CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [RCB0535 : RAW 264]

716 Ralph P, Nakoinz I Antibody-dependent killing of erythrocyte and tumor targets by macrophage-related cell lines: enhancement by PPD and LPS. J Immunol 1977 119:950-54 PubMed ID: 894031

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20345 Thein HSS, Hashimoto K, Kawashima N, Noda S, Okiji T. Evaluation of the anti-inflammatory effects of surface-reaction-type pre-reacted glass-ionomer filler containing root canal sealer in lipopolysaccharide-stimulated RAW264.7 macrophages. Dent Mater J 2022 PubMed ID: 34602587

20526 Aki T, Funakoshi T, Unuma K, Uemura K. Inverse regulation of GSDMD and GSDME gene expression during LPS-induced pyroptosis in RAW264.7 macrophage cells. Apoptosis 2022 PubMed ID: 35006493

20542 Do KM, Kodama T, Shin MK, Nu LHT, Nguyen HM, Dang SV, Shiokawa KI, Hayakawa Y, Morita H. Marginols A‒H, unprecedented pimarane diterpenoids from Kaempferia marginata and their NO inhibitory activities. Phytochemistry 2022 196:113109 PubMed ID: 35091214

16213 Jing‐Yi Xue, Giedre Grigelioniene, Zheng Wang, Gen Nishimura, Aritoshi Iida, Naomichi Matsumoto, Emma Tham, Noriko Miyake, Shiro Ikegawa, Long Guo SLC4A2 Deficiency Causes a New Type of Osteopetrosis J Bone Miner Res 2022 37(2):226-235 PubMed ID: 34668226

20578 Akashi Y, Nagasaki A, Okawa H, Matsumoto T, Kondo T, Yatani H, Nishimura I, Egusa H. Cyclic Pressure-Induced Cytokines from Gingival Fibroblasts Stimulate Osteoclast Activity: Clinical Implications for Alveolar Bone Loss in Denture Wearers. J Prosthodont Res 2022 PubMed ID: 35185110

16345 Kumawat M, Madhyastha H, Umapathi A, Singh M, Revaprasadu N, Daima HK. Surface Engineered Peroxidase-Mimicking Gold Nanoparticles to Subside Cell Inflammation Langmuir 2022 38(5):1877-1887 PubMed ID: 35099982

20620 Kieu TQ, Tazawa K, Kawashima N, Noda S, Fujii M, Nara K, Hashimoto K, Han P, Okiji T. Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitro. Sci Rep 2022 12(1):5176 PubMed ID: 35338195

20635 Shinomiya K, Mukai A, Ito E, Yoneda K, Ueno M, Sotozono C, Kinoshita S, Hamuro J. Potential participation of CTRP6, a complement regulator, in the pathology of age related macular degeneration. Jpn J Ophthalmol 2022 PubMed ID: 35397057

20655 Temizoz B, Hioki K, Kobari S, Jounai N, Kusakabe T, Lee MSJ, Coban C, Kuroda E, Ishii KJ. Anti-tumor immunity by transcriptional synergy between TLR9 and STING activation. Int Immunol 2022 PubMed ID: 35419609

20689 Li W, Miyashita A, Sekimizu K. Peanut triacylglycerols activate innate immunity both in insects and mammals. Sci Rep 2022 12(1):7464 PubMed ID: 35523841

16504 Zhou Y, Takano T, Li X, Wang Y, Wang R, Zhu Z, Tanokura M, Miyakawa T, Hachimura S. β-elemene regulates M1-M2 macrophage balance through the ERK/JNK/P38 MAPK signaling pathway Commun Biol 2022 5(1):519 PubMed ID: 35641589

16619 Mohamed IMA, Jamsransuren D, Matsuda S, Ogawa H, Takeda Y. Impact of Theaflavins-Enriched Tea Leaf Extract TY-1 against Surrogate Viruses of Human Norovirus: In Vitro Virucidal Study Pathogens 2022 11(5):533 PubMed ID: 35631054

16642 Gulay KCM, Aoshima K, Maekawa N, Suzuki T, Konnai S, Kobayashi A, Kimura T. Hemangiosarcoma cells induce M2 polarization and PD-L1 expression in macrophages Sci Rep 2022 12(1):2124 PubMed ID: 35136176

16558 Ito S, Nishiguchi A, Ichimaru H, Nagasaka K, Hirade H, Taguchi T. Prevention of postoperative adhesion with a colloidal gel based on decyl group-modified Alaska pollock gelatin microparticles Acta Biomater 2022 S1742-7061(22)00354-3 PubMed ID: 35697199

16540 Elia Marin, Tetsuya Adachi, Francesco Boschetto, Wenliang Zhu, Keiji Adachi, Narisato Kanamura, Toshiro Yamamoto, Giuseppe Pezzotti Raman Spectroscopic Investigation of Osteoclastic Activity under the Influence of Bisphosphonate Applied Sciences 2022 12:3757

16385 Shan Q, Takabatake K, Kawai H, Oo MW, Inada Y, Sukegawa S, Fushimi S, Nakano K, Nagatsuka H. Significance of cancer stroma for bone destruction in oral squamous cell carcinoma using different cancer stroma subtypes Oncol Rep 2022 47(4):81 PubMed ID: 35211756

20820 Kurata A, Kiyohara S, Imai T, Yamasaki-Yashiki S, Zaima N, Moriyama T, Kishimoto N, Uegaki K. Characterization of extracellular vesicles from Lactiplantibacillus plantarum. Sci Rep 2022 12(1):13330 PubMed ID: 35941134

20823 Shi Y, Yasui M, Hara-Chikuma M. AQP9 transports lactate in tumor-associated macrophages to stimulate an M2-like polarization that promotes colon cancer progression. Biochem Biophys Rep 2022 31:101317 PubMed ID: 35967760

17097 Kartikasari N, Yamada M, Watanabe J, Tiskratok W, He X, Kamano Y, Egusa H. Titanium surface with nanospikes tunes macrophage polarization to produce inhibitory factors for osteoclastogenesis through nanotopographic cues Acta Biomater 2022 137:316-330 PubMed ID: 34673230

20837 Ueno S, Sudo T, Saya H, Sugihara E. Pigment epithelium-derived factor promotes peritoneal dissemination of ovarian cancer through induction of immunosuppressive macrophages. Commun Biol 2022 5(1):904 PubMed ID: 36056141

20863 Tanaka KI, Nakaguchi S, Shiota S, Nakada Y, Oyama K, Sakakibara O, Shimoda M, Sugimoto A, Ichitani M, Takihara T, Kinugasa H, Kawahara M. Preventive Effect of Epigallocatechin Gallate, the Main Component of Green Tea, on Acute Lung Injury Caused by Air Pollutants. Biomolecules 2022 12(9) PubMed ID: 36139034

13272 Tanaka KI, Kubota M, Shimoda M, Hayase T, Miyaguchi M, Kobayashi N, Ikeda M, Ishima Y, Kawahara M. Thioredoxin-albumin fusion protein prevents urban aerosol-induced lung injury via suppressing oxidative stress-related neutrophil extracellular trap formation. Environ Pollut 2021 PubMed ID: 33065363

13373 Kuriyama T, Fukuma Y, Imashiro C, Kabayama K, Kurashina Y, Takemura K. Detachment of RAW264.7 macrophages from a culture dish using ultrasound excited by a Langevin transducer. J Biosci Bioeng 2021 131(3):320-325 PubMed ID: 33250410

13464 Sugiyama T, Hobro AJ, Pavillon N, Umakoshi T, Verma P, Smith N. Label-free Raman mapping of saturated and unsaturated fatty acid uptake, storage, and return toward baseline levels in macrophages Analyst 2021 146(4):1268-1280 PubMed ID: 33346264

20004 Wada Y, Iyoda M, Matsumoto K, Suzuki T, Tachibana S, Kanazawa N, Honda H. Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice. PLoS One 2021 16(1):e0245340 PubMed ID: 33428678

20009 Li SW, Takahara T, Que W, Fujino M, Guo WZ, Hirano SI, Ye LP, Li XK. Hydrogen-rich water protects liver injury in nonalcoholic steatohepatitis though HO-1 enhancement via IL-10 and Sirt 1 signaling. Am J Physiol Gastrointest Liver Physiol 2021 PubMed ID: 33439102

20023 Madhyastha R, Madhyastha H, Nurrahmah QI, Purbasari B, Maruyama M, Nakajima Y. MicroRNA 21 Elicits a Pro-inflammatory Response in Macrophages, with Exosomes Functioning as Delivery Vehicles. Inflammation 2021 PubMed ID: 33501624

20065 Ma'mag LK, Zintchem AAA, Théodora KK, de Théodore AA, Lauve TY, Frédérich M, Bikobo DSN, Pegnyemb DE. Antiplasmodial and antileishmanial inhibitory activity of triterpenes and steroidal alkaloid from the leaves of Funtumia elastica (Preuss) Stapf (Apocynaceae). Fitoterapia 2021 104869 PubMed ID: 33657429

20088 Nurrahmah QI, Madhyastha R, Madhyastha H, Purbasari B, Maruyama M, Nakajima Y. Retinoic acid abrogates LPS-induced inflammatory response via negative regulation of NF-kappa B/miR-21 signaling. Immunopharmacol Immunotoxicol 2021 1-10 PubMed ID: 33757404

20176 Pengjam Y, Prajantasen T, Tonwong N, Panichayupakaranant P. Downregulation of miR-21 gene expression by CRE-Ter to modulate osteoclastogenesis: De Novo mechanism. Biochem Biophys Rep 2021 26:101002 PubMed ID: 33997317

20196 Sano K, Miki M, Tanaka T, Munemura M, Munekane M, Yamasaki T, Mukai T. Electrostatically self-assembled gold nanorods with chondroitin sulfate for targeted photothermal therapy for melanoma. Photodiagnosis Photodyn Ther 2021 102402 PubMed ID: 34144259

20197 Ju N, Hayashi H, Shimamura M, Yoshida S, Nakamaru R, Nakagami H, Morishita R, Rakugi H. Prevention of Acute Lung Injury by a Novel CD14-Inhibitory Receptor Activator of the NF-κB Ligand Peptide in Mice. Immunohorizons 2021 5(6):438-447 PubMed ID: 34131020

20199 Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S. Extracellular mRNA transported to the nucleus exerts translation-independent function. Nat Commun 2021 12(1):3655 PubMed ID: 34135341

20243 Hattori H, Takaoka K, Ueta M, Oshitani M, Tamaoka J, Noguchi K, Kishimoto H. Senescent RAW264.7 cells exhibit increased production of nitric oxide and release inducible nitric oxide synthase in exosomes. Mol Med Rep 2021 24(3) PubMed ID: 34318909

20258 Yokota S, Matsumae G, Shimizu T, Hasegawa T, Ebata T, Takahashi D, Heguo C, Tian Y, Alhasan H, Takahata M, Kadoya K, Terkawi MA, Iwasaki N. Cardiotrophin like cytokine factor 1 (CLCF1) alleviates bone loss in osteoporosis mouse models by suppressing osteoclast differentiation through activating interferon signaling and repressing the nuclear factor-κB signaling pathway. Bone 2021 116140 PubMed ID: 34364014

20264 Kawai K, Nishigaki A, Moriya S, Egami Y, Araki N. Rab10-Positive Tubular Structures Represent a Novel Endocytic Pathway That Diverges From Canonical Macropinocytosis in RAW264 Macrophages. Front Immunol 2021 12:649600 PubMed ID: 34135890

20271 Takahashi F, Endo K, Matsui R, Yamamoto K, Tanaka S. Brassica rapa L. activates macrophages via Toll-like receptors. Biosci Biotechnol Biochem 2021 85(3):656-665 PubMed ID: 33589925

15168 Hangai S, Kawamura T, Kimura Y, Chang CY, Hibino S, Yamamoto D, Nakai Y, Tateishi R, Oshima M, Oshima H, Kodama T, Moriya K, Koike K, Yanai H, Taniguchi T. Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells Nat Immunol 2021 22(8):947-957 PubMed ID: 34239121

20285 Pavillon N, Smith NI. Deriving accurate molecular indicators of protein synthesis through Raman-based sparse classification. Analyst 2021 146(11):3633-3641 PubMed ID: 33949431

20313 Yamaguchi M, Takagi K, Sato M, Sato A, Miki Y, Onodera Y, Miyashita M, Sasano H, Suzuki T. Androgens enhance the ability of intratumoral macrophages to promote breast cancer progression. Oncol Rep 2021 46(3) PubMed ID: 34278480

20315 Cheng TY, Lin YJ, Saburi W, Vieths S, Scheurer S, Schülke S, Toda M. β-(1→4)-Mannobiose Acts as an Immunostimulatory Molecule in Murine Dendritic Cells by Binding the TLR4/MD-2 Complex. Cells 2021 10(7) PubMed ID: 34359943

15262 Tanikawa T, Kitamura M, Hayashi Y, Tomida N, Uwaya A, Isami F, Inoue Y. Anti-Inflammatory Effects of Morinda citrifolia Extract against Lipopolysaccharide-Induced Inflammation in RAW264 Cells Medicines (Basel) 2021 8(8):43 PubMed ID: 34436222

15263 Hiromu Ito Peroxynitrite Production Induced by LPS and X-ray Treatment Enhances Cellular Incorporation of Porphyrin in Mouse RAW264 Macrophages Applied Sciences 2021 11:3503

15264 Yamasaki M, Yamasaki Y, Furusho R, Kimura H, Kamei I, Sonoda H, Ikeda M, Oshima T, Ogawa K, Nishiyama K. Onion ( Allium cepa L.)-Derived Nanoparticles Inhibited LPS-Induced Nitrate Production, However, Their Intracellular Incorporation by Endocytosis Was Not Involved in This Effect on RAW264 Cells Molecules 2021 26(9):2763 PubMed ID: 34067155

15265 Nipitpon Srimai, Wasawat Kiatarkom, Hidetake Miyata Evaluation of the Effects of Hypo-Magnetic Fields on Mouse Macrophage RAW264 Cells International Journal of Chemistry 2021 13:12-20

15266 Kitazawa R, Haraguchi R, Kohara Y, Kitazawa S. RANK- NFATc1 signaling forms positive feedback loop on rank gene expression via functional NFATc1 responsive element in rank gene promoter Biochem Biophys Res Commun 2021 572:86-91 PubMed ID: 34358968

15267 Noguchi T, Hidaka K, Kobayashi S, Matsumoto K, Yoshioka M, Hu X, Maloney DJ, Yang SM, Kato S. A quinazoline-based bromodomain inhibitor, CN210, ameliorates indomethacin-induced ileitis in mice by inhibiting inflammatory cytokine expression Drug Dev Res 2021 21 Jun 1 PubMed ID: 34075610

