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15333
Tatsuya Murakami, Masashi Nakatani, Masahiro Kokubo, Hirotaka Nakatsuji, Mami Inada, Hiroshi Imahori, Masako Yudasaka, Sumio Iijima, Kunihiro Tsuchida
Mechanism of Cell Interactions with Water-Dispersed Carbon Nanohorns
Nanoscience and Nanotechnology Letters
2913
5:402-407
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20526
Aki T, Funakoshi T, Unuma K, Uemura K.
Inverse regulation of GSDMD and GSDME gene expression during LPS-induced pyroptosis in RAW264.7 macrophage cells.
Apoptosis
2022
PubMed ID: 35006493
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13272
Tanaka KI, Kubota M, Shimoda M, Hayase T, Miyaguchi M, Kobayashi N, Ikeda M, Ishima Y, Kawahara M.
Thioredoxin-albumin fusion protein prevents urban aerosol-induced lung injury via suppressing oxidative stress-related neutrophil extracellular trap formation.
Environ Pollut
2021
PubMed ID: 33065363
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13373
Kuriyama T, Fukuma Y, Imashiro C, Kabayama K, Kurashina Y, Takemura K.
Detachment of RAW264.7 macrophages from a culture dish using ultrasound excited by a Langevin transducer.
J Biosci Bioeng
2021
131(3):320-325
PubMed ID: 33250410
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13464
Sugiyama T, Hobro AJ, Pavillon N, Umakoshi T, Verma P, Smith N.
Label-free Raman mapping of saturated and unsaturated fatty acid uptake, storage, and return toward baseline levels in macrophages
Analyst
2021
146(4):1268-1280
PubMed ID: 33346264
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20004
Wada Y, Iyoda M, Matsumoto K, Suzuki T, Tachibana S, Kanazawa N, Honda H.
Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice.
PLoS One
2021
16(1):e0245340
PubMed ID: 33428678
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20009
Li SW, Takahara T, Que W, Fujino M, Guo WZ, Hirano SI, Ye LP, Li XK.
Hydrogen-rich water protects liver injury in nonalcoholic steatohepatitis though HO-1 enhancement via IL-10 and Sirt 1 signaling.
Am J Physiol Gastrointest Liver Physiol
2021
PubMed ID: 33439102
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20023
Madhyastha R, Madhyastha H, Nurrahmah QI, Purbasari B, Maruyama M, Nakajima Y.
MicroRNA 21 Elicits a Pro-inflammatory Response in Macrophages, with Exosomes Functioning as Delivery Vehicles.
Inflammation
2021
PubMed ID: 33501624
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20065
Ma'mag LK, Zintchem AAA, Théodora KK, de Théodore AA, Lauve TY, Frédérich M, Bikobo DSN, Pegnyemb DE.
Antiplasmodial and antileishmanial inhibitory activity of triterpenes and steroidal alkaloid from the leaves of Funtumia elastica (Preuss) Stapf (Apocynaceae).
Fitoterapia
2021
104869
PubMed ID: 33657429
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20088
Nurrahmah QI, Madhyastha R, Madhyastha H, Purbasari B, Maruyama M, Nakajima Y.
Retinoic acid abrogates LPS-induced inflammatory response via negative regulation of NF-kappa B/miR-21 signaling.
Immunopharmacol Immunotoxicol
2021
1-10
PubMed ID: 33757404
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20176
Pengjam Y, Prajantasen T, Tonwong N, Panichayupakaranant P.
Downregulation of miR-21 gene expression by CRE-Ter to modulate osteoclastogenesis: De Novo mechanism.
Biochem Biophys Rep
2021
26:101002
PubMed ID: 33997317
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20196
Sano K, Miki M, Tanaka T, Munemura M, Munekane M, Yamasaki T, Mukai T.
Electrostatically self-assembled gold nanorods with chondroitin sulfate for targeted photothermal therapy for melanoma.
Photodiagnosis Photodyn Ther
2021
102402
PubMed ID: 34144259
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20197
Ju N, Hayashi H, Shimamura M, Yoshida S, Nakamaru R, Nakagami H, Morishita R, Rakugi H.
Prevention of Acute Lung Injury by a Novel CD14-Inhibitory Receptor Activator of the NF-κB Ligand Peptide in Mice.
Immunohorizons
2021
5(6):438-447
PubMed ID: 34131020
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20199
Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.
Extracellular mRNA transported to the nucleus exerts translation-independent function.
Nat Commun
2021
12(1):3655
PubMed ID: 34135341
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20243
Hattori H, Takaoka K, Ueta M, Oshitani M, Tamaoka J, Noguchi K, Kishimoto H.
Senescent RAW264.7 cells exhibit increased production of nitric oxide and release inducible nitric oxide synthase in exosomes.
Mol Med Rep
2021
24(3)
PubMed ID: 34318909
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20258
Yokota S, Matsumae G, Shimizu T, Hasegawa T, Ebata T, Takahashi D, Heguo C, Tian Y, Alhasan H, Takahata M, Kadoya K, Terkawi MA, Iwasaki N.
Cardiotrophin like cytokine factor 1 (CLCF1) alleviates bone loss in osteoporosis mouse models by suppressing osteoclast differentiation through activating interferon signaling and repressing the nuclear factor-κB signaling pathway.
Bone
2021
116140
PubMed ID: 34364014
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15168
Hangai S, Kawamura T, Kimura Y, Chang CY, Hibino S, Yamamoto D, Nakai Y, Tateishi R, Oshima M, Oshima H, Kodama T, Moriya K, Koike K, Yanai H, Taniguchi T.
Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells
Nat Immunol
2021
22(8):947-957
PubMed ID: 34239121
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20285
Pavillon N, Smith NI.
Deriving accurate molecular indicators of protein synthesis through Raman-based sparse classification.
Analyst
2021
146(11):3633-3641
PubMed ID: 33949431
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20313
Yamaguchi M, Takagi K, Sato M, Sato A, Miki Y, Onodera Y, Miyashita M, Sasano H, Suzuki T.
Androgens enhance the ability of intratumoral macrophages to promote breast cancer progression.
Oncol Rep
2021
46(3)
PubMed ID: 34278480
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20315
Cheng TY, Lin YJ, Saburi W, Vieths S, Scheurer S, Schülke S, Toda M.
β-(1→4)-Mannobiose Acts as an Immunostimulatory Molecule in Murine Dendritic Cells by Binding the TLR4/MD-2 Complex.
Cells
2021
10(7)
PubMed ID: 34359943
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15263
Hiromu Ito
Peroxynitrite Production Induced by LPS and X-ray Treatment Enhances Cellular Incorporation of Porphyrin in Mouse RAW264 Macrophages
Applied Sciences
2021
11:3503
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15264
Yamasaki M, Yamasaki Y, Furusho R, Kimura H, Kamei I, Sonoda H, Ikeda M, Oshima T, Ogawa K, Nishiyama K.
Onion ( Allium cepa L.)-Derived Nanoparticles Inhibited LPS-Induced Nitrate Production, However, Their Intracellular Incorporation by Endocytosis Was Not Involved in This Effect on RAW264 Cells
Molecules
2021
26(9):2763
PubMed ID: 34067155
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15265
Nipitpon Srimai, Wasawat Kiatarkom, Hidetake Miyata
Evaluation of the Effects of Hypo-Magnetic Fields on Mouse Macrophage RAW264 Cells
International Journal of Chemistry
2021
13:12-20
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15266
Kitazawa R, Haraguchi R, Kohara Y, Kitazawa S.
RANK- NFATc1 signaling forms positive feedback loop on rank gene expression via functional NFATc1 responsive element in rank gene promoter
Biochem Biophys Res Commun
2021
572:86-91
PubMed ID: 34358968
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15267
Noguchi T, Hidaka K, Kobayashi S, Matsumoto K, Yoshioka M, Hu X, Maloney DJ, Yang SM, Kato S.
A quinazoline-based bromodomain inhibitor, CN210, ameliorates indomethacin-induced ileitis in mice by inhibiting inflammatory cytokine expression
Drug Dev Res
2021
21 Jun 1
PubMed ID: 34075610
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15268
Tsuchiya K, Hosojima S, Hara H, Kushiyama H, Mahib MR, Kinoshita T, Suda T.
Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes
Cell Rep
2021
34(12):108887
PubMed ID: 33761363
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15269
Takahashi K, Mizukami H, Osonoi S, Ogasawara S, Hara Y, Kudoh K, Takeuchi Y, Sasaki T, Daimon M, Yagihashi S.
Inhibitory effects of xanthine oxidase inhibitor, topiroxostat, on development of neuropathy in db/db mice
Neurobiol Dis
2021
155:105392
PubMed ID: 34000416
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15270
Shinjyo N, Nakayama H, Li L, Ishimaru K, Hikosaka K, Suzuki N, Yoshida H, Norose K.
Hypericum perforatum extract and hyperforin inhibit the growth of neurotropic parasite Toxoplasma gondii and infection-induced inflammatory responses of glial cells in vitro
J Ethnopharmacol
2021
267:113525
PubMed ID: 33129946
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15271
Kimura H, Tokuyama-Nakai S, Hirabayashi Y, Ishihara T, Jisaka M, Yokota K.
Anti-inflammatory and bioavailability studies on dietary 3,5,4'-trihydroxy-6,7-methylenedioxyflavone-O-glycosides and their aglycone from indigo leaves in a murine model of inflammatory bowel disease
J Pharm Biomed Anal
2021
193:113716
PubMed ID: 33152603
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15272
Xi Yang, Satoru Komatsu, Sheethal Reghu, Eijiro Miyako
Optically activatable photosynthetic bacteria-based highly tumor specific immunotheranostics
Nano Today
2021
37:101100
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15276
Yoshida H, Tsuhako R, Sugita C, Kurokawa M.
Glucosyl Hesperidin Has an Anti-diabetic Effect in High-Fat Diet-Induced Obese Mice
Biol Pharm Bull
2021
44(3):422-430
PubMed ID: 33642550
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15280
Yukino Tsunekage, Masatoshi Takeiri, Yuri Yoshioka, Shinichi Matsumura, Yoshihide Kimura, Kohsuke Kataoka
Nasturtium officinale Extract Suppresses Osteoclastogenesis in RAW 264 Cells by Inhibiting IκB-Kinase β
Natural Product Communications
2021
16:1934578X2110206
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15285
Fuchi Y, Murase H, Kai R, Kurata K, Karasawa S, Sasaki S.
Artificial Host Molecules to Covalently Capture 8-Nitro-cGMP in Neutral Aqueous Solutions and in Cells
Bioconjug Chem
2021
32(2):385-393
PubMed ID: 33529519
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20345
Thein HSS, Hashimoto K, Kawashima N, Noda S, Okiji T.
Evaluation of the anti-inflammatory effects of surface-reaction-type pre-reacted glass-ionomer filler containing root canal sealer in lipopolysaccharide-stimulated RAW264.7 macrophages.
Dent Mater J
2021
PubMed ID: 34602587
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20352
Takenaga K, Koshikawa N, Nagase H.
Intercellular transfer of mitochondrial DNA carrying metastasis-enhancing pathogenic mutations from high- to low-metastatic tumor cells and stromal cells via extracellular vesicles.
BMC Mol Cell Biol
2021
22(1):52
PubMed ID: 34615464
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15684
Kwaffo YA, Sarpong-Duah M, Owusu-Boateng K, Gbewonyo WS, Adjimani JP, Mosi L.
Natural antioxidants attenuate mycolactone toxicity to RAW 264.7 macrophages
Exp Biol Med (Maywood)
2021
246(17):1884-1894
PubMed ID: 34038223
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20457
Hiyoshi M, Takahashi N, Eltalkhawy YM, Noyori O, Lotfi S, Panaampon J, Okada S, Tanaka Y, Ueno T, Fujisawa JI, Sato Y, Suzuki T, Hasegawa H, Tokunaga M, Satou Y, Yasunaga JI, Matsuoka M, Utsunomiya A, Suzu S.
M-Sec induced by HTLV-1 mediates an efficient viral transmission.
PLoS Pathog
2021
17(11):e1010126
PubMed ID: 34843591
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15891
Rimpei Kamegawa, Mitsuru Naito, Satoshi Uchida, Hyun Jin Kim, Beob Soo Kim, Kanjiro Miyata
Bioinspired Silicification of mRNA-Loaded Polyion Complexes for Macrophage-Targeted mRNA Delivery
ACS Applied Bio Materials
2021
4:7790-7799
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20495
Safitri FA, Tu ATT, Hoshi K, Shobo M, Zhao D, Witarto AB, Sumarsono SH, Giri-Rachman EA, Tsukakoshi K, Ikebukuro K, Yamazaki T.
Enhancement of the Immunostimulatory Effect of Phosphodiester CpG Oligodeoxynucleotides by an Antiparallel Guanine-Quadruplex Structural Scaffold.
Biomolecules
2021
11(11)
PubMed ID: 34827615
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13434
Frederick Ayertey, Ebenezer Ofori-Attah, Stephen Antwi, Michael Amoa-Bosompem, Georgina Djameh, Nathaniel Lartey Lartey, Mistuko Ohashi, Kwadwo Asamoah Kusi, Alfred Ampomah Appiah, Regina Appiah-Opong, Laud Kenneth Okine
Anti-inflammatory activity and mechanism of action of ethanolic leaf extract of Morinda lucida Benth
Journal of Traditional and Complementary Medicine
2020/1/1
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11608
Tsuhako R, Yoshida H, Sugita C, Kurokawa M.
Naringenin suppresses neutrophil infiltration into adipose tissue in high-fat diet-induced obese mice.
J Nat Med
2020
74(1):229-237.
PubMed ID: 31218550
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11704
Miori Tanaka, Ayako Sugama, Kanako Sumi, Kozue Shimizu, Yoshimi Kishimoto, Kazuo Kondo, Kaoruko Iida
Gallic acid regulates adipocyte hypertrophy and suppresses inflammatory gene expression induced by the paracrine interaction between adipocytes and macrophages in vitro and in vivo
Nutrition Research
2020
73:58-66
PubMed ID: 31841748
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11757
Manabe Y, Takii Y, Sugawara T.
Siphonaxanthin, a carotenoid from green algae, suppresses advanced glycation end product-induced inflammatory responses.
J Nat Med
2020
74(1):127-134
PubMed ID: 31432315
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11863
Yamada K, Takizawa S, Ohgaku Y, Asami T, Furuya K, Yamamoto K, Takahashi F, Hamajima C, Inaba C, Endo K, Matsui R, Kitamura H, Tanaka S.
MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages.
Gene
2020
PubMed ID: 31654705
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6906
Shinjyo N, Nakayama H, Ishimaru K, Hikosaka K, Mi-Ichi F, Norose K, Yoshida H.
Hypericum erectum alcoholic extract inhibits Toxoplasma growth and Entamoeba encystation: an exploratory study on the anti-protozoan potential.
J Nat Med
2020
74(1):294-305
PubMed ID: 31728823
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11900
Fujihara Y, Abe T, Asawa Y, Nishizawa S, Saijo H, Hikita A, Hoshi K.
Influence of Damage-Associated Molecular Patterns from Chondrocytes in Tissue-Engineered Cartilage.
Tissue Eng Part A
2020
PubMed ID: 31724485
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12001
Yoshimoto Y, Jo JI, Tabata Y.
Preparation of antibody-immobilized gelatin nanospheres incorporating a molecular beacon to visualize the biological function of macrophages.
Regen Ther
2020
PubMed ID: 31970268
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12006
Kohara Y, Haraguchi R, Kitazawa R, Kitazawa S.
Knockdown of Lrp1 in RAW264 cells inhibits osteoclast differentiation and osteoclast-osteoblast interactions in vitro.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31964526
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12009
Bandow K, Hasegawa H, Tomomura M, Tomomura A.
Caldecrin inhibits lipopolysaccharide-induced pro-inflammatory cytokines and M1 macrophage polarization through the immunoreceptor triggering receptor expressed in myeloid cells-2.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31973822
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12016
Kawakubo M, Tanaka M, Ochi K, Watanabe A, Saka-Tanaka M, Kanamori Y, Yoshioka N, Yamashita S, Goto M, Itoh M, Shirakawa I, Kanai S, Suzuki H, Sawada M, Ito A, Ishigami M, Fujishiro M, Arima H, Ogawa Y, Suganami T.
Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects.
Sci Rep
2020
PubMed ID: 31969650
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12026
Tanaka M, Miyake H, Oka S, Maeda S, Iwasaki K, Mukai T.
Effects of charged lipids on the physicochemical and biological properties of lipid-styrene maleic acid copolymer discoidal particles.
Biochim Biophys Acta Biomembr
2020
PubMed ID: 32004520
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12048
Funakoshi-Tago M, Nonaka Y, Tago K, Takeda M, Ishihara Y, Sakai A, Matsutaka M, Kobata K, Tamura H.
Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2.
Sci Rep
2020
PubMed ID: 32054966
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12058
Phan TKT, Shahbazzadeh F, Kihara T.
Alpha-mangostin reduces mechanical stiffness of various cells.
Hum. Cell
2020
PubMed ID: 32078151
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12092
Kamiya Y, Kikuchi T, Goto H, Okabe I, Takayanagi Y, Suzuki Y, Sawada N, Okabe T, Suzuki Y, Kondo S, Hayashi JI, Mitani A.
IL-35 and RANKL Synergistically Induce Osteoclastogenesis in RAW264 Mouse Monocytic Cells.
Int J Mol Sci
2020
PubMed ID: 32197293
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12110
Uchikawa M, Kato M, Nagata A, Sanada S, Yoshikawa Y, Tsunematsu Y, Sato M, Suzuki T, Hashidume T, Watanabe K, Yoshikawa Y, Miyoshi N.
Elevated levels of proinflammatory volatile metabolites in feces of high fat diet fed KK-Ay mice.
Sci Rep
2020
PubMed ID: 32231228
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12126
Amlabu WE, Antwi CA, Awandare G, Gwira TM.
Elucidating the possible mechanism of action of some pathogen box compounds against Leishmania donovani.
PLoS Negl Trop Dis
2020
PubMed ID: 32275665
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12130
Sanada S, Suzuki T, Nagata A, Hashidume T, Yoshikawa Y, Miyoshi N.
Intestinal microbial metabolite stercobilin involvement in the chronic inflammation of ob/ob mice.
Sci Rep
2020
PubMed ID: 32296105
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12171
Kazunori Sasaki, Yuri Inami, Kenichi Tominaga, Hideo Kigoshi, Takashi Arimura , and Hiroko Isoda
Synthesis of 2-(2-Hydroxyethoxy)-3-hydroxysqualene and Characterization of Its Anti-Inflammatory Effects
BioMed Research International
2020
PubMed ID: 32382581
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10948
Karen Yotsumoto, Terukazu Sanui, Urara Tanaka, Hiroaki Yamato, Rehab Alshargabi, Takanori Shinjo, Yuki Nakao, Yukari Watanabe, Chikako Hayashi, Takaharu Taketomi, Takao Fukuda, Fusanori Nishimura
Amelogenin Downregulates Interferon Gamma-Induced Major Histocompatibility Complex Class II Expression Through Suppression of Euchromatin Formation in the Class II Transactivator Promoter IV Region in Macrophages
Front Immunol
2020
11:709
PubMed ID: 32373130
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12488
Takeda Y, Murata T, Jamsransuren D, Suganuma K, Kazami Y, Batkhuu J, Badral D, Ogawa H.
Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Viruses Including SARS-CoV-2
Viruses
2020
12(7):699
PubMed ID: 32605306
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13012
Kumagai M, Nishikawa K, Mishima T, Yoshida I, Ide M, Watanabe A, Fujita K, Morimoto Y.
Fluorinated Kavalactone Inhibited RANKL-Induced Osteoclast Differentiation of RAW264 Cells.
Biol Pharm Bull
2020
PubMed ID: 32378565
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13036
Tanaka M, Sato A, Kishimoto Y, Mabashi-Asazuma H, Kondo K, Iida K.
Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes.
Nutrients
2020
PubMed ID: 32443660
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13065
Crentsil JA, Yamthe LRT, Anibea BZ, Broni E, Kwofie SK, Tetteh JKA, Osei-Safo D.
Leishmanicidal Potential of Hardwickiic Acid Isolated From Croton sylvaticus.
Front Pharmacol
2020
PubMed ID: 32523532
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13097
Kim Y, Wu L, Park HC, Yang HC.
Reduction of fibrous encapsulation by polyethylene glycol-grafted liposomes containing phosphatidylserine.
Biomed Mater
2020
PubMed ID: 32615550
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13137
Kawata R, Oda S, Koya Y, Kajiyama H, Yokoi T.
Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production.
Toxicology
2020
PubMed ID: 32739513
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13139
Kawai K, Egami Y, Nishigaki A, Araki N.
Rab35 Targeting to the Plasma Membrane Is Dependent on the C-terminal Polybasic Cluster.
Acta Histochem Cytochem
2020
PubMed ID: 32873993
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13146
Ertunc N, Sato C, Kitajima K.
