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Cell No. : Cell Name
RCB0535 : RAW 264  update : 2024/05/14
CommentMouse leukemic monocyte. Abelson leukemia virus induced. Since “Terms and conditions” etc. for this cell line can be changed, the users of this cell line must refer to ECACC 85062803 prior to order. Application consideration(PDF 580KB)
Comment from the depositor
Terms and conditions1) There is no restriction regarding use for basic researches. However, since “Terms and conditions” etc. for this cell line can be changed, the users of this cell line must refer to ECA85062803 prior to order. 2) In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor ECACC
Year of deposit 1990
Animal _mouse < Mammals
Strain name BALB/c
Tissue leukemic monocyte
Classification transformed
History overseas, ECACC
Lifespan infinite
Morphology other
Cellosaurus(Expasy) CVCL_4478
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Culture medium MEM + 10% FBS + 0.1mM NEAA
Antibiotics Free
Passage method 0.25% Trypsin + (0.02% EDTA or 0.04% EDTA)
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
SSLP(mouse) OK
deposit info
lot info
Reference information Reference 3
User's Publication 744

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262  Ralph P, Ito M, Broxmeyer HE, Nakoinz I.  Corticosteroids block newly induced but not constitutive functions of macrophage cell lines: myeloid colony-stimulating activity production, latex phagocytosis, and antibody-dependent lysis of RBC and tumor targets  J Immunol  1978  121(1):300-3  PubMed ID: 670703  
34  Raschke WC, Baird S, Ralph P, Nakoinz I.  Functional macrophage cell lines transformed by Abelson leukemia virus  Cell  1978  15(1):261-7  PubMed ID: 212198   DOI: 10.1016/0092-8674(78)90101-0
716  Ralph P, Nakoinz I  Antibody-dependent killing of erythrocyte and tumor targets by macrophage-related cell lines: enhancement by PPD and LPS.  J Immunol  1977  119:950-54  PubMed ID: 894031  

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User's Publication
19707  Mingyue Gao, Tatsuaki Tagami, Koki Ogawa, Tetsuya Ozeki  Preparation and in vitro characterization of clofazimine-loaded albumin nanocomposite microparticles for inhalation therapy  Journal of Drug Delivery Science and Technology  2024  93:105364    DOI: 10.1016/j.jddst.2024.105364
19769  Matsui R, Endo K, Saiki T, Haga H, Shen W, Wang X, Yamazaki S, Katayama S, Nagata K, Kitamura H, Tanaka S.  Characterization and anti-tumor activities of polysaccharide isolated from Brassica rapa L. via activation of macrophages through TLR2-and TLR4-Dependent pathways  Arch Biochem Biophys  2024  752:109879  PubMed ID: 38160699   DOI: 10.1016/
19879  Sarangowa Ochir, Anuu Zorig, Qiherima Wang, Mikako Takasugi, Takashi Yamagishi, Hirofumi Arai  Isolation of two flavonol glycosides from Rosa rugosa pollen and their anti-inflammatory effect in lipopolysaccharide-stimulated macrophages  Food Science and Technology Research  2024      DOI: 10.3136/fstr.fstr-d-23-00178
19916  Takeuchi T, Oyama M, Tamura M, Arata Y, Hatanaka T.  Reduced form of Galectin-1 Suppresses Osteoclastic Differentiation of Human Peripheral Blood Mononuclear Cells and Murine RAW264 Cells In Vitro  Biomolecules  2024  14(1):121  PubMed ID: 38254721   DOI: 10.3390/biom14010121
21550  Sasaki Y, Nakatsuka R, Inoue A, Inouchi T, Masutani M, Nozaki T.  Dysfunction of poly (ADP-ribose) glycohydrolase suppresses osteoclast differentiation in RANKL-stimulated RAW264 cells.  Biochem Biophys Res Commun  2024  692:149309  PubMed ID: 38048727   DOI: 10.1016/j.bbrc.2023.149309
21556  Takeda T, Azumi J, Masaki M, Nagasawa T, Shimada Y, Aso H, Nakamura T.  Organogermanium, Ge-132, promotes the clearance of senescent red blood cells via macrophage-mediated phagocyte activation.  Heliyon  2024  10(1):e23296  PubMed ID: 38163191   DOI: 10.1016/j.heliyon.2023.e23296
21560  Wang A, Uchida K, Yokoyama A, Higashino F, Yasuda M.  Human adenovirus oncolytic properties and the inhibitory role of E4 orf4 and E4 orf6/7 on endogenously activated NF-κB.  Biochem Biophys Rep  2024  37:101616  PubMed ID: 38205184   DOI: 10.1016/j.bbrep.2023.101616
21574  Kawakami K, Fukuda T, Toyoda M, Nakao Y, Hayashi C, Watanabe Y, Aoki T, Shinjo T, Iwashita M, Yamashita A, Shida M, Sanui T, Uchiumi T, Nishimura F.  Luteolin Is a Potential Immunomodulating Natural Compound against Pulpal Inflammation.  Biomed Res Int  2024  2024:8864513  PubMed ID: 38304347   DOI: 10.1155/2024/8864513
21604  Nishimori M, Hayasaka N, Otsui K, Inoue N, Asakura J, Nagao M, Toh R, Ishida T, Hirata KI, Furuyashiki T, Shinohara M.  Stress-induced stenotic vascular remodeling via reduction of plasma omega-3 fatty acid metabolite 4-oxoDHA by noradrenaline.  Sci Rep  2024  14(1):4178  PubMed ID: 38378892   DOI: 10.1038/s41598-024-54867-3
21675  Takeuchi T, Oyama M, Hatanaka T.  Effect of Chitosan Degradation Products, Glucosamine and Chitosan Oligosaccharide, on Osteoclastic Differentiation.  BioTech (Basel)  2024  13(1)  PubMed ID: 38534915   DOI: 10.3390/biotech13010006
21693  Chen C, Xia G, Zhang S, Tian Y, Wang Y, Zhao D, Xu H.  Omics-based approaches for discovering active ingredients and regulating gut microbiota of Actinidia arguta exosome-like nanoparticles.  Food Funct  2024    PubMed ID: 38632897   DOI: 10.1039/d3fo05783f
21703  Hobro AJ, Pavillon N, Koike K, Sugiyama T, Umakoshi T, Verma P, Fujita K, Smith NI.  Imaging vs Nonimaging Raman Spectroscopy for High-Throughput Single-Cell Phenotyping.  Anal Chem  2024    PubMed ID: 38653469   DOI: 10.1021/acs.analchem.4c00236
21711  Yusuke Hanaki, Rintaro Abe, Yasunori Sugiyama, Yasumasa Hara, Ryo C. Yanagita  A new labdane-type diterpenoid from leaves of Vitex rotundifolia  Results in Chemistry  2024  7:101512    DOI: 10.1016/j.rechem.2024.101512
17750  Kitazawa S, Haraguchi R, Takaoka Y, Kitazawa R.  In situ sequence-specific visualization of single methylated cytosine on tissue sections using ICON probe and rolling-circle amplification  Histochem Cell Biol  2023  159(3):263-273  PubMed ID: 36418613   DOI: 10.1007/s00418-022-02165-2
17768  Azumi J, Takeda T, Shimada Y, Zhuang T, Tokuji Y, Sakamoto N, Aso H, Nakamura T.  Organogermanium THGP Induces Differentiation into M1 Macrophages and Suppresses the Proliferation of Melanoma Cells via Phagocytosis  Int J Mol Sci  2023  24(3):1885  PubMed ID: 36768216   DOI: 10.3390/ijms24031885
17770  Yao D, Guo J, Qin T, Chen H, Jin S.  Effect of Alleviating Fibrosis with EGCG-Modified Bone Graft in Murine Model Depended on Less Accumulation of Inflammatory Macrophage  Biomed Res Int  2023  2023:9466110  PubMed ID: 36820222   DOI: 10.1155/2023/9466110
17779  Sansawat, A., Ratanacoon, M. and Nitteranon, V.  Antioxidative, anti-inflammatory, antibacterial, and anti- adhesive activities of different solvent extracts from various parts of Basella rubra L.  International Journal of Agricultural Technology  2023  19(2):655-668   
19556  Terasawa M, Zang L, Hiramoto K, Shimada Y, Mitsunaka M, Uchida R, Nishiura K, Matsuda K, Nishimura N, Suzuki K.  Oral Administration of Rhamnan Sulfate from Monostroma nitidum Suppresses Atherosclerosis in ApoE-Deficient Mice Fed a High-Fat Diet  Cells  2023  12(22):2666.  PubMed ID: 37998401   DOI: 10.3390/cells12222666
19608  Fujimoto D, Shinohara M, Kawamori H, Toba T, Kakizaki S, Nakamura K, Sasaki S, Hamana T, Fujii H, Osumi Y, Hayasaka N, Kishino S, Ogawa J, Hirata KI, Otake H.  The relationship between unique gut microbiome-derived lipid metabolites and subsequent revascularization in patients who underwent percutaneous coronary intervention  Atherosclerosis  2023  375:1-8  PubMed ID: 37216727   DOI: 10.1016/j.atherosclerosis.2023.05.001
19718  He C, Miyazawa T, Abe C, Ueno T, Suzuki M, Mizukami M, Kurihara K, Toda M.  Hypolipidemic and Anti-Inflammatory Effects of Curcuma longa-Derived Bisacurone in High-Fat Diet-Fed Mice  Int J Mol Sci  2023  24(11):9366  PubMed ID: 37298318   DOI: 10.3390/ijms24119366
19745  Alvarenga L, Saldanha JF, Stockler-Pinto MB, Fouque D, Soulage CO, Mafra D.  Effects of resveratrol on inflammation and oxidative stress induced by the uremic toxin indoxyl sulfate in Murine macrophage-like RAW 264.7  Biochimie  2023  213:22-29.  PubMed ID: 37142118   DOI: 10.1016/j.biochi.2023.05.001
19767  Tomohiro Itoh, Mai Muramatsu, Daiki Miyazono, Mamoru Koketsu, Shingo Fujita, Toshiharu Hashizume  Phenolic Glycosides Citrulluside H and Citrulluside T Isolated From Young Watermelon (Citrullus lanatus) Fruit Have Beneficial Effects Against Cutibacterium acnes-Induced Skin Inflammation  Natural Product Communications  2023  18:1934578X2211432    DOI: 10.1177/1934578x221143202
19824  Seta Y, Kawakatsu K, Degawa S, Goto T, Nishikata T.  Morphological Evidence for Novel Roles of Microtubules in Macrophage Phagocytosis  Int J Mol Sci  2023  24(2):1373  PubMed ID: 36674886   DOI: 10.3390/ijms24021373
19834  Shimazu T, Yoshimoto R, Kotoshiba K, Suzuki T, Matoba S, Hirose M, Akakabe M, Sohtome Y, Sodeoka M, Ogura A, Dohmae N, Shinkai Y.  Histidine N1-position-specific methyltransferase CARNMT1 targets C3H zinc finger proteins and modulates RNA metabolism  Genes Dev  2023  37(15-16):724-742  PubMed ID: 37612136   DOI: 10.1101/gad.350755.123
19850  Muramatsu D, Uchiyama H, Higashi H, Kida H, Iwai A.  Effects of heat degradation of betanin in red beetroot (Beta vulgaris L.) on biological activity and antioxidant capacity  PLoS One  2023  18(5):e0286255  PubMed ID: 37228098   DOI: 10.1371/journal.pone.0286255
19865  Munekane M, Mori H, Takada N, Sano K, Yamasaki T, Tanaka T, Sasaki N, Rikitake Y, Mukai T.  Preparation and evaluation of 111In-labeled liposomes containing phosphatidylglycerol for detection of macrophages in atherosclerotic plaques  Nucl Med Biol  2023  126-127:108388  PubMed ID: 37804560   DOI: 10.1016/j.nucmedbio.2023.108388
19896  Boxue Yang, Wenzhao Li, Asuka Ishii, Ga-hyun Joe, Yutaka Shimizu, Yasuaki Takagi, Hiroki Saeki  Advanced Utilization of By-Product from the Sturgeon Aquaculture Industry: Optimum Preparation of Notochord-Derived Multifunctional Peptides by Glycation using the Maillard Reaction  Waste and Biomass Valorization  2023  14:4101-4111    DOI: 10.1007/s12649-023-02113-8
19915  Xiao L, Shiwaku Y, Hamai R, Baba K, Tsuchiya K, Imazato S, Sasaki K, Suzuki O.  Osteogenic capacity of octacalcium phosphate involving macrophage polarization  J Biomed Mater Res A  2023  111(7):1006-1020  PubMed ID: 36573692   DOI: 10.1002/jbm.a.37484
19981  Segawa R, Kyoda T, Yagisawa M, Muramatsu T, Hiratsuka M, Hirasawa N.  Hypoxia-inducible factor prolyl hydroxylase inhibitors suppressed thymic stromal lymphopoietin production and allergic responses in a mouse air-pouch-type ovalbumin sensitization model  Int Immunopharmacol  2023  118:110127  PubMed ID: 37030118   DOI: 10.1016/j.intimp.2023.110127
19997  Tiskratok W, Yamada M, Watanabe J, Pengyu Q, Kimura T, Egusa H.  Mechanoregulation of Osteoclastogenesis-Inducing Potentials of Fibrosarcoma Cell Line by Substrate Stiffness  Int J Mol Sci  2023  24(10):8959  PubMed ID: 37240303   DOI: 10.3390/ijms24108959
21032  Do KM, Kodama T, Nguyen HM, Ikumi N, Soeda C, Shiokawa KI, Morita H.  Seco- and isopimarane diterpenoids from Kaempferia marginata rhizomes and their NO inhibition activities.  Phytochemistry  2023  205:113510  PubMed ID: 36379318   DOI: 10.1016/j.phytochem.2022.113510
21098  Tanikawa T, Kitamura M, Hayashi Y, Tomida N, Uwaya A, Isami F, Yokogawa T, Inoue Y.  Anti-inflammatory Effect of a Combination of Cannabidiol and Morinda citrifolia Extract on Lipopolysaccharide-stimulated RAW264 Macrophages.  In Vivo  2023  37(2):591-595  PubMed ID: 36881078   DOI: 10.21873/invivo.13117
21126  Ueda K, Ma C, Izumiya M, Kuroda C, Ishida H, Uemura T, Saito N, Aoki K, Haniu H.  Biocompatibility Evaluation of Carbon Nanohorns in Bone Tissues.  Nanomaterials (Basel)  2023  13(2)  PubMed ID: 36677997   DOI: 10.3390/nano13020244
21152  Fukuta T, Ikeda-Imafuku M, Kodama S, Kuse J, Matsui K, Iwao Y.  One-Step Pharmaceutical Preparation of PEG-Modified Exosomes Encapsulating Anti-Cancer Drugs by a High-Pressure Homogenization Technique.  Pharmaceuticals (Basel)  2023  16(1)  PubMed ID: 36678605   DOI: 10.3390/ph16010108
21155  Arimura N, Watanabe H, Kato H, Imafuku T, Nakano T, Sueyoshi M, Chikamatsu M, Tokumaru K, Nagasaki T, Maeda H, Tanaka M, Matsushita K, Maruyama T.  Advanced Oxidation Protein Products Contribute to Chronic-Kidney-Disease-Induced Adipose Inflammation through Macrophage Activation.  Toxins (Basel)  2023  15(3)  PubMed ID: 36977070   DOI: 10.3390/toxins15030179
21161  Amang À Ngnoung GA, Sidjui LS, Leutcha PB, Nganso Ditchou YO, Tchokouaha LRY, Herbette G, Baghdikian B, Kowa TK, Soh D, Kemzeu R, Poka M, Demana PH, Siwe Noundou X, Tchinda AT, Fekam Boyom F, Lannang AM, Nyassé B.  Antileishmanial and Antiplasmodial Activities of Secondary Metabolites from the Root of Antrocaryon klaineanum Pierre (Anacardiaceae).  Molecules  2023  28(6)  PubMed ID: 36985700   DOI: 10.3390/molecules28062730
21180  Uchiyama H, Muramatsu D, Higashi H, Kida H, Iwai A.  Effects of chondroitin sulfate oligosaccharides on osteoclast differentiation of RAW264 cells, and myotube differentiation of C2C12 cells.  PLoS One  2023  18(4):e0284343  PubMed ID: 37053208   DOI: 10.1371/journal.pone.0284343
21191  Hirano-Kusuda M, Setoguchi S, Koga M, Goto S, Yamada A, Watase D, Nagata-Akaho N, Karube Y, Matsunaga K, Takata J.  Cationic Ester Prodrugs of Curcumin with N,N-dimethyl Amino Acid Promoieties Improved Poor Water Solubility and Intestinal Absorption.  Pharm Res  2023    PubMed ID: 37081301   DOI: 10.1007/s11095-023-03500-5
21207  Takahashi S, Ferdousi F, Yamamoto S, Hirano A, Nukaga S, Nozaki H, Isoda H.  Botryococcus terribilis Ethanol Extract Exerts Anti-inflammatory Effects on Murine RAW264 Cells.  Int J Mol Sci  2023  24(7)  PubMed ID: 37047640   DOI: 10.3390/ijms24076666
21213  Murata T, Jamsransuren D, Matsuda S, Ogawa H, Takeda Y.  Rapid Virucidal Activity of Japanese Saxifraga Species-Derived Condensed Tannins against SARS-CoV-2, Influenza A Virus, and Human Norovirus Surrogate Viruses.  Appl Environ Microbiol  2023  e0023723  PubMed ID: 37184410   DOI: 10.1128/aem.00237-23
21244  Kato M, Yamaguchi M, Ooka A, Takahashi R, Suzuki T, Onoda K, Yoshikawa Y, Tsunematsu Y, Sato M, Yoshioka Y, Igarashi M, Hayakawa S, Shoji K, Shoji Y, Ishikawa T, Watanabe K, Miyoshi N.  Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice.  Sci Rep  2023  13(1):8924  PubMed ID: 37264108   DOI: 10.1038/s41598-023-36091-7
21268  Nakamura Y, Matsumoto H, Wu CH, Fukaya D, Uni R, Hirakawa Y, Katagiri M, Yamada S, Ko T, Nomura S, Wada Y, Komuro I, Nangaku M, Inagi R, Inoue T.  Alpha 7 nicotinic acetylcholine receptors signaling boosts cell-cell interactions in macrophages effecting anti-inflammatory and organ protection.  Commun Biol  2023  6(1):666  PubMed ID: 37353597   DOI: 10.1038/s42003-023-05051-2
21282  Ishizaka T, Horiuchi K, Kondo S, Isaji M, Nakagawa T, Inoue M, Rikitake H, Taguchi E, Susa M, Yoda M, Ono T, Kozai Y, Chiba K.  Eribulin mesylate induces bone mass loss by promoting osteoclastic bone resorption in mice.  Bone Rep  2023  18:101693  PubMed ID: 37305428   DOI: 10.1016/j.bonr.2023.101693
21306  Kotaro Sakamoto, Wararat Kittikulsuth, Eijiro Miyako, Akumwami Steeve, Rika Ishimura, Shinsaku Nakagawa, Yukio Ago, Akira Nishiyama  The VIPR2-selective antagonist KS-133 changes macrophage polarization and exerts potent anti-tumor effects as a single agent and in combination with an anti-PD-1 antibody  PLoS ONE  2023  5;18(7):e0286651  PubMed ID: 37405999   DOI: 10.1371/journal.pone.0286651
21351  Yasuda K, Maeda H, Kinoshita R, Minayoshi Y, Mizuta Y, Nakamura Y, Imoto S, Nishi K, Yamasaki K, Sakuragi M, Nakamura T, Ikeda-Imafuku M, Iwao Y, Ishima Y, Ishida T, Iwakiri Y, Otagiri M, Watanabe H, Maruyama T.  Encapsulation of an Antioxidant in Redox-Sensitive Self-Assembled Albumin Nanoparticles for the Treatment of Hepatitis.  ACS Nano  2023    PubMed ID: 37579503   DOI: 10.1021/acsnano.3c02877
21365  Togami K, Zhan X, Ishizawa K, Miyakoshi K, Miyao A, Quan P, Chono S.  Development of LOX-1 Antibody Modified Immuno-liposomes as Drug Carriers to Macrophages in Atherosclerotic Lesions.  Pharmazie  2023  78(8):113-116  PubMed ID: 37592420   DOI: 10.1691/ph.2023.3004
21487  Tsuchiya A, Suzuki M, Ryotaro I, Batubara I, Yamauchi K, Mitsunaga T.  New flavan trimer from Daemonorops draco as osteoclastogenesis inhibitor.  Fitoterapia  2023  105757  PubMed ID: 38008129   DOI: 10.1016/j.fitote.2023.105757
21512  Saito S, Banno T, Arai MA.  3-Hydroxy-3-(2-oxopropyl)indolin-2-one, a product of a human-derived Enterocloster strain, is an inhibitor of nitric oxide production.  Biosci Biotechnol Biochem  2023    PubMed ID: 38086614   DOI: 10.1093/bbb/zbad172
21517  Toita R, Kitamura M, Tsuchiya A, Kang JH, Kasahara S.  Releasable, Immune-Instructive, Bioinspired Multilayer Coating Resists Implant-Induced Fibrosis while Accelerating Tissue Repair.  Adv Healthc Mater  2023  e2302611  PubMed ID: 38095751   DOI: 10.1002/adhm.202302611
21530  Watanabe N, Tamai R, Kiyoura Y.  Alendronate augments lipid A‑induced IL‑1β release by ASC‑deficient RAW264 cells via AP‑1 activation.  Exp Ther Med  2023  26(6):577  PubMed ID: 38023354   DOI: 10.3892/etm.2023.12276
17548  Synthesis of a Dual-Color Fluorescent Dendrimer for Diagnosis of Cancer Metastasis in Lymph Nodes.  Synthesis of a Dual-Color Fluorescent Dendrimer for Diagnosis of Cancer Metastasis in Lymph Nodes  Polymers (Basel)  2022  14(20):4314  PubMed ID: 36297891   DOI: 10.3390/polym14204314
17561  Shan Q, Takabatake K, Kawai H, Oo MW, Sukegawa S, Fujii M, Nakano K, Nagatsuka H.  Crosstalk between cancer and different cancer stroma subtypes promotes the infiltration of tumor‑associated macrophages into the tumor microenvironment of oral squamous cell carcinoma  Int J Oncol  2022  60(6):78  PubMed ID: 35514301   DOI: 10.3892/ijo.2022.5368
17568  Wang D, Nagata M, Matsumoto M, Amen Y, Wang D, Shimizu K.  Potential of Hibiscus sabdariffa L. and Hibiscus Acid to Reverse Skin Aging  Molecules  2022  27(18):6076  PubMed ID: 36144809   DOI: 10.3390/molecules27186076
17593  Mamta Kumawat, Harishkumar Madhyastha, Mandeep Singh, Devendra Jain, Hemant Kumar Daima  Functional silver nanozymes regulate cell inflammatory cytokines expression in mouse macrophages  Colloids and Surfaces A: Physicochemical and Engineering Aspects  2022  650:129294    DOI: 10.1016/j.colsurfa.2022.129294
17603  Saiki P, Yoshihara M, Kawano Y, Miyazaki H, Miyazaki K.  Anti-Inflammatory Effects of Heliangin from Jerusalem Artichoke ( Helianthus tuberosus) Leaves Might Prevent Atherosclerosis  Biomolecules  2022  12(1):91  PubMed ID: 35053238   DOI: 10.3390/biom12010091
17621  Nagase K, Kojima N, Goto M, Akaike T, Kanazawa H.  Thermoresponsive block copolymer brush for temperature-modulated hepatocyte separation  J Mater Chem B  2022  10(42):8629-8641  PubMed ID: 35972447   DOI: 10.1039/d2tb01384c
17641  Suzuki Y, Kikuchi T, Goto H, Takayanagi Y, Kawamura S, Sawada N, Naiki Y, Kondo H, Hayashi JI, Hasegawa Y, Mitani A.  Porphyromonas gingivalis Fimbriae Induce Osteoclastogenesis via Toll-like Receptors in RAW264 Cells  Int J Mol Sci  2022  23(23):15293  PubMed ID: 36499621   DOI: 10.3390/ijms232315293
17685  Fang K, Murakami Y, Kanda S, Shimono T, Dang AT, Ono M, Nishiyama T.  Unkeito Suppresses RANKL-Mediated Osteoclastogenesis via the Blimp1-Bcl6 and NF-κB Signaling Pathways and Enhancing Osteoclast Apoptosis  Int J Mol Sci  2022  23(14):7814  PubMed ID: 35887169   DOI: 10.3390/ijms23147814
17693  Agista AZ, Tanuseputero SA, Koseki T, Ardiansyah, Budijanto S, Sultana H, Ohsaki Y, Yeh CL, Yang SC, Komai M, Shirakawa H.  Tryptamine, a Microbial Metabolite in Fermented Rice Bran Suppressed Lipopolysaccharide-Induced Inflammation in a Murine Macrophage Model  Int J Mol Sci  2022  23(19):11209  PubMed ID: 36232510   DOI: 10.3390/ijms231911209
17749  Saito M, Watanabe H, Sasaki M, Ookubo M, Yarita T, Shiraiwa M, Asayama M.  Coproduction of lipids and carotenoids by the novel green alga Coelastrella sp. depending on cultivation conditions  Biotechnol Rep (Amst)  2022  e00769  PubMed ID: 36660172   DOI: 10.1016/j.btre.2022.e00769
18219  Shiba H, Nishio M, Sawada M, Tamaki M, Michigami M, Nakai S, Nakase I, Fujii I, Matsumoto A, Kojima C.  Carboxy-terminal dendrimers with phenylalanine for a pH-sensitive delivery system into immune cells including T cells  J Mater Chem B  2022  10(14):2463-2470  PubMed ID: 34935852   DOI: 10.1039/d1tb01980e
20345  Thein HSS, Hashimoto K, Kawashima N, Noda S, Okiji T.  Evaluation of the anti-inflammatory effects of surface-reaction-type pre-reacted glass-ionomer filler containing root canal sealer in lipopolysaccharide-stimulated RAW264.7 macrophages.  Dent Mater J  2022    PubMed ID: 34602587   DOI: 10.4012/dmj.2021-139
20526  Aki T, Funakoshi T, Unuma K, Uemura K.  Inverse regulation of GSDMD and GSDME gene expression during LPS-induced pyroptosis in RAW264.7 macrophage cells.  Apoptosis  2022    PubMed ID: 35006493   DOI: 10.1007/s10495-022-01708-1
20542  Do KM, Kodama T, Shin MK, Nu LHT, Nguyen HM, Dang SV, Shiokawa KI, Hayakawa Y, Morita H.  Marginols A‒H, unprecedented pimarane diterpenoids from Kaempferia marginata and their NO inhibitory activities.  Phytochemistry  2022  196:113109  PubMed ID: 35091214   DOI: 10.1016/j.phytochem.2022.113109
16213  Jing‐Yi Xue, Giedre Grigelioniene, Zheng Wang, Gen Nishimura, Aritoshi Iida, Naomichi Matsumoto, Emma Tham, Noriko Miyake, Shiro Ikegawa, Long Guo  SLC4A2 Deficiency Causes a New Type of Osteopetrosis  J Bone Miner Res  2022  37(2):226-235  PubMed ID: 34668226   DOI: 10.1002/jbmr.4462
20578  Akashi Y, Nagasaki A, Okawa H, Matsumoto T, Kondo T, Yatani H, Nishimura I, Egusa H.  Cyclic Pressure-Induced Cytokines from Gingival Fibroblasts Stimulate Osteoclast Activity: Clinical Implications for Alveolar Bone Loss in Denture Wearers.  J Prosthodont Res  2022    PubMed ID: 35185110   DOI: 10.2186/jpr.JPR_D_21_00238
16345  Kumawat M, Madhyastha H, Umapathi A, Singh M, Revaprasadu N, Daima HK.  Surface Engineered Peroxidase-Mimicking Gold Nanoparticles to Subside Cell Inflammation  Langmuir  2022  38(5):1877-1887  PubMed ID: 35099982   DOI: 10.1021/acs.langmuir.1c03088
16431  Do KM, Shin MK, Kodama T, Win NN, Prema P, Nguyen HM, Hayakawa Y, Morita H.  Flavanols and Flavanes from Crinum asiaticum and Their Effects on LPS Signaling Pathway Through the Inhibition of NF-κB Activation  Planta Med  2022  88(11):913-920  PubMed ID: 34474490   DOI: 10.1055/a-1585-5877
20620  Kieu TQ, Tazawa K, Kawashima N, Noda S, Fujii M, Nara K, Hashimoto K, Han P, Okiji T.  Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitro.  Sci Rep  2022  12(1):5176  PubMed ID: 35338195   DOI: 10.1038/s41598-022-08987-3
20635  Shinomiya K, Mukai A, Ito E, Yoneda K, Ueno M, Sotozono C, Kinoshita S, Hamuro J.  Potential participation of CTRP6, a complement regulator, in the pathology of age related macular degeneration.  Jpn J Ophthalmol  2022    PubMed ID: 35397057   DOI: 10.1007/s10384-022-00913-4
20655  Temizoz B, Hioki K, Kobari S, Jounai N, Kusakabe T, Lee MSJ, Coban C, Kuroda E, Ishii KJ.  Anti-tumor immunity by transcriptional synergy between TLR9 and STING activation.  Int Immunol  2022    PubMed ID: 35419609   DOI: 10.1093/intimm/dxac012
20689  Li W, Miyashita A, Sekimizu K.  Peanut triacylglycerols activate innate immunity both in insects and mammals.  Sci Rep  2022  12(1):7464  PubMed ID: 35523841   DOI: 10.1038/s41598-022-11494-0
16504  Zhou Y, Takano T, Li X, Wang Y, Wang R, Zhu Z, Tanokura M, Miyakawa T, Hachimura S.  β-elemene regulates M1-M2 macrophage balance through the ERK/JNK/P38 MAPK signaling pathway  Commun Biol  2022  5(1):519  PubMed ID: 35641589   DOI: 10.1038/s42003-022-03369-x
16619  Mohamed IMA, Jamsransuren D, Matsuda S, Ogawa H, Takeda Y.  Impact of Theaflavins-Enriched Tea Leaf Extract TY-1 against Surrogate Viruses of Human Norovirus: In Vitro Virucidal Study  Pathogens  2022  11(5):533  PubMed ID: 35631054   DOI: 10.3390/pathogens11050533
16642  Gulay KCM, Aoshima K, Maekawa N, Suzuki T, Konnai S, Kobayashi A, Kimura T.  Hemangiosarcoma cells induce M2 polarization and PD-L1 expression in macrophages  Sci Rep  2022  12(1):2124  PubMed ID: 35136176   DOI: 10.1038/s41598-022-06203-w