15268 Tsuchiya K, Hosojima S, Hara H, Kushiyama H, Mahib MR, Kinoshita T, Suda T. Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes Cell Rep 2021 34(12):108887 PubMed ID: 33761363

15269 Takahashi K, Mizukami H, Osonoi S, Ogasawara S, Hara Y, Kudoh K, Takeuchi Y, Sasaki T, Daimon M, Yagihashi S. Inhibitory effects of xanthine oxidase inhibitor, topiroxostat, on development of neuropathy in db/db mice Neurobiol Dis 2021 155:105392 PubMed ID: 34000416

15270 Shinjyo N, Nakayama H, Li L, Ishimaru K, Hikosaka K, Suzuki N, Yoshida H, Norose K. Hypericum perforatum extract and hyperforin inhibit the growth of neurotropic parasite Toxoplasma gondii and infection-induced inflammatory responses of glial cells in vitro J Ethnopharmacol 2021 267:113525 PubMed ID: 33129946

15271 Kimura H, Tokuyama-Nakai S, Hirabayashi Y, Ishihara T, Jisaka M, Yokota K. Anti-inflammatory and bioavailability studies on dietary 3,5,4'-trihydroxy-6,7-methylenedioxyflavone-O-glycosides and their aglycone from indigo leaves in a murine model of inflammatory bowel disease J Pharm Biomed Anal 2021 193:113716 PubMed ID: 33152603

15272 Xi Yang, Satoru Komatsu, Sheethal Reghu, Eijiro Miyako Optically activatable photosynthetic bacteria-based highly tumor specific immunotheranostics Nano Today 2021 37:101100

15276 Yoshida H, Tsuhako R, Sugita C, Kurokawa M. Glucosyl Hesperidin Has an Anti-diabetic Effect in High-Fat Diet-Induced Obese Mice Biol Pharm Bull 2021 44(3):422-430 PubMed ID: 33642550

15280 Yukino Tsunekage, Masatoshi Takeiri, Yuri Yoshioka, Shinichi Matsumura, Yoshihide Kimura, Kohsuke Kataoka Nasturtium officinale Extract Suppresses Osteoclastogenesis in RAW 264 Cells by Inhibiting IκB-Kinase β Natural Product Communications 2021 16:1934578X2110206

15285 Fuchi Y, Murase H, Kai R, Kurata K, Karasawa S, Sasaki S. Artificial Host Molecules to Covalently Capture 8-Nitro-cGMP in Neutral Aqueous Solutions and in Cells Bioconjug Chem 2021 32(2):385-393 PubMed ID: 33529519

20352 Takenaga K, Koshikawa N, Nagase H. Intercellular transfer of mitochondrial DNA carrying metastasis-enhancing pathogenic mutations from high- to low-metastatic tumor cells and stromal cells via extracellular vesicles. BMC Mol Cell Biol 2021 22(1):52 PubMed ID: 34615464

15684 Kwaffo YA, Sarpong-Duah M, Owusu-Boateng K, Gbewonyo WS, Adjimani JP, Mosi L. Natural antioxidants attenuate mycolactone toxicity to RAW 264.7 macrophages Exp Biol Med (Maywood) 2021 246(17):1884-1894 PubMed ID: 34038223

20457 Hiyoshi M, Takahashi N, Eltalkhawy YM, Noyori O, Lotfi S, Panaampon J, Okada S, Tanaka Y, Ueno T, Fujisawa JI, Sato Y, Suzuki T, Hasegawa H, Tokunaga M, Satou Y, Yasunaga JI, Matsuoka M, Utsunomiya A, Suzu S. M-Sec induced by HTLV-1 mediates an efficient viral transmission. PLoS Pathog 2021 17(11):e1010126 PubMed ID: 34843591

15891 Rimpei Kamegawa, Mitsuru Naito, Satoshi Uchida, Hyun Jin Kim, Beob Soo Kim, Kanjiro Miyata Bioinspired Silicification of mRNA-Loaded Polyion Complexes for Macrophage-Targeted mRNA Delivery ACS Applied Bio Materials 2021 4:7790-7799

20495 Safitri FA, Tu ATT, Hoshi K, Shobo M, Zhao D, Witarto AB, Sumarsono SH, Giri-Rachman EA, Tsukakoshi K, Ikebukuro K, Yamazaki T. Enhancement of the Immunostimulatory Effect of Phosphodiester CpG Oligodeoxynucleotides by an Antiparallel Guanine-Quadruplex Structural Scaffold. Biomolecules 2021 11(11) PubMed ID: 34827615

16221 Yiting Li, Litong Ban, Shili Meng, Liang Huang, Ning Sun, Hongpeng Yang, Yu Wang, Linbo Wang Bioactivities of crude polysaccharide extracted from fermented soybean curd residue by Cordyceps militaris Biotechnology & Biotechnological Equipment 2021 35:342-353

16374 Xiao L, Shiwaku Y, Hamai R, Tsuchiya K, Sasaki K, Suzuki O. Macrophage Polarization Related to Crystal Phases of Calcium Phosphate Biomaterials Int J Mol Sci 2021 22(20):11252 PubMed ID: 34681912

16431 Do KM, Shin MK, Kodama T, Win NN, Prema P, Nguyen HM, Hayakawa Y, Morita H. Flavanols and Flavanes from Crinum asiaticum and Their Effects on LPS Signaling Pathway Through the Inhibition of NF-κB Activation Planta Med 2021 Sep 2 PubMed ID: 34474490

16531 Nakashima Y, Gotoh K, Mizuguchi S, Setoyama D, Takata Y, Kanno T, Kang D. Attenuating Effect of Chlorella Extract on NLRP3 Inflammasome Activation by Mitochondrial Reactive Oxygen Species Front Nutr 2021 8:763492 PubMed ID: 34692754

11608 Tsuhako R, Yoshida H, Sugita C, Kurokawa M. Naringenin suppresses neutrophil infiltration into adipose tissue in high-fat diet-induced obese mice. J Nat Med 2020 74(1):229-237. PubMed ID: 31218550

11704 Miori Tanaka, Ayako Sugama, Kanako Sumi, Kozue Shimizu, Yoshimi Kishimoto, Kazuo Kondo, Kaoruko Iida Gallic acid regulates adipocyte hypertrophy and suppresses inflammatory gene expression induced by the paracrine interaction between adipocytes and macrophages in vitro and in vivo Nutrition Research 2020 73:58-66 PubMed ID: 31841748

11757 Manabe Y, Takii Y, Sugawara T. Siphonaxanthin, a carotenoid from green algae, suppresses advanced glycation end product-induced inflammatory responses. J Nat Med 2020 74(1):127-134 PubMed ID: 31432315

11863 Yamada K, Takizawa S, Ohgaku Y, Asami T, Furuya K, Yamamoto K, Takahashi F, Hamajima C, Inaba C, Endo K, Matsui R, Kitamura H, Tanaka S. MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages. Gene 2020 PubMed ID: 31654705

6906 Shinjyo N, Nakayama H, Ishimaru K, Hikosaka K, Mi-Ichi F, Norose K, Yoshida H. Hypericum erectum alcoholic extract inhibits Toxoplasma growth and Entamoeba encystation: an exploratory study on the anti-protozoan potential. J Nat Med 2020 74(1):294-305 PubMed ID: 31728823

11900 Fujihara Y, Abe T, Asawa Y, Nishizawa S, Saijo H, Hikita A, Hoshi K. Influence of Damage-Associated Molecular Patterns from Chondrocytes in Tissue-Engineered Cartilage. Tissue Eng Part A 2020 PubMed ID: 31724485

12001 Yoshimoto Y, Jo JI, Tabata Y. Preparation of antibody-immobilized gelatin nanospheres incorporating a molecular beacon to visualize the biological function of macrophages. Regen Ther 2020 PubMed ID: 31970268

12006 Kohara Y, Haraguchi R, Kitazawa R, Kitazawa S. Knockdown of Lrp1 in RAW264 cells inhibits osteoclast differentiation and osteoclast-osteoblast interactions in vitro. Biochem. Biophys. Res. Commun. 2020 PubMed ID: 31964526

12009 Bandow K, Hasegawa H, Tomomura M, Tomomura A. Caldecrin inhibits lipopolysaccharide-induced pro-inflammatory cytokines and M1 macrophage polarization through the immunoreceptor triggering receptor expressed in myeloid cells-2. Biochem. Biophys. Res. Commun. 2020 PubMed ID: 31973822

12016 Kawakubo M, Tanaka M, Ochi K, Watanabe A, Saka-Tanaka M, Kanamori Y, Yoshioka N, Yamashita S, Goto M, Itoh M, Shirakawa I, Kanai S, Suzuki H, Sawada M, Ito A, Ishigami M, Fujishiro M, Arima H, Ogawa Y, Suganami T. Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects. Sci Rep 2020 PubMed ID: 31969650

12026 Tanaka M, Miyake H, Oka S, Maeda S, Iwasaki K, Mukai T. Effects of charged lipids on the physicochemical and biological properties of lipid-styrene maleic acid copolymer discoidal particles. Biochim Biophys Acta Biomembr 2020 PubMed ID: 32004520

12048 Funakoshi-Tago M, Nonaka Y, Tago K, Takeda M, Ishihara Y, Sakai A, Matsutaka M, Kobata K, Tamura H. Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2. Sci Rep 2020 PubMed ID: 32054966

12058 Phan TKT, Shahbazzadeh F, Kihara T. Alpha-mangostin reduces mechanical stiffness of various cells. Hum. Cell 2020 PubMed ID: 32078151

12092 Kamiya Y, Kikuchi T, Goto H, Okabe I, Takayanagi Y, Suzuki Y, Sawada N, Okabe T, Suzuki Y, Kondo S, Hayashi JI, Mitani A. IL-35 and RANKL Synergistically Induce Osteoclastogenesis in RAW264 Mouse Monocytic Cells. Int J Mol Sci 2020 PubMed ID: 32197293

12110 Uchikawa M, Kato M, Nagata A, Sanada S, Yoshikawa Y, Tsunematsu Y, Sato M, Suzuki T, Hashidume T, Watanabe K, Yoshikawa Y, Miyoshi N. Elevated levels of proinflammatory volatile metabolites in feces of high fat diet fed KK-A^y mice. Sci Rep 2020 PubMed ID: 32231228

12126 Amlabu WE, Antwi CA, Awandare G, Gwira TM. Elucidating the possible mechanism of action of some pathogen box compounds against Leishmania donovani. PLoS Negl Trop Dis 2020 PubMed ID: 32275665

12130 Sanada S, Suzuki T, Nagata A, Hashidume T, Yoshikawa Y, Miyoshi N. Intestinal microbial metabolite stercobilin involvement in the chronic inflammation of ob/ob mice. Sci Rep 2020 PubMed ID: 32296105

12171 Kazunori Sasaki, Yuri Inami, Kenichi Tominaga, Hideo Kigoshi, Takashi Arimura , and Hiroko Isoda Synthesis of 2-(2-Hydroxyethoxy)-3-hydroxysqualene and Characterization of Its Anti-Inflammatory Effects BioMed Research International 2020 PubMed ID: 32382581

10948 Karen Yotsumoto, Terukazu Sanui, Urara Tanaka, Hiroaki Yamato, Rehab Alshargabi, Takanori Shinjo, Yuki Nakao, Yukari Watanabe, Chikako Hayashi, Takaharu Taketomi, Takao Fukuda, Fusanori Nishimura Amelogenin Downregulates Interferon Gamma-Induced Major Histocompatibility Complex Class II Expression Through Suppression of Euchromatin Formation in the Class II Transactivator Promoter IV Region in Macrophages Front Immunol 2020 11:709 PubMed ID: 32373130

12488 Takeda Y, Murata T, Jamsransuren D, Suganuma K, Kazami Y, Batkhuu J, Badral D, Ogawa H. Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Viruses Including SARS-CoV-2 Viruses 2020 12(7):699 PubMed ID: 32605306

13012 Kumagai M, Nishikawa K, Mishima T, Yoshida I, Ide M, Watanabe A, Fujita K, Morimoto Y. Fluorinated Kavalactone Inhibited RANKL-Induced Osteoclast Differentiation of RAW264 Cells. Biol Pharm Bull 2020 PubMed ID: 32378565

13036 Tanaka M, Sato A, Kishimoto Y, Mabashi-Asazuma H, Kondo K, Iida K. Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes. Nutrients 2020 PubMed ID: 32443660

13065 Crentsil JA, Yamthe LRT, Anibea BZ, Broni E, Kwofie SK, Tetteh JKA, Osei-Safo D. Leishmanicidal Potential of Hardwickiic Acid Isolated From Croton sylvaticus. Front Pharmacol 2020 PubMed ID: 32523532

13097 Kim Y, Wu L, Park HC, Yang HC. Reduction of fibrous encapsulation by polyethylene glycol-grafted liposomes containing phosphatidylserine. Biomed Mater 2020 PubMed ID: 32615550

13137 Kawata R, Oda S, Koya Y, Kajiyama H, Yokoi T. Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production. Toxicology 2020 PubMed ID: 32739513

13139 Kawai K, Egami Y, Nishigaki A, Araki N. Rab35 Targeting to the Plasma Membrane Is Dependent on the C-terminal Polybasic Cluster. Acta Histochem Cytochem 2020 PubMed ID: 32873993

13146 Ertunc N, Sato C, Kitajima K. Sialic acid sulfation is induced by the antibiotic treatment in mammalian cells. Biosci Biotechnol Biochem 2020 PubMed ID: 32752946

13150 Totani H, Shinjo K, Suzuki M, Katsushima K, Mase S, Masaki A, Ito A, Ri M, Kusumoto S, Komatsu H, Ishida T, Inagaki H, Iida S, Kondo Y. Autocrine HGF/c-Met signaling pathway confers aggressiveness in lymph node adult T-cell leukemia/lymphoma. Oncogene 2020 PubMed ID: 32747750

13168 Mikami A, Ogita T, Namai F, Shigemori S, Sato T, Shimosato T. Oral administration of Flavonifractor plautii attenuates inflammatory responses in obese adipose tissue. Mol Biol Rep 2020 PubMed ID: 32808115

13180 Wada S, Kanzaki H, Katsumata Y, Yamaguchi Y, Narimiya T, Attucks OC, Nakamura Y, Tomonari H. Bach1 Inhibition Suppresses Osteoclastogenesis via Reduction of the Signaling via Reactive Oxygen Species by Reinforced Antioxidation. Front Cell Dev Biol 2020 PubMed ID: 32850850

13258 Takeuchi T, Horimoto Y, Oyama M, Nakatani S, Kobata K, Tamura M, Arata Y, Hatanaka T. Osteoclast Differentiation Is Suppressed by Increased O-GlcNAcylation Due to Thiamet G Treatment. Biol Pharm Bull 2020 PubMed ID: 32999159