Sialic acid sulfation is induced by the antibiotic treatment in mammalian cells.
Biosci Biotechnol Biochem
2020
PubMed ID: 32752946
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|
13150
Totani H, Shinjo K, Suzuki M, Katsushima K, Mase S, Masaki A, Ito A, Ri M, Kusumoto S, Komatsu H, Ishida T, Inagaki H, Iida S, Kondo Y.
Autocrine HGF/c-Met signaling pathway confers aggressiveness in lymph node adult T-cell leukemia/lymphoma.
Oncogene
2020
PubMed ID: 32747750
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|
13168
Mikami A, Ogita T, Namai F, Shigemori S, Sato T, Shimosato T.
Oral administration of Flavonifractor plautii attenuates inflammatory responses in obese adipose tissue.
Mol Biol Rep
2020
PubMed ID: 32808115
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13180
Wada S, Kanzaki H, Katsumata Y, Yamaguchi Y, Narimiya T, Attucks OC, Nakamura Y, Tomonari H.
Bach1 Inhibition Suppresses Osteoclastogenesis via Reduction of the Signaling via Reactive Oxygen Species by Reinforced Antioxidation.
Front Cell Dev Biol
2020
PubMed ID: 32850850
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13258
Takeuchi T, Horimoto Y, Oyama M, Nakatani S, Kobata K, Tamura M, Arata Y, Hatanaka T.
Osteoclast Differentiation Is Suppressed by Increased O-GlcNAcylation Due to Thiamet G Treatment.
Biol Pharm Bull
2020
PubMed ID: 32999159
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|
13294
Nishigaki C, Nakayama M, Miyata H.
Cell physiological responses of RAW264 macrophage cells to a 50-Hz magnetic field.
Int J Radiat Biol
2020
PubMed ID: 33052723
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13298
Yang X, Sasano T, Ebana Y, Takeuchi JK, Ihara K, Yamazoe M, Furukawa T.
Functional Role of the L396R Mutation of Tks5 Identified by an Exome-Wide Association Study in Atrial Fibrillation.
Circ J
2020
PubMed ID: 33087629
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13324
Yahiro K, Ogura K, Goto Y, Iyoda S, Kobayashi T, Takeuchi H, Ohnishi M, Moss J.
Subtilase cytotoxin induces a novel form of Lipocalin 2, which promotes Shiga-toxigenic Escherichia coli survival.
Sci Rep
2020
PubMed ID: 33144618
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13341
Matur M, Madhyastha H, Shruthi TS, Madhyastha R, Srinivas SP, Navya PN, Daima HK.
Engineering bioactive surfaces on nanoparticles and their biological interactions.
Sci Rep
2020
PubMed ID: 33184324
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13492
Masanori HASHIMOTO, Haruaki KITAGAWA, Yusuke TAKAHASHI, Mikako HAYASHI, Satoshi IMAZATO
Cytotoxicity of S-PRG Fillers: Direct Exposure of Fillers and Eluates from the Fillers to RAW264 Cells
Nano Biomedicine
2020
12:3-10
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13545
Quan H, Kim Y, Wu L, Park HC, Yang HC.
Modulation of Macrophage Polarization by Phospholipids on the Surface of Titanium
Molecules
2020
25(11):2700
PubMed ID: 32532146
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|
13614
Kuramoto M, Kawashima N, Tazawa K, Nara K, Fujii M, Noda S, Hashimoto K, Nozaki K, Okiji T.
Mineral trioxide aggregate suppresses pro-inflammatory cytokine expression via the calcineurin/nuclear factor of activated T cells/early growth response 2 pathway in lipopolysaccharide-stimulated macrophages
Int Endod J
2020
53(12):1653-1665
PubMed ID: 32767860
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13633
Lu DZ, Dong W, Feng XJ, Chen H, Liu JJ, Wang H, Zang LY, Qi MC.
CaMKII(δ) regulates osteoclastogenesis through ERK, JNK, and p38 MAPKs and CREB signalling pathway
Mol Cell Endocrinol
2020
508:110791
PubMed ID: 32173349
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13639
Nishiguchi A, Taguchi T.
Development of an immunosuppressive camouflage-coating platform with nanocellulose and cell membrane vesicles
J Biomater Sci Polym Ed
2020
31(15):1912-1924
PubMed ID: 32538290
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13643
Nishiguchi A, Taguchi T.
Sustained-immunostimulatory nanocellulose scaffold to enhance vaccine efficacy
J Biomed Mater Res A
2020
108(5):1159-1170
PubMed ID: 31990447
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13906
Ide M, Yoshida I, Kumagai M, Mishima T, Takahashi Y, Fujita K, Igarashi T, Matsuura E.
Tithonia diversifolia-derived orizabin suppresses cell adhesion, differentiation, and oxidized LDL accumulation by Akt signaling suppression via PTEN promotion in THP-1 cells
J Food Biochem
2020
44(7):e13268
PubMed ID: 32412116
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20264
Kawai K, Nishigaki A, Moriya S, Egami Y, Araki N.
Rab10-Positive Tubular Structures Represent a Novel Endocytic Pathway That Diverges From Canonical Macropinocytosis in RAW264 Macrophages.
Front Immunol
2020
12:649600
PubMed ID: 34135890
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20271
Takahashi F, Endo K, Matsui R, Yamamoto K, Tanaka S.
Brassica rapa L. activates macrophages via Toll-like receptors.
Biosci Biotechnol Biochem
2020
85(3):656-665
PubMed ID: 33589925
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15459
Koga M, Kanaoka Y, Okamoto M, Nakao Y, Inada K, Takayama S, Kataoka Y, Yamauchi A.
Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression
J Pharmacol Sci
2020
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Ii H, Imai T, Yaegaki K, Irie K, Ekuni D, Morita M.
Oral malodorous compound induces osteoclast differentiation without receptor activator of nuclear factor κB ligand
J Periodontol
2020
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Chaweewannakorn W, Ariyoshi W, Okinaga T, Fujita Y, Maki K, Nishihara T.
Ameloblastin attenuates RANKL-mediated osteoclastogenesis by suppressing activation of nuclear factor of activated T-cell cytoplasmic 1 (NFATc1).
J. Cell. Physiol.
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Madhyastha R, Madhyastha H, Pengjam Y, Nurrahmah QI, Nakajima Y, Maruyama M.
The pivotal role of microRNA-21 in osteoclastogenesis inhibition by anthracycline glycoside aloin.
J Nat Med
2019
73(1):59-66
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11279
Sun S, Li K, Xiao L, Lei Z, Zhang Z.
Characterization of polysaccharide from Helicteres angustifolia L. and its immunomodulatory activities on macrophages RAW264.7.
Biomed. Pharmacother.
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Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Ando K, Tanimoto K.
The effect of mesenchymal stem cells on osteoclast precursor cell differentiation.
J Oral Sci
2019
PubMed ID: 30541990
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Islam Z, Inui T, Ishibashi O.
Gpr137b is an orphan G-protein-coupled receptor associated with M2 macrophage polarization.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 30595385
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11380
Nemoto R, Fujieda K, Hiruta Y, Hishida M, Ayano E, Maitani Y, Nagase K, Kanazawa H.
Liposomes with temperature-responsive reversible surface properties.
Colloids Surf B Biointerfaces
2019
PubMed ID: 30641302
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Yoshinaga N, Uchida S, Naito M, Osada K, Cabral H, Kataoka K.
Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection.
Biomaterials
2019
PubMed ID: 30669016
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Manabe Y, Hirata T, Sugawara T.
Inhibitory Effect of Carotenoids on Ligand-induced Lipid Raft Translocation of Immunoreceptors.
J Oleo Sci
2019
PubMed ID: 30651415
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11389
Wang W, Nakashima KI, Hirai T, Inoue M.
Anti-inflammatory effects of naturally occurring retinoid X receptor agonists isolated from Sophora tonkinensis Gagnep. via retinoid X receptor/liver X receptor heterodimers.
J Nat Med
2019
PubMed ID: 30656541
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11457
Takahashi S, Yoshida M, Watanabe MM, Isoda H.
Anti-Inflammatory Effects of Aurantiochytrium limacinum 4W-1b Ethanol Extract on Murine Macrophage RAW264 Cells.
Biomed Res Int
2019
PubMed ID: 30809537
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11437
Yanagihara Y, Inoue K, Saeki N, Sawada Y, Yoshida S, Lee J, Iimura T, Imai Y.
Zscan10 suppresses osteoclast differentiation by regulating expression of Haptoglobin.
Bone
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PubMed ID: 30771488
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11454
Antwi CA, Amisigo CM, Adjimani JP, Gwira TM.
In vitro activity and mode of action of phenolic compounds on Leishmania donovani.
PLoS Negl Trop Dis
2019
PubMed ID: 30802252
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11477
Zhang T, Ono K, Tsutsuki H, Ihara H, Islam W, Akaike T, Sawa T.
Enhanced Cellular Polysulfides Negatively Regulate TLR4 Signaling and Mitigate Lethal Endotoxin Shock.
Cell Chem Biol
2019
PubMed ID: 30853417
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5357
Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.
AUTACs: Cargo-Specific Degraders Using Selective Autophagy.
Mol Cell
2019
76(5):797-810
PubMed ID: 31606272
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11498
Narita Y, Shimizu K, Ikemoto K, Uchino R, Kosugi M, Maess MB, Magata Y, Oku N, Ogawa M.
Macrophage-targeted, enzyme-triggered fluorescence switch-on system for detection of embolism-vulnerable atherosclerotic plaques.
J Control Release
2019
PubMed ID: 30936020
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11508
Saito H, Tanaka T, Sugahara M, Tanaka S, Fukui K, Wakashima T, Nangaku M.
Inhibition of prolyl hydroxylase domain (PHD) by JTZ-951 reduces obesity-related diseases in the liver, white adipose tissue, and kidney in mice with a high-fat diet.
Lab. Invest.
2019
PubMed ID: 30952940
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11539
Suzuka H, Mimura A, Inaoka Y, Murase K.
Magnetic Nanoparticles in Macrophages and Cancer Cells Exhibit Different Signal Behavior on Magnetic Particle Imaging.
J Nanosci Nanotechnol
2019
PubMed ID: 31039837
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11604
Miyazaki Y, Iwaihara Y, Bak J, Nakano H, Takeuchi S, Takeuchi H, Matsui T, Tachikawa D.
The cooperative induction of macrophage activation by fucoidan derived from Cladosiphon okamuranus and β-glucan derived from Saccharomyces cerevisiae.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 31221482
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11617
Takeuchi T, Koinuma S, Yokosawa H, Arata Y.
An Approach for the Identification of Proteins Modified with ISG15.
Methods Mol. Biol.
2019
PubMed ID: 31256383
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11736
Wang X, Batubara I, Yamauchi K, Mitsunaga T.
Identification and structure-activity relationship (SAR) of chemical constituents from Daemonorops draco (Willd.) Blume and selected commercial flavonoids on anti-osteoclastogenesis activity.
Fitoterapia
2019
PubMed ID: 31376421
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11772
Okuda-Hanafusa C, Uchio R, Fuwa A, Kawasaki K, Muroyama K, Yamamoto Y, Murosaki S.
Turmeronol A and turmeronol B from Curcuma longa prevent inflammatory mediator production by lipopolysaccharide-stimulated RAW264.7 macrophages, partially via reduced NF-κB signaling.
Food Funct
2019
PubMed ID: 31454011
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11780
Tan H, Zhao C, Zhu Q, Katakura Y, Tanaka H, Ohnuki K, Shimizu K.
Ursolic Acid Isolated from the Leaves of Loquat ( Eriobotrya japonica) Inhibited Osteoclast Differentiation through Targeting Exportin 5.
J. Agric. Food Chem.
2019
PubMed ID: 30827108
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11793
Mizuno Y, Taguchi T.
Growth factor-free, angiogenic hydrogel based on hydrophobically modified Alaska pollock gelatin.
J Tissue Eng Regen Med
2019
PubMed ID: 31503405
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11801
Ueta M, Takaoka K, Yamamura M, Maeda H, Tamaoka J, Nakano Y, Noguchi K, Kishimoto H.
Effects of TGF‑β1 on the migration and morphology of RAW264.7 cells in vitro.
Mol Med Rep
2019
PubMed ID: 31545488
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Ara T, Koide M, Kitamura H, Sogawa N.
Effects of shokyo (Zingiberis Rhizoma) and kankyo (Zingiberis Processum Rhizoma) on prostaglandin E2 production in lipopolysaccharide-treated mouse macrophage RAW264.7 cells.
PeerJ
2019
PubMed ID: 31576251
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11873
Ju N, Shimamura M, Hayashi H, Ikeda Y, Yoshida S, Nakamura A, Morishita R, Rakugi H, Nakagami H.
Preventative effects of the partial RANKL peptide MHP1-AcN in a mouse model of imiquimod-induced psoriasis.
Sci Rep
2019
PubMed ID: 31659208
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6944
Yo S, Hamamura K, Mishima Y, Hamajima K, Mori H, Furukawa K, Kondo H, Tanaka K, Sato T, Miyazawa K, Goto S, Togari A.
Deficiency of GD3 Synthase in Mice Resulting in the Attenuation of Bone Loss with Aging.
Int J Mol Sci
2019
20(11):2825
PubMed ID: 31185614
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9468
Kazuyo Fujita, Masaharu Somiya, Shun'ichi Kuroda, Shuji Hinuma
Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes
Biochem Biophys Res Commun
2019
510(1):184-190
PubMed ID: 30678809
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10512
Sayumi Yamada et al
Anti-Inflammatory and Antimicrobial Activities of Aqueous Extracts of Wild Mushrooms from Japan
International Journal of Medicinal Mushrooms
2019
21:469-486
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10763
Ahmed Elkhateeb, Mona El-Shabrawy, Rehab F. Abdel-Rahman, Mona M. Marzouk, Ahmed H. El-Desoky, El-Sayed S. Abdel-Hameed & Sameh R. Hussein
LC-MS-based metabolomic profiling of Lepidium coronopus water extract, anti-inflammatory and analgesic activities, and chemosystematic significance
Medicinal Chemistry Research
2019
28:505–514
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10848
X.YangaZ.Lei, Y.YuaL.Xiao, D.Cheng, Z.Zhang
Phytochemical characteristics of callus suspension culture of Helicteres angustifolia L. and its in vitro antioxidant, antidiabetic and immunomodulatory activities
South African Journal of Botany
2019
121:178-185
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11886
Ali MFZ, Ohta T, Ido A, Miura C, Miura T.
The Dipterose of Black Soldier Fly (Hermetia illucens) Induces Innate Immune Response through Toll-Like Receptor Pathway in Mouse Macrophage RAW264.7 Cells.
Biomolecules
2019
PubMed ID: 31683715
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Pavillon N, Smith NI.
Immune cell type, cell activation, and single cell heterogeneity revealed by label-free optical methods.
Sci Rep
2019
PubMed ID: 31745140
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11914
Shimakura H, Gen-Nagata F, Haritani M, Furusaki K, Kato Y, Yamashita-Kawanishi N, LE DT, Tsuzuki M, Tohya Y, Kyuwa S, Saito H, Horimoto T, Onodera T, Haga T.
Inactivation of human norovirus and its surrogate by the disinfectant consisting of calcium hydrogen carbonate mesoscopic crystals.
FEMS Microbiol. Lett.
2019
PubMed ID: 31758686
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11948
Yamashiro T, Yasujima T, Ohta K, Inoue K, Yuasa H.
Identification of the amino acid residue responsible for the myricetin sensitivity of human proton-coupled folate transporter.
Sci Rep
2019
PubMed ID: 31792273
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12316
Kitazawa R, Kinto-Shibahara S, Haraguchi R, Kohara Y, Kitazawa S.
Activation of protein kinase C accelerates murine osteoclastogenesis partly via transactivation of RANK gene through functional AP-1 responsive element in RANK gene promoter
Biochem Biophys Res Commun
2019
515(2):268-274
PubMed ID: 31146918
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Sakakura A, Pauze M, Namiki A, Funakoshi-Tago M, Tamura H, Hanaya K, Higashibayashi S, Sugai T.
Chemoenzymatic synthesis of hydroxytyrosol monoesters and their suppression effect on nitric oxide production stimulated by lipopolysaccharides
Biosci Biotechnol Biochem
2019
83(2):185-191
PubMed ID: 30319060
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12555
Islam Z, Horikawa A, Inui T, Ishibashi O.
Datasets of microarray analysis to identify Gpr137b-dependent interleukin-4-responsive genes in the mouse macrophage cell line RAW264
Data Brief
2019
23:103669
PubMed ID: 31372377
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Saiki P, Kawano Y, Nakajima Y, Van Griensven LJLD, Miyazaki K.
Reporters Derived from RAW 264.7 for Anti-Inflammation Screening of Natural Products
Int J Mol Sci
2019
20(18):4620
PubMed ID: 31540402
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12557
Kono Y, Gogatsubo S, Ohba T, Fujita T.
Enhanced macrophage delivery to the colon using magnetic lipoplexes with a magnetic field
Drug Deliv
2019
26(1):935-943
PubMed ID: 31530198
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12559
Li F, Kitajima S, Kohno S, Yoshida A, Tange S, Sasaki S, Okada N, Nishimoto Y, Muranaka H, Nagatani N, Suzuki M, Masuda S, Thai TC, Nishiuchi T, Tanaka T, Barbie DA, Mukaida N, Takahashi C.
Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion
Cancer Res
2019
79(15):3903-3915
PubMed ID: 31189648
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12978
Kojima C, Narita Y, Nakajima Y, Morimoto N, Yoshikawa T, Takahashi N, Handa A, Waku T, Tanaka N.
Modulation of Cell Adhesion and Differentiation on Collagen Gels by the Addition of the Ovalbumin Secretory Signal Peptide.
ACS Biomater Sci Eng
2019
PubMed ID: 33405701
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15292
Nagata J, Yokodera H, Maeda G.
In Vitro and in Vivo Studies on Anti-Inflammatory Effects of Traditional Okinawan Vegetable Methanol Extracts
ACS Omega
2019
4(13):15660-15664
PubMed ID: 31572868
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Fujihara Y, Hikita A, Takato T, Hoshi K.
Roles of macrophage migration inhibitory factor in cartilage tissue engineering.
J. Cell. Physiol.
2018
233:1490-1499
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10432
Tokuyama-Nakai S, Kimura H, Ishihara T, Jisaka M, Yokota K.
In Vitro Anti-inflammatory and Antioxidant Activities of 3,5,4'-Trihydroxy-6,7-Methylenedioxyflavone-O-Glycosides and Their Aglycone from Leaves of Polygonum tinctorium Lour.
Appl. Biochem. Biotechnol.
2018
184:414-431
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10557
Elfeky M, Yoneshiro T, Okamatsu-Ogura Y, Kimura K.
Adiponectin suppression of late inflammatory mediator, HMGB1-induced cytokine expression in RAW264 macrophage cells.
J. Biochem.
2018
163:143-153
PubMed ID: 29048484
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10569
Yamaguchi Y, Kanzaki H, Katsumata Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.
Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation.
J. Cell. Mol. Med.
2018
22:1138-1147
PubMed ID: 29063666
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10614
Stockler-Pinto MB, Soulage CO, Borges NA, Cardozo LFMF, Dolenga CJ, Nakao LS, Pecoits-Filho R, Fouque D, Mafra D.
From bench to the hemodialysis clinic: protein-bound uremic toxins modulate NF-κB/Nrf2 expression.
Int Urol Nephrol
2018
50:347-354
PubMed ID: 29151180
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10645
Nagahara H, Seno T, Yamamoto A, Obayashi H, Inoue T, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y.
Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.
Biochem. Biophys. Res. Commun.
2018
495:1901-1907
PubMed ID: 29225172
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10696
Kumagai M, Watanabe A, Yoshida I, Mishima T, Nakamura M, Nishikawa K, Morimoto Y.
Evaluation of Aculeatin and Toddaculin Isolated from Toddalia asiatica as Anti-inflammatory Agents in LPS-Stimulated RAW264 Macrophages.
Biol. Pharm. Bull.
2018
41:132-137
PubMed ID: 29311475
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10708
Kon R, Tsubota Y, Minami M, Kato S, Matsunaga Y, Kimura H, Murakami Y, Fujikawa T, Sakurai R, Tomimoto R, Machida Y, Ikarashi N, Sugiyama K.
CPT-11-Induced Delayed Diarrhea Develops via Reduced Aquaporin-3 Expression in the Colon.
Int J Mol Sci
2018
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PubMed ID: 29316651
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10711
Egami Y, Araki N.
Transient recruitment of M-Ras GTPase to phagocytic cups in RAW264 macrophages during FcγR-mediated phagocytosis.
Microscopy (Oxf)
2018
67:68-74
PubMed ID: 29340604
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10714
Tsukayama I, Toda K, Takeda Y, Mega T, Tanaka M, Kawakami Y, Takahashi Y, Kimoto M, Yamamoto K, Miki Y, Murakami M, Suzuki-Yamamoto T.
Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway.
