inhibitory protein, regulates commitment of osteoblasts and adipocytes.
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Aggrecanase-1 (ADAMTS-4) interacts with alpha1-antitrypsin
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Impaired nuclear translocation, nuclear matrix targeting, and intranuclear mobility of mutant androgen receptors carrying amino acid substitutions in the deoxyribonucleic acid-binding domain derived from androgen insensitivity syndrome patients.
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A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis.
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A loss-of-function mutation in natriuretic peptide receptor 2 (Npr2) gene is responsible for disproportionate dwarfism in cn/cn mouse.
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Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines
J Agric Food Chem
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Lectins induce resistance to proteases and/or mechanical stimulus in all examined cells--including bone marrow mesenchymal stem cells--on various scaffolds.
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PubMed ID: 22353356
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15297
Arakawa T, Ohta T, Abiko Y, Okayama M, Mizoguchi I, Takuma T.
A polymerase chain reaction-based method for constructing a linear vector with site-specific DNA methylation
Anal Biochem
2011
416(2):211-7
PubMed ID: 21669180
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