13294 Nishigaki C, Nakayama M, Miyata H. Cell physiological responses of RAW264 macrophage cells to a 50-Hz magnetic field. Int J Radiat Biol 2020 PubMed ID: 33052723

13298 Yang X, Sasano T, Ebana Y, Takeuchi JK, Ihara K, Yamazoe M, Furukawa T. Functional Role of the L396R Mutation of Tks5 Identified by an Exome-Wide Association Study in Atrial Fibrillation. Circ J 2020 PubMed ID: 33087629

13324 Yahiro K, Ogura K, Goto Y, Iyoda S, Kobayashi T, Takeuchi H, Ohnishi M, Moss J. Subtilase cytotoxin induces a novel form of Lipocalin 2, which promotes Shiga-toxigenic Escherichia coli survival. Sci Rep 2020 PubMed ID: 33144618

13341 Matur M, Madhyastha H, Shruthi TS, Madhyastha R, Srinivas SP, Navya PN, Daima HK. Engineering bioactive surfaces on nanoparticles and their biological interactions. Sci Rep 2020 PubMed ID: 33184324

13434 Frederick Ayertey, Ebenezer Ofori-Attah, Stephen Antwi, Michael Amoa-Bosompem, Georgina Djameh, Nathaniel Lartey Lartey, Mistuko Ohashi, Kwadwo Asamoah Kusi, Alfred Ampomah Appiah, Regina Appiah-Opong, Laud Kenneth Okine Anti-inflammatory activity and mechanism of action of ethanolic leaf extract of Morinda lucida Benth Journal of Traditional and Complementary Medicine 2020

13492 Masanori HASHIMOTO, Haruaki KITAGAWA, Yusuke TAKAHASHI, Mikako HAYASHI, Satoshi IMAZATO Cytotoxicity of S-PRG Fillers: Direct Exposure of Fillers and Eluates from the Fillers to RAW264 Cells Nano Biomedicine 2020 12:3-10

13545 Quan H, Kim Y, Wu L, Park HC, Yang HC. Modulation of Macrophage Polarization by Phospholipids on the Surface of Titanium Molecules 2020 25(11):2700 PubMed ID: 32532146

13614 Kuramoto M, Kawashima N, Tazawa K, Nara K, Fujii M, Noda S, Hashimoto K, Nozaki K, Okiji T. Mineral trioxide aggregate suppresses pro-inflammatory cytokine expression via the calcineurin/nuclear factor of activated T cells/early growth response 2 pathway in lipopolysaccharide-stimulated macrophages Int Endod J 2020 53(12):1653-1665 PubMed ID: 32767860

13633 Lu DZ, Dong W, Feng XJ, Chen H, Liu JJ, Wang H, Zang LY, Qi MC. CaMKII(δ) regulates osteoclastogenesis through ERK, JNK, and p38 MAPKs and CREB signalling pathway Mol Cell Endocrinol 2020 508:110791 PubMed ID: 32173349

13639 Nishiguchi A, Taguchi T. Development of an immunosuppressive camouflage-coating platform with nanocellulose and cell membrane vesicles J Biomater Sci Polym Ed 2020 31(15):1912-1924 PubMed ID: 32538290

13643 Nishiguchi A, Taguchi T. Sustained-immunostimulatory nanocellulose scaffold to enhance vaccine efficacy J Biomed Mater Res A 2020 108(5):1159-1170 PubMed ID: 31990447

13906 Ide M, Yoshida I, Kumagai M, Mishima T, Takahashi Y, Fujita K, Igarashi T, Matsuura E. Tithonia diversifolia-derived orizabin suppresses cell adhesion, differentiation, and oxidized LDL accumulation by Akt signaling suppression via PTEN promotion in THP-1 cells J Food Biochem 2020 44(7):e13268 PubMed ID: 32412116

15459 Koga M, Kanaoka Y, Okamoto M, Nakao Y, Inada K, Takayama S, Kataoka Y, Yamauchi A. Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression J Pharmacol Sci 2020 142(1):9-15 PubMed ID: 31771811

16615 Aki T, Funakoshi T, Noritake K, Unuma K, Uemura K. Extracellular glucose is crucially involved in the fate decision of LPS-stimulated RAW264.7 murine macrophage cells Sci Rep 2020 10(1):10581 PubMed ID: 32601294

16816 Chie Kojima, Risa Katayama, Thi Lien Nguyen, Yuto Oki, Ayako Tsujimoto, Shin-ichi Yusa, Kohei Shiraishi, Akikazu Matsumoto Different antifouling effects of random and block copolymers comprising 2-methacryloyloxyethyl phosphorylcholine and dodecyl methacrylate European Polymer Journal 2020 136:109932

16824 Natsuki Hayakawa, Takuya Yamada, Yukiya Kitayama, Toshifumi Takeuchi Cellular Interaction Regulation by Protein Corona Control of Molecularly Imprinted Polymer Nanogels Using Intrinsic Proteins ACS Applied Polymer Materials 2020 2:1465-1473

11167 Chaweewannakorn W, Ariyoshi W, Okinaga T, Fujita Y, Maki K, Nishihara T. Ameloblastin attenuates RANKL-mediated osteoclastogenesis by suppressing activation of nuclear factor of activated T-cell cytoplasmic 1 (NFATc1). J. Cell. Physiol. 2019 234(2):1745-175 PubMed ID: 30105896

11173 Madhyastha R, Madhyastha H, Pengjam Y, Nurrahmah QI, Nakajima Y, Maruyama M. The pivotal role of microRNA-21 in osteoclastogenesis inhibition by anthracycline glycoside aloin. J Nat Med 2019 73(1):59-66 PubMed ID: 30116953

11279 Sun S, Li K, Xiao L, Lei Z, Zhang Z. Characterization of polysaccharide from Helicteres angustifolia L. and its immunomodulatory activities on macrophages RAW264.7. Biomed. Pharmacother. 2019 PubMed ID: 30396084

11335 Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Ando K, Tanimoto K. The effect of mesenchymal stem cells on osteoclast precursor cell differentiation. J Oral Sci 2019 PubMed ID: 30541990

11361 Islam Z, Inui T, Ishibashi O. Gpr137b is an orphan G-protein-coupled receptor associated with M2 macrophage polarization. Biochem. Biophys. Res. Commun. 2019 PubMed ID: 30595385

11380 Nemoto R, Fujieda K, Hiruta Y, Hishida M, Ayano E, Maitani Y, Nagase K, Kanazawa H. Liposomes with temperature-responsive reversible surface properties. Colloids Surf B Biointerfaces 2019 PubMed ID: 30641302

11396 Yoshinaga N, Uchida S, Naito M, Osada K, Cabral H, Kataoka K. Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection. Biomaterials 2019 PubMed ID: 30669016

11383 Manabe Y, Hirata T, Sugawara T. Inhibitory Effect of Carotenoids on Ligand-induced Lipid Raft Translocation of Immunoreceptors. J Oleo Sci 2019 PubMed ID: 30651415

11389 Wang W, Nakashima KI, Hirai T, Inoue M. Anti-inflammatory effects of naturally occurring retinoid X receptor agonists isolated from Sophora tonkinensis Gagnep. via retinoid X receptor/liver X receptor heterodimers. J Nat Med 2019 PubMed ID: 30656541

11457 Takahashi S, Yoshida M, Watanabe MM, Isoda H. Anti-Inflammatory Effects of Aurantiochytrium limacinum 4W-1b Ethanol Extract on Murine Macrophage RAW264 Cells. Biomed Res Int 2019 PubMed ID: 30809537

11437 Yanagihara Y, Inoue K, Saeki N, Sawada Y, Yoshida S, Lee J, Iimura T, Imai Y. Zscan10 suppresses osteoclast differentiation by regulating expression of Haptoglobin. Bone 2019 PubMed ID: 30771488

11454 Antwi CA, Amisigo CM, Adjimani JP, Gwira TM. In vitro activity and mode of action of phenolic compounds on Leishmania donovani. PLoS Negl Trop Dis 2019 PubMed ID: 30802252

11477 Zhang T, Ono K, Tsutsuki H, Ihara H, Islam W, Akaike T, Sawa T. Enhanced Cellular Polysulfides Negatively Regulate TLR4 Signaling and Mitigate Lethal Endotoxin Shock. Cell Chem Biol 2019 PubMed ID: 30853417

5357 Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell 2019 76(5):797-810 PubMed ID: 31606272

11498 Narita Y, Shimizu K, Ikemoto K, Uchino R, Kosugi M, Maess MB, Magata Y, Oku N, Ogawa M. Macrophage-targeted, enzyme-triggered fluorescence switch-on system for detection of embolism-vulnerable atherosclerotic plaques. J Control Release 2019 PubMed ID: 30936020

11508 Saito H, Tanaka T, Sugahara M, Tanaka S, Fukui K, Wakashima T, Nangaku M. Inhibition of prolyl hydroxylase domain (PHD) by JTZ-951 reduces obesity-related diseases in the liver, white adipose tissue, and kidney in mice with a high-fat diet. Lab. Invest. 2019 PubMed ID: 30952940

11539 Suzuka H, Mimura A, Inaoka Y, Murase K. Magnetic Nanoparticles in Macrophages and Cancer Cells Exhibit Different Signal Behavior on Magnetic Particle Imaging. J Nanosci Nanotechnol 2019 PubMed ID: 31039837

11604 Miyazaki Y, Iwaihara Y, Bak J, Nakano H, Takeuchi S, Takeuchi H, Matsui T, Tachikawa D. The cooperative induction of macrophage activation by fucoidan derived from Cladosiphon okamuranus and β-glucan derived from Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 2019 PubMed ID: 31221482

11617 Takeuchi T, Koinuma S, Yokosawa H, Arata Y. An Approach for the Identification of Proteins Modified with ISG15. Methods Mol. Biol. 2019 PubMed ID: 31256383

11736 Wang X, Batubara I, Yamauchi K, Mitsunaga T. Identification and structure-activity relationship (SAR) of chemical constituents from Daemonorops draco (Willd.) Blume and selected commercial flavonoids on anti-osteoclastogenesis activity. Fitoterapia 2019 PubMed ID: 31376421

11772 Okuda-Hanafusa C, Uchio R, Fuwa A, Kawasaki K, Muroyama K, Yamamoto Y, Murosaki S. Turmeronol A and turmeronol B from Curcuma longa prevent inflammatory mediator production by lipopolysaccharide-stimulated RAW264.7 macrophages, partially via reduced NF-κB signaling. Food Funct 2019 PubMed ID: 31454011

11780 Tan H, Zhao C, Zhu Q, Katakura Y, Tanaka H, Ohnuki K, Shimizu K. Ursolic Acid Isolated from the Leaves of Loquat ( Eriobotrya japonica) Inhibited Osteoclast Differentiation through Targeting Exportin 5. J. Agric. Food Chem. 2019 PubMed ID: 30827108

11793 Mizuno Y, Taguchi T. Growth factor-free, angiogenic hydrogel based on hydrophobically modified Alaska pollock gelatin. J Tissue Eng Regen Med 2019 PubMed ID: 31503405

11801 Ueta M, Takaoka K, Yamamura M, Maeda H, Tamaoka J, Nakano Y, Noguchi K, Kishimoto H. Effects of TGF‑β1 on the migration and morphology of RAW264.7 cells in vitro. Mol Med Rep 2019 PubMed ID: 31545488

11810 Ara T, Koide M, Kitamura H, Sogawa N. Effects of shokyo (Zingiberis Rhizoma) and kankyo (Zingiberis Processum Rhizoma) on prostaglandin E2 production in lipopolysaccharide-treated mouse macrophage RAW264.7 cells. PeerJ 2019 PubMed ID: 31576251

11873 Ju N, Shimamura M, Hayashi H, Ikeda Y, Yoshida S, Nakamura A, Morishita R, Rakugi H, Nakagami H. Preventative effects of the partial RANKL peptide MHP1-AcN in a mouse model of imiquimod-induced psoriasis. Sci Rep 2019 PubMed ID: 31659208

6944 Yo S, Hamamura K, Mishima Y, Hamajima K, Mori H, Furukawa K, Kondo H, Tanaka K, Sato T, Miyazawa K, Goto S, Togari A. Deficiency of GD3 Synthase in Mice Resulting in the Attenuation of Bone Loss with Aging. Int J Mol Sci 2019 20(11):2825 PubMed ID: 31185614

9468 Kazuyo Fujita, Masaharu Somiya, Shun'ichi Kuroda, Shuji Hinuma Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes Biochem Biophys Res Commun 2019 510(1):184-190 PubMed ID: 30678809

10512 Sayumi Yamada et al Anti-Inflammatory and Antimicrobial Activities of Aqueous Extracts of Wild Mushrooms from Japan International Journal of Medicinal Mushrooms 2019 21:469-486

10763 Ahmed Elkhateeb, Mona El-Shabrawy, Rehab F. Abdel-Rahman, Mona M. Marzouk, Ahmed H. El-Desoky, El-Sayed S. Abdel-Hameed & Sameh R. Hussein LC-MS-based metabolomic profiling of Lepidium coronopus water extract, anti-inflammatory and analgesic activities, and chemosystematic significance Medicinal Chemistry Research 2019 28:505–514

10848 X.YangaZ.Lei, Y.YuaL.Xiao, D.Cheng, Z.Zhang Phytochemical characteristics of callus suspension culture of Helicteres angustifolia L. and its in vitro antioxidant, antidiabetic and immunomodulatory activities South African Journal of Botany 2019 121:178-185

11886 Ali MFZ, Ohta T, Ido A, Miura C, Miura T. The Dipterose of Black Soldier Fly (Hermetia illucens) Induces Innate Immune Response through Toll-Like Receptor Pathway in Mouse Macrophage RAW264.7 Cells. Biomolecules 2019 PubMed ID: 31683715

11908 Pavillon N, Smith NI. Immune cell type, cell activation, and single cell heterogeneity revealed by label-free optical methods. Sci Rep 2019 PubMed ID: 31745140

11914 Shimakura H, Gen-Nagata F, Haritani M, Furusaki K, Kato Y, Yamashita-Kawanishi N, LE DT, Tsuzuki M, Tohya Y, Kyuwa S, Saito H, Horimoto T, Onodera T, Haga T. Inactivation of human norovirus and its surrogate by the disinfectant consisting of calcium hydrogen carbonate mesoscopic crystals. FEMS Microbiol. Lett. 2019 PubMed ID: 31758686

11948 Yamashiro T, Yasujima T, Ohta K, Inoue K, Yuasa H. Identification of the amino acid residue responsible for the myricetin sensitivity of human proton-coupled folate transporter. Sci Rep 2019 PubMed ID: 31792273