J Clin Biochem Nutr
2018
62:139-147
PubMed ID: 29610553
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10782
Miyashita T, Minami K, Ito M, Koizumi R, Sagane Y, Watanabe T, Niwa K.
Emu Oil Reduces LPS-Induced Production of Nitric Oxide and TNF-α but not Phagocytosis in RAW 264 Macrophages.
J Oleo Sci
2018
67:471-477
PubMed ID: 29526880
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10790
El-Desoky AH, Abdel-Rahman RF, Ahmed OK, El-Beltagi HS, Hattori M.
Anti-inflammatory and antioxidant activities of naringin isolated from Carissa carandas L.: In vitro and in vivo evidence.
Phytomedicine
2018
42:126-134
PubMed ID: 29655678
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10799
Kawai C, Yamauchi A, Kuribayashi F.
Monoclonal antibody 7D5 recognizes the R147 epitope on the gp91phox , phagocyte flavocytochrome b558 large subunit.
Microbiol. Immunol.
2018
62:269-280
PubMed ID: 29573449
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11027
Miyake T, Miyake T, Sakaguchi M, Nankai H, Nakazawa T, Morishita R.
Prevention of Asthma Exacerbation in a Mouse Model by Simultaneous Inhibition of NF-kB and STAT6 Activation Using a Chimeric Decoy Strategy
Mol Ther Nucleic Acids
2018
10:159-169
PubMed ID: 29499930
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11198
Ikebuchi Y, Aoki S, Honma M, Hayashi M, Sugamori Y, Khan M, Kariya Y, Kato G, Tabata Y, Penninger JM, Udagawa N, Aoki K, Suzuki H.
Coupling of bone resorption and formation by RANKL reverse signalling.
Nature
2018
561(7722):195-200
PubMed ID: 30185903
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Mukai Y, Yamanishi R.
Retinol but not retinoic acid can enhance the glutathione level, in a manner similar to β-carotene, in a murine cultured macrophage cell line.
Food Sci Nutr
2018
PubMed ID: 30258608
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11098
Ali MFZ, Yasin IA, Ohta T, Hashizume A, Ido A, Takahashi T, Miura C, Miura T.
The silkrose of Bombyx mori effectively prevents vibriosis in penaeid prawns via the activation of innate immunity.
Sci Rep
2018
8(1):8836
PubMed ID: 29892000
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11116
Tasaka T, Kuwada E, Izuchi Y, Nishigawa R, Yamada H, Unuma H, Tokunaga K, Hayakawa A, Go A, Go K, Uto Y.
Concentration-dependent Activation of Inflammatory/Anti-inflammatory Functions of Macrophages by Hydrolyzed Whey Protein.
Anticancer Res.
2018
38(7):4299-4304
PubMed ID: 29970565
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11122
Sakoda M, Kaneko M, Ohta S, Qi P, Ichimura S, Yatomi Y, Ito T.
Injectable Hemostat Composed of a Polyphosphate-Conjugated Hyaluronan Hydrogel.
Biomacromolecules
2018
19(8):3280-3290
PubMed ID: 29985587
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11186
Kawasaki K, Okuda-Hanafusa C, Aoyagi M, Taoka K, Yamamoto N, Muroyama K, Murosaki S, Yamamoto Y.
Inhibitory effect of the compounds from the water extract of Curcuma longa on the production of PGE2 and NO in a macrophage cell line stimulated by LPS.
Biosci. Biotechnol. Biochem.
2018
82(12):2109-2117
PubMed ID: 30146952
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11200
Odkhuu E, Komatsu T, Koide N, Naiki Y, Takeuchi K, Tanaka Y, Tsolmongyn B, Jambalganiin U, Morita N, Yoshida T, Gotoh B, Yokochi T.
Sendai virus C protein limits NO production in infected RAW264.7 macrophages.
Innate Immun
2018
24(7):430-438
PubMed ID: 30189760
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11074
Tsukamoto H, Takeuchi S, Kubota K, Kobayashi Y, Kozakai S, Ukai I, Shichiku A, Okubo M, Numasaki M, Kanemitsu Y, Matsumoto Y, Nochi T, Watanabe K, Aso H, Tomioka Y.
Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKK?-IRF3 axis activation.
J. Biol. Chem.
2018
293(26):10186-10201
PubMed ID: 29760187
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11112
Niino T, Tago K, Yasuda D, Takahashi K, Mashino T, Tamura H, Funakoshi-Tago M.
A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis.
Biochem. Pharmacol.
2018
155:182-197
PubMed ID: 29940171
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11249
Kamiya T, Tanimoto Y, Fujii N, Negishi T, Suzuki T, Hatano T, Arimoto-Kobayashi S.
2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae.
Food Chem. Toxicol.
2018
PubMed ID: 30316843
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11493
Katsumata Y, Kanzaki H, Honda Y, Tanaka T, Yamaguchi Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.
Single Local Injection of Epigallocatechin Gallate-Modified Gelatin Attenuates Bone Resorption and Orthodontic Tooth Movement in Mice.
Polymers (Basel)
2018
10(12)
PubMed ID: 30961309
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11349
Sugiyama Y, Hiraiwa Y, Hagiya Y, Nakajima M, Tanaka T, Ogura SI.
5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW 264.7 macrophages.
BMC Immunol.
2018
PubMed ID: 30567499
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4441
Seisho Azuma, Yoshinobu Murakami, Eiko Azuma, Kimiye Baba, Masahiko Taniguchi
Anti-inflammatory effects of flavonoids in Citrus jabara fruit peels
Trends in Immunotherapy
2018
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Quan H, Kim Y, Park HC, Yang HC.
Effects of phosphatidylserine-containing supported lipid bilayers on the polarization of macrophages.
J Biomed Mater Res A
2018
PubMed ID: 29781181
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4325
Hoshi K, Yamazaki T, Yoshikawa C, Tsugawa W, Ikebukuro K, Sode K.
Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production.
Int J Nanomedicine
2018
PubMed ID: 30122920
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4326
Saiki P, Nakajima Y, Van Griensven LJLD, Miyazaki K.
Real-time monitoring of IL-6 and IL-10 reporter expression for anti-inflammation activity in live RAW 264.7 cells.
Biochem. Biophys. Res. Commun.
2018
PubMed ID: 30301531
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4327
Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Tanimoto K.
Dynamic imaging of the effect of mesenchymal stem cells on osteoclast precursor cell chemotaxis for bone defects in the mouse skull.
J Dent Sci
2018
PubMed ID: 30895145
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4328
Sumi K, Abe T, Kunimatsu R, Oki N, Tsuka Y, Awada T, Nakajima K, Ando K, Tanimoto K.
The effect of mesenchymal stem cells on chemotaxis of osteoclast precursor cells.
J Oral Sci
2018
PubMed ID: 29925706
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4329
Kajita T, Ariyoshi W, Okinaga T, Mitsugi S, Tominaga K, Nishihara T.
Mechanisms involved in enhancement of osteoclast formation by activin-A.
J. Cell. Biochem.
2018
PubMed ID: 29737562
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4330
Sakamoto T, Ohashi W, Tomita K, Hattori K, Matsuda N, Hattori Y.
Anti-inflammatory properties of cilostazol: Its interruption of DNA binding activity of NF-κB from the Toll-like receptor signaling pathways.
Int. Immunopharmacol.
2018
PubMed ID: 30005227
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4331
El-Beih AA, El-Desoky AH, Al-Hammady MA, Elshamy AI, Hegazy MF, Kato H, Tsukamoto S.
New inhibitors of RANKL-induced Osteoclastogenesis from the marine sponge Siphonochalina siphonella.
Fitoterapia
2018
PubMed ID: 29729401
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4332
Tanaka M, Kishimoto Y, Sasaki M, Sato A, Kamiya T, Kondo K, Iida K.
Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways.
Oxid Med Cell Longev
2018
PubMed ID: 30533177
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4333
Kawabata K, Baba N, Sakano T, Hamano Y, Taira S, Tamura A, Baba S, Natsume M, Ishii T, Murakami S, Ohigashi H.
Functional properties of anti-inflammatory substances from quercetin-treated Bifidobacterium adolescentis.
Biosci. Biotechnol. Biochem.
2018
PubMed ID: 29165050
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4334
Fukai E, Sato H, Watanabe M, Nakae D, Totsuka Y.
Establishment of an in vivo simulating co-culture assay platform for genotoxicity of multi-walled carbon nanotubes.
Cancer Sci.
2018
PubMed ID: 29444368
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4335
Hussain Z, Uyama T, Kawai K, Binte Mustafiz SS, Tsuboi K, Araki N, Ueda N.
Phosphatidylserine-stimulated production of N-acyl-phosphatidylethanolamines by Ca2+-dependent N-acyltransferase.
Biochim Biophys Acta Mol Cell Biol Lipids
2018
PubMed ID: 29447909
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4336
Takahashi S, Sakamaki M, Ferdousi F, Yoshida M, Demura M, Watanabe MM, Isoda H.
Ethanol Extract of Aurantiochytrium mangrovei 18W-13a Strain Possesses Anti-inflammatory Effects on Murine Macrophage RAW264 Cells.
Front Physiol
2018
PubMed ID: 30319432
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4496
Su YW, Chim SM, Zhou L, Hassanshahi M, Chung R, Fan C, Song Y, Foster BK, Prestidge CA, Peymanfar Y, Tang Q, Butler LM, Gronthos S, Chen D, Xie Y, Chen L, Zhou XF, Xu J, Xian CJ.
Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats.
Bone
2018
116:232-247
PubMed ID: 30125729
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4497
Kuroda C, Ueda K, Haniu H, Ishida H, Okano S, Takizawa T, Sobajima A, Kamanaka T, Yoshida K, Okamoto M, Tsukahara T, Matsuda Y, Aoki K, Kato H, Saito N.
Different aggregation and shape characteristics of carbon materials affect biological responses in RAW264 cells.
Int J Nanomedicine
2018
13:6079-6088
PubMed ID: 30323595
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4498
Momozane T, Kawamura T, Itoh Y, Sanosaka M, Sasaki T, Kanzaki R, Ose N, Funaki S, Shintani Y, Minami M, Okumura M, Takemori H.
Carnosol suppresses interleukin-6 production in mouse lungs injured by ischemia-reperfusion operation and in RAW264.7 macrophages treated with lipopolysaccharide.
Biochem. Cell Biol.
2018
96(6):769-776
PubMed ID: 29958095
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4499
Choodej S, Pudhom K, Mitsunaga T.
Inhibition of TNF-α-Induced Inflammation by Sesquiterpene Lactones from Saussurea lappa and Semi-Synthetic Analogues.
Planta Med.
2018
84(5):329-335
PubMed ID: 28962049
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14915
Komatsu W, Kishi H, Yagasaki K, Ohhira S.
Urolithin A attenuates pro-inflammatory mediator production by suppressing PI3-K/Akt/NF-κB and JNK/AP-1 signaling pathways in lipopolysaccharide-stimulated RAW264 macrophages: Possible involvement of NADPH oxidase-derived reactive oxygen species
Eur J Pharmacol
2018
833:411-424
PubMed ID: 29932926
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15294
Pavillon N, Hobro AJ, Akira S, Smith NI.
Noninvasive detection of macrophage activation with single-cell resolution through machine learning
Proc Natl Acad Sci U S A
2018
115(12):E2676-E2685
PubMed ID: 29511099
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7036
Komiya C, Tanaka M, Tsuchiya K, Shimazu N, Mori K, Furuke S, Miyachi Y, Shiba K, Yamaguchi S, Ikeda K, Ochi K, Nakabayashi K, Hata KI, Itoh M, Suganami T, Ogawa Y.
Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis.
Sci Rep
2017
7:44754
PubMed ID: 28303974
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9723
Iwazaki K, Tanaka T, Hozumi Y, Okada M, Tsuchiya R, Iseki K, Topham MK, Kawamae K, Takagi M, Goto K.
DGKζ Downregulation Enhances Osteoclast Differentiation and Bone Resorption Activity Under Inflammatory Conditions.
J. Cell. Physiol.
2017
232:617-624
PubMed ID: 27312515
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9944
Kanzaki H, Shinohara F, Itohiya K, Yamaguchi Y, Katsumata Y, Matsuzawa M, Fukaya S, Miyamoto Y, Wada S, Nakamura Y.
RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice.
FASEB J.
2017
31:781-792
PubMed ID: 27836987
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9964
Shirasugi M, Nishioka K, Yamamoto T, Nakaya T, Kanamura N.
Normal human gingival fibroblasts undergo cytostasis and apoptosis after long-term exposure to butyric acid.
Biochem. Biophys. Res. Commun.
2017
482:1122-1128
PubMed ID: 27914813
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10001
Quan H, Park HC, Kim Y, Yang HC.
Modulation of the anti-inflammatory effects of phosphatidylserine-containing liposomes by PEGylation.
J Biomed Mater Res A
2017
105:1479-1486
PubMed ID: 27998010
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10074
Takano A, Fukuda T, Shinjo T, Iwashita M, Matsuzaki E, Yamamichi K, Takeshita M, Sanui T, Nishimura F.
Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation.
Metab. Clin. Exp.
2017
69:157-170
PubMed ID: 28285646
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10085
Ariyoshi W, Okinaga T, Chaweewannakorn W, Akifusa S, Nisihara T.
Mechanisms involved in enhancement of matrix metalloproteinase-9 expression in macrophages by interleukin-33.
J. Cell. Physiol.
2017
232:3481-3495
PubMed ID: 28105703
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10122
Taniguchi M, Ochiai A, Toyoda R, Sato T, Saitoh E, Kato T, Tanaka T.
Effects of arginine and leucine substitutions on anti-endotoxic activities and mechanisms of action of cationic and amphipathic antimicrobial octadecapeptide from rice α-amylase.
J. Pept. Sci.
2017
23:252-260
PubMed ID: 28185358
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10165
Takeuchi T, Sugimoto A, Imazato N, Tamura M, Nakatani S, Kobata K, Arata Y.
Glucosamine Suppresses Osteoclast Differentiation through the Modulation of Glycosylation Including O-GlcNAcylation.
Biol. Pharm. Bull.
2017
40:352-356
PubMed ID: 28250278
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10169
Zhang J, Hiromoto S, Yamazaki T, Huang H, Jia G, Li H, Yuan G.
Macrophage phagocytosis of biomedical Mg alloy degradation products prepared by electrochemical method.
Mater Sci Eng C Mater Biol Appl
2017
75:1178-1183
PubMed ID: 28415404
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10190
Ichimura K, Shimizu T, Matsumoto A, Hirai S, Yokoyama E, Takeuchi H, Yahiro K, Noda M.
Nitric oxide-enhanced Shiga toxin production was regulated by Fur and RecA in enterohemorrhagic Escherichia coli O157.
Microbiologyopen
2017
6:
PubMed ID: 28294553
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10215
Yamagata Y, Tomioka H, Sakamoto K, Sato K, Harada H, Ikeda T, Kayamori K.
CD163-Positive Macrophages Within the Tumor Stroma Are Associated With Lymphangiogenesis and Lymph Node Metastasis in Oral Squamous Cell Carcinoma.
J. Oral Maxillofac. Surg.
2017
75:2144-2153
PubMed ID: 28399391
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10230
Hashiguchi A, Hitachi K, Zhu W, Tian J, Tsuchida K, Komatsu S.
Mung bean (Vigna radiata (L.)) coat extract modulates macrophage functions to enhance antigen presentation: A proteomic study.
J Proteomics
2017
161:26-37
PubMed ID: 28373035
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10285
Fereig RM, Kuroda Y, Terkawi MA, Mahmoud ME, Nishikawa Y.
Immunization with Toxoplasma gondii peroxiredoxin 1 induces protective immunity against toxoplasmosis in mice.
PLoS ONE
2017
12:e0176324
PubMed ID: 28448521
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10288
Kato T, Toyooka T, Ibuki Y, Masuda S, Watanabe M, Totsuka Y.
Effect of physicochemical character differences on the genotoxic potency of kaolin.
Genes Environ
2017
39:12
PubMed ID: 28469735
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10335
Wu S, Yano S, Chen J, Hisanaga A, Sakao K, He X, He J, Hou DX.
Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-Induced Inflammation through Dual Modulation of Inflammatory and Antioxidant Mediators.
J. Agric. Food Chem.
2017
65:5133-5141
PubMed ID: 28573848
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10380
Murata K, Motomura Y, Tanaka T, Kanno S, Yano T, Onimaru M, Shimoyama A, Nishio H, Sakai Y, Oh-Hora M, Hara H, Fukase K, Takada H, Masuda S, Ohga S, Yamasaki S, Hara T.
Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease.
Clin. Exp. Immunol.
2017
190:54-67
PubMed ID: 28640392
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10551
Saiki P, Kawano Y, Van Griensven LJLD, Miyazaki K.
The anti-inflammatory effect of Agaricus brasiliensis is partly due to its linoleic acid content.
Food Funct
2017
8:4150-4158
PubMed ID: 29022634
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10704
Hanagata N, Li X, Chen MH, Li J, Hattori S.
Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities.
Int J Nanomedicine
2017
13:43-62
PubMed ID: 29317815
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10915
Effect of Particle Size of Gold Nanoparticles on Matrix Metalloprotease Inhibition, Cytotoxicity and Genotoxicity
Journal of Biomaterials and Tissue Engineering,
2017
7, 139-146
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10949
Effect of 50-Hz Sinusoidal Magnetic Field on the Production of Superoxide Anion and the Expression of Heat-shock Protein 70 in RAW264 Cells
International Journal of Chemistry
2017
9
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4526
Yusuke Hiraku, Yoshihiro Nishikawa, Ning Ma, Tahmina Afroza, Kosuke Mizobuchi, Ryo Ishiyama, Yuta Matsunaga, Takamichi Ichinose, Shosuke Kawanishi, Mariko Murata
Nitrative DNA damage induced by carbon-black nanoparticles in macrophages and lung epithelial cells
Mutation Research/Genetic Toxicology and Environmental Mutagenesis
2017
818, 7-16
PubMed ID: 28477879
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6471
Horigome S, Yoshida I, Ito S, Inohana S, Fushimi K, Nagai T, Yamaguchi A, Fujita K, Satoyama T, Katsuda SI, Suzuki S, Watai M, Hirose N, Mitsue T, Shirakawa H, Komai M.
Inhibitory effects of Kaempferia parviflora extract on monocyte adhesion and cellular reactive oxygen species production in human umbilical vein endothelial cells.
Eur J Nutr
2017
56(3):949-964
PubMed ID: 26704713
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9460
Nan Ma, Di Yang, Hirohiko Okamura, Jumpei Teramachi, Tomokazu Hasegawa, Lihong Qiu, Tatsuji Haneji
Involvement of interleukin‑23 Induced by Porphyromonas Endodontalis Lipopolysaccharide in Osteoclastogenesis
Mol Med Rep
2017
15(2):559-566
PubMed ID: 28000855
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10050
Ha-Eun Yang, Yongjia Li, Akira Nishimura, Huei-Fen Jheng, Ana Yuliana, Ryuji Kitano-Ohue, Wataru Nomura, Nobuyuki Takahashi, Chu-Sook Kim, Rina Yu, Nahoko Kitamura, Si-Bum Park, Shigenobu Kishino, Jun Ogawa, Teruo Kawada, Tsuyoshi Goto
Synthesized Enone Fatty Acids Resembling Metabolites From Gut Microbiota Suppress Macrophage-Mediated Inflammation in Adipocytes
Mol Nutr Food Res
2017
Oct;61(10)
PubMed ID: 28544341
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10076
Yusuke Kono, Taketo Nakai, Hitomi Taguchi, Takuya Fujita
Development of Magnetic Anionic Liposome/Atelocollagen Complexes for Efficient Magnetic Drug Targeting
Drug Deliv
2017
24(1):1740-1749
PubMed ID: 29141461
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12320
Masayori Hagimori, Eri Hatabe, Kohei Sano, Hirotaka Miyazaki, Hitoshi Sasaki, Hideo Saji, Takahiro Mukai
An Activatable Fluorescent γ-Polyglutamic Acid Complex for Sentinel Lymph Node Imaging
Biol Pharm Bull
2017
40(3):297-302
PubMed ID: 28250270
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14213
Into T, Horie T, Inomata M, Gohda J, Inoue JI, Murakami Y, Niida S.
Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88
Sci Rep
2017
7(1):1009
PubMed ID: 28432355
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14216
Horiuchi T, Sakata N, Narumi Y, Kimura T, Hayashi T, Nagano K, Liu K, Nishibori M, Tsukita S, Yamada T, Katagiri H, Shirakawa R, Horiuchi H.
Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity
J Biol Chem
2017
292(20):8436-8446
PubMed ID: 28373282
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14220
Wang J, Ayano E, Maitani Y, Kanazawa H.
Tunable Surface Properties of Temperature-Responsive Polymer-Modified Liposomes Induce Faster Cellular Uptake
ACS Omega
2017
;2(1):316-325
PubMed ID: 31457232
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14255
Komatsu W, Itoh K, Akutsu S, Kishi H, Ohhira S.
