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13272
Tanaka KI, Kubota M, Shimoda M, Hayase T, Miyaguchi M, Kobayashi N, Ikeda M, Ishima Y, Kawahara M.
Thioredoxin-albumin fusion protein prevents urban aerosol-induced lung injury via suppressing oxidative stress-related neutrophil extracellular trap formation.
Environ Pollut
2021
PubMed ID: 33065363
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20004
Wada Y, Iyoda M, Matsumoto K, Suzuki T, Tachibana S, Kanazawa N, Honda H.
Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice.
PLoS One
2021
16(1):e0245340
PubMed ID: 33428678
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20009
Li SW, Takahara T, Que W, Fujino M, Guo WZ, Hirano SI, Ye LP, Li XK.
Hydrogen-rich water protects liver injury in nonalcoholic steatohepatitis though HO-1 enhancement via IL-10 and Sirt 1 signaling.
Am J Physiol Gastrointest Liver Physiol
2021
PubMed ID: 33439102
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20023
Madhyastha R, Madhyastha H, Nurrahmah QI, Purbasari B, Maruyama M, Nakajima Y.
MicroRNA 21 Elicits a Pro-inflammatory Response in Macrophages, with Exosomes Functioning as Delivery Vehicles.
Inflammation
2021
PubMed ID: 33501624
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20065
Ma'mag LK, Zintchem AAA, Théodora KK, de Théodore AA, Lauve TY, Frédérich M, Bikobo DSN, Pegnyemb DE.
Antiplasmodial and antileishmanial inhibitory activity of triterpenes and steroidal alkaloid from the leaves of Funtumia elastica (Preuss) Stapf (Apocynaceae).
Fitoterapia
2021
104869
PubMed ID: 33657429
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20088
Nurrahmah QI, Madhyastha R, Madhyastha H, Purbasari B, Maruyama M, Nakajima Y.
Retinoic acid abrogates LPS-induced inflammatory response via negative regulation of NF-kappa B/miR-21 signaling.
Immunopharmacol Immunotoxicol
2021
1-10
PubMed ID: 33757404
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13434
Frederick Ayertey, Ebenezer Ofori-Attah, Stephen Antwi, Michael Amoa-Bosompem, Georgina Djameh, Nathaniel Lartey Lartey, Mistuko Ohashi, Kwadwo Asamoah Kusi, Alfred Ampomah Appiah, Regina Appiah-Opong, Laud Kenneth Okine
Anti-inflammatory activity and mechanism of action of ethanolic leaf extract of Morinda lucida Benth
Journal of Traditional and Complementary Medicine
2020/1/1
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11863
Yamada K, Takizawa S, Ohgaku Y, Asami T, Furuya K, Yamamoto K, Takahashi F, Hamajima C, Inaba C, Endo K, Matsui R, Kitamura H, Tanaka S.
MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages.
Gene
2020
PubMed ID: 31654705
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6906
Shinjyo N, Nakayama H, Ishimaru K, Hikosaka K, Mi-Ichi F, Norose K, Yoshida H.
Hypericum erectum alcoholic extract inhibits Toxoplasma growth and Entamoeba encystation: an exploratory study on the anti-protozoan potential.
J Nat Med
2020
74(1):294-305
PubMed ID: 31728823
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11900
Fujihara Y, Abe T, Asawa Y, Nishizawa S, Saijo H, Hikita A, Hoshi K.
Influence of Damage-Associated Molecular Patterns from Chondrocytes in Tissue-Engineered Cartilage.
Tissue Eng Part A
2020
PubMed ID: 31724485
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12001
Yoshimoto Y, Jo JI, Tabata Y.
Preparation of antibody-immobilized gelatin nanospheres incorporating a molecular beacon to visualize the biological function of macrophages.
Regen Ther
2020
PubMed ID: 31970268
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12006
Kohara Y, Haraguchi R, Kitazawa R, Kitazawa S.
Knockdown of Lrp1 in RAW264 cells inhibits osteoclast differentiation and osteoclast-osteoblast interactions in vitro.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31964526
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12009
Bandow K, Hasegawa H, Tomomura M, Tomomura A.
Caldecrin inhibits lipopolysaccharide-induced pro-inflammatory cytokines and M1 macrophage polarization through the immunoreceptor triggering receptor expressed in myeloid cells-2.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31973822
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12016
Kawakubo M, Tanaka M, Ochi K, Watanabe A, Saka-Tanaka M, Kanamori Y, Yoshioka N, Yamashita S, Goto M, Itoh M, Shirakawa I, Kanai S, Suzuki H, Sawada M, Ito A, Ishigami M, Fujishiro M, Arima H, Ogawa Y, Suganami T.
Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects.
Sci Rep
2020
PubMed ID: 31969650
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12026
Tanaka M, Miyake H, Oka S, Maeda S, Iwasaki K, Mukai T.
Effects of charged lipids on the physicochemical and biological properties of lipid-styrene maleic acid copolymer discoidal particles.
Biochim Biophys Acta Biomembr
2020
PubMed ID: 32004520
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12048
Funakoshi-Tago M, Nonaka Y, Tago K, Takeda M, Ishihara Y, Sakai A, Matsutaka M, Kobata K, Tamura H.
Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2.
Sci Rep
2020
PubMed ID: 32054966
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12058
Phan TKT, Shahbazzadeh F, Kihara T.
Alpha-mangostin reduces mechanical stiffness of various cells.
Hum. Cell
2020
PubMed ID: 32078151
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12092
Kamiya Y, Kikuchi T, Goto H, Okabe I, Takayanagi Y, Suzuki Y, Sawada N, Okabe T, Suzuki Y, Kondo S, Hayashi JI, Mitani A.
IL-35 and RANKL Synergistically Induce Osteoclastogenesis in RAW264 Mouse Monocytic Cells.
Int J Mol Sci
2020
PubMed ID: 32197293
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12110
Uchikawa M, Kato M, Nagata A, Sanada S, Yoshikawa Y, Tsunematsu Y, Sato M, Suzuki T, Hashidume T, Watanabe K, Yoshikawa Y, Miyoshi N.
Elevated levels of proinflammatory volatile metabolites in feces of high fat diet fed KK-Ay mice.
Sci Rep
2020
PubMed ID: 32231228
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12126
Amlabu WE, Antwi CA, Awandare G, Gwira TM.
Elucidating the possible mechanism of action of some pathogen box compounds against Leishmania donovani.
PLoS Negl Trop Dis
2020
PubMed ID: 32275665
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12130
Sanada S, Suzuki T, Nagata A, Hashidume T, Yoshikawa Y, Miyoshi N.
Intestinal microbial metabolite stercobilin involvement in the chronic inflammation of ob/ob mice.
Sci Rep
2020
PubMed ID: 32296105
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12171
Kazunori Sasaki, Yuri Inami, Kenichi Tominaga, Hideo Kigoshi, Takashi Arimura , and Hiroko Isoda
Synthesis of 2-(2-Hydroxyethoxy)-3-hydroxysqualene and Characterization of Its Anti-Inflammatory Effects
BioMed Research International
2020
PubMed ID: 32382581
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10948
Karen Yotsumoto, Terukazu Sanui, Urara Tanaka, Hiroaki Yamato, Rehab Alshargabi, Takanori Shinjo, Yuki Nakao, Yukari Watanabe, Chikako Hayashi, Takaharu Taketomi, Takao Fukuda, Fusanori Nishimura
Amelogenin Downregulates Interferon Gamma-Induced Major Histocompatibility Complex Class II Expression Through Suppression of Euchromatin Formation in the Class II Transactivator Promoter IV Region in Macrophages
Front Immunol
2020
11:709
PubMed ID: 32373130
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12488
Takeda Y, Murata T, Jamsransuren D, Suganuma K, Kazami Y, Batkhuu J, Badral D, Ogawa H.
Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Viruses Including SARS-CoV-2
Viruses
2020
12(7):699
PubMed ID: 32605306
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13012
Kumagai M, Nishikawa K, Mishima T, Yoshida I, Ide M, Watanabe A, Fujita K, Morimoto Y.
Fluorinated Kavalactone Inhibited RANKL-Induced Osteoclast Differentiation of RAW264 Cells.
Biol Pharm Bull
2020
PubMed ID: 32378565
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13036
Tanaka M, Sato A, Kishimoto Y, Mabashi-Asazuma H, Kondo K, Iida K.
Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes.
Nutrients
2020
PubMed ID: 32443660
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13065
Crentsil JA, Yamthe LRT, Anibea BZ, Broni E, Kwofie SK, Tetteh JKA, Osei-Safo D.
Leishmanicidal Potential of Hardwickiic Acid Isolated From Croton sylvaticus.
Front Pharmacol
2020
PubMed ID: 32523532
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13097
Kim Y, Wu L, Park HC, Yang HC.
Reduction of fibrous encapsulation by polyethylene glycol-grafted liposomes containing phosphatidylserine.
Biomed Mater
2020
PubMed ID: 32615550
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13137
Kawata R, Oda S, Koya Y, Kajiyama H, Yokoi T.
Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production.
Toxicology
2020
PubMed ID: 32739513
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13139
Kawai K, Egami Y, Nishigaki A, Araki N.
Rab35 Targeting to the Plasma Membrane Is Dependent on the C-terminal Polybasic Cluster.
Acta Histochem Cytochem
2020
PubMed ID: 32873993
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13146
Ertunc N, Sato C, Kitajima K.
Sialic acid sulfation is induced by the antibiotic treatment in mammalian cells.
Biosci Biotechnol Biochem
2020
PubMed ID: 32752946
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13150
Totani H, Shinjo K, Suzuki M, Katsushima K, Mase S, Masaki A, Ito A, Ri M, Kusumoto S, Komatsu H, Ishida T, Inagaki H, Iida S, Kondo Y.
Autocrine HGF/c-Met signaling pathway confers aggressiveness in lymph node adult T-cell leukemia/lymphoma.
Oncogene
2020
PubMed ID: 32747750
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13168
Mikami A, Ogita T, Namai F, Shigemori S, Sato T, Shimosato T.
Oral administration of Flavonifractor plautii attenuates inflammatory responses in obese adipose tissue.
Mol Biol Rep
2020
PubMed ID: 32808115
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13180
Wada S, Kanzaki H, Katsumata Y, Yamaguchi Y, Narimiya T, Attucks OC, Nakamura Y, Tomonari H.
Bach1 Inhibition Suppresses Osteoclastogenesis via Reduction of the Signaling via Reactive Oxygen Species by Reinforced Antioxidation.
Front Cell Dev Biol
2020
PubMed ID: 32850850
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13258
Takeuchi T, Horimoto Y, Oyama M, Nakatani S, Kobata K, Tamura M, Arata Y, Hatanaka T.
Osteoclast Differentiation Is Suppressed by Increased O-GlcNAcylation Due to Thiamet G Treatment.
Biol Pharm Bull
2020
PubMed ID: 32999159
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13294
Nishigaki C, Nakayama M, Miyata H.
Cell physiological responses of RAW264 macrophage cells to a 50-Hz magnetic field.
Int J Radiat Biol
2020
PubMed ID: 33052723
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13298
Yang X, Sasano T, Ebana Y, Takeuchi JK, Ihara K, Yamazoe M, Furukawa T.
Functional Role of the L396R Mutation of Tks5 Identified by an Exome-Wide Association Study in Atrial Fibrillation.
Circ J
2020
PubMed ID: 33087629
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13324
Yahiro K, Ogura K, Goto Y, Iyoda S, Kobayashi T, Takeuchi H, Ohnishi M, Moss J.
Subtilase cytotoxin induces a novel form of Lipocalin 2, which promotes Shiga-toxigenic Escherichia coli survival.
Sci Rep
2020
PubMed ID: 33144618
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13341
Matur M, Madhyastha H, Shruthi TS, Madhyastha R, Srinivas SP, Navya PN, Daima HK.
Engineering bioactive surfaces on nanoparticles and their biological interactions.
Sci Rep
2020
PubMed ID: 33184324
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13373
Kuriyama T, Fukuma Y, Imashiro C, Kabayama K, Kurashina Y, Takemura K.
Detachment of RAW264.7 macrophages from a culture dish using ultrasound excited by a Langevin transducer.
J Biosci Bioeng
2020
PubMed ID: 33250410
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13464
Sugiyama T, Hobro AJ, Pavillon N, Umakoshi T, Verma P, Smith N.
Label-free Raman mapping of saturated and unsaturated fatty acid uptake, storage, and return toward baseline levels in macrophages
Analyst
2020
Dec 21
PubMed ID: 33346264
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13492
Masanori HASHIMOTO, Haruaki KITAGAWA, Yusuke TAKAHASHI, Mikako HAYASHI, Satoshi IMAZATO
Cytotoxicity of S-PRG Fillers: Direct Exposure of Fillers and Eluates from the Fillers to RAW264 Cells
Nano Biomedicine
2020
12:3-10
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13545
Quan H, Kim Y, Wu L, Park HC, Yang HC.
Modulation of Macrophage Polarization by Phospholipids on the Surface of Titanium
Molecules
2020
25(11):2700
PubMed ID: 32532146
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13614
Kuramoto M, Kawashima N, Tazawa K, Nara K, Fujii M, Noda S, Hashimoto K, Nozaki K, Okiji T.
Mineral trioxide aggregate suppresses pro-inflammatory cytokine expression via the calcineurin/nuclear factor of activated T cells/early growth response 2 pathway in lipopolysaccharide-stimulated macrophages
Int Endod J
2020
53(12):1653-1665
PubMed ID: 32767860
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13633
Lu DZ, Dong W, Feng XJ, Chen H, Liu JJ, Wang H, Zang LY, Qi MC.