12316 Kitazawa R, Kinto-Shibahara S, Haraguchi R, Kohara Y, Kitazawa S. Activation of protein kinase C accelerates murine osteoclastogenesis partly via transactivation of RANK gene through functional AP-1 responsive element in RANK gene promoter Biochem Biophys Res Commun 2019 515(2):268-274 PubMed ID: 31146918

12336 Sakakura A, Pauze M, Namiki A, Funakoshi-Tago M, Tamura H, Hanaya K, Higashibayashi S, Sugai T. Chemoenzymatic synthesis of hydroxytyrosol monoesters and their suppression effect on nitric oxide production stimulated by lipopolysaccharides Biosci Biotechnol Biochem 2019 83(2):185-191 PubMed ID: 30319060

12555 Islam Z, Horikawa A, Inui T, Ishibashi O. Datasets of microarray analysis to identify Gpr137b-dependent interleukin-4-responsive genes in the mouse macrophage cell line RAW264 Data Brief 2019 23:103669 PubMed ID: 31372377

12556 Saiki P, Kawano Y, Nakajima Y, Van Griensven LJLD, Miyazaki K. Reporters Derived from RAW 264.7 for Anti-Inflammation Screening of Natural Products Int J Mol Sci 2019 20(18):4620 PubMed ID: 31540402

12557 Kono Y, Gogatsubo S, Ohba T, Fujita T. Enhanced macrophage delivery to the colon using magnetic lipoplexes with a magnetic field Drug Deliv 2019 26(1):935-943 PubMed ID: 31530198

12559 Li F, Kitajima S, Kohno S, Yoshida A, Tange S, Sasaki S, Okada N, Nishimoto Y, Muranaka H, Nagatani N, Suzuki M, Masuda S, Thai TC, Nishiuchi T, Tanaka T, Barbie DA, Mukaida N, Takahashi C. Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion Cancer Res 2019 79(15):3903-3915 PubMed ID: 31189648

12978 Kojima C, Narita Y, Nakajima Y, Morimoto N, Yoshikawa T, Takahashi N, Handa A, Waku T, Tanaka N. Modulation of Cell Adhesion and Differentiation on Collagen Gels by the Addition of the Ovalbumin Secretory Signal Peptide. ACS Biomater Sci Eng 2019 PubMed ID: 33405701

15292 Nagata J, Yokodera H, Maeda G. In Vitro and in Vivo Studies on Anti-Inflammatory Effects of Traditional Okinawan Vegetable Methanol Extracts ACS Omega 2019 4(13):15660-15664 PubMed ID: 31572868

10342 Fujihara Y, Hikita A, Takato T, Hoshi K. Roles of macrophage migration inhibitory factor in cartilage tissue engineering. J. Cell. Physiol. 2018 233:1490-1499 PubMed ID: 28574571

10432 Tokuyama-Nakai S, Kimura H, Ishihara T, Jisaka M, Yokota K. In Vitro Anti-inflammatory and Antioxidant Activities of 3,5,4'-Trihydroxy-6,7-Methylenedioxyflavone-O-Glycosides and Their Aglycone from Leaves of Polygonum tinctorium Lour. Appl. Biochem. Biotechnol. 2018 184:414-431 PubMed ID: 28721651

10557 Elfeky M, Yoneshiro T, Okamatsu-Ogura Y, Kimura K. Adiponectin suppression of late inflammatory mediator, HMGB1-induced cytokine expression in RAW264 macrophage cells. J. Biochem. 2018 163:143-153 PubMed ID: 29048484

10569 Yamaguchi Y, Kanzaki H, Katsumata Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y. Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation. J. Cell. Mol. Med. 2018 22:1138-1147 PubMed ID: 29063666

10614 Stockler-Pinto MB, Soulage CO, Borges NA, Cardozo LFMF, Dolenga CJ, Nakao LS, Pecoits-Filho R, Fouque D, Mafra D. From bench to the hemodialysis clinic: protein-bound uremic toxins modulate NF-κB/Nrf2 expression. Int Urol Nephrol 2018 50:347-354 PubMed ID: 29151180

10645 Nagahara H, Seno T, Yamamoto A, Obayashi H, Inoue T, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y. Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis. Biochem. Biophys. Res. Commun. 2018 495:1901-1907 PubMed ID: 29225172

10696 Kumagai M, Watanabe A, Yoshida I, Mishima T, Nakamura M, Nishikawa K, Morimoto Y. Evaluation of Aculeatin and Toddaculin Isolated from Toddalia asiatica as Anti-inflammatory Agents in LPS-Stimulated RAW264 Macrophages. Biol. Pharm. Bull. 2018 41:132-137 PubMed ID: 29311475

10708 Kon R, Tsubota Y, Minami M, Kato S, Matsunaga Y, Kimura H, Murakami Y, Fujikawa T, Sakurai R, Tomimoto R, Machida Y, Ikarashi N, Sugiyama K. CPT-11-Induced Delayed Diarrhea Develops via Reduced Aquaporin-3 Expression in the Colon. Int J Mol Sci 2018 19: PubMed ID: 29316651

10711 Egami Y, Araki N. Transient recruitment of M-Ras GTPase to phagocytic cups in RAW264 macrophages during FcγR-mediated phagocytosis. Microscopy (Oxf) 2018 67:68-74 PubMed ID: 29340604

10714 Tsukayama I, Toda K, Takeda Y, Mega T, Tanaka M, Kawakami Y, Takahashi Y, Kimoto M, Yamamoto K, Miki Y, Murakami M, Suzuki-Yamamoto T. Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway. J Clin Biochem Nutr 2018 62:139-147 PubMed ID: 29610553

10782 Miyashita T, Minami K, Ito M, Koizumi R, Sagane Y, Watanabe T, Niwa K. Emu Oil Reduces LPS-Induced Production of Nitric Oxide and TNF-α but not Phagocytosis in RAW 264 Macrophages. J Oleo Sci 2018 67:471-477 PubMed ID: 29526880

10790 El-Desoky AH, Abdel-Rahman RF, Ahmed OK, El-Beltagi HS, Hattori M. Anti-inflammatory and antioxidant activities of naringin isolated from Carissa carandas L.: In vitro and in vivo evidence. Phytomedicine 2018 42:126-134 PubMed ID: 29655678

10799 Kawai C, Yamauchi A, Kuribayashi F. Monoclonal antibody 7D5 recognizes the R147 epitope on the gp91phox , phagocyte flavocytochrome b558 large subunit. Microbiol. Immunol. 2018 62:269-280 PubMed ID: 29573449

11027 Miyake T, Miyake T, Sakaguchi M, Nankai H, Nakazawa T, Morishita R. Prevention of Asthma Exacerbation in a Mouse Model by Simultaneous Inhibition of NF-kB and STAT6 Activation Using a Chimeric Decoy Strategy Mol Ther Nucleic Acids 2018 10:159-169 PubMed ID: 29499930

11198 Ikebuchi Y, Aoki S, Honma M, Hayashi M, Sugamori Y, Khan M, Kariya Y, Kato G, Tabata Y, Penninger JM, Udagawa N, Aoki K, Suzuki H. Coupling of bone resorption and formation by RANKL reverse signalling. Nature 2018 561(7722):195-200 PubMed ID: 30185903

4050 Mukai Y, Yamanishi R. Retinol but not retinoic acid can enhance the glutathione level, in a manner similar to β-carotene, in a murine cultured macrophage cell line. Food Sci Nutr 2018 PubMed ID: 30258608

11098 Ali MFZ, Yasin IA, Ohta T, Hashizume A, Ido A, Takahashi T, Miura C, Miura T. The silkrose of Bombyx mori effectively prevents vibriosis in penaeid prawns via the activation of innate immunity. Sci Rep 2018 8(1):8836 PubMed ID: 29892000

11116 Tasaka T, Kuwada E, Izuchi Y, Nishigawa R, Yamada H, Unuma H, Tokunaga K, Hayakawa A, Go A, Go K, Uto Y. Concentration-dependent Activation of Inflammatory/Anti-inflammatory Functions of Macrophages by Hydrolyzed Whey Protein. Anticancer Res. 2018 38(7):4299-4304 PubMed ID: 29970565

11122 Sakoda M, Kaneko M, Ohta S, Qi P, Ichimura S, Yatomi Y, Ito T. Injectable Hemostat Composed of a Polyphosphate-Conjugated Hyaluronan Hydrogel. Biomacromolecules 2018 19(8):3280-3290 PubMed ID: 29985587

11186 Kawasaki K, Okuda-Hanafusa C, Aoyagi M, Taoka K, Yamamoto N, Muroyama K, Murosaki S, Yamamoto Y. Inhibitory effect of the compounds from the water extract of Curcuma longa on the production of PGE2 and NO in a macrophage cell line stimulated by LPS. Biosci. Biotechnol. Biochem. 2018 82(12):2109-2117 PubMed ID: 30146952

11200 Odkhuu E, Komatsu T, Koide N, Naiki Y, Takeuchi K, Tanaka Y, Tsolmongyn B, Jambalganiin U, Morita N, Yoshida T, Gotoh B, Yokochi T. Sendai virus C protein limits NO production in infected RAW264.7 macrophages. Innate Immun 2018 24(7):430-438 PubMed ID: 30189760

11074 Tsukamoto H, Takeuchi S, Kubota K, Kobayashi Y, Kozakai S, Ukai I, Shichiku A, Okubo M, Numasaki M, Kanemitsu Y, Matsumoto Y, Nochi T, Watanabe K, Aso H, Tomioka Y. Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKK?-IRF3 axis activation. J. Biol. Chem. 2018 293(26):10186-10201 PubMed ID: 29760187

11112 Niino T, Tago K, Yasuda D, Takahashi K, Mashino T, Tamura H, Funakoshi-Tago M. A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis. Biochem. Pharmacol. 2018 155:182-197 PubMed ID: 29940171

11249 Kamiya T, Tanimoto Y, Fujii N, Negishi T, Suzuki T, Hatano T, Arimoto-Kobayashi S. 2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae. Food Chem. Toxicol. 2018 PubMed ID: 30316843

11493 Katsumata Y, Kanzaki H, Honda Y, Tanaka T, Yamaguchi Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y. Single Local Injection of Epigallocatechin Gallate-Modified Gelatin Attenuates Bone Resorption and Orthodontic Tooth Movement in Mice. Polymers (Basel) 2018 10(12) PubMed ID: 30961309

11349 Sugiyama Y, Hiraiwa Y, Hagiya Y, Nakajima M, Tanaka T, Ogura SI. 5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW 264.7 macrophages. BMC Immunol. 2018 PubMed ID: 30567499

4441 Seisho Azuma, Yoshinobu Murakami, Eiko Azuma, Kimiye Baba, Masahiko Taniguchi Anti-inflammatory effects of flavonoids in Citrus jabara fruit peels Trends in Immunotherapy 2018 2

4324 Quan H, Kim Y, Park HC, Yang HC. Effects of phosphatidylserine-containing supported lipid bilayers on the polarization of macrophages. J Biomed Mater Res A 2018 PubMed ID: 29781181

4325 Hoshi K, Yamazaki T, Yoshikawa C, Tsugawa W, Ikebukuro K, Sode K. Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production. Int J Nanomedicine 2018 PubMed ID: 30122920

4326 Saiki P, Nakajima Y, Van Griensven LJLD, Miyazaki K. Real-time monitoring of IL-6 and IL-10 reporter expression for anti-inflammation activity in live RAW 264.7 cells. Biochem. Biophys. Res. Commun. 2018 PubMed ID: 30301531

4327 Abe T, Sumi K, Kunimatsu R, Oki N, Tsuka Y, Nakajima K, Tanimoto K. Dynamic imaging of the effect of mesenchymal stem cells on osteoclast precursor cell chemotaxis for bone defects in the mouse skull. J Dent Sci 2018 PubMed ID: 30895145

4328 Sumi K, Abe T, Kunimatsu R, Oki N, Tsuka Y, Awada T, Nakajima K, Ando K, Tanimoto K. The effect of mesenchymal stem cells on chemotaxis of osteoclast precursor cells. J Oral Sci 2018 PubMed ID: 29925706

4329 Kajita T, Ariyoshi W, Okinaga T, Mitsugi S, Tominaga K, Nishihara T. Mechanisms involved in enhancement of osteoclast formation by activin-A. J. Cell. Biochem. 2018 PubMed ID: 29737562

4330 Sakamoto T, Ohashi W, Tomita K, Hattori K, Matsuda N, Hattori Y. Anti-inflammatory properties of cilostazol: Its interruption of DNA binding activity of NF-κB from the Toll-like receptor signaling pathways. Int. Immunopharmacol. 2018 PubMed ID: 30005227

4331 El-Beih AA, El-Desoky AH, Al-Hammady MA, Elshamy AI, Hegazy MF, Kato H, Tsukamoto S. New inhibitors of RANKL-induced Osteoclastogenesis from the marine sponge Siphonochalina siphonella. Fitoterapia 2018 PubMed ID: 29729401

4332 Tanaka M, Kishimoto Y, Sasaki M, Sato A, Kamiya T, Kondo K, Iida K. Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways. Oxid Med Cell Longev 2018 PubMed ID: 30533177

4333 Kawabata K, Baba N, Sakano T, Hamano Y, Taira S, Tamura A, Baba S, Natsume M, Ishii T, Murakami S, Ohigashi H. Functional properties of anti-inflammatory substances from quercetin-treated Bifidobacterium adolescentis. Biosci. Biotechnol. Biochem. 2018 PubMed ID: 29165050

4334 Fukai E, Sato H, Watanabe M, Nakae D, Totsuka Y. Establishment of an in vivo simulating co-culture assay platform for genotoxicity of multi-walled carbon nanotubes. Cancer Sci. 2018 PubMed ID: 29444368

4335 Hussain Z, Uyama T, Kawai K, Binte Mustafiz SS, Tsuboi K, Araki N, Ueda N. Phosphatidylserine-stimulated production of N-acyl-phosphatidylethanolamines by Ca2+-dependent N-acyltransferase. Biochim Biophys Acta Mol Cell Biol Lipids 2018 PubMed ID: 29447909

4336 Takahashi S, Sakamaki M, Ferdousi F, Yoshida M, Demura M, Watanabe MM, Isoda H. Ethanol Extract of Aurantiochytrium mangrovei 18W-13a Strain Possesses Anti-inflammatory Effects on Murine Macrophage RAW264 Cells. Front Physiol 2018 PubMed ID: 30319432

4496 Su YW, Chim SM, Zhou L, Hassanshahi M, Chung R, Fan C, Song Y, Foster BK, Prestidge CA, Peymanfar Y, Tang Q, Butler LM, Gronthos S, Chen D, Xie Y, Chen L, Zhou XF, Xu J, Xian CJ. Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats. Bone 2018 116:232-247 PubMed ID: 30125729