16558  Ito S, Nishiguchi A, Ichimaru H, Nagasaka K, Hirade H, Taguchi T.  Prevention of postoperative adhesion with a colloidal gel based on decyl group-modified Alaska pollock gelatin microparticles  Acta Biomater  2022  S1742-7061(22)00354-3  PubMed ID: 35697199   DOI: 10.1016/j.actbio.2022.06.014
16540  Elia Marin, Tetsuya Adachi, Francesco Boschetto, Wenliang Zhu, Keiji Adachi, Narisato Kanamura, Toshiro Yamamoto, Giuseppe Pezzotti  Raman Spectroscopic Investigation of Osteoclastic Activity under the Influence of Bisphosphonate  Applied Sciences  2022  12:3757    DOI: 10.3390/app12083757
16385  Shan Q, Takabatake K, Kawai H, Oo MW, Inada Y, Sukegawa S, Fushimi S, Nakano K, Nagatsuka H.  Significance of cancer stroma for bone destruction in oral squamous cell carcinoma using different cancer stroma subtypes  Oncol Rep  2022  47(4):81  PubMed ID: 35211756   DOI: 10.3892/or.2022.8292
20820  Kurata A, Kiyohara S, Imai T, Yamasaki-Yashiki S, Zaima N, Moriyama T, Kishimoto N, Uegaki K.  Characterization of extracellular vesicles from Lactiplantibacillus plantarum.  Sci Rep  2022  12(1):13330  PubMed ID: 35941134   DOI: 10.1038/s41598-022-17629-7
20823  Shi Y, Yasui M, Hara-Chikuma M.  AQP9 transports lactate in tumor-associated macrophages to stimulate an M2-like polarization that promotes colon cancer progression.  Biochem Biophys Rep  2022  31:101317  PubMed ID: 35967760   DOI: 10.1016/j.bbrep.2022.101317
17097  Kartikasari N, Yamada M, Watanabe J, Tiskratok W, He X, Kamano Y, Egusa H.  Titanium surface with nanospikes tunes macrophage polarization to produce inhibitory factors for osteoclastogenesis through nanotopographic cues  Acta Biomater  2022  137:316-330  PubMed ID: 34673230   DOI: 10.1016/j.actbio.2021.10.019
20837  Ueno S, Sudo T, Saya H, Sugihara E.  Pigment epithelium-derived factor promotes peritoneal dissemination of ovarian cancer through induction of immunosuppressive macrophages.  Commun Biol  2022  5(1):904  PubMed ID: 36056141   DOI: 10.1038/s42003-022-03837-4
20863  Tanaka KI, Nakaguchi S, Shiota S, Nakada Y, Oyama K, Sakakibara O, Shimoda M, Sugimoto A, Ichitani M, Takihara T, Kinugasa H, Kawahara M.  Preventive Effect of Epigallocatechin Gallate, the Main Component of Green Tea, on Acute Lung Injury Caused by Air Pollutants.  Biomolecules  2022  12(9)  PubMed ID: 36139034   DOI: 10.3390/biom12091196
20886  Shan Q, Takabatake K, Omori H, Kawai H, Oo MW, Sukegawa S, Fujii M, Inada Y, Sano S, Nakano K, Nagatsuka H.  Investigation of bone invasion and underlying mechanisms of oral cancer using a cell line-derived xenograft model.  Oncol Lett  2022  24(5):382  PubMed ID: 36238359   DOI: 10.3892/ol.2022.13502
20903  Kumawat M, Madhyastha H, Singh M, Revaprasadu N, Srinivas SP, Daima HK.  Double functionalized haemocompatible silver nanoparticles control cell inflammatory homeostasis.  PLoS One  2022  17(10):e0276296  PubMed ID: 36269783   DOI: 10.1371/journal.pone.0276296
17314  Ota N, Tanaka N, Sato A, Shen Y, Yalikun Y, Tanaka Y.  Microenvironmental Analysis and Control for Local Cells under Confluent Conditions via a Capillary-Based Microfluidic Device  Anal Chem  2022  Nov 16  PubMed ID: 36383697   DOI: 10.1021/acs.analchem.2c02815
17328  Azumi J, Shimada Y, Takeda T, Aso H, Nakamura T.  The Organogermanium Compound 3-(Trihydroxygermyl) Propanoic Acid (THGP) Suppresses Inflammasome Activation Via Complexation with ATP  J Biol Chem  2022  298(12):102676  PubMed ID: 36362152   DOI: 10.3390/ijms232113364
20959  Akita Y, Higashiyama M, Kurihara C, Ito S, Nishii S, Mizoguchi A, Inaba K, Tanemoto R, Sugihara N, Hanawa Y, Wada A, Horiuchi K, Okada Y, Narimatsu K, Komoto S, Tomita K, Takei F, Satoh Y, Saruta M, Hokari R.  Ameliorating Role of Hydrogen-Rich Water Against NSAID-Induced Enteropathy via Reduction of ROS and Production of Short-Chain Fatty Acids.  Dig Dis Sci  2022    PubMed ID: 36478314   DOI: 10.1007/s10620-022-07781-5
20962  Osonoi S, Mizukami H, Takeuchi Y, Sugawa H, Ogasawara S, Takaku S, Sasaki T, Kudoh K, Ito K, Sango K, Nagai R, Yamamoto Y, Daimon M, Yamamoto H, Yagihashi S.  RAGE activation in macrophages and development of experimental diabetic polyneuropathy.  JCI Insight  2022  7(23)  PubMed ID: 36477360   DOI: 10.1172/jci.insight.160555
20979  Motani K, Saito-Tarashima N, Nishino K, Yamauchi S, Minakawa N, Kosako H.  The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER.  Cell Rep  2022  41(12):111868  PubMed ID: 36543137   DOI: 10.1016/j.celrep.2022.111868
20989  Zhao D, Tu ATT, Shobo M, Le NBT, Yoshikawa C, Sugai K, Hakamata Y, Yamazaki T.  Non-Modified CpG Oligodeoxynucleotide Forming Guanine-Quadruplex Structure Complexes with ε-Poly-L-Lysine Induce Antibody Production as Vaccine Adjuvants.  Biomolecules  2022  12(12)  PubMed ID: 36551297   DOI: 10.3390/biom12121868
21025  Kojima S, Hakamata M, Asanuma T, Suzuki R, Tsuruda JI, Nonoyama T, Lin Y, Fukatsu H, Koide N, Umezawa K.  Cellular Anti-Inflammatory and Antioxidant Activities of Bamboo Sasa albomarginata Leaf Extract and Its Constituent Coumaric Acid Methyl Ester.  ScientificWorldJournal  2022  8454865  PubMed ID: 36330350   DOI: 10.1155/2022/8454865
17436  Watanabe M, Yahagi T, Shirayama T, Miyake K, Kotani H, Ogawa T, Matsuzaki K.  Effects of a Whole Plant Extract of Scutellaria rubropunctata var. rubropunctata on Bone Metabolism with Estrogen Receptor Activation  Plants (Basel)  2022  11(16):2075  PubMed ID: 36015379   DOI: 10.3390/plants11162075
11900  Fujihara Y, Abe T, Asawa Y, Nishizawa S, Saijo H, Hikita A, Hoshi K.  Influence of Damage-Associated Molecular Patterns from Chondrocytes in Tissue-Engineered Cartilage.  Tissue Eng Part A  2021  27(1-2):1-9  PubMed ID: 31724485   DOI: 10.1089/ten.TEA.2019.0185
13272  Tanaka KI, Kubota M, Shimoda M, Hayase T, Miyaguchi M, Kobayashi N, Ikeda M, Ishima Y, Kawahara M.  Thioredoxin-albumin fusion protein prevents urban aerosol-induced lung injury via suppressing oxidative stress-related neutrophil extracellular trap formation.  Environ Pollut  2021    PubMed ID: 33065363   DOI: 10.1016/j.envpol.2020.115787
13373  Kuriyama T, Fukuma Y, Imashiro C, Kabayama K, Kurashina Y, Takemura K.  Detachment of RAW264.7 macrophages from a culture dish using ultrasound excited by a Langevin transducer.  J Biosci Bioeng  2021  131(3):320-325  PubMed ID: 33250410   DOI: 10.1016/j.jbiosc.2020.11.003
13464  Sugiyama T, Hobro AJ, Pavillon N, Umakoshi T, Verma P, Smith N.  Label-free Raman mapping of saturated and unsaturated fatty acid uptake, storage, and return toward baseline levels in macrophages  Analyst  2021  146(4):1268-1280  PubMed ID: 33346264   DOI: 10.1039/d0an02077j
20004  Wada Y, Iyoda M, Matsumoto K, Suzuki T, Tachibana S, Kanazawa N, Honda H.  Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice.  PLoS One  2021  16(1):e0245340  PubMed ID: 33428678   DOI: 10.1371/journal.pone.0245340
20009  Li SW, Takahara T, Que W, Fujino M, Guo WZ, Hirano SI, Ye LP, Li XK.  Hydrogen-rich water protects liver injury in nonalcoholic steatohepatitis though HO-1 enhancement via IL-10 and Sirt 1 signaling.  Am J Physiol Gastrointest Liver Physiol  2021    PubMed ID: 33439102   DOI: 10.1152/ajpgi.00158.2020
20023  Madhyastha R, Madhyastha H, Nurrahmah QI, Purbasari B, Maruyama M, Nakajima Y.  MicroRNA 21 Elicits a Pro-inflammatory Response in Macrophages, with Exosomes Functioning as Delivery Vehicles.  Inflammation  2021    PubMed ID: 33501624   DOI: 10.1007/s10753-021-01415-0
20065  Ma'mag LK, Zintchem AAA, Théodora KK, de Théodore AA, Lauve TY, Frédérich M, Bikobo DSN, Pegnyemb DE.  Antiplasmodial and antileishmanial inhibitory activity of triterpenes and steroidal alkaloid from the leaves of Funtumia elastica (Preuss) Stapf (Apocynaceae).  Fitoterapia  2021  104869  PubMed ID: 33657429   DOI: 10.1016/j.fitote.2021.104869
20088  Nurrahmah QI, Madhyastha R, Madhyastha H, Purbasari B, Maruyama M, Nakajima Y.  Retinoic acid abrogates LPS-induced inflammatory response via negative regulation of NF-kappa B/miR-21 signaling.  Immunopharmacol Immunotoxicol  2021  1-10  PubMed ID: 33757404   DOI: 10.1080/08923973.2021.1902348
20176  Pengjam Y, Prajantasen T, Tonwong N, Panichayupakaranant P.  Downregulation of miR-21 gene expression by CRE-Ter to modulate osteoclastogenesis: De Novo mechanism.  Biochem Biophys Rep  2021  26:101002  PubMed ID: 33997317   DOI: 10.1016/j.bbrep.2021.101002
20196  Sano K, Miki M, Tanaka T, Munemura M, Munekane M, Yamasaki T, Mukai T.  Electrostatically self-assembled gold nanorods with chondroitin sulfate for targeted photothermal therapy for melanoma.  Photodiagnosis Photodyn Ther  2021  102402  PubMed ID: 34144259   DOI: 10.1016/j.pdpdt.2021.102402
20197  Ju N, Hayashi H, Shimamura M, Yoshida S, Nakamaru R, Nakagami H, Morishita R, Rakugi H.  Prevention of Acute Lung Injury by a Novel CD14-Inhibitory Receptor Activator of the NF-κB Ligand Peptide in Mice.  Immunohorizons  2021  5(6):438-447  PubMed ID: 34131020   DOI: 10.4049/immunohorizons.2000112
20199  Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.  Extracellular mRNA transported to the nucleus exerts translation-independent function.  Nat Commun  2021  12(1):3655  PubMed ID: 34135341   DOI: 10.1038/s41467-021-23969-1
20243  Hattori H, Takaoka K, Ueta M, Oshitani M, Tamaoka J, Noguchi K, Kishimoto H.  Senescent RAW264.7 cells exhibit increased production of nitric oxide and release inducible nitric oxide synthase in exosomes.  Mol Med Rep  2021  24(3)  PubMed ID: 34318909   DOI: 10.3892/mmr.2021.12320
20258  Yokota S, Matsumae G, Shimizu T, Hasegawa T, Ebata T, Takahashi D, Heguo C, Tian Y, Alhasan H, Takahata M, Kadoya K, Terkawi MA, Iwasaki N.  Cardiotrophin like cytokine factor 1 (CLCF1) alleviates bone loss in osteoporosis mouse models by suppressing osteoclast differentiation through activating interferon signaling and repressing the nuclear factor-κB signaling pathway.  Bone  2021  116140  PubMed ID: 34364014   DOI: 10.1016/j.bone.2021.116140
20264  Kawai K, Nishigaki A, Moriya S, Egami Y, Araki N.  Rab10-Positive Tubular Structures Represent a Novel Endocytic Pathway That Diverges From Canonical Macropinocytosis in RAW264 Macrophages.  Front Immunol  2021  12:649600  PubMed ID: 34135890   DOI: 10.3389/fimmu.2021.649600
20271  Takahashi F, Endo K, Matsui R, Yamamoto K, Tanaka S.  Brassica rapa L. activates macrophages via Toll-like receptors.  Biosci Biotechnol Biochem  2021  85(3):656-665  PubMed ID: 33589925   DOI: 10.1093/bbb/zbaa075
15168  Hangai S, Kawamura T, Kimura Y, Chang CY, Hibino S, Yamamoto D, Nakai Y, Tateishi R, Oshima M, Oshima H, Kodama T, Moriya K, Koike K, Yanai H, Taniguchi T.  Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells  Nat Immunol  2021  22(8):947-957  PubMed ID: 34239121   DOI: 10.1038/s41590-021-00967-5
20285  Pavillon N, Smith NI.  Deriving accurate molecular indicators of protein synthesis through Raman-based sparse classification.  Analyst  2021  146(11):3633-3641  PubMed ID: 33949431   DOI: 10.1039/d1an00412c
20313  Yamaguchi M, Takagi K, Sato M, Sato A, Miki Y, Onodera Y, Miyashita M, Sasano H, Suzuki T.  Androgens enhance the ability of intratumoral macrophages to promote breast cancer progression.  Oncol Rep  2021  46(3)  PubMed ID: 34278480   DOI: 10.3892/or.2021.8139
20315  Cheng TY, Lin YJ, Saburi W, Vieths S, Scheurer S, Schülke S, Toda M.  β-(1→4)-Mannobiose Acts as an Immunostimulatory Molecule in Murine Dendritic Cells by Binding the TLR4/MD-2 Complex.  Cells  2021  10(7)  PubMed ID: 34359943   DOI: 10.3390/cells10071774
15262  Tanikawa T, Kitamura M, Hayashi Y, Tomida N, Uwaya A, Isami F, Inoue Y.  Anti-Inflammatory Effects of Morinda citrifolia Extract against Lipopolysaccharide-Induced Inflammation in RAW264 Cells  Medicines (Basel)  2021  8(8):43  PubMed ID: 34436222   DOI: 10.3390/medicines8080043
15263  Hiromu Ito  Peroxynitrite Production Induced by LPS and X-ray Treatment Enhances Cellular Incorporation of Porphyrin in Mouse RAW264 Macrophages  Applied Sciences  2021  11:3503    DOI: 10.3390/app11083503
15264  Yamasaki M, Yamasaki Y, Furusho R, Kimura H, Kamei I, Sonoda H, Ikeda M, Oshima T, Ogawa K, Nishiyama K.  Onion ( Allium cepa L.)-Derived Nanoparticles Inhibited LPS-Induced Nitrate Production, However, Their Intracellular Incorporation by Endocytosis Was Not Involved in This Effect on RAW264 Cells  Molecules  2021  26(9):2763  PubMed ID: 34067155   DOI: 10.3390/molecules26092763
15265  Nipitpon Srimai, Wasawat Kiatarkom, Hidetake Miyata  Evaluation of the Effects of Hypo-Magnetic Fields on Mouse Macrophage RAW264 Cells  International Journal of Chemistry  2021  13:12-20    DOI: 10.5539/ijc.v13n1p12
15266  Kitazawa R, Haraguchi R, Kohara Y, Kitazawa S.  RANK- NFATc1 signaling forms positive feedback loop on rank gene expression via functional NFATc1 responsive element in rank gene promoter  Biochem Biophys Res Commun  2021  572:86-91  PubMed ID: 34358968   DOI: 10.1016/j.bbrc.2021.07.100
15267  Noguchi T, Hidaka K, Kobayashi S, Matsumoto K, Yoshioka M, Hu X, Maloney DJ, Yang SM, Kato S.  A quinazoline-based bromodomain inhibitor, CN210, ameliorates indomethacin-induced ileitis in mice by inhibiting inflammatory cytokine expression  Drug Dev Res  2021  21 Jun 1  PubMed ID: 34075610   DOI: 10.1002/ddr.21838
15268  Tsuchiya K, Hosojima S, Hara H, Kushiyama H, Mahib MR, Kinoshita T, Suda T.  Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes  Cell Rep  2021  34(12):108887  PubMed ID: 33761363   DOI: 10.1016/j.celrep.2021.108887
15269  Takahashi K, Mizukami H, Osonoi S, Ogasawara S, Hara Y, Kudoh K, Takeuchi Y, Sasaki T, Daimon M, Yagihashi S.  Inhibitory effects of xanthine oxidase inhibitor, topiroxostat, on development of neuropathy in db/db mice  Neurobiol Dis  2021  155:105392  PubMed ID: 34000416   DOI: 10.1016/j.nbd.2021.105392
15270  Shinjyo N, Nakayama H, Li L, Ishimaru K, Hikosaka K, Suzuki N, Yoshida H, Norose K.  Hypericum perforatum extract and hyperforin inhibit the growth of neurotropic parasite Toxoplasma gondii and infection-induced inflammatory responses of glial cells in vitro  J Ethnopharmacol  2021  267:113525  PubMed ID: 33129946   DOI: 10.1016/j.jep.2020.113525
15271  Kimura H, Tokuyama-Nakai S, Hirabayashi Y, Ishihara T, Jisaka M, Yokota K.  Anti-inflammatory and bioavailability studies on dietary 3,5,4'-trihydroxy-6,7-methylenedioxyflavone-O-glycosides and their aglycone from indigo leaves in a murine model of inflammatory bowel disease  J Pharm Biomed Anal   2021  193:113716  PubMed ID: 33152603   DOI: 10.1016/j.jpba.2020.113716
15272  Xi Yang, Satoru Komatsu, Sheethal Reghu, Eijiro Miyako  Optically activatable photosynthetic bacteria-based highly tumor specific immunotheranostics  Nano Today  2021  37:101100    DOI: 10.1016/j.nantod.2021.101100
15276  Yoshida H, Tsuhako R, Sugita C, Kurokawa M.  Glucosyl Hesperidin Has an Anti-diabetic Effect in High-Fat Diet-Induced Obese Mice  Biol Pharm Bull  2021  44(3):422-430  PubMed ID: 33642550   DOI: 10.1248/bpb.b20-00849
15280  Yukino Tsunekage, Masatoshi Takeiri, Yuri Yoshioka, Shinichi Matsumura, Yoshihide Kimura, Kohsuke Kataoka  Nasturtium officinale Extract Suppresses Osteoclastogenesis in RAW 264 Cells by Inhibiting IκB-Kinase β  Natural Product Communications  2021  16:1934578X2110206    DOI: 10.1177/1934578x211020643
15285  Fuchi Y, Murase H, Kai R, Kurata K, Karasawa S, Sasaki S.  Artificial Host Molecules to Covalently Capture 8-Nitro-cGMP in Neutral Aqueous Solutions and in Cells  Bioconjug Chem  2021  32(2):385-393  PubMed ID: 33529519   DOI: 10.1021/acs.bioconjchem.1c00012
20352  Takenaga K, Koshikawa N, Nagase H.  Intercellular transfer of mitochondrial DNA carrying metastasis-enhancing pathogenic mutations from high- to low-metastatic tumor cells and stromal cells via extracellular vesicles.  BMC Mol Cell Biol  2021  22(1):52  PubMed ID: 34615464   DOI: 10.1186/s12860-021-00391-5
15684  Kwaffo YA, Sarpong-Duah M, Owusu-Boateng K, Gbewonyo WS, Adjimani JP, Mosi L.  Natural antioxidants attenuate mycolactone toxicity to RAW 264.7 macrophages  Exp Biol Med (Maywood)  2021  246(17):1884-1894  PubMed ID: 34038223   DOI: 10.1177/15353702211015628
20457  Hiyoshi M, Takahashi N, Eltalkhawy YM, Noyori O, Lotfi S, Panaampon J, Okada S, Tanaka Y, Ueno T, Fujisawa JI, Sato Y, Suzuki T, Hasegawa H, Tokunaga M, Satou Y, Yasunaga JI, Matsuoka M, Utsunomiya A, Suzu S.  M-Sec induced by HTLV-1 mediates an efficient viral transmission.  PLoS Pathog  2021  17(11):e1010126  PubMed ID: 34843591   DOI: 10.1371/journal.ppat.1010126
15891  Rimpei Kamegawa, Mitsuru Naito, Satoshi Uchida, Hyun Jin Kim, Beob Soo Kim, Kanjiro Miyata  Bioinspired Silicification of mRNA-Loaded Polyion Complexes for Macrophage-Targeted mRNA Delivery  ACS Applied Bio Materials  2021  4:7790-7799  PubMed ID: 35006762   DOI: 10.1021/acsabm.1c00704
20495  Safitri FA, Tu ATT, Hoshi K, Shobo M, Zhao D, Witarto AB, Sumarsono SH, Giri-Rachman EA, Tsukakoshi K, Ikebukuro K, Yamazaki T.  Enhancement of the Immunostimulatory Effect of Phosphodiester CpG Oligodeoxynucleotides by an Antiparallel Guanine-Quadruplex Structural Scaffold.  Biomolecules  2021  11(11)  PubMed ID: 34827615   DOI: 10.3390/biom11111617
16221  Yiting Li, Litong Ban, Shili Meng, Liang Huang, Ning Sun, Hongpeng Yang, Yu Wang, Linbo Wang  Bioactivities of crude polysaccharide extracted from fermented soybean curd residue by Cordyceps militaris  Biotechnology & Biotechnological Equipment  2021  35:342-353    DOI: 10.1080/13102818.2021.1875874
16374  Xiao L, Shiwaku Y, Hamai R, Tsuchiya K, Sasaki K, Suzuki O.  Macrophage Polarization Related to Crystal Phases of Calcium Phosphate Biomaterials  Int J Mol Sci  2021  22(20):11252  PubMed ID: 34681912   DOI: 10.3390/ijms222011252
16531  Nakashima Y, Gotoh K, Mizuguchi S, Setoyama D, Takata Y, Kanno T, Kang D.  Attenuating Effect of Chlorella Extract on NLRP3 Inflammasome Activation by Mitochondrial Reactive Oxygen Species  Front Nutr  2021  8:763492  PubMed ID: 34692754   DOI: 10.3389/fnut.2021.763492
17766  Nishiguchi A, Taguchi T.  Designing an anti-inflammatory and tissue-adhesive colloidal dressing for wound treatment  Colloids Surf B Biointerfaces  2020  188:110737  PubMed ID: 32004904   DOI: 10.1016/j.colsurfb.2019.110737
17767  Yamano A, Natsume N, Yamada M, Sumimoto S, Iwasaki A, Suenaga K, Teruya T.  Irijimasides A-E, Macrolide Glycosides from an Okeania sp. Marine Cyanobacterium  J Nat Prod  2020  83(5):1585-1591  PubMed ID: 32267694   DOI: 10.1021/acs.jnatprod.0c00042
11608  Tsuhako R, Yoshida H, Sugita C, Kurokawa M.  Naringenin suppresses neutrophil infiltration into adipose tissue in high-fat diet-induced obese mice.  J Nat Med  2020  74(1):229-237.  PubMed ID: 31218550   DOI: 10.1007/s11418-019-01332-5
11704  Miori Tanaka, Ayako Sugama, Kanako Sumi, Kozue Shimizu, Yoshimi Kishimoto, Kazuo Kondo, Kaoruko Iida  Gallic acid regulates adipocyte hypertrophy and suppresses inflammatory gene expression induced by the paracrine interaction between adipocytes and macrophages in vitro and in vivo  Nutrition Research  2020  73:58-66  PubMed ID: 31841748   DOI: 10.1016/j.nutres.2019.09.007
11757  Manabe Y, Takii Y, Sugawara T.  Siphonaxanthin, a carotenoid from green algae, suppresses advanced glycation end product-induced inflammatory responses.  J Nat Med  2020  74(1):127-134  PubMed ID: 31432315   DOI: 10.1007/s11418-019-01354-z
11863  Yamada K, Takizawa S, Ohgaku Y, Asami T, Furuya K, Yamamoto K, Takahashi F, Hamajima C, Inaba C, Endo K, Matsui R, Kitamura H, Tanaka S.  MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages.  Gene  2020    PubMed ID: 31654705   DOI: 10.1016/j.gene.2019.144191
6906  Shinjyo N, Nakayama H, Ishimaru K, Hikosaka K, Mi-Ichi F, Norose K, Yoshida H.  Hypericum erectum alcoholic extract inhibits Toxoplasma growth and Entamoeba encystation: an exploratory study on the anti-protozoan potential.  J Nat Med  2020  74(1):294-305  PubMed ID: 31728823   DOI: 10.1007/s11418-019-01369-6
12001  Yoshimoto Y, Jo JI, Tabata Y.  Preparation of antibody-immobilized gelatin nanospheres incorporating a molecular beacon to visualize the biological function of macrophages.  Regen Ther  2020    PubMed ID: 31970268   DOI: 10.1016/j.reth.2019.12.009
12006  Kohara Y, Haraguchi R, Kitazawa R, Kitazawa S.  Knockdown of Lrp1 in RAW264 cells inhibits osteoclast differentiation and osteoclast-osteoblast interactions in vitro.  Biochem. Biophys. Res. Commun.  2020    PubMed ID: 31964526   DOI: 10.1016/j.bbrc.2020.01.065
12009  Bandow K, Hasegawa H, Tomomura M, Tomomura A.  Caldecrin inhibits lipopolysaccharide-induced pro-inflammatory cytokines and M1 macrophage polarization through the immunoreceptor triggering receptor expressed in myeloid cells-2.  Biochem. Biophys. Res. Commun.  2020    PubMed ID: 31973822   DOI: 10.1016/j.bbrc.2020.01.045
12016  Kawakubo M, Tanaka M, Ochi K, Watanabe A, Saka-Tanaka M, Kanamori Y, Yoshioka N, Yamashita S, Goto M, Itoh M, Shirakawa I, Kanai S, Suzuki H, Sawada M, Ito A, Ishigami M, Fujishiro M, Arima H, Ogawa Y, Suganami T.  Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects.  Sci Rep  2020    PubMed ID: 31969650   DOI: 10.1038/s41598-020-57935-6
12026  Tanaka M, Miyake H, Oka S, Maeda S, Iwasaki K, Mukai T.  Effects of charged lipids on the physicochemical and biological properties of lipid-styrene maleic acid copolymer discoidal particles.  Biochim Biophys Acta Biomembr  2020    PubMed ID: 32004520   DOI: 10.1016/j.bbamem.2020.183209
12048  Funakoshi-Tago M, Nonaka Y, Tago K, Takeda M, Ishihara Y, Sakai A, Matsutaka M, Kobata K, Tamura H.  Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2.  Sci Rep  2020    PubMed ID: 32054966   DOI: 10.1038/s41598-020-59380-x
12058  Phan TKT, Shahbazzadeh F, Kihara T.  Alpha-mangostin reduces mechanical stiffness of various cells.  Hum. Cell  2020    PubMed ID: 32078151   DOI: 10.1007/s13577-020-00330-0
12092  Kamiya Y, Kikuchi T, Goto H, Okabe I, Takayanagi Y, Suzuki Y, Sawada N, Okabe T, Suzuki Y, Kondo S, Hayashi JI, Mitani A.  IL-35 and RANKL Synergistically Induce Osteoclastogenesis in RAW264 Mouse Monocytic Cells.  Int J Mol Sci  2020    PubMed ID: 32197293   DOI: 10.3390/ijms21062069
12110  Uchikawa M, Kato M, Nagata A, Sanada S, Yoshikawa Y, Tsunematsu Y, Sato M, Suzuki T, Hashidume T, Watanabe K, Yoshikawa Y, Miyoshi N.  Elevated levels of proinflammatory volatile metabolites in feces of high fat diet fed KK-Ay mice.  Sci Rep  2020    PubMed ID: 32231228   DOI: 10.1038/s41598-020-62541-7
12126  Amlabu WE, Antwi CA, Awandare G, Gwira TM.  Elucidating the possible mechanism of action of some pathogen box compounds against Leishmania donovani.  PLoS Negl Trop Dis  2020    PubMed ID: 32275665   DOI: 10.1371/journal.pntd.0008188
12130  Sanada S, Suzuki T, Nagata A, Hashidume T, Yoshikawa Y, Miyoshi N.  Intestinal microbial metabolite stercobilin involvement in the chronic inflammation of ob/ob mice.  Sci Rep  2020    PubMed ID: 32296105   DOI: 10.1038/s41598-020-63627-y
12171  Kazunori Sasaki, Yuri Inami, Kenichi Tominaga, Hideo Kigoshi, Takashi Arimura , and Hiroko Isoda  Synthesis of 2-(2-Hydroxyethoxy)-3-hydroxysqualene and Characterization of Its Anti-Inflammatory Effects  BioMed Research International  2020    PubMed ID: 32382581   DOI: 10.1155/2020/9584567
10948  Karen Yotsumoto, Terukazu Sanui, Urara Tanaka, Hiroaki Yamato, Rehab Alshargabi, Takanori Shinjo, Yuki Nakao, Yukari Watanabe, Chikako Hayashi, Takaharu Taketomi, Takao Fukuda, Fusanori Nishimura  Amelogenin Downregulates Interferon Gamma-Induced Major Histocompatibility Complex Class II Expression Through Suppression of Euchromatin Formation in the Class II Transactivator Promoter IV Region in Macrophages  Front Immunol  2020  11:709  PubMed ID: 32373130   DOI: 10.3389/fimmu.2020.00709
12488  Takeda Y, Murata T, Jamsransuren D, Suganuma K, Kazami Y, Batkhuu J, Badral D, Ogawa H.  Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Viruses Including SARS-CoV-2  Viruses  2020  12(7):699  PubMed ID: 32605306   DOI: 10.3390/v12070699
13012  Kumagai M, Nishikawa K, Mishima T, Yoshida I, Ide M, Watanabe A, Fujita K, Morimoto Y.  Fluorinated Kavalactone Inhibited RANKL-Induced Osteoclast Differentiation of RAW264 Cells.  Biol Pharm Bull  2020    PubMed ID: 32378565   DOI: 10.1248/bpb.b20-00063
13036  Tanaka M, Sato A, Kishimoto Y, Mabashi-Asazuma H, Kondo K, Iida K.  Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes.  Nutrients  2020    PubMed ID: 32443660   DOI: 10.3390/nu12051479
13065  Crentsil JA, Yamthe LRT, Anibea BZ, Broni E, Kwofie SK, Tetteh JKA, Osei-Safo D.  Leishmanicidal Potential of Hardwickiic Acid Isolated From Croton sylvaticus.  Front Pharmacol  2020    PubMed ID: 32523532   DOI: 10.3389/fphar.2020.00753
13097  Kim Y, Wu L, Park HC, Yang HC.  Reduction of fibrous encapsulation by polyethylene glycol-grafted liposomes containing phosphatidylserine.  Biomed Mater  2020    PubMed ID: 32615550   DOI: 10.1088/1748-605X/aba238
13137  Kawata R, Oda S, Koya Y, Kajiyama H, Yokoi T.  Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production.  Toxicology  2020    PubMed ID: 32739513   DOI: 10.1016/j.tox.2020.152544
13139  Kawai K, Egami Y, Nishigaki A, Araki N.  Rab35 Targeting to the Plasma Membrane Is Dependent on the C-terminal Polybasic Cluster.  Acta Histochem Cytochem  2020    PubMed ID: 32873993   DOI: 10.1267/ahc.20-00006
13146  Ertunc N, Sato C, Kitajima K.  Sialic acid sulfation is induced by the antibiotic treatment in mammalian cells.  Biosci Biotechnol Biochem  2020    PubMed ID: 32752946   DOI: 10.1080/09168451.2020.1792763
13150  Totani H, Shinjo K, Suzuki M, Katsushima K, Mase S, Masaki A, Ito A, Ri M, Kusumoto S, Komatsu H, Ishida T, Inagaki H, Iida S, Kondo Y.  Autocrine HGF/c-Met signaling pathway confers aggressiveness in lymph node adult T-cell leukemia/lymphoma.  Oncogene  2020    PubMed ID: 32747750   DOI: 10.1038/s41388-020-01393-x
13168  Mikami A, Ogita T, Namai F, Shigemori S, Sato T, Shimosato T.  Oral administration of Flavonifractor plautii attenuates inflammatory responses in obese adipose tissue.  Mol Biol Rep  2020    PubMed ID: 32808115   DOI: 10.1007/s11033-020-05727-6
13180  Wada S, Kanzaki H, Katsumata Y, Yamaguchi Y, Narimiya T, Attucks OC, Nakamura Y, Tomonari H.  Bach1 Inhibition Suppresses Osteoclastogenesis via Reduction of the Signaling via Reactive Oxygen Species by Reinforced Antioxidation.  Front Cell Dev Biol  2020    PubMed ID: 32850850   DOI: 10.3389/fcell.2020.00740
13258  Takeuchi T, Horimoto Y, Oyama M, Nakatani S, Kobata K, Tamura M, Arata Y, Hatanaka T.  Osteoclast Differentiation Is Suppressed by Increased O-GlcNAcylation Due to Thiamet G Treatment.  Biol Pharm Bull  2020    PubMed ID: 32999159   DOI: 10.1248/bpb.b20-00221
13294  Nishigaki C, Nakayama M, Miyata H.  Cell physiological responses of RAW264 macrophage cells to a 50-Hz magnetic field.  Int J Radiat Biol  2020    PubMed ID: 33052723   DOI: 10.1080/09553002.2020.1837983
13298  Yang X, Sasano T, Ebana Y, Takeuchi JK, Ihara K, Yamazoe M, Furukawa T.  Functional Role of the L396R Mutation of Tks5 Identified by an Exome-Wide Association Study in Atrial Fibrillation.  Circ J  2020    PubMed ID: 33087629   DOI: 10.1253/circj.CJ-20-0101
13324  Yahiro K, Ogura K, Goto Y, Iyoda S, Kobayashi T, Takeuchi H, Ohnishi M, Moss J.  Subtilase cytotoxin induces a novel form of Lipocalin 2, which promotes Shiga-toxigenic Escherichia coli survival.  Sci Rep  2020    PubMed ID: 33144618   DOI: 10.1038/s41598-020-76027-z
13341  Matur M, Madhyastha H, Shruthi TS, Madhyastha R, Srinivas SP, Navya PN, Daima HK.  Engineering bioactive surfaces on nanoparticles and their biological interactions.  Sci Rep  2020    PubMed ID: 33184324   DOI: 10.1038/s41598-020-75465-z
13434  Frederick Ayertey, Ebenezer Ofori-Attah, Stephen Antwi, Michael Amoa-Bosompem, Georgina Djameh, Nathaniel Lartey Lartey, Mistuko Ohashi, Kwadwo Asamoah Kusi, Alfred Ampomah Appiah, Regina Appiah-Opong, Laud Kenneth Okine  Anti-inflammatory activity and mechanism of action of ethanolic leaf extract of Morinda lucida Benth  Journal of Traditional and Complementary Medicine  2020    PubMed ID: 34012871   DOI: 10.1016/j.jtcme.2020.07.001
13492  Masanori HASHIMOTO, Haruaki KITAGAWA, Yusuke TAKAHASHI, Mikako HAYASHI, Satoshi IMAZATO  Cytotoxicity of S-PRG Fillers: Direct Exposure of Fillers and Eluates from the Fillers to RAW264 Cells  Nano Biomedicine  2020  12:3-10    DOI: 10.11344/nano.12.3
13545  Quan H, Kim Y, Wu L, Park HC, Yang HC.  Modulation of Macrophage Polarization by Phospholipids on the Surface of Titanium  Molecules  2020  25(11):2700  PubMed ID: 32532146   DOI: 10.3390/molecules25112700
13614  Kuramoto M, Kawashima N, Tazawa K, Nara K, Fujii M, Noda S, Hashimoto K, Nozaki K, Okiji T.  Mineral trioxide aggregate suppresses pro-inflammatory cytokine expression via the calcineurin/nuclear factor of activated T cells/early growth response 2 pathway in lipopolysaccharide-stimulated macrophages  Int Endod J  2020  53(12):1653-1665  PubMed ID: 32767860   DOI: 10.1111/iej.13386
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16816  Chie Kojima, Risa Katayama, Thi Lien Nguyen, Yuto Oki, Ayako Tsujimoto, Shin-ichi Yusa, Kohei Shiraishi, Akikazu Matsumoto  Different antifouling effects of random and block copolymers comprising 2-methacryloyloxyethyl phosphorylcholine and dodecyl methacrylate  European Polymer Journal  2020  136:109932    DOI: 10.1016/j.eurpolymj.2020.109932
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5357  Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.  AUTACs: Cargo-Specific Degraders Using Selective Autophagy.  Mol Cell  2019  76(5):797-810  PubMed ID: 31606272   DOI: 10.1016/j.molcel.2019.09.009
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11539  Suzuka H, Mimura A, Inaoka Y, Murase K.  Magnetic Nanoparticles in Macrophages and Cancer Cells Exhibit Different Signal Behavior on Magnetic Particle Imaging.  J Nanosci Nanotechnol  2019    PubMed ID: 31039837   DOI: 10.1166/jnn.2019.16619
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10569  Yamaguchi Y, Kanzaki H, Katsumata Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.  Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation.  J. Cell. Mol. Med.  2018  22:1138-1147  PubMed ID: 29063666   DOI: 10.1111/jcmm.13367
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10645  Nagahara H, Seno T, Yamamoto A, Obayashi H, Inoue T, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y.  Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.  Biochem. Biophys. Res. Commun.  2018  495:1901-1907  PubMed ID: 29225172   DOI: 10.1016/j.bbrc.2017.12.035
10696  Kumagai M, Watanabe A, Yoshida I, Mishima T, Nakamura M, Nishikawa K, Morimoto Y.  Evaluation of Aculeatin and Toddaculin Isolated from Toddalia asiatica as Anti-inflammatory Agents in LPS-Stimulated RAW264 Macrophages.  Biol. Pharm. Bull.  2018  41:132-137  PubMed ID: 29311475   DOI: 10.1248/bpb.b17-00607
10708  Kon R, Tsubota Y, Minami M, Kato S, Matsunaga Y, Kimura H, Murakami Y, Fujikawa T, Sakurai R, Tomimoto R, Machida Y, Ikarashi N, Sugiyama K.  CPT-11-Induced Delayed Diarrhea Develops via Reduced Aquaporin-3 Expression in the Colon.  Int J Mol Sci  2018  19:  PubMed ID: 29316651   DOI: 10.3390/ijms19010170
10711  Egami Y, Araki N.  Transient recruitment of M-Ras GTPase to phagocytic cups in RAW264 macrophages during FcγR-mediated phagocytosis.  Microscopy (Oxf)  2018  67:68-74  PubMed ID: 29340604   DOI: 10.1093/jmicro/dfx131
10714  Tsukayama I, Toda K, Takeda Y, Mega T, Tanaka M, Kawakami Y, Takahashi Y, Kimoto M, Yamamoto K, Miki Y, Murakami M, Suzuki-Yamamoto T.  Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway.  J Clin Biochem Nutr  2018  62:139-147  PubMed ID: 29610553   DOI: 10.3164/jcbn.17-54
10782  Miyashita T, Minami K, Ito M, Koizumi R, Sagane Y, Watanabe T, Niwa K.  Emu Oil Reduces LPS-Induced Production of Nitric Oxide and TNF-α but not Phagocytosis in RAW 264 Macrophages.  J Oleo Sci  2018  67:471-477  PubMed ID: 29526880   DOI: 10.5650/jos.ess17228
10790  El-Desoky AH, Abdel-Rahman RF, Ahmed OK, El-Beltagi HS, Hattori M.  Anti-inflammatory and antioxidant activities of naringin isolated from Carissa carandas L.: In vitro and in vivo evidence.  Phytomedicine  2018  42:126-134  PubMed ID: 29655678   DOI: 10.1016/j.phymed.2018.03.051
10799  Kawai C, Yamauchi A, Kuribayashi F.  Monoclonal antibody 7D5 recognizes the R147 epitope on the gp91phox , phagocyte flavocytochrome b558 large subunit.  Microbiol. Immunol.  2018  62:269-280  PubMed ID: 29573449   DOI: 10.1111/1348-0421.12584
11027  Miyake T, Miyake T, Sakaguchi M, Nankai H, Nakazawa T, Morishita R.  Prevention of Asthma Exacerbation in a Mouse Model by Simultaneous Inhibition of NF-kB and STAT6 Activation Using a Chimeric Decoy Strategy  Mol Ther Nucleic Acids  2018  10:159-169  PubMed ID: 29499930   DOI: 10.1016/j.omtn.2017.12.005
11198  Ikebuchi Y, Aoki S, Honma M, Hayashi M, Sugamori Y, Khan M, Kariya Y, Kato G, Tabata Y, Penninger JM, Udagawa N, Aoki K, Suzuki H.  Coupling of bone resorption and formation by RANKL reverse signalling.  Nature  2018  561(7722):195-200  PubMed ID: 30185903   DOI: 10.1038/s41586-018-0482-7
4050  Mukai Y, Yamanishi R.  Retinol but not retinoic acid can enhance the glutathione level, in a manner similar to β-carotene, in a murine cultured macrophage cell line.  Food Sci Nutr  2018    PubMed ID: 30258608   DOI: 10.1002/fsn3.726
11098  Ali MFZ, Yasin IA, Ohta T, Hashizume A, Ido A, Takahashi T, Miura C, Miura T.  The silkrose of Bombyx mori effectively prevents vibriosis in penaeid prawns via the activation of innate immunity.  Sci Rep  2018  8(1):8836  PubMed ID: 29892000   DOI: 10.1038/s41598-018-27241-3
11116  Tasaka T, Kuwada E, Izuchi Y, Nishigawa R, Yamada H, Unuma H, Tokunaga K, Hayakawa A, Go A, Go K, Uto Y.  Concentration-dependent Activation of Inflammatory/Anti-inflammatory Functions of Macrophages by Hydrolyzed Whey Protein.  Anticancer Res.  2018  38(7):4299-4304  PubMed ID: 29970565   DOI: 10.21873/anticanres.12728
11122  Sakoda M, Kaneko M, Ohta S, Qi P, Ichimura S, Yatomi Y, Ito T.  Injectable Hemostat Composed of a Polyphosphate-Conjugated Hyaluronan Hydrogel.  Biomacromolecules  2018  19(8):3280-3290  PubMed ID: 29985587   DOI: 10.1021/acs.biomac.8b00588
11186  Kawasaki K, Okuda-Hanafusa C, Aoyagi M, Taoka K, Yamamoto N, Muroyama K, Murosaki S, Yamamoto Y.  Inhibitory effect of the compounds from the water extract of Curcuma longa on the production of PGE2 and NO in a macrophage cell line stimulated by LPS.  Biosci. Biotechnol. Biochem.  2018  82(12):2109-2117  PubMed ID: 30146952   DOI: 10.1080/09168451.2018.1511366
11200  Odkhuu E, Komatsu T, Koide N, Naiki Y, Takeuchi K, Tanaka Y, Tsolmongyn B, Jambalganiin U, Morita N, Yoshida T, Gotoh B, Yokochi T.  Sendai virus C protein limits NO production in infected RAW264.7 macrophages.  Innate Immun  2018  24(7):430-438  PubMed ID: 30189760   DOI: 10.1177/1753425918796619
11074  Tsukamoto H, Takeuchi S, Kubota K, Kobayashi Y, Kozakai S, Ukai I, Shichiku A, Okubo M, Numasaki M, Kanemitsu Y, Matsumoto Y, Nochi T, Watanabe K, Aso H, Tomioka Y.  Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKK?-IRF3 axis activation.  J. Biol. Chem.  2018  293(26):10186-10201  PubMed ID: 29760187   DOI: 10.1074/jbc.M117.796631
11112  Niino T, Tago K, Yasuda D, Takahashi K, Mashino T, Tamura H, Funakoshi-Tago M.  A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis.  Biochem. Pharmacol.  2018  155:182-197  PubMed ID: 29940171   DOI: 10.1016/j.bcp.2018.06.021
11249  Kamiya T, Tanimoto Y, Fujii N, Negishi T, Suzuki T, Hatano T, Arimoto-Kobayashi S.  2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae.  Food Chem. Toxicol.  2018    PubMed ID: 30316843   DOI: 10.1016/j.fct.2018.10.028
11493  Katsumata Y, Kanzaki H, Honda Y, Tanaka T, Yamaguchi Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.  Single Local Injection of Epigallocatechin Gallate-Modified Gelatin Attenuates Bone Resorption and Orthodontic Tooth Movement in Mice.  Polymers (Basel)  2018  10(12)  PubMed ID: 30961309   DOI: 10.3390/polym10121384
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4441  Seisho Azuma, Yoshinobu Murakami, Eiko Azuma, Kimiye Baba, Masahiko Taniguchi  Anti-inflammatory effects of flavonoids in Citrus jabara fruit peels  Trends in Immunotherapy  2018  2    DOI: 10.24294/ti.v2.i2.844
4324  Quan H, Kim Y, Park HC, Yang HC.  Effects of phosphatidylserine-containing supported lipid bilayers on the polarization of macrophages.  J Biomed Mater Res A  2018    PubMed ID: 29781181   DOI: 10.1002/jbm.a.36454
4325  Hoshi K, Yamazaki T, Yoshikawa C, Tsugawa W, Ikebukuro K, Sode K.  Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production.  Int J Nanomedicine  2018    PubMed ID: 30122920   DOI: 10.2147/IJN.S166259
4326  Saiki P, Nakajima Y, Van Griensven LJLD, Miyazaki K.  Real-time monitoring of IL-6 and IL-10 reporter expression for anti-inflammation activity in live RAW 264.7 cells.  Biochem. Biophys. Res. Commun.  2018    PubMed ID: 30301531   DOI: 10.1016/j.bbrc.2018.09.173
4327  Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Tanimoto K.  Dynamic imaging of the effect of mesenchymal stem cells on osteoclast precursor cell chemotaxis for bone defects in the mouse skull.  J Dent Sci  2018    PubMed ID: 30895145   DOI: 10.1016/j.jds.2018.08.001
4328  Sumi K, Abe T, Kunimatsu R, Oki N, Tsuka Y, Awada T, Nakajima K, Ando K, Tanimoto K.  The effect of mesenchymal stem cells on chemotaxis of osteoclast precursor cells.  J Oral Sci  2018    PubMed ID: 29925706   DOI: 10.2334/josnusd.17-0187
4329  Kajita T, Ariyoshi W, Okinaga T, Mitsugi S, Tominaga K, Nishihara T.  Mechanisms involved in enhancement of osteoclast formation by activin-A.  J. Cell. Biochem.  2018    PubMed ID: 29737562   DOI: 10.1002/jcb.26906
4330  Sakamoto T, Ohashi W, Tomita K, Hattori K, Matsuda N, Hattori Y.  Anti-inflammatory properties of cilostazol: Its interruption of DNA binding activity of NF-κB from the Toll-like receptor signaling pathways.  Int. Immunopharmacol.  2018    PubMed ID: 30005227   DOI: 10.1016/j.intimp.2018.06.021
4331  El-Beih AA, El-Desoky AH, Al-Hammady MA, Elshamy AI, Hegazy MF, Kato H, Tsukamoto S.  New inhibitors of RANKL-induced Osteoclastogenesis from the marine sponge Siphonochalina siphonella.  Fitoterapia  2018    PubMed ID: 29729401   DOI: 10.1016/j.fitote.2018.05.001
4332  Tanaka M, Kishimoto Y, Sasaki M, Sato A, Kamiya T, Kondo K, Iida K.  Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways.  Oxid Med Cell Longev  2018    PubMed ID: 30533177   DOI: 10.1155/2018/9364364
4333  Kawabata K, Baba N, Sakano T, Hamano Y, Taira S, Tamura A, Baba S, Natsume M, Ishii T, Murakami S, Ohigashi H.  Functional properties of anti-inflammatory substances from quercetin-treated Bifidobacterium adolescentis.  Biosci. Biotechnol. Biochem.  2018    PubMed ID: 29165050   DOI: 10.1080/09168451.2017.1401916
4334  Fukai E, Sato H, Watanabe M, Nakae D, Totsuka Y.  Establishment of an in vivo simulating co-culture assay platform for genotoxicity of multi-walled carbon nanotubes.  Cancer Sci.  2018    PubMed ID: 29444368   DOI: 10.1111/cas.13534
4335  Hussain Z, Uyama T, Kawai K, Binte Mustafiz SS, Tsuboi K, Araki N, Ueda N.  Phosphatidylserine-stimulated production of N-acyl-phosphatidylethanolamines by Ca2+-dependent N-acyltransferase.  Biochim Biophys Acta Mol Cell Biol Lipids  2018    PubMed ID: 29447909   DOI: 10.1016/j.bbalip.2018.02.002
4336  Takahashi S, Sakamaki M, Ferdousi F, Yoshida M, Demura M, Watanabe MM, Isoda H.  Ethanol Extract of Aurantiochytrium mangrovei 18W-13a Strain Possesses Anti-inflammatory Effects on Murine Macrophage RAW264 Cells.  Front Physiol  2018    PubMed ID: 30319432   DOI: 10.3389/fphys.2018.01205
4496  Su YW, Chim SM, Zhou L, Hassanshahi M, Chung R, Fan C, Song Y, Foster BK, Prestidge CA, Peymanfar Y, Tang Q, Butler LM, Gronthos S, Chen D, Xie Y, Chen L, Zhou XF, Xu J, Xian CJ.  Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats.  Bone  2018  116:232-247  PubMed ID: 30125729   DOI: 10.1016/j.bone.2018.08.010
4497  Kuroda C, Ueda K, Haniu H, Ishida H, Okano S, Takizawa T, Sobajima A, Kamanaka T, Yoshida K, Okamoto M, Tsukahara T, Matsuda Y, Aoki K, Kato H, Saito N.  Different aggregation and shape characteristics of carbon materials affect biological responses in RAW264 cells.  Int J Nanomedicine  2018  13:6079-6088  PubMed ID: 30323595   DOI: 10.2147/IJN.S172493
4498  Momozane T, Kawamura T, Itoh Y, Sanosaka M, Sasaki T, Kanzaki R, Ose N, Funaki S, Shintani Y, Minami M, Okumura M, Takemori H.  Carnosol suppresses interleukin-6 production in mouse lungs injured by ischemia-reperfusion operation and in RAW264.7 macrophages treated with lipopolysaccharide.  Biochem. Cell Biol.  2018  96(6):769-776  PubMed ID: 29958095   DOI: 10.1139/bcb-2017-0339
4499  Choodej S, Pudhom K, Mitsunaga T.  Inhibition of TNF-α-Induced Inflammation by Sesquiterpene Lactones from Saussurea lappa and Semi-Synthetic Analogues.  Planta Med.  2018  84(5):329-335  PubMed ID: 28962049   DOI: 10.1055/s-0043-120115
14915  Komatsu W, Kishi H, Yagasaki K, Ohhira S.  Urolithin A attenuates pro-inflammatory mediator production by suppressing PI3-K/Akt/NF-κB and JNK/AP-1 signaling pathways in lipopolysaccharide-stimulated RAW264 macrophages: Possible involvement of NADPH oxidase-derived reactive oxygen species  Eur J Pharmacol  2018  833:411-424  PubMed ID: 29932926   DOI: 10.1016/j.ejphar.2018.06.023
15294  Pavillon N, Hobro AJ, Akira S, Smith NI.  Noninvasive detection of macrophage activation with single-cell resolution through machine learning  Proc Natl Acad Sci U S A  2018  115(12):E2676-E2685  PubMed ID: 29511099   DOI: 10.1073/pnas.1711872115
7036  Komiya C, Tanaka M, Tsuchiya K, Shimazu N, Mori K, Furuke S, Miyachi Y, Shiba K, Yamaguchi S, Ikeda K, Ochi K, Nakabayashi K, Hata KI, Itoh M, Suganami T, Ogawa Y.  Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis.  Sci Rep  2017  7:44754  PubMed ID: 28303974   DOI: 10.1038/srep44754
9723  Iwazaki K, Tanaka T, Hozumi Y, Okada M, Tsuchiya R, Iseki K, Topham MK, Kawamae K, Takagi M, Goto K.  DGKζ Downregulation Enhances Osteoclast Differentiation and Bone Resorption Activity Under Inflammatory Conditions.  J. Cell. Physiol.  2017  232:617-624  PubMed ID: 27312515   DOI: 10.1002/jcp.25461
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9964  Shirasugi M, Nishioka K, Yamamoto T, Nakaya T, Kanamura N.  Normal human gingival fibroblasts undergo cytostasis and apoptosis after long-term exposure to butyric acid.  Biochem. Biophys. Res. Commun.  2017  482:1122-1128  PubMed ID: 27914813   DOI: 10.1016/j.bbrc.2016.11.168
10001  Quan H, Park HC, Kim Y, Yang HC.  Modulation of the anti-inflammatory effects of phosphatidylserine-containing liposomes by PEGylation.  J Biomed Mater Res A  2017  105:1479-1486  PubMed ID: 27998010   DOI: 10.1002/jbm.a.35981
10074  Takano A, Fukuda T, Shinjo T, Iwashita M, Matsuzaki E, Yamamichi K, Takeshita M, Sanui T, Nishimura F.  Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation.  Metab. Clin. Exp.  2017  69:157-170  PubMed ID: 28285646   DOI: 10.1016/j.metabol.2017.01.006
10085  Ariyoshi W, Okinaga T, Chaweewannakorn W, Akifusa S, Nisihara T.  Mechanisms involved in enhancement of matrix metalloproteinase-9 expression in macrophages by interleukin-33.  J. Cell. Physiol.  2017  232:3481-3495  PubMed ID: 28105703   DOI: 10.1002/jcp.25809
10122  Taniguchi M, Ochiai A, Toyoda R, Sato T, Saitoh E, Kato T, Tanaka T.  Effects of arginine and leucine substitutions on anti-endotoxic activities and mechanisms of action of cationic and amphipathic antimicrobial octadecapeptide from rice α-amylase.  J. Pept. Sci.  2017  23:252-260  PubMed ID: 28185358   DOI: 10.1002/psc.2983
10165  Takeuchi T, Sugimoto A, Imazato N, Tamura M, Nakatani S, Kobata K, Arata Y.  Glucosamine Suppresses Osteoclast Differentiation through the Modulation of Glycosylation Including O-GlcNAcylation.  Biol. Pharm. Bull.  2017  40:352-356  PubMed ID: 28250278   DOI: 10.1248/bpb.b16-00877
10169  Zhang J, Hiromoto S, Yamazaki T, Huang H, Jia G, Li H, Yuan G.  Macrophage phagocytosis of biomedical Mg alloy degradation products prepared by electrochemical method.  Mater Sci Eng C Mater Biol Appl  2017  75:1178-1183  PubMed ID: 28415404   DOI: 10.1016/j.msec.2017.02.126
10190  Ichimura K, Shimizu T, Matsumoto A, Hirai S, Yokoyama E, Takeuchi H, Yahiro K, Noda M.  Nitric oxide-enhanced Shiga toxin production was regulated by Fur and RecA in enterohemorrhagic Escherichia coli O157.  Microbiologyopen  2017  6:  PubMed ID: 28294553   DOI: 10.1002/mbo3.461
10215  Yamagata Y, Tomioka H, Sakamoto K, Sato K, Harada H, Ikeda T, Kayamori K.  CD163-Positive Macrophages Within the Tumor Stroma Are Associated With Lymphangiogenesis and Lymph Node Metastasis in Oral Squamous Cell Carcinoma.  J. Oral Maxillofac. Surg.  2017  75:2144-2153  PubMed ID: 28399391   DOI: 10.1016/j.joms.2017.03.009
10230  Hashiguchi A, Hitachi K, Zhu W, Tian J, Tsuchida K, Komatsu S.  Mung bean (Vigna radiata (L.)) coat extract modulates macrophage functions to enhance antigen presentation: A proteomic study.  J Proteomics  2017  161:26-37  PubMed ID: 28373035   DOI: 10.1016/j.jprot.2017.03.025
10285  Fereig RM, Kuroda Y, Terkawi MA, Mahmoud ME, Nishikawa Y.  Immunization with Toxoplasma gondii peroxiredoxin 1 induces protective immunity against toxoplasmosis in mice.  PLoS ONE  2017  12:e0176324  PubMed ID: 28448521   DOI: 10.1371/journal.pone.0176324
10288  Kato T, Toyooka T, Ibuki Y, Masuda S, Watanabe M, Totsuka Y.  Effect of physicochemical character differences on the genotoxic potency of kaolin.  Genes Environ  2017  39:12  PubMed ID: 28469735   DOI: 10.1186/s41021-017-0075-y
10335  Wu S, Yano S, Chen J, Hisanaga A, Sakao K, He X, He J, Hou DX.  Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-Induced Inflammation through Dual Modulation of Inflammatory and Antioxidant Mediators.  J. Agric. Food Chem.  2017  65:5133-5141  PubMed ID: 28573848   DOI: 10.1021/acs.jafc.7b01599
10380  Murata K, Motomura Y, Tanaka T, Kanno S, Yano T, Onimaru M, Shimoyama A, Nishio H, Sakai Y, Oh-Hora M, Hara H, Fukase K, Takada H, Masuda S, Ohga S, Yamasaki S, Hara T.  Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease.  Clin. Exp. Immunol.  2017  190:54-67  PubMed ID: 28640392   DOI: 10.1111/cei.13002
10551  Saiki P, Kawano Y, Van Griensven LJLD, Miyazaki K.  The anti-inflammatory effect of Agaricus brasiliensis is partly due to its linoleic acid content.  Food Funct  2017  8:4150-4158  PubMed ID: 29022634   DOI: 10.1039/c7fo01172e
10704  Hanagata N, Li X, Chen MH, Li J, Hattori S.  Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities.  Int J Nanomedicine  2017  13:43-62  PubMed ID: 29317815   DOI: 10.2147/IJN.S152141
10915    Effect of Particle Size of Gold Nanoparticles on Matrix Metalloprotease Inhibition, Cytotoxicity and Genotoxicity  Journal of Biomaterials and Tissue Engineering,  2017  7, 139-146    DOI: 10.1166/jbt.2017.1555
10949    Effect of 50-Hz Sinusoidal Magnetic Field on the Production of Superoxide Anion and the Expression of Heat-shock Protein 70 in RAW264 Cells  International Journal of Chemistry  2017  9    DOI: 10.5539/ijc.v9n2p23
4526  Yusuke Hiraku, Yoshihiro Nishikawa, Ning Ma, Tahmina Afroza, Kosuke Mizobuchi, Ryo Ishiyama, Yuta Matsunaga, Takamichi Ichinose, Shosuke Kawanishi, Mariko Murata  Nitrative DNA damage induced by carbon-black nanoparticles in macrophages and lung epithelial cells  Mutation Research/Genetic Toxicology and Environmental Mutagenesis  2017  818, 7-16  PubMed ID: 28477879   DOI: 10.1016/j.mrgentox.2017.04.002
6471  Horigome S, Yoshida I, Ito S, Inohana S, Fushimi K, Nagai T, Yamaguchi A, Fujita K, Satoyama T, Katsuda SI, Suzuki S, Watai M, Hirose N, Mitsue T, Shirakawa H, Komai M.  Inhibitory effects of Kaempferia parviflora extract on monocyte adhesion and cellular reactive oxygen species production in human umbilical vein endothelial cells.  Eur J Nutr  2017  56(3):949-964  PubMed ID: 26704713   DOI: 10.1007/s00394-015-1141-5
9460  Nan Ma, Di Yang, Hirohiko Okamura, Jumpei Teramachi, Tomokazu Hasegawa, Lihong Qiu, Tatsuji Haneji  Involvement of interleukin‑23 Induced by Porphyromonas Endodontalis Lipopolysaccharide in Osteoclastogenesis  Mol Med Rep  2017  15(2):559-566  PubMed ID: 28000855   DOI: 10.3892/mmr.2016.6041
10050  Ha-Eun Yang, Yongjia Li, Akira Nishimura, Huei-Fen Jheng, Ana Yuliana, Ryuji Kitano-Ohue, Wataru Nomura, Nobuyuki Takahashi, Chu-Sook Kim, Rina Yu, Nahoko Kitamura, Si-Bum Park, Shigenobu Kishino, Jun Ogawa, Teruo Kawada, Tsuyoshi Goto  Synthesized Enone Fatty Acids Resembling Metabolites From Gut Microbiota Suppress Macrophage-Mediated Inflammation in Adipocytes  Mol Nutr Food Res  2017  Oct;61(10)  PubMed ID: 28544341   DOI: 10.1002/mnfr.201700064