Nasunin inhibits the lipopolysaccharide-induced pro-inflammatory mediator production in RAW264 mouse macrophages by suppressing ROS-mediated activation of PI3 K/Akt/NF-κB and p38 signaling pathways
Biosci Biotechnol Biochem
2017
1956-1966
PubMed ID: 28812425
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14379
Okabe I, Kikuchi T, Mogi M, Takeda H, Aino M, Kamiya Y, Fujimura T, Goto H, Okada K, Hasegawa Y, Noguchi T, Mitani A.
IL-15 and RANKL Play a Synergistically Important Role in Osteoclastogenesis
J Cell Biochem
2017
118(4):739-747
PubMed ID: 27608420
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14456
Yokota S, Chosa N, Kyakumoto S, Kimura H, Ibi M, Kamo M, Satoh K, Ishisaki A.
ROCK/actin/MRTF signaling promotes the fibrogenic phenotype of fibroblast-like synoviocytes derived from the temporomandibular joint
Int J Mol Med
2017
39(4):799-808
PubMed ID: 28259960
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14479
Nishina A, Shimizu K, Koketsu M, Ninomiya M, Sato D, Suzuki T, Hayakawa S, Kimura H.
5,7-Dihydroxyflavone Analogues May Regulate Lipopolysaccharide-Induced Inflammatory Responses by Suppressing I κ B α-Linked Akt and ERK5 Phosphorylation in RAW 264.7 Macrophages
Evid Based Complement Alternat Med
2017
7898973
PubMed ID: 28539967
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14480
Li G, Miura K, Kuno M.
Extracellular phosphates enhance activities of voltage-gated proton channels and production of reactive oxygen species in murine osteoclast-like cells
Pflugers Arch
2017
469(2):279-292
PubMed ID: 27999941
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14565
Igeta K, Kuwamura Y, Horiuchi N, Nozaki K, Shiraishi D, Aizawa M, Hashimoto K, Yamashita K, Nagai A.
Morphological and functional changes in RAW264 macrophage-like cells in response to a hydrated layer of carbonate-substituted hydroxyapatite
J Biomed Mater Res A
2017
105(4):1063-1070
PubMed ID: 28085214
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14570
Differential Regulation of IL-1β and IL-6 Release in Murine Macrophages
Differential Regulation of IL-1β and IL-6 Release in Murine Macrophages
Inflammation
2017
40(6):1933-1943
PubMed ID: 28766178
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14571
Takakuwa S, Mizuno N, Takano T, Asakawa S, Sato T, Hiratsuka M, Hirasawa N.
Down-regulation of Na +/H + exchanger 1 by Toll-like receptor stimulation in macrophages
Immunobiology
2017
222(2):176-182
PubMed ID: 27771174
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14572
Kanaoka Y, Koga M, Sugiyama K, Ohishi K, Kataoka Y, Yamauchi A.
Varenicline enhances oxidized LDL uptake by increasing expression of LOX-1 and CD36 scavenger receptors through α 7 nAChR in macrophages
Toxicology
2017
380:62-7
PubMed ID: 28202387
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14656
Tanaka KI, Sugizaki T, Kanda Y, Tamura F, Niino T, Kawahara M
Preventive Effects of Carnosine on Lipopolysaccharide-induced Lung Injury
Sci Rep
2017
7:42813
PubMed ID: 28205623
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14714
Ikeda Y, Kawai K, Ikawa A, Kawamoto K, Egami Y, Araki N.
Rac1 switching at the right time and location is essential for Fcγ receptor-mediated phagosome formation
J Cell Sci
2017
130(15):2530-2540
PubMed ID: 28600322
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14725
Minegishi S, Yumura A, Miyoshi H, Negi S, Taketani S, Motterlini R, Foresti R, Kano K, Kitagishi H.
Detection and Removal of Endogenous Carbon Monoxide by Selective and Cell-Permeable Hemoprotein Model Complexes
J Am Chem Soc
2017
139(16):5984-5991
PubMed ID: 28388069
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14773
Yokota H, Tsuzuki A, Shimada Y, Imai A, Utsumi D, Tsukahara T, Matsumoto M, Amagase K, Iwata K, Nakamura A, Yabe-Nishimura C, Kato S.
NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid-Induced Murine Colitis
J Pharmacol Exp Ther
2017
360(1):192-200
PubMed ID: 27754929
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15301
Hayashi K, Sato Y, Maruoka H, Sakamoto W, Yogo T.
Organic-Inorganic Hybrid Nanoparticles for Tracking the Same Cells Seamlessly at the Cellular, Tissue, and Whole Body Levels
ACS Biomater Sci Eng
2017
3(6):1129-1135
PubMed ID: 33429587
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7077
Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake K, Takatsu K.
Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice.
Sci Rep
2016
6:23097
PubMed ID: 26975571
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7094
Ryohei Hamaguchi, Yukihiro Kuroda
A Novel Biomarker for Cellular Toxicity and Phospholipid Accumulation by Cationic Amphiphilic Drugs.
Chromatography
2016
37:35-38
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7119
Taniguchi M, Ochiai A, Matsushima K, Tajima K, Kato T, Saitoh E, Tanaka T.
Endotoxin-neutralizing activity and mechanism of action of a cationic α-helical antimicrobial octadecapeptide derived from α-amylase of rice.
Peptides
2016
75:101-8
PubMed ID: 26643956
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7148
Ohta T, Kusano K, Ido A, Miura C, Miura T.
Silkrose: A novel acidic polysaccharide from the silkmoth that can stimulate the innate immune response.
Carbohydr Polym
2016
136:995-1001
PubMed ID: 26572439
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7157
Higuchi H, Shoji T, Murase Y, Iijima S, Nishijima K.
Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264.
Biosci. Biotechnol. Biochem.
2016
80:501-9
PubMed ID: 26540411
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7230
Takayama S, Hashimoto K, Kokubu E, Taniguchi M, Tajima K, Ochiai A, Saitoh E, Saito A, Ishihara K, Kato T.
Inhibitory effects of a novel cationic dodecapeptide [CL(14-25)] derived from cyanate lyase of rice on endotoxic activities of LPSs from Escherichia coli and periodontopathic Aggregatibacter actinomycetemcomitans.
Microb. Pathog.
2016
94:2-11
PubMed ID: 26318142
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7469
Hashimoto M, Sasaki J, Imazato S.
Investigation of the cytotoxicity of aluminum oxide nanoparticles and nanowires and their localization in L929 fibroblasts and RAW264 macrophages.
J. Biomed. Mater. Res. Part B Appl. Biomater.
2016
104:241-52
PubMed ID: 25715832
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9520
Lu Y, Cao L, Egami Y, Kawai K, Araki N.
Cofilin contributes to phagocytosis of IgG-opsonized particles but not non-opsonized particles in RAW264 macrophages.
Microscopy (Oxf)
2016
65:233-42
PubMed ID: 26754560
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9550
Takeuchi T, Nagasaka M, Shimizu M, Tamura M, Arata Y.
N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation.
Bone Rep
2016
5:15-21
PubMed ID: 28326343
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9554
Kuno M, Li G, Moriura Y, Hino Y, Kawawaki J, Sakai H.
Acid-inducible proton influx currents in the plasma membrane of murine osteoclast-like cells.
Pflugers Arch.
2016
468:837-47
PubMed ID: 26843093
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9564
Wada T, Sunaga H, Miyata K, Shirasaki H, Uchiyama Y, Shimba S.
Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression.
J. Biol. Chem.
2016
291:7004-16
PubMed ID: 26865635
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9569
Pengjam Y, Madhyastha H, Madhyastha R, Yamaguchi Y, Nakajima Y, Maruyama M.
NF-κB pathway inhibition by anthrocyclic glycoside aloin is key event in preventing osteoclastogenesis in RAW264.7 cells.
Phytomedicine
2016
23:417-28
PubMed ID: 27002412
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9573
Maeda Y, Echizen K, Oshima H, Yu L, Sakulsak N, Hirose O, Yamada Y, Taniguchi T, Jenkins BJ, Saya H, Oshima M.
Myeloid Differentiation Factor 88 Signaling in Bone Marrow-Derived Cells Promotes Gastric Tumorigenesis by Generation of Inflammatory Microenvironment.
Cancer Prev Res (Phila)
2016
9:253-63
PubMed ID: 26888865
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9607
Sugiyama K, Muroi M, Kinoshita M, Hamada O, Minai Y, Sugita-Konishi Y, Kamata Y, Tanamoto K.
NF-κB activation via MyD88-dependent Toll-like receptor signaling is inhibited by trichothecene mycotoxin deoxynivalenol.
J Toxicol Sci
2016
41:273-9
PubMed ID: 26961612
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9609
Nakabayashi H, Aoyama S, Kawahara M, Nagamune T.
Differentiation signalobody: Demonstration of antigen-dependent osteoclast differentiation from a progenitor cell line.
J. Biosci. Bioeng.
2016
122:357-63
PubMed ID: 26979343
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9612
Furuoka M, Ozaki K, Sadatomi D, Mamiya S, Yonezawa T, Tanimura S, Takeda K.
TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells.
J. Cell. Physiol.
2016
231:2761-7
PubMed ID: 26989816
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9673
Okahashi N, Nakata M, Kuwata H, Kawabata S.
Streptococcus oralis Induces Lysosomal Impairment of Macrophages via Bacterial Hydrogen Peroxide.
Infect. Immun.
2016
84:2042-2050
PubMed ID: 27113357
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9690
Elfeky M, Kaede R, Okamatsu-Ogura Y, Kimura K.
Adiponectin Inhibits LPS-Induced HMGB1 Release through an AMP Kinase and Heme Oxygenase-1-Dependent Pathway in RAW 264 Macrophage Cells.
Mediators Inflamm.
2016
2016:5701959
PubMed ID: 27313399
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9692
Kure A, Nakagawa K, Kondo M, Kato S, Kimura F, Watanabe A, Shoji N, Hatanaka S, Tsushida T, Miyazawa T.
Metabolic Fate of Luteolin in Rats: Its Relationship to Anti-inflammatory Effect.
J. Agric. Food Chem.
2016
64:4246-54
PubMed ID: 27170112
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9706
Zhang J, Hiromoto S, Yamazaki T, Niu J, Huang H, Jia G, Li H, Ding W, Yuan G.
Effect of macrophages on in vitro corrosion behavior of magnesium alloy.
J Biomed Mater Res A
2016
104:2476-87
PubMed ID: 27223576
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9740
Sunarso , Toita R, Tsuru K, Ishikawa K.
A superhydrophilic titanium implant functionalized by ozone gas modulates bone marrow cell and macrophage responses.
J Mater Sci Mater Med
2016
27:127
PubMed ID: 27344451
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9747
Arikawa M, Kakinuma Y, Noguchi T, Todaka H, Sato T.
Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation.
Eur. J. Pharmacol.
2016
789:17-26
PubMed ID: 27373848
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9818
Kanzaki H, Shinohara F, Suzuki M, Wada S, Miyamoto Y, Yamaguchi Y, Katsumata Y, Makihira S, Kawai T, Taubman MA, Nakamura Y.
A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma.
Sci Rep
2016
6:32259
PubMed ID: 27573075
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9882
Moriwaki S, Into T, Suzuki K, Miyauchi M, Takata T, Shibayama K, Niida S.
γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.
Sci Rep
2016
6:35930
PubMed ID: 27775020
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9922
Yamawaki T, Ito E, Mukai A, Ueno M, Yamada J, Sotozono C, Kinoshita S, Hamuro J.
The Ingenious Interactions Between Macrophages and Functionally Plastic Retinal Pigment Epithelium Cells.
Invest. Ophthalmol. Vis. Sci.
2016
57:5945-5953
PubMed ID: 27820950
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9969
Domon H, Oda M, Maekawa T, Nagai K, Takeda W, Terao Y.
Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis.
Sci Rep
2016
6:38013
PubMed ID: 27892542
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10852
Kejuan Li, Xi Yang, Xuansheng Hu, Chao Han, Zhongfang Lei, Zhenya Zhang
In vitro antioxidant, immunomodulatory and anticancer activities of two fractions of aqueous extract from Helicteres angustifolia L. root
Journal of the Taiwan Institute of Chemical Engineers
2016
61:75-82
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10857
Clinical Evaluation of Novel Natural Polysaccharides Sacran as a Skincare Material for Atopic Dermatitis Patients
Journal of Cosmetics, Dermatological Sciences and Applications
2016
6, 9-18
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10869
Isolation and Biochemical Characterization of Mucus Proteins in Japanese Bunching Onion (Allium fistulosum) Green Leaves
Food Science and Technology Research
2016
22
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9409
Nobutaka Sato 1, Jiro Ichikawa 1, Masanori Wako, Tetsuro Ohba, Masanori Saito, Hironao Sato, Kensuke Koyama, Tetsuo Hagino, Jonathan G Schoenecker, Takashi Ando, Hirotaka Haro
Thrombin Induced by the Extrinsic Pathway and PAR-1 Regulated Inflammation at the Site of Fracture Repair
Bone
2016
83:23-34
PubMed ID: 26475502
|
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10109
Yusuke Kono, Ayu Iwasaki, Kenta Matsuoka, Takuya Fujita
Effect of Mechanical Agitation on Cationic Liposome Transport Across an Unstirred Water Layer in Caco-2 Cells
Biol Pharm Bull
2016
39(8):1293-9
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12622
Goto T, Naknukool S, Yoshitake R, Hanafusa Y, Tokiwa S, Li Y, Sakamoto T, Nitta T, Kim M, Takahashi N, Yu R, Daiyasu H, Seno S, Matsuda H, Kawada T.
Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes
Cytokinec
2016
77:107-14
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Hashimoto M, Kawai K, Kawakami H, Imazato S.
Matrix metalloproteases inhibition and biocompatibility of gold and platinum nanoparticles
J Biomed Mater Res A
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Ichikawa N, Yamashita K, Funakoshi T, Ichihara S, Fukai M, Ogura M, Kobayashi N, Zaitsu M, Yoshida T, Shibasaki S, Koshizuka Y, Tsunetoshi Y, Sato M, Einama T, Ozaki M, Umezawa K, Suzuki T, Todo S.
Novel anti-inflammatory agent 3-[(dodecylthiocarbonyl)-methyl]-glutarimide ameliorates murine models of inflammatory bowel disease
Inflamm Res
2016
65(3):245-60
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12936
Hayashida Y, Ikeda Y, Sawada K, Kawai K, Kato T, Kakehi Y, Araki N.
Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor
Int J Cancer
2016
139(3):700-11
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Nagahara H, Yamamoto A, Seno T, Obayashi H, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y.
Allograft inflammatory factor-1 in the pathogenesis of bleomycin-induced acute lung injury
Biosci Trends
2016
10(1):47-53.
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13985
Nakayama M, Nakamura A, Hondou T, Miyata H.
Evaluation of cell viability, DNA single-strand breaks, and nitric oxide production in LPS-stimulated macrophage RAW264 exposed to a 50-Hz magnetic field
Int J Radiat Biol
2016
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Yamamoto S, Ohta N, Matsumoto A, Horiguchi Y, Koide M, Fujino Y.
Haloperidol Suppresses NF-kappaB to Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Response in RAW 264 Cells
Med Sci Monit
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22:367-72
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14110
Taki M, Tagami T, Fukushige K, Ozeki T.
Fabrication of nanocomposite particles using a two-solution mixing-type spray nozzle for use in an inhaled curcumin formulation
Int J Pharm
2016
511(1):104-110
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14164
Yiting Li, Shili Meng, Min Shi, Xuansheng Hu, Yingnan Yang, Zhenya Zhang
Bioactivity Evaluation of Crude Polysaccharide from Rice Bran Fermented by Preussia Aemulans and the Changes in its Nutritional Contents
Journal of Food Biochemistry
2016
40:664-672
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Ito S, Tanaka Y, Oshino R, Okado S, Hori M, Isobe KI.
GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation
Cell Death Dis
2016
7(5):e2219
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15302
Yuichi Masuda, Chitose Maruyama, Kyuichi Kawabata, Yoshimitsu Hamano, Takayuki Doi
Synthesis of (2S,3R,4R)-3,4-dihydroxyarginine and its inhibitory activity against nitric oxide synthase
Tetrahedron
2016
72:5602-5611
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7085
Hosokawa T, Tsuchiya Y, Okubo N, Kunimoto T, Minami Y, Fujiwara H, Umemura Y, Koike N, Kubo T, Yagita K.
Robust Circadian Rhythm and Parathyroid Hormone-Induced Resetting during Hypertrophic Differentiation in ATDC5 Chondroprogenitor Cells.
Acta Histochem Cytochem
2015
48:165-71
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Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa TO, Kataoka Y, Yamamura K.
Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo.
Sci Rep
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5:17205
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Washio K, Kobayashi M, Saito N, Amagasa M, Kitamura H.
Propolis Ethanol Extract Stimulates Cytokine and Chemokine Production through NF-κB Activation in C2C12 Myoblasts.
Evid Based Complement Alternat Med
2015
2015:349751
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7221
Sawada Y, Sakamoto Y, Toh M, Ohara N, Hatanaka Y, Naka A, Kishimoto Y, Kondo K, Iida K.
Milk-derived peptide Val-Pro-Pro (VPP) inhibits obesity-induced adipose inflammation via an angiotensin-converting enzyme (ACE) dependent cascade.
Mol Nutr Food Res
2015
59:2502-10
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7229
Inoue K, Imai Y.
Fatostatin, an SREBP inhibitor, prevented RANKL-induced bone loss by suppression of osteoclast differentiation.
Biochim. Biophys. Acta
2015
1852:2432-41
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Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.
IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.
J. Clin. Invest.
2015
125:3269-79
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Tang L, Okamoto S, Shiuchi T, Toda C, Takagi K, Sato T, Saito K, Yokota S, Minokoshi Y.
Sympathetic Nerve Activity Maintains an Anti-Inflammatory State in Adipose Tissue in Male Mice by Inhibiting TNF-α Gene Expression in Macrophages.
Endocrinology
2015
156:3680-94
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Hashimoto M, Sasaki JI, Yamaguchi S, Kawai K, Kawakami H, Iwasaki Y, Imazato S.
Gold Nanoparticles Inhibit Matrix Metalloproteases without Cytotoxicity.
J. Dent. Res.
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94:1085-91
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Suzuki N, Takimoto K, Kawashima N.
Cathepsin K Inhibitor Regulates Inflammation and Bone Destruction in Experimentally Induced Rat Periapical Lesions.
J Endod
2015
41:1474-9
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7420
Miyazaki T, Miyauchi S, Anada T, Tawada A, Suzuki O.
Chondroitin Sulfate-E Binds to Both Osteoactivin and Integrin αVβ3 and Inhibits Osteoclast Differentiation.
J. Cell. Biochem.
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116:2247-57
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Takeuchi T, Shimakawa G, Tamura M, Yokosawa H, Arata Y.
ISG15 regulates RANKL-induced osteoclastogenic differentiation of RAW264 cells.
Biol. Pharm. Bull.
2015
38:482-6
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Hashimoto M, Imazato S.
Cytotoxic and genotoxic characterization of aluminum and silicon oxide nanoparticles in macrophages.
Dent Mater
2015
31:556-64
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7467
Kawabata K, Kato Y, Sakano T, Baba N, Hagiwara K, Tamura A, Baba S, Natsume M, Ohigashi H.
Effects of phytochemicals on in vitro anti-inflammatory activity of Bifidobacterium adolescentis.
Biosci. Biotechnol. Biochem.
2015
79:799-807
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Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M.
Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury.
Am. J. Physiol. Renal Physiol.
2015
308:F878-87
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7501
Lai YT, Sato M, Ohta S, Akamatsu K, Nakao S, Sakai Y, Ito T.
Preparation of uniform-sized hemoglobin-albumin microspheres as oxygen carriers by Shirasu porous glass membrane emulsification technique.
Colloids Surf B Biointerfaces
2015
127:1-7
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7505
Kim YI, Mohri S, Hirai S, Lin S, Goto T, Ohyane C, Sakamoto T, Takahashi H, Shibata D, Takahashi N, Kawada T.
Tomato extract suppresses the production of proinflammatory mediators induced by interaction between adipocytes and macrophages.
Biosci. Biotechnol. Biochem.
2015
79:82-7
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7517
Taniguchi M, Ochiai A, Takahashi K, Nakamichi S, Nomoto T, Saitoh E, Kato T, Tanaka T.
Antimicrobial activity and mechanism of action of a novel cationic α-helical octadecapeptide derived from α-amylase of rice.
Biopolymers
2015
104:73-83
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7526
F Shima, T Akagi, M Shudo, E Mochizuki, T Tsuda, S Kuwabata M Akashi
Interaction between living cells and polymeric particles: potential application of ionic liquid for evaluating the cellular uptake of biodegradable polymeric particles composed of poly(amino acid).
Polymer Journal
2015
47:631-638
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Uto T, Tung NH, Taniyama R, Miyanowaki T, Morinaga O, Shoyama Y.