4497 Kuroda C, Ueda K, Haniu H, Ishida H, Okano S, Takizawa T, Sobajima A, Kamanaka T, Yoshida K, Okamoto M, Tsukahara T, Matsuda Y, Aoki K, Kato H, Saito N. Different aggregation and shape characteristics of carbon materials affect biological responses in RAW264 cells. Int J Nanomedicine 2018 13:6079-6088 PubMed ID: 30323595

4498 Momozane T, Kawamura T, Itoh Y, Sanosaka M, Sasaki T, Kanzaki R, Ose N, Funaki S, Shintani Y, Minami M, Okumura M, Takemori H. Carnosol suppresses interleukin-6 production in mouse lungs injured by ischemia-reperfusion operation and in RAW264.7 macrophages treated with lipopolysaccharide. Biochem. Cell Biol. 2018 96(6):769-776 PubMed ID: 29958095

4499 Choodej S, Pudhom K, Mitsunaga T. Inhibition of TNF-α-Induced Inflammation by Sesquiterpene Lactones from Saussurea lappa and Semi-Synthetic Analogues. Planta Med. 2018 84(5):329-335 PubMed ID: 28962049

14915 Komatsu W, Kishi H, Yagasaki K, Ohhira S. Urolithin A attenuates pro-inflammatory mediator production by suppressing PI3-K/Akt/NF-κB and JNK/AP-1 signaling pathways in lipopolysaccharide-stimulated RAW264 macrophages: Possible involvement of NADPH oxidase-derived reactive oxygen species Eur J Pharmacol 2018 833:411-424 PubMed ID: 29932926

15294 Pavillon N, Hobro AJ, Akira S, Smith NI. Noninvasive detection of macrophage activation with single-cell resolution through machine learning Proc Natl Acad Sci U S A 2018 115(12):E2676-E2685 PubMed ID: 29511099

7036 Komiya C, Tanaka M, Tsuchiya K, Shimazu N, Mori K, Furuke S, Miyachi Y, Shiba K, Yamaguchi S, Ikeda K, Ochi K, Nakabayashi K, Hata KI, Itoh M, Suganami T, Ogawa Y. Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis. Sci Rep 2017 7:44754 PubMed ID: 28303974

9723 Iwazaki K, Tanaka T, Hozumi Y, Okada M, Tsuchiya R, Iseki K, Topham MK, Kawamae K, Takagi M, Goto K. DGKζ Downregulation Enhances Osteoclast Differentiation and Bone Resorption Activity Under Inflammatory Conditions. J. Cell. Physiol. 2017 232:617-624 PubMed ID: 27312515

9944 Kanzaki H, Shinohara F, Itohiya K, Yamaguchi Y, Katsumata Y, Matsuzawa M, Fukaya S, Miyamoto Y, Wada S, Nakamura Y. RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice. FASEB J. 2017 31:781-792 PubMed ID: 27836987

9964 Shirasugi M, Nishioka K, Yamamoto T, Nakaya T, Kanamura N. Normal human gingival fibroblasts undergo cytostasis and apoptosis after long-term exposure to butyric acid. Biochem. Biophys. Res. Commun. 2017 482:1122-1128 PubMed ID: 27914813

10001 Quan H, Park HC, Kim Y, Yang HC. Modulation of the anti-inflammatory effects of phosphatidylserine-containing liposomes by PEGylation. J Biomed Mater Res A 2017 105:1479-1486 PubMed ID: 27998010

10074 Takano A, Fukuda T, Shinjo T, Iwashita M, Matsuzaki E, Yamamichi K, Takeshita M, Sanui T, Nishimura F. Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation. Metab. Clin. Exp. 2017 69:157-170 PubMed ID: 28285646

10085 Ariyoshi W, Okinaga T, Chaweewannakorn W, Akifusa S, Nisihara T. Mechanisms involved in enhancement of matrix metalloproteinase-9 expression in macrophages by interleukin-33. J. Cell. Physiol. 2017 232:3481-3495 PubMed ID: 28105703

10122 Taniguchi M, Ochiai A, Toyoda R, Sato T, Saitoh E, Kato T, Tanaka T. Effects of arginine and leucine substitutions on anti-endotoxic activities and mechanisms of action of cationic and amphipathic antimicrobial octadecapeptide from rice α-amylase. J. Pept. Sci. 2017 23:252-260 PubMed ID: 28185358

10165 Takeuchi T, Sugimoto A, Imazato N, Tamura M, Nakatani S, Kobata K, Arata Y. Glucosamine Suppresses Osteoclast Differentiation through the Modulation of Glycosylation Including O-GlcNAcylation. Biol. Pharm. Bull. 2017 40:352-356 PubMed ID: 28250278

10169 Zhang J, Hiromoto S, Yamazaki T, Huang H, Jia G, Li H, Yuan G. Macrophage phagocytosis of biomedical Mg alloy degradation products prepared by electrochemical method. Mater Sci Eng C Mater Biol Appl 2017 75:1178-1183 PubMed ID: 28415404

10190 Ichimura K, Shimizu T, Matsumoto A, Hirai S, Yokoyama E, Takeuchi H, Yahiro K, Noda M. Nitric oxide-enhanced Shiga toxin production was regulated by Fur and RecA in enterohemorrhagic Escherichia coli O157. Microbiologyopen 2017 6: PubMed ID: 28294553

10215 Yamagata Y, Tomioka H, Sakamoto K, Sato K, Harada H, Ikeda T, Kayamori K. CD163-Positive Macrophages Within the Tumor Stroma Are Associated With Lymphangiogenesis and Lymph Node Metastasis in Oral Squamous Cell Carcinoma. J. Oral Maxillofac. Surg. 2017 75:2144-2153 PubMed ID: 28399391

10230 Hashiguchi A, Hitachi K, Zhu W, Tian J, Tsuchida K, Komatsu S. Mung bean (Vigna radiata (L.)) coat extract modulates macrophage functions to enhance antigen presentation: A proteomic study. J Proteomics 2017 161:26-37 PubMed ID: 28373035

10285 Fereig RM, Kuroda Y, Terkawi MA, Mahmoud ME, Nishikawa Y. Immunization with Toxoplasma gondii peroxiredoxin 1 induces protective immunity against toxoplasmosis in mice. PLoS ONE 2017 12:e0176324 PubMed ID: 28448521

10288 Kato T, Toyooka T, Ibuki Y, Masuda S, Watanabe M, Totsuka Y. Effect of physicochemical character differences on the genotoxic potency of kaolin. Genes Environ 2017 39:12 PubMed ID: 28469735

10335 Wu S, Yano S, Chen J, Hisanaga A, Sakao K, He X, He J, Hou DX. Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-Induced Inflammation through Dual Modulation of Inflammatory and Antioxidant Mediators. J. Agric. Food Chem. 2017 65:5133-5141 PubMed ID: 28573848

10380 Murata K, Motomura Y, Tanaka T, Kanno S, Yano T, Onimaru M, Shimoyama A, Nishio H, Sakai Y, Oh-Hora M, Hara H, Fukase K, Takada H, Masuda S, Ohga S, Yamasaki S, Hara T. Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease. Clin. Exp. Immunol. 2017 190:54-67 PubMed ID: 28640392

10551 Saiki P, Kawano Y, Van Griensven LJLD, Miyazaki K. The anti-inflammatory effect of Agaricus brasiliensis is partly due to its linoleic acid content. Food Funct 2017 8:4150-4158 PubMed ID: 29022634

10704 Hanagata N, Li X, Chen MH, Li J, Hattori S. Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities. Int J Nanomedicine 2017 13:43-62 PubMed ID: 29317815

10915 Effect of Particle Size of Gold Nanoparticles on Matrix Metalloprotease Inhibition, Cytotoxicity and Genotoxicity Journal of Biomaterials and Tissue Engineering, 2017 7, 139-146

10949 Effect of 50-Hz Sinusoidal Magnetic Field on the Production of Superoxide Anion and the Expression of Heat-shock Protein 70 in RAW264 Cells International Journal of Chemistry 2017 9

4526 Yusuke Hiraku, Yoshihiro Nishikawa, Ning Ma, Tahmina Afroza, Kosuke Mizobuchi, Ryo Ishiyama, Yuta Matsunaga, Takamichi Ichinose, Shosuke Kawanishi, Mariko Murata Nitrative DNA damage induced by carbon-black nanoparticles in macrophages and lung epithelial cells Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2017 818, 7-16 PubMed ID: 28477879

6471 Horigome S, Yoshida I, Ito S, Inohana S, Fushimi K, Nagai T, Yamaguchi A, Fujita K, Satoyama T, Katsuda SI, Suzuki S, Watai M, Hirose N, Mitsue T, Shirakawa H, Komai M. Inhibitory effects of Kaempferia parviflora extract on monocyte adhesion and cellular reactive oxygen species production in human umbilical vein endothelial cells. Eur J Nutr 2017 56(3):949-964 PubMed ID: 26704713

9460 Nan Ma, Di Yang, Hirohiko Okamura, Jumpei Teramachi, Tomokazu Hasegawa, Lihong Qiu, Tatsuji Haneji Involvement of interleukin‑23 Induced by Porphyromonas Endodontalis Lipopolysaccharide in Osteoclastogenesis Mol Med Rep 2017 15(2):559-566 PubMed ID: 28000855

10050 Ha-Eun Yang, Yongjia Li, Akira Nishimura, Huei-Fen Jheng, Ana Yuliana, Ryuji Kitano-Ohue, Wataru Nomura, Nobuyuki Takahashi, Chu-Sook Kim, Rina Yu, Nahoko Kitamura, Si-Bum Park, Shigenobu Kishino, Jun Ogawa, Teruo Kawada, Tsuyoshi Goto Synthesized Enone Fatty Acids Resembling Metabolites From Gut Microbiota Suppress Macrophage-Mediated Inflammation in Adipocytes Mol Nutr Food Res 2017 Oct;61(10) PubMed ID: 28544341

10076 Yusuke Kono, Taketo Nakai, Hitomi Taguchi, Takuya Fujita Development of Magnetic Anionic Liposome/Atelocollagen Complexes for Efficient Magnetic Drug Targeting Drug Deliv 2017 24(1):1740-1749 PubMed ID: 29141461

12320 Masayori Hagimori, Eri Hatabe, Kohei Sano, Hirotaka Miyazaki, Hitoshi Sasaki, Hideo Saji, Takahiro Mukai An Activatable Fluorescent γ-Polyglutamic Acid Complex for Sentinel Lymph Node Imaging Biol Pharm Bull 2017 40(3):297-302 PubMed ID: 28250270

14213 Into T, Horie T, Inomata M, Gohda J, Inoue JI, Murakami Y, Niida S. Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88 Sci Rep 2017 7(1):1009 PubMed ID: 28432355

14216 Horiuchi T, Sakata N, Narumi Y, Kimura T, Hayashi T, Nagano K, Liu K, Nishibori M, Tsukita S, Yamada T, Katagiri H, Shirakawa R, Horiuchi H. Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity J Biol Chem 2017 292(20):8436-8446 PubMed ID: 28373282

14220 Wang J, Ayano E, Maitani Y, Kanazawa H. Tunable Surface Properties of Temperature-Responsive Polymer-Modified Liposomes Induce Faster Cellular Uptake ACS Omega 2017 ;2(1):316-325 PubMed ID: 31457232

14255 Komatsu W, Itoh K, Akutsu S, Kishi H, Ohhira S. Nasunin inhibits the lipopolysaccharide-induced pro-inflammatory mediator production in RAW264 mouse macrophages by suppressing ROS-mediated activation of PI3 K/Akt/NF-κB and p38 signaling pathways Biosci Biotechnol Biochem 2017 1956-1966 PubMed ID: 28812425

14379 Okabe I, Kikuchi T, Mogi M, Takeda H, Aino M, Kamiya Y, Fujimura T, Goto H, Okada K, Hasegawa Y, Noguchi T, Mitani A. IL-15 and RANKL Play a Synergistically Important Role in Osteoclastogenesis J Cell Biochem 2017 118(4):739-747 PubMed ID: 27608420

14456 Yokota S, Chosa N, Kyakumoto S, Kimura H, Ibi M, Kamo M, Satoh K, Ishisaki A. ROCK/actin/MRTF signaling promotes the fibrogenic phenotype of fibroblast-like synoviocytes derived from the temporomandibular joint Int J Mol Med 2017 39(4):799-808 PubMed ID: 28259960

14479 Nishina A, Shimizu K, Koketsu M, Ninomiya M, Sato D, Suzuki T, Hayakawa S, Kimura H. 5,7-Dihydroxyflavone Analogues May Regulate Lipopolysaccharide-Induced Inflammatory Responses by Suppressing I κ B α-Linked Akt and ERK5 Phosphorylation in RAW 264.7 Macrophages Evid Based Complement Alternat Med 2017 7898973 PubMed ID: 28539967

14480 Li G, Miura K, Kuno M. Extracellular phosphates enhance activities of voltage-gated proton channels and production of reactive oxygen species in murine osteoclast-like cells Pflugers Arch 2017 469(2):279-292 PubMed ID: 27999941

14565 Igeta K, Kuwamura Y, Horiuchi N, Nozaki K, Shiraishi D, Aizawa M, Hashimoto K, Yamashita K, Nagai A. Morphological and functional changes in RAW264 macrophage-like cells in response to a hydrated layer of carbonate-substituted hydroxyapatite J Biomed Mater Res A 2017 105(4):1063-1070 PubMed ID: 28085214

14570 Differential Regulation of IL-1β and IL-6 Release in Murine Macrophages Differential Regulation of IL-1β and IL-6 Release in Murine Macrophages Inflammation 2017 40(6):1933-1943 PubMed ID: 28766178

14571 Takakuwa S, Mizuno N, Takano T, Asakawa S, Sato T, Hiratsuka M, Hirasawa N. Down-regulation of Na +/H + exchanger 1 by Toll-like receptor stimulation in macrophages Immunobiology 2017 222(2):176-182 PubMed ID: 27771174

14572 Kanaoka Y, Koga M, Sugiyama K, Ohishi K, Kataoka Y, Yamauchi A. Varenicline enhances oxidized LDL uptake by increasing expression of LOX-1 and CD36 scavenger receptors through α 7 nAChR in macrophages Toxicology 2017 380:62-7 PubMed ID: 28202387

14656 Tanaka KI, Sugizaki T, Kanda Y, Tamura F, Niino T, Kawahara M Preventive Effects of Carnosine on Lipopolysaccharide-induced Lung Injury Sci Rep 2017 7:42813 PubMed ID: 28205623

14714 Ikeda Y, Kawai K, Ikawa A, Kawamoto K, Egami Y, Araki N. Rac1 switching at the right time and location is essential for Fcγ receptor-mediated phagosome formation J Cell Sci 2017 130(15):2530-2540 PubMed ID: 28600322