10076  Yusuke Kono, Taketo Nakai, Hitomi Taguchi, Takuya Fujita  Development of Magnetic Anionic Liposome/Atelocollagen Complexes for Efficient Magnetic Drug Targeting  Drug Deliv  2017  24(1):1740-1749  PubMed ID: 29141461   DOI: 10.1080/10717544.2017.1402219
12320  Masayori Hagimori, Eri Hatabe, Kohei Sano, Hirotaka Miyazaki, Hitoshi Sasaki, Hideo Saji, Takahiro Mukai  An Activatable Fluorescent γ-Polyglutamic Acid Complex for Sentinel Lymph Node Imaging  Biol Pharm Bull  2017  40(3):297-302  PubMed ID: 28250270   DOI: 10.1248/bpb.b16-00773
14213  Into T, Horie T, Inomata M, Gohda J, Inoue JI, Murakami Y, Niida S.  Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88  Sci Rep  2017  7(1):1009  PubMed ID: 28432355   DOI: 10.1038/s41598-017-01246-w
14216  Horiuchi T, Sakata N, Narumi Y, Kimura T, Hayashi T, Nagano K, Liu K, Nishibori M, Tsukita S, Yamada T, Katagiri H, Shirakawa R, Horiuchi H.  Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity  J Biol Chem  2017  292(20):8436-8446  PubMed ID: 28373282   DOI: 10.1074/jbc.M116.769380
14220  Wang J, Ayano E, Maitani Y, Kanazawa H.  Tunable Surface Properties of Temperature-Responsive Polymer-Modified Liposomes Induce Faster Cellular Uptake  ACS Omega  2017  ;2(1):316-325  PubMed ID: 31457232   DOI: 10.1021/acsomega.6b00342
14255  Komatsu W, Itoh K, Akutsu S, Kishi H, Ohhira S.  Nasunin inhibits the lipopolysaccharide-induced pro-inflammatory mediator production in RAW264 mouse macrophages by suppressing ROS-mediated activation of PI3 K/Akt/NF-κB and p38 signaling pathways  Biosci Biotechnol Biochem  2017  1956-1966  PubMed ID: 28812425   DOI: 10.1080/09168451.2017.1362973
14379  Okabe I, Kikuchi T, Mogi M, Takeda H, Aino M, Kamiya Y, Fujimura T, Goto H, Okada K, Hasegawa Y, Noguchi T, Mitani A.  IL-15 and RANKL Play a Synergistically Important Role in Osteoclastogenesis  J Cell Biochem  2017  118(4):739-747  PubMed ID: 27608420   DOI: 10.1002/jcb.25726
14456  Yokota S, Chosa N, Kyakumoto S, Kimura H, Ibi M, Kamo M, Satoh K, Ishisaki A.  ROCK/actin/MRTF signaling promotes the fibrogenic phenotype of fibroblast-like synoviocytes derived from the temporomandibular joint  Int J Mol Med  2017  39(4):799-808  PubMed ID: 28259960   DOI: 10.3892/ijmm.2017.2896
14479  Nishina A, Shimizu K, Koketsu M, Ninomiya M, Sato D, Suzuki T, Hayakawa S, Kimura H.  5,7-Dihydroxyflavone Analogues May Regulate Lipopolysaccharide-Induced Inflammatory Responses by Suppressing I κ B α-Linked Akt and ERK5 Phosphorylation in RAW 264.7 Macrophages  Evid Based Complement Alternat Med  2017  7898973  PubMed ID: 28539967   DOI: 10.1155/2017/7898973
14480  Li G, Miura K, Kuno M.  Extracellular phosphates enhance activities of voltage-gated proton channels and production of reactive oxygen species in murine osteoclast-like cells  Pflugers Arch  2017  469(2):279-292  PubMed ID: 27999941   DOI: 10.1007/s00424-016-1931-5
14565  Igeta K, Kuwamura Y, Horiuchi N, Nozaki K, Shiraishi D, Aizawa M, Hashimoto K, Yamashita K, Nagai A.  Morphological and functional changes in RAW264 macrophage-like cells in response to a hydrated layer of carbonate-substituted hydroxyapatite  J Biomed Mater Res A  2017  105(4):1063-1070  PubMed ID: 28085214   DOI: 10.1002/jbm.a.35997
14570  Differential Regulation of IL-1β and IL-6 Release in Murine Macrophages  Differential Regulation of IL-1β and IL-6 Release in Murine Macrophages  Inflammation  2017  40(6):1933-1943  PubMed ID: 28766178   DOI: 10.1007/s10753-017-0634-1
14571  Takakuwa S, Mizuno N, Takano T, Asakawa S, Sato T, Hiratsuka M, Hirasawa N.  Down-regulation of Na +/H + exchanger 1 by Toll-like receptor stimulation in macrophages  Immunobiology  2017  222(2):176-182  PubMed ID: 27771174   DOI: 10.1016/j.imbio.2016.10.005
14572  Kanaoka Y, Koga M, Sugiyama K, Ohishi K, Kataoka Y, Yamauchi A.  Varenicline enhances oxidized LDL uptake by increasing expression of LOX-1 and CD36 scavenger receptors through α 7 nAChR in macrophages  Toxicology  2017  380:62-7  PubMed ID: 28202387   DOI: 10.1016/j.tox.2017.02.006
14656  Tanaka KI, Sugizaki T, Kanda Y, Tamura F, Niino T, Kawahara M  Preventive Effects of Carnosine on Lipopolysaccharide-induced Lung Injury  Sci Rep  2017  7:42813  PubMed ID: 28205623   DOI: 10.1038/srep42813
14714  Ikeda Y, Kawai K, Ikawa A, Kawamoto K, Egami Y, Araki N.  Rac1 switching at the right time and location is essential for Fcγ receptor-mediated phagosome formation  J Cell Sci  2017  130(15):2530-2540  PubMed ID: 28600322   DOI: 10.1242/jcs.201749
14725  Minegishi S, Yumura A, Miyoshi H, Negi S, Taketani S, Motterlini R, Foresti R, Kano K, Kitagishi H.  Detection and Removal of Endogenous Carbon Monoxide by Selective and Cell-Permeable Hemoprotein Model Complexes  J Am Chem Soc  2017  139(16):5984-5991  PubMed ID: 28388069   DOI: 10.1021/jacs.7b02229
14773  Yokota H, Tsuzuki A, Shimada Y, Imai A, Utsumi D, Tsukahara T, Matsumoto M, Amagase K, Iwata K, Nakamura A, Yabe-Nishimura C, Kato S.  NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid-Induced Murine Colitis  J Pharmacol Exp Ther  2017  360(1):192-200  PubMed ID: 27754929   DOI: 10.1124/jpet.116.235580
15301  Hayashi K, Sato Y, Maruoka H, Sakamoto W, Yogo T.  Organic-Inorganic Hybrid Nanoparticles for Tracking the Same Cells Seamlessly at the Cellular, Tissue, and Whole Body Levels  ACS Biomater Sci Eng  2017  3(6):1129-1135  PubMed ID: 33429587   DOI: 10.1021/acsbiomaterials.7b00181
7077  Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake K, Takatsu K.  Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice.  Sci Rep  2016  6:23097  PubMed ID: 26975571   DOI: 10.1038/srep23097
7094  Ryohei Hamaguchi, Yukihiro Kuroda  A Novel Biomarker for Cellular Toxicity and Phospholipid Accumulation by Cationic Amphiphilic Drugs.  Chromatography  2016  37:35-38    DOI: 10.15583/jpchrom.2015.033
7119  Taniguchi M, Ochiai A, Matsushima K, Tajima K, Kato T, Saitoh E, Tanaka T.  Endotoxin-neutralizing activity and mechanism of action of a cationic α-helical antimicrobial octadecapeptide derived from α-amylase of rice.  Peptides  2016  75:101-8  PubMed ID: 26643956   DOI: 10.1016/j.peptides.2015.11.006
7148  Ohta T, Kusano K, Ido A, Miura C, Miura T.  Silkrose: A novel acidic polysaccharide from the silkmoth that can stimulate the innate immune response.  Carbohydr Polym  2016  136:995-1001  PubMed ID: 26572439   DOI: 10.1016/j.carbpol.2015.09.070
7157  Higuchi H, Shoji T, Murase Y, Iijima S, Nishijima K.  Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264.  Biosci. Biotechnol. Biochem.  2016  80:501-9  PubMed ID: 26540411   DOI: 10.1080/09168451.2015.1104238
7230  Takayama S, Hashimoto K, Kokubu E, Taniguchi M, Tajima K, Ochiai A, Saitoh E, Saito A, Ishihara K, Kato T.  Inhibitory effects of a novel cationic dodecapeptide [CL(14-25)] derived from cyanate lyase of rice on endotoxic activities of LPSs from Escherichia coli and periodontopathic Aggregatibacter actinomycetemcomitans.  Microb. Pathog.  2016  94:2-11  PubMed ID: 26318142   DOI: 10.1016/j.micpath.2015.08.011
7469  Hashimoto M, Sasaki J, Imazato S.  Investigation of the cytotoxicity of aluminum oxide nanoparticles and nanowires and their localization in L929 fibroblasts and RAW264 macrophages.  J. Biomed. Mater. Res. Part B Appl. Biomater.  2016  104:241-52  PubMed ID: 25715832   DOI: 10.1002/jbm.b.33377
9520  Lu Y, Cao L, Egami Y, Kawai K, Araki N.  Cofilin contributes to phagocytosis of IgG-opsonized particles but not non-opsonized particles in RAW264 macrophages.  Microscopy (Oxf)  2016  65:233-42  PubMed ID: 26754560   DOI: 10.1093/jmicro/dfv376
9550  Takeuchi T, Nagasaka M, Shimizu M, Tamura M, Arata Y.  N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation.  Bone Rep  2016  5:15-21  PubMed ID: 28326343   DOI: 10.1016/j.bonr.2016.02.001
9554  Kuno M, Li G, Moriura Y, Hino Y, Kawawaki J, Sakai H.  Acid-inducible proton influx currents in the plasma membrane of murine osteoclast-like cells.  Pflugers Arch.  2016  468:837-47  PubMed ID: 26843093   DOI: 10.1007/s00424-016-1796-7
9564  Wada T, Sunaga H, Miyata K, Shirasaki H, Uchiyama Y, Shimba S.  Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression.  J. Biol. Chem.  2016  291:7004-16  PubMed ID: 26865635   DOI: 10.1074/jbc.M115.693655
9569  Pengjam Y, Madhyastha H, Madhyastha R, Yamaguchi Y, Nakajima Y, Maruyama M.  NF-κB pathway inhibition by anthrocyclic glycoside aloin is key event in preventing osteoclastogenesis in RAW264.7 cells.  Phytomedicine  2016  23:417-28  PubMed ID: 27002412   DOI: 10.1016/j.phymed.2016.01.006
9573  Maeda Y, Echizen K, Oshima H, Yu L, Sakulsak N, Hirose O, Yamada Y, Taniguchi T, Jenkins BJ, Saya H, Oshima M.  Myeloid Differentiation Factor 88 Signaling in Bone Marrow-Derived Cells Promotes Gastric Tumorigenesis by Generation of Inflammatory Microenvironment.  Cancer Prev Res (Phila)  2016  9:253-63  PubMed ID: 26888865   DOI: 10.1158/1940-6207.CAPR-15-0315
9607  Sugiyama K, Muroi M, Kinoshita M, Hamada O, Minai Y, Sugita-Konishi Y, Kamata Y, Tanamoto K.  NF-κB activation via MyD88-dependent Toll-like receptor signaling is inhibited by trichothecene mycotoxin deoxynivalenol.  J Toxicol Sci  2016  41:273-9  PubMed ID: 26961612   DOI: 10.2131/jts.41.273
9609  Nakabayashi H, Aoyama S, Kawahara M, Nagamune T.  Differentiation signalobody: Demonstration of antigen-dependent osteoclast differentiation from a progenitor cell line.  J. Biosci. Bioeng.  2016  122:357-63  PubMed ID: 26979343   DOI: 10.1016/j.jbiosc.2016.02.010
9612  Furuoka M, Ozaki K, Sadatomi D, Mamiya S, Yonezawa T, Tanimura S, Takeda K.  TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells.  J. Cell. Physiol.  2016  231:2761-7  PubMed ID: 26989816   DOI: 10.1002/jcp.25385
9673  Okahashi N, Nakata M, Kuwata H, Kawabata S.  Streptococcus oralis Induces Lysosomal Impairment of Macrophages via Bacterial Hydrogen Peroxide.  Infect. Immun.  2016  84:2042-2050  PubMed ID: 27113357   DOI: 10.1128/IAI.00134-16
9690  Elfeky M, Kaede R, Okamatsu-Ogura Y, Kimura K.  Adiponectin Inhibits LPS-Induced HMGB1 Release through an AMP Kinase and Heme Oxygenase-1-Dependent Pathway in RAW 264 Macrophage Cells.  Mediators Inflamm.  2016  2016:5701959  PubMed ID: 27313399   DOI: 10.1155/2016/5701959
9692  Kure A, Nakagawa K, Kondo M, Kato S, Kimura F, Watanabe A, Shoji N, Hatanaka S, Tsushida T, Miyazawa T.  Metabolic Fate of Luteolin in Rats: Its Relationship to Anti-inflammatory Effect.  J. Agric. Food Chem.  2016  64:4246-54  PubMed ID: 27170112   DOI: 10.1021/acs.jafc.6b00964
9706  Zhang J, Hiromoto S, Yamazaki T, Niu J, Huang H, Jia G, Li H, Ding W, Yuan G.  Effect of macrophages on in vitro corrosion behavior of magnesium alloy.  J Biomed Mater Res A  2016  104:2476-87  PubMed ID: 27223576   DOI: 10.1002/jbm.a.35788
9740  Sunarso , Toita R, Tsuru K, Ishikawa K.  A superhydrophilic titanium implant functionalized by ozone gas modulates bone marrow cell and macrophage responses.  J Mater Sci Mater Med  2016  27:127  PubMed ID: 27344451   DOI: 10.1007/s10856-016-5741-2
9747  Arikawa M, Kakinuma Y, Noguchi T, Todaka H, Sato T.  Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation.  Eur. J. Pharmacol.  2016  789:17-26  PubMed ID: 27373848   DOI: 10.1016/j.ejphar.2016.06.053
9818  Kanzaki H, Shinohara F, Suzuki M, Wada S, Miyamoto Y, Yamaguchi Y, Katsumata Y, Makihira S, Kawai T, Taubman MA, Nakamura Y.  A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma.  Sci Rep  2016  6:32259  PubMed ID: 27573075   DOI: 10.1038/srep32259
9882  Moriwaki S, Into T, Suzuki K, Miyauchi M, Takata T, Shibayama K, Niida S.  γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.  Sci Rep  2016  6:35930  PubMed ID: 27775020   DOI: 10.1038/srep35930
9922  Yamawaki T, Ito E, Mukai A, Ueno M, Yamada J, Sotozono C, Kinoshita S, Hamuro J.  The Ingenious Interactions Between Macrophages and Functionally Plastic Retinal Pigment Epithelium Cells.  Invest. Ophthalmol. Vis. Sci.  2016  57:5945-5953  PubMed ID: 27820950   DOI: 10.1167/iovs.16-20604
9969  Domon H, Oda M, Maekawa T, Nagai K, Takeda W, Terao Y.  Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis.  Sci Rep  2016  6:38013  PubMed ID: 27892542   DOI: 10.1038/srep38013
10852  Kejuan Li, Xi Yang, Xuansheng Hu, Chao Han, Zhongfang Lei, Zhenya Zhang  In vitro antioxidant, immunomodulatory and anticancer activities of two fractions of aqueous extract from Helicteres angustifolia L. root  Journal of the Taiwan Institute of Chemical Engineers  2016  61:75-82    DOI: 10.1016/j.jtice.2015.12.022
10857    Clinical Evaluation of Novel Natural Polysaccharides Sacran as a Skincare Material for Atopic Dermatitis Patients   Journal of Cosmetics, Dermatological Sciences and Applications  2016  6, 9-18    DOI: 10.4236/jcdsa.2016.61002
10869    Isolation and Biochemical Characterization of Mucus Proteins in Japanese Bunching Onion (Allium fistulosum) Green Leaves  Food Science and Technology Research  2016  22    DOI: 10.3136/fstr.22.235
9409  Nobutaka Sato 1, Jiro Ichikawa 1, Masanori Wako, Tetsuro Ohba, Masanori Saito, Hironao Sato, Kensuke Koyama, Tetsuo Hagino, Jonathan G Schoenecker, Takashi Ando, Hirotaka Haro  Thrombin Induced by the Extrinsic Pathway and PAR-1 Regulated Inflammation at the Site of Fracture Repair  Bone  2016  83:23-34  PubMed ID: 26475502   DOI: 10.1016/j.bone.2015.10.005
10109  Yusuke Kono, Ayu Iwasaki, Kenta Matsuoka, Takuya Fujita  Effect of Mechanical Agitation on Cationic Liposome Transport Across an Unstirred Water Layer in Caco-2 Cells  Biol Pharm Bull   2016  39(8):1293-9  PubMed ID: 27476939   DOI: 10.1248/bpb.b16-00050
12622  Goto T, Naknukool S, Yoshitake R, Hanafusa Y, Tokiwa S, Li Y, Sakamoto T, Nitta T, Kim M, Takahashi N, Yu R, Daiyasu H, Seno S, Matsuda H, Kawada T.  Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes  Cytokinec  2016  77:107-14  PubMed ID: 26556104   DOI: 10.1016/j.cyto.2015.11.001
12858  Hashimoto M, Kawai K, Kawakami H, Imazato S.  Matrix metalloproteases inhibition and biocompatibility of gold and platinum nanoparticles  J Biomed Mater Res A  2016  104(1):209-17.  PubMed ID: 26282184   DOI: 10.1002/jbm.a.35557
12885  Ichikawa N, Yamashita K, Funakoshi T, Ichihara S, Fukai M, Ogura M, Kobayashi N, Zaitsu M, Yoshida T, Shibasaki S, Koshizuka Y, Tsunetoshi Y, Sato M, Einama T, Ozaki M, Umezawa K, Suzuki T, Todo S.  Novel anti-inflammatory agent 3-[(dodecylthiocarbonyl)-methyl]-glutarimide ameliorates murine models of inflammatory bowel disease  Inflamm Res  2016  65(3):245-60  PubMed ID: 26683259   DOI: 10.1007/s00011-015-0911-0
12936  Hayashida Y, Ikeda Y, Sawada K, Kawai K, Kato T, Kakehi Y, Araki N.  Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor  Int J Cancer  2016  139(3):700-11  PubMed ID: 26989815   DOI: 10.1002/ijc.30097
12956  Nagahara H, Yamamoto A, Seno T, Obayashi H, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y.  Allograft inflammatory factor-1 in the pathogenesis of bleomycin-induced acute lung injury  Biosci Trends  2016  10(1):47-53.  PubMed ID: 26911661   DOI: 10.5582/bst.2016.01027
13985  Nakayama M, Nakamura A, Hondou T, Miyata H.  Evaluation of cell viability, DNA single-strand breaks, and nitric oxide production in LPS-stimulated macrophage RAW264 exposed to a 50-Hz magnetic field  Int J Radiat Biol  2016  ;92(10):583-9  PubMed ID: 27430265   DOI: 10.1080/09553002.2016.1206224
14099  Yamamoto S, Ohta N, Matsumoto A, Horiguchi Y, Koide M, Fujino Y.  Haloperidol Suppresses NF-kappaB to Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Response in RAW 264 Cells  Med Sci Monit  2016  22:367-72  PubMed ID: 26842661   DOI: 10.12659/msm.895739
14110  Taki M, Tagami T, Fukushige K, Ozeki T.  Fabrication of nanocomposite particles using a two-solution mixing-type spray nozzle for use in an inhaled curcumin formulation  Int J Pharm  2016  511(1):104-110  PubMed ID: 27374204   DOI: 10.1016/j.ijpharm.2016.06.134
14164  Yiting Li, Shili Meng, Min Shi, Xuansheng Hu, Yingnan Yang, Zhenya Zhang  Bioactivity Evaluation of Crude Polysaccharide from Rice Bran Fermented by Preussia Aemulans and the Changes in its Nutritional Contents  Journal of Food Biochemistry  2016  40:664-672    DOI: 10.1111/jfbc.12258
14578  Ito S, Tanaka Y, Oshino R, Okado S, Hori M, Isobe KI.  GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation  Cell Death Dis  2016  7(5):e2219  PubMed ID: 27171261   DOI: 10.1038/cddis.2016.116
15302  Yuichi Masuda, Chitose Maruyama, Kyuichi Kawabata, Yoshimitsu Hamano, Takayuki Doi  Synthesis of (2S,3R,4R)-3,4-dihydroxyarginine and its inhibitory activity against nitric oxide synthase  Tetrahedron  2016  72:5602-5611    DOI: 10.1016/j.tet.2016.07.050
7085  Hosokawa T, Tsuchiya Y, Okubo N, Kunimoto T, Minami Y, Fujiwara H, Umemura Y, Koike N, Kubo T, Yagita K.  Robust Circadian Rhythm and Parathyroid Hormone-Induced Resetting during Hypertrophic Differentiation in ATDC5 Chondroprogenitor Cells.  Acta Histochem Cytochem  2015  48:165-71  PubMed ID: 26855448   DOI: 10.1267/ahc.15025
7137  Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa TO, Kataoka Y, Yamamura K.  Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo.  Sci Rep  2015  5:17205  PubMed ID: 26598133   DOI: 10.1038/srep17205
7142  Washio K, Kobayashi M, Saito N, Amagasa M, Kitamura H.  Propolis Ethanol Extract Stimulates Cytokine and Chemokine Production through NF-κB Activation in C2C12 Myoblasts.  Evid Based Complement Alternat Med  2015  2015:349751  PubMed ID: 26604971   DOI: 10.1155/2015/349751
7221  Sawada Y, Sakamoto Y, Toh M, Ohara N, Hatanaka Y, Naka A, Kishimoto Y, Kondo K, Iida K.  Milk-derived peptide Val-Pro-Pro (VPP) inhibits obesity-induced adipose inflammation via an angiotensin-converting enzyme (ACE) dependent cascade.  Mol Nutr Food Res  2015  59:2502-10  PubMed ID: 26346532   DOI: 10.1002/mnfr.201500324
7229  Inoue K, Imai Y.  Fatostatin, an SREBP inhibitor, prevented RANKL-induced bone loss by suppression of osteoclast differentiation.  Biochim. Biophys. Acta  2015  1852:2432-41  PubMed ID: 26319416   DOI: 10.1016/j.bbadis.2015.08.018
7274  Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.  IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.  J. Clin. Invest.  2015  125:3269-79  PubMed ID: 26193638   DOI: 10.1172/JCI76765
7293  Tang L, Okamoto S, Shiuchi T, Toda C, Takagi K, Sato T, Saito K, Yokota S, Minokoshi Y.  Sympathetic Nerve Activity Maintains an Anti-Inflammatory State in Adipose Tissue in Male Mice by Inhibiting TNF-α Gene Expression in Macrophages.  Endocrinology  2015  156:3680-94  PubMed ID: 26132918   DOI: 10.1210/EN.2015-1096
7321  Hashimoto M, Sasaki JI, Yamaguchi S, Kawai K, Kawakami H, Iwasaki Y, Imazato S.  Gold Nanoparticles Inhibit Matrix Metalloproteases without Cytotoxicity.  J. Dent. Res.  2015  94:1085-91  PubMed ID: 26040283   DOI: 10.1177/0022034515589282
7340  Suzuki N, Takimoto K, Kawashima N.  Cathepsin K Inhibitor Regulates Inflammation and Bone Destruction in Experimentally Induced Rat Periapical Lesions.  J Endod  2015  41:1474-9  PubMed ID: 25990199   DOI: 10.1016/j.joen.2015.04.013
7420  Miyazaki T, Miyauchi S, Anada T, Tawada A, Suzuki O.  Chondroitin Sulfate-E Binds to Both Osteoactivin and Integrin αVβ3 and Inhibits Osteoclast Differentiation.  J. Cell. Biochem.  2015  116:2247-57  PubMed ID: 25820496   DOI: 10.1002/jcb.25175
7448  Takeuchi T, Shimakawa G, Tamura M, Yokosawa H, Arata Y.  ISG15 regulates RANKL-induced osteoclastogenic differentiation of RAW264 cells.  Biol. Pharm. Bull.  2015  38:482-6  PubMed ID: 25757932   DOI: 10.1248/bpb.b14-00410
7451  Hashimoto M, Imazato S.  Cytotoxic and genotoxic characterization of aluminum and silicon oxide nanoparticles in macrophages.  Dent Mater  2015  31:556-64  PubMed ID: 25749564   DOI: 10.1016/
7467  Kawabata K, Kato Y, Sakano T, Baba N, Hagiwara K, Tamura A, Baba S, Natsume M, Ohigashi H.  Effects of phytochemicals on in vitro anti-inflammatory activity of Bifidobacterium adolescentis.  Biosci. Biotechnol. Biochem.  2015  79:799-807  PubMed ID: 25721815   DOI: 10.1080/09168451.2015.1006566
7492  Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M.  Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury.  Am. J. Physiol. Renal Physiol.  2015  308:F878-87  PubMed ID: 25656369   DOI: 10.1152/ajprenal.00590.2014
7501  Lai YT, Sato M, Ohta S, Akamatsu K, Nakao S, Sakai Y, Ito T.  Preparation of uniform-sized hemoglobin-albumin microspheres as oxygen carriers by Shirasu porous glass membrane emulsification technique.  Colloids Surf B Biointerfaces  2015  127:1-7  PubMed ID: 25635614   DOI: 10.1016/j.colsurfb.2015.01.018
7505  Kim YI, Mohri S, Hirai S, Lin S, Goto T, Ohyane C, Sakamoto T, Takahashi H, Shibata D, Takahashi N, Kawada T.  Tomato extract suppresses the production of proinflammatory mediators induced by interaction between adipocytes and macrophages.  Biosci. Biotechnol. Biochem.  2015  79:82-7  PubMed ID: 25603813   DOI: 10.1080/09168451.2014.962472
7517  Taniguchi M, Ochiai A, Takahashi K, Nakamichi S, Nomoto T, Saitoh E, Kato T, Tanaka T.  Antimicrobial activity and mechanism of action of a novel cationic α-helical octadecapeptide derived from α-amylase of rice.  Biopolymers  2015  104:73-83  PubMed ID: 25581614   DOI: 10.1002/bip.22605
7526  F Shima, T Akagi, M Shudo, E Mochizuki, T Tsuda, S Kuwabata M Akashi  Interaction between living cells and polymeric particles: potential application of ionic liquid for evaluating the cellular uptake of biodegradable polymeric particles composed of poly(amino acid).  Polymer Journal  2015  47:631-638    DOI: 10.1038/pj.2015.40
6343  Uto T, Tung NH, Taniyama R, Miyanowaki T, Morinaga O, Shoyama Y.  Anti-inflammatory Activity of Constituents Isolated from Aerial Part of Angelica acutiloba Kitagawa.  Phytother Res  2015  29(12):1956-63  PubMed ID: 26463105   DOI: 10.1002/ptr.5490
6621  Koyama T, Kamemura K.  Global increase in O-linked N-acetylglucosamine modification promotes osteoblast differentiation.  Exp Cell Res  2015  338(2):194-202  PubMed ID: 26302267   DOI: 10.1016/j.yexcr.2015.08.009
9365  Akio Watanabe, Momochika Kumagai, Takashi Mishima, Junya Ito, Yurika Otoki, Teppei Harada, Tsuyoshi Kato, Mikihiko Yoshida, Misora Suzuki, Izumi Yoshida, Kazuhiro Fujita, Masatoshi Watai, Kiyotaka Nakagawa, Teruo Miyazawa  Toddaculin, Isolated From of Toddalia Asiatica (L.) Lam., Inhibited Osteoclastogenesis in RAW 264 Cells and Enhanced Osteoblastogenesis in MC3T3-E1 Cells  PLoS One  2015  10(5):e0127158  PubMed ID: 25993011   DOI: 10.1371/journal.pone.0127158
9378  R Toita, Sunarso, A N Rashid, K Tsuru, K Ishikawa  Modulation of the Osteoconductive Property and Immune Response of Poly(ether Ether Ketone) by Modification With Calcium Ions  J Mater Chem B  2015  3(44):8738-8746  PubMed ID: 32262731   DOI: 10.1039/c5tb01679g
10173  Yao-Tong Lai, Seiichi Ohta, Kazuki Akamatsu, Shin-Ichi Nakao, Yasuyuki Sakai, Taichi Ito  Size-dependent Interaction of Cells and Hemoglobin-Albumin Based Oxygen Carriers Prepared Using the SPG Membrane Emulsification Technique  Biotechnol Prog .   2015  31(6):1676-84  PubMed ID: 26399378   DOI: 10.1002/btpr.2170
10195  Akihiko Nagao, Takashi Maoka, Hiroshi Ono, Eiichi Kotake-Nara, Miyuki Kobayashi, Mie Tomita  A 3-hydroxy β-End Group in Xanthophylls Is Preferentially Oxidized to a 3-oxo ε-End Group in Mammals  J Lipid Res  2015  56(2):449-62  PubMed ID: 25502844   DOI: 10.1194/jlr.P055459
12234  Masayori Hagimori, Naoko Mizuyama, Yoshinori Tominaga, Takahiro Mukai,Hideo Saji  A low-molecular-weight fluorescent sensor with Zn2+ dependent bathochromic shift of emission wavelength and its imaging in living cells  Dyes and Pigments  2015  113:205-209    DOI: 10.1016/j.dyepig.2014.07.032
12237  Shiro Kato, Yuki Masuda, Morichika Konishi, Tadao Oikawa  Enantioselective analysis of D- and L-amino acids from mouse macrophages using high performance liquid chromatography  J Pharm Biomed Anal  2015  116:101-4  PubMed ID: 25982753   DOI: 10.1016/j.jpba.2015.04.028
12245  Takashi Ando, Takayuki Komatsu, Yoshikazu Naiki, Takashi Yokochi, Daisuke Watanabe, Naoki Koide  Pretreatment of LPS inhibits IFN-β-induced STAT1 phosphorylation through SOCS3 induced by LPS  Biomed Pharmacother  2015  76:1-5  PubMed ID: 26653542   DOI: 10.1016/j.biopha.2015.10.019