Anti-inflammatory Activity of Constituents Isolated from Aerial Part of Angelica acutiloba Kitagawa.
Phytother Res
2015
29(12):1956-63
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6621
Koyama T, Kamemura K.
Global increase in O-linked N-acetylglucosamine modification promotes osteoblast differentiation.
Exp Cell Res
2015
338(2):194-202
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9365
Akio Watanabe, Momochika Kumagai, Takashi Mishima, Junya Ito, Yurika Otoki, Teppei Harada, Tsuyoshi Kato, Mikihiko Yoshida, Misora Suzuki, Izumi Yoshida, Kazuhiro Fujita, Masatoshi Watai, Kiyotaka Nakagawa, Teruo Miyazawa
Toddaculin, Isolated From of Toddalia Asiatica (L.) Lam., Inhibited Osteoclastogenesis in RAW 264 Cells and Enhanced Osteoblastogenesis in MC3T3-E1 Cells
PLoS One
2015
10(5):e0127158
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9378
R Toita, Sunarso, A N Rashid, K Tsuru, K Ishikawa
Modulation of the Osteoconductive Property and Immune Response of Poly(ether Ether Ketone) by Modification With Calcium Ions
J Mater Chem B
2015
3(44):8738-8746
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10173
Yao-Tong Lai, Seiichi Ohta, Kazuki Akamatsu, Shin-Ichi Nakao, Yasuyuki Sakai, Taichi Ito
Size-dependent Interaction of Cells and Hemoglobin-Albumin Based Oxygen Carriers Prepared Using the SPG Membrane Emulsification Technique
Biotechnol Prog .
2015
31(6):1676-84
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10195
Akihiko Nagao, Takashi Maoka, Hiroshi Ono, Eiichi Kotake-Nara, Miyuki Kobayashi, Mie Tomita
A 3-hydroxy β-End Group in Xanthophylls Is Preferentially Oxidized to a 3-oxo ε-End Group in Mammals
J Lipid Res
2015
56(2):449-62
PubMed ID: 25502844
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12234
Masayori Hagimori, Naoko Mizuyama, Yoshinori Tominaga, Takahiro Mukai,Hideo Saji
A low-molecular-weight fluorescent sensor with Zn2+ dependent bathochromic shift of emission wavelength and its imaging in living cells
Dyes and Pigments
2015
113:205-209
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12237
Shiro Kato, Yuki Masuda, Morichika Konishi, Tadao Oikawa
Enantioselective analysis of D- and L-amino acids from mouse macrophages using high performance liquid chromatography
J Pharm Biomed Anal
2015
116:101-4
PubMed ID: 25982753
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12245
Takashi Ando, Takayuki Komatsu, Yoshikazu Naiki, Takashi Yokochi, Daisuke Watanabe, Naoki Koide
Pretreatment of LPS inhibits IFN-β-induced STAT1 phosphorylation through SOCS3 induced by LPS
Biomed Pharmacother
2015
76:1-5
PubMed ID: 26653542
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12252
Yoshiro Kato, Hideki Kamiya, Naoki Koide, Erdenezaya Odkhuu, Takayuki Komatsu, Atsuko Watarai, Masaki Kondo, Koichi Kato, Jiro Nakamura, Takashi Yokochi
Irbesartan attenuates production of high-mobility group box 1 in response to lipopolysaccharide via downregulation of interferon-β production
Int Immunopharmacol
2015
26(1):97-102
PubMed ID: 25817178
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12259
Shusong Wu, Xi He, Xiaosong Wu, Si Qin, Jianhua He, Shirui Zhang, De-Xing Hou
Inhibitory effects of blue honeysuckle (Lonicera caerulea L) on adjuvant-induced arthritis in rats: Crosstalk of anti-inflammatory and antioxidant effects
J Functional Foods
2015
17:514-515
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13961
Fujioka K, Kishida T, Ejima A, Yamamoto K, Fujii W, Murakami K, Seno T, Yamamoto A, Kohno M, Oda R, Yamamoto T, Fujiwara H, Kawahito Y, Mazda O.
Inhibition of osteoclastogenesis by osteoblast-like cells genetically engineered to produce interleukin-10
Biochem Biophys Res Commun
2015
456(3):785-91
PubMed ID: 25514036
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14465
Okinaga T, Ariyoshi W, Nishihara T.
Aggregatibacter actinomycetemcomitans Invasion Induces Interleukin-1β Production Through Reactive Oxygen Species and Cathepsin B
J Interferon Cytokine Res
2015
35(6):431-40
PubMed ID: 25789553
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14969
Kiyomiya H, Ariyoshi W, Okinaga T, Kaneuji T, Mitsugi S, Sakurai T, Habu M, Yoshioka I, Tominaga K, Nishihara T.
IL-33 inhibits RANKL-induced osteoclast formation through the regulation of Blimp-1 and IRF-8 expression
Biochem Biophys Res Commun
2015
460(2):320-6
PubMed ID: 25795135
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14983
He YM, Zhu S, Ge YW, Kazuma K, Zou K, Cai SQ, Komatsu K.
The anti-inflammatory secoiridoid glycosides from gentianae scabrae radix: the root and rhizome of Gentiana scabra
J Nat Med
2015
69(3):303-12
PubMed ID: 25750086
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14991
Komiya M, Fujii G, Miyamoto S, Takahashi M, Ishigamori R, Onuma W, Ishino K, Totsuka Y, Fujimoto K, Mutoh M.
Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK-A(y) and Apc mutant Min mice
Cancer Sci
2015
106(11):1499-505
PubMed ID: 26310859
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15020
Mori K, Ouchi K, Hirasawa N.
The Anti-Inflammatory Effects of Lion's Mane Culinary-Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) in a Coculture System of 3T3-L1 Adipocytes and RAW264 Macrophages
Int J Med Mushrooms
2015
17(7):609-18
PubMed ID: 26559695
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15021
Tan H, Ashour A, Katakura Y, Shimizu K.
A structure-activity relationship study on antiosteoclastogenesis effect of triterpenoids from the leaves of loquat (Eriobotrya japonica)
Phytomedicine
2015
22(4):498-503
PubMed ID: 25925972
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15028
Inaba H, Yoshigai E, Okuyama T, Murakoshi M, Sugiyama K, Nishino H, Nishizawa M.
Antipyretic analgesic drugs have different mechanisms for regulation of the expression of inducible nitric oxide synthase in hepatocytes and macrophages
Nitric Oxide
2015
44:61-70
PubMed ID: 25499030
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15148
Kojima C, Kameyama R, Yamada M, Ichikawa M, Waku T, Handa A, Tanaka N.
Ovalbumin Delivery by Guanidine-Terminated Dendrimers Bearing an Amyloid-Promoting Peptide via Nanoparticle Formulation
Bioconjug Chem
2015
26(8):1804-10
PubMed ID: 26186179
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13891
Nakamura R, Kayamori K, Oue E, Sakamoto K, Harada K, Yamaguchi A.
Transforming growth factor-β synthesized by stromal cells and cancer cells participates in bone resorption induced by oral squamous cell carcinoma
Biochem Biophys Res Commun
2015
458(4):777-82
PubMed ID: 25681764
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15208
Wang Q, Yokoo H, Takashina M, Sakata K, Ohashi W, Abedelzaher LA, Imaizumi T, Sakamoto T, Hattori K, Matsuda N, Hattori Y.
Anti-Inflammatory Profile of Levosimendan in Cecal Ligation-Induced Septic Mice and in Lipopolysaccharide-Stimulated Macrophages
Crit Care Med
2015
43(11):e508-20
PubMed ID: 26468714
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15255
Asakawa S, Kishimoto Y, Takano T, Okita K, Takakuwa S, Sato T, Hiratsuka M, Takeuchi O, Hirasawa N.
Nickel ions selectively inhibit lipopolysaccharide-induced interleukin-6 production by decreasing its mRNA stability
PLoS One
2015
10(3):e0119428
PubMed ID: 25742007
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15444
Oka H, Kitagawa M, Takata T.
F-spondin inhibits differentiation of clastic precursors via lipoprotein receptor-related protein 8 (LRP8)
J Periodontol
2015
86(3):465-72
PubMed ID: 25299387
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15446
Nomura H, Takanashi S, Tanaka M, Haniu H, Aoki K, Okamoto M, Kobayashi S, Takizawa T, Usui Y, Oishi A, Kato H, Saito N.
Specific biological responses of the synovial membrane to carbon nanotubes
Sci Rep
2015
5:14314
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15305
Oh-Hashi K, Sone A, Hikiji T, Hirata Y, Vitiello M, Fedele M, Ishigaki S, Sobue G, Kiuchi K.
Transcriptional and post-transcriptional regulation of transmembrane protein 132A
Mol Cell Biochem
2015
405(1-2):291-9
PubMed ID: 25926156
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15479
Ito S, Tanaka Y, Oshino R, Aiba K, Thanasegaran S, Nishio N, Isobe K.
GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy
Sci Rep
2015
5:8327
PubMed ID: 25659802
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15103
Cuilian Tao, Yufang Zhu, Xianglan Li, Nobutaka Hanagata
Binding of CpG oligodeoxynucleotides to mesoporous silica nanoparticles for enhancing delivery efficiency
Microporous and Mesoporous Materials
2015
204:91-98
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15313
Seiji GODA, Hiroshi HAYASHI, Yosuke UJII, Osamu TAKEUCHI, Reiko KOMASA, Eisuke DOMAE, Kazuyo YAMAMOTO, Naoyuki MATSUMOTO, Takashi IKEO
Fibronectin inhibited RANKL-induced differentiation into osteoclast
Journal of Oral Tissue Engineering
2014:227-233
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6334
Itoh T, Tsuchida A, Muramatsu Y, Ninomiya M, Ando M, Tsukamasa Y, Koketsu M.
Antimicrobial and anti-inflammatory properties of nostocionone isolated from Nostoc commune Vauch and its derivatives against Propionibacterium acnes.
Anaerobe
2014
27:56-63
PubMed ID: 24699048
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2777
Yamasaki T, Ariyoshi W, Okinaga T, Adachi Y, Hosokawa R, Mochizuki S, Sakurai K, Nishihara T.
The dectin 1 agonist curdlan regulates osteoclastogenesis by inhibiting nuclear factor of activated T cells cytoplasmic 1 (NFATc1) through Syk kinase.
J Biol Chem
2014
289(27):19191-203
PubMed ID: 24821724
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6607
Nakazato R, Takarada T, Watanabe T, Nguyen BT, Ikeno S, Hinoi E, Yoneda Y.
Constitutive and functional expression of runt-related transcription factor-2 by microglial cells.
Neurochem Int
2014
74:24-35
PubMed ID: 24768841
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9114
Erdenezaya Odkhuu, Takayuki Komatsu, Yoshikazu Naiki, Naoki Koide, Takashi Yokochi
Sendai Virus C Protein Inhibits Lipopolysaccharide-Induced Nitric Oxide Production Through Impairing Interferon-β Signaling
Int Immunopharmacol
2014
23 (1), 267-72
PubMed ID: 25242386
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9323
Ran Zhao, Masayoshi Kamon, Kazuichi Sakamoto
(–)-Epigallocatechingallate Interferes RANKL/RANK Signal Pathway and Induces Apoptosis during Osteoclastogenesis in RAW264 Cell
Food and Nutrition Sciences
2014
5:107-116
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9348
W Ariyoshi, T Okinaga, C B Knudson, W Knudson, T Nishihara
High Molecular Weight Hyaluronic Acid Regulates Osteoclast Formation by Inhibiting Receptor Activator of NF-κB Ligand Through Rho Kinase
Osteoarthritis Cartilage
2014
22(1):111-20
PubMed ID: 24185105
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9349
Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo
Responses of RAW264.7 Macrophages to Water-Dispersible Gold and Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds
J Biomed Mater Res A
2014
102(6):1838-49
PubMed ID: 23784947
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9351
Miki Tadaishi, Yoriko Nishide, Yuko Tousen, Marlena C Kruger, Yoshiko Ishimi
Cooperative Effects of Soy Isoflavones and Carotenoids on Osteoclast Formation
J Clin Biochem Nutr
2014
54(2):109-15
PubMed ID: 24688220
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12850
Tada R, Koide Y, Yamamuro M, Tanaka R, Hidaka A, Nagao K, Aramaki Y.
Maleylated-BSA suppresses lipopolysaccharide-induced IL-6 production by activating the ERK-signaling pathway in murine RAW264.7 cells
Int Immunopharmacol
2014
19(1):5-9
PubMed ID: 24406428
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15027
Dan Zhu, Hongyi Sun, Shuhong Li, Xuansheng Hu, Xi Yuan, Chao Han, Zhenya Zhang
Influence of Drying Methods on Antioxidant Activities and Immunomodulatory of Aqueous Extract From Soybean Curd Residue Fermentated by Grifola frondosa
International Journal of Biology
2014
7:82-92
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15306
Itoh T, Koketsu M, Yokota N, Touho S, Ando M, Tsukamasa Y.
Reduced scytonemin isolated from Nostoc commune suppresses LPS/IFNγ-induced NO production in murine macrophage RAW264 cells by inducing hemeoxygenase-1 expression via the Nrf2/ARE pathway
Food Chem Toxicol
2014
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PubMed ID: 24795232
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15307
Daisuke Yamanaka, Katsuya Tajima, Yoshiyuki Adachi, Ken-ichi Ishibashi, Noriko N. Miura, Masuro Motoi, Naohito Ohno
Effect of polymeric caffeic acid on antitumour activity and natural killer cell activity in mice
Journal of Functional Foods
2014
6:513-522
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15309
Kusunoki H, Taniyama Y, Otsu R, Rakugi H, Morishita R.
Anti-inflammatory effects of hepatocyte growth factor on the vicious cycle of macrophages and adipocytes
Hypertens Res
2014
37(6):500-6
PubMed ID: 24621470
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15310
Sato S, Sakurai T, Ogasawara J, Shirato K, Ishibashi Y, Oh-ishi S, Imaizumi K, Haga S, Hitomi Y, Izawa T, Ohira Y, Ohno H, Kizaki T.
Direct and indirect suppression of interleukin-6 gene expression in murine macrophages by nuclear orphan receptor REV-ERBα
ScientificWorldJournal
2014
2014:685854
PubMed ID: 25401152
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15311
Araki N, Ikeda Y, Kato T, Kawai K, Egami Y, Miyake K, Tsurumaki N, Yamaguchi M.
Development of an automated fluorescence microscopy system for photomanipulation of genetically encoded photoactivatable proteins (optogenetics) in live cells
Microscopy (Oxf)
2014
63(3):255-60
PubMed ID: 24523516
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15312
Sato Y, Hara H, Okuno T, Ozaki N, Suzuki S, Yokomizo T, Kaisho T, Yoshida H.
IL-27 affects helper T cell responses via regulation of PGE2 production by macrophages
Biochem Biophys Res Commun
2014
451(2):215-21
PubMed ID: 25088998
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15314
Sarntivijai S, Lin Y, Xiang Z, Meehan TF, Diehl AD, Vempati UD, Schürer SC, Pang C, Malone J, Parkinson H, Liu Y, Takatsuki T, Saijo K, Masuya H, Nakamura Y, Brush MH, Haendel MA, Zheng J, Stoeckert CJ, Peters B, Mungall CJ, Carey TE, States DJ, Athey BD, He Y.
CLO: The cell line ontology
J Biomed Semantics
2014
5:37
PubMed ID: 25852852
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15315
Suk Hyun Choi, Dong-Seok Kim, Nobuyuki Kozukue, Hyun-Jeong Kim, Yosuke Nishitani, Masashi Mizuno, Carol E. Levin, Mendel Friedman
Protein, free amino acid, phenolic, β-carotene, and lycopene content, and antioxidative and cancer cell inhibitory effects of 12 greenhouse-grown commercial cherry tomato varieties
Journal of Food Composition and Analysis
2014
34:115-127
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15316
Xu Y, Ito T, Fushimi S, Takahashi S, Itakura J, Kimura R, Sato M, Mino M, Yoshimura A, Matsukawa A.
Spred-2 deficiency exacerbates lipopolysaccharide-induced acute lung inflammation in mice
PLoS One
2014
9(9):e108914
PubMed ID: 25275324
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15317
Uehara K, Takahashi A, Watanabe M, Nomura Y.
Shark protein improves bone mineral density in ovariectomized rats and inhibits osteoclast differentiation
Nutrition
2014
30(6):719-25
PubMed ID: 24800672
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15319
Ueno-Shuto K, Kato K, Tasaki Y, Sato M, Sato K, Uchida Y, Sakai H, Ono T, Suico MA, Mitsutake K, Tokutomi N, Kai H, Shuto T.
Lipopolysaccharide decreases single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR) expression by suppressing specificity protein 1 (Sp1) via the Toll-like receptor 4 (TLR4)-p38 pathway in monocytes and neutrophils
J Biol Chem
2014
289(26):18097-109
PubMed ID: 24821721
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15320
Phyu Phyu Khine Zar, Akiko Morishita, Fumio Hashimoto, Kozue Sakao, Makoto Fujii, Koji Wada, De-Xing Hou
Anti-inflammatory effects and molecular mechanisms of loquat (Eriobotrya japonica) tea
Journal of Functional Foods
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6:523-533
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Inoue M, Tanabe H, Nakashima K, Ishida Y, Kotani H.
Rexinoids isolated from Sophora tonkinensis with a gene expression profile distinct from the synthetic rexinoid bexarotene
J Nat Prod
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Kato Y, Kamiya H, Koide N, Odkhuu E, Komatsu T, Dagvadorj J, Watarai A, Kondo M, Kato K, Nakamura J, Yokochi T.
Spironolactone inhibits production of proinflammatory mediators in response to lipopolysaccharide via inactivation of nuclear factor-κB
Immunopharmacol Immunotoxicol
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36(3):237-41
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T. Atsumi, A. Iwashita, I. Ohtsuka, N. Kakiuchi, Y. Sasaki, M. Mikage, K. Toriizuka
Effects of Atractylodis Lanceae Rhizoma on inflammatory mediator production from the RAW264 macrophage cell line
J Traditional Medicines
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30:124-131
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Takeshi KAWAHARA, Daichi NAKAYAMA, Keisuke TODA, Shyuichiro INAGAKI, Katsumi TANAKA, Hisako YASUI
Suppressive Effect of Wild Saccharomyces cerevisiae and Saccharomyces paradoxus Strains on Ige Production by Mouse Spleen Cells
Food Sci. Technol. Res
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19 (6), 1019 – 1027
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Ito S, Tanaka Y, Nishio N, Thanasegaran S, Isobe K.
Establishment of self-renewable GM-CSF-dependent immature macrophages in vitro from murine bone marrow.
PLoS One
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Horibe K, Nakamichi Y, Uehara S, Nakamura M, Koide M, Kobayashi Y, Takahashi N, Udagawa N.
Roles of cathelicidin-related antimicrobial peptide in murine osteoclastogenesis.
Immunology
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140(3):344-51
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Etoh T, Kim YP, Ohsaki A, Komiyama K, Hayashi M.
Inhibitory effect of erythraline on Toll-like receptor signaling pathway in RAW264.7 cells.
Biol Pharm Bull
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Etoh T, Kim YP, Tanaka H, Hayashi M.
Anti-inflammatory effect of berkeleyacetal C through the inhibition of interleukin-1 receptor-associated kinase-4 activity.
Eur J Pharmacol
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698(1-3):435-43
PubMed ID: 23127497
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Kyoko Ueda, Ryoko Kawabata, Takashi Irie, Yoshiaki Nakai, Yukinobu Tohya, Takemasa Sakaguchi
Inactivation of Pathogenic Viruses by Plant-Derived Tannins: Strong Effects of Extracts From Persimmon (Diospyros Kaki) on a Broad Range of Viruses
PLoS One
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8 (1), e55343
PubMed ID: 23372851
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Hiroki Ishikawa, Naoki Awano, Toshie Fukui, Hiraku Sasaki, Shigeru Kyuwa
The Protective Effects of Lactoferrin Against Murine Norovirus Infection Through Inhibition of Both Viral Attachment and Replication
Biochem Biophys Res Commun
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434 (4), 791-6
PubMed ID: 23603257
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Akari Ishisaka, Kyuichi Kawabata, Satomi Miki, Yuko Shiba, Shoko Minekawa, Tomomi Nishikawa, Rie Mukai, Junji Terao, Yoshichika Kawai
Mitochondrial Dysfunction Leads to Deconjugation of Quercetin Glucuronides in Inflammatory Macrophages
PLoS One
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8 (11), e80843
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Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo
Micromorphological Cellular Responses of MC3T3-E1 and RAW264.7 After Exposure to Water-Dispersible Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds
Dent Mater J
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32(5):725-33
PubMed ID: 24088827
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Yuriko Furuya, Atsushi Inagaki, Masud Khan, Kaoru Mori, Josef M Penninger, Midori Nakamura, Nobuyuki Udagawa, Kazuhiro Aoki, Keiichi Ohya, Kohji Uchida, Hisataka Yasuda
Stimulation of Bone Formation in Cortical Bone of Mice Treated With a Receptor Activator of Nuclear factor-κB Ligand (RANKL)-binding Peptide That Possesses Osteoclastogenesis Inhibitory Activity
J Biol Chem
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288(8):5562-71
PubMed ID: 23319583
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Hirohiko Okamura, Di Yang, Kaya Yoshida, Tatsuji Haneji
Protein Phosphatase 2A Cα Is Involved in Osteoclastogenesis by Regulating RANKL and OPG Expression in Osteoblasts
FEBS Lett
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587(1):48-53
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Kazuhiro Nakaya, Makoto Ayaori, Harumi Uto-Kondo, Grace Megumi Sotherden, Takafumi Nishida, Haruka Katamoto, Yuko Miura, Shunichi Takiguchi, Emi Yakushiji, Maki Iizuka, Masatsune Ogura, Makoto Sasaki, Makiko Yogo, Tomohiro Komatsu, Takeshi Adachi, Chizuko Maruyama, Katsunori Ikewaki
Overexpression of stearoyl-coenzyme A desaturase 1 in macrophages promotes reverse cholesterol transport
Biochim Biophys Acta
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1831(8):1402-11
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Suzuki S, Nishio SI, Ishii H, Sekido T, Takeshige K, Ohkubo Y, Hiwatashi D, Takeda T, Komatsu M.