CaMKII(δ) regulates osteoclastogenesis through ERK, JNK, and p38 MAPKs and CREB signalling pathway
Mol Cell Endocrinol
2020
508:110791
PubMed ID: 32173349
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13639
Nishiguchi A, Taguchi T.
Development of an immunosuppressive camouflage-coating platform with nanocellulose and cell membrane vesicles
J Biomater Sci Polym Ed
2020
31(15):1912-1924
PubMed ID: 32538290
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13643
Nishiguchi A, Taguchi T.
Sustained-immunostimulatory nanocellulose scaffold to enhance vaccine efficacy
J Biomed Mater Res A
2020
108(5):1159-1170
PubMed ID: 31990447
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11167
Chaweewannakorn W, Ariyoshi W, Okinaga T, Fujita Y, Maki K, Nishihara T.
Ameloblastin attenuates RANKL-mediated osteoclastogenesis by suppressing activation of nuclear factor of activated T-cell cytoplasmic 1 (NFATc1).
J. Cell. Physiol.
2019
234(2):1745-175
PubMed ID: 30105896
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11173
Madhyastha R, Madhyastha H, Pengjam Y, Nurrahmah QI, Nakajima Y, Maruyama M.
The pivotal role of microRNA-21 in osteoclastogenesis inhibition by anthracycline glycoside aloin.
J Nat Med
2019
73(1):59-66
PubMed ID: 30116953
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11279
Sun S, Li K, Xiao L, Lei Z, Zhang Z.
Characterization of polysaccharide from Helicteres angustifolia L. and its immunomodulatory activities on macrophages RAW264.7.
Biomed. Pharmacother.
2019
PubMed ID: 30396084
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11335
Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Ando K, Tanimoto K.
The effect of mesenchymal stem cells on osteoclast precursor cell differentiation.
J Oral Sci
2019
PubMed ID: 30541990
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11361
Islam Z, Inui T, Ishibashi O.
Gpr137b is an orphan G-protein-coupled receptor associated with M2 macrophage polarization.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 30595385
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11380
Nemoto R, Fujieda K, Hiruta Y, Hishida M, Ayano E, Maitani Y, Nagase K, Kanazawa H.
Liposomes with temperature-responsive reversible surface properties.
Colloids Surf B Biointerfaces
2019
PubMed ID: 30641302
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11396
Yoshinaga N, Uchida S, Naito M, Osada K, Cabral H, Kataoka K.
Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection.
Biomaterials
2019
PubMed ID: 30669016
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11383
Manabe Y, Hirata T, Sugawara T.
Inhibitory Effect of Carotenoids on Ligand-induced Lipid Raft Translocation of Immunoreceptors.
J Oleo Sci
2019
PubMed ID: 30651415
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11389
Wang W, Nakashima KI, Hirai T, Inoue M.
Anti-inflammatory effects of naturally occurring retinoid X receptor agonists isolated from Sophora tonkinensis Gagnep. via retinoid X receptor/liver X receptor heterodimers.
J Nat Med
2019
PubMed ID: 30656541
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11457
Takahashi S, Yoshida M, Watanabe MM, Isoda H.
Anti-Inflammatory Effects of Aurantiochytrium limacinum 4W-1b Ethanol Extract on Murine Macrophage RAW264 Cells.
Biomed Res Int
2019
PubMed ID: 30809537
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11437
Yanagihara Y, Inoue K, Saeki N, Sawada Y, Yoshida S, Lee J, Iimura T, Imai Y.
Zscan10 suppresses osteoclast differentiation by regulating expression of Haptoglobin.
Bone
2019
PubMed ID: 30771488
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11454
Antwi CA, Amisigo CM, Adjimani JP, Gwira TM.
In vitro activity and mode of action of phenolic compounds on Leishmania donovani.
PLoS Negl Trop Dis
2019
PubMed ID: 30802252
|
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11477
Zhang T, Ono K, Tsutsuki H, Ihara H, Islam W, Akaike T, Sawa T.
Enhanced Cellular Polysulfides Negatively Regulate TLR4 Signaling and Mitigate Lethal Endotoxin Shock.
Cell Chem Biol
2019
PubMed ID: 30853417
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5357
Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.
AUTACs: Cargo-Specific Degraders Using Selective Autophagy.
Mol Cell
2019
76(5):797-810
PubMed ID: 31606272
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11498
Narita Y, Shimizu K, Ikemoto K, Uchino R, Kosugi M, Maess MB, Magata Y, Oku N, Ogawa M.
Macrophage-targeted, enzyme-triggered fluorescence switch-on system for detection of embolism-vulnerable atherosclerotic plaques.
J Control Release
2019
PubMed ID: 30936020
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11508
Saito H, Tanaka T, Sugahara M, Tanaka S, Fukui K, Wakashima T, Nangaku M.
Inhibition of prolyl hydroxylase domain (PHD) by JTZ-951 reduces obesity-related diseases in the liver, white adipose tissue, and kidney in mice with a high-fat diet.
Lab. Invest.
2019
PubMed ID: 30952940
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11539
Suzuka H, Mimura A, Inaoka Y, Murase K.
Magnetic Nanoparticles in Macrophages and Cancer Cells Exhibit Different Signal Behavior on Magnetic Particle Imaging.
J Nanosci Nanotechnol
2019
PubMed ID: 31039837
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11604
Miyazaki Y, Iwaihara Y, Bak J, Nakano H, Takeuchi S, Takeuchi H, Matsui T, Tachikawa D.
The cooperative induction of macrophage activation by fucoidan derived from Cladosiphon okamuranus and β-glucan derived from Saccharomyces cerevisiae.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 31221482
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11608
Tsuhako R, Yoshida H, Sugita C, Kurokawa M.
Naringenin suppresses neutrophil infiltration into adipose tissue in high-fat diet-induced obese mice.
J Nat Med
2019
PubMed ID: 31218550
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11617
Takeuchi T, Koinuma S, Yokosawa H, Arata Y.
An Approach for the Identification of Proteins Modified with ISG15.
Methods Mol. Biol.
2019
PubMed ID: 31256383
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11704
Miori Tanaka, Ayako Sugama, Kanako Sumi, Kozue Shimizu, Yoshimi Kishimoto, Kazuo Kondo, Kaoruko Iida
Gallic acid regulates adipocyte hypertrophy and suppresses inflammatory gene expression induced by the paracrine interaction between adipocytes and macrophages in vitro and in vivo
Nutrition Research
2019
73:58-66
PubMed ID: 31841748
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11736
Wang X, Batubara I, Yamauchi K, Mitsunaga T.
Identification and structure-activity relationship (SAR) of chemical constituents from Daemonorops draco (Willd.) Blume and selected commercial flavonoids on anti-osteoclastogenesis activity.
Fitoterapia
2019
PubMed ID: 31376421
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11757
Manabe Y, Takii Y, Sugawara T.
Siphonaxanthin, a carotenoid from green algae, suppresses advanced glycation end product-induced inflammatory responses.
J Nat Med
2019
PubMed ID: 31432315
|
|
11772
Okuda-Hanafusa C, Uchio R, Fuwa A, Kawasaki K, Muroyama K, Yamamoto Y, Murosaki S.
Turmeronol A and turmeronol B from Curcuma longa prevent inflammatory mediator production by lipopolysaccharide-stimulated RAW264.7 macrophages, partially via reduced NF-κB signaling.
Food Funct
2019
PubMed ID: 31454011
|
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11780
Tan H, Zhao C, Zhu Q, Katakura Y, Tanaka H, Ohnuki K, Shimizu K.
Ursolic Acid Isolated from the Leaves of Loquat ( Eriobotrya japonica) Inhibited Osteoclast Differentiation through Targeting Exportin 5.
J. Agric. Food Chem.
2019
PubMed ID: 30827108
|
|
11793
Mizuno Y, Taguchi T.
Growth factor-free, angiogenic hydrogel based on hydrophobically modified Alaska pollock gelatin.
J Tissue Eng Regen Med
2019
PubMed ID: 31503405
|
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11801
Ueta M, Takaoka K, Yamamura M, Maeda H, Tamaoka J, Nakano Y, Noguchi K, Kishimoto H.
Effects of TGF‑β1 on the migration and morphology of RAW264.7 cells in vitro.
Mol Med Rep
2019
PubMed ID: 31545488
|
|
11810
Ara T, Koide M, Kitamura H, Sogawa N.
Effects of shokyo (Zingiberis Rhizoma) and kankyo (Zingiberis Processum Rhizoma) on prostaglandin E2 production in lipopolysaccharide-treated mouse macrophage RAW264.7 cells.
PeerJ
2019
PubMed ID: 31576251
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11873
Ju N, Shimamura M, Hayashi H, Ikeda Y, Yoshida S, Nakamura A, Morishita R, Rakugi H, Nakagami H.
Preventative effects of the partial RANKL peptide MHP1-AcN in a mouse model of imiquimod-induced psoriasis.
Sci Rep
2019
PubMed ID: 31659208
|
|
6944
Yo S, Hamamura K, Mishima Y, Hamajima K, Mori H, Furukawa K, Kondo H, Tanaka K, Sato T, Miyazawa K, Goto S, Togari A.
Deficiency of GD3 Synthase in Mice Resulting in the Attenuation of Bone Loss with Aging.
Int J Mol Sci
2019
20(11):2825
PubMed ID: 31185614
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9468
Kazuyo Fujita, Masaharu Somiya, Shun'ichi Kuroda, Shuji Hinuma
Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes
Biochem Biophys Res Commun
2019
510(1):184-190
PubMed ID: 30678809
|
|
10512
Sayumi Yamada et al
Anti-Inflammatory and Antimicrobial Activities of Aqueous Extracts of Wild Mushrooms from Japan
International Journal of Medicinal Mushrooms
2019
21:469-486
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10763
Ahmed Elkhateeb, Mona El-Shabrawy, Rehab F. Abdel-Rahman, Mona M. Marzouk, Ahmed H. El-Desoky, El-Sayed S. Abdel-Hameed & Sameh R. Hussein
LC-MS-based metabolomic profiling of Lepidium coronopus water extract, anti-inflammatory and analgesic activities, and chemosystematic significance
Medicinal Chemistry Research
2019
28:505–514
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10848
X.YangaZ.Lei, Y.YuaL.Xiao, D.Cheng, Z.Zhang
Phytochemical characteristics of callus suspension culture of Helicteres angustifolia L. and its in vitro antioxidant, antidiabetic and immunomodulatory activities
South African Journal of Botany
2019
121:178-185
|
|
11886
Ali MFZ, Ohta T, Ido A, Miura C, Miura T.
The Dipterose of Black Soldier Fly (Hermetia illucens) Induces Innate Immune Response through Toll-Like Receptor Pathway in Mouse Macrophage RAW264.7 Cells.
Biomolecules
2019
PubMed ID: 31683715
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|
11908
Pavillon N, Smith NI.
Immune cell type, cell activation, and single cell heterogeneity revealed by label-free optical methods.
Sci Rep
2019
PubMed ID: 31745140
|
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11914
Shimakura H, Gen-Nagata F, Haritani M, Furusaki K, Kato Y, Yamashita-Kawanishi N, LE DT, Tsuzuki M, Tohya Y, Kyuwa S, Saito H, Horimoto T, Onodera T, Haga T.
Inactivation of human norovirus and its surrogate by the disinfectant consisting of calcium hydrogen carbonate mesoscopic crystals.
FEMS Microbiol. Lett.
2019
PubMed ID: 31758686
|
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11948
Yamashiro T, Yasujima T, Ohta K, Inoue K, Yuasa H.
Identification of the amino acid residue responsible for the myricetin sensitivity of human proton-coupled folate transporter.
Sci Rep
2019
PubMed ID: 31792273
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12316
Kitazawa R, Kinto-Shibahara S, Haraguchi R, Kohara Y, Kitazawa S.
Activation of protein kinase C accelerates murine osteoclastogenesis partly via transactivation of RANK gene through functional AP-1 responsive element in RANK gene promoter
Biochem Biophys Res Commun
2019
515(2):268-274
PubMed ID: 31146918
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|
12336
Sakakura A, Pauze M, Namiki A, Funakoshi-Tago M, Tamura H, Hanaya K, Higashibayashi S, Sugai T.
Chemoenzymatic synthesis of hydroxytyrosol monoesters and their suppression effect on nitric oxide production stimulated by lipopolysaccharides
Biosci Biotechnol Biochem
2019
83(2):185-191
PubMed ID: 30319060
|
|
12555
Islam Z, Horikawa A, Inui T, Ishibashi O.
Datasets of microarray analysis to identify Gpr137b-dependent interleukin-4-responsive genes in the mouse macrophage cell line RAW264
Data Brief
2019
23:103669
PubMed ID: 31372377
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12556
Saiki P, Kawano Y, Nakajima Y, Van Griensven LJLD, Miyazaki K.
Reporters Derived from RAW 264.7 for Anti-Inflammation Screening of Natural Products
Int J Mol Sci
2019
20(18):4620
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12557
Kono Y, Gogatsubo S, Ohba T, Fujita T.
Enhanced macrophage delivery to the colon using magnetic lipoplexes with a magnetic field
Drug Deliv
2019
26(1):935-943
PubMed ID: 31530198
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12558
Pan H, Bian X, Yang S, He Y, Yang X, Liu Y.
The cell line ontology-based representation, integration and analysis of cell lines used in China
BMC Bioinformatics
2019
20(Suppl 5):179
PubMed ID: 31272367
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12559
Li F, Kitajima S, Kohno S, Yoshida A, Tange S, Sasaki S, Okada N, Nishimoto Y, Muranaka H, Nagatani N, Suzuki M, Masuda S, Thai TC, Nishiuchi T, Tanaka T, Barbie DA, Mukaida N, Takahashi C.
Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion
Cancer Res
2019
79(15):3903-3915
PubMed ID: 31189648
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12978
Kojima C, Narita Y, Nakajima Y, Morimoto N, Yoshikawa T, Takahashi N, Handa A, Waku T, Tanaka N.
Modulation of Cell Adhesion and Differentiation on Collagen Gels by the Addition of the Ovalbumin Secretory Signal Peptide.
ACS Biomater Sci Eng
2019
PubMed ID: 33405701
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10342
Fujihara Y, Hikita A, Takato T, Hoshi K.
Roles of macrophage migration inhibitory factor in cartilage tissue engineering.
J. Cell. Physiol.
2018
233:1490-1499
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10432
Tokuyama-Nakai S, Kimura H, Ishihara T, Jisaka M, Yokota K.
In Vitro Anti-inflammatory and Antioxidant Activities of 3,5,4'-Trihydroxy-6,7-Methylenedioxyflavone-O-Glycosides and Their Aglycone from Leaves of Polygonum tinctorium Lour.
Appl. Biochem. Biotechnol.
2018
184:414-431
PubMed ID: 28721651
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10557
Elfeky M, Yoneshiro T, Okamatsu-Ogura Y, Kimura K.
Adiponectin suppression of late inflammatory mediator, HMGB1-induced cytokine expression in RAW264 macrophage cells.
J. Biochem.
2018
163:143-153
PubMed ID: 29048484
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10569
Yamaguchi Y, Kanzaki H, Katsumata Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.
Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation.
J. Cell. Mol. Med.
2018
22:1138-1147
PubMed ID: 29063666
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10614
Stockler-Pinto MB, Soulage CO, Borges NA, Cardozo LFMF, Dolenga CJ, Nakao LS, Pecoits-Filho R, Fouque D, Mafra D.
From bench to the hemodialysis clinic: protein-bound uremic toxins modulate NF-κB/Nrf2 expression.
Int Urol Nephrol
2018
50:347-354
PubMed ID: 29151180
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10645
Nagahara H, Seno T, Yamamoto A, Obayashi H, Inoue T, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y.
Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.
Biochem. Biophys. Res. Commun.
2018
495:1901-1907
PubMed ID: 29225172
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10696
Kumagai M, Watanabe A, Yoshida I, Mishima T, Nakamura M, Nishikawa K, Morimoto Y.
Evaluation of Aculeatin and Toddaculin Isolated from Toddalia asiatica as Anti-inflammatory Agents in LPS-Stimulated RAW264 Macrophages.
Biol. Pharm. Bull.
2018
41:132-137
PubMed ID: 29311475
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10708
Kon R, Tsubota Y, Minami M, Kato S, Matsunaga Y, Kimura H, Murakami Y, Fujikawa T, Sakurai R, Tomimoto R, Machida Y, Ikarashi N, Sugiyama K.
CPT-11-Induced Delayed Diarrhea Develops via Reduced Aquaporin-3 Expression in the Colon.
Int J Mol Sci
2018
19:
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10711
Egami Y, Araki N.
Transient recruitment of M-Ras GTPase to phagocytic cups in RAW264 macrophages during FcγR-mediated phagocytosis.
Microscopy (Oxf)
2018
67:68-74
PubMed ID: 29340604
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10714
Tsukayama I, Toda K, Takeda Y, Mega T, Tanaka M, Kawakami Y, Takahashi Y, Kimoto M, Yamamoto K, Miki Y, Murakami M, Suzuki-Yamamoto T.
Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway.
J Clin Biochem Nutr
2018
62:139-147
PubMed ID: 29610553
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10782
Miyashita T, Minami K, Ito M, Koizumi R, Sagane Y, Watanabe T, Niwa K.
Emu Oil Reduces LPS-Induced Production of Nitric Oxide and TNF-α but not Phagocytosis in RAW 264 Macrophages.
J Oleo Sci
2018
67:471-477
PubMed ID: 29526880
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10790
El-Desoky AH, Abdel-Rahman RF, Ahmed OK, El-Beltagi HS, Hattori M.
Anti-inflammatory and antioxidant activities of naringin isolated from Carissa carandas L.: In vitro and in vivo evidence.
Phytomedicine
2018
42:126-134
PubMed ID: 29655678
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10799
Kawai C, Yamauchi A, Kuribayashi F.
Monoclonal antibody 7D5 recognizes the R147 epitope on the gp91phox , phagocyte flavocytochrome b558 large subunit.
Microbiol. Immunol.
2018
62:269-280
PubMed ID: 29573449
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11027
Miyake T, Miyake T, Sakaguchi M, Nankai H, Nakazawa T, Morishita R.
Prevention of Asthma Exacerbation in a Mouse Model by Simultaneous Inhibition of NF-kB and STAT6 Activation Using a Chimeric Decoy Strategy
Mol Ther Nucleic Acids
2018
10:159-169
PubMed ID: 29499930
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11198
Ikebuchi Y, Aoki S, Honma M, Hayashi M, Sugamori Y, Khan M, Kariya Y, Kato G, Tabata Y, Penninger JM, Udagawa N, Aoki K, Suzuki H.
Coupling of bone resorption and formation by RANKL reverse signalling.
Nature
2018
561(7722):195-200
PubMed ID: 30185903
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4050
Mukai Y, Yamanishi R.
Retinol but not retinoic acid can enhance the glutathione level, in a manner similar to β-carotene, in a murine cultured macrophage cell line.
Food Sci Nutr
2018
PubMed ID: 30258608
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11098
Ali MFZ, Yasin IA, Ohta T, Hashizume A, Ido A, Takahashi T, Miura C, Miura T.
The silkrose of Bombyx mori effectively prevents vibriosis in penaeid prawns via the activation of innate immunity.
Sci Rep
2018
8(1):8836
PubMed ID: 29892000
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11116
Tasaka T, Kuwada E, Izuchi Y, Nishigawa R, Yamada H, Unuma H, Tokunaga K, Hayakawa A, Go A, Go K, Uto Y.
Concentration-dependent Activation of Inflammatory/Anti-inflammatory Functions of Macrophages by Hydrolyzed Whey Protein.
Anticancer Res.
2018
38(7):4299-4304
PubMed ID: 29970565
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11122
Sakoda M, Kaneko M, Ohta S, Qi P, Ichimura S, Yatomi Y, Ito T.
Injectable Hemostat Composed of a Polyphosphate-Conjugated Hyaluronan Hydrogel.
Biomacromolecules
2018
19(8):3280-3290
PubMed ID: 29985587
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11186
Kawasaki K, Okuda-Hanafusa C, Aoyagi M, Taoka K, Yamamoto N, Muroyama K, Murosaki S, Yamamoto Y.
Inhibitory effect of the compounds from the water extract of Curcuma longa on the production of PGE2 and NO in a macrophage cell line stimulated by LPS.
Biosci. Biotechnol. Biochem.
2018
82(12):2109-2117
PubMed ID: 30146952
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11200
Odkhuu E, Komatsu T, Koide N, Naiki Y, Takeuchi K, Tanaka Y, Tsolmongyn B, Jambalganiin U, Morita N, Yoshida T, Gotoh B, Yokochi T.
Sendai virus C protein limits NO production in infected RAW264.7 macrophages.
Innate Immun
2018
24(7):430-438
PubMed ID: 30189760
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11074
Tsukamoto H, Takeuchi S, Kubota K, Kobayashi Y, Kozakai S, Ukai I, Shichiku A, Okubo M, Numasaki M, Kanemitsu Y, Matsumoto Y, Nochi T, Watanabe K, Aso H, Tomioka Y.
Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKK?-IRF3 axis activation.
J. Biol. Chem.
2018
293(26):10186-10201
PubMed ID: 29760187
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11112
Niino T, Tago K, Yasuda D, Takahashi K, Mashino T, Tamura H, Funakoshi-Tago M.
A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis.
Biochem. Pharmacol.
2018
155:182-197
PubMed ID: 29940171
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11249
Kamiya T, Tanimoto Y, Fujii N, Negishi T, Suzuki T, Hatano T, Arimoto-Kobayashi S.
2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae.
Food Chem. Toxicol.
2018
PubMed ID: 30316843
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11493
Katsumata Y, Kanzaki H, Honda Y, Tanaka T, Yamaguchi Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y.
Single Local Injection of Epigallocatechin Gallate-Modified Gelatin Attenuates Bone Resorption and Orthodontic Tooth Movement in Mice.
Polymers (Basel)
2018
10(12)
PubMed ID: 30961309
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11349
Sugiyama Y, Hiraiwa Y, Hagiya Y, Nakajima M, Tanaka T, Ogura SI.
5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW 264.7 macrophages.
BMC Immunol.
2018
PubMed ID: 30567499
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4441
Seisho Azuma, Yoshinobu Murakami, Eiko Azuma, Kimiye Baba, Masahiko Taniguchi
Anti-inflammatory effects of flavonoids in Citrus jabara fruit peels
Trends in Immunotherapy
2018
2
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Quan H, Kim Y, Park HC, Yang HC.
Effects of phosphatidylserine-containing supported lipid bilayers on the polarization of macrophages.
J Biomed Mater Res A
2018
PubMed ID: 29781181
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4325
Hoshi K, Yamazaki T, Yoshikawa C, Tsugawa W, Ikebukuro K, Sode K.
Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production.
Int J Nanomedicine
2018
PubMed ID: 30122920
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4326
Saiki P, Nakajima Y, Van Griensven LJLD, Miyazaki K.
Real-time monitoring of IL-6 and IL-10 reporter expression for anti-inflammation activity in live RAW 264.7 cells.
Biochem. Biophys. Res. Commun.
2018
PubMed ID: 30301531
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4327
Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Tanimoto K.
Dynamic imaging of the effect of mesenchymal stem cells on osteoclast precursor cell chemotaxis for bone defects in the mouse skull.
J Dent Sci
2018
PubMed ID: 30895145
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4328
Sumi K, Abe T, Kunimatsu R, Oki N, Tsuka Y, Awada T, Nakajima K, Ando K, Tanimoto K.
The effect of mesenchymal stem cells on chemotaxis of osteoclast precursor cells.
J Oral Sci
2018
PubMed ID: 29925706
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4329
Kajita T, Ariyoshi W, Okinaga T, Mitsugi S, Tominaga K, Nishihara T.
Mechanisms involved in enhancement of osteoclast formation by activin-A.
J. Cell. Biochem.
2018
PubMed ID: 29737562
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4330
Sakamoto T, Ohashi W, Tomita K, Hattori K, Matsuda N, Hattori Y.
Anti-inflammatory properties of cilostazol: Its interruption of DNA binding activity of NF-κB from the Toll-like receptor signaling pathways.
Int. Immunopharmacol.
2018
PubMed ID: 30005227
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4331
El-Beih AA, El-Desoky AH, Al-Hammady MA, Elshamy AI, Hegazy MF, Kato H, Tsukamoto S.
New inhibitors of RANKL-induced Osteoclastogenesis from the marine sponge Siphonochalina siphonella.
Fitoterapia
2018
PubMed ID: 29729401
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4332
Tanaka M, Kishimoto Y, Sasaki M, Sato A, Kamiya T, Kondo K, Iida K.
Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways.
Oxid Med Cell Longev
2018
PubMed ID: 30533177
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4333
Kawabata K, Baba N, Sakano T, Hamano Y, Taira S, Tamura A, Baba S, Natsume M, Ishii T, Murakami S, Ohigashi H.
Functional properties of anti-inflammatory substances from quercetin-treated Bifidobacterium adolescentis.
Biosci. Biotechnol. Biochem.
2018
PubMed ID: 29165050
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4334
Fukai E, Sato H, Watanabe M, Nakae D, Totsuka Y.
Establishment of an in vivo simulating co-culture assay platform for genotoxicity of multi-walled carbon nanotubes.
Cancer Sci.
2018
PubMed ID: 29444368
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4335
Hussain Z, Uyama T, Kawai K, Binte Mustafiz SS, Tsuboi K, Araki N, Ueda N.
Phosphatidylserine-stimulated production of N-acyl-phosphatidylethanolamines by Ca2+-dependent N-acyltransferase.
Biochim Biophys Acta Mol Cell Biol Lipids
2018
PubMed ID: 29447909
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4336
Takahashi S, Sakamaki M, Ferdousi F, Yoshida M, Demura M, Watanabe MM, Isoda H.
Ethanol Extract of Aurantiochytrium mangrovei 18W-13a Strain Possesses Anti-inflammatory Effects on Murine Macrophage RAW264 Cells.
Front Physiol
2018
PubMed ID: 30319432
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4496
Su YW, Chim SM, Zhou L, Hassanshahi M, Chung R, Fan C, Song Y, Foster BK, Prestidge CA, Peymanfar Y, Tang Q, Butler LM, Gronthos S, Chen D, Xie Y, Chen L, Zhou XF, Xu J, Xian CJ.
Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats.
Bone
2018
116:232-247
PubMed ID: 30125729
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4497
Kuroda C, Ueda K, Haniu H, Ishida H, Okano S, Takizawa T, Sobajima A, Kamanaka T, Yoshida K, Okamoto M, Tsukahara T, Matsuda Y, Aoki K, Kato H, Saito N.
Different aggregation and shape characteristics of carbon materials affect biological responses in RAW264 cells.
Int J Nanomedicine
2018
13:6079-6088
PubMed ID: 30323595
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4498
Momozane T, Kawamura T, Itoh Y, Sanosaka M, Sasaki T, Kanzaki R, Ose N, Funaki S, Shintani Y, Minami M, Okumura M, Takemori H.
Carnosol suppresses interleukin-6 production in mouse lungs injured by ischemia-reperfusion operation and in RAW264.7 macrophages treated with lipopolysaccharide.
Biochem. Cell Biol.
2018
96(6):769-776
PubMed ID: 29958095
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4499
Choodej S, Pudhom K, Mitsunaga T.
Inhibition of TNF-α-Induced Inflammation by Sesquiterpene Lactones from Saussurea lappa and Semi-Synthetic Analogues.
Planta Med.
2018
84(5):329-335
PubMed ID: 28962049
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7036
Komiya C, Tanaka M, Tsuchiya K, Shimazu N, Mori K, Furuke S, Miyachi Y, Shiba K, Yamaguchi S, Ikeda K, Ochi K, Nakabayashi K, Hata KI, Itoh M, Suganami T, Ogawa Y.
Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis.
Sci Rep
2017
7:44754
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9723
Iwazaki K, Tanaka T, Hozumi Y, Okada M, Tsuchiya R, Iseki K, Topham MK, Kawamae K, Takagi M, Goto K.
DGKζ Downregulation Enhances Osteoclast Differentiation and Bone Resorption Activity Under Inflammatory Conditions.
J. Cell. Physiol.
2017
232:617-624
PubMed ID: 27312515
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9944
Kanzaki H, Shinohara F, Itohiya K, Yamaguchi Y, Katsumata Y, Matsuzawa M, Fukaya S, Miyamoto Y, Wada S, Nakamura Y.
RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice.
FASEB J.
2017
31:781-792
PubMed ID: 27836987
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9964
Shirasugi M, Nishioka K, Yamamoto T, Nakaya T, Kanamura N.
Normal human gingival fibroblasts undergo cytostasis and apoptosis after long-term exposure to butyric acid.
Biochem. Biophys. Res. Commun.
2017
482:1122-1128
PubMed ID: 27914813
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10001
Quan H, Park HC, Kim Y, Yang HC.
Modulation of the anti-inflammatory effects of phosphatidylserine-containing liposomes by PEGylation.
J Biomed Mater Res A
2017
105:1479-1486
PubMed ID: 27998010
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10074
Takano A, Fukuda T, Shinjo T, Iwashita M, Matsuzaki E, Yamamichi K, Takeshita M, Sanui T, Nishimura F.
Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation.
Metab. Clin. Exp.
2017
69:157-170
PubMed ID: 28285646
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10085
Ariyoshi W, Okinaga T, Chaweewannakorn W, Akifusa S, Nisihara T.
Mechanisms involved in enhancement of matrix metalloproteinase-9 expression in macrophages by interleukin-33.
J. Cell. Physiol.
2017
232:3481-3495
PubMed ID: 28105703
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10122
Taniguchi M, Ochiai A, Toyoda R, Sato T, Saitoh E, Kato T, Tanaka T.
Effects of arginine and leucine substitutions on anti-endotoxic activities and mechanisms of action of cationic and amphipathic antimicrobial octadecapeptide from rice α-amylase.
J. Pept. Sci.
2017
23:252-260
PubMed ID: 28185358
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10165
Takeuchi T, Sugimoto A, Imazato N, Tamura M, Nakatani S, Kobata K, Arata Y.
Glucosamine Suppresses Osteoclast Differentiation through the Modulation of Glycosylation Including O-GlcNAcylation.
Biol. Pharm. Bull.
2017
40:352-356
PubMed ID: 28250278
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10169
Zhang J, Hiromoto S, Yamazaki T, Huang H, Jia G, Li H, Yuan G.
Macrophage phagocytosis of biomedical Mg alloy degradation products prepared by electrochemical method.
Mater Sci Eng C Mater Biol Appl
2017
75:1178-1183
PubMed ID: 28415404
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10190
Ichimura K, Shimizu T, Matsumoto A, Hirai S, Yokoyama E, Takeuchi H, Yahiro K, Noda M.
Nitric oxide-enhanced Shiga toxin production was regulated by Fur and RecA in enterohemorrhagic Escherichia coli O157.
Microbiologyopen
2017
6:
PubMed ID: 28294553
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10215
Yamagata Y, Tomioka H, Sakamoto K, Sato K, Harada H, Ikeda T, Kayamori K.
CD163-Positive Macrophages Within the Tumor Stroma Are Associated With Lymphangiogenesis and Lymph Node Metastasis in Oral Squamous Cell Carcinoma.
J. Oral Maxillofac. Surg.
2017
75:2144-2153
PubMed ID: 28399391
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10230
Hashiguchi A, Hitachi K, Zhu W, Tian J, Tsuchida K, Komatsu S.
Mung bean (Vigna radiata (L.)) coat extract modulates macrophage functions to enhance antigen presentation: A proteomic study.
J Proteomics
2017
161:26-37
PubMed ID: 28373035
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10285
Fereig RM, Kuroda Y, Terkawi MA, Mahmoud ME, Nishikawa Y.
Immunization with Toxoplasma gondii peroxiredoxin 1 induces protective immunity against toxoplasmosis in mice.
PLoS ONE
2017
12:e0176324
PubMed ID: 28448521
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10288
Kato T, Toyooka T, Ibuki Y, Masuda S, Watanabe M, Totsuka Y.
Effect of physicochemical character differences on the genotoxic potency of kaolin.
Genes Environ
2017
39:12
PubMed ID: 28469735
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10335
Wu S, Yano S, Chen J, Hisanaga A, Sakao K, He X, He J, Hou DX.
Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-Induced Inflammation through Dual Modulation of Inflammatory and Antioxidant Mediators.
J. Agric. Food Chem.
2017
65:5133-5141
PubMed ID: 28573848
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10380
Murata K, Motomura Y, Tanaka T, Kanno S, Yano T, Onimaru M, Shimoyama A, Nishio H, Sakai Y, Oh-Hora M, Hara H, Fukase K, Takada H, Masuda S, Ohga S, Yamasaki S, Hara T.
Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease.
Clin. Exp. Immunol.
2017
190:54-67
PubMed ID: 28640392
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10551
Saiki P, Kawano Y, Van Griensven LJLD, Miyazaki K.
The anti-inflammatory effect of Agaricus brasiliensis is partly due to its linoleic acid content.
Food Funct
2017
8:4150-4158
PubMed ID: 29022634
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10704
Hanagata N, Li X, Chen MH, Li J, Hattori S.
Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities.
Int J Nanomedicine
2017
13:43-62
PubMed ID: 29317815
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10915
Effect of Particle Size of Gold Nanoparticles on Matrix Metalloprotease Inhibition, Cytotoxicity and Genotoxicity
Journal of Biomaterials and Tissue Engineering,
2017
7, 139-146
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10949
Effect of 50-Hz Sinusoidal Magnetic Field on the Production of Superoxide Anion and the Expression of Heat-shock Protein 70 in RAW264 Cells
International Journal of Chemistry
2017
9
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4526
Yusuke Hiraku, Yoshihiro Nishikawa, Ning Ma, Tahmina Afroza, Kosuke Mizobuchi, Ryo Ishiyama, Yuta Matsunaga, Takamichi Ichinose, Shosuke Kawanishi, Mariko Murata
Nitrative DNA damage induced by carbon-black nanoparticles in macrophages and lung epithelial cells
Mutation Research/Genetic Toxicology and Environmental Mutagenesis
2017
818, 7-16
PubMed ID: 28477879
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6471
Horigome S, Yoshida I, Ito S, Inohana S, Fushimi K, Nagai T, Yamaguchi A, Fujita K, Satoyama T, Katsuda SI, Suzuki S, Watai M, Hirose N, Mitsue T, Shirakawa H, Komai M.
Inhibitory effects of Kaempferia parviflora extract on monocyte adhesion and cellular reactive oxygen species production in human umbilical vein endothelial cells.
Eur J Nutr
2017
56(3):949-964
PubMed ID: 26704713
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10050
Ha-Eun Yang, Yongjia Li, Akira Nishimura, Huei-Fen Jheng, Ana Yuliana, Ryuji Kitano-Ohue, Wataru Nomura, Nobuyuki Takahashi, Chu-Sook Kim, Rina Yu, Nahoko Kitamura, Si-Bum Park, Shigenobu Kishino, Jun Ogawa, Teruo Kawada, Tsuyoshi Goto
Synthesized Enone Fatty Acids Resembling Metabolites From Gut Microbiota Suppress Macrophage-Mediated Inflammation in Adipocytes
Mol Nutr Food Res
2017
Oct;61(10)
PubMed ID: 28544341
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10076
Yusuke Kono, Taketo Nakai, Hitomi Taguchi, Takuya Fujita
Development of Magnetic Anionic Liposome/Atelocollagen Complexes for Efficient Magnetic Drug Targeting
Drug Deliv
2017
24(1):1740-1749
PubMed ID: 29141461
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7077
Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake K, Takatsu K.
Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice.
Sci Rep
2016
6:23097
PubMed ID: 26975571
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7094
Ryohei Hamaguchi, Yukihiro Kuroda
A Novel Biomarker for Cellular Toxicity and Phospholipid Accumulation by Cationic Amphiphilic Drugs.
Chromatography
2016
37:35-38
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7119
Taniguchi M, Ochiai A, Matsushima K, Tajima K, Kato T, Saitoh E, Tanaka T.
Endotoxin-neutralizing activity and mechanism of action of a cationic α-helical antimicrobial octadecapeptide derived from α-amylase of rice.
Peptides
2016
75:101-8
PubMed ID: 26643956
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7148
Ohta T, Kusano K, Ido A, Miura C, Miura T.
Silkrose: A novel acidic polysaccharide from the silkmoth that can stimulate the innate immune response.
Carbohydr Polym
2016
136:995-1001
PubMed ID: 26572439
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7157
Higuchi H, Shoji T, Murase Y, Iijima S, Nishijima K.
Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264.
Biosci. Biotechnol. Biochem.
2016
80:501-9
PubMed ID: 26540411
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7230
Takayama S, Hashimoto K, Kokubu E, Taniguchi M, Tajima K, Ochiai A, Saitoh E, Saito A, Ishihara K, Kato T.
Inhibitory effects of a novel cationic dodecapeptide [CL(14-25)] derived from cyanate lyase of rice on endotoxic activities of LPSs from Escherichia coli and periodontopathic Aggregatibacter actinomycetemcomitans.
Microb. Pathog.
2016
94:2-11
PubMed ID: 26318142
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Hashimoto M, Sasaki J, Imazato S.
Investigation of the cytotoxicity of aluminum oxide nanoparticles and nanowires and their localization in L929 fibroblasts and RAW264 macrophages.
J. Biomed. Mater. Res. Part B Appl. Biomater.
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Lu Y, Cao L, Egami Y, Kawai K, Araki N.
Cofilin contributes to phagocytosis of IgG-opsonized particles but not non-opsonized particles in RAW264 macrophages.
Microscopy (Oxf)
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Takeuchi T, Nagasaka M, Shimizu M, Tamura M, Arata Y.
N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation.
Bone Rep
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Kuno M, Li G, Moriura Y, Hino Y, Kawawaki J, Sakai H.
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Pflugers Arch.
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Wada T, Sunaga H, Miyata K, Shirasaki H, Uchiyama Y, Shimba S.
Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression.
J. Biol. Chem.
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Pengjam Y, Madhyastha H, Madhyastha R, Yamaguchi Y, Nakajima Y, Maruyama M.
NF-κB pathway inhibition by anthrocyclic glycoside aloin is key event in preventing osteoclastogenesis in RAW264.7 cells.
Phytomedicine
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Sugiyama K, Muroi M, Kinoshita M, Hamada O, Minai Y, Sugita-Konishi Y, Kamata Y, Tanamoto K.
NF-κB activation via MyD88-dependent Toll-like receptor signaling is inhibited by trichothecene mycotoxin deoxynivalenol.
J Toxicol Sci
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Nakabayashi H, Aoyama S, Kawahara M, Nagamune T.
Differentiation signalobody: Demonstration of antigen-dependent osteoclast differentiation from a progenitor cell line.
J. Biosci. Bioeng.
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Furuoka M, Ozaki K, Sadatomi D, Mamiya S, Yonezawa T, Tanimura S, Takeda K.
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Elfeky M, Kaede R, Okamatsu-Ogura Y, Kimura K.
Adiponectin Inhibits LPS-Induced HMGB1 Release through an AMP Kinase and Heme Oxygenase-1-Dependent Pathway in RAW 264 Macrophage Cells.
Mediators Inflamm.
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Kure A, Nakagawa K, Kondo M, Kato S, Kimura F, Watanabe A, Shoji N, Hatanaka S, Tsushida T, Miyazawa T.
Metabolic Fate of Luteolin in Rats: Its Relationship to Anti-inflammatory Effect.
J. Agric. Food Chem.
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Zhang J, Hiromoto S, Yamazaki T, Niu J, Huang H, Jia G, Li H, Ding W, Yuan G.
Effect of macrophages on in vitro corrosion behavior of magnesium alloy.
J Biomed Mater Res A
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Sunarso , Toita R, Tsuru K, Ishikawa K.
A superhydrophilic titanium implant functionalized by ozone gas modulates bone marrow cell and macrophage responses.
J Mater Sci Mater Med
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Arikawa M, Kakinuma Y, Noguchi T, Todaka H, Sato T.
Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation.
Eur. J. Pharmacol.
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Kanzaki H, Shinohara F, Suzuki M, Wada S, Miyamoto Y, Yamaguchi Y, Katsumata Y, Makihira S, Kawai T, Taubman MA, Nakamura Y.
A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma.
Sci Rep
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Moriwaki S, Into T, Suzuki K, Miyauchi M, Takata T, Shibayama K, Niida S.
γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.
Sci Rep
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Yamawaki T, Ito E, Mukai A, Ueno M, Yamada J, Sotozono C, Kinoshita S, Hamuro J.
The Ingenious Interactions Between Macrophages and Functionally Plastic Retinal Pigment Epithelium Cells.
Invest. Ophthalmol. Vis. Sci.
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Domon H, Oda M, Maekawa T, Nagai K, Takeda W, Terao Y.
Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis.
Sci Rep
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6:38013
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Kejuan Li, Xi Yang, Xuansheng Hu, Chao Han, Zhongfang Lei, Zhenya Zhang
In vitro antioxidant, immunomodulatory and anticancer activities of two fractions of aqueous extract from Helicteres angustifolia L. root
Journal of the Taiwan Institute of Chemical Engineers
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61:75-82
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Clinical Evaluation of Novel Natural Polysaccharides Sacran as a Skincare Material for Atopic Dermatitis Patients
Journal of Cosmetics, Dermatological Sciences and Applications
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6, 9-18
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Isolation and Biochemical Characterization of Mucus Proteins in Japanese Bunching Onion (Allium fistulosum) Green Leaves
Food Science and Technology Research
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Yusuke Kono, Ayu Iwasaki, Kenta Matsuoka, Takuya Fujita
Effect of Mechanical Agitation on Cationic Liposome Transport Across an Unstirred Water Layer in Caco-2 Cells
Biol Pharm Bull
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39(8):1293-9
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Goto T, Naknukool S, Yoshitake R, Hanafusa Y, Tokiwa S, Li Y, Sakamoto T, Nitta T, Kim M, Takahashi N, Yu R, Daiyasu H, Seno S, Matsuda H, Kawada T.
Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes
Cytokinec
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Hashimoto M, Kawai K, Kawakami H, Imazato S.
Matrix metalloproteases inhibition and biocompatibility of gold and platinum nanoparticles
J Biomed Mater Res A
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Ichikawa N, Yamashita K, Funakoshi T, Ichihara S, Fukai M, Ogura M, Kobayashi N, Zaitsu M, Yoshida T, Shibasaki S, Koshizuka Y, Tsunetoshi Y, Sato M, Einama T, Ozaki M, Umezawa K, Suzuki T, Todo S.
Novel anti-inflammatory agent 3-[(dodecylthiocarbonyl)-methyl]-glutarimide ameliorates murine models of inflammatory bowel disease
Inflamm Res
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65(3):245-60
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Hayashida Y, Ikeda Y, Sawada K, Kawai K, Kato T, Kakehi Y, Araki N.
Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor
Int J Cancer
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139(3):700-11
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Nagahara H, Yamamoto A, Seno T, Obayashi H, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y.
Allograft inflammatory factor-1 in the pathogenesis of bleomycin-induced acute lung injury
Biosci Trends
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Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa TO, Kataoka Y, Yamamura K.
Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo.
Sci Rep
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Sawada Y, Sakamoto Y, Toh M, Ohara N, Hatanaka Y, Naka A, Kishimoto Y, Kondo K, Iida K.
Milk-derived peptide Val-Pro-Pro (VPP) inhibits obesity-induced adipose inflammation via an angiotensin-converting enzyme (ACE) dependent cascade.
Mol Nutr Food Res
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59:2502-10
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Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.
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Tang L, Okamoto S, Shiuchi T, Toda C, Takagi K, Sato T, Saito K, Yokota S, Minokoshi Y.
Sympathetic Nerve Activity Maintains an Anti-Inflammatory State in Adipose Tissue in Male Mice by Inhibiting TNF-α Gene Expression in Macrophages.
Endocrinology
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Hashimoto M, Sasaki JI, Yamaguchi S, Kawai K, Kawakami H, Iwasaki Y, Imazato S.
Gold Nanoparticles Inhibit Matrix Metalloproteases without Cytotoxicity.
J. Dent. Res.
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Suzuki N, Takimoto K, Kawashima N.
Cathepsin K Inhibitor Regulates Inflammation and Bone Destruction in Experimentally Induced Rat Periapical Lesions.
J Endod
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Miyazaki T, Miyauchi S, Anada T, Tawada A, Suzuki O.
Chondroitin Sulfate-E Binds to Both Osteoactivin and Integrin αVβ3 and Inhibits Osteoclast Differentiation.
J. Cell. Biochem.
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Takeuchi T, Shimakawa G, Tamura M, Yokosawa H, Arata Y.
ISG15 regulates RANKL-induced osteoclastogenic differentiation of RAW264 cells.
Biol. Pharm. Bull.
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Hashimoto M, Imazato S.
Cytotoxic and genotoxic characterization of aluminum and silicon oxide nanoparticles in macrophages.
Dent Mater
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Kawabata K, Kato Y, Sakano T, Baba N, Hagiwara K, Tamura A, Baba S, Natsume M, Ohigashi H.
Effects of phytochemicals on in vitro anti-inflammatory activity of Bifidobacterium adolescentis.
Biosci. Biotechnol. Biochem.
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Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M.
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Am. J. Physiol. Renal Physiol.
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Kim YI, Mohri S, Hirai S, Lin S, Goto T, Ohyane C, Sakamoto T, Takahashi H, Shibata D, Takahashi N, Kawada T.
Tomato extract suppresses the production of proinflammatory mediators induced by interaction between adipocytes and macrophages.
Biosci. Biotechnol. Biochem.
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79:82-7
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Taniguchi M, Ochiai A, Takahashi K, Nakamichi S, Nomoto T, Saitoh E, Kato T, Tanaka T.
Antimicrobial activity and mechanism of action of a novel cationic α-helical octadecapeptide derived from α-amylase of rice.
Biopolymers
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104:73-83
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F Shima, T Akagi, M Shudo, E Mochizuki, T Tsuda, S Kuwabata M Akashi
Interaction between living cells and polymeric particles: potential application of ionic liquid for evaluating the cellular uptake of biodegradable polymeric particles composed of poly(amino acid).
Polymer Journal
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Uto T, Tung NH, Taniyama R, Miyanowaki T, Morinaga O, Shoyama Y.
Anti-inflammatory Activity of Constituents Isolated from Aerial Part of Angelica acutiloba Kitagawa.
Phytother Res
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29(12):1956-63
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Yao-Tong Lai, Seiichi Ohta, Kazuki Akamatsu, Shin-Ichi Nakao, Yasuyuki Sakai, Taichi Ito
Size-dependent Interaction of Cells and Hemoglobin-Albumin Based Oxygen Carriers Prepared Using the SPG Membrane Emulsification Technique
Biotechnol Prog .
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31(6):1676-84
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Akihiko Nagao, Takashi Maoka, Hiroshi Ono, Eiichi Kotake-Nara, Miyuki Kobayashi, Mie Tomita
A 3-hydroxy β-End Group in Xanthophylls Is Preferentially Oxidized to a 3-oxo ε-End Group in Mammals
J Lipid Res
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56(2):449-62
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Masayori Hagimori, Naoko Mizuyama, Yoshinori Tominaga, Takahiro Mukai,Hideo Saji
A low-molecular-weight fluorescent sensor with Zn2+ dependent bathochromic shift of emission wavelength and its imaging in living cells
Dyes and Pigments
2015
113:205-209
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Shiro Kato, Yuki Masuda, Morichika Konishi, Tadao Oikawa
Enantioselective analysis of D- and L-amino acids from mouse macrophages using high performance liquid chromatography
J Pharm Biomed Anal
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116:101-4
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Takashi Ando, Takayuki Komatsu, Yoshikazu Naiki, Takashi Yokochi, Daisuke Watanabe, Naoki Koide
Pretreatment of LPS inhibits IFN-β-induced STAT1 phosphorylation through SOCS3 induced by LPS
Biomed Pharmacother
2015
76:1-5
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12252
Yoshiro Kato, Hideki Kamiya, Naoki Koide, Erdenezaya Odkhuu, Takayuki Komatsu, Atsuko Watarai, Masaki Kondo, Koichi Kato, Jiro Nakamura, Takashi Yokochi
Irbesartan attenuates production of high-mobility group box 1 in response to lipopolysaccharide via downregulation of interferon-β production
Int Immunopharmacol
2015
26(1):97-102
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Shusong Wu, Xi He, Xiaosong Wu, Si Qin, Jianhua He, Shirui Zhang, De-Xing Hou
Inhibitory effects of blue honeysuckle (Lonicera caerulea L) on adjuvant-induced arthritis in rats: Crosstalk of anti-inflammatory and antioxidant effects
J Functional Foods
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Itoh T, Tsuchida A, Muramatsu Y, Ninomiya M, Ando M, Tsukamasa Y, Koketsu M.
Antimicrobial and anti-inflammatory properties of nostocionone isolated from Nostoc commune Vauch and its derivatives against Propionibacterium acnes.
Anaerobe
2014
27:56-63
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Yamasaki T, Ariyoshi W, Okinaga T, Adachi Y, Hosokawa R, Mochizuki S, Sakurai K, Nishihara T.
The dectin 1 agonist curdlan regulates osteoclastogenesis by inhibiting nuclear factor of activated T cells cytoplasmic 1 (NFATc1) through Syk kinase.
J Biol Chem
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289(27):19191-203
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Nakazato R, Takarada T, Watanabe T, Nguyen BT, Ikeno S, Hinoi E, Yoneda Y.
Constitutive and functional expression of runt-related transcription factor-2 by microglial cells.
Neurochem Int
2014
74:24-35
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Erdenezaya Odkhuu, Takayuki Komatsu, Yoshikazu Naiki, Naoki Koide, Takashi Yokochi
Sendai Virus C Protein Inhibits Lipopolysaccharide-Induced Nitric Oxide Production Through Impairing Interferon-β Signaling
Int Immunopharmacol
2014
23 (1), 267-72
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Ran Zhao, Masayoshi Kamon, Kazuichi Sakamoto
(–)-Epigallocatechingallate Interferes RANKL/RANK Signal Pathway and Induces Apoptosis during Osteoclastogenesis in RAW264 Cell
Food and Nutrition Sciences
2014
5:107-116
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Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo
Responses of RAW264.7 Macrophages to Water-Dispersible Gold and Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds
J Biomed Mater Res A
2014
102(6):1838-49
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Miki Tadaishi, Yoriko Nishide, Yuko Tousen, Marlena C Kruger, Yoshiko Ishimi
Cooperative Effects of Soy Isoflavones and Carotenoids on Osteoclast Formation
J Clin Biochem Nutr
2014
54(2):109-15
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Tada R, Koide Y, Yamamuro M, Tanaka R, Hidaka A, Nagao K, Aramaki Y.
Maleylated-BSA suppresses lipopolysaccharide-induced IL-6 production by activating the ERK-signaling pathway in murine RAW264.7 cells
Int Immunopharmacol
2014
19(1):5-9
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7584
T. Atsumi, A. Iwashita, I. Ohtsuka, N. Kakiuchi, Y. Sasaki, M. Mikage, K. Toriizuka
Effects of Atractylodis Lanceae Rhizoma on inflammatory mediator production from the RAW264 macrophage cell line
J Traditional Medicines
2013
30:124-131
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Takeshi KAWAHARA, Daichi NAKAYAMA, Keisuke TODA, Shyuichiro INAGAKI, Katsumi TANAKA, Hisako YASUI
Suppressive Effect of Wild Saccharomyces cerevisiae and Saccharomyces paradoxus Strains on Ige Production by Mouse Spleen Cells
Food Sci. Technol. Res
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19 (6), 1019 – 1027
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Ito S, Tanaka Y, Nishio N, Thanasegaran S, Isobe K.
Establishment of self-renewable GM-CSF-dependent immature macrophages in vitro from murine bone marrow.
PLoS One
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Horibe K, Nakamichi Y, Uehara S, Nakamura M, Koide M, Kobayashi Y, Takahashi N, Udagawa N.
Roles of cathelicidin-related antimicrobial peptide in murine osteoclastogenesis.
Immunology
2013
140(3):344-51
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Etoh T, Kim YP, Ohsaki A, Komiyama K, Hayashi M.
Inhibitory effect of erythraline on Toll-like receptor signaling pathway in RAW264.7 cells.
Biol Pharm Bull
2013
36(8):1363-9
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Etoh T, Kim YP, Tanaka H, Hayashi M.
Anti-inflammatory effect of berkeleyacetal C through the inhibition of interleukin-1 receptor-associated kinase-4 activity.
Eur J Pharmacol
2013
698(1-3):435-43
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9096
Kyoko Ueda, Ryoko Kawabata, Takashi Irie, Yoshiaki Nakai, Yukinobu Tohya, Takemasa Sakaguchi
Inactivation of Pathogenic Viruses by Plant-Derived Tannins: Strong Effects of Extracts From Persimmon (Diospyros Kaki) on a Broad Range of Viruses
PLoS One
2013
8 (1), e55343
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Hiroki Ishikawa, Naoki Awano, Toshie Fukui, Hiraku Sasaki, Shigeru Kyuwa
The Protective Effects of Lactoferrin Against Murine Norovirus Infection Through Inhibition of Both Viral Attachment and Replication
Biochem Biophys Res Commun
2013
434 (4), 791-6
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Akari Ishisaka, Kyuichi Kawabata, Satomi Miki, Yuko Shiba, Shoko Minekawa, Tomomi Nishikawa, Rie Mukai, Junji Terao, Yoshichika Kawai
Mitochondrial Dysfunction Leads to Deconjugation of Quercetin Glucuronides in Inflammatory Macrophages
PLoS One
2013
8 (11), e80843
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Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo
Micromorphological Cellular Responses of MC3T3-E1 and RAW264.7 After Exposure to Water-Dispersible Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds
Dent Mater J
2013
32(5):725-33
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Hirohiko Okamura, Di Yang, Kaya Yoshida, Tatsuji Haneji
Protein Phosphatase 2A Cα Is Involved in Osteoclastogenesis by Regulating RANKL and OPG Expression in Osteoblasts
FEBS Lett
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587(1):48-53
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Kazuhiro Nakaya, Makoto Ayaori, Harumi Uto-Kondo, Grace Megumi Sotherden, Takafumi Nishida, Haruka Katamoto, Yuko Miura, Shunichi Takiguchi, Emi Yakushiji, Maki Iizuka, Masatsune Ogura, Makoto Sasaki, Makiko Yogo, Tomohiro Komatsu, Takeshi Adachi, Chizuko Maruyama, Katsunori Ikewaki
Overexpression of stearoyl-coenzyme A desaturase 1 in macrophages promotes reverse cholesterol transport
Biochim Biophys Acta
2013
1831(8):1402-11
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Suzuki S, Nishio SI, Ishii H, Sekido T, Takeshige K, Ohkubo Y, Hiwatashi D, Takeda T, Komatsu M.
Possible roles of the AP-1 site in the cytosolic T3 binding protein promoter and insights into its physiological significance.
Horm Metab Res
2013
45(7):501-6
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Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Masahiro Iijima, Kazuhiko Endo
Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Masahiro Iijima, Kazuhiko Endo
Journal of Biomaterials and Tissue Engineering
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Funakoshi T, Yamashita K, Ichikawa N, Fukai M, Suzuki T, Goto R, Oura T, Kobayashi N, Katsurada T, Ichihara S, Ozaki M, Umezawa K, Todo S.
A novel NF-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice.
J Crohns Colitis
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Takano K, Sato K, Negishi Y, Aramaki Y.
Involvement of actin cytoskeleton in macrophage apoptosis induced by cationic liposomes.
Arch. Biochem. Biophys.
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518:89-94
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Takahashi K, Sugiyama T, Tokoro S, Neri P, Mori H.
Inhibition of interferon-γ-induced nitric oxide production by 10-hydroxy-trans-2-decenoic acid through inhibition of interferon regulatory factor-8 induction.
Cell. Immunol.
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Uto T, Morinaga O, Tanaka H, Shoyama Y.
Analysis of the synergistic effect of glycyrrhizin and other constituents in licorice extract on lipopolysaccharide-induced nitric oxide production using knock-out extract.
Biochem. Biophys. Res. Commun.
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Nakagawa S, Arai Y, Kishida T, Hiraoka N, Tsuchida S, Inoue H, Sakai R, Mazda O, Kubo T.
Lansoprazole inhibits nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells.
Inflammation
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Uto T, Qin GW, Morinaga O, Shoyama Y.
17-Hydroxy-jolkinolide B, a diterpenoid from Euphorbia fischeriana, inhibits inflammatory mediators but activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine macrophages.
Int. Immunopharmacol.
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Uchida M, Oyanagi E, Kremenik MJ, Sasaki J, Yano H.
Interferon-beta, but not tumor necrosis factor-alpha, production in response to poly I:C is maintained despite exhaustive exercise in mice.
J Physiol Sci
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Sugiyama T, Takahashi K, Tokoro S, Gotou T, Neri P, Mori H.
Inhibitory effect of 10-hydroxy-trans-2-decenoic acid on LPS-induced IL-6 production via reducing IκB-ζ expression.
Innate Immun
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Honda H, Nagai Y, Matsunaga T, Saitoh S, Akashi-Takamura S, Hayashi H, Fujii I, Miyake K, Muraguchi A, Takatsu K.
Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner.
J Leukoc Biol
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Echigo R, Shimohata N, Karatsu K, Yano F, Kayasuga-Kariya Y, Fujisawa A, Ohto T, Kita Y, Nakamura M, Suzuki S, Mochizuki M, Shimizu T, Chung UI, Sasaki N.
Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage.
J Transl Med
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Takarada T, Takarada-Iemata M, Takahata Y, Yamada D, Yamamoto T, Nakamura Y, Hinoi E, Yoneda Y.
Osteoclastogenesis is negatively regulated by D-serine produced by osteoblasts.
J Cell Physiol
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Hiroyasu Tsutsuki, Kinnosuke Yahiro, Kotaro Suzuki, Akira Suto, Kohei Ogura, Sayaka Nagasawa, Hideshi Ihara, Takeshi Shimizu, Hiroshi Nakajima, Joel Moss, Masatoshi Noda
Subtilase Cytotoxin Enhances Escherichia Coli Survival in Macrophages by Suppression of Nitric Oxide Production Through the Inhibition of NF-κB Activation
Infect Immun
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Cryptococcus neoformans suppresses the activation of bone marrow-derived dendritic cells stimulated with its own DNA, but not with DNA from other fungi.
FEMS Immunol. Med. Microbiol.
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A genome-wide microarray highlights the antiinflammatory genes targeted by oolong tea theasinensin A in macrophages.
Nutr Cancer
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Sakamoto T, Yamaguchi Y, Goto T, Takahashi N, Kawada T.
An in vitro analysis system using a fluorescence protein reporter for evaluating anti-inflammatory effects in macrophages.
Biosci. Biotechnol. Biochem.
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Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.
Biochem. Biophys. Res. Commun.
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Fujimoto A, Akifusa S, Hirofuji T, Yamashita Y.
Involvement of suppressor of cytokine signaling-1 in globular adiponectin-induced granulocyte colony-stimulating factor in RAW 264 cell.
Mol. Immunol.
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Abiko Y, Miura T, Phuc BH, Shinkai Y, Kumagai Y.
Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole.
Toxicol. Appl. Pharmacol.
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Haque A, Noman AS, Koide N, Odkhuu E, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T.
An ADP ribosylation factor-GTPase activating protein negatively regulates the production of proinflammatory mediators in response to lipopolysaccharide.
Cancer Immunol. Immunother.
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Egusa H, Doi M, Saeki M, Fukuyasu S, Akashi Y, Yokota Y, Yatani H, Kamisaki Y.
The small molecule harmine regulates NFATc1 and Id2 expression in osteoclast progenitor cells.
Bone
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Akagi T, Shima F, Akashi M.
Intracellular degradation and distribution of protein-encapsulated amphiphilic poly(amino acid) nanoparticles.
Biomaterials
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Inhibitory effects of herbal alkaloids on the tumor necrosis factor-α and nitric oxide production in lipopolysaccharide-stimulated RAW264 macrophages.
Chem. Pharm. Bull.
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Kurio N, Shimo T, Fukazawa T, Takaoka M, Okui T, Hassan NM, Honami T, Hatakeyama S, Ikeda M, Naomoto Y, Sasaki A.
Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo.
Exp. Cell Res.
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Involvement of lipid rafts in macrophage apoptosis induced by cationic liposomes.
Arch. Biochem. Biophys.
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Ichioka M, Suganami T, Tsuda N, Shirakawa I, Hirata Y, Satoh-Asahara N, Shimoda Y, Tanaka M, Kim-Saijo M, Miyamoto Y, Kamei Y, Sata M, Ogawa Y.
Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans.
Diabetes
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60:819-26
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Haque A, Koide N, Iftakhar-E-Khuda I, Noman AS, Odkhuu E, Badamtseren B, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Flavopiridol inhibits lipopolysaccharide-induced TNF-α production through inactivation of nuclear factor-κB and mitogen-activated protein kinases in the MyD88-dependent pathway.
Microbiol. Immunol.
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Miyazaki T, Miyauchi S, Anada T, Imaizumi H, Suzuki O.
Evaluation of osteoclastic resorption activity using calcium phosphate coating combined with labeled polyanion.
Anal. Biochem.
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Yonezawa T, Hasegawa S, Asai M, Ninomiya T, Sasaki T, Cha BY, Teruya T, Ozawa H, Yagasaki K, Nagai K, Woo JT.
Harmine, a β-carboline alkaloid, inhibits osteoclast differentiation and bone resorption in vitro and in vivo.
Eur. J. Pharmacol.
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Diacylglycerol kinase alpha regulates globular adiponectin-induced reactive oxygen species.
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Fukata N, Uchida K, Kusuda T, Koyabu M, Miyoshi H, Fukui T, Matsushita M, Nishio A, Tabata Y, Okazaki K.
The effective therapy of cyclosporine A with drug delivery system in experimental colitis.
J Drug Target
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Tumurkhuu G, Koide N, Hiwasa T, Ookoshi M, Dagvadorj J, Abu Shadat Mohammod Noman, Iftakhar-E-Khuda I, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock.
Innate Immun
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Shikama Y, Kuroishi T, Nagai Y, Iwakura Y, Shimauchi H, Takada H, Sugawara S, Endo Y.
Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).
Innate Immun
2011
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Hou DX, Masuzaki S, Tanigawa S, Hashimoto F, Chen J, Sogo T, Fujii M.
Oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (LPS)-activated mouse macrophages: structure-activity relationship and molecular mechanisms.
J. Agric. Food Chem.
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Prostaglandin E? signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors.
Gastroenterology
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Repeated oral administration of a squeezed ginger (Zingiber officinale) extract augmented the serum corticosterone level and had anti-inflammatory properties.
Biosci. Biotechnol. Biochem.
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Sakagami H, Zhou L, Kawano M, Thet MM, Tanaka S, Machino M, Amano S, Kuroshita R, Watanabe S, Chu Q, Wang QT, Kanamoto T, Terakubo S, Nakashima H, Sekine K, Shirataki Y, Zhang CH, Uesawa Y, Mohri K, Kitajima M, Oizumi H, Oizumi T.
Multiple biological complex of alkaline extract of the leaves of Sasa senanensis Rehder.
In Vivo
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Lee JW, Mase N, Yonezawa T, Seo HJ, Jeon WB, Cha BY, Nagai K, Woo JT.
Palmatine attenuates osteoclast differentiation and function through inhibition of receptor activator of nuclear factor-κb ligand expression in osteoblast cells.
Biol. Pharm. Bull.
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Okui T, Shimo T, Fukazawa T, Kurio N, Hassan NM, Honami T, Takaoka M, Naomoto Y, Sasaki A.
Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction.
Mol. Cancer Ther.
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Shikama Y, Nagai Y, Okada S, Oizumi T, Shimauchi H, Sugawara S, Endo Y.
Pro-IL-1β accumulation in macrophages by alendronate and its prevention by clodronate.
Toxicol. Lett.
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Yoshikawa K, Kokudo N, Hashimoto T, Yamamoto K, Inose T, Kimura T.
Novel phthalide compounds from Sparassis crispa (Hanabiratake), Hanabiratakelide A-C, exhibiting anti-cancer related activity.
Biol. Pharm. Bull.
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Nakatsuka R, Nozaki T, Shinohara M, Ohura K.
Dilazep decreases lipopolysaccharide-induced nitric oxide and TNF-alpha synthesis in RAW 264 cells.
J. Pharmacol. Sci.
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Yano H, Uchida M, Nakai R, Ishida K, Kato Y, Kawanishi N, Shiva D.
Exhaustive exercise reduces TNF-α and IFN-α production in response to R-848 via toll-like receptor 7 in mice.
Eur. J. Appl. Physiol.
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Shadat NM, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Retinoblastoma protein-interacting zinc finger 1 (RIZ1) regulates the proliferation of monocytic leukemia cells via activation of p53.
Cancer Invest.
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Sakai H, Moriura Y, Notomi T, Kawawaki J, Ohnishi K, Kuno M.
Phospholipase C-dependent Ca2+-sensing pathways leading to endocytosis and inhibition of the plasma membrane vacuolar H+-ATPase in osteoclasts.
Am. J. Physiol., Cell Physiol.
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Yasuzaki Y, Yamada Y, Harashima H.
Mitochondrial matrix delivery using MITO-Porter, a liposome-based carrier that specifies fusion with mitochondrial membranes.
Biochem. Biophys. Res. Commun.
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Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nonaka K, Yamashita Y.
Involvement of the JAK-STAT pathway and SOCS3 in the regulation of adiponectin-generated reactive oxygen species in murine macrophage RAW 264 cells.
J. Cell. Biochem.
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Kato Y, Koide N, Komatsu T, Tumurkhuu G, Dagvadorj J, Kato K, Yokochi T.
Metformin attenuates production of nitric oxide in response to lipopolysaccharide by inhibiting MyD88-independent pathway.
Horm. Metab. Res.
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Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation.
Cell. Immunol.
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Ohata S, Moriyama C, Yamashita A, Nishida T, Kusumoto C, Mochida S, Minami Y, Nakada J, Shomori K, Inagaki Y, Ohta Y, Matsura T.
Polaprezinc Protects Mice against Endotoxin Shock.
J Clin Biochem Nutr
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Yamaguchi N, Hamachi T, Kamio N, Akifusa S, Masuda K, Nakamura Y, Nonaka K, Maeda K, Hanazawa S, Yamashita Y.
Expression levels of adiponectin receptors and periodontitis.
J. Periodont. Res.
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Xiao G, Miyazato A, Abe Y, Zhang T, Nakamura K, Inden K, Tanaka M, Tanno D, Miyasaka T, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Yamamoto N, Kunishima H, Hirakata Y, Kaku M, Kawakami K.
Activation of myeloid dendritic cells by deoxynucleic acids from Cordyceps sinensis via a Toll-like receptor 9-dependent pathway.
Cell. Immunol.
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Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Retinoblastoma protein-interacting zinc finger 1 (RIZ1) participates in RANKL-induced osteoclast formation via regulation of NFATc1 expression.
Immunol. Lett.
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Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS.
Immunology
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Kitagawa Y, Tohya Y, Ike F, Kajita A, Park SJ, Ishii Y, Kyuwa S, Yoshikawa Y.
Indirect ELISA and indirect immunofluorescent antibody assay for detecting the antibody against murine norovirus S7 in mice.
Exp. Anim.
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Shimoda H, Shan SJ, Tanaka J, Seki A, Seo JW, Kasajima N, Tamura S, Ke Y, Murakami N.
Anti-inflammatory properties of red ginger (Zingiber officinale var. Rubra) extract and suppression of nitric oxide production by its constituents.
J Med Food
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Tsukamoto H, Fukudome K, Takao S, Tsuneyoshi N, Kimoto M.
Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.
Int. Immunol.
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Arisaka M, Nakamura T, Yamada A, Negishi Y, Aramaki Y.
Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells.
FEBS Lett.
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Hakozaki A, Yoda M, Tohmonda T, Furukawa M, Hikata T, Uchikawa S, Takaishi H, Matsumoto M, Chiba K, Horiuchi K, Toyama Y.
Receptor activator of NF-kappaB (RANK) ligand induces ectodomain shedding of RANK in murine RAW264.7 macrophages.
J. Immunol.
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Suzuki T, Chang MO, Kitajima M, Takaku H.
Baculovirus activates murine dendritic cells and induces non-specific NK cell and T cell immune responses.
Cell. Immunol.
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Hirai S, Uemura T, Mizoguchi N, Lee JY, Taketani K, Nakano Y, Hoshino S, Tsuge N, Narukami T, Yu R, Takahashi N, Kawada T.
Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages.
Mol Nutr Food Res
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Matsubara T, Ikeda F, Hata K, Nakanishi M, Okada M, Yasuda H, Nishimura R, Yoneda T.
Cbp recruitment of Csk into lipid rafts is critical to c-Src kinase activity and bone resorption in osteoclasts.
J. Bone Miner. Res.
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Deoxynivalenol and nivalenol inhibit lipopolysaccharide-induced nitric oxide production by mouse macrophage cells.
Toxicol. Lett.
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Kishimoto Y, Tani M, Uto-Kondo H, Iizuka M, Saita E, Sone H, Kurata H, Kondo K.
Astaxanthin suppresses scavenger receptor expression and matrix metalloproteinase activity in macrophages.
Eur J Nutr
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Chen J, Uto T, Tanigawa S, Yamada-Kato T, Fujii M, Hou DX.
Microarray-based determination of anti-inflammatory genes targeted by 6-(methylsulfinyl)hexyl isothiocyanate in macrophages.
Exp Ther Med
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Kaori Yoshino, Kaoru Saijo, Chikako Noro and Yukio Nakamura
Development of a simple method to determine the mouse strain from which cultured cell lines originated
Interdisciplinary Bio Central
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Miyazaki T, Miyauchi S, Tawada A, Anada T, Suzuki O.
Effect of chondroitin sulfate-E on the osteoclastic differentiation of RAW264 cells.
Dent Mater J
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Lee JW, Ahn JY, Hasegawa S, Cha BY, Yonezawa T, Nagai K, Seo HJ, Jeon WB, Woo JT.
Inhibitory effect of luteolin on osteoclast differentiation and function.
Cytotechnology
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beta-Carotene and beta-cryptoxanthin but not lutein evoke redox and immune changes in RAW264 murine macrophages.
Mol Nutr Food Res
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Shioiri T, Muroi M, Hatao F, Nishida M, Ogawa T, Mimura Y, Seto Y, Kaminishi M, Tanamoto K.
Caspase-3 is activated and rapidly released from human umbilical vein endothelial cells in response to lipopolysaccharide.
Biochim. Biophys. Acta
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Kamio N, Akifusa S, Yamaguchi N, Nonaka K, Yamashita Y.
Anti-inflammatory activity of a globular adiponectin function on RAW 264 cells stimulated by lipopolysaccharide from Aggregatibacter actinomycetemcomitans.
FEMS Immunol. Med. Microbiol.
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Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Thalidomide inhibits lipopolysaccharide-induced nitric oxide production and prevents lipopolysaccharide-mediated lethality in mice.
FEMS Immunol. Med. Microbiol.
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Miyazato A, Nakamura K, Yamamoto N, Mora-Montes HM, Tanaka M, Abe Y, Tanno D, Inden K, Gang X, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Mitsutake K, Gow NA, Kaku M, Kawakami K.
Toll-like receptor 9-dependent activation of myeloid dendritic cells by Deoxynucleic acids from Candida albicans.
Infect. Immun.
2009
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Seddek Al, Mahmoud ME, Shiina T, Hirayama H, Iwami M, Miyazawa S, Nikami H, Takewaki T, Shimizu Y.
Extract from Calotropis procera latex activates murine macrophages.
J Nat Med
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Tomimori Y, Mori K, Koide M, Nakamichi Y, Ninomiya T, Udagawa N, Yasuda H.
Evaluation of pharmaceuticals with a novel 50-hour animal model of bone loss.
J. Bone Miner. Res.
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Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2.
Free Radic. Biol. Med.
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Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y.
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Biochem. Biophys. Res. Commun.
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Hassan F, Islam S, Tumurkhuu G, Dagvadorj J, Naiki Y, Komatsu T, Koide N, Yoshida T, Yokochi T.
Involvement of interleukin-1 receptor-associated kinase (IRAK)-M in toll-like receptor (TLR) 7-mediated tolerance in RAW 264.7 macrophage-like cells.
Cell. Immunol.
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Concanavalin A induces formation of osteoclast-like cells in RAW 264.7 mouse macrophage cells.
Immunopharmacol Immunotoxicol
2009
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Iftakhar-E-Khuda I, Koide N, Hassan F, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Novel mechanism of U18666A-induced tumour necrosis factor-alpha production in RAW 264.7 macrophage cells.
Clin. Exp. Immunol.
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Noman AS, Koide N, Hassan F, I-E-Khuda I, Dagvadorj J, Tumurkhuu G, Islam S, Naiki Y, Yoshida T, Yokochi T.
Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression.
Innate Immun
2009
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Inden K, Kaneko J, Miyazato A, Yamamoto N, Mouri S, Shibuya Y, Nakamura K, Aoyagi T, Hatta M, Kunishima H, Hirakata Y, Itoh Y, Kaku M, Kawakami K.
Toll-like receptor 4-dependent activation of myeloid dendritic cells by leukocidin of Staphylococcus aureus.
Microbes Infect.
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Nakamura T, Kodama N, Arai Y, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ishikawa T, Ueno K, Yano S.
Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7.
J Nat Med
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Inhibitory effect of the extracts from Thai medicinal plants on iNOS expression in mouse macrophage RAW 264.7.
J Nat Med
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The structure-activity relationship between oxycoumarin derivatives showing inhibitory effects on iNOS in mouse macrophage RAW264.7 cells.
J Nat Med
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Receptor expression modulates the specificity of transforming growth factor-beta signaling pathways.
Genes Cells
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Tsuji M, Yamamoto H, Sato T, Mizuha Y, Kawai Y, Taketani Y, Kato S, Terao J, Inakuma T, Takeda E.
Dietary quercetin inhibits bone loss without effect on the uterus in ovariectomized mice.
J Bone Miner Metab
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DNA Microarray Analyses of the Effects of LPS-stimulation and IC50 Nickel Ions on Gene Expressions of Mouse Macrophage-like Cell Line RAW264
Nano Biomedicine
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Ken Shirato, Takako Kizaki, Takuya Sakurai, Jun-Etsu Ogasawara, Yoshinaga Ishibashi, Takehiko Iijima, Chikako Okada, Izumi Noguchi, Kazuhiko Imaizumi, Naoyuki Taniguchi, Hideki Ohno
Hypoxia-inducible factor-1alpha suppresses the expression of macrophage scavenger receptor 1
Pflugers Arch
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Regulation of globular adiponectin-induced apoptosis by reactive oxygen/nitrogen species in RAW264 macrophages.
Free Radic. Biol. Med.
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Yoshida H, Kwon AH, Habara K, Yamada M, Kaibori M, Kamiyama Y, Nishizawa M, Ito S, Okumura T.
Edaravone inhibits the induction of iNOS gene expression at transcriptional and posttranscriptional steps in murine macrophages.
Shock
2008
30:734-9
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Nishida K, Kuchiiwa S, Oiso S, Futagawa T, Masuda S, Takeda Y, Yamada K.
Up-regulation of matrix metalloproteinase-3 in the dorsal root ganglion of rats with paclitaxel-induced neuropathy.
Cancer Sci
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99(8):1618-25
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Ando M, Tu W, Nishijima K, Iijima S.
Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs.
Biochem Biophys Res Commun
2008
369(3):878-83
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6521
Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H.
Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9.
J Biol Chem
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283(36):24682-9
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Murakami M, Kondo S, Funaba M.
Expression and function of alternative splice variants of the mouse TGF-beta type I receptor
Cell Biol Int
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32(7):848-54
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Taira M, Sasaki K, Saitoh S, Nezu T, Sasaki M, Kimura S, Terasaki K, Sera K, Narushima T, Araki Y.
Accumulation of element Ti in macrophage-like RAW264 cells cultured in medium with 1 ppm Ti and effects on cell viability, SOD production and TNF-alpha secretion.
Dent Mater J
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25:726-32
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8850
Yamaguchi N, Kukita T, Li YJ, Martinez Argueta JG, Saito T, Hanazawa S, Yamashita Y.
Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.
FEMS Immunol. Med. Microbiol.
2007
49:28-34
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4889
Takayoshi Suganami, Kanami Tanimoto-Koyama, Junko Nishida, Michiko Itoh, Xunmei Yuan, Shinji Mizuarai, Hidehito Kotani, Shoji Yamaoka, Kensuke Miyake, Seiichiro Aoe, Yasutomi Kamei and Yoshihiro Ogawa
Role of the Toll-like Receptor 4/NF-κB Pathway in Saturated Fatty Acid−Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages
Arterioscler Thromb Vasc Biol
2007
27:84-91
PubMed ID: 17082484
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7269
Takarada T, Hinoi E, Kambe Y, Sahara K, Kurokawa S, Takahata Y, Yoneda Y.
Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative cytotoxicity of ascorbic acid.
Eur J Pharmacol
2007
575(1-3):1-11
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7349
Ito M, Haito S, Furumoto M, Uehata Y, Sakurai A, Segawa H, Tatsumi S, Kuwahata M, Miyamoto K.
Unique uptake and efflux systems of inorganic phosphate in osteoclast-like cells.
Am J Physiol Cell Physiol
2007
292(1):C526-34
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7387
Murakami Y, Hirata A, Ito S, Shoji M, Tanaka S, Yasui T, Machino M, Fujisawa S.
Re-evaluation of cyclooxygenase-2-inhibiting activity of vanillin and guaiacol in macrophages stimulated with lipopolysaccharide.
Anticancer Res
2007
27(2):801-7
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12320
Masayori Hagimori, Eri Hatabe, Kohei Sano, Hirotaka Miyazaki, Hitoshi Sasaki, Hideo Saji, Takahiro Mukai
An Activatable Fluorescent γ-Polyglutamic Acid Complex for Sentinel Lymph Node Imaging
Biol Pharm Bull
2007
40(3):297-302
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12814
Uto T, Fujii M, Hou DX.
Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-gamma and 12-O-tetradecanoylphorbol-13-acetate
Oncol Rep
2007
17(1):233-8
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8917
Soji Fukumoto, Paramasari Dirgahayu, Kozue Nunomura, Haruyo Matsuura andKazumitsu Hirai
Suppression of LPS-induced Cyclooxygenase-2 (cox-2) Gene Expression in Mouse Macrophages by Excretory/Secretory Products of Spirometra erinaceieuropaei Plerocercoids
Yonago Acta Med.
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49:39-47
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6489
Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A.
TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.
Arthritis Res Ther
2006
8(5):R146
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7020
Murakami Y, Shoji M, Ogiwara T, Tanaka S, Yokoe I, Fujisawa S.
Preventive effect of ortho dimer of butylated hydroxyanisole on activator protein-1 activation and cyclooxygenase-2 expression in macrophages stimulated by fimbriae of Porphyromonas gingivalis, an oral anaerobe.
Anticancer Res
2006
26(4B):2915-20
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7039
Funaba M, Nakaya K, Ikeda T, Murakami M, Tsuchida K, Sugino H.
Requirement of Smad3 for mast cell growth.
Cell Immunol
2006
240(1):47-52
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13660
Kimura Y, Sumiyoshi M, Suzuki T, Sakanaka M.
Antitumor and antimetastatic activity of a novel water-soluble low molecular weight beta-1, 3-D-glucan (branch beta-1,6) isolated from Aureobasidium pullulans 1A1 strain black yeast
Anticancer Res
2006
26(6B):4131-41
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13729
Imamura T, Bando N, Yamanishi R.
Beta-carotene modulates the immunological function of RAW264, a murine macrophage cell line, by enhancing the level of intracellular glutathione
Biosci Biotechnol Biochem
2006
70(9):2112-20.
PubMed ID: 16960387
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3160
Wei, Ping, Taniguchi, Susumu, Sakai, Yoshiyuki, Imamura, Minako, Inoguchi, Toyoshi, Nawata, Hajime, Oda, Shinya, Nakabeppu, Yusaku, Nishimura, Junji, Ikuyama, Shoichiro
Expression of adipose differentiation-related protein (ADRP) is conjointly regulated by PU.1 and AP-1 in macrophages.
J Biochem
2005
138:399-412
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2903
Shimomura-Shimizu M, Sugiyama K, Muroi M, Tanamoto K
Alachlor and carbaryl suppress lipopolysaccharide-induced iNOS expression by differentially inhibiting NF-kappaB activation.
Biochem Biophys Res Commun
2005
332:793-9
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2922
Musikacharoen, Tipayaratn, Oguma, Asako, Yoshikai, Yasunobu, Chiba, Norika, Masuda, Akio, Matsuguchi, Tetsuya
Interleukin-15 induces IL-12 receptor beta1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling.
Blood
2005
105:711-20
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3365
Ito, Mikiko, Matsuka, Naoko, Izuka, Michiyo, Haito, Sakiko, Sakai, Yuko, Nakamura, Rie, Segawa, Hiroko, Kuwahata, Masashi, Yamamoto, Hironori, Pike, Wesley J, Miyamoto, Ken-ichi
Characterization of inorganic phosphate transport in osteoclast-like cells.
Am J Physiol Cell Physiol
2005
288:C921-31
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3392
Aki, Daisuke, Mashima, Ryuichi, Saeki, Kazuko, Minoda, Yasumasa, Yamauchi, Moriyasu, Yoshimura, Akihiko
Modulation of TLR signalling by the C-terminal Src kinase (Csk) in macrophages.
Genes Cells
2005
10:357-68
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3232
Arakawa, Reijiro, Tamehiro, Norimasa, Nishimaki-Mogami, Tomoko, Ueda, Kazumitsu, Yokoyama, Shinji
Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter A1 gene in a liver X receptor-dependent manner.
Arterioscler Thromb Vasc Biol
2005
25:1193-7
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3210
Hou, De-Xing, Yanagita, Takashi, Uto, Takuhiro, Masuzaki, Satoko, Fujii, Makoto
Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved.
Biochem Pharmacol
2005
70:417-25
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3190
Hassan, Ferdaus, Islam, Shamima, Mu, Mya Mya, Ito, Hiroyasu, Koide, Naoki, Mori, Isamu, Yoshida, Tomoaki, Yokochi, Takashi
Lipopolysaccharide prevents doxorubicin-induced apoptosis in RAW 264.7 macrophage cells by inhibiting p53 activation.
Mol Cancer Res
2005
3:373-9
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3098
Suganami, Takayoshi, Nishida, Junko, Ogawa, Yoshihiro
A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha.
Arterioscler Thromb Vasc Biol
2005
25:2062-2068
PubMed ID: 16123319
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3209
Uto, Takuhiro, Fujii, Makoto, Hou, De-Xing
6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages.
Biochem Pharmacol
2005
70:1211-21
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8972
Kim TS, Nakagawa T, Kita T, Higashi T, Takebayashi S, Matsumoto M, Kojima K, Sakamoto T, Ito J.
Neural connections between embryonic stem cell-derived neurons and vestibular hair cells in vitro.
Brain Res.
2005
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Kobayashi Y, Mizoguchi T, Take I, Kurihara S, Udagawa N, Takahashi N.
Prostaglandin E2 enhances osteoclastic differentiation of precursor cells through protein kinase A-dependent phosphorylation of TAK1.
J. Biol. Chem.
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280:11395-403
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Abe T, Hemmi H, Miyamoto H, Moriishi K, Tamura S, Takaku H, Akira S, Matsuura Y.
Involvement of the Toll-like receptor 9 signaling pathway in the induction of innate immunity by baculovirus.
J Virol
2005
79(5):2847-58
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5921
Uto T, Fujii M, Hou DX.
Inhibition of lipopolysaccharide-induced cyclooxygenase-2 transcription by 6-(methylsulfinyl) hexyl isothiocyanate, a chemopreventive compound from Wasabia japonica (Miq.) Matsumura, in mouse macrophages.
Biochem Pharmacol
2005
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Hirata A, Murakami Y, Atsumi T, Shoji M, Ogiwara T, Shibuya K, Ito S, Yokoe I, Fujisawa S.
Ferulic acid dimer inhibits lipopolysaccharide-stimulated cyclooxygenase-2 expression in macrophages.
In Vivo
2005
19(5):849-53
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6869
Hirata A, Murakami Y, Shoji M, Kadoma Y, Fujisawa S.
Kinetics of radical-scavenging activity of hesperetin and hesperidin and their inhibitory activity on COX-2 expression.
Anticancer Res
2005
25(5):3367-74
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6873
Murakami Y, Ito S, Atsumi T, Fujisawa S.
Theoretical prediction of the relationship between phenol function and COX-2/AP-1 inhibition for ferulic acid-related compounds.
In Vivo
2005
19(6):1039-43
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6874
Okada N, Hirata A, Murakami Y, Shoji M, Sakagami H, Fujisawa S.
Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression by eugenol-related compounds.
Anticancer Res
2005
25(5):3263-9
PubMed ID: 16101137
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Tomohiro Konno, Hirokazu Hasuda, Kazuhiko Ishihara, Yoshihiro Ito
Photo-immobilization of a phospholipid polymer for surface modification
Biomaterials
2005
26(12):1381-8
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12263
Hirokazu Hasuda , Oh Hyeong Kwon, Inn-Kyu Kang, Yoshihiro Ito
Synthesis of photoreactive pullulan for surface modification
Biomaterials
2005
26(15):2401-6
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2890
Ito T, Morimatsu M, Oonuma T, Shiina T, Kitamura H, Syuto B
Transcriptional regulation of the MAIL gene in LPS-stimulated RAW264 mouse macrophages.
Gene
2004
342:137-43
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2904
Itoh CE, Kizaki T, Hitomi Y, Hanawa T, Kamiya S, Ookawara T, Suzuki K, Izawa T, Saitoh D, Haga S, Ohno H
Down-regulation of beta2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation.
Biochem Biophys Res Commun
2004
322:979-84
PubMed ID: 15336560
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3200
Suzuki, Shogo, Nishimaki-Mogami, Tomoko, Tamehiro, Norimasa, Inoue, Kazuhide, Arakawa, Reijiro, Abe-Dohmae, Sumiko, Tanaka, Arowu R, Ueda, Kazumitsu, Yokoyama, Shinji
Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism.
Arterioscler Thromb Vasc Biol
2004
24:519-25
PubMed ID: 14726413
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3229
Okuhira, Kei-ichiro, Tsujita, Maki, Yamauchi, Yoshio, Abe-Dohmae, Sumiko, Kato, Koichi, Handa, Tetsurou, Yokoyama, Shinji
Potential involvement of dissociated apoA-I in the ABCA1-dependent cellular lipid release by HDL.
J Lipid Res
2004
45:645-52
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3193
Ban, Hyun Seung, Suzuki, Katsuya, Lim, Soon Sung, Jung, Sang Hoon, Lee, Sanghyun, Ji, Jun, Lee, Hye Seung, Lee, Yeon Sil, Shin, Kuk Hyun, Ohuchi, Kazuo
Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by 2'-hydroxychalcone derivatives in RAW 264.7 cells.
Biochem Pharmacol
2004
67:1549-57
PubMed ID: 15041472
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3212
Kato, Sawako, Yuzawa, Yukio, Tsuboi, Naotake, Maruyama, Shoichi, Morita, Yoshiki, Matsuguchi, Tetsuya, Matsuo, Seiichi
Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4.
J Am Soc Nephrol
2004
15:1289-99
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2688
Takahashi, Tetsuyuki, Takasuka, Nobuo, Iigo, Masaaki, Baba, Masaki, Nishino, Hoyoku, Tsuda, Hiroyuki, Okuyama, Toru
Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development.
Cancer Sci
2004
95:448-53
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3220
Adachi, Yoshiyuki, Ishii, Takashi, Ikeda, Yoshihiko, Hoshino, Akiyoshi, Tamura, Hiroshi, Aketagawa, Jun, Tanaka, Shigenori, Ohno, Naohito
Characterization of beta-glucan recognition site on C-type lectin, dectin 1.
Infect Immun
2004
72:4159-71
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3364
Hatao, Fumihiko, Muroi, Masashi, Hiki, Naoki, Ogawa, Toshihisa, Mimura, Yoshikazu, Kaminishi, Michio, Tanamoto, Ken-ichi
Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein.
J Leukoc Biol
2004
76:904-8
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3197
Matsumoto, Masahito, Kogawa, Masakazu, Wada, Seiki, Takayanagi, Hiroshi, Tsujimoto, Masafumi, Katayama, Shigehiro, Hisatake, Koji, Nogi, Yasuhisa
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1.
J Biol Chem
2004
279:45969-79
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2865
Ikeda, Fumiyo, Nishimura, Riko, Matsubara, Takuma, Tanaka, Sakae, Inoue, Jun-ichiro, Reddy, Sakamuri V, Hata, Kenji, Yamashita, Kenji, Hiraga, Toru, Watanabe, Toshiyuki, Kukita, Toshio, Yoshioka, Katsuji, Rao, Anjana, Yoneda, Toshiyuki
Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation.
J Clin Invest
2004
114:475-84
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Kimura T. et al.
Novel PVA-DNA nanoparticles prepared by ultra high pressure technology for gene delivery.
Materials Science and Engineering C
2004
24:797-801
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6477
Ogasawara T, Katagiri M, Yamamoto A, Hoshi K, Takato T, Nakamura K, Tanaka S, Okayama H, Kawaguchi H.
Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).
J Bone Miner Res
2004
19(7):1128-36
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6737
Naruse M, Otsuka E, Naruse M, Ishihara Y, Miyagawa-Tomita S, Hagiwara H.
Inhibition of osteoclast formation by 3-methylcholanthrene, a ligand for arylhydrocarbon receptor: suppression of osteoclast differentiation factor in osteogenic cells.
Biochem Pharmacol
2004
67(1):119-27
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13881
Sato A, Keng VW, Yamamoto T, Kasamatsu S, Ban T, Tanaka H, Satoh S, Yamada K, Noguchi T.
Identification and characterization of the hematopoietic cell-specific enhancer-like element of the mouse hex gene
J Biochem
2004
135(2):259-68
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6705
Murakami Y, Shoji M, Hanazawa S, Tanaka S, Fujisawa S.
Preventive effect of bis-eugenol, a eugenol ortho dimer, on lipopolysaccharide-stimulated nuclear factor kappa B activation and inflammatory cytokine expression in macrophages.
Biochem Pharmacol
2003
66(6):1061-6
PubMed ID: 12963494
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2664
Kizaki, Takako, Suzuki, Kenji, Hitomi, Yoshiaki, Taniguchi, Naoyuki, Saitoh, Daizoh, Watanabe, Kenji, Onoe, Kazunori, Day, Noorbibi K, Good, Robert A, Ohno, Hideki
Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages.
Proc Natl Acad Sci U S A
2002
99:9392-7
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2654
Muroi, Masashi, Tanamoto, Ken-Ichi
The polysaccharide portion plays an indispensable role in Salmonella lipopolysaccharide-induced activation of NF-kappaB through human toll-like receptor 4.
Infect Immun
2002
70:6043-7
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Kinjyo I, Hanada T, Inagaki-Ohara K, Mori H, Aki D, Ohishi M, Yoshida H, Kubo M, Yoshimura A.
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation.
Immunity
2002
17(5):583-91
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Yamamoto A, Miyazaki T, Kadono Y, Takayanagi H, Miura T, Nishina H, Katada T, Wakabayashi K, Oda H, Nakamura K, Tanaka S.
Possible involvement of IkappaB kinase 2 and MKK7 in osteoclastogenesis induced by receptor activator of nuclear factor kappaB ligand.
J Bone Miner Res
2002
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Naraba H, Yokoyama C, Tago N, Murakami M, Kudo I, Fueki M, Oh-Ishi S, Tanabe T.
Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1.
J Biol Chem
2002
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Haruta I, Kato Y, Hashimoto E, Minjares C, Kennedy S, Uto H, Yamauchi K, Kobayashi M, Yusa S, Muller U, Hayashi N, Miyazaki T
Association of AIM, a novel apoptosis inhibitory factor, with hepatitis via supporting macrophage survival and enhancing phagocytotic function of macrophages.
J Biol Chem
2001
276:22910-4
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Genomic organization, chromosomal localization, and promoter analysis of the mouse Mail gene.
Immunogenetics
2001
53:649-55
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Enhancement of gene expression by polyamidoamine dendrimer conjugates with alpha-, beta-, and gamma-cyclodextrins.
Bioconjug Chem
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Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors.
J Immunol
2001
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Oxidative and Nitrosative Stress in Acute Renal Ischemia
Am J Physiol Renal Physiol
2001
281 (5), F948-57
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Characterization of apolipoprotein-mediated HDL generation induced by cAMP in a murine macrophage cell line.
Biochemistry
2000
39:11092-9
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Enhancement of the cAMP-induced apolipoprotein-mediated cellular lipid release by calmodulin inhibitors W7 and W5 from RAW 264 mouse macrophage cell line cells.
J Cardiovasc Pharmacol
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Activation of p38 mitogen-activated protein kinase is crucial in osteoclastogenesis induced by tumor necrosis factor.
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Prostaglandin E2 stimulates AP-1-mediated CD14 expression in mouse macrophages via cyclic AMP-dependent protein kinase A.
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Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL).
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A physiologic role of Bcl-xL induced in activated macrophages.
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Modification of Immunopharmacologicaln Activities of Synthetic Monosaccharide Lipid A Analogue, GLA60, by Lysozyme
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Involvement of Salmonella enterica serovar Typhi RpoS in resistance to NO-mediated host defense against serovar Typhi infection
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