12252  Yoshiro Kato, Hideki Kamiya, Naoki Koide, Erdenezaya Odkhuu, Takayuki Komatsu, Atsuko Watarai, Masaki Kondo, Koichi Kato, Jiro Nakamura, Takashi Yokochi  Irbesartan attenuates production of high-mobility group box 1 in response to lipopolysaccharide via downregulation of interferon-β production  Int Immunopharmacol  2015  26(1):97-102  PubMed ID: 25817178   DOI: 10.1016/j.intimp.2015.03.015
12259  Shusong Wu, Xi He, Xiaosong Wu, Si Qin, Jianhua He, Shirui Zhang, De-Xing Hou  Inhibitory effects of blue honeysuckle (Lonicera caerulea L) on adjuvant-induced arthritis in rats: Crosstalk of anti-inflammatory and antioxidant effects  J Functional Foods  2015  17:514-515    DOI: 10.1016/j.jff.2015.06.007
13961  Fujioka K, Kishida T, Ejima A, Yamamoto K, Fujii W, Murakami K, Seno T, Yamamoto A, Kohno M, Oda R, Yamamoto T, Fujiwara H, Kawahito Y, Mazda O.  Inhibition of osteoclastogenesis by osteoblast-like cells genetically engineered to produce interleukin-10  Biochem Biophys Res Commun  2015  456(3):785-91  PubMed ID: 25514036   DOI: 10.1016/j.bbrc.2014.12.040
14465  Okinaga T, Ariyoshi W, Nishihara T.  Aggregatibacter actinomycetemcomitans Invasion Induces Interleukin-1β Production Through Reactive Oxygen Species and Cathepsin B  J Interferon Cytokine Res  2015  35(6):431-40  PubMed ID: 25789553   DOI: 10.1089/jir.2014.0127
14969  Kiyomiya H, Ariyoshi W, Okinaga T, Kaneuji T, Mitsugi S, Sakurai T, Habu M, Yoshioka I, Tominaga K, Nishihara T.  IL-33 inhibits RANKL-induced osteoclast formation through the regulation of Blimp-1 and IRF-8 expression  Biochem Biophys Res Commun  2015  460(2):320-6  PubMed ID: 25795135   DOI: 10.1016/j.bbrc.2015.03.033
14983  He YM, Zhu S, Ge YW, Kazuma K, Zou K, Cai SQ, Komatsu K.  The anti-inflammatory secoiridoid glycosides from gentianae scabrae radix: the root and rhizome of Gentiana scabra  J Nat Med  2015  69(3):303-12  PubMed ID: 25750086   DOI: 10.1007/s11418-015-0894-8
14991  Komiya M, Fujii G, Miyamoto S, Takahashi M, Ishigamori R, Onuma W, Ishino K, Totsuka Y, Fujimoto K, Mutoh M.  Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK-A(y) and Apc mutant Min mice  Cancer Sci  2015  106(11):1499-505  PubMed ID: 26310859   DOI: 10.1111/cas.12801
15020  Mori K, Ouchi K, Hirasawa N.  The Anti-Inflammatory Effects of Lion's Mane Culinary-Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) in a Coculture System of 3T3-L1 Adipocytes and RAW264 Macrophages  Int J Med Mushrooms  2015  17(7):609-18  PubMed ID: 26559695   DOI: 10.1615/intjmedmushrooms.v17.i7.10
15021  Tan H, Ashour A, Katakura Y, Shimizu K.  A structure-activity relationship study on antiosteoclastogenesis effect of triterpenoids from the leaves of loquat (Eriobotrya japonica)  Phytomedicine  2015  22(4):498-503  PubMed ID: 25925972   DOI: 10.1016/j.phymed.2015.03.002
15028  Inaba H, Yoshigai E, Okuyama T, Murakoshi M, Sugiyama K, Nishino H, Nishizawa M.  Antipyretic analgesic drugs have different mechanisms for regulation of the expression of inducible nitric oxide synthase in hepatocytes and macrophages  Nitric Oxide  2015  44:61-70  PubMed ID: 25499030   DOI: 10.1016/j.niox.2014.12.001
15148  Kojima C, Kameyama R, Yamada M, Ichikawa M, Waku T, Handa A, Tanaka N.  Ovalbumin Delivery by Guanidine-Terminated Dendrimers Bearing an Amyloid-Promoting Peptide via Nanoparticle Formulation  Bioconjug Chem  2015  26(8):1804-10  PubMed ID: 26186179   DOI: 10.1021/acs.bioconjchem.5b00325
13891  Nakamura R, Kayamori K, Oue E, Sakamoto K, Harada K, Yamaguchi A.  Transforming growth factor-β synthesized by stromal cells and cancer cells participates in bone resorption induced by oral squamous cell carcinoma  Biochem Biophys Res Commun  2015  458(4):777-82  PubMed ID: 25681764   DOI: 10.1016/j.bbrc.2015.02.013
15208  Wang Q, Yokoo H, Takashina M, Sakata K, Ohashi W, Abedelzaher LA, Imaizumi T, Sakamoto T, Hattori K, Matsuda N, Hattori Y.  Anti-Inflammatory Profile of Levosimendan in Cecal Ligation-Induced Septic Mice and in Lipopolysaccharide-Stimulated Macrophages  Crit Care Med  2015  43(11):e508-20  PubMed ID: 26468714   DOI: 10.1097/CCM.0000000000001269
15255  Asakawa S, Kishimoto Y, Takano T, Okita K, Takakuwa S, Sato T, Hiratsuka M, Takeuchi O, Hirasawa N.  Nickel ions selectively inhibit lipopolysaccharide-induced interleukin-6 production by decreasing its mRNA stability  PLoS One  2015  10(3):e0119428  PubMed ID: 25742007   DOI: 10.1371/journal.pone.0119428
15444  Oka H, Kitagawa M, Takata T.  F-spondin inhibits differentiation of clastic precursors via lipoprotein receptor-related protein 8 (LRP8)  J Periodontol  2015  86(3):465-72  PubMed ID: 25299387   DOI: 10.1902/jop.2014.140419
15446  Nomura H, Takanashi S, Tanaka M, Haniu H, Aoki K, Okamoto M, Kobayashi S, Takizawa T, Usui Y, Oishi A, Kato H, Saito N.  Specific biological responses of the synovial membrane to carbon nanotubes  Sci Rep  2015  5:14314  PubMed ID: 26388047   DOI: 10.1038/srep14314
15305  Oh-Hashi K, Sone A, Hikiji T, Hirata Y, Vitiello M, Fedele M, Ishigaki S, Sobue G, Kiuchi K.  Transcriptional and post-transcriptional regulation of transmembrane protein 132A  Mol Cell Biochem  2015  405(1-2):291-9  PubMed ID: 25926156   DOI: 10.1007/s11010-015-2419-x
15479  Ito S, Tanaka Y, Oshino R, Aiba K, Thanasegaran S, Nishio N, Isobe K.  GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy  Sci Rep  2015  5:8327  PubMed ID: 25659802   DOI: 10.1038/srep08327
15103  Cuilian Tao, Yufang Zhu, Xianglan Li, Nobutaka Hanagata  Binding of CpG oligodeoxynucleotides to mesoporous silica nanoparticles for enhancing delivery efficiency  Microporous and Mesoporous Materials  2015  204:91-98    DOI: 10.1016/j.micromeso.2014.11.007
16692  Shimada H, Nakamura Y, Nakanishi T, Tamai I.  OATP2A1/SLCO2A1-mediated prostaglandin E2 loading into intracellular acidic compartments of macrophages contributes to exocytotic secretion  Biochem Pharmacol  2015  98(4):629-38  PubMed ID: 26474801   DOI: 10.1016/j.bcp.2015.10.009
17440  Tahara Y, Yasuoka J, Sawada S, Sasaki Y, Akiyoshi K.  Effective CpG DNA delivery using amphiphilic cycloamylose nanogels  Biomater Sci  2015  3(2):256-64  PubMed ID: 26218116   DOI: 10.1039/c4bm00293h
17452  Odkhuu E, Mendjargal A, Koide N, Naiki Y, Komatsu T, Yokochi T.  Lipopolysaccharide downregulates the expression of p53 through activation of MDM2 and enhances activation of nuclear factor-kappa B  Immunobiology  2015  220(1):136-41  PubMed ID: 25172547   DOI: 10.1016/j.imbio.2014.08.010
17457  Odkhuu E, Koide N, Tsolmongyn B, Jambalganiin U, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Involvement of redox balance in in vitro osteoclast formation of RAW 264.7 macrophage cells in response to LPS  Innate Immun  2015  21(2):194-202  PubMed ID: 24595208   DOI: 10.1177/1753425914524242
17458  Shoji T, Higuchi H, Zaitsu Y, Nishijima K, Iijima S.  Enhanced lentiviral vector production in 293FT cells expressing Siglec-9  Cytotechnology  2015  67(4):593-600  PubMed ID: 24464124   DOI: 10.1007/s10616-013-9679-7
17459  Ando M, Shoji T, Tu W, Higuchi H, Nishijima K, Iijima S.  Lectin-dependent localization of cell surface sialic acid-binding lectin Siglec-9  Cytotechnology  2015  67(4):601-8  PubMed ID: 24449467   DOI: 10.1007/s10616-014-9691-6
18289  Jambalganiin U, Tsolmongyn B, Koide N, Odkhuu E, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  A novel mechanism for inhibition of lipopolysaccharide-induced proinflammatory cytokine production by valproic acid  Int Immunopharmacol  2014  20(1):181-7  PubMed ID: 24631367   DOI: 10.1016/j.intimp.2014.02.032
6334  Itoh T, Tsuchida A, Muramatsu Y, Ninomiya M, Ando M, Tsukamasa Y, Koketsu M.  Antimicrobial and anti-inflammatory properties of nostocionone isolated from Nostoc commune Vauch and its derivatives against Propionibacterium acnes.  Anaerobe  2014  27:56-63  PubMed ID: 24699048   DOI: 10.1016/j.anaerobe.2014.03.006
2777  Yamasaki T, Ariyoshi W, Okinaga T, Adachi Y, Hosokawa R, Mochizuki S, Sakurai K, Nishihara T.  The dectin 1 agonist curdlan regulates osteoclastogenesis by inhibiting nuclear factor of activated T cells cytoplasmic 1 (NFATc1) through Syk kinase.  J Biol Chem  2014  289(27):19191-203  PubMed ID: 24821724   DOI: 10.1074/jbc.M114.551416
6607  Nakazato R, Takarada T, Watanabe T, Nguyen BT, Ikeno S, Hinoi E, Yoneda Y.  Constitutive and functional expression of runt-related transcription factor-2 by microglial cells.  Neurochem Int  2014  74:24-35  PubMed ID: 24768841   DOI: 10.1016/j.neuint.2014.04.010
9114  Erdenezaya Odkhuu, Takayuki Komatsu, Yoshikazu Naiki, Naoki Koide, Takashi Yokochi  Sendai Virus C Protein Inhibits Lipopolysaccharide-Induced Nitric Oxide Production Through Impairing Interferon-β Signaling  Int Immunopharmacol  2014  23 (1), 267-72  PubMed ID: 25242386   DOI: 10.1016/j.intimp.2014.09.012
9323  Ran Zhao, Masayoshi Kamon, Kazuichi Sakamoto  (–)-Epigallocatechingallate Interferes RANKL/RANK Signal Pathway and Induces Apoptosis during Osteoclastogenesis in RAW264 Cell  Food and Nutrition Sciences  2014  5:107-116    DOI: 10.4236/fns.2014.52014
9348  W Ariyoshi, T Okinaga, C B Knudson, W Knudson, T Nishihara  High Molecular Weight Hyaluronic Acid Regulates Osteoclast Formation by Inhibiting Receptor Activator of NF-κB Ligand Through Rho Kinase  Osteoarthritis Cartilage  2014  22(1):111-20  PubMed ID: 24185105   DOI: 10.1016/j.joca.2013.10.013
9349  Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo  Responses of RAW264.7 Macrophages to Water-Dispersible Gold and Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds  J Biomed Mater Res A  2014  102(6):1838-49  PubMed ID: 23784947   DOI: 10.1002/jbm.a.34854
9351  Miki Tadaishi, Yoriko Nishide, Yuko Tousen, Marlena C Kruger, Yoshiko Ishimi  Cooperative Effects of Soy Isoflavones and Carotenoids on Osteoclast Formation  J Clin Biochem Nutr  2014  54(2):109-15  PubMed ID: 24688220   DOI: 10.3164/jcbn.13-94
12850  Tada R, Koide Y, Yamamuro M, Tanaka R, Hidaka A, Nagao K, Aramaki Y.  Maleylated-BSA suppresses lipopolysaccharide-induced IL-6 production by activating the ERK-signaling pathway in murine RAW264.7 cells  Int Immunopharmacol  2014  19(1):5-9  PubMed ID: 24406428   DOI: 10.1016/j.intimp.2013.12.027
13737  Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Masahiro Iijima, Kazuhiko Endo  Evaluation of Silver Nanoparticle Toxicity to RAW264.7 Cells in a Three-Dimensional Cell Culture  Journal of Biomaterials and Tissue Engineering  2014  4:51-58    DOI: 10.1166/jbt.2014.1141
15027  Dan Zhu, Hongyi Sun, Shuhong Li, Xuansheng Hu, Xi Yuan, Chao Han, Zhenya Zhang  Influence of Drying Methods on Antioxidant Activities and Immunomodulatory of Aqueous Extract From Soybean Curd Residue Fermentated by Grifola frondosa  International Journal of Biology  2014  7:82-92    DOI: 10.5539/ijb.v7n1p82
15306  Itoh T, Koketsu M, Yokota N, Touho S, Ando M, Tsukamasa Y.  Reduced scytonemin isolated from Nostoc commune suppresses LPS/IFNγ-induced NO production in murine macrophage RAW264 cells by inducing hemeoxygenase-1 expression via the Nrf2/ARE pathway  Food Chem Toxicol  2014  ;69:330-8  PubMed ID: 24795232   DOI: 10.1016/j.fct.2014.04.019
15307  Daisuke Yamanaka, Katsuya Tajima, Yoshiyuki Adachi, Ken-ichi Ishibashi, Noriko N. Miura, Masuro Motoi, Naohito Ohno  Effect of polymeric caffeic acid on antitumour activity and natural killer cell activity in mice  Journal of Functional Foods  2014  6:513-522    DOI: 10.1016/j.jff.2013.11.018
15308  Hayashi Y, Kuroda T, Kishimoto H, Wang C, Iwama A, Kimura K.  Downregulation of rRNA transcription triggers cell differentiation  PLoS One  2014  9(5):e98586  PubMed ID: 24879416   DOI: 10.1371/journal.pone.0098586
15309  Kusunoki H, Taniyama Y, Otsu R, Rakugi H, Morishita R.  Anti-inflammatory effects of hepatocyte growth factor on the vicious cycle of macrophages and adipocytes  Hypertens Res  2014  37(6):500-6  PubMed ID: 24621470   DOI: 10.1038/hr.2014.41
15310  Sato S, Sakurai T, Ogasawara J, Shirato K, Ishibashi Y, Oh-ishi S, Imaizumi K, Haga S, Hitomi Y, Izawa T, Ohira Y, Ohno H, Kizaki T.  Direct and indirect suppression of interleukin-6 gene expression in murine macrophages by nuclear orphan receptor REV-ERBα  ScientificWorldJournal  2014  2014:685854  PubMed ID: 25401152   DOI: 10.1155/2014/685854
15311  Araki N, Ikeda Y, Kato T, Kawai K, Egami Y, Miyake K, Tsurumaki N, Yamaguchi M.  Development of an automated fluorescence microscopy system for photomanipulation of genetically encoded photoactivatable proteins (optogenetics) in live cells  Microscopy (Oxf)  2014  63(3):255-60  PubMed ID: 24523516   DOI: 10.1093/jmicro/dfu003
15312  Sato Y, Hara H, Okuno T, Ozaki N, Suzuki S, Yokomizo T, Kaisho T, Yoshida H.  IL-27 affects helper T cell responses via regulation of PGE2 production by macrophages  Biochem Biophys Res Commun  2014  451(2):215-21  PubMed ID: 25088998   DOI: 10.1016/j.bbrc.2014.07.096
15313  Seiji GODA, Hiroshi HAYASHI, Yosuke UJII, Osamu TAKEUCHI, Reiko KOMASA, Eisuke DOMAE, Kazuyo YAMAMOTO, Naoyuki MATSUMOTO, Takashi IKEO  Fibronectin inhibited RANKL-induced differentiation into osteoclast  Journal of Oral Tissue Engineering  2014  11:227-233    DOI: 10.11223/jarde.11.227
15314  Sarntivijai S, Lin Y, Xiang Z, Meehan TF, Diehl AD, Vempati UD, Schürer SC, Pang C, Malone J, Parkinson H, Liu Y, Takatsuki T, Saijo K, Masuya H, Nakamura Y, Brush MH, Haendel MA, Zheng J, Stoeckert CJ, Peters B, Mungall CJ, Carey TE, States DJ, Athey BD, He Y.  CLO: The cell line ontology  J Biomed Semantics  2014  5:37  PubMed ID: 25852852   DOI: 10.1186/2041-1480-5-37
15315  Suk Hyun Choi, Dong-Seok Kim, Nobuyuki Kozukue, Hyun-Jeong Kim, Yosuke Nishitani, Masashi Mizuno, Carol E. Levin, Mendel Friedman  Protein, free amino acid, phenolic, β-carotene, and lycopene content, and antioxidative and cancer cell inhibitory effects of 12 greenhouse-grown commercial cherry tomato varieties  Journal of Food Composition and Analysis  2014  34:115-127    DOI: 10.1016/j.jfca.2014.03.005
15316  Xu Y, Ito T, Fushimi S, Takahashi S, Itakura J, Kimura R, Sato M, Mino M, Yoshimura A, Matsukawa A.  Spred-2 deficiency exacerbates lipopolysaccharide-induced acute lung inflammation in mice  PLoS One  2014  9(9):e108914  PubMed ID: 25275324   DOI: 10.1371/journal.pone.0108914
15317  Uehara K, Takahashi A, Watanabe M, Nomura Y.  Shark protein improves bone mineral density in ovariectomized rats and inhibits osteoclast differentiation  Nutrition  2014  30(6):719-25  PubMed ID: 24800672   DOI: 10.1016/j.nut.2013.11.005
15319  Ueno-Shuto K, Kato K, Tasaki Y, Sato M, Sato K, Uchida Y, Sakai H, Ono T, Suico MA, Mitsutake K, Tokutomi N, Kai H, Shuto T.  Lipopolysaccharide decreases single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR) expression by suppressing specificity protein 1 (Sp1) via the Toll-like receptor 4 (TLR4)-p38 pathway in monocytes and neutrophils  J Biol Chem  2014  289(26):18097-109  PubMed ID: 24821721   DOI: 10.1074/jbc.M113.532093
15320  Phyu Phyu Khine Zar, Akiko Morishita, Fumio Hashimoto, Kozue Sakao, Makoto Fujii, Koji Wada, De-Xing Hou  Anti-inflammatory effects and molecular mechanisms of loquat (Eriobotrya japonica) tea  Journal of Functional Foods  2014  6:523-533    DOI: 10.1016/j.jff.2013.11.019
15322  Inoue M, Tanabe H, Nakashima K, Ishida Y, Kotani H.  Rexinoids isolated from Sophora tonkinensis with a gene expression profile distinct from the synthetic rexinoid bexarotene  J Nat Prod  2014  77(7):1670-7  PubMed ID: 24959987   DOI: 10.1021/np5002016
15323  Kato Y, Kamiya H, Koide N, Odkhuu E, Komatsu T, Dagvadorj J, Watarai A, Kondo M, Kato K, Nakamura J, Yokochi T.  Spironolactone inhibits production of proinflammatory mediators in response to lipopolysaccharide via inactivation of nuclear factor-κB  Immunopharmacol Immunotoxicol  2014  36(3):237-41  PubMed ID: 24852317   DOI: 10.3109/08923973.2014.921690
7584  T. Atsumi, A. Iwashita, I. Ohtsuka, N. Kakiuchi, Y. Sasaki, M. Mikage, K. Toriizuka  Effects of Atractylodis Lanceae Rhizoma on inflammatory mediator production from the RAW264 macrophage cell line  J Traditional Medicines  2013  30:124-131    DOI: 10.11339/jtm.30.124
18842  Mendjargal A, Odkhuu E, Koide N, Nagata H, Kurokawa T, Nonami T, Yokochi T.  Pifithrin-α, a pharmacological inhibitor of p53, downregulates lipopolysaccharide-induced nitric oxide production via impairment of the MyD88-independent pathway  Int Immunopharmacol  2013  15(4):671-8  PubMed ID: 23454130   DOI: 10.1016/j.intimp.2013.02.014
5424  Takeshi KAWAHARA, Daichi NAKAYAMA, Keisuke TODA, Shyuichiro INAGAKI, Katsumi TANAKA, Hisako YASUI  Suppressive Effect of Wild Saccharomyces cerevisiae and Saccharomyces paradoxus Strains on Ige Production by Mouse Spleen Cells  Food Sci. Technol. Res  2013  19 (6), 1019 – 1027    DOI: 10.3136/fstr.19.1019
6086  Ito S, Tanaka Y, Nishio N, Thanasegaran S, Isobe K.  Establishment of self-renewable GM-CSF-dependent immature macrophages in vitro from murine bone marrow.  PLoS One  2013  8(10):e76943  PubMed ID: 24124601   DOI: 10.1371/journal.pone.0076943
6326  Horibe K, Nakamichi Y, Uehara S, Nakamura M, Koide M, Kobayashi Y, Takahashi N, Udagawa N.  Roles of cathelicidin-related antimicrobial peptide in murine osteoclastogenesis.  Immunology  2013  140(3):344-51  PubMed ID: 23826736   DOI: 10.1111/imm.12146
6466  Etoh T, Kim YP, Ohsaki A, Komiyama K, Hayashi M.  Inhibitory effect of erythraline on Toll-like receptor signaling pathway in RAW264.7 cells.  Biol Pharm Bull  2013  36(8):1363-9  PubMed ID: 23902980   DOI: 10.1248/bpb.b12-00910
6467  Etoh T, Kim YP, Tanaka H, Hayashi M.  Anti-inflammatory effect of berkeleyacetal C through the inhibition of interleukin-1 receptor-associated kinase-4 activity.  Eur J Pharmacol  2013  698(1-3):435-43  PubMed ID: 23127497   DOI: 10.1016/j.ejphar.2012.10.038
9096  Kyoko Ueda, Ryoko Kawabata, Takashi Irie, Yoshiaki Nakai, Yukinobu Tohya, Takemasa Sakaguchi  Inactivation of Pathogenic Viruses by Plant-Derived Tannins: Strong Effects of Extracts From Persimmon (Diospyros Kaki) on a Broad Range of Viruses  PLoS One  2013  8 (1), e55343  PubMed ID: 23372851   DOI: 10.1371/journal.pone.0055343
9100  Hiroki Ishikawa, Naoki Awano, Toshie Fukui, Hiraku Sasaki, Shigeru Kyuwa  The Protective Effects of Lactoferrin Against Murine Norovirus Infection Through Inhibition of Both Viral Attachment and Replication  Biochem Biophys Res Commun  2013  434 (4), 791-6  PubMed ID: 23603257   DOI: 10.1016/j.bbrc.2013.04.013
9169  Akari Ishisaka, Kyuichi Kawabata, Satomi Miki, Yuko Shiba, Shoko Minekawa, Tomomi Nishikawa, Rie Mukai, Junji Terao, Yoshichika Kawai  Mitochondrial Dysfunction Leads to Deconjugation of Quercetin Glucuronides in Inflammatory Macrophages  PLoS One  2013  8 (11), e80843  PubMed ID: 24260490   DOI: 10.1371/journal.pone.0080843
9256  Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo  Micromorphological Cellular Responses of MC3T3-E1 and RAW264.7 After Exposure to Water-Dispersible Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds  Dent Mater J  2013  32(5):725-33  PubMed ID: 24088827   DOI: 10.4012/dmj.2012-203
9359  Yuriko Furuya, Atsushi Inagaki, Masud Khan, Kaoru Mori, Josef M Penninger, Midori Nakamura, Nobuyuki Udagawa, Kazuhiro Aoki, Keiichi Ohya, Kohji Uchida, Hisataka Yasuda  Stimulation of Bone Formation in Cortical Bone of Mice Treated With a Receptor Activator of Nuclear factor-κB Ligand (RANKL)-binding Peptide That Possesses Osteoclastogenesis Inhibitory Activity  J Biol Chem  2013  288(8):5562-71  PubMed ID: 23319583   DOI: 10.1074/jbc.M112.426080
9290  Hirohiko Okamura, Di Yang, Kaya Yoshida, Tatsuji Haneji  Protein Phosphatase 2A Cα Is Involved in Osteoclastogenesis by Regulating RANKL and OPG Expression in Osteoblasts  FEBS Lett  2013  587(1):48-53  PubMed ID: 23183242   DOI: 10.1016/j.febslet.2012.10.041
12258  Kazuhiro Nakaya, Makoto Ayaori, Harumi Uto-Kondo, Grace Megumi Sotherden, Takafumi Nishida, Haruka Katamoto, Yuko Miura, Shunichi Takiguchi, Emi Yakushiji, Maki Iizuka, Masatsune Ogura, Makoto Sasaki, Makiko Yogo, Tomohiro Komatsu, Takeshi Adachi, Chizuko Maruyama, Katsunori Ikewaki  Overexpression of stearoyl-coenzyme A desaturase 1 in macrophages promotes reverse cholesterol transport  Biochim Biophys Acta  2013  1831(8):1402-11  PubMed ID: 23747827   DOI: 10.1016/j.bbalip.2013.05.009
4394  Suzuki S, Nishio SI, Ishii H, Sekido T, Takeshige K, Ohkubo Y, Hiwatashi D, Takeda T, Komatsu M.  Possible roles of the AP-1 site in the cytosolic T3 binding protein promoter and insights into its physiological significance.  Horm Metab Res  2013  45(7):501-6  PubMed ID: 23508717   DOI: 10.1055/s-0033-1337933
14403  Tsolmongyn B, Koide N, Odkhuu E, Haque A, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Lipopolysaccharide prevents valproic acid-induced apoptosis via activation of nuclear factor-κB and inhibition of p53 activation  Cell Immunol  2013  282(2):100-5  PubMed ID: 23770718   DOI: 10.1016/j.cellimm.2013.04.011
15324  Rui Tada, Yusuke Koide, Mitsuaki Yamamuro, Akira Hidaka, Koichiro Nagao, Yoichi Negishi, Yukihiko Aramaki  Maleylated-BSA induces TNF-α production through the ERK and NF-κB signaling pathways in murine RAW264.7 macrophages  Open Journal of Immunology  2013  3:184-189    DOI: 10.4236/oji.2013.34023
15325  Yuka Takasugi, Futoshi Kurai, Issei Kazume, Masaki Otsuka, Yoichi Negishi, Rui Tada, Yukihiko Aramaki  Down Regulation of MyD88 in Macrophages Treated with Liposomes Composed of Phosphatidylserine  Pharmacology & Pharmacy  2013  4:248-254    DOI: 10.4236/pp.2013.42035
15326  Yuko Katao, Hirofumi Sawai, Mika Shishido, Aki Omae, Wen Liao, Kaoru Inami, Naoyuki Matsumoto  Augmentation of RANKL-induced osteoclast differentiation by Z-VAD-fmk, a pan-caspase inhibitor  Journal of Osaka Dental University  2013  47:41-46    DOI: 10.18905/jodu.47.1_41
15327  Fumiaki Shima, Koshi Kawakami, Takami Akagi, Eiko Mochizuki, Tetsuya Tsuda, Susumu Kuwabata, Mitsuru Akashi  Simple Observation of the Interaction between Nanoparticles and Cells by Scanning Electron Microscopy Employing Ionic Liquid  Bulletin of the Chemical Society of Japan  2013  86:153-158    DOI: 10.1246/bcsj.20120227
15328  Fujii M, Kawai K, Egami Y, Araki N.  Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation  Sci Rep  2013  3:2385  PubMed ID: 23924974   DOI: 10.1038/srep02385
15329  Muramatsu S, Tanaka S, Mogushi K, Adikrisna R, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Nakayama K, Tanaka H, Yamaoka S, Arii S.  Visualization of stem cell features in human hepatocellular carcinoma reveals in vivo significance of tumor-host interaction and clinical course  Hepatology  2013  58(1):218-28  PubMed ID: 23447025   DOI: 10.1002/hep.26345
15330  Nishimura M, Nii T, Trimova G, Miura S, Umezawa K, Ushiyama A, Kubota T.  The NF-κB specific inhibitor DHMEQ prevents thrombus formation in a mouse model of antiphospholipid syndrome  J Nephropathol  2013  2(2):114-21  PubMed ID: 24475437   DOI: 10.12860/JNP.2013.19
15331  Hiroshi HAYASHI, Yosuke UJII, Seiji GODA, Naoyuki MATSUMOTO  Effect of VCAM-1 on the Differentiation into Osteoclast  Journal of Oral Tissue Engineering  2013  11:154-162    DOI: 10.11223/jarde.11.154
15332  Higashimura Y, Naito Y, Takagi T, Mizushima K, Hirai Y, Harusato A, Ohnogi H, Yamaji R, Inui H, Nakano Y, Yoshikawa T.  Oligosaccharides from agar inhibit murine intestinal inflammation through the induction of heme oxygenase-1 expression  J Gastroenterol  2013  48(8):897-909  PubMed ID: 23188093   DOI: 10.1007/s00535-012-0719-4
15333  Tatsuya Murakami, Masashi Nakatani, Masahiro Kokubo, Hirotaka Nakatsuji, Mami Inada, Hiroshi Imahori, Masako Yudasaka, Sumio Iijima, Kunihiro Tsuchida  Mechanism of Cell Interactions with Water-Dispersed Carbon Nanohorns  Nanoscience and Nanotechnology Letters  2013  5:402-407    DOI: 10.1166/nnl.2013.1544
15334  Tanaka K, Ishihara T, Sugizaki T, Kobayashi D, Yamashita Y, Tahara K, Yamakawa N, Iijima K, Mogushi K, Tanaka H, Sato K, Suzuki H, Mizushima T.  Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease  Nat Commun  2013  4:2686  PubMed ID: 24189798   DOI: 10.1038/ncomms3686
15335  Seikou Kim, Kouichi Yamamoto, Yusuke Nakamura, Yuichi Otoyo, Atsushi Yamatodani  A Possible Mechanism of Cisplatin-Induced Tumor Necrosis Factor (TNF)-α Production in Murine Macrophages  Pharmacology & Pharmacy  2013  4:146-151    DOI: 10.4236/pp.2013.42021