14725 Minegishi S, Yumura A, Miyoshi H, Negi S, Taketani S, Motterlini R, Foresti R, Kano K, Kitagishi H. Detection and Removal of Endogenous Carbon Monoxide by Selective and Cell-Permeable Hemoprotein Model Complexes J Am Chem Soc 2017 139(16):5984-5991 PubMed ID: 28388069

14773 Yokota H, Tsuzuki A, Shimada Y, Imai A, Utsumi D, Tsukahara T, Matsumoto M, Amagase K, Iwata K, Nakamura A, Yabe-Nishimura C, Kato S. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid-Induced Murine Colitis J Pharmacol Exp Ther 2017 360(1):192-200 PubMed ID: 27754929

15301 Hayashi K, Sato Y, Maruoka H, Sakamoto W, Yogo T. Organic-Inorganic Hybrid Nanoparticles for Tracking the Same Cells Seamlessly at the Cellular, Tissue, and Whole Body Levels ACS Biomater Sci Eng 2017 3(6):1129-1135 PubMed ID: 33429587

7077 Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake K, Takatsu K. Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice. Sci Rep 2016 6:23097 PubMed ID: 26975571

7094 Ryohei Hamaguchi, Yukihiro Kuroda A Novel Biomarker for Cellular Toxicity and Phospholipid Accumulation by Cationic Amphiphilic Drugs. Chromatography 2016 37:35-38

7119 Taniguchi M, Ochiai A, Matsushima K, Tajima K, Kato T, Saitoh E, Tanaka T. Endotoxin-neutralizing activity and mechanism of action of a cationic α-helical antimicrobial octadecapeptide derived from α-amylase of rice. Peptides 2016 75:101-8 PubMed ID: 26643956

7148 Ohta T, Kusano K, Ido A, Miura C, Miura T. Silkrose: A novel acidic polysaccharide from the silkmoth that can stimulate the innate immune response. Carbohydr Polym 2016 136:995-1001 PubMed ID: 26572439

7157 Higuchi H, Shoji T, Murase Y, Iijima S, Nishijima K. Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264. Biosci. Biotechnol. Biochem. 2016 80:501-9 PubMed ID: 26540411

7230 Takayama S, Hashimoto K, Kokubu E, Taniguchi M, Tajima K, Ochiai A, Saitoh E, Saito A, Ishihara K, Kato T. Inhibitory effects of a novel cationic dodecapeptide [CL(14-25)] derived from cyanate lyase of rice on endotoxic activities of LPSs from Escherichia coli and periodontopathic Aggregatibacter actinomycetemcomitans. Microb. Pathog. 2016 94:2-11 PubMed ID: 26318142

7469 Hashimoto M, Sasaki J, Imazato S. Investigation of the cytotoxicity of aluminum oxide nanoparticles and nanowires and their localization in L929 fibroblasts and RAW264 macrophages. J. Biomed. Mater. Res. Part B Appl. Biomater. 2016 104:241-52 PubMed ID: 25715832

9520 Lu Y, Cao L, Egami Y, Kawai K, Araki N. Cofilin contributes to phagocytosis of IgG-opsonized particles but not non-opsonized particles in RAW264 macrophages. Microscopy (Oxf) 2016 65:233-42 PubMed ID: 26754560

9550 Takeuchi T, Nagasaka M, Shimizu M, Tamura M, Arata Y. N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation. Bone Rep 2016 5:15-21 PubMed ID: 28326343

9554 Kuno M, Li G, Moriura Y, Hino Y, Kawawaki J, Sakai H. Acid-inducible proton influx currents in the plasma membrane of murine osteoclast-like cells. Pflugers Arch. 2016 468:837-47 PubMed ID: 26843093

9564 Wada T, Sunaga H, Miyata K, Shirasaki H, Uchiyama Y, Shimba S. Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression. J. Biol. Chem. 2016 291:7004-16 PubMed ID: 26865635

9569 Pengjam Y, Madhyastha H, Madhyastha R, Yamaguchi Y, Nakajima Y, Maruyama M. NF-κB pathway inhibition by anthrocyclic glycoside aloin is key event in preventing osteoclastogenesis in RAW264.7 cells. Phytomedicine 2016 23:417-28 PubMed ID: 27002412

9573 Maeda Y, Echizen K, Oshima H, Yu L, Sakulsak N, Hirose O, Yamada Y, Taniguchi T, Jenkins BJ, Saya H, Oshima M. Myeloid Differentiation Factor 88 Signaling in Bone Marrow-Derived Cells Promotes Gastric Tumorigenesis by Generation of Inflammatory Microenvironment. Cancer Prev Res (Phila) 2016 9:253-63 PubMed ID: 26888865

9607 Sugiyama K, Muroi M, Kinoshita M, Hamada O, Minai Y, Sugita-Konishi Y, Kamata Y, Tanamoto K. NF-κB activation via MyD88-dependent Toll-like receptor signaling is inhibited by trichothecene mycotoxin deoxynivalenol. J Toxicol Sci 2016 41:273-9 PubMed ID: 26961612

9609 Nakabayashi H, Aoyama S, Kawahara M, Nagamune T. Differentiation signalobody: Demonstration of antigen-dependent osteoclast differentiation from a progenitor cell line. J. Biosci. Bioeng. 2016 122:357-63 PubMed ID: 26979343

9612 Furuoka M, Ozaki K, Sadatomi D, Mamiya S, Yonezawa T, Tanimura S, Takeda K. TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells. J. Cell. Physiol. 2016 231:2761-7 PubMed ID: 26989816

9673 Okahashi N, Nakata M, Kuwata H, Kawabata S. Streptococcus oralis Induces Lysosomal Impairment of Macrophages via Bacterial Hydrogen Peroxide. Infect. Immun. 2016 84:2042-2050 PubMed ID: 27113357

9690 Elfeky M, Kaede R, Okamatsu-Ogura Y, Kimura K. Adiponectin Inhibits LPS-Induced HMGB1 Release through an AMP Kinase and Heme Oxygenase-1-Dependent Pathway in RAW 264 Macrophage Cells. Mediators Inflamm. 2016 2016:5701959 PubMed ID: 27313399

9692 Kure A, Nakagawa K, Kondo M, Kato S, Kimura F, Watanabe A, Shoji N, Hatanaka S, Tsushida T, Miyazawa T. Metabolic Fate of Luteolin in Rats: Its Relationship to Anti-inflammatory Effect. J. Agric. Food Chem. 2016 64:4246-54 PubMed ID: 27170112

9706 Zhang J, Hiromoto S, Yamazaki T, Niu J, Huang H, Jia G, Li H, Ding W, Yuan G. Effect of macrophages on in vitro corrosion behavior of magnesium alloy. J Biomed Mater Res A 2016 104:2476-87 PubMed ID: 27223576

9740 Sunarso , Toita R, Tsuru K, Ishikawa K. A superhydrophilic titanium implant functionalized by ozone gas modulates bone marrow cell and macrophage responses. J Mater Sci Mater Med 2016 27:127 PubMed ID: 27344451

9747 Arikawa M, Kakinuma Y, Noguchi T, Todaka H, Sato T. Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation. Eur. J. Pharmacol. 2016 789:17-26 PubMed ID: 27373848

9818 Kanzaki H, Shinohara F, Suzuki M, Wada S, Miyamoto Y, Yamaguchi Y, Katsumata Y, Makihira S, Kawai T, Taubman MA, Nakamura Y. A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma. Sci Rep 2016 6:32259 PubMed ID: 27573075

9882 Moriwaki S, Into T, Suzuki K, Miyauchi M, Takata T, Shibayama K, Niida S. γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis. Sci Rep 2016 6:35930 PubMed ID: 27775020

9922 Yamawaki T, Ito E, Mukai A, Ueno M, Yamada J, Sotozono C, Kinoshita S, Hamuro J. The Ingenious Interactions Between Macrophages and Functionally Plastic Retinal Pigment Epithelium Cells. Invest. Ophthalmol. Vis. Sci. 2016 57:5945-5953 PubMed ID: 27820950

9969 Domon H, Oda M, Maekawa T, Nagai K, Takeda W, Terao Y. Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis. Sci Rep 2016 6:38013 PubMed ID: 27892542

10852 Kejuan Li, Xi Yang, Xuansheng Hu, Chao Han, Zhongfang Lei, Zhenya Zhang In vitro antioxidant, immunomodulatory and anticancer activities of two fractions of aqueous extract from Helicteres angustifolia L. root Journal of the Taiwan Institute of Chemical Engineers 2016 61:75-82

10857 Clinical Evaluation of Novel Natural Polysaccharides Sacran as a Skincare Material for Atopic Dermatitis Patients Journal of Cosmetics, Dermatological Sciences and Applications 2016 6, 9-18

10869 Isolation and Biochemical Characterization of Mucus Proteins in Japanese Bunching Onion (Allium fistulosum) Green Leaves Food Science and Technology Research 2016 22

9409 Nobutaka Sato 1, Jiro Ichikawa 1, Masanori Wako, Tetsuro Ohba, Masanori Saito, Hironao Sato, Kensuke Koyama, Tetsuo Hagino, Jonathan G Schoenecker, Takashi Ando, Hirotaka Haro Thrombin Induced by the Extrinsic Pathway and PAR-1 Regulated Inflammation at the Site of Fracture Repair Bone 2016 83:23-34 PubMed ID: 26475502

10109 Yusuke Kono, Ayu Iwasaki, Kenta Matsuoka, Takuya Fujita Effect of Mechanical Agitation on Cationic Liposome Transport Across an Unstirred Water Layer in Caco-2 Cells Biol Pharm Bull 2016 39(8):1293-9 PubMed ID: 27476939

12622 Goto T, Naknukool S, Yoshitake R, Hanafusa Y, Tokiwa S, Li Y, Sakamoto T, Nitta T, Kim M, Takahashi N, Yu R, Daiyasu H, Seno S, Matsuda H, Kawada T. Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes Cytokinec 2016 77:107-14 PubMed ID: 26556104

12858 Hashimoto M, Kawai K, Kawakami H, Imazato S. Matrix metalloproteases inhibition and biocompatibility of gold and platinum nanoparticles J Biomed Mater Res A 2016 104(1):209-17. PubMed ID: 26282184

12885 Ichikawa N, Yamashita K, Funakoshi T, Ichihara S, Fukai M, Ogura M, Kobayashi N, Zaitsu M, Yoshida T, Shibasaki S, Koshizuka Y, Tsunetoshi Y, Sato M, Einama T, Ozaki M, Umezawa K, Suzuki T, Todo S. Novel anti-inflammatory agent 3-[(dodecylthiocarbonyl)-methyl]-glutarimide ameliorates murine models of inflammatory bowel disease Inflamm Res 2016 65(3):245-60 PubMed ID: 26683259

12936 Hayashida Y, Ikeda Y, Sawada K, Kawai K, Kato T, Kakehi Y, Araki N. Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor Int J Cancer 2016 139(3):700-11 PubMed ID: 26989815

12956 Nagahara H, Yamamoto A, Seno T, Obayashi H, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y. Allograft inflammatory factor-1 in the pathogenesis of bleomycin-induced acute lung injury Biosci Trends 2016 10(1):47-53. PubMed ID: 26911661

13985 Nakayama M, Nakamura A, Hondou T, Miyata H. Evaluation of cell viability, DNA single-strand breaks, and nitric oxide production in LPS-stimulated macrophage RAW264 exposed to a 50-Hz magnetic field Int J Radiat Biol 2016 ;92(10):583-9 PubMed ID: 27430265

14099 Yamamoto S, Ohta N, Matsumoto A, Horiguchi Y, Koide M, Fujino Y. Haloperidol Suppresses NF-kappaB to Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Response in RAW 264 Cells Med Sci Monit 2016 22:367-72 PubMed ID: 26842661

14110 Taki M, Tagami T, Fukushige K, Ozeki T. Fabrication of nanocomposite particles using a two-solution mixing-type spray nozzle for use in an inhaled curcumin formulation Int J Pharm 2016 511(1):104-110 PubMed ID: 27374204

14164 Yiting Li, Shili Meng, Min Shi, Xuansheng Hu, Yingnan Yang, Zhenya Zhang Bioactivity Evaluation of Crude Polysaccharide from Rice Bran Fermented by Preussia Aemulans and the Changes in its Nutritional Contents Journal of Food Biochemistry 2016 40:664-672

14578 Ito S, Tanaka Y, Oshino R, Okado S, Hori M, Isobe KI. GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation Cell Death Dis 2016 7(5):e2219 PubMed ID: 27171261

15302 Yuichi Masuda, Chitose Maruyama, Kyuichi Kawabata, Yoshimitsu Hamano, Takayuki Doi Synthesis of (2S,3R,4R)-3,4-dihydroxyarginine and its inhibitory activity against nitric oxide synthase Tetrahedron 2016 72:5602-5611

7085 Hosokawa T, Tsuchiya Y, Okubo N, Kunimoto T, Minami Y, Fujiwara H, Umemura Y, Koike N, Kubo T, Yagita K. Robust Circadian Rhythm and Parathyroid Hormone-Induced Resetting during Hypertrophic Differentiation in ATDC5 Chondroprogenitor Cells. Acta Histochem Cytochem 2015 48:165-71 PubMed ID: 26855448

7137 Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa TO, Kataoka Y, Yamamura K. Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo. Sci Rep 2015 5:17205 PubMed ID: 26598133

7142 Washio K, Kobayashi M, Saito N, Amagasa M, Kitamura H. Propolis Ethanol Extract Stimulates Cytokine and Chemokine Production through NF-κB Activation in C2C12 Myoblasts. Evid Based Complement Alternat Med 2015 2015:349751 PubMed ID: 26604971

7221 Sawada Y, Sakamoto Y, Toh M, Ohara N, Hatanaka Y, Naka A, Kishimoto Y, Kondo K, Iida K. Milk-derived peptide Val-Pro-Pro (VPP) inhibits obesity-induced adipose inflammation via an angiotensin-converting enzyme (ACE) dependent cascade. Mol Nutr Food Res 2015 59:2502-10 PubMed ID: 26346532

7229 Inoue K, Imai Y. Fatostatin, an SREBP inhibitor, prevented RANKL-induced bone loss by suppression of osteoclast differentiation. Biochim. Biophys. Acta 2015 1852:2432-41 PubMed ID: 26319416

7274 Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K. IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis. J. Clin. Invest. 2015 125:3269-79 PubMed ID: 26193638