Possible roles of the AP-1 site in the cytosolic T3 binding protein promoter and insights into its physiological significance.
Horm Metab Res
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45(7):501-6
PubMed ID: 23508717
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13737
Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Masahiro Iijima, Kazuhiko Endo
Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Masahiro Iijima, Kazuhiko Endo
Journal of Biomaterials and Tissue Engineering
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Tsolmongyn B, Koide N, Odkhuu E, Haque A, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Lipopolysaccharide prevents valproic acid-induced apoptosis via activation of nuclear factor-κB and inhibition of p53 activation
Cell Immunol
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282(2):100-5
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15324
Rui Tada, Yusuke Koide, Mitsuaki Yamamuro, Akira Hidaka, Koichiro Nagao, Yoichi Negishi, Yukihiko Aramaki
Maleylated-BSA induces TNF-α production through the ERK and NF-κB signaling pathways in murine RAW264.7 macrophages
Open Journal of Immunology
2013
3:184-189
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15325
Yuka Takasugi, Futoshi Kurai, Issei Kazume, Masaki Otsuka, Yoichi Negishi, Rui Tada, Yukihiko Aramaki
Down Regulation of MyD88 in Macrophages Treated with Liposomes Composed of Phosphatidylserine
Pharmacology & Pharmacy
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4:248-254
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15326
Yuko Katao, Hirofumi Sawai, Mika Shishido, Aki Omae, Wen Liao, Kaoru Inami, Naoyuki Matsumoto
Augmentation of RANKL-induced osteoclast differentiation by Z-VAD-fmk, a pan-caspase inhibitor
Journal of Osaka Dental University
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47:41-46
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Fumiaki Shima, Koshi Kawakami, Takami Akagi, Eiko Mochizuki, Tetsuya Tsuda, Susumu Kuwabata, Mitsuru Akashi
Simple Observation of the Interaction between Nanoparticles and Cells by Scanning Electron Microscopy Employing Ionic Liquid
Bulletin of the Chemical Society of Japan
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86:153-158
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Fujii M, Kawai K, Egami Y, Araki N.
Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation
Sci Rep
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Muramatsu S, Tanaka S, Mogushi K, Adikrisna R, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Nakayama K, Tanaka H, Yamaoka S, Arii S.
Visualization of stem cell features in human hepatocellular carcinoma reveals in vivo significance of tumor-host interaction and clinical course
Hepatology
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58(1):218-28
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Nishimura M, Nii T, Trimova G, Miura S, Umezawa K, Ushiyama A, Kubota T.
The NF-κB specific inhibitor DHMEQ prevents thrombus formation in a mouse model of antiphospholipid syndrome
J Nephropathol
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2(2):114-21
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Hiroshi HAYASHI, Yosuke UJII, Seiji GODA, Naoyuki MATSUMOTO
Effect of VCAM-1 on the Differentiation into Osteoclast
Journal of Oral Tissue Engineering
2013
11:154-162
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Higashimura Y, Naito Y, Takagi T, Mizushima K, Hirai Y, Harusato A, Ohnogi H, Yamaji R, Inui H, Nakano Y, Yoshikawa T.
Oligosaccharides from agar inhibit murine intestinal inflammation through the induction of heme oxygenase-1 expression
J Gastroenterol
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48(8):897-909
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Tanaka K, Ishihara T, Sugizaki T, Kobayashi D, Yamashita Y, Tahara K, Yamakawa N, Iijima K, Mogushi K, Tanaka H, Sato K, Suzuki H, Mizushima T.
Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease
Nat Commun
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Seikou Kim, Kouichi Yamamoto, Yusuke Nakamura, Yuichi Otoyo, Atsushi Yamatodani
A Possible Mechanism of Cisplatin-Induced Tumor Necrosis Factor (TNF)-α Production in Murine Macrophages
Pharmacology & Pharmacy
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4:146-151
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15336
Tadahiro Etoh, Yong P. Kim, Masahiko Hayashi, Michiko Suzawa, Shiming Li, Chi-Tang Ho, Kanki Komiyama
Inhibitory effect of a formulated extract from multiple citrus peels on LPS-induced inflammation in RAW 246.7 macrophages
Functional Foods in Health and Disease
2013
3:242
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Phyu Phyu Khine Zar, Kozue Sakao, Fumio Hashimoto, Akiko Morishita, Makoto Fujii, Koji Wada, De-Xing Hou
Antioxidant and anti-inflammatory activities of loquat (Eriobotrya japonica) tea
Functional Foods in Health and Disease
2013
3:447
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Xi Yang, Yingnan Yang, Min Shi, Yuepeng Wang, Zhenya Zhang, Yifeng Lu
Optimisation of Anthocyanin Extraction from Purple Pitaya and Verification of Antioxidant Properties, Antiproliferative Activity and Macrophage Proliferation Activity
International Journal of Biology
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Funakoshi T, Yamashita K, Ichikawa N, Fukai M, Suzuki T, Goto R, Oura T, Kobayashi N, Katsurada T, Ichihara S, Ozaki M, Umezawa K, Todo S.
A novel NF-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice.
J Crohns Colitis
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Takano K, Sato K, Negishi Y, Aramaki Y.
Involvement of actin cytoskeleton in macrophage apoptosis induced by cationic liposomes.
Arch. Biochem. Biophys.
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518:89-94
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Takahashi K, Sugiyama T, Tokoro S, Neri P, Mori H.
Inhibition of interferon-γ-induced nitric oxide production by 10-hydroxy-trans-2-decenoic acid through inhibition of interferon regulatory factor-8 induction.
Cell. Immunol.
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Uto T, Morinaga O, Tanaka H, Shoyama Y.
Analysis of the synergistic effect of glycyrrhizin and other constituents in licorice extract on lipopolysaccharide-induced nitric oxide production using knock-out extract.
Biochem. Biophys. Res. Commun.
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417:473-8
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Nakagawa S, Arai Y, Kishida T, Hiraoka N, Tsuchida S, Inoue H, Sakai R, Mazda O, Kubo T.
Lansoprazole inhibits nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells.
Inflammation
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35:1062-8
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Uto T, Qin GW, Morinaga O, Shoyama Y.
17-Hydroxy-jolkinolide B, a diterpenoid from Euphorbia fischeriana, inhibits inflammatory mediators but activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine macrophages.
Int. Immunopharmacol.
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Uchida M, Oyanagi E, Kremenik MJ, Sasaki J, Yano H.
Interferon-beta, but not tumor necrosis factor-alpha, production in response to poly I:C is maintained despite exhaustive exercise in mice.
J Physiol Sci
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Sugiyama T, Takahashi K, Tokoro S, Gotou T, Neri P, Mori H.
Inhibitory effect of 10-hydroxy-trans-2-decenoic acid on LPS-induced IL-6 production via reducing IκB-ζ expression.
Innate Immun
2012
18:429-37
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Honda H, Nagai Y, Matsunaga T, Saitoh S, Akashi-Takamura S, Hayashi H, Fujii I, Miyake K, Muraguchi A, Takatsu K.
Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner.
J Leukoc Biol
2012
91(6):967-76
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Echigo R, Shimohata N, Karatsu K, Yano F, Kayasuga-Kariya Y, Fujisawa A, Ohto T, Kita Y, Nakamura M, Suzuki S, Mochizuki M, Shimizu T, Chung UI, Sasaki N.
Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage.
J Transl Med
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Takarada T, Takarada-Iemata M, Takahata Y, Yamada D, Yamamoto T, Nakamura Y, Hinoi E, Yoneda Y.
Osteoclastogenesis is negatively regulated by D-serine produced by osteoblasts.
J Cell Physiol
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227(10):3477-87
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Hiroyasu Tsutsuki, Kinnosuke Yahiro, Kotaro Suzuki, Akira Suto, Kohei Ogura, Sayaka Nagasawa, Hideshi Ihara, Takeshi Shimizu, Hiroshi Nakajima, Joel Moss, Masatoshi Noda
Subtilase Cytotoxin Enhances Escherichia Coli Survival in Macrophages by Suppression of Nitric Oxide Production Through the Inhibition of NF-κB Activation
Infect Immun
2012
80 (11), 3939-51
PubMed ID: 22949549
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Yoshikazu Morita, Aiko Ono-Ohmachi, Satoshi Higurashi, Hiroaki Matsuyama, Atsushi Serizawa, Tatsuo Takeya
The bone-strengthening activity of milk basic protein is not dependent on lactoferrin
International Dairy Journal
2012
27:40-46
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Toshiya KAWASAKI, Seiji GODA, Naoyuki MATSUMOTO
Effect of Akt on the Differentiation into Osteoclasts Caused by RANKL Stimulation
Journal of Oral Tissue Engineering
2012
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Iizuka M, Ayaori M, Uto-Kondo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Sasaki M, Komatsu T, Yogo M, Kishimoto Y, Kondo K, Ikewaki K.
Astaxanthin enhances ATP-binding cassette transporter A1/G1 expressions and cholesterol efflux from macrophages
J Nutr Sci Vitaminol (Tokyo)
2012
58(2):96-104
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Kakutani R, Adachi Y, Takata H, Kuriki T, Ohno N.
Essential role of Toll-like receptor 2 in macrophage activation by glycogen
Glycobiology
2012
22(1):146-59
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Miyashita K, Oyama T, Sakuta T, Tokuda M, Torii M.
Anandamide induces matrix metalloproteinase-2 production through cannabinoid-1 receptor and transient receptor potential vanilloid-1 in human dental pulp cells in culture
J Endod
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Yamamoto H, Abe Y, Miyazato A, Tanno D, Tanaka M, Miyasaka T, Ishii K, Kawakami K.
Cryptococcus neoformans suppresses the activation of bone marrow-derived dendritic cells stimulated with its own DNA, but not with DNA from other fungi.
FEMS Immunol. Med. Microbiol.
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Chen J, Qin S, Xiao J, Tanigawa S, Uto T, Hashimoto F, Fujii M, Hou DX.
A genome-wide microarray highlights the antiinflammatory genes targeted by oolong tea theasinensin A in macrophages.
Nutr Cancer
2011
63:1064-73
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Ozasa H, Ayaori M, Iizuka M, Terao Y, Uto-Kondo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Uehara Y, Ogura M, Sasaki M, Komatsu T, Horii S, Mochizuki S, Yoshimura M, Ikewaki K.
Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: findings from in vitro and ex vivo studies.
Atherosclerosis
2011
219:141-50
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Sakamoto T, Yamaguchi Y, Goto T, Takahashi N, Kawada T.
An in vitro analysis system using a fluorescence protein reporter for evaluating anti-inflammatory effects in macrophages.
Biosci. Biotechnol. Biochem.
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Itoh T, Hamada N, Terazawa R, Ito M, Ohno K, Ichihara M, Nozawa Y, Ito M.
Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.
Biochem. Biophys. Res. Commun.
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Fujimoto A, Akifusa S, Hirofuji T, Yamashita Y.
Involvement of suppressor of cytokine signaling-1 in globular adiponectin-induced granulocyte colony-stimulating factor in RAW 264 cell.
Mol. Immunol.
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Abiko Y, Miura T, Phuc BH, Shinkai Y, Kumagai Y.
Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole.
Toxicol. Appl. Pharmacol.
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Haque A, Noman AS, Koide N, Odkhuu E, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T.
An ADP ribosylation factor-GTPase activating protein negatively regulates the production of proinflammatory mediators in response to lipopolysaccharide.
Cancer Immunol. Immunother.
2011
60:1439-46
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Egusa H, Doi M, Saeki M, Fukuyasu S, Akashi Y, Yokota Y, Yatani H, Kamisaki Y.
The small molecule harmine regulates NFATc1 and Id2 expression in osteoclast progenitor cells.
Bone
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Akagi T, Shima F, Akashi M.
Intracellular degradation and distribution of protein-encapsulated amphiphilic poly(amino acid) nanoparticles.
Biomaterials
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Yamazaki Y, Kawano Y.
Inhibitory effects of herbal alkaloids on the tumor necrosis factor-α and nitric oxide production in lipopolysaccharide-stimulated RAW264 macrophages.
Chem. Pharm. Bull.
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Kurio N, Shimo T, Fukazawa T, Takaoka M, Okui T, Hassan NM, Honami T, Hatakeyama S, Ikeda M, Naomoto Y, Sasaki A.
Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo.
Exp. Cell Res.
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Arisaka M, Takano K, Negishi Y, Arima H, Aramaki Y.
Involvement of lipid rafts in macrophage apoptosis induced by cationic liposomes.
Arch. Biochem. Biophys.
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Ichioka M, Suganami T, Tsuda N, Shirakawa I, Hirata Y, Satoh-Asahara N, Shimoda Y, Tanaka M, Kim-Saijo M, Miyamoto Y, Kamei Y, Sata M, Ogawa Y.
Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans.
Diabetes
2011
60:819-26
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Haque A, Koide N, Iftakhar-E-Khuda I, Noman AS, Odkhuu E, Badamtseren B, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Flavopiridol inhibits lipopolysaccharide-induced TNF-α production through inactivation of nuclear factor-κB and mitogen-activated protein kinases in the MyD88-dependent pathway.
Microbiol. Immunol.
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Miyazaki T, Miyauchi S, Anada T, Imaizumi H, Suzuki O.
Evaluation of osteoclastic resorption activity using calcium phosphate coating combined with labeled polyanion.
Anal. Biochem.
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Yonezawa T, Hasegawa S, Asai M, Ninomiya T, Sasaki T, Cha BY, Teruya T, Ozawa H, Yagasaki K, Nagai K, Woo JT.
Harmine, a β-carboline alkaloid, inhibits osteoclast differentiation and bone resorption in vitro and in vivo.
Eur. J. Pharmacol.
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Kamio N, Akifusa S, Yamashita Y.
Diacylglycerol kinase alpha regulates globular adiponectin-induced reactive oxygen species.
Free Radic. Res.
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Fukata N, Uchida K, Kusuda T, Koyabu M, Miyoshi H, Fukui T, Matsushita M, Nishio A, Tabata Y, Okazaki K.
The effective therapy of cyclosporine A with drug delivery system in experimental colitis.
J Drug Target
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Tumurkhuu G, Koide N, Hiwasa T, Ookoshi M, Dagvadorj J, Abu Shadat Mohammod Noman, Iftakhar-E-Khuda I, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock.
Innate Immun
2011
17:97-105
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Shikama Y, Kuroishi T, Nagai Y, Iwakura Y, Shimauchi H, Takada H, Sugawara S, Endo Y.
Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).
Innate Immun
2011
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Oka H, Mori M, Kihara H.
F-spondin inhibits migration and differentiation of osteoclastic precursors
J Periodontol
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Oshima H, Popivanova BK, Oguma K, Kong D, Ishikawa TO, Oshima M.
Activation of epidermal growth factor receptor signaling by the prostaglandin E(2) receptor EP4 pathway during gastric tumorigenesis
Cancer Sci
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102(4):713-9
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Sugiyama K, Kawakami H, Kamata Y, Sugita-Konishi Y.
Effect of a combination of deoxynivalenol and nivalenol on lipopolisaccharide-induced nitric oxide production by mouse macrophages
Mycotoxin Res
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27(1):57-62
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Kizaki T, Maegawa T, Sakurai T, Ogasawara JE, Ookawara T, Oh-ishi S, Izawa T, Haga S, Ohno H.
Voluntary exercise attenuates obesity-associated inflammation through ghrelin expressed in macrophages
Biochem Biophys Res Commun
2011
413(3):454-9
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Terao Y, Ayaori M, Ogura M, Yakushiji E, Uto-Kondo H, Hisada T, Ozasa H, Takiguchi S, Nakaya K, Sasaki M, Komatsu T, Iizuka M, Horii S, Mochizuki S, Yoshimura M, Ikewaki K.
Effect of sulfonylurea agents on reverse cholesterol transport in vitro and vivo
J Atheroscler Thromb
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18(6):513-30
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Eisuke DOMAE, Yumiko OGAWA, Osamu TAKEUCHI, Yosuke UJII, Yu KATO, Toshiya KAWASAKI, Hiroshi HAYASHI, Reiko KOMASA, Naochika DOMAE, Seiji GODA, Takashi IKEO
The Effect of Lysenin on the Differentiation into Osteoclast Cells
Journal of Oral Tissue Engineering
2011
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Ishijima Y, Kawamura T, Kimura A, Kohno A, Okada T, Tsuji T, Watanabe Y.
Toll-like receptor 4-dependent adjuvant activity of Kakkon-to extract exists in the high molecular weight polysaccharide fraction
Int J Immunopathol Pharmacol
2011
24(1):43-54
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Mukai S, Kitazawa R, Ishii J, Kondo T, Hakozaki A, Horiuchi K, Haraguch R, Mori K, Kitazawa S.
Identification and analysis of function of a novel splicing variant of mouse receptor activator of NF-κB
Mol Cell Biochem
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350(1-2):29-38
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15355
Takayuki Anno, Keiichi Motoyama, Taishi Higashi, Fumitoshi Hirayama, Kaneto Uekama, Hidetoshi Arima
Preparation and evaluation of polyamidoamine dendrimer (G2)/branched-β-cyclodextrin conjugate as a novel gene transfer carrier
Journal of Inclusion Phenomena and Macrocyclic Chemistry
2011
70:339-344
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Cui H, Okuhira K, Ohoka N, Naito M, Kagechika H, Hirose A, Nishimaki-Mogami T.
Tributyltin chloride induces ABCA1 expression and apolipoprotein A-I-mediated cellular cholesterol efflux by activating LXRα/RXR
Biochem Pharmacol
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81(6):819-24
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15357
Di Guan, Zhenya Zhang, Yingnan Yang, Guoqing Xing, Jiqiang Liu
Immunomodulatory Activity of Polysaccharide from the Roots of Actinidia kolomikta on Macrophages
International Journal of Biology
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Aoyagi Y, Adachi Y, Ozawa K, Yokomizo C, Gui MY, Jin YR, Li XW, Ohno N, Takeya K.
Synthesis of rabdokunmin C analogues and their inhibitory effect on NF-κB activation
Bioorg Med Chem
2011
19(7):2450-7
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Hou DX, Masuzaki S, Tanigawa S, Hashimoto F, Chen J, Sogo T, Fujii M.
Oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (LPS)-activated mouse macrophages: structure-activity relationship and molecular mechanisms.
J. Agric. Food Chem.
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Oshima H, Hioki K, Popivanova BK, Oguma K, Van Rooijen N, Ishikawa TO, Oshima M.
Prostaglandin E? signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors.
Gastroenterology
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140:596-607.e7
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Ueda H, Ippoushi K, Takeuchi A.
Repeated oral administration of a squeezed ginger (Zingiber officinale) extract augmented the serum corticosterone level and had anti-inflammatory properties.
Biosci. Biotechnol. Biochem.
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Sakagami H, Zhou L, Kawano M, Thet MM, Tanaka S, Machino M, Amano S, Kuroshita R, Watanabe S, Chu Q, Wang QT, Kanamoto T, Terakubo S, Nakashima H, Sekine K, Shirataki Y, Zhang CH, Uesawa Y, Mohri K, Kitajima M, Oizumi H, Oizumi T.
Multiple biological complex of alkaline extract of the leaves of Sasa senanensis Rehder.
In Vivo
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24:735-43
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Lee JW, Mase N, Yonezawa T, Seo HJ, Jeon WB, Cha BY, Nagai K, Woo JT.
Palmatine attenuates osteoclast differentiation and function through inhibition of receptor activator of nuclear factor-κb ligand expression in osteoblast cells.
Biol. Pharm. Bull.
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Okui T, Shimo T, Fukazawa T, Kurio N, Hassan NM, Honami T, Takaoka M, Naomoto Y, Sasaki A.
Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction.
Mol. Cancer Ther.