15336  Tadahiro Etoh, Yong P. Kim, Masahiko Hayashi, Michiko Suzawa, Shiming Li, Chi-Tang Ho, Kanki Komiyama  Inhibitory effect of a formulated extract from multiple citrus peels on LPS-induced inflammation in RAW 246.7 macrophages  Functional Foods in Health and Disease  2013  3:242    DOI: 10.31989/ffhd.v3i6.50
15337  Phyu Phyu Khine Zar, Kozue Sakao, Fumio Hashimoto, Akiko Morishita, Makoto Fujii, Koji Wada, De-Xing Hou  Antioxidant and anti-inflammatory activities of loquat (Eriobotrya japonica) tea  Functional Foods in Health and Disease  2013  3:447    DOI: 10.31989/ffhd.v3i11.32
15773  Xi Yang, Yingnan Yang, Min Shi, Yuepeng Wang, Zhenya Zhang, Yifeng Lu  Optimisation of Anthocyanin Extraction from Purple Pitaya and Verification of Antioxidant Properties, Antiproliferative Activity and Macrophage Proliferation Activity  International Journal of Biology  2013  5    DOI: 10.5539/ijb.v5n3p19
16086  Kawabata K, Sugiyama Y, Sakano T, Ohigashi H.  Flavonols enhanced production of anti-inflammatory substance(s) by Bifidobacterium adolescentis: prebiotic actions of galangin, quercetin, and fisetin  Biofactors  2013  39(4):422-9  PubMed ID: 23554103   DOI: 10.1002/biof.1081
17188  Luquain-Costaz C, Lefai E, Arnal-Levron M, Markina D, Sakaï S, Euthine V, Makino A, Guichardant M, Yamashita S, Kobayashi T, Lagarde M, Moulin P, Delton-Vandenbroucke I.  Bis(monoacylglycero)phosphate accumulation in macrophages induces intracellular cholesterol redistribution, attenuates liver-X receptor/ATP-Binding cassette transporter A1/ATP-binding cassette transporter G1 pathway, and impairs cholesterol efflux  Arterioscler Thromb Vasc Biol  2013  33(8):1803-11  PubMed ID: 23788762   DOI: 10.1161/ATVBAHA.113.301857
7589  Funakoshi T, Yamashita K, Ichikawa N, Fukai M, Suzuki T, Goto R, Oura T, Kobayashi N, Katsurada T, Ichihara S, Ozaki M, Umezawa K, Todo S.  A novel NF-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice.  J Crohns Colitis  2012  6:215-25  PubMed ID: 22325176   DOI: 10.1016/j.crohns.2011.08.011
7599  Takano K, Sato K, Negishi Y, Aramaki Y.  Involvement of actin cytoskeleton in macrophage apoptosis induced by cationic liposomes.  Arch. Biochem. Biophys.  2012  518:89-94  PubMed ID: 22203089   DOI: 10.1016/
7605  Odkhuu E, Koide N, Haque A, Tsolmongyn B, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T.  Inhibition of receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast formation by pyrroloquinoline quinine (PQQ).  Immunol. Lett.  2012  142:34-40  PubMed ID: 22193059   DOI: 10.1016/j.imlet.2011.12.001
7608  Takahashi K, Sugiyama T, Tokoro S, Neri P, Mori H.  Inhibition of interferon-γ-induced nitric oxide production by 10-hydroxy-trans-2-decenoic acid through inhibition of interferon regulatory factor-8 induction.  Cell. Immunol.  2012  273:73-8  PubMed ID: 22177846   DOI: 10.1016/j.cellimm.2011.11.004
7609  Uto T, Morinaga O, Tanaka H, Shoyama Y.  Analysis of the synergistic effect of glycyrrhizin and other constituents in licorice extract on lipopolysaccharide-induced nitric oxide production using knock-out extract.  Biochem. Biophys. Res. Commun.  2012  417:473-8  PubMed ID: 22178686   DOI: 10.1016/j.bbrc.2011.11.143
7621  Nakagawa S, Arai Y, Kishida T, Hiraoka N, Tsuchida S, Inoue H, Sakai R, Mazda O, Kubo T.  Lansoprazole inhibits nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells.  Inflammation  2012  35:1062-8  PubMed ID: 22134422   DOI: 10.1007/s10753-011-9412-7
7639  Uto T, Qin GW, Morinaga O, Shoyama Y.  17-Hydroxy-jolkinolide B, a diterpenoid from Euphorbia fischeriana, inhibits inflammatory mediators but activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine macrophages.  Int. Immunopharmacol.  2012  12:101-9  PubMed ID: 22080918   DOI: 10.1016/j.intimp.2011.10.020
7667  Uchida M, Oyanagi E, Kremenik MJ, Sasaki J, Yano H.  Interferon-beta, but not tumor necrosis factor-alpha, production in response to poly I:C is maintained despite exhaustive exercise in mice.  J Physiol Sci  2012  62:59-62  PubMed ID: 21968540   DOI: 10.1007/s12576-011-0177-4
7678  Sugiyama T, Takahashi K, Tokoro S, Gotou T, Neri P, Mori H.  Inhibitory effect of 10-hydroxy-trans-2-decenoic acid on LPS-induced IL-6 production via reducing IκB-ζ expression.  Innate Immun  2012  18:429-37  PubMed ID: 21948282   DOI: 10.1177/1753425911416022
18461  Itoh T, Ando M, Tsukamasa Y, Wakimoto T, Nukaya H.  Whiskey congeners suppress LPS/IFNγ-induced NO production in murine macrophage RAW 264 cells by inducing heme oxygenase-1 expression  J Agric Food Chem  2012  60(51):12491-500  PubMed ID: 23199195   DOI: 10.1021/jf3040385
18733  Shi M, Yang Y, Guan D, Zhang Y, Zhang Z.  Bioactivity of the crude polysaccharides from fermented soybean curd residue by Flammulina velutipes  Carbohydr Polym  2012  89(4):1268-76  PubMed ID: 24750941   DOI: 10.1016/j.carbpol.2012.04.047
4881  Honda H, Nagai Y, Matsunaga T, Saitoh S, Akashi-Takamura S, Hayashi H, Fujii I, Miyake K, Muraguchi A, Takatsu K.  Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner.  J Leukoc Biol  2012  91(6):967-76  PubMed ID: 22422925   DOI: 10.1189/jlb.0112038
5417  Echigo R, Shimohata N, Karatsu K, Yano F, Kayasuga-Kariya Y, Fujisawa A, Ohto T, Kita Y, Nakamura M, Suzuki S, Mochizuki M, Shimizu T, Chung UI, Sasaki N.  Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage.  J Transl Med  2012  10:80  PubMed ID: 22546323   DOI: 10.1186/1479-5876-10-80
6552  Takarada T, Takarada-Iemata M, Takahata Y, Yamada D, Yamamoto T, Nakamura Y, Hinoi E, Yoneda Y.  Osteoclastogenesis is negatively regulated by D-serine produced by osteoblasts.  J Cell Physiol  2012  227(10):3477-87  PubMed ID: 22252936   DOI: 10.1002/jcp.24048
9092  Hiroyasu Tsutsuki, Kinnosuke Yahiro, Kotaro Suzuki, Akira Suto, Kohei Ogura, Sayaka Nagasawa, Hideshi Ihara, Takeshi Shimizu, Hiroshi Nakajima, Joel Moss, Masatoshi Noda  Subtilase Cytotoxin Enhances Escherichia Coli Survival in Macrophages by Suppression of Nitric Oxide Production Through the Inhibition of NF-κB Activation  Infect Immun  2012  80 (11), 3939-51  PubMed ID: 22949549   DOI: 10.1128/IAI.00581-12
9246  Yoshikazu Morita, Aiko Ono-Ohmachi, Satoshi Higurashi, Hiroaki Matsuyama, Atsushi Serizawa, Tatsuo Takeya  The bone-strengthening activity of milk basic protein is not dependent on lactoferrin  International Dairy Journal  2012  27:40-46    DOI: 10.1016/j.idairyj.2012.07.003
10965  Makoto Ayaori, Emi Yakushiji, Masatsune Ogura, Kazuhiro Nakaya, Tetsuya Hisada, Harumi Uto-Kondo, Shunichi Takiguchi, Yoshio Terao, Makoto Sasaki, Tomohiro Komatsu, Maki Iizuka, Makiko Yogo, Yoshinari Uehara, Hiroyuki Kagechika, Tsuyoshi Nakanishi, Katsunori Ikewaki  Retinoic acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages  Biochim Biophys Acta  2012  1821(4):561-72  PubMed ID: 22353356   DOI: 10.1016/j.bbalip.2012.02.004
15342  Toshiya KAWASAKI, Seiji GODA, Naoyuki MATSUMOTO  Effect of Akt on the Differentiation into Osteoclasts Caused by RANKL Stimulation  Journal of Oral Tissue Engineering  2012  10:67-76    DOI: 10.11223/jarde.10.67
15343  Iizuka M, Ayaori M, Uto-Kondo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Sasaki M, Komatsu T, Yogo M, Kishimoto Y, Kondo K, Ikewaki K.  Astaxanthin enhances ATP-binding cassette transporter A1/G1 expressions and cholesterol efflux from macrophages  J Nutr Sci Vitaminol (Tokyo)  2012  58(2):96-104  PubMed ID: 22790567   DOI: 10.3177/jnsv.58.96
15344  Kakutani R, Adachi Y, Takata H, Kuriki T, Ohno N.  Essential role of Toll-like receptor 2 in macrophage activation by glycogen  Glycobiology  2012  22(1):146-59  PubMed ID: 21873606   DOI: 10.1093/glycob/cwr122
15345  Miyashita K, Oyama T, Sakuta T, Tokuda M, Torii M.  Anandamide induces matrix metalloproteinase-2 production through cannabinoid-1 receptor and transient receptor potential vanilloid-1 in human dental pulp cells in culture  J Endod  2012  38(6):786-90  PubMed ID: 22595113   DOI: 10.1016/j.joen.2012.02.025
15346  Choi SH, Ahn JB, Kozukue N, Kim HJ, Nishitani Y, Zhang L, Mizuno M, Levin CE, Friedman M.  Structure-activity relationships of α-, β(1)-, γ-, and δ-tomatine and tomatidine against human breast (MDA-MB-231), gastric (KATO-III), and prostate (PC3) cancer cells  J Agric Food Chem  2012  60(15):3891-9  PubMed ID: 22482398   DOI: 10.1021/jf3003027
7558  Bandow K, Kusuyama J, Shamoto M, Kakimoto K, Ohnishi T, Matsuguchi T.  LPS-induced chemokine expression in both MyD88-dependent and -independent manners is regulated by Cot/Tpl2-ERK axis in macrophages  FEBS Lett  2012  586(10):1540-6  PubMed ID: 22673523   DOI: 10.1016/j.febslet.2012.04.018
7633  Yamamoto H, Abe Y, Miyazato A, Tanno D, Tanaka M, Miyasaka T, Ishii K, Kawakami K.  Cryptococcus neoformans suppresses the activation of bone marrow-derived dendritic cells stimulated with its own DNA, but not with DNA from other fungi.  FEMS Immunol. Med. Microbiol.  2011  63:363-72  PubMed ID: 22092563   DOI: 10.1111/j.1574-695X.2011.00859.x
7702  Chen J, Qin S, Xiao J, Tanigawa S, Uto T, Hashimoto F, Fujii M, Hou DX.  A genome-wide microarray highlights the antiinflammatory genes targeted by oolong tea theasinensin A in macrophages.  Nutr Cancer  2011  63:1064-73  PubMed ID: 21864060   DOI: 10.1080/01635581.2011.596643
7704  Ozasa H, Ayaori M, Iizuka M, Terao Y, Uto-Kondo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Uehara Y, Ogura M, Sasaki M, Komatsu T, Horii S, Mochizuki S, Yoshimura M, Ikewaki K.  Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: findings from in vitro and ex vivo studies.  Atherosclerosis  2011  219:141-50  PubMed ID: 21862012   DOI: 10.1016/j.atherosclerosis.2011.07.113
7725  Sakamoto T, Yamaguchi Y, Goto T, Takahashi N, Kawada T.  An in vitro analysis system using a fluorescence protein reporter for evaluating anti-inflammatory effects in macrophages.  Biosci. Biotechnol. Biochem.  2011  75:1582-7  PubMed ID: 21821941   DOI: 10.1271/bbb.110278
7745  Itoh T, Hamada N, Terazawa R, Ito M, Ohno K, Ichihara M, Nozawa Y, Ito M.  Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.  Biochem. Biophys. Res. Commun.  2011  411:143-9  PubMed ID: 21723254   DOI: 10.1016/j.bbrc.2011.06.116
7750  Fujimoto A, Akifusa S, Hirofuji T, Yamashita Y.  Involvement of suppressor of cytokine signaling-1 in globular adiponectin-induced granulocyte colony-stimulating factor in RAW 264 cell.  Mol. Immunol.  2011  48:2052-8  PubMed ID: 21764457   DOI: 10.1016/j.molimm.2011.06.440
7789  Abiko Y, Miura T, Phuc BH, Shinkai Y, Kumagai Y.  Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole.  Toxicol. Appl. Pharmacol.  2011  255:32-9  PubMed ID: 21651925   DOI: 10.1016/j.taap.2011.05.013
7794  Haque A, Noman AS, Koide N, Odkhuu E, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T.  An ADP ribosylation factor-GTPase activating protein negatively regulates the production of proinflammatory mediators in response to lipopolysaccharide.  Cancer Immunol. Immunother.  2011  60:1439-46  PubMed ID: 21644032   DOI: 10.1007/s00262-011-1048-9
7850  Egusa H, Doi M, Saeki M, Fukuyasu S, Akashi Y, Yokota Y, Yatani H, Kamisaki Y.  The small molecule harmine regulates NFATc1 and Id2 expression in osteoclast progenitor cells.  Bone  2011  49:264-74  PubMed ID: 21504804   DOI: 10.1016/j.bone.2011.04.003
7851  Akagi T, Shima F, Akashi M.  Intracellular degradation and distribution of protein-encapsulated amphiphilic poly(amino acid) nanoparticles.  Biomaterials  2011  32:4959-67  PubMed ID: 21482432   DOI: 10.1016/j.biomaterials.2011.03.049
7901  Yamazaki Y, Kawano Y.  Inhibitory effects of herbal alkaloids on the tumor necrosis factor-α and nitric oxide production in lipopolysaccharide-stimulated RAW264 macrophages.  Chem. Pharm. Bull.  2011  59:388-91  PubMed ID: 21372424   DOI: 10.1248/cpb.59.388
7921  Kurio N, Shimo T, Fukazawa T, Takaoka M, Okui T, Hassan NM, Honami T, Hatakeyama S, Ikeda M, Naomoto Y, Sasaki A.  Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo.  Exp. Cell Res.  2011  317:1134-46  PubMed ID: 21338601   DOI: 10.1016/j.yexcr.2011.02.008
7949  Arisaka M, Takano K, Negishi Y, Arima H, Aramaki Y.  Involvement of lipid rafts in macrophage apoptosis induced by cationic liposomes.  Arch. Biochem. Biophys.  2011  508:72-7  PubMed ID: 21315683   DOI: 10.1016/
7966  Ichioka M, Suganami T, Tsuda N, Shirakawa I, Hirata Y, Satoh-Asahara N, Shimoda Y, Tanaka M, Kim-Saijo M, Miyamoto Y, Kamei Y, Sata M, Ogawa Y.  Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans.  Diabetes  2011  60:819-26  PubMed ID: 21282371   DOI: 10.2337/db10-0864
8010  Haque A, Koide N, Iftakhar-E-Khuda I, Noman AS, Odkhuu E, Badamtseren B, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Flavopiridol inhibits lipopolysaccharide-induced TNF-α production through inactivation of nuclear factor-κB and mitogen-activated protein kinases in the MyD88-dependent pathway.  Microbiol. Immunol.  2011  55:160-7  PubMed ID: 21204955   DOI: 10.1111/j.1348-0421.2010.00304.x
8052  Miyazaki T, Miyauchi S, Anada T, Imaizumi H, Suzuki O.  Evaluation of osteoclastic resorption activity using calcium phosphate coating combined with labeled polyanion.  Anal. Biochem.  2011  410:7-12  PubMed ID: 21078287   DOI: 10.1016/j.ab.2010.11.014
8058  Oshima H, Hioki K, Popivanova BK, Oguma K, Van Rooijen N, Ishikawa TO, Oshima M.  Prostaglandin E? signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors.  Gastroenterology  2011  140:596-607.e7  PubMed ID: 21070778   DOI: 10.1053/j.gastro.2010.11.007
8066  Yonezawa T, Hasegawa S, Asai M, Ninomiya T, Sasaki T, Cha BY, Teruya T, Ozawa H, Yagasaki K, Nagai K, Woo JT.  Harmine, a β-carboline alkaloid, inhibits osteoclast differentiation and bone resorption in vitro and in vivo.  Eur. J. Pharmacol.  2011  650:511-8  PubMed ID: 21047508   DOI: 10.1016/j.ejphar.2010.10.048
8067  Kamio N, Akifusa S, Yamashita Y.  Diacylglycerol kinase alpha regulates globular adiponectin-induced reactive oxygen species.  Free Radic. Res.  2011  45:336-41  PubMed ID: 21034360   DOI: 10.3109/10715762.2010.532495
8135  Fukata N, Uchida K, Kusuda T, Koyabu M, Miyoshi H, Fukui T, Matsushita M, Nishio A, Tabata Y, Okazaki K.  The effective therapy of cyclosporine A with drug delivery system in experimental colitis.  J Drug Target  2011  19:458-67  PubMed ID: 20804404   DOI: 10.3109/1061186X.2010.511224
8415  Tumurkhuu G, Koide N, Hiwasa T, Ookoshi M, Dagvadorj J, Abu Shadat Mohammod Noman, Iftakhar-E-Khuda I, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock.  Innate Immun  2011  17:97-105  PubMed ID: 20023007   DOI: 10.1177/1753425909353641
8455  Shikama Y, Kuroishi T, Nagai Y, Iwakura Y, Shimauchi H, Takada H, Sugawara S, Endo Y.  Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).  Innate Immun  2011  17:3-15  PubMed ID: 19897531   DOI: 10.1177/1753425909347508
15296  Oka H, Mori M, Kihara H.  F-spondin inhibits migration and differentiation of osteoclastic precursors  J Periodontol  2011  82(12):1776-83  PubMed ID: 21488757   DOI: 10.1902/jop.2011.110111
15348  Oshima H, Popivanova BK, Oguma K, Kong D, Ishikawa TO, Oshima M.  Activation of epidermal growth factor receptor signaling by the prostaglandin E(2) receptor EP4 pathway during gastric tumorigenesis  Cancer Sci  2011  102(4):713-9  PubMed ID: 21205091   DOI: 10.1111/j.1349-7006.2011.01847.x
15349  Sugiyama K, Kawakami H, Kamata Y, Sugita-Konishi Y.  Effect of a combination of deoxynivalenol and nivalenol on lipopolisaccharide-induced nitric oxide production by mouse macrophages  Mycotoxin Res  2011  27(1):57-62  PubMed ID: 23605623   DOI: 10.1007/s12550-010-0076-1
15350  Kizaki T, Maegawa T, Sakurai T, Ogasawara JE, Ookawara T, Oh-ishi S, Izawa T, Haga S, Ohno H.  Voluntary exercise attenuates obesity-associated inflammation through ghrelin expressed in macrophages  Biochem Biophys Res Commun  2011  413(3):454-9  PubMed ID: 21907183   DOI: 10.1016/j.bbrc.2011.08.117
15351  Terao Y, Ayaori M, Ogura M, Yakushiji E, Uto-Kondo H, Hisada T, Ozasa H, Takiguchi S, Nakaya K, Sasaki M, Komatsu T, Iizuka M, Horii S, Mochizuki S, Yoshimura M, Ikewaki K.  Effect of sulfonylurea agents on reverse cholesterol transport in vitro and vivo  J Atheroscler Thromb  2011  18(6):513-30  PubMed ID: 21636950   DOI: 10.5551/jat.7641
15352  Eisuke DOMAE, Yumiko OGAWA, Osamu TAKEUCHI, Yosuke UJII, Yu KATO, Toshiya KAWASAKI, Hiroshi HAYASHI, Reiko KOMASA, Naochika DOMAE, Seiji GODA, Takashi IKEO  The Effect of Lysenin on the Differentiation into Osteoclast Cells  Journal of Oral Tissue Engineering  2011  9:3-9    DOI: 10.11223/jarde.9.3
15353  Ishijima Y, Kawamura T, Kimura A, Kohno A, Okada T, Tsuji T, Watanabe Y.  Toll-like receptor 4-dependent adjuvant activity of Kakkon-to extract exists in the high molecular weight polysaccharide fraction  Int J Immunopathol Pharmacol  2011  24(1):43-54  PubMed ID: 21496386   DOI: 10.1177/039463201102400106
15354  Mukai S, Kitazawa R, Ishii J, Kondo T, Hakozaki A, Horiuchi K, Haraguch R, Mori K, Kitazawa S.  Identification and analysis of function of a novel splicing variant of mouse receptor activator of NF-κB  Mol Cell Biochem  2011  350(1-2):29-38  PubMed ID: 21153864   DOI: 10.1007/s11010-010-0679-z
15355  Takayuki Anno, Keiichi Motoyama, Taishi Higashi, Fumitoshi Hirayama, Kaneto Uekama, Hidetoshi Arima  Preparation and evaluation of polyamidoamine dendrimer (G2)/branched-β-cyclodextrin conjugate as a novel gene transfer carrier  Journal of Inclusion Phenomena and Macrocyclic Chemistry  2011  70:339-344    DOI: 10.1007/s10847-010-9868-3
15356  Cui H, Okuhira K, Ohoka N, Naito M, Kagechika H, Hirose A, Nishimaki-Mogami T.  Tributyltin chloride induces ABCA1 expression and apolipoprotein A-I-mediated cellular cholesterol efflux by activating LXRα/RXR  Biochem Pharmacol  2011  81(6):819-24  PubMed ID: 21219878   DOI: 10.1016/j.bcp.2010.12.023
15357  Di Guan, Zhenya Zhang, Yingnan Yang, Guoqing Xing, Jiqiang Liu  Immunomodulatory Activity of Polysaccharide from the Roots of Actinidia kolomikta on Macrophages  International Journal of Biology  2011  3    DOI: 10.5539/ijb.v3n2p3
15359  Aoyagi Y, Adachi Y, Ozawa K, Yokomizo C, Gui MY, Jin YR, Li XW, Ohno N, Takeya K.  Synthesis of rabdokunmin C analogues and their inhibitory effect on NF-κB activation  Bioorg Med Chem  2011  19(7):2450-7  PubMed ID: 21393004   DOI: 10.1016/j.bmc.2011.02.002
8050  Hou DX, Masuzaki S, Tanigawa S, Hashimoto F, Chen J, Sogo T, Fujii M.  Oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (LPS)-activated mouse macrophages: structure-activity relationship and molecular mechanisms.  J. Agric. Food Chem.  2010  58:12735-43  PubMed ID: 21082860   DOI: 10.1021/jf103605j
8060  Ueda H, Ippoushi K, Takeuchi A.  Repeated oral administration of a squeezed ginger (Zingiber officinale) extract augmented the serum corticosterone level and had anti-inflammatory properties.  Biosci. Biotechnol. Biochem.  2010  74:2248-52  PubMed ID: 21071834   DOI: 10.1271/bbb.100456
8085  Sakagami H, Zhou L, Kawano M, Thet MM, Tanaka S, Machino M, Amano S, Kuroshita R, Watanabe S, Chu Q, Wang QT, Kanamoto T, Terakubo S, Nakashima H, Sekine K, Shirataki Y, Zhang CH, Uesawa Y, Mohri K, Kitajima M, Oizumi H, Oizumi T.  Multiple biological complex of alkaline extract of the leaves of Sasa senanensis Rehder.  In Vivo  2010  24:735-43  PubMed ID: 20952742  
8102  Lee JW, Mase N, Yonezawa T, Seo HJ, Jeon WB, Cha BY, Nagai K, Woo JT.  Palmatine attenuates osteoclast differentiation and function through inhibition of receptor activator of nuclear factor-κb ligand expression in osteoblast cells.  Biol. Pharm. Bull.  2010  33:1733-9  PubMed ID: 20930384   DOI: 10.1248/bpb.33.1733
8113  Okui T, Shimo T, Fukazawa T, Kurio N, Hassan NM, Honami T, Takaoka M, Naomoto Y, Sasaki A.  Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction.  Mol. Cancer Ther.  2010  9:2960-9  PubMed ID: 20858724   DOI: 10.1158/1535-7163.MCT-10-0489
8136  Shikama Y, Nagai Y, Okada S, Oizumi T, Shimauchi H, Sugawara S, Endo Y.  Pro-IL-1β accumulation in macrophages by alendronate and its prevention by clodronate.  Toxicol. Lett.  2010  199:123-8  PubMed ID: 20804833   DOI: 10.1016/j.toxlet.2010.08.013
8148  Nakaya K, Ayaori M, Uto-Kondo H, Hisada T, Ogura M, Yakushiji E, Takiguchi S, Terao Y, Ozasa H, Sasaki M, Komatsu T, Ohsuzu F, Ikewaki K.  Cilostazol enhances macrophage reverse cholesterol transport in vitro and in vivo.  Atherosclerosis  2010  213:135-41  PubMed ID: 20723893   DOI: 10.1016/j.atherosclerosis.2010.07.024
8160  Kotani H, Tanabe H, Mizukami H, Makishima M, Inoue M.  Identification of a naturally occurring rexinoid, honokiol, that activates the retinoid X receptor.  J. Nat. Prod.  2010  73:1332-6  PubMed ID: 20695472   DOI: 10.1021/np100120c
8181  Nakatsuka R, Nozaki T, Shinohara M, Ohura K.  Dilazep decreases lipopolysaccharide-induced nitric oxide and TNF-alpha synthesis in RAW 264 cells.  J. Pharmacol. Sci.  2010  113:271-5  PubMed ID: 20647687   DOI: 10.1254/jphs.09286sc
8208  Yano H, Uchida M, Nakai R, Ishida K, Kato Y, Kawanishi N, Shiva D.  Exhaustive exercise reduces TNF-α and IFN-α production in response to R-848 via toll-like receptor 7 in mice.  Eur. J. Appl. Physiol.  2010  110:797-803  PubMed ID: 20602110   DOI: 10.1007/s00421-010-1560-1
8210  Shadat NM, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Retinoblastoma protein-interacting zinc finger 1 (RIZ1) regulates the proliferation of monocytic leukemia cells via activation of p53.  Cancer Invest.  2010  28:806-12  PubMed ID: 20594067   DOI: 10.3109/07357907.2010.494323
8214  Sakai H, Moriura Y, Notomi T, Kawawaki J, Ohnishi K, Kuno M.  Phospholipase C-dependent Ca2+-sensing pathways leading to endocytosis and inhibition of the plasma membrane vacuolar H+-ATPase in osteoclasts.  Am. J. Physiol., Cell Physiol.  2010  299:C570-8  PubMed ID: 20592242   DOI: 10.1152/ajpcell.00486.2009
8224  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nonaka K, Yamashita Y.  Involvement of the JAK-STAT pathway and SOCS3 in the regulation of adiponectin-generated reactive oxygen species in murine macrophage RAW 264 cells.  J. Cell. Biochem.  2010  111:597-606  PubMed ID: 20564237   DOI: 10.1002/jcb.22745
8228  Kato Y, Koide N, Komatsu T, Tumurkhuu G, Dagvadorj J, Kato K, Yokochi T.  Metformin attenuates production of nitric oxide in response to lipopolysaccharide by inhibiting MyD88-independent pathway.  Horm. Metab. Res.  2010  42:632-6  PubMed ID: 20560107   DOI: 10.1055/s-0030-1255033
8229  Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation.  Cell. Immunol.  2010  264:114-8  PubMed ID: 20557878   DOI: 10.1016/j.cellimm.2010.05.007
8249  Ohata S, Moriyama C, Yamashita A, Nishida T, Kusumoto C, Mochida S, Minami Y, Nakada J, Shomori K, Inagaki Y, Ohta Y, Matsura T.  Polaprezinc Protects Mice against Endotoxin Shock.  J Clin Biochem Nutr  2010  46:234-43  PubMed ID: 20490319   DOI: 10.3164/jcbn.09-125
8258  Yamaguchi N, Hamachi T, Kamio N, Akifusa S, Masuda K, Nakamura Y, Nonaka K, Maeda K, Hanazawa S, Yamashita Y.  Expression levels of adiponectin receptors and periodontitis.  J. Periodont. Res.  2010  45:296-300  PubMed ID: 20470261   DOI: 10.1111/j.1600-0765.2009.01222.x
8273  Xiao G, Miyazato A, Abe Y, Zhang T, Nakamura K, Inden K, Tanaka M, Tanno D, Miyasaka T, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Yamamoto N, Kunishima H, Hirakata Y, Kaku M, Kawakami K.  Activation of myeloid dendritic cells by deoxynucleic acids from Cordyceps sinensis via a Toll-like receptor 9-dependent pathway.  Cell. Immunol.  2010  263:241-50  PubMed ID: 20451901   DOI: 10.1016/j.cellimm.2010.04.006
8282  Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Retinoblastoma protein-interacting zinc finger 1 (RIZ1) participates in RANKL-induced osteoclast formation via regulation of NFATc1 expression.  Immunol. Lett.  2010  131:166-9  PubMed ID: 20417662   DOI: 10.1016/j.imlet.2010.04.006
8286  Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS.  Immunology  2010  131:59-66  PubMed ID: 20406300   DOI: 10.1111/j.1365-2567.2010.03274.x
8335  Kitagawa Y, Tohya Y, Ike F, Kajita A, Park SJ, Ishii Y, Kyuwa S, Yoshikawa Y.  Indirect ELISA and indirect immunofluorescent antibody assay for detecting the antibody against murine norovirus S7 in mice.  Exp. Anim.  2010  59:47-55  PubMed ID: 20224169   DOI: 10.1538/expanim.59.47
8368  Shimoda H, Shan SJ, Tanaka J, Seki A, Seo JW, Kasajima N, Tamura S, Ke Y, Murakami N.  Anti-inflammatory properties of red ginger (Zingiber officinale var. Rubra) extract and suppression of nitric oxide production by its constituents.  J Med Food  2010  13:156-62  PubMed ID: 20136450   DOI: 10.1089/jmf.2009.1084
8369  Tsukamoto H, Fukudome K, Takao S, Tsuneyoshi N, Kimoto M.  Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.  Int. Immunol.  2010  22:271-80  PubMed ID: 20133493   DOI: 10.1093/intimm/dxq005
8372  Arisaka M, Nakamura T, Yamada A, Negishi Y, Aramaki Y.  Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells.  FEBS Lett.  2010  584:1016-20  PubMed ID: 20122929   DOI: 10.1016/j.febslet.2010.01.055
8373  Hakozaki A, Yoda M, Tohmonda T, Furukawa M, Hikata T, Uchikawa S, Takaishi H, Matsumoto M, Chiba K, Horiuchi K, Toyama Y.  Receptor activator of NF-kappaB (RANK) ligand induces ectodomain shedding of RANK in murine RAW264.7 macrophages.  J. Immunol.  2010  184:2442-8  PubMed ID: 20118276   DOI: 10.4049/jimmunol.0901188
8396  Suzuki T, Chang MO, Kitajima M, Takaku H.  Baculovirus activates murine dendritic cells and induces non-specific NK cell and T cell immune responses.  Cell. Immunol.  2010  262:35-43  PubMed ID: 20060108   DOI: 10.1016/j.cellimm.2009.12.005
8426  Hirai S, Uemura T, Mizoguchi N, Lee JY, Taketani K, Nakano Y, Hoshino S, Tsuge N, Narukami T, Yu R, Takahashi N, Kawada T.  Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages.  Mol Nutr Food Res  2010  54:797-804  PubMed ID: 19998383   DOI: 10.1002/mnfr.200900208
8456  Fujimoto A, Akifusa S, Kamio N, Hirofuji T, Nonaka K, Yamashita Y.  Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species.  Free Radic. Res.  2010  44:128-34  PubMed ID: 19886750   DOI: 10.3109/10715760903348328
8462  Matsubara T, Ikeda F, Hata K, Nakanishi M, Okada M, Yasuda H, Nishimura R, Yoneda T.  Cbp recruitment of Csk into lipid rafts is critical to c-Src kinase activity and bone resorption in osteoclasts.  J. Bone Miner. Res.  2010  25:1068-76  PubMed ID: 19874196   DOI: 10.1359/jbmr.091039
8465  Sugiyama K, Muroi M, Tanamoto K, Nishijima M, Sugita-Konishi Y.  Deoxynivalenol and nivalenol inhibit lipopolysaccharide-induced nitric oxide production by mouse macrophage cells.  Toxicol. Lett.  2010  192:150-4  PubMed ID: 19857559   DOI: 10.1016/j.toxlet.2009.10.020
8488  Kishimoto Y, Tani M, Uto-Kondo H, Iizuka M, Saita E, Sone H, Kurata H, Kondo K.  Astaxanthin suppresses scavenger receptor expression and matrix metalloproteinase activity in macrophages.  Eur J Nutr  2010  49:119-26  PubMed ID: 19784539   DOI: 10.1007/s00394-009-0056-4
5872  Chen J, Uto T, Tanigawa S, Yamada-Kato T, Fujii M, Hou DX.  Microarray-based determination of anti-inflammatory genes targeted by 6-(methylsulfinyl)hexyl isothiocyanate in macrophages.  Exp Ther Med  2010  1(1):33-40  PubMed ID: 23136589   DOI: 10.3892/etm_00000006
8207  Kaori Yoshino, Kaoru Saijo, Chikako Noro and Yukio Nakamura  Development of a simple method to determine the mouse strain from which cultured cell lines originated  Interdisciplinary Bio Central   2010  2:0014    DOI: 10.4051/ibc.2010.2.4.0014
8268  Miyazaki T, Miyauchi S, Tawada A, Anada T, Suzuki O.  Effect of chondroitin sulfate-E on the osteoclastic differentiation of RAW264 cells.  Dent Mater J  2010  29(4):403-10  PubMed ID: 20610874   DOI: 10.4012/dmj.2009-132
15360  Ii H, Imai T, Yaegaki K, Irie K, Ekuni D, Morita M.  Oral malodorous compound induces osteoclast differentiation without receptor activator of nuclear factor κB ligand  J Periodontol  2010  81(11):1691-7  PubMed ID: 20583917   DOI: 10.1902/jop.2010.100116
15361  Uto T, Suangkaew N, Morinaga O, Kariyazono H, Oiso S, Shoyama Y.  Eriobotryae folium extract suppresses LPS-induced iNOS and COX-2 expression by inhibition of NF-kappaB and MAPK activation in murine macrophages  Am J Chin Med  2010  38(5):985-94  PubMed ID: 20821828   DOI: 10.1142/S0192415X10008408
15362  Sasaki M, Miyakoshi M, Sato Y, Nakanuma Y.  Modulation of the microenvironment by senescent biliary epithelial cells may be involved in the pathogenesis of primary biliary cirrhosis  J Hepatol  2010  53(2):318-25  PubMed ID: 20570384   DOI: 10.1016/j.jhep.2010.03.008
15363  B. Sritularak, A. Tantituvanont1, P. Chanvorachote1, K. Meksawan1, T. Miyamoto2, Y. Kohno and K. Likhitwitayawuid  Flavonoids with free radical scavenging activity and nitric oxide inhibitory effect from the stem bark of Artocarpus gomezianus  Journal of Medicinal Plants Research  2010  4:387-392    DOI: 10.5897/JMPR09.433
15364  Takeichi SAKATA, Seiji GODA, Yumiko OGAWA, Takashi IKEO, Shosuke MORITA  β1-Integrin-Dependent Macrophage Migration is Regulated by MAP Kinase  Journal of Oral Tissue Engineering  2010  8:124-132    DOI: 10.11223/jarde.8.124
18302  Bouvier J, Zemski Berry KA, Hullin-Matsuda F, Makino A, Michaud S, Geloën A, Murphy RC, Kobayashi T, Lagarde M, Delton-Vandenbroucke I.  Selective decrease of bis(monoacylglycero)phosphate content in macrophages by high supplementation with docosahexaenoic acid  J Lipid Res  2009  50(2):243-55  PubMed ID: 18809971   DOI: 10.1194/jlr.M800300-JLR200
8359  Lee JW, Ahn JY, Hasegawa S, Cha BY, Yonezawa T, Nagai K, Seo HJ, Jeon WB, Woo JT.  Inhibitory effect of luteolin on osteoclast differentiation and function.  Cytotechnology  2009  61:125-34  PubMed ID: 20162352   DOI: 10.1007/s10616-010-9253-5
8495  Katsuura S, Imamura T, Bando N, Yamanishi R.  beta-Carotene and beta-cryptoxanthin but not lutein evoke redox and immune changes in RAW264 murine macrophages.  Mol Nutr Food Res  2009  53:1396-405  PubMed ID: 19760679   DOI: 10.1002/mnfr.200800566
8549  Shioiri T, Muroi M, Hatao F, Nishida M, Ogawa T, Mimura Y, Seto Y, Kaminishi M, Tanamoto K.  Caspase-3 is activated and rapidly released from human umbilical vein endothelial cells in response to lipopolysaccharide.  Biochim. Biophys. Acta  2009  1792:1011-8  PubMed ID: 19559790   DOI: 10.1016/j.bbadis.2009.06.006
8550  Kamio N, Akifusa S, Yamaguchi N, Nonaka K, Yamashita Y.  Anti-inflammatory activity of a globular adiponectin function on RAW 264 cells stimulated by lipopolysaccharide from Aggregatibacter actinomycetemcomitans.  FEMS Immunol. Med. Microbiol.  2009  56:241-7  PubMed ID: 19552715   DOI: 10.1111/j.1574-695X.2009.00573.x
8551  Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Thalidomide inhibits lipopolysaccharide-induced nitric oxide production and prevents lipopolysaccharide-mediated lethality in mice.  FEMS Immunol. Med. Microbiol.  2009  56:204-11  PubMed ID: 19538513   DOI: 10.1111/j.1574-695X.2009.00567.x
8578  Miyazato A, Nakamura K, Yamamoto N, Mora-Montes HM, Tanaka M, Abe Y, Tanno D, Inden K, Gang X, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Mitsutake K, Gow NA, Kaku M, Kawakami K.  Toll-like receptor 9-dependent activation of myeloid dendritic cells by Deoxynucleic acids from Candida albicans.  Infect. Immun.  2009  77:3056-64  PubMed ID: 19433551   DOI: 10.1128/IAI.00840-08
8589  Seddek Al, Mahmoud ME, Shiina T, Hirayama H, Iwami M, Miyazawa S, Nikami H, Takewaki T, Shimizu Y.  Extract from Calotropis procera latex activates murine macrophages.  J Nat Med  2009  63:297-303  PubMed ID: 19399577   DOI: 10.1007/s11418-009-0335-7
8637  Tomimori Y, Mori K, Koide M, Nakamichi Y, Ninomiya T, Udagawa N, Yasuda H.  Evaluation of pharmaceuticals with a novel 50-hour animal model of bone loss.  J. Bone Miner. Res.  2009  24:1194-205  PubMed ID: 19257825   DOI: 10.1359/jbmr.090217
8640  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nishihara T, Yamashita Y.  Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2.  Free Radic. Biol. Med.  2009  46:1308-16  PubMed ID: 19250964   DOI: 10.1016/j.freeradbiomed.2009.02.014
8641  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y.  Involvement of Ca(2+) in globular adiponectin-induced reactive oxygen species.  Biochem. Biophys. Res. Commun.  2009  381:649-53  PubMed ID: 19249286   DOI: 10.1016/j.bbrc.2009.02.115
8642  Hassan F, Islam S, Tumurkhuu G, Dagvadorj J, Naiki Y, Komatsu T, Koide N, Yoshida T, Yokochi T.  Involvement of interleukin-1 receptor-associated kinase (IRAK)-M in toll-like receptor (TLR) 7-mediated tolerance in RAW 264.7 macrophage-like cells.  Cell. Immunol.  2009  256:99-103  PubMed ID: 19251253   DOI: 10.1016/j.cellimm.2009.01.013
8648  Kasugai C, Morikawa A, Naiki Y, Koide N, Komatsu T, Yoshida T, Yokochi T.  Concanavalin A induces formation of osteoclast-like cells in RAW 264.7 mouse macrophage cells.  Immunopharmacol Immunotoxicol  2009  31:103-7  PubMed ID: 19234958   DOI: 10.1080/08923970802438417
8654  Iftakhar-E-Khuda I, Koide N, Hassan F, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Novel mechanism of U18666A-induced tumour necrosis factor-alpha production in RAW 264.7 macrophage cells.  Clin. Exp. Immunol.  2009  155:552-8  PubMed ID: 19220841   DOI: 10.1111/j.1365-2249.2008.03779.x
8663  Noman AS, Koide N, Hassan F, I-E-Khuda I, Dagvadorj J, Tumurkhuu G, Islam S, Naiki Y, Yoshida T, Yokochi T.  Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression.  Innate Immun  2009  15:33-41  PubMed ID: 19201823   DOI: 10.1177/1753425908099317
8691  Inden K, Kaneko J, Miyazato A, Yamamoto N, Mouri S, Shibuya Y, Nakamura K, Aoyagi T, Hatta M, Kunishima H, Hirakata Y, Itoh Y, Kaku M, Kawakami K.  Toll-like receptor 4-dependent activation of myeloid dendritic cells by leukocidin of Staphylococcus aureus.  Microbes Infect.  2009  11:245-53  PubMed ID: 19111627   DOI: 10.1016/j.micinf.2008.11.013
8739  Nakamura T, Kodama N, Arai Y, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ishikawa T, Ueno K, Yano S.  Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7.  J Nat Med  2009  63:21-7  PubMed ID: 18636311   DOI: 10.1007/s11418-008-0277-5
8740  Nakamura T, Kodama N, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ueno K, Ishikawa T, Yano S.  Inhibitory effect of the extracts from Thai medicinal plants on iNOS expression in mouse macrophage RAW 264.7.  J Nat Med  2009  63:107-10  PubMed ID: 18626726   DOI: 10.1007/s11418-008-0276-6
8742  Nakamura T, Kodama N, Oda M, Tsuchiya S, Arai Y, Kumamoto T, Ishikawa T, Ueno K, Yano S.  The structure-activity relationship between oxycoumarin derivatives showing inhibitory effects on iNOS in mouse macrophage RAW264.7 cells.  J Nat Med  2009  63:15-20  PubMed ID: 18607531   DOI: 10.1007/s11418-008-0268-6
18666  Huang Y, Nikolic D, Pendland S, Doyle BJ, Locklear TD, Mahady GB.  Effects of cranberry extracts and ursolic acid derivatives on P-fimbriated Escherichia coli, COX-2 activity, pro-inflammatory cytokine release and the NF-kappabeta transcriptional response in vitro  Pharm Biol  2009  47(1):18-25  PubMed ID: 20376297   DOI: 10.1080/13880200802397996
10145  Murakami M, Kawachi H, Ogawa K, Nishino Y, Funaba M.  Receptor expression modulates the specificity of transforming growth factor-beta signaling pathways.  Genes Cells  2009  14(4):469-82  PubMed ID: 19335617   DOI: 10.1111/j.1365-2443.2009.01283.x
8170  Tsuji M, Yamamoto H, Sato T, Mizuha Y, Kawai Y, Taketani Y, Kato S, Terao J, Inakuma T, Takeda E.  Dietary quercetin inhibits bone loss without effect on the uterus in ovariectomized mice.  J Bone Miner Metab  2009  27(6):673-81  PubMed ID: 19495926   DOI: 10.1007/s00774-009-0088-0
11020  Masayuki TAIRA et al  DNA Microarray Analyses of the Effects of LPS-stimulation and IC50 Nickel Ions on Gene Expressions of Mouse Macrophage-like Cell Line RAW264  Nano Biomedicine  2009  1:59-69    DOI: 10.11344/nano.1.59
12295  Ken Shirato, Takako Kizaki, Takuya Sakurai, Jun-Etsu Ogasawara, Yoshinaga Ishibashi, Takehiko Iijima, Chikako Okada, Izumi Noguchi, Kazuhiko Imaizumi, Naoyuki Taniguchi, Hideki Ohno  Hypoxia-inducible factor-1alpha suppresses the expression of macrophage scavenger receptor 1  Pflugers Arch  2009  459(1):93-103  PubMed ID: 19641936   DOI: 10.1007/s00424-009-0702-y
15368  Namba T, Tanaka K, Ito Y, Ishihara T, Hoshino T, Gotoh T, Endo M, Sato K, Mizushima T.  Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis  Am J Pathol  2009  174(5):1786-98  PubMed ID: 19359519   DOI: 10.2353/ajpath.2009.080864
15369  Iigo M, Alexander DB, Long N, Xu J, Fukamachi K, Futakuchi M, Takase M, Tsuda H.  Anticarcinogenesis pathways activated by bovine lactoferrin in the murine small intestine  Biochimie  2009  91(1):86-101  PubMed ID: 18634843   DOI: 10.1016/j.biochi.2008.06.012
15370  Aoyama T, Takeshita K, Kikuchi R, Yamamoto K, Cheng XW, Liao JK, Murohara T.  gamma-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice  Biochem Biophys Res Commun  2009  383(2):216-21  PubMed ID: 19345673   DOI: 10.1016/j.bbrc.2009.03.154
16614  Kajiura T, Takeda T, Sakata S, Sakamoto M, Hashimoto M, Suzuki H, Suzuki M, Benno Y.  Change of intestinal microbiota with elemental diet and its impact on therapeutic effects in a murine model of chronic colitis  Dig Dis Sci  2009  54(9):1892-900  PubMed ID: 19058004   DOI: 10.1007/s10620-008-0574-6
18313  Kyogoku K, Yoshida K, Watanabe H, Yamashita T, Kawabe Y, Motono M, Nishijima K, Kamihira M, Iijima S.  Production of recombinant tumor necrosis factor receptor/Fc fusion protein by genetically manipulated chickens  J Biosci Bioeng  2008  105(5):454-9  PubMed ID: 18558334   DOI: 10.1263/jbb.105.454
18331  Kang MS, Hirai S, Goto T, Kuroyanagi K, Lee JY, Uemura T, Ezaki Y, Takahashi N, Kawada T.  Dehydroabietic acid, a phytochemical, acts as ligand for PPARs in macrophages and adipocytes to regulate inflammation  Biochem Biophys Res Commun  2008  369(2):333-8  PubMed ID: 18267111   DOI: 10.1016/j.bbrc.2008.02.002
18376  Islam S, Hassan F, Tumurkhuu G, Dagvadorj J, Koide N, Naiki Y, Yoshida T, Yokochi T.  Receptor activator of nuclear factor-kappa B ligand induces osteoclast formation in RAW 264.7 macrophage cells via augmented production of macrophage-colony-stimulating factor  Microbiol Immunol  2008  52(12):585-90  PubMed ID: 19120972   DOI: 10.1111/j.1348-0421.2008.00076.x
8731  Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y.  Regulation of globular adiponectin-induced apoptosis by reactive oxygen/nitrogen species in RAW264 macrophages.  Free Radic. Biol. Med.  2008  45:1326-39  PubMed ID: 18775488   DOI: 10.1016/j.freeradbiomed.2008.08.005
8754  Yoshida H, Kwon AH, Habara K, Yamada M, Kaibori M, Kamiyama Y, Nishizawa M, Ito S, Okumura T.  Edaravone inhibits the induction of iNOS gene expression at transcriptional and posttranscriptional steps in murine macrophages.  Shock  2008  30:734-9  PubMed ID: 18496239   DOI: 10.1097/SHK.0b013e318173ea0b
5375  Nishida K, Kuchiiwa S, Oiso S, Futagawa T, Masuda S, Takeda Y, Yamada K.  Up-regulation of matrix metalloproteinase-3 in the dorsal root ganglion of rats with paclitaxel-induced neuropathy.  Cancer Sci  2008  99(8):1618-25  PubMed ID: 18754875   DOI: 10.1111/j.1349-7006.2008.00877.x
3578  Ando M, Tu W, Nishijima K, Iijima S.  Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs.  Biochem Biophys Res Commun  2008  369(3):878-83  PubMed ID: 18325328   DOI: 10.1016/j.bbrc.2008.02.111
6521  Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H.  Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9.  J Biol Chem  2008  283(36):24682-9  PubMed ID: 18617520   DOI: 10.1074/jbc.M709857200
6804  Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.  Thalidomide inhibits epidermal growth factor-induced cell growth in mouse and human monocytic leukemia cells via Ras inactivatio  Biochem Biophys Res Commun  2008  374(4):683-7  PubMed ID: 18662673   DOI: 10.1016/j.bbrc.2008.07.090
13756  Murakami M, Kondo S, Funaba M.  Expression and function of alternative splice variants of the mouse TGF-beta type I receptor  Cell Biol Int  2008  32(7):848-54  PubMed ID: 18474439   DOI: 10.1016/j.cellbi.2008.03.020
13958  Kawanishi N, Tanaka Y, Kato Y, Shiva D, Yano H.  Lipopolysaccharide-induced monocyte chemotactic protein-1 is enhanced by suppression of nitric oxide production, which depends on poor CD14 expression on the surface of skeletal muscle  Cell Biochem Funct  2008  26(4):486-9  PubMed ID: 18383566   DOI: 10.1002/cbf.1471
15371  Suzuki N, Yoshimura Y, Deyama Y, Suzuki K, Kitagawa Y.  Mechanical stress directly suppresses osteoclast differentiation in RAW264.7 cells  Int J Mol Med  2008  21(3):291-6  PubMed ID: 18288375  
15372  Ishii J, Kitazawa R, Mori K, McHugh KP, Morii E, Kondo T, Kitazawa S.  Lipopolysaccharide suppresses RANK gene expression in macrophages by down-regulating PU.1 and MITF  J Cell Biochem  2008  105(3):896-904  PubMed ID: 18759249   DOI: 10.1002/jcb.21886
15373  Yumiko Ogawa, Seiji Goda, Shosuke Morita  The Effect of Methyl-β-cyclodextrin on the Differentiation of RAW264 Cells into Osteoclasts  Oral Science International  2008  5:15-23    DOI: 10.1016/s1348-8643(08)80002-x
15375  Ken-ichiro Minato  Immunomodulation Activity of a Polysaccharide Fraction of a Culinary-Medicinal Mushroom, Pleurotus citrinopileatus Singer (Agaricomycetideae), in Vitro  International Journal of Medicinal Mushrooms  2008  10:235-244    DOI: 10.1615/intjmedmushr.v10.i3.40
15376  Oguma K, Oshima H, Aoki M, Uchio R, Naka K, Nakamura S, Hirao A, Saya H, Taketo MM, Oshima M.  Activated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells  EMBO J  2008  27(12):1671-81  PubMed ID: 18511911   DOI: 10.1038/emboj.2008.105
15377  Ryo Kakutani, Yoshiyuki Adachi, Hideki Kajiura, Hiroki Takata, Naohito Ohno, Takashi Kuriki  Stimulation of macrophage by enzymatically synthesized glycogen: the relationship between structure and biological activity  Biocatalysis and Biotransformation  2008  26:152-160    DOI: 10.1080/10242420701804541
16649  Yeh CM, Yeh CK, Hsu XY, Luo QM, Lin MY.  Extracellular expression of a functional recombinant Ganoderma lucidium immunomodulatory protein by Bacillus subtilis and Lactococcus lactis  Appl Environ Microbiol  2008  74(4):1039-49  PubMed ID: 18156317   DOI: 10.1128/AEM.01547-07
8850  Yamaguchi N, Kukita T, Li YJ, Martinez Argueta JG, Saito T, Hanazawa S, Yamashita Y.  Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.  FEMS Immunol. Med. Microbiol.  2007  49:28-34  PubMed ID: 17094790   DOI: 10.1111/j.1574-695X.2006.00164.x
18605  Islam S, Hassan F, Tumurkhuu G, Dagvadorj J, Koide N, Naiki Y, Mori I, Yoshida T, Yokochi T.  Bacterial lipopolysaccharide induces osteoclast formation in RAW 264.7 macrophage cells  Biochem Biophys Res Commun  2007  360(2):346-5  PubMed ID: 17597583   DOI: 10.1016/j.bbrc.2007.06.023
18607  Yanagishita T, Watanabe D, Akita Y, Nakano A, Ohshima Y, Tamada Y, Matsumoto Y.  Construction of novel in vitro epithelioid cell granuloma model from mouse macrophage cell line  Arch Dermatol Res  2007  299(8):399-403  PubMed ID: 17704931   DOI: 10.1007/s00403-007-0778-1
18906  Delton-Vandenbroucke I, Bouvier J, Makino A, Besson N, Pageaux JF, Lagarde M, Kobayashi T.  Anti-bis(monoacylglycero)phosphate antibody accumulates acetylated LDL-derived cholesterol in cultured macrophages  J Lipid Res  2007  48(3):543-52  PubMed ID: 17146116   DOI: 10.1194/jlr.M600266-JLR200
4889  Takayoshi Suganami, Kanami Tanimoto-Koyama, Junko Nishida, Michiko Itoh, Xunmei Yuan, Shinji Mizuarai, Hidehito Kotani, Shoji Yamaoka, Kensuke Miyake, Seiichiro Aoe, Yasutomi Kamei and Yoshihiro Ogawa  Role of the Toll-like Receptor 4/NF-κB Pathway in Saturated Fatty Acid−Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages  Arterioscler Thromb Vasc Biol  2007  27:84-91  PubMed ID: 17082484   DOI: 10.1161/01.ATV.0000251608.09329.9a
7269  Takarada T, Hinoi E, Kambe Y, Sahara K, Kurokawa S, Takahata Y, Yoneda Y.  Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative cytotoxicity of ascorbic acid.  Eur J Pharmacol  2007  575(1-3):1-11  PubMed ID: 17698058   DOI: 10.1016/j.ejphar.2007.07.041
7349  Ito M, Haito S, Furumoto M, Uehata Y, Sakurai A, Segawa H, Tatsumi S, Kuwahata M, Miyamoto K.  Unique uptake and efflux systems of inorganic phosphate in osteoclast-like cells.  Am J Physiol Cell Physiol  2007  292(1):C526-34  PubMed ID: 16971494   DOI: 10.1152/ajpcell.00357.2006
7354  Takahashi N, Udagawa N, Kobayashi Y, Suda T.  Generation of osteoclasts in vitro, and assay of osteoclast activity.  Methods Mol Med  2007  135:285-301  PubMed ID: 17951666   DOI: 10.1007/978-1-59745-401-8_18
7387  Murakami Y, Hirata A, Ito S, Shoji M, Tanaka S, Yasui T, Machino M, Fujisawa S.  Re-evaluation of cyclooxygenase-2-inhibiting activity of vanillin and guaiacol in macrophages stimulated with lipopolysaccharide.  Anticancer Res  2007  27(2):801-7  PubMed ID: 17465205  
10072  Yoshinari Uehara 1, Shin-ichiro Miura, Arnold von Eckardstein, Satomi Abe, Akihiro Fujii, Yoshino Matsuo, Stephan Rust, Stefan Lorkowski, Gerd Assmann, Tatsuo Yamada, Keijiro Saku  Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element  Atherosclerosis  2007  191(1):11-21  PubMed ID: 16730733   DOI: 10.1016/j.atherosclerosis.2006.04.018
12814  Uto T, Fujii M, Hou DX.  Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-gamma and 12-O-tetradecanoylphorbol-13-acetate  Oncol Rep  2007  17(1):233-8  PubMed ID: 17143503  
15374  Natalie Ohashi, Miho Nakamura, Akiko Nagai, Yumi Tanaka, Yasutaka Sekijima, Kimihiro Yamashita  Comparison of Hydroxyapatite with Carbonate Apatite in Osteoclastic Cell Resorptive Activity  Key Engineering Materials  2007  361-363:1039-1042    DOI: 10.4028/
15378  Yuki Kaneshita, Seiji Goda, Tatsuo Kawamoto  The effect of matrix metalloproteinase-9 on the differentiation into osteoclast cells on RAW264 cells  Orthodontic Waves  2007  66:122-128    DOI: 10.1016/j.odw.2007.09.003
15379  Kentaro Harutsugu, Kyoko Watanabe, Michiharu Daito  The role of anti immune response on adenosine stimulated macrophages  Pediatric Dental Journal  2007  1:40-46    DOI: 10.11411/pdj.17.40
15642  Junji TANAKA, Shao-Jie SHAN, Naoki KASAJIMA, Hiroshi SHIMODA  Suppressive Effect of Defatted Kiwi Fruit Seed Extract on Acute Inflammation and Skin Pigmentation  Food Science and Technology Research  2007  13:310-314    DOI: 10.3136/fstr.13.310
17689  Tanaka H, Tanabe N, Shoji M, Suzuki N, Katono T, Sato S, Motohashi M, Maeno M.  Nicotine and lipopolysaccharide stimulate the formation of osteoclast-like cells by increasing macrophage colony-stimulating factor and prostaglandin E2 production by osteoblasts  Life Sci  2006  78(15):1733-40  PubMed ID: 16266722   DOI: 10.1016/j.lfs.2005.08.017
8815  Taira M, Sasaki K, Saitoh S, Nezu T, Sasaki M, Kimura S, Terasaki K, Sera K, Narushima T, Araki Y.  Accumulation of element Ti in macrophage-like RAW264 cells cultured in medium with 1 ppm Ti and effects on cell viability, SOD production and TNF-alpha secretion.  Dent Mater J  2006  25:726-32  PubMed ID: 17338307   DOI: 10.4012/dmj.25.726
8917  Soji Fukumoto, Paramasari Dirgahayu, Kozue Nunomura, Haruyo Matsuura andKazumitsu Hirai  Suppression of LPS-induced Cyclooxygenase-2 (cox-2) Gene Expression in Mouse Macrophages by Excretory/Secretory Products of Spirometra erinaceieuropaei Plerocercoids  Yonago Acta Med.  2006  49:39-47   
18863  Hong J, Nakano Y, Yokomakura A, Ishihara K, Kim S, Kang YS, Ohuchi K.  Nitric oxide production by the vacuolar-type (H+)-ATPase inhibitors bafilomycin A1 and concanamycin A and its possible role in apoptosis in RAW 264.7 cells  J Pharmacol Exp Ther  2006  319(2):672-81  PubMed ID: 16895977   DOI: 10.1124/jpet.106.109280
18869  Hong J, Yokomakura A, Nakano Y, Ishihara K, Kaneda M, Onodera M, Nakahama K, Morita I, Niikura K, Ahn JW, Zee O, Ohuchi K.  Inhibition of vacuolar-type (H+)-ATPase by the cytostatic macrolide apicularen A and its role in apicularen A-induced apoptosis in RAW 264.7 cells  FEBS Lett  2006  580(11):2723-30  PubMed ID: 16647709   DOI: 10.1016/j.febslet.2006.04.031
18870  Lipopolysaccharide prevents apoptosis induced by brefeldin A, an endoplasmic reticulum stress agent, in RAW 264.7 cells  Lipopolysaccharide prevents apoptosis induced by brefeldin A, an endoplasmic reticulum stress agent, in RAW 264.7 cells  Biochem Biophys Res Commun  2006  340(2):589-96  PubMed ID: 16380090   DOI: 10.1016/j.bbrc.2005.12.050
6489  Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A.  TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.  Arthritis Res Ther  2006  8(5):R146  PubMed ID: 16945157   DOI: 10.1186/ar2038
6976  Nagai N, Anzawa T, Satoh Y, Suzuki T, Tajima K, Munekata M.  Activities of MC3T3-E1 cells cultured on gamma-irradiated salmon atelocollagen scaffold.  J Biosci Bioeng  2006  101(6):511-4  PubMed ID: 16935254   DOI: 10.1263/jbb.101.511
7020  Murakami Y, Shoji M, Ogiwara T, Tanaka S, Yokoe I, Fujisawa S.  Preventive effect of ortho dimer of butylated hydroxyanisole on activator protein-1 activation and cyclooxygenase-2 expression in macrophages stimulated by fimbriae of Porphyromonas gingivalis, an oral anaerobe.  Anticancer Res  2006  26(4B):2915-20  PubMed ID: 16886613  
7039  Funaba M, Nakaya K, Ikeda T, Murakami M, Tsuchida K, Sugino H.  Requirement of Smad3 for mast cell growth.  Cell Immunol  2006  240(1):47-52  PubMed ID: 16839529   DOI: 10.1016/j.cellimm.2006.06.002
11012  Mohammad Samiul Alam, Mohammad Hasan Zaki, Jun Yoshitake, Teruo Akuta, Takayuki Ezaki, Takaaki Akaike  Involvement of Salmonella enterica serovar Typhi RpoS in resistance to NO-mediated host defense against serovar Typhi infection  Microb Pathog  2006  40(3):116-25  PubMed ID: 16448800   DOI: 10.1016/j.micpath.2005.11.007
13660  Kimura Y, Sumiyoshi M, Suzuki T, Sakanaka M.  Antitumor and antimetastatic activity of a novel water-soluble low molecular weight beta-1, 3-D-glucan (branch beta-1,6) isolated from Aureobasidium pullulans 1A1 strain black yeast  Anticancer Res  2006  26(6B):4131-41  PubMed ID: 17201124  
13729  Imamura T, Bando N, Yamanishi R.  Beta-carotene modulates the immunological function of RAW264, a murine macrophage cell line, by enhancing the level of intracellular glutathione  Biosci Biotechnol Biochem  2006  70(9):2112-20.  PubMed ID: 16960387   DOI: 10.1271/bbb.60056
15381  KYOKO WATANABE, SHINYA SHIRASU, KIYOSHI DAITO, MASAHARU MOTOYAMA, YOSHITOMO OGAWA, KOJI NAKAI, KIYOSHI OHURA, MICHIHARU DAITO  Differentiation of the expression of A2a adenosine receptor in macrophage cell lines RAW264  ORAL THERAPEUTICS AND PHARMACOLOGY  2006  25:8-16    DOI: 10.11263/jsotp1982.25.8
15382  Hida S, Nagi-Miura N, Adachi Y, Ohno N.  Beta-glucan derived from zymosan acts as an adjuvant for collagen-induced arthritis  Microbiol Immunol  2006  50(6):453-61  PubMed ID: 16785717   DOI: 10.1111/j.1348-0421.2006.tb03814.x
15383  Casolaro M, Bottari S, Ito Y.  Vinyl polymers based on L-histidine residues. Part 2. Swelling and electric behavior of smart poly(ampholyte) hydrogels for biomedical applications  Biomacromolecules  2006  ;7(5):1439-48  PubMed ID: 16677025   DOI: 10.1021/bm0509671
15384  Funaba M, Murakami M, Ikeda T, Ogawa K, Tsuchida K, Sugino H.  Identification of tocopherol-associated protein as an activin/TGF-beta-inducible gene in mast cells  Biochim Biophys Acta  2006  1763(8):900-6  PubMed ID: 16872693   DOI: 10.1016/j.bbamcr.2006.06.002
3160  Wei, Ping, Taniguchi, Susumu, Sakai, Yoshiyuki, Imamura, Minako, Inoguchi, Toyoshi, Nawata, Hajime, Oda, Shinya, Nakabeppu, Yusaku, Nishimura, Junji, Ikuyama, Shoichiro  Expression of adipose differentiation-related protein (ADRP) is conjointly regulated by PU.1 and AP-1 in macrophages.  J Biochem  2005  138:399-412  PubMed ID: 16272134   DOI: 10.1093/jb/mvi136
2903  Shimomura-Shimizu M, Sugiyama K, Muroi M, Tanamoto K  Alachlor and carbaryl suppress lipopolysaccharide-induced iNOS expression by differentially inhibiting NF-kappaB activation.  Biochem Biophys Res Commun  2005  332:793-9  PubMed ID: 15907790   DOI: 10.1016/j.bbrc.2005.05.024
2922  Musikacharoen, Tipayaratn, Oguma, Asako, Yoshikai, Yasunobu, Chiba, Norika, Masuda, Akio, Matsuguchi, Tetsuya  Interleukin-15 induces IL-12 receptor beta1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling.  Blood  2005  105:711-20  PubMed ID: 15345588   DOI: 10.1182/blood-2004-03-0842
3365  Ito, Mikiko, Matsuka, Naoko, Izuka, Michiyo, Haito, Sakiko, Sakai, Yuko, Nakamura, Rie, Segawa, Hiroko, Kuwahata, Masashi, Yamamoto, Hironori, Pike, Wesley J, Miyamoto, Ken-ichi  Characterization of inorganic phosphate transport in osteoclast-like cells.  Am J Physiol Cell Physiol  2005  288:C921-31  PubMed ID: 15601753   DOI: 10.1152/ajpcell.00412.2004
3392  Aki, Daisuke, Mashima, Ryuichi, Saeki, Kazuko, Minoda, Yasumasa, Yamauchi, Moriyasu, Yoshimura, Akihiko  Modulation of TLR signalling by the C-terminal Src kinase (Csk) in macrophages.  Genes Cells  2005  10:357-68  PubMed ID: 15773898   DOI: 10.1111/j.1365-2443.2005.00839.x
3210  Hou, De-Xing, Yanagita, Takashi, Uto, Takuhiro, Masuzaki, Satoko, Fujii, Makoto  Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved.  Biochem Pharmacol  2005  70:417-25  PubMed ID: 15963474   DOI: 10.1016/j.bcp.2005.05.003
3190  Hassan, Ferdaus, Islam, Shamima, Mu, Mya Mya, Ito, Hiroyasu, Koide, Naoki, Mori, Isamu, Yoshida, Tomoaki, Yokochi, Takashi  Lipopolysaccharide prevents doxorubicin-induced apoptosis in RAW 264.7 macrophage cells by inhibiting p53 activation.  Mol Cancer Res  2005  3:373-9  PubMed ID: 16046548   DOI: 10.1158/1541-7786.MCR-05-0046
3098  Suganami, Takayoshi, Nishida, Junko, Ogawa, Yoshihiro  A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha.  Arterioscler Thromb Vasc Biol  2005  25:2062-2068  PubMed ID: 16123319   DOI: 10.1161/01.ATV.0000183883.72263.13
3209  Uto, Takuhiro, Fujii, Makoto, Hou, De-Xing  6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages.  Biochem Pharmacol  2005  70:1211-21  PubMed ID: 16139249   DOI: 10.1016/j.bcp.2005.07.011
9122  Kobayashi Y, Mizoguchi T, Take I, Kurihara S, Udagawa N, Takahashi N.  Prostaglandin E2 enhances osteoclastic differentiation of precursor cells through protein kinase A-dependent phosphorylation of TAK1.  J. Biol. Chem.  2005  280:11395-403  PubMed ID: 15647289   DOI: 10.1074/jbc.M411189200
2919  Abe T, Hemmi H, Miyamoto H, Moriishi K, Tamura S, Takaku H, Akira S, Matsuura Y.  Involvement of the Toll-like receptor 9 signaling pathway in the induction of innate immunity by baculovirus.  J Virol  2005  79(5):2847-58  PubMed ID: 15709004   DOI: 10.1128/JVI.79.5.2847-2858.2005
5921  Uto T, Fujii M, Hou DX.  Inhibition of lipopolysaccharide-induced cyclooxygenase-2 transcription by 6-(methylsulfinyl) hexyl isothiocyanate, a chemopreventive compound from Wasabia japonica (Miq.) Matsumura, in mouse macrophages.  Biochem Pharmacol  2005  70(12):1772-84  PubMed ID: 16256955   DOI: 10.1016/j.bcp.2005.09.023
6868  Hirata A, Murakami Y, Atsumi T, Shoji M, Ogiwara T, Shibuya K, Ito S, Yokoe I, Fujisawa S.  Ferulic acid dimer inhibits lipopolysaccharide-stimulated cyclooxygenase-2 expression in macrophages.  In Vivo  2005  19(5):849-53  PubMed ID: 16097437  
6869  Hirata A, Murakami Y, Shoji M, Kadoma Y, Fujisawa S.  Kinetics of radical-scavenging activity of hesperetin and hesperidin and their inhibitory activity on COX-2 expression.  Anticancer Res  2005  25(5):3367-74  PubMed ID: 16101151  
6873  Murakami Y, Ito S, Atsumi T, Fujisawa S.  Theoretical prediction of the relationship between phenol function and COX-2/AP-1 inhibition for ferulic acid-related compounds.  In Vivo  2005  19(6):1039-43  PubMed ID: 16277019  
6874  Okada N, Hirata A, Murakami Y, Shoji M, Sakagami H, Fujisawa S.  Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression by eugenol-related compounds.  Anticancer Res  2005  25(5):3263-9  PubMed ID: 16101137  
6875  Atsumi T, Murakami Y, Shibuya K, Tonosaki K, Fujisawa S.  Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression, by curcumin and its analog, alpha-diisoeugenol.  Anticancer Res  2005  25(6B):4029-36  PubMed ID: 16309195  
12262  Tomohiro Konno, Hirokazu Hasuda, Kazuhiko Ishihara, Yoshihiro Ito  Photo-immobilization of a phospholipid polymer for surface modification  Biomaterials  2005  26(12):1381-8  PubMed ID: 15482825   DOI: 10.1016/j.biomaterials.2004.04.047
12263  Hirokazu Hasuda , Oh Hyeong Kwon, Inn-Kyu Kang, Yoshihiro Ito  Synthesis of photoreactive pullulan for surface modification  Biomaterials  2005  26(15):2401-6  PubMed ID: 15585243   DOI: 10.1016/j.biomaterials.2004.07.065
15385  Kyoko Watanabe  Differentiation by LPS and IFN-γ of expression of adenosine receptors in macrophage cell lines RAW264 and J774  Pediatric Dental Journal  2005  15:43-51    DOI: 10.1016/s0917-2394(05)70028-8
15386  Koji Tatebayashi, Eiko Matsui, Hideo Kaneko, Toshiyuki Fukao, Kimiko Kasahara, Naomi Kondo  IL-12B Promoter Polymorphism Associated with Asthma and IL-12B Transcriptional Activity  Allergology International  2005  54:451-459    DOI: 10.2332/allergolint.54.451
15387  Kurozumi R, Takahashi M, Kojima S.  Involvement of mitochondrial peroxynitrite in nitric oxide-induced glutathione synthesis  Biol Pharm Bull   2005  28(5):779-85  PubMed ID: 15863878   DOI: 10.1248/bpb.28.779
15388  Mario Casolaro, Eugenio Paccagnini, Raniero Mendichi, Yoshihiro Ito  Stimuli-Responsive Polymers Based on l-Phenylalanine Residues:  Protonation Thermodynamics of Free Polymers and Cross-Linked Hydrogels  Macromolecules  2005  38:2460-2468    DOI: 10.1021/ma047652i
15389  Hatao F, Hiki N, Mimura Y, Ogawa T, Kojima J, Mafune K, Hawkins LD, Muroi M, Tanamoto K, Kaminishi M.  The induction of super-resistance using synthetic lipopolysaccharide receptor agonist rescues fatal endotoxemia in rats without excessive immunosuppression  Shock   2005  23(4):365-70  PubMed ID: 15803061   DOI: 10.1097/01.shk.0000158961.01456.b9
2890  Ito T, Morimatsu M, Oonuma T, Shiina T, Kitamura H, Syuto B  Transcriptional regulation of the MAIL gene in LPS-stimulated RAW264 mouse macrophages.  Gene  2004  342:137-43  PubMed ID: 15527973   DOI: 10.1016/j.gene.2004.07.032
2904  Itoh CE, Kizaki T, Hitomi Y, Hanawa T, Kamiya S, Ookawara T, Suzuki K, Izawa T, Saitoh D, Haga S, Ohno H  Down-regulation of beta2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation.  Biochem Biophys Res Commun  2004  322:979-84  PubMed ID: 15336560   DOI: 10.1016/j.bbrc.2004.08.050
3200  Suzuki, Shogo, Nishimaki-Mogami, Tomoko, Tamehiro, Norimasa, Inoue, Kazuhide, Arakawa, Reijiro, Abe-Dohmae, Sumiko, Tanaka, Arowu R, Ueda, Kazumitsu, Yokoyama, Shinji  Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism.  Arterioscler Thromb Vasc Biol  2004  24:519-25  PubMed ID: 14726413   DOI: 10.1161/
3229  Okuhira, Kei-ichiro, Tsujita, Maki, Yamauchi, Yoshio, Abe-Dohmae, Sumiko, Kato, Koichi, Handa, Tetsurou, Yokoyama, Shinji  Potential involvement of dissociated apoA-I in the ABCA1-dependent cellular lipid release by HDL.  J Lipid Res  2004  45:645-52  PubMed ID: 14729855   DOI: 10.1194/jlr.M300257-JLR200
3193  Ban, Hyun Seung, Suzuki, Katsuya, Lim, Soon Sung, Jung, Sang Hoon, Lee, Sanghyun, Ji, Jun, Lee, Hye Seung, Lee, Yeon Sil, Shin, Kuk Hyun, Ohuchi, Kazuo  Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by 2'-hydroxychalcone derivatives in RAW 264.7 cells.  Biochem Pharmacol  2004  67:1549-57  PubMed ID: 15041472   DOI: 10.1016/j.bcp.2003.12.016
3212  Kato, Sawako, Yuzawa, Yukio, Tsuboi, Naotake, Maruyama, Shoichi, Morita, Yoshiki, Matsuguchi, Tetsuya, Matsuo, Seiichi  Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4.  J Am Soc Nephrol  2004  15:1289-99  PubMed ID: 15100369  
2688  Takahashi, Tetsuyuki, Takasuka, Nobuo, Iigo, Masaaki, Baba, Masaki, Nishino, Hoyoku, Tsuda, Hiroyuki, Okuyama, Toru  Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development.  Cancer Sci  2004  95:448-53  PubMed ID: 15132774   DOI: 10.1111/j.1349-7006.2004.tb03230.x
3220  Adachi, Yoshiyuki, Ishii, Takashi, Ikeda, Yoshihiko, Hoshino, Akiyoshi, Tamura, Hiroshi, Aketagawa, Jun, Tanaka, Shigenori, Ohno, Naohito  Characterization of beta-glucan recognition site on C-type lectin, dectin 1.  Infect Immun  2004  72:4159-71  PubMed ID: 15213161   DOI: 10.1128/IAI.72.7.4159-4171.2004
3364  Hatao, Fumihiko, Muroi, Masashi, Hiki, Naoki, Ogawa, Toshihisa, Mimura, Yoshikazu, Kaminishi, Michio, Tanamoto, Ken-ichi  Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein.  J Leukoc Biol  2004  76:904-8  PubMed ID: 15258191   DOI: 10.1189/jlb.0504277
3197  Matsumoto, Masahito, Kogawa, Masakazu, Wada, Seiki, Takayanagi, Hiroshi, Tsujimoto, Masafumi, Katayama, Shigehiro, Hisatake, Koji, Nogi, Yasuhisa  Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1.  J Biol Chem  2004  279:45969-79  PubMed ID: 15304486   DOI: 10.1074/jbc.M408795200
2865  Ikeda, Fumiyo, Nishimura, Riko, Matsubara, Takuma, Tanaka, Sakae, Inoue, Jun-ichiro, Reddy, Sakamuri V, Hata, Kenji, Yamashita, Kenji, Hiraga, Toru, Watanabe, Toshiyuki, Kukita, Toshio, Yoshioka, Katsuji, Rao, Anjana, Yoneda, Toshiyuki  Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation.  J Clin Invest  2004  114:475-84  PubMed ID: 15314684   DOI: 10.1172/JCI19657
18702  Kotanko P, Kramar R, Devrnja D, Paschke E, Voigtländer T, Auinger M, Pagliardini S, Spada M, Demmelbauer K, Lorenz M, Hauser AC, Kofler HJ, Lhotta K, Neyer U, Pronai W, Wallner M, Wieser C, Wiesholzer M, Zodl H, Födinger M, Sunder-Plassmann G.  Results of a nationwide screening for Anderson-Fabry disease among dialysis patients  J Am Soc Nephrol  2004  15(5):1323-9  PubMed ID: 15100373   DOI: 10.1097/01.asn.0000124671.61963.1e
18799  Lee S, Jung SH, Lee YS, Yamada M, Kim BK, Ohuchi K, Shin KH.  Antiinflammatory activity of hyperin from Acanthopanax chiisanensis roots  Arch Pharm Res  2004  27(6):628-32  PubMed ID: 15283465   DOI: 10.1007/BF02980162
3135  Kimura T. et al.  Novel PVA-DNA nanoparticles prepared by ultra high pressure technology for gene delivery.  Materials Science and Engineering C  2004  24:797-801    DOI: 10.1016/j.msec.2004.08.046
6477  Ogasawara T, Katagiri M, Yamamoto A, Hoshi K, Takato T, Nakamura K, Tanaka S, Okayama H, Kawaguchi H.  Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).  J Bone Miner Res  2004  19(7):1128-36  PubMed ID: 15176996   DOI: 10.1359/jbmr.2004.19.7.1128
6737  Naruse M, Otsuka E, Naruse M, Ishihara Y, Miyagawa-Tomita S, Hagiwara H.  Inhibition of osteoclast formation by 3-methylcholanthrene, a ligand for arylhydrocarbon receptor: suppression of osteoclast differentiation factor in osteogenic cells.  Biochem Pharmacol  2004  67(1):119-27  PubMed ID: 14667934   DOI: 10.1016/j.bcp.2003.08.038
13881  Sato A, Keng VW, Yamamoto T, Kasamatsu S, Ban T, Tanaka H, Satoh S, Yamada K, Noguchi T.  Identification and characterization of the hematopoietic cell-specific enhancer-like element of the mouse hex gene  J Biochem  2004  135(2):259-68  PubMed ID: 15047729   DOI: 10.1093/jb/mvh031
14419  Nakamichi K, Inoue S, Takasaki T, Morimoto K, Kurane I.  Rabies virus stimulates nitric oxide production and CXC chemokine ligand 10 expression in macrophages through activation of extracellular signal-regulated kinases 1 and 2  J Virol  2004  78(17):9376-88  PubMed ID: 15308732   DOI: 10.1128/JVI.78.17.9376-9388.2004
17339  Islam S, Hassan F, Mu MM, Ito H, Koide N, Mori I, Yoshida T, Yokochi T.  Piceatannol prevents lipopolysaccharide (LPS)-induced nitric oxide (NO) production and nuclear factor (NF)-kappaB activation by inhibiting IkappaB kinase (IKK)  Microbiol Immunol  2004  48(10):729-36  PubMed ID: 15502405   DOI: 10.1111/j.1348-0421.2004.tb03598.x
17341  Hassan F, Islam S, Koide N, Mu MM, Ito H, Mori I, Yoshida T, Yokochi T.  Role of p38 mitogen-activated protein kinase (MAPK) for vacuole formation in lipopolysaccharide (LPS)-stimulated macrophages  Microbiol Immunol  2004  48(11):807-15  PubMed ID: 15557738   DOI: 10.1111/j.1348-0421.2004.tb03612.x
18901  Hong J, Yamaki K, Ishihara K, Ahn JW, Zee O, Ohuchi K.  Induction of apoptosis of RAW 264.7 cells by the cytostatic macrolide apicularen A  J Pharm Pharmacol  2003  55(9):1299-306  PubMed ID: 14604474   DOI: 10.1211/0022357021639
6705  Murakami Y, Shoji M, Hanazawa S, Tanaka S, Fujisawa S.  Preventive effect of bis-eugenol, a eugenol ortho dimer, on lipopolysaccharide-stimulated nuclear factor kappa B activation and inflammatory cytokine expression in macrophages.  Biochem Pharmacol  2003  66(6):1061-6  PubMed ID: 12963494   DOI: 10.1016/s0006-2952(03)00419-2
15298  Kyoko Watanabe, Yasutaka Azuma, Shinya Shirasu, Michiharu Daito, Kiyoshi Ohura  Alteration of the Expression of A 2 a Adenosine Receptor and Toll-like Receptor 4 in Macrophage Cell Lines.  Japanese Journal of Oral Biology  2003  45:437-444    DOI: 10.2330/joralbiosci1965.45.437
2664  Kizaki, Takako, Suzuki, Kenji, Hitomi, Yoshiaki, Taniguchi, Naoyuki, Saitoh, Daizoh, Watanabe, Kenji, Onoe, Kazunori, Day, Noorbibi K, Good, Robert A, Ohno, Hideki  Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages.  Proc Natl Acad Sci U S A  2002  99:9392-7  PubMed ID: 12089332   DOI: 10.1073/pnas.142206299
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2521  Kinjyo I, Hanada T, Inagaki-Ohara K, Mori H, Aki D, Ohishi M, Yoshida H, Kubo M, Yoshimura A.  SOCS1/JAB is a negative regulator of LPS-induced macrophage activation.  Immunity  2002  17(5):583-91  PubMed ID: 12433365   DOI: 10.1016/s1074-7613(02)00446-6
2529  Yamamoto A, Miyazaki T, Kadono Y, Takayanagi H, Miura T, Nishina H, Katada T, Wakabayashi K, Oda H, Nakamura K, Tanaka S.  Possible involvement of IkappaB kinase 2 and MKK7 in osteoclastogenesis induced by receptor activator of nuclear factor kappaB ligand.  J Bone Miner Res  2002  17(4):612-21  PubMed ID: 11918218   DOI: 10.1359/jbmr.2002.17.4.612
6686  Naraba H, Yokoyama C, Tago N, Murakami M, Kudo I, Fueki M, Oh-Ishi S, Tanabe T.  Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1.  J Biol Chem  2002  277(32):28601-8  PubMed ID: 12034740   DOI: 10.1074/jbc.M203618200
15299  Shibuya A, Wada K, Nakajima A, Saeki M, Katayama K, Mayumi T, Kadowaki T, Niwa H, Kamisaki Y.  Nitration of PPARgamma inhibits ligand-dependent translocation into the nucleus in a macrophage-like cell line, RAW 264  FEBS Lett  2002  525(1-3):43-7  PubMed ID: 12163159   DOI: 10.1016/s0014-5793(02)03059-4
15390  Tsuboi N, Yoshikai Y, Matsuo S, Kikuchi T, Iwami K, Nagai Y, Takeuchi O, Akira S, Matsuguchi T.  Roles of toll-like receptors in C-C chemokine production by renal tubular epithelial cells  J Immunol  2002  169(4):2026-33  PubMed ID: 12165529   DOI: 10.4049/jimmunol.169.4.2026
15391  Shuji Kojima, Risa Kurozumi, Maiko Tuchiya  A New Functional Role of 5,6,7,8-tetrahydrobiopterin (BH4) as an Inhibitor of γ-glutamylcysteine Synthetase (γ-GCS) mRNA Expression  pteridines  2002  13:83-88    DOI: 10.1515/pteridines.2002.13.3.83
15392  Risa Kurozumi, Shuji Kojima  Low-level Nitric Oxide Blunts Oxidant Injury via Up-regulating Glutathione Synthes.  Journal of Health Science  2002  48:140-147    DOI: 10.1248/jhs.48.140
17295  Wakabayashi I, Yasui K, Negoro M.  Diverse effects of ethanol on the pathway of inducible prostaglandin E2 production in macrophages  Prostaglandins Other Lipid Mediat  2002  ;67(1):61-74  PubMed ID: 11789898   DOI: 10.1016/s0090-6980(01)00176-9
2504  Haruta I, Kato Y, Hashimoto E, Minjares C, Kennedy S, Uto H, Yamauchi K, Kobayashi M, Yusa S, Muller U, Hayashi N, Miyazaki T  Association of AIM, a novel apoptosis inhibitory factor, with hepatitis via supporting macrophage survival and enhancing phagocytotic function of macrophages.  J Biol Chem  2001  276:22910-4  PubMed ID: 11294859   DOI: 10.1074/jbc.M100324200
2973  Shiina T, Morimatsu M, Kitamura H, Ito T, Kidou S, Matsubara K, Matsuda Y, Saito M, Syuto B  Genomic organization, chromosomal localization, and promoter analysis of the mouse Mail gene.  Immunogenetics  2001  53:649-55  PubMed ID: 11797098   DOI: 10.1007/s00251-001-0376-x
18566  Takahashi F, Takahashi K, Okazaki T, Maeda K, Ienaga H, Maeda M, Kon S, Uede T, Fukuchi Y.  Role of osteopontin in the pathogenesis of bleomycin-induced pulmonary fibrosis  Am J Respir Cell Mol Biol  2001  24(3):264-71  PubMed ID: 11245625   DOI: 10.1165/ajrcmb.24.3.4293
3777  Arima H, Kihara F, Hirayama F, Uekama K.  Enhancement of gene expression by polyamidoamine dendrimer conjugates with alpha-, beta-, and gamma-cyclodextrins.  Bioconjug Chem  2001  12(4):476-84  PubMed ID: 11459450   DOI: 10.1021/bc000111n
6657  Kikuchi T, Matsuguchi T, Tsuboi N, Mitani A, Tanaka S, Matsuoka M, Yamamoto G, Hishikawa T, Noguchi T, Yoshikai Y.  Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors.  J Immunol  2001  166(5):3574-9  PubMed ID: 11207318   DOI: 10.4049/jimmunol.166.5.3574
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15393  Yokohari K, Yamashita Y, Okada S, Ohya K, Oda S, Hatano M, Mano H, Hirasawa H, Tokuhisa T.  Isoform-dependent interaction of BRDG1 with Tec kinase  Biochem Biophys Res Commun  2001  289(2):414-20  PubMed ID: 11716489   DOI: 10.1006/bbrc.2001.6008
15394  Aramaki Y, Takano S, Tsuchiya S.  Cationic liposomes induce macrophage apoptosis through mitochondrial pathway  Arch Biochem Biophys  2001  392(2):245-50  PubMed ID: 11488598   DOI: 10.1006/abbi.2001.2458
15395  Takano S, Aramaki Y, Tsuchiya S.  Lipoxygenase may be involved in cationic liposome-induced macrophage apoptosis  Biochem Biophys Res Commun  2001  288(1):116-20  PubMed ID: 11594761   DOI: 10.1006/bbrc.2001.5731
15396  Matsumoto M, Hisatake K, Nogi Y, Tsujimoto M.  Regulation of receptor activator of NF-kappaB ligand-induced tartrate-resistant acid phosphatase gene expression by PU.1-interacting protein/interferon regulatory factor-4. Synergism with microphthalmia transcription factor  J Biol Chem  2001  276(35):33086-92  PubMed ID: 11425859   DOI: 10.1074/jbc.M104299200
15397  Matsuguchi T, Musikacharoen T, Johnson TR, Kraft AS, Yoshikai Y.  A novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines  Mol Cell Biol  2001  21(20):6999-7009  PubMed ID: 11564882   DOI: 10.1128/MCB.21.20.6999-7009.2001
15623  Ke X, Terashima M, Nariai Y, Nakashima Y, Nabika T, Tanigawa Y.  Nitric oxide regulates actin reorganization through cGMP and Ca(2+)/calmodulin in RAW 264.7 cells  Biochim Biophys Acta  2001  1539(1-2):101-13  PubMed ID: 11389972   DOI: 10.1016/s0167-4889(01)00090-8
16918  Van Dien M, Takahashi K, Mu MM, Koide N, Sugiyama T, Mori I, Yoshida T, Yokochi T.  Protective effect of wogonin on endotoxin-induced lethal shock in D-galactosamine-sensitized mice  Microbiol Immunol  2001  45(11):751-6  PubMed ID: 11791668   DOI: 10.1111/j.1348-0421.2001.tb01311.x
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3225  Suzuki S, Abe-Dohmae S, Fukutomi T, Ito S, Itoh M, Yokoyama S  Enhancement of the cAMP-induced apolipoprotein-mediated cellular lipid release by calmodulin inhibitors W7 and W5 from RAW 264 mouse macrophage cell line cells.  J Cardiovasc Pharmacol  2000  36:609-16  PubMed ID: 11065221   DOI: 10.1097/00005344-200011000-00010
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3994  Iwahashi H, Takeshita A, Hanazawa S.  Prostaglandin E2 stimulates AP-1-mediated CD14 expression in mouse macrophages via cyclic AMP-dependent protein kinase A.  J Immunol  2000  164(10):5403-8  PubMed ID: 10799905   DOI: 10.4049/jimmunol.164.10.5403
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15403  Hiroyuki Iizuka, Hirofumi Sagara, Shuji Kojima  Modulation of LPS-induced Cell Death by 5,6,7,8-Tetrahydrobiopterin  pteridines  1999  10:202-206    DOI: 10.1515/pteridines.1999.10.4.202
15405  Keiichiro Yoshida, Michio Ono, Hajime Sawada  Lipopolysaccharide-induced vacuoles in macrophages: Their origin is plasma membrane-derived organelles and endoplasmic reticulum, but not lysosomes  Journal of Endotoxin Research  1999  5:127-137    DOI: 10.1177/09680519990050030601
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18030  Hirano S, Ando M.  Fluoride mediates apoptosis in osteosarcoma UMR 106 and its cytotoxicity depends on the pH  Arch Toxicol  1997  72(1):52-8  PubMed ID: 9458191   DOI: 10.1007/s002040050468
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15398  Ohata T, Fukuda K, Takahashi M, Sugimura T, Wakabayashi K.  Suppression of nitric oxide production in lipopolysaccharide-stimulated macrophage cells by omega 3 polyunsaturated fatty acids  Jpn J Cancer Res  1997  88(3):234-7  PubMed ID: 9140106   DOI: 10.1111/j.1349-7006.1997.tb00372.x
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17987  Rie SUZUKI, Toshitaka KIDO, Naoko MIURA, Masahiro YAMAMOTO, Yasuhiro KOMATSU and Kazunori FUKUDA  Inhibitory effects of herbal medicines on nitric oxide production in macrophage and hepatoma cell lines induced by inflammatory stimuli  Journal of Traditional Medicines  1996  13:165-172   
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17952  Joto N, Akimoto T, Someya K, Tohgo A.  Production of tumor necrosis factor induced by synthetic low-toxicity lipid A analog, DT-5461a, is mediated by LPS receptor sites and tyrosine kinase-MAP kinase signaling pathway in murine macrophages  Cell Immunol   1995  160(1):1-7  PubMed ID: 7531115   DOI: 10.1016/0008-8749(95)80002-z
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