7293 Tang L, Okamoto S, Shiuchi T, Toda C, Takagi K, Sato T, Saito K, Yokota S, Minokoshi Y. Sympathetic Nerve Activity Maintains an Anti-Inflammatory State in Adipose Tissue in Male Mice by Inhibiting TNF-α Gene Expression in Macrophages. Endocrinology 2015 156:3680-94 PubMed ID: 26132918

7321 Hashimoto M, Sasaki JI, Yamaguchi S, Kawai K, Kawakami H, Iwasaki Y, Imazato S. Gold Nanoparticles Inhibit Matrix Metalloproteases without Cytotoxicity. J. Dent. Res. 2015 94:1085-91 PubMed ID: 26040283

7340 Suzuki N, Takimoto K, Kawashima N. Cathepsin K Inhibitor Regulates Inflammation and Bone Destruction in Experimentally Induced Rat Periapical Lesions. J Endod 2015 41:1474-9 PubMed ID: 25990199

7420 Miyazaki T, Miyauchi S, Anada T, Tawada A, Suzuki O. Chondroitin Sulfate-E Binds to Both Osteoactivin and Integrin αVβ3 and Inhibits Osteoclast Differentiation. J. Cell. Biochem. 2015 116:2247-57 PubMed ID: 25820496

7448 Takeuchi T, Shimakawa G, Tamura M, Yokosawa H, Arata Y. ISG15 regulates RANKL-induced osteoclastogenic differentiation of RAW264 cells. Biol. Pharm. Bull. 2015 38:482-6 PubMed ID: 25757932

7451 Hashimoto M, Imazato S. Cytotoxic and genotoxic characterization of aluminum and silicon oxide nanoparticles in macrophages. Dent Mater 2015 31:556-64 PubMed ID: 25749564

7467 Kawabata K, Kato Y, Sakano T, Baba N, Hagiwara K, Tamura A, Baba S, Natsume M, Ohigashi H. Effects of phytochemicals on in vitro anti-inflammatory activity of Bifidobacterium adolescentis. Biosci. Biotechnol. Biochem. 2015 79:799-807 PubMed ID: 25721815

7492 Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M. Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury. Am. J. Physiol. Renal Physiol. 2015 308:F878-87 PubMed ID: 25656369

7501 Lai YT, Sato M, Ohta S, Akamatsu K, Nakao S, Sakai Y, Ito T. Preparation of uniform-sized hemoglobin-albumin microspheres as oxygen carriers by Shirasu porous glass membrane emulsification technique. Colloids Surf B Biointerfaces 2015 127:1-7 PubMed ID: 25635614

7505 Kim YI, Mohri S, Hirai S, Lin S, Goto T, Ohyane C, Sakamoto T, Takahashi H, Shibata D, Takahashi N, Kawada T. Tomato extract suppresses the production of proinflammatory mediators induced by interaction between adipocytes and macrophages. Biosci. Biotechnol. Biochem. 2015 79:82-7 PubMed ID: 25603813

7517 Taniguchi M, Ochiai A, Takahashi K, Nakamichi S, Nomoto T, Saitoh E, Kato T, Tanaka T. Antimicrobial activity and mechanism of action of a novel cationic α-helical octadecapeptide derived from α-amylase of rice. Biopolymers 2015 104:73-83 PubMed ID: 25581614

7526 F Shima, T Akagi, M Shudo, E Mochizuki, T Tsuda, S Kuwabata M Akashi Interaction between living cells and polymeric particles: potential application of ionic liquid for evaluating the cellular uptake of biodegradable polymeric particles composed of poly(amino acid). Polymer Journal 2015 47:631-638

6343 Uto T, Tung NH, Taniyama R, Miyanowaki T, Morinaga O, Shoyama Y. Anti-inflammatory Activity of Constituents Isolated from Aerial Part of Angelica acutiloba Kitagawa. Phytother Res 2015 29(12):1956-63 PubMed ID: 26463105

6621 Koyama T, Kamemura K. Global increase in O-linked N-acetylglucosamine modification promotes osteoblast differentiation. Exp Cell Res 2015 338(2):194-202 PubMed ID: 26302267

9365 Akio Watanabe, Momochika Kumagai, Takashi Mishima, Junya Ito, Yurika Otoki, Teppei Harada, Tsuyoshi Kato, Mikihiko Yoshida, Misora Suzuki, Izumi Yoshida, Kazuhiro Fujita, Masatoshi Watai, Kiyotaka Nakagawa, Teruo Miyazawa Toddaculin, Isolated From of Toddalia Asiatica (L.) Lam., Inhibited Osteoclastogenesis in RAW 264 Cells and Enhanced Osteoblastogenesis in MC3T3-E1 Cells PLoS One 2015 10(5):e0127158 PubMed ID: 25993011

9378 R Toita, Sunarso, A N Rashid, K Tsuru, K Ishikawa Modulation of the Osteoconductive Property and Immune Response of Poly(ether Ether Ketone) by Modification With Calcium Ions J Mater Chem B 2015 3(44):8738-8746 PubMed ID: 32262731

10173 Yao-Tong Lai, Seiichi Ohta, Kazuki Akamatsu, Shin-Ichi Nakao, Yasuyuki Sakai, Taichi Ito Size-dependent Interaction of Cells and Hemoglobin-Albumin Based Oxygen Carriers Prepared Using the SPG Membrane Emulsification Technique Biotechnol Prog . 2015 31(6):1676-84 PubMed ID: 26399378

10195 Akihiko Nagao, Takashi Maoka, Hiroshi Ono, Eiichi Kotake-Nara, Miyuki Kobayashi, Mie Tomita A 3-hydroxy β-End Group in Xanthophylls Is Preferentially Oxidized to a 3-oxo ε-End Group in Mammals J Lipid Res 2015 56(2):449-62 PubMed ID: 25502844

12234 Masayori Hagimori, Naoko Mizuyama, Yoshinori Tominaga, Takahiro Mukai,Hideo Saji A low-molecular-weight fluorescent sensor with Zn2+ dependent bathochromic shift of emission wavelength and its imaging in living cells Dyes and Pigments 2015 113:205-209

12237 Shiro Kato, Yuki Masuda, Morichika Konishi, Tadao Oikawa Enantioselective analysis of D- and L-amino acids from mouse macrophages using high performance liquid chromatography J Pharm Biomed Anal 2015 116:101-4 PubMed ID: 25982753

12245 Takashi Ando, Takayuki Komatsu, Yoshikazu Naiki, Takashi Yokochi, Daisuke Watanabe, Naoki Koide Pretreatment of LPS inhibits IFN-β-induced STAT1 phosphorylation through SOCS3 induced by LPS Biomed Pharmacother 2015 76:1-5 PubMed ID: 26653542

12252 Yoshiro Kato, Hideki Kamiya, Naoki Koide, Erdenezaya Odkhuu, Takayuki Komatsu, Atsuko Watarai, Masaki Kondo, Koichi Kato, Jiro Nakamura, Takashi Yokochi Irbesartan attenuates production of high-mobility group box 1 in response to lipopolysaccharide via downregulation of interferon-β production Int Immunopharmacol 2015 26(1):97-102 PubMed ID: 25817178

12259 Shusong Wu, Xi He, Xiaosong Wu, Si Qin, Jianhua He, Shirui Zhang, De-Xing Hou Inhibitory effects of blue honeysuckle (Lonicera caerulea L) on adjuvant-induced arthritis in rats: Crosstalk of anti-inflammatory and antioxidant effects J Functional Foods 2015 17:514-515

13961 Fujioka K, Kishida T, Ejima A, Yamamoto K, Fujii W, Murakami K, Seno T, Yamamoto A, Kohno M, Oda R, Yamamoto T, Fujiwara H, Kawahito Y, Mazda O. Inhibition of osteoclastogenesis by osteoblast-like cells genetically engineered to produce interleukin-10 Biochem Biophys Res Commun 2015 456(3):785-91 PubMed ID: 25514036

14465 Okinaga T, Ariyoshi W, Nishihara T. Aggregatibacter actinomycetemcomitans Invasion Induces Interleukin-1β Production Through Reactive Oxygen Species and Cathepsin B J Interferon Cytokine Res 2015 35(6):431-40 PubMed ID: 25789553

14969 Kiyomiya H, Ariyoshi W, Okinaga T, Kaneuji T, Mitsugi S, Sakurai T, Habu M, Yoshioka I, Tominaga K, Nishihara T. IL-33 inhibits RANKL-induced osteoclast formation through the regulation of Blimp-1 and IRF-8 expression Biochem Biophys Res Commun 2015 460(2):320-6 PubMed ID: 25795135

14983 He YM, Zhu S, Ge YW, Kazuma K, Zou K, Cai SQ, Komatsu K. The anti-inflammatory secoiridoid glycosides from gentianae scabrae radix: the root and rhizome of Gentiana scabra J Nat Med 2015 69(3):303-12 PubMed ID: 25750086

14991 Komiya M, Fujii G, Miyamoto S, Takahashi M, Ishigamori R, Onuma W, Ishino K, Totsuka Y, Fujimoto K, Mutoh M. Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK-A(y) and Apc mutant Min mice Cancer Sci 2015 106(11):1499-505 PubMed ID: 26310859

15020 Mori K, Ouchi K, Hirasawa N. The Anti-Inflammatory Effects of Lion's Mane Culinary-Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) in a Coculture System of 3T3-L1 Adipocytes and RAW264 Macrophages Int J Med Mushrooms 2015 17(7):609-18 PubMed ID: 26559695

15021 Tan H, Ashour A, Katakura Y, Shimizu K. A structure-activity relationship study on antiosteoclastogenesis effect of triterpenoids from the leaves of loquat (Eriobotrya japonica) Phytomedicine 2015 22(4):498-503 PubMed ID: 25925972

15028 Inaba H, Yoshigai E, Okuyama T, Murakoshi M, Sugiyama K, Nishino H, Nishizawa M. Antipyretic analgesic drugs have different mechanisms for regulation of the expression of inducible nitric oxide synthase in hepatocytes and macrophages Nitric Oxide 2015 44:61-70 PubMed ID: 25499030

15148 Kojima C, Kameyama R, Yamada M, Ichikawa M, Waku T, Handa A, Tanaka N. Ovalbumin Delivery by Guanidine-Terminated Dendrimers Bearing an Amyloid-Promoting Peptide via Nanoparticle Formulation Bioconjug Chem 2015 26(8):1804-10 PubMed ID: 26186179

13891 Nakamura R, Kayamori K, Oue E, Sakamoto K, Harada K, Yamaguchi A. Transforming growth factor-β synthesized by stromal cells and cancer cells participates in bone resorption induced by oral squamous cell carcinoma Biochem Biophys Res Commun 2015 458(4):777-82 PubMed ID: 25681764

15208 Wang Q, Yokoo H, Takashina M, Sakata K, Ohashi W, Abedelzaher LA, Imaizumi T, Sakamoto T, Hattori K, Matsuda N, Hattori Y. Anti-Inflammatory Profile of Levosimendan in Cecal Ligation-Induced Septic Mice and in Lipopolysaccharide-Stimulated Macrophages Crit Care Med 2015 43(11):e508-20 PubMed ID: 26468714

15255 Asakawa S, Kishimoto Y, Takano T, Okita K, Takakuwa S, Sato T, Hiratsuka M, Takeuchi O, Hirasawa N. Nickel ions selectively inhibit lipopolysaccharide-induced interleukin-6 production by decreasing its mRNA stability PLoS One 2015 10(3):e0119428 PubMed ID: 25742007

15444 Oka H, Kitagawa M, Takata T. F-spondin inhibits differentiation of clastic precursors via lipoprotein receptor-related protein 8 (LRP8) J Periodontol 2015 86(3):465-72 PubMed ID: 25299387

15446 Nomura H, Takanashi S, Tanaka M, Haniu H, Aoki K, Okamoto M, Kobayashi S, Takizawa T, Usui Y, Oishi A, Kato H, Saito N. Specific biological responses of the synovial membrane to carbon nanotubes Sci Rep 2015 5:14314 PubMed ID: 26388047

15305 Oh-Hashi K, Sone A, Hikiji T, Hirata Y, Vitiello M, Fedele M, Ishigaki S, Sobue G, Kiuchi K. Transcriptional and post-transcriptional regulation of transmembrane protein 132A Mol Cell Biochem 2015 405(1-2):291-9 PubMed ID: 25926156

15479 Ito S, Tanaka Y, Oshino R, Aiba K, Thanasegaran S, Nishio N, Isobe K. GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy Sci Rep 2015 5:8327 PubMed ID: 25659802

15103 Cuilian Tao, Yufang Zhu, Xianglan Li, Nobutaka Hanagata Binding of CpG oligodeoxynucleotides to mesoporous silica nanoparticles for enhancing delivery efficiency Microporous and Mesoporous Materials 2015 204:91-98

6334 Itoh T, Tsuchida A, Muramatsu Y, Ninomiya M, Ando M, Tsukamasa Y, Koketsu M. Antimicrobial and anti-inflammatory properties of nostocionone isolated from Nostoc commune Vauch and its derivatives against Propionibacterium acnes. Anaerobe 2014 27:56-63 PubMed ID: 24699048

2777 Yamasaki T, Ariyoshi W, Okinaga T, Adachi Y, Hosokawa R, Mochizuki S, Sakurai K, Nishihara T. The dectin 1 agonist curdlan regulates osteoclastogenesis by inhibiting nuclear factor of activated T cells cytoplasmic 1 (NFATc1) through Syk kinase. J Biol Chem 2014 289(27):19191-203 PubMed ID: 24821724

6607 Nakazato R, Takarada T, Watanabe T, Nguyen BT, Ikeno S, Hinoi E, Yoneda Y. Constitutive and functional expression of runt-related transcription factor-2 by microglial cells. Neurochem Int 2014 74:24-35 PubMed ID: 24768841

9114 Erdenezaya Odkhuu, Takayuki Komatsu, Yoshikazu Naiki, Naoki Koide, Takashi Yokochi Sendai Virus C Protein Inhibits Lipopolysaccharide-Induced Nitric Oxide Production Through Impairing Interferon-β Signaling Int Immunopharmacol 2014 23 (1), 267-72 PubMed ID: 25242386

9323 Ran Zhao, Masayoshi Kamon, Kazuichi Sakamoto (–)-Epigallocatechingallate Interferes RANKL/RANK Signal Pathway and Induces Apoptosis during Osteoclastogenesis in RAW264 Cell Food and Nutrition Sciences 2014 5:107-116

9348 W Ariyoshi, T Okinaga, C B Knudson, W Knudson, T Nishihara High Molecular Weight Hyaluronic Acid Regulates Osteoclast Formation by Inhibiting Receptor Activator of NF-κB Ligand Through Rho Kinase Osteoarthritis Cartilage 2014 22(1):111-20 PubMed ID: 24185105

9349 Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo Responses of RAW264.7 Macrophages to Water-Dispersible Gold and Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds J Biomed Mater Res A 2014 102(6):1838-49 PubMed ID: 23784947

9351 Miki Tadaishi, Yoriko Nishide, Yuko Tousen, Marlena C Kruger, Yoshiko Ishimi Cooperative Effects of Soy Isoflavones and Carotenoids on Osteoclast Formation J Clin Biochem Nutr 2014 54(2):109-15 PubMed ID: 24688220

12850 Tada R, Koide Y, Yamamuro M, Tanaka R, Hidaka A, Nagao K, Aramaki Y. Maleylated-BSA suppresses lipopolysaccharide-induced IL-6 production by activating the ERK-signaling pathway in murine RAW264.7 cells Int Immunopharmacol 2014 19(1):5-9 PubMed ID: 24406428

15027 Dan Zhu, Hongyi Sun, Shuhong Li, Xuansheng Hu, Xi Yuan, Chao Han, Zhenya Zhang Influence of Drying Methods on Antioxidant Activities and Immunomodulatory of Aqueous Extract From Soybean Curd Residue Fermentated by Grifola frondosa International Journal of Biology 2014 7:82-92

15306 Itoh T, Koketsu M, Yokota N, Touho S, Ando M, Tsukamasa Y. Reduced scytonemin isolated from Nostoc commune suppresses LPS/IFNγ-induced NO production in murine macrophage RAW264 cells by inducing hemeoxygenase-1 expression via the Nrf2/ARE pathway Food Chem Toxicol 2014 ;69:330-8 PubMed ID: 24795232

15307 Daisuke Yamanaka, Katsuya Tajima, Yoshiyuki Adachi, Ken-ichi Ishibashi, Noriko N. Miura, Masuro Motoi, Naohito Ohno Effect of polymeric caffeic acid on antitumour activity and natural killer cell activity in mice Journal of Functional Foods 2014 6:513-522

15308 Hayashi Y, Kuroda T, Kishimoto H, Wang C, Iwama A, Kimura K. Downregulation of rRNA transcription triggers cell differentiation PLoS One 2014 9(5):e98586 PubMed ID: 24879416

15309 Kusunoki H, Taniyama Y, Otsu R, Rakugi H, Morishita R. Anti-inflammatory effects of hepatocyte growth factor on the vicious cycle of macrophages and adipocytes Hypertens Res 2014 37(6):500-6 PubMed ID: 24621470

15310 Sato S, Sakurai T, Ogasawara J, Shirato K, Ishibashi Y, Oh-ishi S, Imaizumi K, Haga S, Hitomi Y, Izawa T, Ohira Y, Ohno H, Kizaki T. Direct and indirect suppression of interleukin-6 gene expression in murine macrophages by nuclear orphan receptor REV-ERBα ScientificWorldJournal 2014 2014:685854 PubMed ID: 25401152

15311 Araki N, Ikeda Y, Kato T, Kawai K, Egami Y, Miyake K, Tsurumaki N, Yamaguchi M. Development of an automated fluorescence microscopy system for photomanipulation of genetically encoded photoactivatable proteins (optogenetics) in live cells Microscopy (Oxf) 2014 63(3):255-60 PubMed ID: 24523516

15312 Sato Y, Hara H, Okuno T, Ozaki N, Suzuki S, Yokomizo T, Kaisho T, Yoshida H. IL-27 affects helper T cell responses via regulation of PGE2 production by macrophages Biochem Biophys Res Commun 2014 451(2):215-21 PubMed ID: 25088998

15313 Seiji GODA, Hiroshi HAYASHI, Yosuke UJII, Osamu TAKEUCHI, Reiko KOMASA, Eisuke DOMAE, Kazuyo YAMAMOTO, Naoyuki MATSUMOTO, Takashi IKEO Fibronectin inhibited RANKL-induced differentiation into osteoclast Journal of Oral Tissue Engineering 2014 11:227-233

15314 Sarntivijai S, Lin Y, Xiang Z, Meehan TF, Diehl AD, Vempati UD, Schürer SC, Pang C, Malone J, Parkinson H, Liu Y, Takatsuki T, Saijo K, Masuya H, Nakamura Y, Brush MH, Haendel MA, Zheng J, Stoeckert CJ, Peters B, Mungall CJ, Carey TE, States DJ, Athey BD, He Y. CLO: The cell line ontology J Biomed Semantics 2014 5:37 PubMed ID: 25852852

15315 Suk Hyun Choi, Dong-Seok Kim, Nobuyuki Kozukue, Hyun-Jeong Kim, Yosuke Nishitani, Masashi Mizuno, Carol E. Levin, Mendel Friedman Protein, free amino acid, phenolic, β-carotene, and lycopene content, and antioxidative and cancer cell inhibitory effects of 12 greenhouse-grown commercial cherry tomato varieties Journal of Food Composition and Analysis 2014 34:115-127

15316 Xu Y, Ito T, Fushimi S, Takahashi S, Itakura J, Kimura R, Sato M, Mino M, Yoshimura A, Matsukawa A. Spred-2 deficiency exacerbates lipopolysaccharide-induced acute lung inflammation in mice PLoS One 2014 9(9):e108914 PubMed ID: 25275324

15317 Uehara K, Takahashi A, Watanabe M, Nomura Y. Shark protein improves bone mineral density in ovariectomized rats and inhibits osteoclast differentiation Nutrition 2014 30(6):719-25 PubMed ID: 24800672

15319 Ueno-Shuto K, Kato K, Tasaki Y, Sato M, Sato K, Uchida Y, Sakai H, Ono T, Suico MA, Mitsutake K, Tokutomi N, Kai H, Shuto T. Lipopolysaccharide decreases single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR) expression by suppressing specificity protein 1 (Sp1) via the Toll-like receptor 4 (TLR4)-p38 pathway in monocytes and neutrophils J Biol Chem 2014 289(26):18097-109 PubMed ID: 24821721

15320 Phyu Phyu Khine Zar, Akiko Morishita, Fumio Hashimoto, Kozue Sakao, Makoto Fujii, Koji Wada, De-Xing Hou Anti-inflammatory effects and molecular mechanisms of loquat (Eriobotrya japonica) tea Journal of Functional Foods 2014 6:523-533

15322 Inoue M, Tanabe H, Nakashima K, Ishida Y, Kotani H. Rexinoids isolated from Sophora tonkinensis with a gene expression profile distinct from the synthetic rexinoid bexarotene J Nat Prod 2014 77(7):1670-7 PubMed ID: 24959987

15323 Kato Y, Kamiya H, Koide N, Odkhuu E, Komatsu T, Dagvadorj J, Watarai A, Kondo M, Kato K, Nakamura J, Yokochi T. Spironolactone inhibits production of proinflammatory mediators in response to lipopolysaccharide via inactivation of nuclear factor-κB Immunopharmacol Immunotoxicol 2014 36(3):237-41 PubMed ID: 24852317

7584 T. Atsumi, A. Iwashita, I. Ohtsuka, N. Kakiuchi, Y. Sasaki, M. Mikage, K. Toriizuka Effects of Atractylodis Lanceae Rhizoma on inflammatory mediator production from the RAW264 macrophage cell line J Traditional Medicines 2013 30:124-131

5424 Takeshi KAWAHARA, Daichi NAKAYAMA, Keisuke TODA, Shyuichiro INAGAKI, Katsumi TANAKA, Hisako YASUI Suppressive Effect of Wild Saccharomyces cerevisiae and Saccharomyces paradoxus Strains on Ige Production by Mouse Spleen Cells Food Sci. Technol. Res 2013 19 (6), 1019 – 1027

6086 Ito S, Tanaka Y, Nishio N, Thanasegaran S, Isobe K. Establishment of self-renewable GM-CSF-dependent immature macrophages in vitro from murine bone marrow. PLoS One 2013 8(10):e76943 PubMed ID: 24124601

6326 Horibe K, Nakamichi Y, Uehara S, Nakamura M, Koide M, Kobayashi Y, Takahashi N, Udagawa N. Roles of cathelicidin-related antimicrobial peptide in murine osteoclastogenesis. Immunology 2013 140(3):344-51 PubMed ID: 23826736

6466 Etoh T, Kim YP, Ohsaki A, Komiyama K, Hayashi M. Inhibitory effect of erythraline on Toll-like receptor signaling pathway in RAW264.7 cells. Biol Pharm Bull 2013 36(8):1363-9 PubMed ID: 23902980

6467 Etoh T, Kim YP, Tanaka H, Hayashi M. Anti-inflammatory effect of berkeleyacetal C through the inhibition of interleukin-1 receptor-associated kinase-4 activity. Eur J Pharmacol 2013 698(1-3):435-43 PubMed ID: 23127497

9096 Kyoko Ueda, Ryoko Kawabata, Takashi Irie, Yoshiaki Nakai, Yukinobu Tohya, Takemasa Sakaguchi Inactivation of Pathogenic Viruses by Plant-Derived Tannins: Strong Effects of Extracts From Persimmon (Diospyros Kaki) on a Broad Range of Viruses PLoS One 2013 8 (1), e55343 PubMed ID: 23372851

9100 Hiroki Ishikawa, Naoki Awano, Toshie Fukui, Hiraku Sasaki, Shigeru Kyuwa The Protective Effects of Lactoferrin Against Murine Norovirus Infection Through Inhibition of Both Viral Attachment and Replication Biochem Biophys Res Commun 2013 434 (4), 791-6 PubMed ID: 23603257

9169 Akari Ishisaka, Kyuichi Kawabata, Satomi Miki, Yuko Shiba, Shoko Minekawa, Tomomi Nishikawa, Rie Mukai, Junji Terao, Yoshichika Kawai Mitochondrial Dysfunction Leads to Deconjugation of Quercetin Glucuronides in Inflammatory Macrophages PLoS One 2013 8 (11), e80843 PubMed ID: 24260490

9256 Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Takashi Narushima, Masayuki Kaga, Kazuhiko Endo Micromorphological Cellular Responses of MC3T3-E1 and RAW264.7 After Exposure to Water-Dispersible Silver Nanoparticles Stabilized by Metal-Carbon σ-Bonds Dent Mater J 2013 32(5):725-33 PubMed ID: 24088827

9359 Yuriko Furuya, Atsushi Inagaki, Masud Khan, Kaoru Mori, Josef M Penninger, Midori Nakamura, Nobuyuki Udagawa, Kazuhiro Aoki, Keiichi Ohya, Kohji Uchida, Hisataka Yasuda Stimulation of Bone Formation in Cortical Bone of Mice Treated With a Receptor Activator of Nuclear factor-κB Ligand (RANKL)-binding Peptide That Possesses Osteoclastogenesis Inhibitory Activity J Biol Chem 2013 288(8):5562-71 PubMed ID: 23319583

9290 Hirohiko Okamura, Di Yang, Kaya Yoshida, Tatsuji Haneji Protein Phosphatase 2A Cα Is Involved in Osteoclastogenesis by Regulating RANKL and OPG Expression in Osteoblasts FEBS Lett 2013 587(1):48-53 PubMed ID: 23183242

12258 Kazuhiro Nakaya, Makoto Ayaori, Harumi Uto-Kondo, Grace Megumi Sotherden, Takafumi Nishida, Haruka Katamoto, Yuko Miura, Shunichi Takiguchi, Emi Yakushiji, Maki Iizuka, Masatsune Ogura, Makoto Sasaki, Makiko Yogo, Tomohiro Komatsu, Takeshi Adachi, Chizuko Maruyama, Katsunori Ikewaki Overexpression of stearoyl-coenzyme A desaturase 1 in macrophages promotes reverse cholesterol transport Biochim Biophys Acta 2013 1831(8):1402-11 PubMed ID: 23747827

4394 Suzuki S, Nishio SI, Ishii H, Sekido T, Takeshige K, Ohkubo Y, Hiwatashi D, Takeda T, Komatsu M. Possible roles of the AP-1 site in the cytosolic T3 binding protein promoter and insights into its physiological significance. Horm Metab Res 2013 45(7):501-6 PubMed ID: 23508717

13737 Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Masahiro Iijima, Kazuhiko Endo Masanori Hashimoto, Hirokazu Toshima, Tetsu Yonezawa, Koji Kawai, Masahiro Iijima, Kazuhiko Endo Journal of Biomaterials and Tissue Engineering 2013 4:51-58

14403 Tsolmongyn B, Koide N, Odkhuu E, Haque A, Naiki Y, Komatsu T, Yoshida T, Yokochi T. Lipopolysaccharide prevents valproic acid-induced apoptosis via activation of nuclear factor-κB and inhibition of p53 activation Cell Immunol 2013 282(2):100-5 PubMed ID: 23770718

15324 Rui Tada, Yusuke Koide, Mitsuaki Yamamuro, Akira Hidaka, Koichiro Nagao, Yoichi Negishi, Yukihiko Aramaki Maleylated-BSA induces TNF-α production through the ERK and NF-κB signaling pathways in murine RAW264.7 macrophages Open Journal of Immunology 2013 3:184-189

15325 Yuka Takasugi, Futoshi Kurai, Issei Kazume, Masaki Otsuka, Yoichi Negishi, Rui Tada, Yukihiko Aramaki Down Regulation of MyD88 in Macrophages Treated with Liposomes Composed of Phosphatidylserine Pharmacology & Pharmacy 2013 4:248-254

15326 Yuko Katao, Hirofumi Sawai, Mika Shishido, Aki Omae, Wen Liao, Kaoru Inami, Naoyuki Matsumoto Augmentation of RANKL-induced osteoclast differentiation by Z-VAD-fmk, a pan-caspase inhibitor Journal of Osaka Dental University 2013 47:41-46

15327 Fumiaki Shima, Koshi Kawakami, Takami Akagi, Eiko Mochizuki, Tetsuya Tsuda, Susumu Kuwabata, Mitsuru Akashi Simple Observation of the Interaction between Nanoparticles and Cells by Scanning Electron Microscopy Employing Ionic Liquid Bulletin of the Chemical Society of Japan 2013 86:153-158

15328 Fujii M, Kawai K, Egami Y, Araki N. Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation Sci Rep 2013 3:2385 PubMed ID: 23924974

15329 Muramatsu S, Tanaka S, Mogushi K, Adikrisna R, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Nakayama K, Tanaka H, Yamaoka S, Arii S. Visualization of stem cell features in human hepatocellular carcinoma reveals in vivo significance of tumor-host interaction and clinical course Hepatology 2013 58(1):218-28 PubMed ID: 23447025

15330 Nishimura M, Nii T, Trimova G, Miura S, Umezawa K, Ushiyama A, Kubota T. The NF-κB specific inhibitor DHMEQ prevents thrombus formation in a mouse model of antiphospholipid syndrome J Nephropathol 2013 2(2):114-21 PubMed ID: 24475437

15331 Hiroshi HAYASHI, