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細胞番号 : 細胞名
RCB0535 : RAW 264  update : 2021/04/02
細胞特性(Comment:英)Mouse leukemic monocyte. Abelson leukemia virus induced. Since “Terms and conditions” etc. for this cell line can be changed, the users of this cell line must refer to ECA85062803 prior to order. Application consideration(PDF 580KB)
細胞特性(日)Abelson leukemia virusで転換したマクロファージ様細胞。 ECACC由来株。使用条件等がECACCによって随時変更となる可能性があります。ご購入前に、ECA85062803 を必ずご参照ください。 培養開始にあたっての注意(PDF 580KB)をご参照ください。
使用条件(英)1) There is no restriction regarding use for basic researches. However, since “Terms and conditions” etc. for this cell line can be changed, the users of this cell line must refer to ECA85062803 prior to order. 2) In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
使用条件(日)1) 基礎的研究につきましては、使用制限はありません。しかし、使用条件等がECACCによって随時変更となる可能性があるので、購入前に、ECA85062803 を必ず参照すること。2) 商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。
提供申込書類(英) Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず(cellbank.brc@riken.jp)までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 ECACC
寄託日 1990
動物種 _mouse < Mammals
動物系統名 BALB/c
採取組織 leukemic monocyte
細胞分類 transformed
入手歴 overseas, ECACC
細胞寿命 infinite
細胞形態 other
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 MEM + 10% FBS + 0.1mM NEAA
抗生物質 Free
継代方法 0.25% trypsin + 0.02% EDTA
継代密度 1 : 8 split
継代・培地交換頻度 Subculture : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
マウス系統検査 OK
文献情報 Reference(英) 1件
Reference(日) 0件
利用者成果(英) 402件
利用者成果(日) 1件

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13272  Tanaka KI, Kubota M, Shimoda M, Hayase T, Miyaguchi M, Kobayashi N, Ikeda M, Ishima Y, Kawahara M.  Thioredoxin-albumin fusion protein prevents urban aerosol-induced lung injury via suppressing oxidative stress-related neutrophil extracellular trap formation.  Environ Pollut  2021    PubMed ID: 33065363
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20088  Nurrahmah QI, Madhyastha R, Madhyastha H, Purbasari B, Maruyama M, Nakajima Y.  Retinoic acid abrogates LPS-induced inflammatory response via negative regulation of NF-kappa B/miR-21 signaling.  Immunopharmacol Immunotoxicol  2021  1-10  PubMed ID: 33757404
13434  Frederick Ayertey, Ebenezer Ofori-Attah, Stephen Antwi, Michael Amoa-Bosompem, Georgina Djameh, Nathaniel Lartey Lartey, Mistuko Ohashi, Kwadwo Asamoah Kusi, Alfred Ampomah Appiah, Regina Appiah-Opong, Laud Kenneth Okine  Anti-inflammatory activity and mechanism of action of ethanolic leaf extract of Morinda lucida Benth  Journal of Traditional and Complementary Medicine  2020/1/1   
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6906  Shinjyo N, Nakayama H, Ishimaru K, Hikosaka K, Mi-Ichi F, Norose K, Yoshida H.  Hypericum erectum alcoholic extract inhibits Toxoplasma growth and Entamoeba encystation: an exploratory study on the anti-protozoan potential.  J Nat Med  2020  74(1):294-305  PubMed ID: 31728823
11900  Fujihara Y, Abe T, Asawa Y, Nishizawa S, Saijo H, Hikita A, Hoshi K.  Influence of Damage-Associated Molecular Patterns from Chondrocytes in Tissue-Engineered Cartilage.  Tissue Eng Part A  2020    PubMed ID: 31724485
12001  Yoshimoto Y, Jo JI, Tabata Y.  Preparation of antibody-immobilized gelatin nanospheres incorporating a molecular beacon to visualize the biological function of macrophages.  Regen Ther  2020    PubMed ID: 31970268
12006  Kohara Y, Haraguchi R, Kitazawa R, Kitazawa S.  Knockdown of Lrp1 in RAW264 cells inhibits osteoclast differentiation and osteoclast-osteoblast interactions in vitro.  Biochem. Biophys. Res. Commun.  2020    PubMed ID: 31964526
12009  Bandow K, Hasegawa H, Tomomura M, Tomomura A.  Caldecrin inhibits lipopolysaccharide-induced pro-inflammatory cytokines and M1 macrophage polarization through the immunoreceptor triggering receptor expressed in myeloid cells-2.  Biochem. Biophys. Res. Commun.  2020    PubMed ID: 31973822
12016  Kawakubo M, Tanaka M, Ochi K, Watanabe A, Saka-Tanaka M, Kanamori Y, Yoshioka N, Yamashita S, Goto M, Itoh M, Shirakawa I, Kanai S, Suzuki H, Sawada M, Ito A, Ishigami M, Fujishiro M, Arima H, Ogawa Y, Suganami T.  Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects.  Sci Rep  2020    PubMed ID: 31969650
12026  Tanaka M, Miyake H, Oka S, Maeda S, Iwasaki K, Mukai T.  Effects of charged lipids on the physicochemical and biological properties of lipid-styrene maleic acid copolymer discoidal particles.  Biochim Biophys Acta Biomembr  2020    PubMed ID: 32004520
12048  Funakoshi-Tago M, Nonaka Y, Tago K, Takeda M, Ishihara Y, Sakai A, Matsutaka M, Kobata K, Tamura H.  Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2.  Sci Rep  2020    PubMed ID: 32054966
12058  Phan TKT, Shahbazzadeh F, Kihara T.  Alpha-mangostin reduces mechanical stiffness of various cells.  Hum. Cell  2020    PubMed ID: 32078151
12092  Kamiya Y, Kikuchi T, Goto H, Okabe I, Takayanagi Y, Suzuki Y, Sawada N, Okabe T, Suzuki Y, Kondo S, Hayashi JI, Mitani A.  IL-35 and RANKL Synergistically Induce Osteoclastogenesis in RAW264 Mouse Monocytic Cells.  Int J Mol Sci  2020    PubMed ID: 32197293
12110  Uchikawa M, Kato M, Nagata A, Sanada S, Yoshikawa Y, Tsunematsu Y, Sato M, Suzuki T, Hashidume T, Watanabe K, Yoshikawa Y, Miyoshi N.  Elevated levels of proinflammatory volatile metabolites in feces of high fat diet fed KK-Ay mice.  Sci Rep  2020    PubMed ID: 32231228
12126  Amlabu WE, Antwi CA, Awandare G, Gwira TM.  Elucidating the possible mechanism of action of some pathogen box compounds against Leishmania donovani.  PLoS Negl Trop Dis  2020    PubMed ID: 32275665
12130  Sanada S, Suzuki T, Nagata A, Hashidume T, Yoshikawa Y, Miyoshi N.  Intestinal microbial metabolite stercobilin involvement in the chronic inflammation of ob/ob mice.  Sci Rep  2020    PubMed ID: 32296105
12171  Kazunori Sasaki, Yuri Inami, Kenichi Tominaga, Hideo Kigoshi, Takashi Arimura , and Hiroko Isoda  Synthesis of 2-(2-Hydroxyethoxy)-3-hydroxysqualene and Characterization of Its Anti-Inflammatory Effects  BioMed Research International  2020    PubMed ID: 32382581
10948  Karen Yotsumoto, Terukazu Sanui, Urara Tanaka, Hiroaki Yamato, Rehab Alshargabi, Takanori Shinjo, Yuki Nakao, Yukari Watanabe, Chikako Hayashi, Takaharu Taketomi, Takao Fukuda, Fusanori Nishimura  Amelogenin Downregulates Interferon Gamma-Induced Major Histocompatibility Complex Class II Expression Through Suppression of Euchromatin Formation in the Class II Transactivator Promoter IV Region in Macrophages  Front Immunol  2020  11:709  PubMed ID: 32373130
12488  Takeda Y, Murata T, Jamsransuren D, Suganuma K, Kazami Y, Batkhuu J, Badral D, Ogawa H.  Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Viruses Including SARS-CoV-2  Viruses  2020  12(7):699  PubMed ID: 32605306
13012  Kumagai M, Nishikawa K, Mishima T, Yoshida I, Ide M, Watanabe A, Fujita K, Morimoto Y.  Fluorinated Kavalactone Inhibited RANKL-Induced Osteoclast Differentiation of RAW264 Cells.  Biol Pharm Bull  2020    PubMed ID: 32378565
13036  Tanaka M, Sato A, Kishimoto Y, Mabashi-Asazuma H, Kondo K, Iida K.  Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes.  Nutrients  2020    PubMed ID: 32443660
13065  Crentsil JA, Yamthe LRT, Anibea BZ, Broni E, Kwofie SK, Tetteh JKA, Osei-Safo D.  Leishmanicidal Potential of Hardwickiic Acid Isolated From Croton sylvaticus.  Front Pharmacol  2020    PubMed ID: 32523532
13097  Kim Y, Wu L, Park HC, Yang HC.  Reduction of fibrous encapsulation by polyethylene glycol-grafted liposomes containing phosphatidylserine.  Biomed Mater  2020    PubMed ID: 32615550
13137  Kawata R, Oda S, Koya Y, Kajiyama H, Yokoi T.  Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production.  Toxicology  2020    PubMed ID: 32739513
13139  Kawai K, Egami Y, Nishigaki A, Araki N.  Rab35 Targeting to the Plasma Membrane Is Dependent on the C-terminal Polybasic Cluster.  Acta Histochem Cytochem  2020    PubMed ID: 32873993
13146  Ertunc N, Sato C, Kitajima K.  Sialic acid sulfation is induced by the antibiotic treatment in mammalian cells.  Biosci Biotechnol Biochem  2020    PubMed ID: 32752946
13150  Totani H, Shinjo K, Suzuki M, Katsushima K, Mase S, Masaki A, Ito A, Ri M, Kusumoto S, Komatsu H, Ishida T, Inagaki H, Iida S, Kondo Y.  Autocrine HGF/c-Met signaling pathway confers aggressiveness in lymph node adult T-cell leukemia/lymphoma.  Oncogene  2020    PubMed ID: 32747750
13168  Mikami A, Ogita T, Namai F, Shigemori S, Sato T, Shimosato T.  Oral administration of Flavonifractor plautii attenuates inflammatory responses in obese adipose tissue.  Mol Biol Rep  2020    PubMed ID: 32808115
13180  Wada S, Kanzaki H, Katsumata Y, Yamaguchi Y, Narimiya T, Attucks OC, Nakamura Y, Tomonari H.  Bach1 Inhibition Suppresses Osteoclastogenesis via Reduction of the Signaling via Reactive Oxygen Species by Reinforced Antioxidation.  Front Cell Dev Biol  2020    PubMed ID: 32850850
13258  Takeuchi T, Horimoto Y, Oyama M, Nakatani S, Kobata K, Tamura M, Arata Y, Hatanaka T.  Osteoclast Differentiation Is Suppressed by Increased O-GlcNAcylation Due to Thiamet G Treatment.  Biol Pharm Bull  2020    PubMed ID: 32999159
13294  Nishigaki C, Nakayama M, Miyata H.  Cell physiological responses of RAW264 macrophage cells to a 50-Hz magnetic field.  Int J Radiat Biol  2020    PubMed ID: 33052723
13298  Yang X, Sasano T, Ebana Y, Takeuchi JK, Ihara K, Yamazoe M, Furukawa T.  Functional Role of the L396R Mutation of Tks5 Identified by an Exome-Wide Association Study in Atrial Fibrillation.  Circ J  2020    PubMed ID: 33087629
13324  Yahiro K, Ogura K, Goto Y, Iyoda S, Kobayashi T, Takeuchi H, Ohnishi M, Moss J.  Subtilase cytotoxin induces a novel form of Lipocalin 2, which promotes Shiga-toxigenic Escherichia coli survival.  Sci Rep  2020    PubMed ID: 33144618
13341  Matur M, Madhyastha H, Shruthi TS, Madhyastha R, Srinivas SP, Navya PN, Daima HK.  Engineering bioactive surfaces on nanoparticles and their biological interactions.  Sci Rep  2020    PubMed ID: 33184324
13373  Kuriyama T, Fukuma Y, Imashiro C, Kabayama K, Kurashina Y, Takemura K.  Detachment of RAW264.7 macrophages from a culture dish using ultrasound excited by a Langevin transducer.  J Biosci Bioeng  2020    PubMed ID: 33250410
13464  Sugiyama T, Hobro AJ, Pavillon N, Umakoshi T, Verma P, Smith N.  Label-free Raman mapping of saturated and unsaturated fatty acid uptake, storage, and return toward baseline levels in macrophages  Analyst  2020  Dec 21  PubMed ID: 33346264
13492  Masanori HASHIMOTO, Haruaki KITAGAWA, Yusuke TAKAHASHI, Mikako HAYASHI, Satoshi IMAZATO  Cytotoxicity of S-PRG Fillers: Direct Exposure of Fillers and Eluates from the Fillers to RAW264 Cells  Nano Biomedicine  2020  12:3-10 
13545  Quan H, Kim Y, Wu L, Park HC, Yang HC.  Modulation of Macrophage Polarization by Phospholipids on the Surface of Titanium  Molecules  2020  25(11):2700  PubMed ID: 32532146
13614  Kuramoto M, Kawashima N, Tazawa K, Nara K, Fujii M, Noda S, Hashimoto K, Nozaki K, Okiji T.  Mineral trioxide aggregate suppresses pro-inflammatory cytokine expression via the calcineurin/nuclear factor of activated T cells/early growth response 2 pathway in lipopolysaccharide-stimulated macrophages  Int Endod J  2020  53(12):1653-1665  PubMed ID: 32767860
13633  Lu DZ, Dong W, Feng XJ, Chen H, Liu JJ, Wang H, Zang LY, Qi MC.  CaMKII(δ) regulates osteoclastogenesis through ERK, JNK, and p38 MAPKs and CREB signalling pathway  Mol Cell Endocrinol  2020  508:110791  PubMed ID: 32173349
13639  Nishiguchi A, Taguchi T.  Development of an immunosuppressive camouflage-coating platform with nanocellulose and cell membrane vesicles  J Biomater Sci Polym Ed  2020  31(15):1912-1924  PubMed ID: 32538290
13643  Nishiguchi A, Taguchi T.  Sustained-immunostimulatory nanocellulose scaffold to enhance vaccine efficacy  J Biomed Mater Res A  2020  108(5):1159-1170  PubMed ID: 31990447
11167  Chaweewannakorn W, Ariyoshi W, Okinaga T, Fujita Y, Maki K, Nishihara T.  Ameloblastin attenuates RANKL-mediated osteoclastogenesis by suppressing activation of nuclear factor of activated T-cell cytoplasmic 1 (NFATc1).  J. Cell. Physiol.  2019  234(2):1745-175  PubMed ID: 30105896
11173  Madhyastha R, Madhyastha H, Pengjam Y, Nurrahmah QI, Nakajima Y, Maruyama M.  The pivotal role of microRNA-21 in osteoclastogenesis inhibition by anthracycline glycoside aloin.  J Nat Med  2019  73(1):59-66  PubMed ID: 30116953
11279  Sun S, Li K, Xiao L, Lei Z, Zhang Z.  Characterization of polysaccharide from Helicteres angustifolia L. and its immunomodulatory activities on macrophages RAW264.7.  Biomed. Pharmacother.  2019    PubMed ID: 30396084
11335  Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Ando K, Tanimoto K.  The effect of mesenchymal stem cells on osteoclast precursor cell differentiation.  J Oral Sci  2019    PubMed ID: 30541990
11361  Islam Z, Inui T, Ishibashi O.  Gpr137b is an orphan G-protein-coupled receptor associated with M2 macrophage polarization.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 30595385
11380  Nemoto R, Fujieda K, Hiruta Y, Hishida M, Ayano E, Maitani Y, Nagase K, Kanazawa H.  Liposomes with temperature-responsive reversible surface properties.  Colloids Surf B Biointerfaces  2019    PubMed ID: 30641302
11396  Yoshinaga N, Uchida S, Naito M, Osada K, Cabral H, Kataoka K.  Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection.  Biomaterials  2019    PubMed ID: 30669016
11383  Manabe Y, Hirata T, Sugawara T.  Inhibitory Effect of Carotenoids on Ligand-induced Lipid Raft Translocation of Immunoreceptors.  J Oleo Sci  2019    PubMed ID: 30651415
11389  Wang W, Nakashima KI, Hirai T, Inoue M.  Anti-inflammatory effects of naturally occurring retinoid X receptor agonists isolated from Sophora tonkinensis Gagnep. via retinoid X receptor/liver X receptor heterodimers.  J Nat Med  2019    PubMed ID: 30656541
11457  Takahashi S, Yoshida M, Watanabe MM, Isoda H.  Anti-Inflammatory Effects of Aurantiochytrium limacinum 4W-1b Ethanol Extract on Murine Macrophage RAW264 Cells.  Biomed Res Int  2019    PubMed ID: 30809537
11437  Yanagihara Y, Inoue K, Saeki N, Sawada Y, Yoshida S, Lee J, Iimura T, Imai Y.  Zscan10 suppresses osteoclast differentiation by regulating expression of Haptoglobin.  Bone  2019    PubMed ID: 30771488
11454  Antwi CA, Amisigo CM, Adjimani JP, Gwira TM.  In vitro activity and mode of action of phenolic compounds on Leishmania donovani.  PLoS Negl Trop Dis  2019    PubMed ID: 30802252
11477  Zhang T, Ono K, Tsutsuki H, Ihara H, Islam W, Akaike T, Sawa T.  Enhanced Cellular Polysulfides Negatively Regulate TLR4 Signaling and Mitigate Lethal Endotoxin Shock.  Cell Chem Biol  2019    PubMed ID: 30853417
5357  Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.  AUTACs: Cargo-Specific Degraders Using Selective Autophagy.  Mol Cell  2019  76(5):797-810  PubMed ID: 31606272
11498  Narita Y, Shimizu K, Ikemoto K, Uchino R, Kosugi M, Maess MB, Magata Y, Oku N, Ogawa M.  Macrophage-targeted, enzyme-triggered fluorescence switch-on system for detection of embolism-vulnerable atherosclerotic plaques.  J Control Release  2019    PubMed ID: 30936020
11508  Saito H, Tanaka T, Sugahara M, Tanaka S, Fukui K, Wakashima T, Nangaku M.  Inhibition of prolyl hydroxylase domain (PHD) by JTZ-951 reduces obesity-related diseases in the liver, white adipose tissue, and kidney in mice with a high-fat diet.  Lab. Invest.  2019    PubMed ID: 30952940
11539  Suzuka H, Mimura A, Inaoka Y, Murase K.  Magnetic Nanoparticles in Macrophages and Cancer Cells Exhibit Different Signal Behavior on Magnetic Particle Imaging.  J Nanosci Nanotechnol  2019    PubMed ID: 31039837
11604  Miyazaki Y, Iwaihara Y, Bak J, Nakano H, Takeuchi S, Takeuchi H, Matsui T, Tachikawa D.  The cooperative induction of macrophage activation by fucoidan derived from Cladosiphon okamuranus and β-glucan derived from Saccharomyces cerevisiae.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 31221482
11608  Tsuhako R, Yoshida H, Sugita C, Kurokawa M.  Naringenin suppresses neutrophil infiltration into adipose tissue in high-fat diet-induced obese mice.  J Nat Med  2019    PubMed ID: 31218550
11617  Takeuchi T, Koinuma S, Yokosawa H, Arata Y.  An Approach for the Identification of Proteins Modified with ISG15.  Methods Mol. Biol.  2019    PubMed ID: 31256383
11704  Miori Tanaka, Ayako Sugama, Kanako Sumi, Kozue Shimizu, Yoshimi Kishimoto, Kazuo Kondo, Kaoruko Iida  Gallic acid regulates adipocyte hypertrophy and suppresses inflammatory gene expression induced by the paracrine interaction between adipocytes and macrophages in vitro and in vivo  Nutrition Research  2019  73:58-66  PubMed ID: 31841748
11736  Wang X, Batubara I, Yamauchi K, Mitsunaga T.  Identification and structure-activity relationship (SAR) of chemical constituents from Daemonorops draco (Willd.) Blume and selected commercial flavonoids on anti-osteoclastogenesis activity.  Fitoterapia  2019    PubMed ID: 31376421
11757  Manabe Y, Takii Y, Sugawara T.  Siphonaxanthin, a carotenoid from green algae, suppresses advanced glycation end product-induced inflammatory responses.  J Nat Med  2019    PubMed ID: 31432315
11772  Okuda-Hanafusa C, Uchio R, Fuwa A, Kawasaki K, Muroyama K, Yamamoto Y, Murosaki S.  Turmeronol A and turmeronol B from Curcuma longa prevent inflammatory mediator production by lipopolysaccharide-stimulated RAW264.7 macrophages, partially via reduced NF-κB signaling.  Food Funct  2019    PubMed ID: 31454011
11780  Tan H, Zhao C, Zhu Q, Katakura Y, Tanaka H, Ohnuki K, Shimizu K.  Ursolic Acid Isolated from the Leaves of Loquat ( Eriobotrya japonica) Inhibited Osteoclast Differentiation through Targeting Exportin 5.  J. Agric. Food Chem.  2019    PubMed ID: 30827108
11793  Mizuno Y, Taguchi T.  Growth factor-free, angiogenic hydrogel based on hydrophobically modified Alaska pollock gelatin.  J Tissue Eng Regen Med  2019    PubMed ID: 31503405
11801  Ueta M, Takaoka K, Yamamura M, Maeda H, Tamaoka J, Nakano Y, Noguchi K, Kishimoto H.  Effects of TGF‑β1 on the migration and morphology of RAW264.7 cells in vitro.  Mol Med Rep  2019    PubMed ID: 31545488
11810  Ara T, Koide M, Kitamura H, Sogawa N.  Effects of shokyo (Zingiberis Rhizoma) and kankyo (Zingiberis Processum Rhizoma) on prostaglandin E2 production in lipopolysaccharide-treated mouse macrophage RAW264.7 cells.  PeerJ  2019    PubMed ID: 31576251
11873  Ju N, Shimamura M, Hayashi H, Ikeda Y, Yoshida S, Nakamura A, Morishita R, Rakugi H, Nakagami H.  Preventative effects of the partial RANKL peptide MHP1-AcN in a mouse model of imiquimod-induced psoriasis.  Sci Rep  2019    PubMed ID: 31659208
6944  Yo S, Hamamura K, Mishima Y, Hamajima K, Mori H, Furukawa K, Kondo H, Tanaka K, Sato T, Miyazawa K, Goto S, Togari A.  Deficiency of GD3 Synthase in Mice Resulting in the Attenuation of Bone Loss with Aging.  Int J Mol Sci  2019  20(11):2825  PubMed ID: 31185614
9468  Kazuyo Fujita, Masaharu Somiya, Shun'ichi Kuroda, Shuji Hinuma  Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes  Biochem Biophys Res Commun  2019  510(1):184-190  PubMed ID: 30678809
10512  Sayumi Yamada et al  Anti-Inflammatory and Antimicrobial Activities of Aqueous Extracts of Wild Mushrooms from Japan  International Journal of Medicinal Mushrooms  2019  21:469-486 
10763  Ahmed Elkhateeb, Mona El-Shabrawy, Rehab F. Abdel-Rahman, Mona M. Marzouk, Ahmed H. El-Desoky, El-Sayed S. Abdel-Hameed & Sameh R. Hussein   LC-MS-based metabolomic profiling of Lepidium coronopus water extract, anti-inflammatory and analgesic activities, and chemosystematic significance  Medicinal Chemistry Research  2019  28:505–514 
10848  X.YangaZ.Lei, Y.YuaL.Xiao, D.Cheng, Z.Zhang  Phytochemical characteristics of callus suspension culture of Helicteres angustifolia L. and its in vitro antioxidant, antidiabetic and immunomodulatory activities  South African Journal of Botany  2019  121:178-185 
11886  Ali MFZ, Ohta T, Ido A, Miura C, Miura T.  The Dipterose of Black Soldier Fly (Hermetia illucens) Induces Innate Immune Response through Toll-Like Receptor Pathway in Mouse Macrophage RAW264.7 Cells.  Biomolecules  2019    PubMed ID: 31683715
11908  Pavillon N, Smith NI.  Immune cell type, cell activation, and single cell heterogeneity revealed by label-free optical methods.  Sci Rep  2019    PubMed ID: 31745140
11914  Shimakura H, Gen-Nagata F, Haritani M, Furusaki K, Kato Y, Yamashita-Kawanishi N, LE DT, Tsuzuki M, Tohya Y, Kyuwa S, Saito H, Horimoto T, Onodera T, Haga T.  Inactivation of human norovirus and its surrogate by the disinfectant consisting of calcium hydrogen carbonate mesoscopic crystals.  FEMS Microbiol. Lett.  2019    PubMed ID: 31758686
11948  Yamashiro T, Yasujima T, Ohta K, Inoue K, Yuasa H.  Identification of the amino acid residue responsible for the myricetin sensitivity of human proton-coupled folate transporter.  Sci Rep  2019    PubMed ID: 31792273
12316  Kitazawa R, Kinto-Shibahara S, Haraguchi R, Kohara Y, Kitazawa S.  Activation of protein kinase C accelerates murine osteoclastogenesis partly via transactivation of RANK gene through functional AP-1 responsive element in RANK gene promoter  Biochem Biophys Res Commun  2019  515(2):268-274  PubMed ID: 31146918
12336  Sakakura A, Pauze M, Namiki A, Funakoshi-Tago M, Tamura H, Hanaya K, Higashibayashi S, Sugai T.  Chemoenzymatic synthesis of hydroxytyrosol monoesters and their suppression effect on nitric oxide production stimulated by lipopolysaccharides  Biosci Biotechnol Biochem  2019  83(2):185-191  PubMed ID: 30319060
12555  Islam Z, Horikawa A, Inui T, Ishibashi O.  Datasets of microarray analysis to identify Gpr137b-dependent interleukin-4-responsive genes in the mouse macrophage cell line RAW264  Data Brief  2019  23:103669  PubMed ID: 31372377
12556  Saiki P, Kawano Y, Nakajima Y, Van Griensven LJLD, Miyazaki K.  Reporters Derived from RAW 264.7 for Anti-Inflammation Screening of Natural Products  Int J Mol Sci   2019  20(18):4620  PubMed ID: 31540402
12557  Kono Y, Gogatsubo S, Ohba T, Fujita T.  Enhanced macrophage delivery to the colon using magnetic lipoplexes with a magnetic field  Drug Deliv  2019  26(1):935-943  PubMed ID: 31530198
12558  Pan H, Bian X, Yang S, He Y, Yang X, Liu Y.  The cell line ontology-based representation, integration and analysis of cell lines used in China  BMC Bioinformatics  2019  20(Suppl 5):179  PubMed ID: 31272367
12559  Li F, Kitajima S, Kohno S, Yoshida A, Tange S, Sasaki S, Okada N, Nishimoto Y, Muranaka H, Nagatani N, Suzuki M, Masuda S, Thai TC, Nishiuchi T, Tanaka T, Barbie DA, Mukaida N, Takahashi C.  Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion  Cancer Res  2019  79(15):3903-3915  PubMed ID: 31189648
12978  Kojima C, Narita Y, Nakajima Y, Morimoto N, Yoshikawa T, Takahashi N, Handa A, Waku T, Tanaka N.  Modulation of Cell Adhesion and Differentiation on Collagen Gels by the Addition of the Ovalbumin Secretory Signal Peptide.  ACS Biomater Sci Eng  2019    PubMed ID: 33405701
10342  Fujihara Y, Hikita A, Takato T, Hoshi K.  Roles of macrophage migration inhibitory factor in cartilage tissue engineering.  J. Cell. Physiol.  2018  233:1490-1499  PubMed ID: 28574571
10432  Tokuyama-Nakai S, Kimura H, Ishihara T, Jisaka M, Yokota K.  In Vitro Anti-inflammatory and Antioxidant Activities of 3,5,4'-Trihydroxy-6,7-Methylenedioxyflavone-O-Glycosides and Their Aglycone from Leaves of Polygonum tinctorium Lour.  Appl. Biochem. Biotechnol.  2018  184:414-431  PubMed ID: 28721651
10557  Elfeky M, Yoneshiro T, Okamatsu-Ogura Y, Kimura K.  Adiponectin suppression of late inflammatory mediator, HMGB1-induced cytokine expression in RAW264 macrophage cells.  J. Biochem.  2018  163:143-153  PubMed ID: 29048484
10569  Yamaguchi Y, Kanzaki H, Katsumata Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.  Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation.  J. Cell. Mol. Med.  2018  22:1138-1147  PubMed ID: 29063666
10614  Stockler-Pinto MB, Soulage CO, Borges NA, Cardozo LFMF, Dolenga CJ, Nakao LS, Pecoits-Filho R, Fouque D, Mafra D.  From bench to the hemodialysis clinic: protein-bound uremic toxins modulate NF-κB/Nrf2 expression.  Int Urol Nephrol  2018  50:347-354  PubMed ID: 29151180
10645  Nagahara H, Seno T, Yamamoto A, Obayashi H, Inoue T, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y.  Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.  Biochem. Biophys. Res. Commun.  2018  495:1901-1907  PubMed ID: 29225172
10696  Kumagai M, Watanabe A, Yoshida I, Mishima T, Nakamura M, Nishikawa K, Morimoto Y.  Evaluation of Aculeatin and Toddaculin Isolated from Toddalia asiatica as Anti-inflammatory Agents in LPS-Stimulated RAW264 Macrophages.  Biol. Pharm. Bull.  2018  41:132-137  PubMed ID: 29311475
10708  Kon R, Tsubota Y, Minami M, Kato S, Matsunaga Y, Kimura H, Murakami Y, Fujikawa T, Sakurai R, Tomimoto R, Machida Y, Ikarashi N, Sugiyama K.  CPT-11-Induced Delayed Diarrhea Develops via Reduced Aquaporin-3 Expression in the Colon.  Int J Mol Sci  2018  19:  PubMed ID: 29316651
10711  Egami Y, Araki N.  Transient recruitment of M-Ras GTPase to phagocytic cups in RAW264 macrophages during FcγR-mediated phagocytosis.  Microscopy (Oxf)  2018  67:68-74  PubMed ID: 29340604
10714  Tsukayama I, Toda K, Takeda Y, Mega T, Tanaka M, Kawakami Y, Takahashi Y, Kimoto M, Yamamoto K, Miki Y, Murakami M, Suzuki-Yamamoto T.  Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway.  J Clin Biochem Nutr  2018  62:139-147  PubMed ID: 29610553
10782  Miyashita T, Minami K, Ito M, Koizumi R, Sagane Y, Watanabe T, Niwa K.  Emu Oil Reduces LPS-Induced Production of Nitric Oxide and TNF-α but not Phagocytosis in RAW 264 Macrophages.  J Oleo Sci  2018  67:471-477  PubMed ID: 29526880
10790  El-Desoky AH, Abdel-Rahman RF, Ahmed OK, El-Beltagi HS, Hattori M.  Anti-inflammatory and antioxidant activities of naringin isolated from Carissa carandas L.: In vitro and in vivo evidence.  Phytomedicine  2018  42:126-134  PubMed ID: 29655678
10799  Kawai C, Yamauchi A, Kuribayashi F.  Monoclonal antibody 7D5 recognizes the R147 epitope on the gp91phox , phagocyte flavocytochrome b558 large subunit.  Microbiol. Immunol.  2018  62:269-280  PubMed ID: 29573449
11027  Miyake T, Miyake T, Sakaguchi M, Nankai H, Nakazawa T, Morishita R.  Prevention of Asthma Exacerbation in a Mouse Model by Simultaneous Inhibition of NF-kB and STAT6 Activation Using a Chimeric Decoy Strategy  Mol Ther Nucleic Acids  2018  10:159-169  PubMed ID: 29499930
11198  Ikebuchi Y, Aoki S, Honma M, Hayashi M, Sugamori Y, Khan M, Kariya Y, Kato G, Tabata Y, Penninger JM, Udagawa N, Aoki K, Suzuki H.  Coupling of bone resorption and formation by RANKL reverse signalling.  Nature  2018  561(7722):195-200  PubMed ID: 30185903
4050  Mukai Y, Yamanishi R.  Retinol but not retinoic acid can enhance the glutathione level, in a manner similar to β-carotene, in a murine cultured macrophage cell line.  Food Sci Nutr  2018    PubMed ID: 30258608
11098  Ali MFZ, Yasin IA, Ohta T, Hashizume A, Ido A, Takahashi T, Miura C, Miura T.  The silkrose of Bombyx mori effectively prevents vibriosis in penaeid prawns via the activation of innate immunity.  Sci Rep  2018  8(1):8836  PubMed ID: 29892000
11116  Tasaka T, Kuwada E, Izuchi Y, Nishigawa R, Yamada H, Unuma H, Tokunaga K, Hayakawa A, Go A, Go K, Uto Y.  Concentration-dependent Activation of Inflammatory/Anti-inflammatory Functions of Macrophages by Hydrolyzed Whey Protein.  Anticancer Res.  2018  38(7):4299-4304  PubMed ID: 29970565
11122  Sakoda M, Kaneko M, Ohta S, Qi P, Ichimura S, Yatomi Y, Ito T.  Injectable Hemostat Composed of a Polyphosphate-Conjugated Hyaluronan Hydrogel.  Biomacromolecules  2018  19(8):3280-3290  PubMed ID: 29985587
11186  Kawasaki K, Okuda-Hanafusa C, Aoyagi M, Taoka K, Yamamoto N, Muroyama K, Murosaki S, Yamamoto Y.  Inhibitory effect of the compounds from the water extract of Curcuma longa on the production of PGE2 and NO in a macrophage cell line stimulated by LPS.  Biosci. Biotechnol. Biochem.  2018  82(12):2109-2117  PubMed ID: 30146952
11200  Odkhuu E, Komatsu T, Koide N, Naiki Y, Takeuchi K, Tanaka Y, Tsolmongyn B, Jambalganiin U, Morita N, Yoshida T, Gotoh B, Yokochi T.  Sendai virus C protein limits NO production in infected RAW264.7 macrophages.  Innate Immun  2018  24(7):430-438  PubMed ID: 30189760
11074  Tsukamoto H, Takeuchi S, Kubota K, Kobayashi Y, Kozakai S, Ukai I, Shichiku A, Okubo M, Numasaki M, Kanemitsu Y, Matsumoto Y, Nochi T, Watanabe K, Aso H, Tomioka Y.  Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKK?-IRF3 axis activation.  J. Biol. Chem.  2018  293(26):10186-10201  PubMed ID: 29760187
11112  Niino T, Tago K, Yasuda D, Takahashi K, Mashino T, Tamura H, Funakoshi-Tago M.  A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis.  Biochem. Pharmacol.  2018  155:182-197  PubMed ID: 29940171
11249  Kamiya T, Tanimoto Y, Fujii N, Negishi T, Suzuki T, Hatano T, Arimoto-Kobayashi S.  2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae.  Food Chem. Toxicol.  2018    PubMed ID: 30316843
11493  Katsumata Y, Kanzaki H, Honda Y, Tanaka T, Yamaguchi Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.  Single Local Injection of Epigallocatechin Gallate-Modified Gelatin Attenuates Bone Resorption and Orthodontic Tooth Movement in Mice.  Polymers (Basel)  2018  10(12)  PubMed ID: 30961309
11349  Sugiyama Y, Hiraiwa Y, Hagiya Y, Nakajima M, Tanaka T, Ogura SI.  5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW 264.7 macrophages.  BMC Immunol.  2018    PubMed ID: 30567499
4441  Seisho Azuma, Yoshinobu Murakami, Eiko Azuma, Kimiye Baba, Masahiko Taniguchi  Anti-inflammatory effects of flavonoids in Citrus jabara fruit peels  Trends in Immunotherapy  2018  2 
4324  Quan H, Kim Y, Park HC, Yang HC.  Effects of phosphatidylserine-containing supported lipid bilayers on the polarization of macrophages.  J Biomed Mater Res A  2018    PubMed ID: 29781181
4325  Hoshi K, Yamazaki T, Yoshikawa C, Tsugawa W, Ikebukuro K, Sode K.  Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production.  Int J Nanomedicine  2018    PubMed ID: 30122920
4326  Saiki P, Nakajima Y, Van Griensven LJLD, Miyazaki K.  Real-time monitoring of IL-6 and IL-10 reporter expression for anti-inflammation activity in live RAW 264.7 cells.  Biochem. Biophys. Res. Commun.  2018    PubMed ID: 30301531
4327  Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Tanimoto K.  Dynamic imaging of the effect of mesenchymal stem cells on osteoclast precursor cell chemotaxis for bone defects in the mouse skull.  J Dent Sci  2018    PubMed ID: 30895145
4328  Sumi K, Abe T, Kunimatsu R, Oki N, Tsuka Y, Awada T, Nakajima K, Ando K, Tanimoto K.  The effect of mesenchymal stem cells on chemotaxis of osteoclast precursor cells.  J Oral Sci  2018    PubMed ID: 29925706
4329  Kajita T, Ariyoshi W, Okinaga T, Mitsugi S, Tominaga K, Nishihara T.  Mechanisms involved in enhancement of osteoclast formation by activin-A.  J. Cell. Biochem.  2018    PubMed ID: 29737562
4330  Sakamoto T, Ohashi W, Tomita K, Hattori K, Matsuda N, Hattori Y.  Anti-inflammatory properties of cilostazol: Its interruption of DNA binding activity of NF-κB from the Toll-like receptor signaling pathways.  Int. Immunopharmacol.  2018    PubMed ID: 30005227
4331  El-Beih AA, El-Desoky AH, Al-Hammady MA, Elshamy AI, Hegazy MF, Kato H, Tsukamoto S.  New inhibitors of RANKL-induced Osteoclastogenesis from the marine sponge Siphonochalina siphonella.  Fitoterapia  2018    PubMed ID: 29729401
4332  Tanaka M, Kishimoto Y, Sasaki M, Sato A, Kamiya T, Kondo K, Iida K.  Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways.  Oxid Med Cell Longev  2018    PubMed ID: 30533177
4333  Kawabata K, Baba N, Sakano T, Hamano Y, Taira S, Tamura A, Baba S, Natsume M, Ishii T, Murakami S, Ohigashi H.  Functional properties of anti-inflammatory substances from quercetin-treated Bifidobacterium adolescentis.  Biosci. Biotechnol. Biochem.  2018    PubMed ID: 29165050
4334  Fukai E, Sato H, Watanabe M, Nakae D, Totsuka Y.  Establishment of an in vivo simulating co-culture assay platform for genotoxicity of multi-walled carbon nanotubes.  Cancer Sci.  2018    PubMed ID: 29444368
4335  Hussain Z, Uyama T, Kawai K, Binte Mustafiz SS, Tsuboi K, Araki N, Ueda N.  Phosphatidylserine-stimulated production of N-acyl-phosphatidylethanolamines by Ca2+-dependent N-acyltransferase.  Biochim Biophys Acta Mol Cell Biol Lipids  2018    PubMed ID: 29447909
4336  Takahashi S, Sakamaki M, Ferdousi F, Yoshida M, Demura M, Watanabe MM, Isoda H.  Ethanol Extract of Aurantiochytrium mangrovei 18W-13a Strain Possesses Anti-inflammatory Effects on Murine Macrophage RAW264 Cells.  Front Physiol  2018    PubMed ID: 30319432
4496  Su YW, Chim SM, Zhou L, Hassanshahi M, Chung R, Fan C, Song Y, Foster BK, Prestidge CA, Peymanfar Y, Tang Q, Butler LM, Gronthos S, Chen D, Xie Y, Chen L, Zhou XF, Xu J, Xian CJ.  Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats.  Bone  2018  116:232-247  PubMed ID: 30125729
4497  Kuroda C, Ueda K, Haniu H, Ishida H, Okano S, Takizawa T, Sobajima A, Kamanaka T, Yoshida K, Okamoto M, Tsukahara T, Matsuda Y, Aoki K, Kato H, Saito N.  Different aggregation and shape characteristics of carbon materials affect biological responses in RAW264 cells.  Int J Nanomedicine  2018  13:6079-6088  PubMed ID: 30323595
4498  Momozane T, Kawamura T, Itoh Y, Sanosaka M, Sasaki T, Kanzaki R, Ose N, Funaki S, Shintani Y, Minami M, Okumura M, Takemori H.  Carnosol suppresses interleukin-6 production in mouse lungs injured by ischemia-reperfusion operation and in RAW264.7 macrophages treated with lipopolysaccharide.  Biochem. Cell Biol.  2018  96(6):769-776  PubMed ID: 29958095
4499  Choodej S, Pudhom K, Mitsunaga T.  Inhibition of TNF-α-Induced Inflammation by Sesquiterpene Lactones from Saussurea lappa and Semi-Synthetic Analogues.  Planta Med.  2018  84(5):329-335  PubMed ID: 28962049
7036  Komiya C, Tanaka M, Tsuchiya K, Shimazu N, Mori K, Furuke S, Miyachi Y, Shiba K, Yamaguchi S, Ikeda K, Ochi K, Nakabayashi K, Hata KI, Itoh M, Suganami T, Ogawa Y.  Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis.  Sci Rep  2017  7:44754  PubMed ID: 28303974
9723  Iwazaki K, Tanaka T, Hozumi Y, Okada M, Tsuchiya R, Iseki K, Topham MK, Kawamae K, Takagi M, Goto K.  DGKζ Downregulation Enhances Osteoclast Differentiation and Bone Resorption Activity Under Inflammatory Conditions.  J. Cell. Physiol.  2017  232:617-624  PubMed ID: 27312515
9944  Kanzaki H, Shinohara F, Itohiya K, Yamaguchi Y, Katsumata Y, Matsuzawa M, Fukaya S, Miyamoto Y, Wada S, Nakamura Y.  RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice.  FASEB J.  2017  31:781-792  PubMed ID: 27836987
9964  Shirasugi M, Nishioka K, Yamamoto T, Nakaya T, Kanamura N.  Normal human gingival fibroblasts undergo cytostasis and apoptosis after long-term exposure to butyric acid.  Biochem. Biophys. Res. Commun.  2017  482:1122-1128  PubMed ID: 27914813
10001  Quan H, Park HC, Kim Y, Yang HC.  Modulation of the anti-inflammatory effects of phosphatidylserine-containing liposomes by PEGylation.  J Biomed Mater Res A  2017  105:1479-1486  PubMed ID: 27998010
10074  Takano A, Fukuda T, Shinjo T, Iwashita M, Matsuzaki E, Yamamichi K, Takeshita M, Sanui T, Nishimura F.  Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation.  Metab. Clin. Exp.  2017  69:157-170  PubMed ID: 28285646
10085  Ariyoshi W, Okinaga T, Chaweewannakorn W, Akifusa S, Nisihara T.  Mechanisms involved in enhancement of matrix metalloproteinase-9 expression in macrophages by interleukin-33.  J. Cell. Physiol.  2017  232:3481-3495  PubMed ID: 28105703
10122  Taniguchi M, Ochiai A, Toyoda R, Sato T, Saitoh E, Kato T, Tanaka T.  Effects of arginine and leucine substitutions on anti-endotoxic activities and mechanisms of action of cationic and amphipathic antimicrobial octadecapeptide from rice α-amylase.  J. Pept. Sci.  2017  23:252-260  PubMed ID: 28185358
10165  Takeuchi T, Sugimoto A, Imazato N, Tamura M, Nakatani S, Kobata K, Arata Y.  Glucosamine Suppresses Osteoclast Differentiation through the Modulation of Glycosylation Including O-GlcNAcylation.  Biol. Pharm. Bull.  2017  40:352-356  PubMed ID: 28250278
10169  Zhang J, Hiromoto S, Yamazaki T, Huang H, Jia G, Li H, Yuan G.  Macrophage phagocytosis of biomedical Mg alloy degradation products prepared by electrochemical method.  Mater Sci Eng C Mater Biol Appl  2017  75:1178-1183  PubMed ID: 28415404
10190  Ichimura K, Shimizu T, Matsumoto A, Hirai S, Yokoyama E, Takeuchi H, Yahiro K, Noda M.  Nitric oxide-enhanced Shiga toxin production was regulated by Fur and RecA in enterohemorrhagic Escherichia coli O157.  Microbiologyopen  2017  6:  PubMed ID: 28294553
10215  Yamagata Y, Tomioka H, Sakamoto K, Sato K, Harada H, Ikeda T, Kayamori K.  CD163-Positive Macrophages Within the Tumor Stroma Are Associated With Lymphangiogenesis and Lymph Node Metastasis in Oral Squamous Cell Carcinoma.  J. Oral Maxillofac. Surg.  2017  75:2144-2153  PubMed ID: 28399391
10230  Hashiguchi A, Hitachi K, Zhu W, Tian J, Tsuchida K, Komatsu S.  Mung bean (Vigna radiata (L.)) coat extract modulates macrophage functions to enhance antigen presentation: A proteomic study.  J Proteomics  2017  161:26-37  PubMed ID: 28373035
10285  Fereig RM, Kuroda Y, Terkawi MA, Mahmoud ME, Nishikawa Y.  Immunization with Toxoplasma gondii peroxiredoxin 1 induces protective immunity against toxoplasmosis in mice.  PLoS ONE  2017  12:e0176324  PubMed ID: 28448521
10288  Kato T, Toyooka T, Ibuki Y, Masuda S, Watanabe M, Totsuka Y.  Effect of physicochemical character differences on the genotoxic potency of kaolin.  Genes Environ  2017  39:12  PubMed ID: 28469735
10335  Wu S, Yano S, Chen J, Hisanaga A, Sakao K, He X, He J, Hou DX.  Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-Induced Inflammation through Dual Modulation of Inflammatory and Antioxidant Mediators.  J. Agric. Food Chem.  2017  65:5133-5141  PubMed ID: 28573848
10380  Murata K, Motomura Y, Tanaka T, Kanno S, Yano T, Onimaru M, Shimoyama A, Nishio H, Sakai Y, Oh-Hora M, Hara H, Fukase K, Takada H, Masuda S, Ohga S, Yamasaki S, Hara T.  Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease.  Clin. Exp. Immunol.  2017  190:54-67  PubMed ID: 28640392
10551  Saiki P, Kawano Y, Van Griensven LJLD, Miyazaki K.  The anti-inflammatory effect of Agaricus brasiliensis is partly due to its linoleic acid content.  Food Funct  2017  8:4150-4158  PubMed ID: 29022634
10704  Hanagata N, Li X, Chen MH, Li J, Hattori S.  Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities.  Int J Nanomedicine  2017  13:43-62  PubMed ID: 29317815
10915    Effect of Particle Size of Gold Nanoparticles on Matrix Metalloprotease Inhibition, Cytotoxicity and Genotoxicity  Journal of Biomaterials and Tissue Engineering,  2017  7, 139-146 
10949    Effect of 50-Hz Sinusoidal Magnetic Field on the Production of Superoxide Anion and the Expression of Heat-shock Protein 70 in RAW264 Cells  International Journal of Chemistry  2017  9 
4526  Yusuke Hiraku, Yoshihiro Nishikawa, Ning Ma, Tahmina Afroza, Kosuke Mizobuchi, Ryo Ishiyama, Yuta Matsunaga, Takamichi Ichinose, Shosuke Kawanishi, Mariko Murata  Nitrative DNA damage induced by carbon-black nanoparticles in macrophages and lung epithelial cells  Mutation Research/Genetic Toxicology and Environmental Mutagenesis  2017  818, 7-16  PubMed ID: 28477879
6471  Horigome S, Yoshida I, Ito S, Inohana S, Fushimi K, Nagai T, Yamaguchi A, Fujita K, Satoyama T, Katsuda SI, Suzuki S, Watai M, Hirose N, Mitsue T, Shirakawa H, Komai M.  Inhibitory effects of Kaempferia parviflora extract on monocyte adhesion and cellular reactive oxygen species production in human umbilical vein endothelial cells.  Eur J Nutr  2017  56(3):949-964  PubMed ID: 26704713
10050  Ha-Eun Yang, Yongjia Li, Akira Nishimura, Huei-Fen Jheng, Ana Yuliana, Ryuji Kitano-Ohue, Wataru Nomura, Nobuyuki Takahashi, Chu-Sook Kim, Rina Yu, Nahoko Kitamura, Si-Bum Park, Shigenobu Kishino, Jun Ogawa, Teruo Kawada, Tsuyoshi Goto  Synthesized Enone Fatty Acids Resembling Metabolites From Gut Microbiota Suppress Macrophage-Mediated Inflammation in Adipocytes  Mol Nutr Food Res  2017  Oct;61(10)  PubMed ID: 28544341
10076  Yusuke Kono, Taketo Nakai, Hitomi Taguchi, Takuya Fujita  Development of Magnetic Anionic Liposome/Atelocollagen Complexes for Efficient Magnetic Drug Targeting  Drug Deliv  2017  24(1):1740-1749  PubMed ID: 29141461
7077  Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake K, Takatsu K.  Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice.  Sci Rep  2016  6:23097  PubMed ID: 26975571
7094  Ryohei Hamaguchi, Yukihiro Kuroda  A Novel Biomarker for Cellular Toxicity and Phospholipid Accumulation by Cationic Amphiphilic Drugs.  Chromatography  2016  37:35-38 
7119  Taniguchi M, Ochiai A, Matsushima K, Tajima K, Kato T, Saitoh E, Tanaka T.  Endotoxin-neutralizing activity and mechanism of action of a cationic α-helical antimicrobial octadecapeptide derived from α-amylase of rice.  Peptides  2016  75:101-8  PubMed ID: 26643956
7148  Ohta T, Kusano K, Ido A, Miura C, Miura T.  Silkrose: A novel acidic polysaccharide from the silkmoth that can stimulate the innate immune response.  Carbohydr Polym  2016  136:995-1001  PubMed ID: 26572439
7157  Higuchi H, Shoji T, Murase Y, Iijima S, Nishijima K.  Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264.  Biosci. Biotechnol. Biochem.  2016  80:501-9  PubMed ID: 26540411
7230  Takayama S, Hashimoto K, Kokubu E, Taniguchi M, Tajima K, Ochiai A, Saitoh E, Saito A, Ishihara K, Kato T.  Inhibitory effects of a novel cationic dodecapeptide [CL(14-25)] derived from cyanate lyase of rice on endotoxic activities of LPSs from Escherichia coli and periodontopathic Aggregatibacter actinomycetemcomitans.  Microb. Pathog.  2016  94:2-11  PubMed ID: 26318142
7469  Hashimoto M, Sasaki J, Imazato S.  Investigation of the cytotoxicity of aluminum oxide nanoparticles and nanowires and their localization in L929 fibroblasts and RAW264 macrophages.  J. Biomed. Mater. Res. Part B Appl. Biomater.  2016  104:241-52  PubMed ID: 25715832
9520  Lu Y, Cao L, Egami Y, Kawai K, Araki N.  Cofilin contributes to phagocytosis of IgG-opsonized particles but not non-opsonized particles in RAW264 macrophages.  Microscopy (Oxf)  2016  65:233-42  PubMed ID: 26754560
9550  Takeuchi T, Nagasaka M, Shimizu M, Tamura M, Arata Y.  N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation.  Bone Rep  2016  5:15-21  PubMed ID: 28326343
9554  Kuno M, Li G, Moriura Y, Hino Y, Kawawaki J, Sakai H.  Acid-inducible proton influx currents in the plasma membrane of murine osteoclast-like cells.  Pflugers Arch.  2016  468:837-47  PubMed ID: 26843093
9564  Wada T, Sunaga H, Miyata K, Shirasaki H, Uchiyama Y, Shimba S.  Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression.  J. Biol. Chem.  2016  291:7004-16  PubMed ID: 26865635
9569  Pengjam Y, Madhyastha H, Madhyastha R, Yamaguchi Y, Nakajima Y, Maruyama M.  NF-κB pathway inhibition by anthrocyclic glycoside aloin is key event in preventing osteoclastogenesis in RAW264.7 cells.  Phytomedicine  2016  23:417-28  PubMed ID: 27002412
9607  Sugiyama K, Muroi M, Kinoshita M, Hamada O, Minai Y, Sugita-Konishi Y, Kamata Y, Tanamoto K.  NF-κB activation via MyD88-dependent Toll-like receptor signaling is inhibited by trichothecene mycotoxin deoxynivalenol.  J Toxicol Sci  2016  41:273-9  PubMed ID: 26961612
9609  Nakabayashi H, Aoyama S, Kawahara M, Nagamune T.  Differentiation signalobody: Demonstration of antigen-dependent osteoclast differentiation from a progenitor cell line.  J. Biosci. Bioeng.  2016  122:357-63  PubMed ID: 26979343
9612  Furuoka M, Ozaki K, Sadatomi D, Mamiya S, Yonezawa T, Tanimura S, Takeda K.  TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells.  J. Cell. Physiol.  2016  231:2761-7  PubMed ID: 26989816
9690  Elfeky M, Kaede R, Okamatsu-Ogura Y, Kimura K.  Adiponectin Inhibits LPS-Induced HMGB1 Release through an AMP Kinase and Heme Oxygenase-1-Dependent Pathway in RAW 264 Macrophage Cells.  Mediators Inflamm.  2016  2016:5701959  PubMed ID: 27313399
9692  Kure A, Nakagawa K, Kondo M, Kato S, Kimura F, Watanabe A, Shoji N, Hatanaka S, Tsushida T, Miyazawa T.  Metabolic Fate of Luteolin in Rats: Its Relationship to Anti-inflammatory Effect.  J. Agric. Food Chem.  2016  64:4246-54  PubMed ID: 27170112
9706  Zhang J, Hiromoto S, Yamazaki T, Niu J, Huang H, Jia G, Li H, Ding W, Yuan G.  Effect of macrophages on in vitro corrosion behavior of magnesium alloy.  J Biomed Mater Res A  2016  104:2476-87  PubMed ID: 27223576
9740  Sunarso , Toita R, Tsuru K, Ishikawa K.  A superhydrophilic titanium implant functionalized by ozone gas modulates bone marrow cell and macrophage responses.  J Mater Sci Mater Med  2016  27:127  PubMed ID: 27344451
9747  Arikawa M, Kakinuma Y, Noguchi T, Todaka H, Sato T.  Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation.  Eur. J. Pharmacol.  2016  789:17-26  PubMed ID: 27373848
9818  Kanzaki H, Shinohara F, Suzuki M, Wada S, Miyamoto Y, Yamaguchi Y, Katsumata Y, Makihira S, Kawai T, Taubman MA, Nakamura Y.  A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma.  Sci Rep  2016  6:32259  PubMed ID: 27573075
9882  Moriwaki S, Into T, Suzuki K, Miyauchi M, Takata T, Shibayama K, Niida S.  γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.  Sci Rep  2016  6:35930  PubMed ID: 27775020
9922  Yamawaki T, Ito E, Mukai A, Ueno M, Yamada J, Sotozono C, Kinoshita S, Hamuro J.  The Ingenious Interactions Between Macrophages and Functionally Plastic Retinal Pigment Epithelium Cells.  Invest. Ophthalmol. Vis. Sci.  2016  57:5945-5953  PubMed ID: 27820950
9969  Domon H, Oda M, Maekawa T, Nagai K, Takeda W, Terao Y.  Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis.  Sci Rep  2016  6:38013  PubMed ID: 27892542
10852  Kejuan Li, Xi Yang, Xuansheng Hu, Chao Han, Zhongfang Lei, Zhenya Zhang  In vitro antioxidant, immunomodulatory and anticancer activities of two fractions of aqueous extract from Helicteres angustifolia L. root  Journal of the Taiwan Institute of Chemical Engineers  2016  61:75-82 
10857    Clinical Evaluation of Novel Natural Polysaccharides Sacran as a Skincare Material for Atopic Dermatitis Patients   Journal of Cosmetics, Dermatological Sciences and Applications  2016  6, 9-18 
10869    Isolation and Biochemical Characterization of Mucus Proteins in Japanese Bunching Onion (Allium fistulosum) Green Leaves  Food Science and Technology Research  2016  22 
10109  Yusuke Kono, Ayu Iwasaki, Kenta Matsuoka, Takuya Fujita  Effect of Mechanical Agitation on Cationic Liposome Transport Across an Unstirred Water Layer in Caco-2 Cells  Biol Pharm Bull   2016  39(8):1293-9  PubMed ID: 27476939
12622  Goto T, Naknukool S, Yoshitake R, Hanafusa Y, Tokiwa S, Li Y, Sakamoto T, Nitta T, Kim M, Takahashi N, Yu R, Daiyasu H, Seno S, Matsuda H, Kawada T.  Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes  Cytokinec  2016  77:107-14  PubMed ID: 26556104
12858  Hashimoto M, Kawai K, Kawakami H, Imazato S.  Matrix metalloproteases inhibition and biocompatibility of gold and platinum nanoparticles  J Biomed Mater Res A  2016  104(1):209-17.  PubMed ID: 26282184
12885  Ichikawa N, Yamashita K, Funakoshi T, Ichihara S, Fukai M, Ogura M, Kobayashi N, Zaitsu M, Yoshida T, Shibasaki S, Koshizuka Y, Tsunetoshi Y, Sato M, Einama T, Ozaki M, Umezawa K, Suzuki T, Todo S.  Novel anti-inflammatory agent 3-[(dodecylthiocarbonyl)-methyl]-glutarimide ameliorates murine models of inflammatory bowel disease  Inflamm Res  2016  65(3):245-60  PubMed ID: 26683259
12936  Hayashida Y, Ikeda Y, Sawada K, Kawai K, Kato T, Kakehi Y, Araki N.  Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor  Int J Cancer  2016  139(3):700-11  PubMed ID: 26989815
12956  Nagahara H, Yamamoto A, Seno T, Obayashi H, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y.  Allograft inflammatory factor-1 in the pathogenesis of bleomycin-induced acute lung injury  Biosci Trends  2016  10(1):47-53.  PubMed ID: 26911661
7137  Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa TO, Kataoka Y, Yamamura K.  Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo.  Sci Rep  2015  5:17205  PubMed ID: 26598133
7221  Sawada Y, Sakamoto Y, Toh M, Ohara N, Hatanaka Y, Naka A, Kishimoto Y, Kondo K, Iida K.  Milk-derived peptide Val-Pro-Pro (VPP) inhibits obesity-induced adipose inflammation via an angiotensin-converting enzyme (ACE) dependent cascade.  Mol Nutr Food Res  2015  59:2502-10  PubMed ID: 26346532
7274  Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.  IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.  J. Clin. Invest.  2015  125:3269-79  PubMed ID: 26193638
7293  Tang L, Okamoto S, Shiuchi T, Toda C, Takagi K, Sato T, Saito K, Yokota S, Minokoshi Y.  Sympathetic Nerve Activity Maintains an Anti-Inflammatory State in Adipose Tissue in Male Mice by Inhibiting TNF-α Gene Expression in Macrophages.  Endocrinology  2015  156:3680-94  PubMed ID: 26132918
7321  Hashimoto M, Sasaki JI, Yamaguchi S, Kawai K, Kawakami H, Iwasaki Y, Imazato S.  Gold Nanoparticles Inhibit Matrix Metalloproteases without Cytotoxicity.  J. Dent. Res.  2015  94:1085-91  PubMed ID: 26040283
7340  Suzuki N, Takimoto K, Kawashima N.  Cathepsin K Inhibitor Regulates Inflammation and Bone Destruction in Experimentally Induced Rat Periapical Lesions.  J Endod  2015  41:1474-9  PubMed ID: 25990199
7420  Miyazaki T, Miyauchi S, Anada T, Tawada A, Suzuki O.  Chondroitin Sulfate-E Binds to Both Osteoactivin and Integrin αVβ3 and Inhibits Osteoclast Differentiation.  J. Cell. Biochem.  2015  116:2247-57  PubMed ID: 25820496
7448  Takeuchi T, Shimakawa G, Tamura M, Yokosawa H, Arata Y.  ISG15 regulates RANKL-induced osteoclastogenic differentiation of RAW264 cells.  Biol. Pharm. Bull.  2015  38:482-6  PubMed ID: 25757932
7451  Hashimoto M, Imazato S.  Cytotoxic and genotoxic characterization of aluminum and silicon oxide nanoparticles in macrophages.  Dent Mater  2015  31:556-64  PubMed ID: 25749564
7467  Kawabata K, Kato Y, Sakano T, Baba N, Hagiwara K, Tamura A, Baba S, Natsume M, Ohigashi H.  Effects of phytochemicals on in vitro anti-inflammatory activity of Bifidobacterium adolescentis.  Biosci. Biotechnol. Biochem.  2015  79:799-807  PubMed ID: 25721815
7492  Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M.  Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury.  Am. J. Physiol. Renal Physiol.  2015  308:F878-87  PubMed ID: 25656369
7505  Kim YI, Mohri S, Hirai S, Lin S, Goto T, Ohyane C, Sakamoto T, Takahashi H, Shibata D, Takahashi N, Kawada T.  Tomato extract suppresses the production of proinflammatory mediators induced by interaction between adipocytes and macrophages.  Biosci. Biotechnol. Biochem.  2015  79:82-7  PubMed ID: 25603813
7517  Taniguchi M, Ochiai A, Takahashi K, Nakamichi S, Nomoto T, Saitoh E, Kato T, Tanaka T.  Antimicrobial activity and mechanism of action of a novel cationic α-helical octadecapeptide derived from α-amylase of rice.  Biopolymers  2015  104:73-83  PubMed ID: 25581614
7526  F Shima, T Akagi, M Shudo, E Mochizuki, T Tsuda, S Kuwabata M Akashi  Interaction between living cells and polymeric particles: potential application of ionic liquid for evaluating the cellular uptake of biodegradable polymeric particles composed of poly(amino acid).  Polymer Journal  2015  47:631-638 
6343  Uto T, Tung NH, Taniyama R, Miyanowaki T, Morinaga O, Shoyama Y.  Anti-inflammatory Activity of Constituents Isolated from Aerial Part of Angelica acutiloba Kitagawa.  Phytother Res  2015  29(12):1956-63  PubMed ID: 26463105
10173  Yao-Tong Lai, Seiichi Ohta, Kazuki Akamatsu, Shin-Ichi Nakao, Yasuyuki Sakai, Taichi Ito  Size-dependent Interaction of Cells and Hemoglobin-Albumin Based Oxygen Carriers Prepared Using the SPG Membrane Emulsification Technique  Biotechnol Prog .   2015  31(6):1676-84  PubMed ID: 26399378
10195  Akihiko Nagao, Takashi Maoka, Hiroshi Ono, Eiichi Kotake-Nara, Miyuki Kobayashi, Mie Tomita  A 3-hydroxy β-End Group in Xanthophylls Is Preferentially Oxidized to a 3-oxo ε-End Group in Mammals  J Lipid Res  2015  56(2):449-62  PubMed ID: 25502844
12234  Masayori Hagimori, Naoko Mizuyama, Yoshinori Tominaga, Takahiro Mukai,Hideo Saji  A low-molecular-weight fluorescent sensor with Zn2+ dependent bathochromic shift of emission wavelength and its imaging in living cells  Dyes and Pigments  2015  113:205-209 
12237  Shiro Kato, Yuki Masuda, Morichika Konishi, Tadao Oikawa  Enantioselective analysis of D- and L-amino acids from mouse macrophages using high performance liquid chromatography  J Pharm Biomed Anal  2015  116:101-4  PubMed ID: 25982753
12245  Takashi Ando, Takayuki Komatsu, Yoshikazu Naiki, Takashi Yokochi, Daisuke Watanabe, Naoki Koide  Pretreatment of LPS inhibits IFN-β-induced STAT1 phosphorylation through SOCS3 induced by LPS  Biomed Pharmacother  2015  76:1-5  PubMed ID: 26653542
12252  Yoshiro Kato, Hideki Kamiya, Naoki Koide, Erdenezaya Odkhuu, Takayuki Komatsu, Atsuko Watarai, Masaki Kondo, Koichi Kato, Jiro Nakamura, Takashi Yokochi  Irbesartan attenuates production of high-mobility group box 1 in response to lipopolysaccharide via downregulation of interferon-β production  Int Immunopharmacol  2015  26(1):97-102  PubMed ID: 25817178
12259  Shusong Wu, Xi He, Xiaosong Wu, Si Qin, Jianhua He, Shirui Zhang, De-Xing Hou  Inhibitory effects of blue honeysuckle (Lonicera caerulea L) on adjuvant-induced arthritis in rats: Crosstalk of anti-inflammatory and antioxidant effects  J Functional Foods  2015  17:514-515 
6334  Itoh T, Tsuchida A, Muramatsu Y, Ninomiya M, Ando M, Tsukamasa Y, Koketsu M.  Antimicrobial and anti-inflammatory properties of nostocionone isolated from Nostoc commune Vauch and its derivatives against Propionibacterium acnes.  Anaerobe  2014  27:56-63  PubMed ID: 24699048
2777  Yamasaki T, Ariyoshi W, Okinaga T, Adachi Y, Hosokawa R, Mochizuki S, Sakurai K, Nishihara T.  The dectin 1 agonist curdlan regulates osteoclastogenesis by inhibiting nuclear factor of activated T cells cytoplasmic 1 (NFATc1) through Syk kinase.  J Biol Chem  2014  289(27):19191-203  PubMed ID: 24821724
6607  Nakazato R, Takarada T, Watanabe T, Nguyen BT, Ikeno S, Hinoi E, Yoneda Y.  Constitutive and functional expression of runt-related transcription factor-2 by microglial cells.  Neurochem Int  2014  74:24-35  PubMed ID: 24768841
9114  Erdenezaya Odkhuu, Takayuki Komatsu, Yoshikazu Naiki, Naoki Koide, Takashi Yokochi  Sendai Virus C Protein Inhibits Lipopolysaccharide-Induced Nitric Oxide Production Through Impairing Interferon-β Signaling  Int Immunopharmacol  2014  23 (1), 267-72  PubMed ID: 25242386
9323  Ran Zhao, Masayoshi Kamon, Kazuichi Sakamoto  (–)-Epigallocatechingallate Interferes RANKL/RANK Signal Pathway and Induces Apoptosis during Osteoclastogenesis in RAW264 Cell  Food and Nutrition Sciences  2014  5:107-116 
9349  Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo  Responses of RAW264.7 Macrophages to Water-Dispersible Gold and Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds  J Biomed Mater Res A  2014  102(6):1838-49  PubMed ID: 23784947
9351  Miki Tadaishi, Yoriko Nishide, Yuko Tousen, Marlena C Kruger, Yoshiko Ishimi  Cooperative Effects of Soy Isoflavones and Carotenoids on Osteoclast Formation  J Clin Biochem Nutr  2014  54(2):109-15  PubMed ID: 24688220
12850  Tada R, Koide Y, Yamamuro M, Tanaka R, Hidaka A, Nagao K, Aramaki Y.  Maleylated-BSA suppresses lipopolysaccharide-induced IL-6 production by activating the ERK-signaling pathway in murine RAW264.7 cells  Int Immunopharmacol  2014  19(1):5-9  PubMed ID: 24406428
7584  T. Atsumi, A. Iwashita, I. Ohtsuka, N. Kakiuchi, Y. Sasaki, M. Mikage, K. Toriizuka  Effects of Atractylodis Lanceae Rhizoma on inflammatory mediator production from the RAW264 macrophage cell line  J Traditional Medicines  2013  30:124-131 
5424  Takeshi KAWAHARA, Daichi NAKAYAMA, Keisuke TODA, Shyuichiro INAGAKI, Katsumi TANAKA, Hisako YASUI  Suppressive Effect of Wild Saccharomyces cerevisiae and Saccharomyces paradoxus Strains on Ige Production by Mouse Spleen Cells  Food Sci. Technol. Res  2013  19 (6), 1019 – 1027 
6086  Ito S, Tanaka Y, Nishio N, Thanasegaran S, Isobe K.  Establishment of self-renewable GM-CSF-dependent immature macrophages in vitro from murine bone marrow.  PLoS One  2013  8(10):e76943  PubMed ID: 24124601
6326  Horibe K, Nakamichi Y, Uehara S, Nakamura M, Koide M, Kobayashi Y, Takahashi N, Udagawa N.  Roles of cathelicidin-related antimicrobial peptide in murine osteoclastogenesis.  Immunology  2013  140(3):344-51  PubMed ID: 23826736
6466  Etoh T, Kim YP, Ohsaki A, Komiyama K, Hayashi M.  Inhibitory effect of erythraline on Toll-like receptor signaling pathway in RAW264.7 cells.  Biol Pharm Bull  2013  36(8):1363-9  PubMed ID: 23902980
6467  Etoh T, Kim YP, Tanaka H, Hayashi M.  Anti-inflammatory effect of berkeleyacetal C through the inhibition of interleukin-1 receptor-associated kinase-4 activity.  Eur J Pharmacol  2013  698(1-3):435-43  PubMed ID: 23127497
9096  Kyoko Ueda, Ryoko Kawabata, Takashi Irie, Yoshiaki Nakai, Yukinobu Tohya, Takemasa Sakaguchi  Inactivation of Pathogenic Viruses by Plant-Derived Tannins: Strong Effects of Extracts From Persimmon (Diospyros Kaki) on a Broad Range of Viruses  PLoS One  2013  8 (1), e55343  PubMed ID: 23372851
9100  Hiroki Ishikawa, Naoki Awano, Toshie Fukui, Hiraku Sasaki, Shigeru Kyuwa  The Protective Effects of Lactoferrin Against Murine Norovirus Infection Through Inhibition of Both Viral Attachment and Replication  Biochem Biophys Res Commun  2013  434 (4), 791-6  PubMed ID: 23603257
9169  Akari Ishisaka, Kyuichi Kawabata, Satomi Miki, Yuko Shiba, Shoko Minekawa, Tomomi Nishikawa, Rie Mukai, Junji Terao, Yoshichika Kawai  Mitochondrial Dysfunction Leads to Deconjugation of Quercetin Glucuronides in Inflammatory Macrophages  PLoS One  2013  8 (11), e80843  PubMed ID: 24260490
9256  Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo  Micromorphological Cellular Responses of MC3T3-E1 and RAW264.7 After Exposure to Water-Dispersible Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds  Dent Mater J  2013  32(5):725-33  PubMed ID: 24088827
9290  Hirohiko Okamura, Di Yang, Kaya Yoshida, Tatsuji Haneji  Protein Phosphatase 2A Cα Is Involved in Osteoclastogenesis by Regulating RANKL and OPG Expression in Osteoblasts  FEBS Lett  2013  587(1):48-53  PubMed ID: 23183242
12258  Kazuhiro Nakaya, Makoto Ayaori, Harumi Uto-Kondo, Grace Megumi Sotherden, Takafumi Nishida, Haruka Katamoto, Yuko Miura, Shunichi Takiguchi, Emi Yakushiji, Maki Iizuka, Masatsune Ogura, Makoto Sasaki, Makiko Yogo, Tomohiro Komatsu, Takeshi Adachi, Chizuko Maruyama, Katsunori Ikewaki  Overexpression of stearoyl-coenzyme A desaturase 1 in macrophages promotes reverse cholesterol transport  Biochim Biophys Acta  2013  1831(8):1402-11  PubMed ID: 23747827
4394  Suzuki S, Nishio SI, Ishii H, Sekido T, Takeshige K, Ohkubo Y, Hiwatashi D, Takeda T, Komatsu M.  Possible roles of the AP-1 site in the cytosolic T3 binding protein promoter and insights into its physiological significance.  Horm Metab Res  2013  45(7):501-6  PubMed ID: 23508717
13737  Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Masahiro Iijima, Kazuhiko Endo  Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Masahiro Iijima, Kazuhiko Endo  Journal of Biomaterials and Tissue Engineering  2013  4:51-58 
7589  Funakoshi T, Yamashita K, Ichikawa N, Fukai M, Suzuki T, Goto R, Oura T, Kobayashi N, Katsurada T, Ichihara S, Ozaki M, Umezawa K, Todo S.  A novel NF-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice.  J Crohns Colitis  2012  6:215-25  PubMed ID: 22325176
7599  Takano K, Sato K, Negishi Y, Aramaki Y.  Involvement of actin cytoskeleton in macrophage apoptosis induced by cationic liposomes.  Arch. Biochem. Biophys.  2012  518:89-94  PubMed ID: 22203089
7608  Takahashi K, Sugiyama T, Tokoro S, Neri P, Mori H.  Inhibition of interferon-γ-induced nitric oxide production by 10-hydroxy-trans-2-decenoic acid through inhibition of interferon regulatory factor-8 induction.  Cell. Immunol.  2012  273:73-8 
7609  Uto T, Morinaga O, Tanaka H, Shoyama Y.  Analysis of the synergistic effect of glycyrrhizin and other constituents in licorice extract on lipopolysaccharide-induced nitric oxide production using knock-out extract.  Biochem. Biophys. Res. Commun.  2012  417:473-8  PubMed ID: 22178686
7621  Nakagawa S, Arai Y, Kishida T, Hiraoka N, Tsuchida S, Inoue H, Sakai R, Mazda O, Kubo T.  Lansoprazole inhibits nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells.  Inflammation  2012  35:1062-8 
7639  Uto T, Qin GW, Morinaga O, Shoyama Y.  17-Hydroxy-jolkinolide B, a diterpenoid from Euphorbia fischeriana, inhibits inflammatory mediators but activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine macrophages.  Int. Immunopharmacol.  2012  12:101-9  PubMed ID: 22080918
7667  Uchida M, Oyanagi E, Kremenik MJ, Sasaki J, Yano H.  Interferon-beta, but not tumor necrosis factor-alpha, production in response to poly I:C is maintained despite exhaustive exercise in mice.  J Physiol Sci  2012  62:59-62  PubMed ID: 21968540
7678  Sugiyama T, Takahashi K, Tokoro S, Gotou T, Neri P, Mori H.  Inhibitory effect of 10-hydroxy-trans-2-decenoic acid on LPS-induced IL-6 production via reducing IκB-ζ expression.  Innate Immun  2012  18:429-37  PubMed ID: 21948282
4881  Honda H, Nagai Y, Matsunaga T, Saitoh S, Akashi-Takamura S, Hayashi H, Fujii I, Miyake K, Muraguchi A, Takatsu K.  Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner.  J Leukoc Biol  2012  91(6):967-76  PubMed ID: 22422925
5417  Echigo R, Shimohata N, Karatsu K, Yano F, Kayasuga-Kariya Y, Fujisawa A, Ohto T, Kita Y, Nakamura M, Suzuki S, Mochizuki M, Shimizu T, Chung UI, Sasaki N.  Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage.  J Transl Med  2012  10:80  PubMed ID: 22546323
6552  Takarada T, Takarada-Iemata M, Takahata Y, Yamada D, Yamamoto T, Nakamura Y, Hinoi E, Yoneda Y.  Osteoclastogenesis is negatively regulated by D-serine produced by osteoblasts.  J Cell Physiol  2012  227(10):3477-87  PubMed ID: 22252936
9092  Hiroyasu Tsutsuki, Kinnosuke Yahiro, Kotaro Suzuki, Akira Suto, Kohei Ogura, Sayaka Nagasawa, Hideshi Ihara, Takeshi Shimizu, Hiroshi Nakajima, Joel Moss, Masatoshi Noda  Subtilase Cytotoxin Enhances Escherichia Coli Survival in Macrophages by Suppression of Nitric Oxide Production Through the Inhibition of NF-κB Activation  Infect Immun  2012  80 (11), 3939-51  PubMed ID: 22949549
7633  Yamamoto H, Abe Y, Miyazato A, Tanno D, Tanaka M, Miyasaka T, Ishii K, Kawakami K.  Cryptococcus neoformans suppresses the activation of bone marrow-derived dendritic cells stimulated with its own DNA, but not with DNA from other fungi.  FEMS Immunol. Med. Microbiol.  2011  63:363-72  PubMed ID: 22092563
7702  Chen J, Qin S, Xiao J, Tanigawa S, Uto T, Hashimoto F, Fujii M, Hou DX.  A genome-wide microarray highlights the antiinflammatory genes targeted by oolong tea theasinensin A in macrophages.  Nutr Cancer  2011  63:1064-73  PubMed ID: 21864060
7725  Sakamoto T, Yamaguchi Y, Goto T, Takahashi N, Kawada T.  An in vitro analysis system using a fluorescence protein reporter for evaluating anti-inflammatory effects in macrophages.  Biosci. Biotechnol. Biochem.  2011  75:1582-7  PubMed ID: 21821941
7745  Itoh T, Hamada N, Terazawa R, Ito M, Ohno K, Ichihara M, Nozawa Y, Ito M.  Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.  Biochem. Biophys. Res. Commun.  2011  411:143-9  PubMed ID: 21723254
7750  Fujimoto A, Akifusa S, Hirofuji T, Yamashita Y.  Involvement of suppressor of cytokine signaling-1 in globular adiponectin-induced granulocyte colony-stimulating factor in RAW 264 cell.  Mol. Immunol.  2011  48:2052-8  PubMed ID: 21764457
7789  Abiko Y, Miura T, Phuc BH, Shinkai Y, Kumagai Y.  Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole.  Toxicol. Appl. Pharmacol.  2011  255:32-9  PubMed ID: 21651925
7794  Haque A, Noman AS, Koide N, Odkhuu E, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T.  An ADP ribosylation factor-GTPase activating protein negatively regulates the production of proinflammatory mediators in response to lipopolysaccharide.  Cancer Immunol. Immunother.  2011  60:1439-46  PubMed ID: 21644032
7850  Egusa H, Doi M, Saeki M, Fukuyasu S, Akashi Y, Yokota Y, Yatani H, Kamisaki Y.  The small molecule harmine regulates NFATc1 and Id2 expression in osteoclast progenitor cells.  Bone  2011  49:264-74  PubMed ID: 21504804
7851  Akagi T, Shima F, Akashi M.  Intracellular degradation and distribution of protein-encapsulated amphiphilic poly(amino acid) nanoparticles.  Biomaterials  2011  32:4959-67  PubMed ID: 21482432
7901  Yamazaki Y, Kawano Y.  Inhibitory effects of herbal alkaloids on the tumor necrosis factor-α and nitric oxide production in lipopolysaccharide-stimulated RAW264 macrophages.  Chem. Pharm. Bull.  2011  59:388-91  PubMed ID: 21372424
7921  Kurio N, Shimo T, Fukazawa T, Takaoka M, Okui T, Hassan NM, Honami T, Hatakeyama S, Ikeda M, Naomoto Y, Sasaki A.  Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo.  Exp. Cell Res.  2011  317:1134-46  PubMed ID: 21338601
7949  Arisaka M, Takano K, Negishi Y, Arima H, Aramaki Y.  Involvement of lipid rafts in macrophage apoptosis induced by cationic liposomes.  Arch. Biochem. Biophys.  2011  508:72-7  PubMed ID: 21315683
7966  Ichioka M, Suganami T, Tsuda N, Shirakawa I, Hirata Y, Satoh-Asahara N, Shimoda Y, Tanaka M, Kim-Saijo M, Miyamoto Y, Kamei Y, Sata M, Ogawa Y.  Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans.  Diabetes  2011  60:819-26  PubMed ID: 21282371
8010  Haque A, Koide N, Iftakhar-E-Khuda I, Noman AS, Odkhuu E, Badamtseren B, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Flavopiridol inhibits lipopolysaccharide-induced TNF-α production through inactivation of nuclear factor-κB and mitogen-activated protein kinases in the MyD88-dependent pathway.  Microbiol. Immunol.  2011  55:160-7  PubMed ID: 21204955
8052  Miyazaki T, Miyauchi S, Anada T, Imaizumi H, Suzuki O.  Evaluation of osteoclastic resorption activity using calcium phosphate coating combined with labeled polyanion.  Anal. Biochem.  2011  410:7-12  PubMed ID: 21078287
8066  Yonezawa T, Hasegawa S, Asai M, Ninomiya T, Sasaki T, Cha BY, Teruya T, Ozawa H, Yagasaki K, Nagai K, Woo JT.  Harmine, a β-carboline alkaloid, inhibits osteoclast differentiation and bone resorption in vitro and in vivo.  Eur. J. Pharmacol.  2011  650:511-8  PubMed ID: 21047508
8067  Kamio N, Akifusa S, Yamashita Y.  Diacylglycerol kinase alpha regulates globular adiponectin-induced reactive oxygen species.  Free Radic. Res.  2011  45:336-41  PubMed ID: 21034360
8135  Fukata N, Uchida K, Kusuda T, Koyabu M, Miyoshi H, Fukui T, Matsushita M, Nishio A, Tabata Y, Okazaki K.  The effective therapy of cyclosporine A with drug delivery system in experimental colitis.  J Drug Target  2011  19:458-67  PubMed ID: 20804404
8415  Tumurkhuu G, Koide N, Hiwasa T, Ookoshi M, Dagvadorj J, Abu Shadat Mohammod Noman, Iftakhar-E-Khuda I, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock.  Innate Immun  2011  17:97-105  PubMed ID: 20023007
8455  Shikama Y, Kuroishi T, Nagai Y, Iwakura Y, Shimauchi H, Takada H, Sugawara S, Endo Y.  Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).  Innate Immun  2011  17:3-15  PubMed ID: 19897531
8050  Hou DX, Masuzaki S, Tanigawa S, Hashimoto F, Chen J, Sogo T, Fujii M.  Oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (LPS)-activated mouse macrophages: structure-activity relationship and molecular mechanisms.  J. Agric. Food Chem.  2010  58:12735-43  PubMed ID: 21082860
8058  Oshima H, Hioki K, Popivanova BK, Oguma K, Van Rooijen N, Ishikawa TO, Oshima M.  Prostaglandin E? signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors.  Gastroenterology  2010  140:596-607.e7  PubMed ID: 21070778
8060  Ueda H, Ippoushi K, Takeuchi A.  Repeated oral administration of a squeezed ginger (Zingiber officinale) extract augmented the serum corticosterone level and had anti-inflammatory properties.  Biosci. Biotechnol. Biochem.  2010  74:2248-52  PubMed ID: 21071834
8085  Sakagami H, Zhou L, Kawano M, Thet MM, Tanaka S, Machino M, Amano S, Kuroshita R, Watanabe S, Chu Q, Wang QT, Kanamoto T, Terakubo S, Nakashima H, Sekine K, Shirataki Y, Zhang CH, Uesawa Y, Mohri K, Kitajima M, Oizumi H, Oizumi T.  Multiple biological complex of alkaline extract of the leaves of Sasa senanensis Rehder.  In Vivo  2010  24:735-43  PubMed ID: 20952742
8102  Lee JW, Mase N, Yonezawa T, Seo HJ, Jeon WB, Cha BY, Nagai K, Woo JT.  Palmatine attenuates osteoclast differentiation and function through inhibition of receptor activator of nuclear factor-κb ligand expression in osteoblast cells.  Biol. Pharm. Bull.  2010  33:1733-9  PubMed ID: 20930384
8113  Okui T, Shimo T, Fukazawa T, Kurio N, Hassan NM, Honami T, Takaoka M, Naomoto Y, Sasaki A.  Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction.  Mol. Cancer Ther.  2010  9:2960-9  PubMed ID: 20858724
8136  Shikama Y, Nagai Y, Okada S, Oizumi T, Shimauchi H, Sugawara S, Endo Y.  Pro-IL-1β accumulation in macrophages by alendronate and its prevention by clodronate.  Toxicol. Lett.  2010  199:123-8  PubMed ID: 20804833
8168  Yoshikawa K, Kokudo N, Hashimoto T, Yamamoto K, Inose T, Kimura T.  Novel phthalide compounds from Sparassis crispa (Hanabiratake), Hanabiratakelide A-C, exhibiting anti-cancer related activity.  Biol. Pharm. Bull.  2010  33:1355-9  PubMed ID: 20686231
8181  Nakatsuka R, Nozaki T, Shinohara M, Ohura K.  Dilazep decreases lipopolysaccharide-induced nitric oxide and TNF-alpha synthesis in RAW 264 cells.  J. Pharmacol. Sci.  2010  113:271-5  PubMed ID: 20647687
8208  Yano H, Uchida M, Nakai R, Ishida K, Kato Y, Kawanishi N, Shiva D.  Exhaustive exercise reduces TNF-α and IFN-α production in response to R-848 via toll-like receptor 7 in mice.  Eur. J. Appl. Physiol.  2010  110:797-803  PubMed ID: 20602110
8210  Shadat NM, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Retinoblastoma protein-interacting zinc finger 1 (RIZ1) regulates the proliferation of monocytic leukemia cells via activation of p53.  Cancer Invest.  2010  28:806-12  PubMed ID: 20594067
8214  Sakai H, Moriura Y, Notomi T, Kawawaki J, Ohnishi K, Kuno M.  Phospholipase C-dependent Ca2+-sensing pathways leading to endocytosis and inhibition of the plasma membrane vacuolar H+-ATPase in osteoclasts.  Am. J. Physiol., Cell Physiol.  2010  299:C570-8  PubMed ID: 20592242
8221  Yasuzaki Y, Yamada Y, Harashima H.  Mitochondrial matrix delivery using MITO-Porter, a liposome-based carrier that specifies fusion with mitochondrial membranes.  Biochem. Biophys. Res. Commun.  2010  397:181-6  PubMed ID: 20580633
8224  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nonaka K, Yamashita Y.  Involvement of the JAK-STAT pathway and SOCS3 in the regulation of adiponectin-generated reactive oxygen species in murine macrophage RAW 264 cells.  J. Cell. Biochem.  2010  111:597-606  PubMed ID: 20564237
8228  Kato Y, Koide N, Komatsu T, Tumurkhuu G, Dagvadorj J, Kato K, Yokochi T.  Metformin attenuates production of nitric oxide in response to lipopolysaccharide by inhibiting MyD88-independent pathway.  Horm. Metab. Res.  2010  42:632-6  PubMed ID: 20560107
8229  Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation.  Cell. Immunol.  2010  264:114-8  PubMed ID: 20557878
8249  Ohata S, Moriyama C, Yamashita A, Nishida T, Kusumoto C, Mochida S, Minami Y, Nakada J, Shomori K, Inagaki Y, Ohta Y, Matsura T.  Polaprezinc Protects Mice against Endotoxin Shock.  J Clin Biochem Nutr  2010  46:234-43  PubMed ID: 20490319
8258  Yamaguchi N, Hamachi T, Kamio N, Akifusa S, Masuda K, Nakamura Y, Nonaka K, Maeda K, Hanazawa S, Yamashita Y.  Expression levels of adiponectin receptors and periodontitis.  J. Periodont. Res.  2010  45:296-300  PubMed ID: 20470261
8273  Xiao G, Miyazato A, Abe Y, Zhang T, Nakamura K, Inden K, Tanaka M, Tanno D, Miyasaka T, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Yamamoto N, Kunishima H, Hirakata Y, Kaku M, Kawakami K.  Activation of myeloid dendritic cells by deoxynucleic acids from Cordyceps sinensis via a Toll-like receptor 9-dependent pathway.  Cell. Immunol.  2010  263:241-50  PubMed ID: 20451901
8282  Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Retinoblastoma protein-interacting zinc finger 1 (RIZ1) participates in RANKL-induced osteoclast formation via regulation of NFATc1 expression.  Immunol. Lett.  2010  131:166-9  PubMed ID: 20417662
8286  Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS.  Immunology  2010  131:59-66  PubMed ID: 20406300
8335  Kitagawa Y, Tohya Y, Ike F, Kajita A, Park SJ, Ishii Y, Kyuwa S, Yoshikawa Y.  Indirect ELISA and indirect immunofluorescent antibody assay for detecting the antibody against murine norovirus S7 in mice.  Exp. Anim.  2010  59:47-55  PubMed ID: 20224169
8368  Shimoda H, Shan SJ, Tanaka J, Seki A, Seo JW, Kasajima N, Tamura S, Ke Y, Murakami N.  Anti-inflammatory properties of red ginger (Zingiber officinale var. Rubra) extract and suppression of nitric oxide production by its constituents.  J Med Food  2010  13:156-62  PubMed ID: 20136450
8369  Tsukamoto H, Fukudome K, Takao S, Tsuneyoshi N, Kimoto M.  Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.  Int. Immunol.  2010  22:271-80  PubMed ID: 20133493
8372  Arisaka M, Nakamura T, Yamada A, Negishi Y, Aramaki Y.  Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells.  FEBS Lett.  2010  584:1016-20  PubMed ID: 20122929
8373  Hakozaki A, Yoda M, Tohmonda T, Furukawa M, Hikata T, Uchikawa S, Takaishi H, Matsumoto M, Chiba K, Horiuchi K, Toyama Y.  Receptor activator of NF-kappaB (RANK) ligand induces ectodomain shedding of RANK in murine RAW264.7 macrophages.  J. Immunol.  2010  184:2442-8  PubMed ID: 20118276
8396  Suzuki T, Chang MO, Kitajima M, Takaku H.  Baculovirus activates murine dendritic cells and induces non-specific NK cell and T cell immune responses.  Cell. Immunol.  2010  262:35-43  PubMed ID: 20060108
8426  Hirai S, Uemura T, Mizoguchi N, Lee JY, Taketani K, Nakano Y, Hoshino S, Tsuge N, Narukami T, Yu R, Takahashi N, Kawada T.  Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages.  Mol Nutr Food Res  2010  54:797-804  PubMed ID: 19998383
8462  Matsubara T, Ikeda F, Hata K, Nakanishi M, Okada M, Yasuda H, Nishimura R, Yoneda T.  Cbp recruitment of Csk into lipid rafts is critical to c-Src kinase activity and bone resorption in osteoclasts.  J. Bone Miner. Res.  2010  25:1068-76  PubMed ID: 19874196
8465  Sugiyama K, Muroi M, Tanamoto K, Nishijima M, Sugita-Konishi Y.  Deoxynivalenol and nivalenol inhibit lipopolysaccharide-induced nitric oxide production by mouse macrophage cells.  Toxicol. Lett.  2010  192:150-4  PubMed ID: 19857559
8488  Kishimoto Y, Tani M, Uto-Kondo H, Iizuka M, Saita E, Sone H, Kurata H, Kondo K.  Astaxanthin suppresses scavenger receptor expression and matrix metalloproteinase activity in macrophages.  Eur J Nutr  2010  49:119-26  PubMed ID: 19784539
5872  Chen J, Uto T, Tanigawa S, Yamada-Kato T, Fujii M, Hou DX.  Microarray-based determination of anti-inflammatory genes targeted by 6-(methylsulfinyl)hexyl isothiocyanate in macrophages.  Exp Ther Med  2010  1(1):33-40  PubMed ID: 23136589
8207  Kaori Yoshino, Kaoru Saijo, Chikako Noro and Yukio Nakamura  Development of a simple method to determine the mouse strain from which cultured cell lines originated  Interdisciplinary Bio Central   2010  2:0014 
8268  Miyazaki T, Miyauchi S, Tawada A, Anada T, Suzuki O.  Effect of chondroitin sulfate-E on the osteoclastic differentiation of RAW264 cells.  Dent Mater J  2010  29(4):403-10  PubMed ID: 20610874
8359  Lee JW, Ahn JY, Hasegawa S, Cha BY, Yonezawa T, Nagai K, Seo HJ, Jeon WB, Woo JT.  Inhibitory effect of luteolin on osteoclast differentiation and function.  Cytotechnology  2009  61:125-34  PubMed ID: 20162352
8495  Katsuura S, Imamura T, Bando N, Yamanishi R.  beta-Carotene and beta-cryptoxanthin but not lutein evoke redox and immune changes in RAW264 murine macrophages.  Mol Nutr Food Res  2009  53:1396-405  PubMed ID: 19760679
8549  Shioiri T, Muroi M, Hatao F, Nishida M, Ogawa T, Mimura Y, Seto Y, Kaminishi M, Tanamoto K.  Caspase-3 is activated and rapidly released from human umbilical vein endothelial cells in response to lipopolysaccharide.  Biochim. Biophys. Acta  2009  1792:1011-8  PubMed ID: 19559790
8550  Kamio N, Akifusa S, Yamaguchi N, Nonaka K, Yamashita Y.  Anti-inflammatory activity of a globular adiponectin function on RAW 264 cells stimulated by lipopolysaccharide from Aggregatibacter actinomycetemcomitans.  FEMS Immunol. Med. Microbiol.  2009  56:241-7  PubMed ID: 19552715
8551  Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Thalidomide inhibits lipopolysaccharide-induced nitric oxide production and prevents lipopolysaccharide-mediated lethality in mice.  FEMS Immunol. Med. Microbiol.  2009  56:204-11  PubMed ID: 19538513
8578  Miyazato A, Nakamura K, Yamamoto N, Mora-Montes HM, Tanaka M, Abe Y, Tanno D, Inden K, Gang X, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Mitsutake K, Gow NA, Kaku M, Kawakami K.  Toll-like receptor 9-dependent activation of myeloid dendritic cells by Deoxynucleic acids from Candida albicans.  Infect. Immun.  2009  77:3056-64  PubMed ID: 19433551
8589  Seddek Al, Mahmoud ME, Shiina T, Hirayama H, Iwami M, Miyazawa S, Nikami H, Takewaki T, Shimizu Y.  Extract from Calotropis procera latex activates murine macrophages.  J Nat Med  2009  63:297-303  PubMed ID: 19399577
8637  Tomimori Y, Mori K, Koide M, Nakamichi Y, Ninomiya T, Udagawa N, Yasuda H.  Evaluation of pharmaceuticals with a novel 50-hour animal model of bone loss.  J. Bone Miner. Res.  2009  24:1194-205  PubMed ID: 19257825
8640  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nishihara T, Yamashita Y.  Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2.  Free Radic. Biol. Med.  2009  46:1308-16  PubMed ID: 19250964
8641  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y.  Involvement of Ca(2+) in globular adiponectin-induced reactive oxygen species.  Biochem. Biophys. Res. Commun.  2009  381:649-53  PubMed ID: 19249286
8642  Hassan F, Islam S, Tumurkhuu G, Dagvadorj J, Naiki Y, Komatsu T, Koide N, Yoshida T, Yokochi T.  Involvement of interleukin-1 receptor-associated kinase (IRAK)-M in toll-like receptor (TLR) 7-mediated tolerance in RAW 264.7 macrophage-like cells.  Cell. Immunol.  2009  256:99-103  PubMed ID: 19251253
8648  Kasugai C, Morikawa A, Naiki Y, Koide N, Komatsu T, Yoshida T, Yokochi T.  Concanavalin A induces formation of osteoclast-like cells in RAW 264.7 mouse macrophage cells.  Immunopharmacol Immunotoxicol  2009  31:103-7  PubMed ID: 19234958
8654  Iftakhar-E-Khuda I, Koide N, Hassan F, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Novel mechanism of U18666A-induced tumour necrosis factor-alpha production in RAW 264.7 macrophage cells.  Clin. Exp. Immunol.  2009  155:552-8  PubMed ID: 19220841
8663  Noman AS, Koide N, Hassan F, I-E-Khuda I, Dagvadorj J, Tumurkhuu G, Islam S, Naiki Y, Yoshida T, Yokochi T.  Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression.  Innate Immun  2009  15:33-41  PubMed ID: 19201823
8691  Inden K, Kaneko J, Miyazato A, Yamamoto N, Mouri S, Shibuya Y, Nakamura K, Aoyagi T, Hatta M, Kunishima H, Hirakata Y, Itoh Y, Kaku M, Kawakami K.  Toll-like receptor 4-dependent activation of myeloid dendritic cells by leukocidin of Staphylococcus aureus.  Microbes Infect.  2009  11:245-53  PubMed ID: 19111627
8739  Nakamura T, Kodama N, Arai Y, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ishikawa T, Ueno K, Yano S.  Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7.  J Nat Med  2009  63:21-7  PubMed ID: 18636311
8740  Nakamura T, Kodama N, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ueno K, Ishikawa T, Yano S.  Inhibitory effect of the extracts from Thai medicinal plants on iNOS expression in mouse macrophage RAW 264.7.  J Nat Med  2009  63:107-10  PubMed ID: 18626726
8742  Nakamura T, Kodama N, Oda M, Tsuchiya S, Arai Y, Kumamoto T, Ishikawa T, Ueno K, Yano S.  The structure-activity relationship between oxycoumarin derivatives showing inhibitory effects on iNOS in mouse macrophage RAW264.7 cells.  J Nat Med  2009  63:15-20  PubMed ID: 18607531
10145  Murakami M, Kawachi H, Ogawa K, Nishino Y, Funaba M.  Receptor expression modulates the specificity of transforming growth factor-beta signaling pathways.  Genes Cells  2009  14(4):469-82  PubMed ID: 19335617
8170  Tsuji M, Yamamoto H, Sato T, Mizuha Y, Kawai Y, Taketani Y, Kato S, Terao J, Inakuma T, Takeda E.  Dietary quercetin inhibits bone loss without effect on the uterus in ovariectomized mice.  J Bone Miner Metab  2009  27(6):673-81  PubMed ID: 19495926
11020  Masayuki TAIRA et al  DNA Microarray Analyses of the Effects of LPS-stimulation and IC50 Nickel Ions on Gene Expressions of Mouse Macrophage-like Cell Line RAW264  Nano Biomedicine  2009  1:59-69 
12295  Ken Shirato, Takako Kizaki, Takuya Sakurai, Jun-Etsu Ogasawara, Yoshinaga Ishibashi, Takehiko Iijima, Chikako Okada, Izumi Noguchi, Kazuhiko Imaizumi, Naoyuki Taniguchi, Hideki Ohno  Hypoxia-inducible factor-1alpha suppresses the expression of macrophage scavenger receptor 1  Pflugers Arch  2009  459(1):93-103  PubMed ID: 19641936
8731  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y.  Regulation of globular adiponectin-induced apoptosis by reactive oxygen/nitrogen species in RAW264 macrophages.  Free Radic. Biol. Med.  2008  45:1326-39  PubMed ID: 18775488
8754  Yoshida H, Kwon AH, Habara K, Yamada M, Kaibori M, Kamiyama Y, Nishizawa M, Ito S, Okumura T.  Edaravone inhibits the induction of iNOS gene expression at transcriptional and posttranscriptional steps in murine macrophages.  Shock  2008  30:734-9  PubMed ID: 18496239
5375  Nishida K, Kuchiiwa S, Oiso S, Futagawa T, Masuda S, Takeda Y, Yamada K.  Up-regulation of matrix metalloproteinase-3 in the dorsal root ganglion of rats with paclitaxel-induced neuropathy.  Cancer Sci  2008  99(8):1618-25  PubMed ID: 18754875
3578  Ando M, Tu W, Nishijima K, Iijima S.  Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs.  Biochem Biophys Res Commun  2008  369(3):878-83  PubMed ID: 18325328
6521  Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H.  Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9.  J Biol Chem  2008  283(36):24682-9  PubMed ID: 18617520
13756  Murakami M, Kondo S, Funaba M.  Expression and function of alternative splice variants of the mouse TGF-beta type I receptor  Cell Biol Int  2008  32(7):848-54  PubMed ID: 18474439
8815  Taira M, Sasaki K, Saitoh S, Nezu T, Sasaki M, Kimura S, Terasaki K, Sera K, Narushima T, Araki Y.  Accumulation of element Ti in macrophage-like RAW264 cells cultured in medium with 1 ppm Ti and effects on cell viability, SOD production and TNF-alpha secretion.  Dent Mater J  2007  25:726-32  PubMed ID: 17338307
8850  Yamaguchi N, Kukita T, Li YJ, Martinez Argueta JG, Saito T, Hanazawa S, Yamashita Y.  Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.  FEMS Immunol. Med. Microbiol.  2007  49:28-34  PubMed ID: 17094790
4889  Takayoshi Suganami, Kanami Tanimoto-Koyama, Junko Nishida, Michiko Itoh, Xunmei Yuan, Shinji Mizuarai, Hidehito Kotani, Shoji Yamaoka, Kensuke Miyake, Seiichiro Aoe, Yasutomi Kamei and Yoshihiro Ogawa  Role of the Toll-like Receptor 4/NF-κB Pathway in Saturated Fatty Acid−Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages  Arterioscler Thromb Vasc Biol  2007  27:84-91  PubMed ID: 17082484
7269  Takarada T, Hinoi E, Kambe Y, Sahara K, Kurokawa S, Takahata Y, Yoneda Y.  Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative cytotoxicity of ascorbic acid.  Eur J Pharmacol  2007  575(1-3):1-11  PubMed ID: 17698058
7349  Ito M, Haito S, Furumoto M, Uehata Y, Sakurai A, Segawa H, Tatsumi S, Kuwahata M, Miyamoto K.  Unique uptake and efflux systems of inorganic phosphate in osteoclast-like cells.  Am J Physiol Cell Physiol  2007  292(1):C526-34  PubMed ID: 16971494
7387  Murakami Y, Hirata A, Ito S, Shoji M, Tanaka S, Yasui T, Machino M, Fujisawa S.  Re-evaluation of cyclooxygenase-2-inhibiting activity of vanillin and guaiacol in macrophages stimulated with lipopolysaccharide.  Anticancer Res  2007  27(2):801-7  PubMed ID: 17465205
12320  Masayori Hagimori, Eri Hatabe, Kohei Sano, Hirotaka Miyazaki, Hitoshi Sasaki, Hideo Saji, Takahiro Mukai  An Activatable Fluorescent γ-Polyglutamic Acid Complex for Sentinel Lymph Node Imaging  Biol Pharm Bull  2007  40(3):297-302  PubMed ID: 28250270
12814  Uto T, Fujii M, Hou DX.  Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-gamma and 12-O-tetradecanoylphorbol-13-acetate  Oncol Rep  2007  17(1):233-8  PubMed ID: 17143503
8917  Soji Fukumoto, Paramasari Dirgahayu, Kozue Nunomura, Haruyo Matsuura andKazumitsu Hirai  Suppression of LPS-induced Cyclooxygenase-2 (cox-2) Gene Expression in Mouse Macrophages by Excretory/Secretory Products of Spirometra erinaceieuropaei Plerocercoids  Yonago Acta Med.  2006  49:39-47 
6489  Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A.  TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.  Arthritis Res Ther  2006  8(5):R146  PubMed ID: 16945157
7020  Murakami Y, Shoji M, Ogiwara T, Tanaka S, Yokoe I, Fujisawa S.  Preventive effect of ortho dimer of butylated hydroxyanisole on activator protein-1 activation and cyclooxygenase-2 expression in macrophages stimulated by fimbriae of Porphyromonas gingivalis, an oral anaerobe.  Anticancer Res  2006  26(4B):2915-20  PubMed ID: 16886613
7039  Funaba M, Nakaya K, Ikeda T, Murakami M, Tsuchida K, Sugino H.  Requirement of Smad3 for mast cell growth.  Cell Immunol  2006  240(1):47-52  PubMed ID: 16839529
13660  Kimura Y, Sumiyoshi M, Suzuki T, Sakanaka M.  Antitumor and antimetastatic activity of a novel water-soluble low molecular weight beta-1, 3-D-glucan (branch beta-1,6) isolated from Aureobasidium pullulans 1A1 strain black yeast  Anticancer Res  2006  26(6B):4131-41  PubMed ID: 17201124
13729  Imamura T, Bando N, Yamanishi R.  Beta-carotene modulates the immunological function of RAW264, a murine macrophage cell line, by enhancing the level of intracellular glutathione  Biosci Biotechnol Biochem  2006  70(9):2112-20.  PubMed ID: 16960387
3160  Wei, Ping, Taniguchi, Susumu, Sakai, Yoshiyuki, Imamura, Minako, Inoguchi, Toyoshi, Nawata, Hajime, Oda, Shinya, Nakabeppu, Yusaku, Nishimura, Junji, Ikuyama, Shoichiro  Expression of adipose differentiation-related protein (ADRP) is conjointly regulated by PU.1 and AP-1 in macrophages.  J Biochem  2005  138:399-412  PubMed ID: 16272134
2903  Shimomura-Shimizu M, Sugiyama K, Muroi M, Tanamoto K  Alachlor and carbaryl suppress lipopolysaccharide-induced iNOS expression by differentially inhibiting NF-kappaB activation.  Biochem Biophys Res Commun  2005  332:793-9  PubMed ID: 15907790
2922  Musikacharoen, Tipayaratn, Oguma, Asako, Yoshikai, Yasunobu, Chiba, Norika, Masuda, Akio, Matsuguchi, Tetsuya  Interleukin-15 induces IL-12 receptor beta1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling.  Blood  2005  105:711-20  PubMed ID: 15345588
3365  Ito, Mikiko, Matsuka, Naoko, Izuka, Michiyo, Haito, Sakiko, Sakai, Yuko, Nakamura, Rie, Segawa, Hiroko, Kuwahata, Masashi, Yamamoto, Hironori, Pike, Wesley J, Miyamoto, Ken-ichi  Characterization of inorganic phosphate transport in osteoclast-like cells.  Am J Physiol Cell Physiol  2005  288:C921-31  PubMed ID: 15601753
3392  Aki, Daisuke, Mashima, Ryuichi, Saeki, Kazuko, Minoda, Yasumasa, Yamauchi, Moriyasu, Yoshimura, Akihiko  Modulation of TLR signalling by the C-terminal Src kinase (Csk) in macrophages.  Genes Cells  2005  10:357-68  PubMed ID: 15773898
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1812  木戸敏孝、福田一典、緒形孝弘、植木俊之、山本雅浩、遠藤徹  LPS刺激マクロファージの一酸化窒素産生に対する黄苓水エキスによる抑制効果と活性成分の検討  日本炎症学会雑誌  1994  14:221-227 

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