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Shikama Y, Nagai Y, Okada S, Oizumi T, Shimauchi H, Sugawara S, Endo Y.
Pro-IL-1β accumulation in macrophages by alendronate and its prevention by clodronate.
Toxicol. Lett.
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Nakaya K, Ayaori M, Uto-Kondo H, Hisada T, Ogura M, Yakushiji E, Takiguchi S, Terao Y, Ozasa H, Sasaki M, Komatsu T, Ohsuzu F, Ikewaki K.
Cilostazol enhances macrophage reverse cholesterol transport in vitro and in vivo.
Atherosclerosis
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213:135-41
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Kotani H, Tanabe H, Mizukami H, Makishima M, Inoue M.
Identification of a naturally occurring rexinoid, honokiol, that activates the retinoid X receptor.
J. Nat. Prod.
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Yoshikawa K, Kokudo N, Hashimoto T, Yamamoto K, Inose T, Kimura T.
Novel phthalide compounds from Sparassis crispa (Hanabiratake), Hanabiratakelide A-C, exhibiting anti-cancer related activity.
Biol. Pharm. Bull.
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Nakatsuka R, Nozaki T, Shinohara M, Ohura K.
Dilazep decreases lipopolysaccharide-induced nitric oxide and TNF-alpha synthesis in RAW 264 cells.
J. Pharmacol. Sci.
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Yano H, Uchida M, Nakai R, Ishida K, Kato Y, Kawanishi N, Shiva D.
Exhaustive exercise reduces TNF-α and IFN-α production in response to R-848 via toll-like receptor 7 in mice.
Eur. J. Appl. Physiol.
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Shadat NM, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Retinoblastoma protein-interacting zinc finger 1 (RIZ1) regulates the proliferation of monocytic leukemia cells via activation of p53.
Cancer Invest.
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28:806-12
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Sakai H, Moriura Y, Notomi T, Kawawaki J, Ohnishi K, Kuno M.
Phospholipase C-dependent Ca2+-sensing pathways leading to endocytosis and inhibition of the plasma membrane vacuolar H+-ATPase in osteoclasts.
Am. J. Physiol., Cell Physiol.
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Yasuzaki Y, Yamada Y, Harashima H.
Mitochondrial matrix delivery using MITO-Porter, a liposome-based carrier that specifies fusion with mitochondrial membranes.
Biochem. Biophys. Res. Commun.
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Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nonaka K, Yamashita Y.
Involvement of the JAK-STAT pathway and SOCS3 in the regulation of adiponectin-generated reactive oxygen species in murine macrophage RAW 264 cells.
J. Cell. Biochem.
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Kato Y, Koide N, Komatsu T, Tumurkhuu G, Dagvadorj J, Kato K, Yokochi T.
Metformin attenuates production of nitric oxide in response to lipopolysaccharide by inhibiting MyD88-independent pathway.
Horm. Metab. Res.
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Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation.
Cell. Immunol.
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Ohata S, Moriyama C, Yamashita A, Nishida T, Kusumoto C, Mochida S, Minami Y, Nakada J, Shomori K, Inagaki Y, Ohta Y, Matsura T.
Polaprezinc Protects Mice against Endotoxin Shock.
J Clin Biochem Nutr
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Yamaguchi N, Hamachi T, Kamio N, Akifusa S, Masuda K, Nakamura Y, Nonaka K, Maeda K, Hanazawa S, Yamashita Y.
Expression levels of adiponectin receptors and periodontitis.
J. Periodont. Res.
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Xiao G, Miyazato A, Abe Y, Zhang T, Nakamura K, Inden K, Tanaka M, Tanno D, Miyasaka T, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Yamamoto N, Kunishima H, Hirakata Y, Kaku M, Kawakami K.
Activation of myeloid dendritic cells by deoxynucleic acids from Cordyceps sinensis via a Toll-like receptor 9-dependent pathway.
Cell. Immunol.
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Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Retinoblastoma protein-interacting zinc finger 1 (RIZ1) participates in RANKL-induced osteoclast formation via regulation of NFATc1 expression.
Immunol. Lett.
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Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS.
Immunology
2010
131:59-66
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Kitagawa Y, Tohya Y, Ike F, Kajita A, Park SJ, Ishii Y, Kyuwa S, Yoshikawa Y.
Indirect ELISA and indirect immunofluorescent antibody assay for detecting the antibody against murine norovirus S7 in mice.
Exp. Anim.
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59:47-55
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Shimoda H, Shan SJ, Tanaka J, Seki A, Seo JW, Kasajima N, Tamura S, Ke Y, Murakami N.
Anti-inflammatory properties of red ginger (Zingiber officinale var. Rubra) extract and suppression of nitric oxide production by its constituents.
J Med Food
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Tsukamoto H, Fukudome K, Takao S, Tsuneyoshi N, Kimoto M.
Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.
Int. Immunol.
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Arisaka M, Nakamura T, Yamada A, Negishi Y, Aramaki Y.
Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells.
FEBS Lett.
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Hakozaki A, Yoda M, Tohmonda T, Furukawa M, Hikata T, Uchikawa S, Takaishi H, Matsumoto M, Chiba K, Horiuchi K, Toyama Y.
Receptor activator of NF-kappaB (RANK) ligand induces ectodomain shedding of RANK in murine RAW264.7 macrophages.
J. Immunol.
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Suzuki T, Chang MO, Kitajima M, Takaku H.
Baculovirus activates murine dendritic cells and induces non-specific NK cell and T cell immune responses.
Cell. Immunol.
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Hirai S, Uemura T, Mizoguchi N, Lee JY, Taketani K, Nakano Y, Hoshino S, Tsuge N, Narukami T, Yu R, Takahashi N, Kawada T.
Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages.
Mol Nutr Food Res
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54:797-804
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Fujimoto A, Akifusa S, Kamio N, Hirofuji T, Nonaka K, Yamashita Y.
Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species.
Free Radic. Res.
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Matsubara T, Ikeda F, Hata K, Nakanishi M, Okada M, Yasuda H, Nishimura R, Yoneda T.
Cbp recruitment of Csk into lipid rafts is critical to c-Src kinase activity and bone resorption in osteoclasts.
J. Bone Miner. Res.
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Sugiyama K, Muroi M, Tanamoto K, Nishijima M, Sugita-Konishi Y.
Deoxynivalenol and nivalenol inhibit lipopolysaccharide-induced nitric oxide production by mouse macrophage cells.
Toxicol. Lett.
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Kishimoto Y, Tani M, Uto-Kondo H, Iizuka M, Saita E, Sone H, Kurata H, Kondo K.
Astaxanthin suppresses scavenger receptor expression and matrix metalloproteinase activity in macrophages.
Eur J Nutr
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Chen J, Uto T, Tanigawa S, Yamada-Kato T, Fujii M, Hou DX.
Microarray-based determination of anti-inflammatory genes targeted by 6-(methylsulfinyl)hexyl isothiocyanate in macrophages.
Exp Ther Med
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Kaori Yoshino, Kaoru Saijo, Chikako Noro and Yukio Nakamura
Development of a simple method to determine the mouse strain from which cultured cell lines originated
Interdisciplinary Bio Central
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Miyazaki T, Miyauchi S, Tawada A, Anada T, Suzuki O.
Effect of chondroitin sulfate-E on the osteoclastic differentiation of RAW264 cells.
Dent Mater J
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29(4):403-10
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Uto T, Suangkaew N, Morinaga O, Kariyazono H, Oiso S, Shoyama Y.
Eriobotryae folium extract suppresses LPS-induced iNOS and COX-2 expression by inhibition of NF-kappaB and MAPK activation in murine macrophages
Am J Chin Med
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38(5):985-94
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Sasaki M, Miyakoshi M, Sato Y, Nakanuma Y.
Modulation of the microenvironment by senescent biliary epithelial cells may be involved in the pathogenesis of primary biliary cirrhosis
J Hepatol
2010
53(2):318-25
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B. Sritularak, A. Tantituvanont1, P. Chanvorachote1, K. Meksawan1, T. Miyamoto2, Y. Kohno and K. Likhitwitayawuid
Flavonoids with free radical scavenging activity and nitric oxide inhibitory effect from the stem bark of Artocarpus gomezianus
Journal of Medicinal Plants Research
2010
4:387-392
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Takeichi SAKATA, Seiji GODA, Yumiko OGAWA, Takashi IKEO, Shosuke MORITA
β1-Integrin-Dependent Macrophage Migration is Regulated by MAP Kinase
Journal of Oral Tissue Engineering
2010
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Tanikawa T, Kitamura M, Hayashi Y, Tomida N, Uwaya A, Isami F, Inoue Y.
Anti-Inflammatory Effects of Morinda citrifolia Extract against Lipopolysaccharide-Induced Inflammation in RAW264 Cells
Medicines (Basel)
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Lee JW, Ahn JY, Hasegawa S, Cha BY, Yonezawa T, Nagai K, Seo HJ, Jeon WB, Woo JT.
Inhibitory effect of luteolin on osteoclast differentiation and function.
Cytotechnology
2009
61:125-34
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Katsuura S, Imamura T, Bando N, Yamanishi R.
beta-Carotene and beta-cryptoxanthin but not lutein evoke redox and immune changes in RAW264 murine macrophages.
Mol Nutr Food Res
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53:1396-405
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Shioiri T, Muroi M, Hatao F, Nishida M, Ogawa T, Mimura Y, Seto Y, Kaminishi M, Tanamoto K.
Caspase-3 is activated and rapidly released from human umbilical vein endothelial cells in response to lipopolysaccharide.
Biochim. Biophys. Acta
2009
1792:1011-8
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Kamio N, Akifusa S, Yamaguchi N, Nonaka K, Yamashita Y.
Anti-inflammatory activity of a globular adiponectin function on RAW 264 cells stimulated by lipopolysaccharide from Aggregatibacter actinomycetemcomitans.
FEMS Immunol. Med. Microbiol.
2009
56:241-7
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Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Thalidomide inhibits lipopolysaccharide-induced nitric oxide production and prevents lipopolysaccharide-mediated lethality in mice.
FEMS Immunol. Med. Microbiol.
2009
56:204-11
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Miyazato A, Nakamura K, Yamamoto N, Mora-Montes HM, Tanaka M, Abe Y, Tanno D, Inden K, Gang X, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Mitsutake K, Gow NA, Kaku M, Kawakami K.
Toll-like receptor 9-dependent activation of myeloid dendritic cells by Deoxynucleic acids from Candida albicans.
Infect. Immun.
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Seddek Al, Mahmoud ME, Shiina T, Hirayama H, Iwami M, Miyazawa S, Nikami H, Takewaki T, Shimizu Y.
Extract from Calotropis procera latex activates murine macrophages.
J Nat Med
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63:297-303
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Tomimori Y, Mori K, Koide M, Nakamichi Y, Ninomiya T, Udagawa N, Yasuda H.
Evaluation of pharmaceuticals with a novel 50-hour animal model of bone loss.
J. Bone Miner. Res.
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Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nishihara T, Yamashita Y.
Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2.
Free Radic. Biol. Med.
2009
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Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y.
Involvement of Ca(2+) in globular adiponectin-induced reactive oxygen species.
Biochem. Biophys. Res. Commun.
2009
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Hassan F, Islam S, Tumurkhuu G, Dagvadorj J, Naiki Y, Komatsu T, Koide N, Yoshida T, Yokochi T.
Involvement of interleukin-1 receptor-associated kinase (IRAK)-M in toll-like receptor (TLR) 7-mediated tolerance in RAW 264.7 macrophage-like cells.
Cell. Immunol.
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Kasugai C, Morikawa A, Naiki Y, Koide N, Komatsu T, Yoshida T, Yokochi T.
Concanavalin A induces formation of osteoclast-like cells in RAW 264.7 mouse macrophage cells.
Immunopharmacol Immunotoxicol
2009
31:103-7
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Iftakhar-E-Khuda I, Koide N, Hassan F, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Novel mechanism of U18666A-induced tumour necrosis factor-alpha production in RAW 264.7 macrophage cells.
Clin. Exp. Immunol.
2009
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Noman AS, Koide N, Hassan F, I-E-Khuda I, Dagvadorj J, Tumurkhuu G, Islam S, Naiki Y, Yoshida T, Yokochi T.
Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression.
Innate Immun
2009
15:33-41
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Inden K, Kaneko J, Miyazato A, Yamamoto N, Mouri S, Shibuya Y, Nakamura K, Aoyagi T, Hatta M, Kunishima H, Hirakata Y, Itoh Y, Kaku M, Kawakami K.
Toll-like receptor 4-dependent activation of myeloid dendritic cells by leukocidin of Staphylococcus aureus.
Microbes Infect.
2009
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Nakamura T, Kodama N, Arai Y, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ishikawa T, Ueno K, Yano S.
Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7.
J Nat Med
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63:21-7
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Nakamura T, Kodama N, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ueno K, Ishikawa T, Yano S.
Inhibitory effect of the extracts from Thai medicinal plants on iNOS expression in mouse macrophage RAW 264.7.
J Nat Med
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Nakamura T, Kodama N, Oda M, Tsuchiya S, Arai Y, Kumamoto T, Ishikawa T, Ueno K, Yano S.
The structure-activity relationship between oxycoumarin derivatives showing inhibitory effects on iNOS in mouse macrophage RAW264.7 cells.
J Nat Med
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Murakami M, Kawachi H, Ogawa K, Nishino Y, Funaba M.
Receptor expression modulates the specificity of transforming growth factor-beta signaling pathways.
Genes Cells
2009
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Tsuji M, Yamamoto H, Sato T, Mizuha Y, Kawai Y, Taketani Y, Kato S, Terao J, Inakuma T, Takeda E.
Dietary quercetin inhibits bone loss without effect on the uterus in ovariectomized mice.
J Bone Miner Metab
2009
27(6):673-81
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Masayuki TAIRA et al
DNA Microarray Analyses of the Effects of LPS-stimulation and IC50 Nickel Ions on Gene Expressions of Mouse Macrophage-like Cell Line RAW264
Nano Biomedicine
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Ken Shirato, Takako Kizaki, Takuya Sakurai, Jun-Etsu Ogasawara, Yoshinaga Ishibashi, Takehiko Iijima, Chikako Okada, Izumi Noguchi, Kazuhiko Imaizumi, Naoyuki Taniguchi, Hideki Ohno
Hypoxia-inducible factor-1alpha suppresses the expression of macrophage scavenger receptor 1
Pflugers Arch
2009
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Namba T, Tanaka K, Ito Y, Ishihara T, Hoshino T, Gotoh T, Endo M, Sato K, Mizushima T.
Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis
Am J Pathol
2009
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Iigo M, Alexander DB, Long N, Xu J, Fukamachi K, Futakuchi M, Takase M, Tsuda H.
Anticarcinogenesis pathways activated by bovine lactoferrin in the murine small intestine
Biochimie
2009
91(1):86-101
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Aoyama T, Takeshita K, Kikuchi R, Yamamoto K, Cheng XW, Liao JK, Murohara T.
gamma-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice
Biochem Biophys Res Commun
2009
383(2):216-21
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Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y.
Regulation of globular adiponectin-induced apoptosis by reactive oxygen/nitrogen species in RAW264 macrophages.
Free Radic. Biol. Med.
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Yoshida H, Kwon AH, Habara K, Yamada M, Kaibori M, Kamiyama Y, Nishizawa M, Ito S, Okumura T.
Edaravone inhibits the induction of iNOS gene expression at transcriptional and posttranscriptional steps in murine macrophages.
Shock
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Nishida K, Kuchiiwa S, Oiso S, Futagawa T, Masuda S, Takeda Y, Yamada K.
Up-regulation of matrix metalloproteinase-3 in the dorsal root ganglion of rats with paclitaxel-induced neuropathy.
Cancer Sci
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Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs.
Biochem Biophys Res Commun
2008
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Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H.
Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9.
J Biol Chem
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Expression and function of alternative splice variants of the mouse TGF-beta type I receptor
Cell Biol Int
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Kawanishi N, Tanaka Y, Kato Y, Shiva D, Yano H.
Lipopolysaccharide-induced monocyte chemotactic protein-1 is enhanced by suppression of nitric oxide production, which depends on poor CD14 expression on the surface of skeletal muscle
Cell Biochem Funct
2008
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Ishii J, Kitazawa R, Mori K, McHugh KP, Morii E, Kondo T, Kitazawa S.
Lipopolysaccharide suppresses RANK gene expression in macrophages by down-regulating PU.1 and MITF
J Cell Biochem
2008
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15373
Yumiko Ogawa, Seiji Goda, Shosuke Morita
The Effect of Methyl-β-cyclodextrin on the Differentiation of RAW264 Cells into Osteoclasts
Oral Science International
2008
5:15-23
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15375
Ken-ichiro Minato
Immunomodulation Activity of a Polysaccharide Fraction of a Culinary-Medicinal Mushroom, Pleurotus citrinopileatus Singer (Agaricomycetideae), in Vitro
International Journal of Medicinal Mushrooms
2008
10:235-244
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15376
Oguma K, Oshima H, Aoki M, Uchio R, Naka K, Nakamura S, Hirao A, Saya H, Taketo MM, Oshima M.
Activated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells
EMBO J
2008
27(12):1671-81
PubMed ID: 18511911
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15377
Ryo Kakutani, Yoshiyuki Adachi, Hideki Kajiura, Hiroki Takata, Naohito Ohno, Takashi Kuriki
Stimulation of macrophage by enzymatically synthesized glycogen: the relationship between structure and biological activity
Biocatalysis and Biotransformation
2008
26:152-160
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8815
Taira M, Sasaki K, Saitoh S, Nezu T, Sasaki M, Kimura S, Terasaki K, Sera K, Narushima T, Araki Y.
Accumulation of element Ti in macrophage-like RAW264 cells cultured in medium with 1 ppm Ti and effects on cell viability, SOD production and TNF-alpha secretion.
Dent Mater J
2007
25:726-32
PubMed ID: 17338307
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8850
Yamaguchi N, Kukita T, Li YJ, Martinez Argueta JG, Saito T, Hanazawa S, Yamashita Y.
Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.
FEMS Immunol. Med. Microbiol.
2007
49:28-34
PubMed ID: 17094790
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4889
Takayoshi Suganami, Kanami Tanimoto-Koyama, Junko Nishida, Michiko Itoh, Xunmei Yuan, Shinji Mizuarai, Hidehito Kotani, Shoji Yamaoka, Kensuke Miyake, Seiichiro Aoe, Yasutomi Kamei and Yoshihiro Ogawa
Role of the Toll-like Receptor 4/NF-κB Pathway in Saturated Fatty Acid−Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages
Arterioscler Thromb Vasc Biol
2007
27:84-91
PubMed ID: 17082484
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7269
Takarada T, Hinoi E, Kambe Y, Sahara K, Kurokawa S, Takahata Y, Yoneda Y.
Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative cytotoxicity of ascorbic acid.
Eur J Pharmacol
2007
575(1-3):1-11
PubMed ID: 17698058
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7349
Ito M, Haito S, Furumoto M, Uehata Y, Sakurai A, Segawa H, Tatsumi S, Kuwahata M, Miyamoto K.
Unique uptake and efflux systems of inorganic phosphate in osteoclast-like cells.
Am J Physiol Cell Physiol
2007
292(1):C526-34
PubMed ID: 16971494
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7387
Murakami Y, Hirata A, Ito S, Shoji M, Tanaka S, Yasui T, Machino M, Fujisawa S.
Re-evaluation of cyclooxygenase-2-inhibiting activity of vanillin and guaiacol in macrophages stimulated with lipopolysaccharide.
Anticancer Res
2007
27(2):801-7
PubMed ID: 17465205
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10072
Yoshinari Uehara 1, Shin-ichiro Miura, Arnold von Eckardstein, Satomi Abe, Akihiro Fujii, Yoshino Matsuo, Stephan Rust, Stefan Lorkowski, Gerd Assmann, Tatsuo Yamada, Keijiro Saku
Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element
Atherosclerosis
2007
191(1):11-21
PubMed ID: 16730733
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12814
Uto T, Fujii M, Hou DX.
Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-gamma and 12-O-tetradecanoylphorbol-13-acetate
Oncol Rep
2007
17(1):233-8
PubMed ID: 17143503
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15374
Natalie Ohashi, Miho Nakamura, Akiko Nagai, Yumi Tanaka, Yasutaka Sekijima, Kimihiro Yamashita
Comparison of Hydroxyapatite with Carbonate Apatite in Osteoclastic Cell Resorptive Activity
Key Engineering Materials
2007
361-363:1039-1042
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15378
Yuki Kaneshita, Seiji Goda, Tatsuo Kawamoto
The effect of matrix metalloproteinase-9 on the differentiation into osteoclast cells on RAW264 cells
Orthodontic Waves
2007
66:122-128
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15379
Kentaro Harutsugu, Kyoko Watanabe, Michiharu Daito
The role of anti immune response on adenosine stimulated macrophages
Pediatric Dental Journal
2007
1:40-46
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15642
Junji TANAKA, Shao-Jie SHAN, Naoki KASAJIMA, Hiroshi SHIMODA
Suppressive Effect of Defatted Kiwi Fruit Seed Extract on Acute Inflammation and Skin Pigmentation
Food Science and Technology Research
2007
13:310-314
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8917
Soji Fukumoto, Paramasari Dirgahayu, Kozue Nunomura, Haruyo Matsuura andKazumitsu Hirai
Suppression of LPS-induced Cyclooxygenase-2 (cox-2) Gene Expression in Mouse Macrophages by Excretory/Secretory Products of Spirometra erinaceieuropaei Plerocercoids
Yonago Acta Med.
2006
49:39-47
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6489
Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A.
TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.
Arthritis Res Ther
2006
8(5):R146
PubMed ID: 16945157
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6976
Nagai N, Anzawa T, Satoh Y, Suzuki T, Tajima K, Munekata M.
Activities of MC3T3-E1 cells cultured on gamma-irradiated salmon atelocollagen scaffold.
J Biosci Bioeng
2006
101(6):511-4
PubMed ID: 16935254
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7020
Murakami Y, Shoji M, Ogiwara T, Tanaka S, Yokoe I, Fujisawa S.
Preventive effect of ortho dimer of butylated hydroxyanisole on activator protein-1 activation and cyclooxygenase-2 expression in macrophages stimulated by fimbriae of Porphyromonas gingivalis, an oral anaerobe.
Anticancer Res
2006
26(4B):2915-20
PubMed ID: 16886613
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7039
Funaba M, Nakaya K, Ikeda T, Murakami M, Tsuchida K, Sugino H.
Requirement of Smad3 for mast cell growth.
Cell Immunol
2006
240(1):47-52
PubMed ID: 16839529
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13660
Kimura Y, Sumiyoshi M, Suzuki T, Sakanaka M.
Antitumor and antimetastatic activity of a novel water-soluble low molecular weight beta-1, 3-D-glucan (branch beta-1,6) isolated from Aureobasidium pullulans 1A1 strain black yeast
Anticancer Res
2006
26(6B):4131-41
PubMed ID: 17201124
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13729
Imamura T, Bando N, Yamanishi R.
Beta-carotene modulates the immunological function of RAW264, a murine macrophage cell line, by enhancing the level of intracellular glutathione
Biosci Biotechnol Biochem
2006
70(9):2112-20.
PubMed ID: 16960387
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15371
Suzuki N, Yoshimura Y, Deyama Y, Suzuki K, Kitagawa Y.
Mechanical stress directly suppresses osteoclast differentiation in RAW264.7 cells
Int J Mol Med
2006
21(3):291-6
PubMed ID: 18288375
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15381
KYOKO WATANABE, SHINYA SHIRASU, KIYOSHI DAITO, MASAHARU MOTOYAMA, YOSHITOMO OGAWA, KOJI NAKAI, KIYOSHI OHURA, MICHIHARU DAITO
Differentiation of the expression of A2a adenosine receptor in macrophage cell lines RAW264
ORAL THERAPEUTICS AND PHARMACOLOGY
2006
25:8-16
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15382
Hida S, Nagi-Miura N, Adachi Y, Ohno N.
Beta-glucan derived from zymosan acts as an adjuvant for collagen-induced arthritis
Microbiol Immunol
2006
50(6):453-61
PubMed ID: 16785717
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15383
Casolaro M, Bottari S, Ito Y.
Vinyl polymers based on L-histidine residues. Part 2. Swelling and electric behavior of smart poly(ampholyte) hydrogels for biomedical applications
Biomacromolecules
2006
;7(5):1439-48
PubMed ID: 16677025
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15384
Funaba M, Murakami M, Ikeda T, Ogawa K, Tsuchida K, Sugino H.
Identification of tocopherol-associated protein as an activin/TGF-beta-inducible gene in mast cells
Biochim Biophys Acta
2006
1763(8):900-6
PubMed ID: 16872693
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3160
Wei, Ping, Taniguchi, Susumu, Sakai, Yoshiyuki, Imamura, Minako, Inoguchi, Toyoshi, Nawata, Hajime, Oda, Shinya, Nakabeppu, Yusaku, Nishimura, Junji, Ikuyama, Shoichiro
Expression of adipose differentiation-related protein (ADRP) is conjointly regulated by PU.1 and AP-1 in macrophages.
J Biochem
2005
138:399-412
PubMed ID: 16272134
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2903
Shimomura-Shimizu M, Sugiyama K, Muroi M, Tanamoto K
Alachlor and carbaryl suppress lipopolysaccharide-induced iNOS expression by differentially inhibiting NF-kappaB activation.
Biochem Biophys Res Commun
2005
332:793-9
PubMed ID: 15907790
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2922
Musikacharoen, Tipayaratn, Oguma, Asako, Yoshikai, Yasunobu, Chiba, Norika, Masuda, Akio, Matsuguchi, Tetsuya
Interleukin-15 induces IL-12 receptor beta1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling.
Blood
2005
105:711-20
PubMed ID: 15345588
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3365
Ito, Mikiko, Matsuka, Naoko, Izuka, Michiyo, Haito, Sakiko, Sakai, Yuko, Nakamura, Rie, Segawa, Hiroko, Kuwahata, Masashi, Yamamoto, Hironori, Pike, Wesley J, Miyamoto, Ken-ichi
Characterization of inorganic phosphate transport in osteoclast-like cells.
Am J Physiol Cell Physiol
2005
288:C921-31
PubMed ID: 15601753
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3392
Aki, Daisuke, Mashima, Ryuichi, Saeki, Kazuko, Minoda, Yasumasa, Yamauchi, Moriyasu, Yoshimura, Akihiko
Modulation of TLR signalling by the C-terminal Src kinase (Csk) in macrophages.
Genes Cells
2005
10:357-68
PubMed ID: 15773898
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3210
Hou, De-Xing, Yanagita, Takashi, Uto, Takuhiro, Masuzaki, Satoko, Fujii, Makoto
Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved.
Biochem Pharmacol
2005
70:417-25
PubMed ID: 15963474
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3190
Hassan, Ferdaus, Islam, Shamima, Mu, Mya Mya, Ito, Hiroyasu, Koide, Naoki, Mori, Isamu, Yoshida, Tomoaki, Yokochi, Takashi
Lipopolysaccharide prevents doxorubicin-induced apoptosis in RAW 264.7 macrophage cells by inhibiting p53 activation.
Mol Cancer Res
2005
3:373-9
PubMed ID: 16046548
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3098
Suganami, Takayoshi, Nishida, Junko, Ogawa, Yoshihiro
A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha.
Arterioscler Thromb Vasc Biol
2005
25:2062-2068
PubMed ID: 16123319
|
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3209
Uto, Takuhiro, Fujii, Makoto, Hou, De-Xing
6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages.
Biochem Pharmacol
2005
70:1211-21
PubMed ID: 16139249
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9122
Kobayashi Y, Mizoguchi T, Take I, Kurihara S, Udagawa N, Takahashi N.
Prostaglandin E2 enhances osteoclastic differentiation of precursor cells through protein kinase A-dependent phosphorylation of TAK1.
J. Biol. Chem.
2005
280:11395-403
PubMed ID: 15647289
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2919
Abe T, Hemmi H, Miyamoto H, Moriishi K, Tamura S, Takaku H, Akira S, Matsuura Y.
Involvement of the Toll-like receptor 9 signaling pathway in the induction of innate immunity by baculovirus.
J Virol
2005
79(5):2847-58
PubMed ID: 15709004
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5921
Uto T, Fujii M, Hou DX.
Inhibition of lipopolysaccharide-induced cyclooxygenase-2 transcription by 6-(methylsulfinyl) hexyl isothiocyanate, a chemopreventive compound from Wasabia japonica (Miq.) Matsumura, in mouse macrophages.
Biochem Pharmacol
2005
70(12):1772-84
PubMed ID: 16256955
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6868
Hirata A, Murakami Y, Atsumi T, Shoji M, Ogiwara T, Shibuya K, Ito S, Yokoe I, Fujisawa S.
Ferulic acid dimer inhibits lipopolysaccharide-stimulated cyclooxygenase-2 expression in macrophages.
In Vivo
2005
19(5):849-53
PubMed ID: 16097437
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6869
Hirata A, Murakami Y, Shoji M, Kadoma Y, Fujisawa S.
Kinetics of radical-scavenging activity of hesperetin and hesperidin and their inhibitory activity on COX-2 expression.
Anticancer Res
2005
25(5):3367-74
PubMed ID: 16101151
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6873
Murakami Y, Ito S, Atsumi T, Fujisawa S.
Theoretical prediction of the relationship between phenol function and COX-2/AP-1 inhibition for ferulic acid-related compounds.
In Vivo
2005
19(6):1039-43
PubMed ID: 16277019
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6874
Okada N, Hirata A, Murakami Y, Shoji M, Sakagami H, Fujisawa S.
Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression by eugenol-related compounds.
Anticancer Res
2005
25(5):3263-9
PubMed ID: 16101137
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12262
Tomohiro Konno, Hirokazu Hasuda, Kazuhiko Ishihara, Yoshihiro Ito
Photo-immobilization of a phospholipid polymer for surface modification
Biomaterials
2005
26(12):1381-8
PubMed ID: 15482825
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12263
Hirokazu Hasuda , Oh Hyeong Kwon, Inn-Kyu Kang, Yoshihiro Ito
Synthesis of photoreactive pullulan for surface modification
Biomaterials
2005
26(15):2401-6
PubMed ID: 15585243
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15385
Kyoko Watanabe
Differentiation by LPS and IFN-γ of expression of adenosine receptors in macrophage cell lines RAW264 and J774
Pediatric Dental Journal
2005
15:43-51
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15386
Koji Tatebayashi, Eiko Matsui, Hideo Kaneko, Toshiyuki Fukao, Kimiko Kasahara, Naomi Kondo
IL-12B Promoter Polymorphism Associated with Asthma and IL-12B Transcriptional Activity
Allergology International
2005
54:451-459
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15387
Kurozumi R, Takahashi M, Kojima S.
Involvement of mitochondrial peroxynitrite in nitric oxide-induced glutathione synthesis
Biol Pharm Bull
2005
28(5):779-85
PubMed ID: 15863878
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15388
Mario Casolaro, Eugenio Paccagnini, Raniero Mendichi, Yoshihiro Ito
Stimuli-Responsive Polymers Based on l-Phenylalanine Residues: Protonation Thermodynamics of Free Polymers and Cross-Linked Hydrogels
Macromolecules
2005
38:2460-2468
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15389
Hatao F, Hiki N, Mimura Y, Ogawa T, Kojima J, Mafune K, Hawkins LD, Muroi M, Tanamoto K, Kaminishi M.
The induction of super-resistance using synthetic lipopolysaccharide receptor agonist rescues fatal endotoxemia in rats without excessive immunosuppression
Shock
2005
23(4):365-70
PubMed ID: 15803061
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2890
Ito T, Morimatsu M, Oonuma T, Shiina T, Kitamura H, Syuto B
Transcriptional regulation of the MAIL gene in LPS-stimulated RAW264 mouse macrophages.
Gene
2004
342:137-43
PubMed ID: 15527973
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2904
Itoh CE, Kizaki T, Hitomi Y, Hanawa T, Kamiya S, Ookawara T, Suzuki K, Izawa T, Saitoh D, Haga S, Ohno H
Down-regulation of beta2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation.
Biochem Biophys Res Commun
2004
322:979-84
PubMed ID: 15336560
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3200
Suzuki, Shogo, Nishimaki-Mogami, Tomoko, Tamehiro, Norimasa, Inoue, Kazuhide, Arakawa, Reijiro, Abe-Dohmae, Sumiko, Tanaka, Arowu R, Ueda, Kazumitsu, Yokoyama, Shinji
Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism.
Arterioscler Thromb Vasc Biol
2004
24:519-25
PubMed ID: 14726413
|
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3229
Okuhira, Kei-ichiro, Tsujita, Maki, Yamauchi, Yoshio, Abe-Dohmae, Sumiko, Kato, Koichi, Handa, Tetsurou, Yokoyama, Shinji
Potential involvement of dissociated apoA-I in the ABCA1-dependent cellular lipid release by HDL.
J Lipid Res
2004
45:645-52
PubMed ID: 14729855
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3193
Ban, Hyun Seung, Suzuki, Katsuya, Lim, Soon Sung, Jung, Sang Hoon, Lee, Sanghyun, Ji, Jun, Lee, Hye Seung, Lee, Yeon Sil, Shin, Kuk Hyun, Ohuchi, Kazuo
Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by 2'-hydroxychalcone derivatives in RAW 264.7 cells.
Biochem Pharmacol
2004
67:1549-57
PubMed ID: 15041472
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3212
Kato, Sawako, Yuzawa, Yukio, Tsuboi, Naotake, Maruyama, Shoichi, Morita, Yoshiki, Matsuguchi, Tetsuya, Matsuo, Seiichi
Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4.
J Am Soc Nephrol
2004
15:1289-99
PubMed ID: 15100369
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2688
Takahashi, Tetsuyuki, Takasuka, Nobuo, Iigo, Masaaki, Baba, Masaki, Nishino, Hoyoku, Tsuda, Hiroyuki, Okuyama, Toru
Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development.
Cancer Sci
2004
95:448-53
PubMed ID: 15132774
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3220
Adachi, Yoshiyuki, Ishii, Takashi, Ikeda, Yoshihiko, Hoshino, Akiyoshi, Tamura, Hiroshi, Aketagawa, Jun, Tanaka, Shigenori, Ohno, Naohito
Characterization of beta-glucan recognition site on C-type lectin, dectin 1.
Infect Immun
2004
72:4159-71
PubMed ID: 15213161
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3364
Hatao, Fumihiko, Muroi, Masashi, Hiki, Naoki, Ogawa, Toshihisa, Mimura, Yoshikazu, Kaminishi, Michio, Tanamoto, Ken-ichi
Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein.
J Leukoc Biol
2004
76:904-8
PubMed ID: 15258191
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3197
Matsumoto, Masahito, Kogawa, Masakazu, Wada, Seiki, Takayanagi, Hiroshi, Tsujimoto, Masafumi, Katayama, Shigehiro, Hisatake, Koji, Nogi, Yasuhisa
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1.
J Biol Chem
2004
279:45969-79
PubMed ID: 15304486
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2865
Ikeda, Fumiyo, Nishimura, Riko, Matsubara, Takuma, Tanaka, Sakae, Inoue, Jun-ichiro, Reddy, Sakamuri V, Hata, Kenji, Yamashita, Kenji, Hiraga, Toru, Watanabe, Toshiyuki, Kukita, Toshio, Yoshioka, Katsuji, Rao, Anjana, Yoneda, Toshiyuki
Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation.
J Clin Invest
2004
114:475-84
PubMed ID: 15314684
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3135
Kimura T. et al.
Novel PVA-DNA nanoparticles prepared by ultra high pressure technology for gene delivery.
Materials Science and Engineering C
2004
24:797-801
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6477
Ogasawara T, Katagiri M, Yamamoto A, Hoshi K, Takato T, Nakamura K, Tanaka S, Okayama H, Kawaguchi H.
Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).
J Bone Miner Res
2004
19(7):1128-36
PubMed ID: 15176996
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6737
Naruse M, Otsuka E, Naruse M, Ishihara Y, Miyagawa-Tomita S, Hagiwara H.
Inhibition of osteoclast formation by 3-methylcholanthrene, a ligand for arylhydrocarbon receptor: suppression of osteoclast differentiation factor in osteogenic cells.
Biochem Pharmacol
2004
67(1):119-27
PubMed ID: 14667934
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13881
Sato A, Keng VW, Yamamoto T, Kasamatsu S, Ban T, Tanaka H, Satoh S, Yamada K, Noguchi T.
Identification and characterization of the hematopoietic cell-specific enhancer-like element of the mouse hex gene
J Biochem
2004
135(2):259-68
PubMed ID: 15047729
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14419
Nakamichi K, Inoue S, Takasaki T, Morimoto K, Kurane I.
Rabies virus stimulates nitric oxide production and CXC chemokine ligand 10 expression in macrophages through activation of extracellular signal-regulated kinases 1 and 2
J Virol
2004
78(17):9376-88
PubMed ID: 15308732
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6705
Murakami Y, Shoji M, Hanazawa S, Tanaka S, Fujisawa S.
Preventive effect of bis-eugenol, a eugenol ortho dimer, on lipopolysaccharide-stimulated nuclear factor kappa B activation and inflammatory cytokine expression in macrophages.
Biochem Pharmacol
2003
66(6):1061-6
PubMed ID: 12963494
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15298
Kyoko Watanabe, Yasutaka Azuma, Shinya Shirasu, Michiharu Daito, Kiyoshi Ohura
Alteration of the Expression of A 2 a Adenosine Receptor and Toll-like Receptor 4 in Macrophage Cell Lines.
Japanese Journal of Oral Biology
2003
45:437-444
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2664
Kizaki, Takako, Suzuki, Kenji, Hitomi, Yoshiaki, Taniguchi, Naoyuki, Saitoh, Daizoh, Watanabe, Kenji, Onoe, Kazunori, Day, Noorbibi K, Good, Robert A, Ohno, Hideki
Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages.
Proc Natl Acad Sci U S A
2002
99:9392-7
PubMed ID: 12089332
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2654
Muroi, Masashi, Tanamoto, Ken-Ichi
The polysaccharide portion plays an indispensable role in Salmonella lipopolysaccharide-induced activation of NF-kappaB through human toll-like receptor 4.
Infect Immun
2002
70:6043-7
PubMed ID: 12379680
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2521
Kinjyo I, Hanada T, Inagaki-Ohara K, Mori H, Aki D, Ohishi M, Yoshida H, Kubo M, Yoshimura A.
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation.
Immunity
2002
17(5):583-91
PubMed ID: 12433365
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2529
Yamamoto A, Miyazaki T, Kadono Y, Takayanagi H, Miura T, Nishina H, Katada T, Wakabayashi K, Oda H, Nakamura K, Tanaka S.
Possible involvement of IkappaB kinase 2 and MKK7 in osteoclastogenesis induced by receptor activator of nuclear factor kappaB ligand.
J Bone Miner Res
2002
17(4):612-21
PubMed ID: 11918218
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6686
Naraba H, Yokoyama C, Tago N, Murakami M, Kudo I, Fueki M, Oh-Ishi S, Tanabe T.
Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1.
J Biol Chem
2002
277(32):28601-8
PubMed ID: 12034740
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15299
Shibuya A, Wada K, Nakajima A, Saeki M, Katayama K, Mayumi T, Kadowaki T, Niwa H, Kamisaki Y.
Nitration of PPARgamma inhibits ligand-dependent translocation into the nucleus in a macrophage-like cell line, RAW 264
FEBS Lett
2002
525(1-3):43-7
PubMed ID: 12163159
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15390
Tsuboi N, Yoshikai Y, Matsuo S, Kikuchi T, Iwami K, Nagai Y, Takeuchi O, Akira S, Matsuguchi T.
Roles of toll-like receptors in C-C chemokine production by renal tubular epithelial cells
J Immunol
2002
169(4):2026-33
PubMed ID: 12165529
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15391
Shuji Kojima, Risa Kurozumi, Maiko Tuchiya
A New Functional Role of 5,6,7,8-tetrahydrobiopterin (BH4) as an Inhibitor of γ-glutamylcysteine Synthetase (γ-GCS) mRNA Expression
pteridines
2002
13:83-88
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15392
Risa Kurozumi, Shuji Kojima
Low-level Nitric Oxide Blunts Oxidant Injury via Up-regulating Glutathione Synthes.
Journal of Health Science
2002
48:140-147
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2504
Haruta I, Kato Y, Hashimoto E, Minjares C, Kennedy S, Uto H, Yamauchi K, Kobayashi M, Yusa S, Muller U, Hayashi N, Miyazaki T
Association of AIM, a novel apoptosis inhibitory factor, with hepatitis via supporting macrophage survival and enhancing phagocytotic function of macrophages.
J Biol Chem
2001
276:22910-4
PubMed ID: 11294859
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2973
Shiina T, Morimatsu M, Kitamura H, Ito T, Kidou S, Matsubara K, Matsuda Y, Saito M, Syuto B
Genomic organization, chromosomal localization, and promoter analysis of the mouse Mail gene.
Immunogenetics
2001
53:649-55
PubMed ID: 11797098
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3777
Arima H, Kihara F, Hirayama F, Uekama K.
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A novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines
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Makoto Ayaori, Emi Yakushiji, Masatsune Ogura, Kazuhiro Nakaya, Tetsuya Hisada, Harumi Uto-Kondo, Shunichi Takiguchi, Yoshio Terao, Makoto Sasaki, Tomohiro Komatsu, Maki Iizuka, Makiko Yogo, Yoshinari Uehara, Hiroyuki Kagechika, Tsuyoshi Nakanishi, Katsunori Ikewaki
Retinoic acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages
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Involvement of Salmonella enterica serovar Typhi RpoS in resistance to NO-mediated host defense against serovar Typhi infection
Microb Pathog
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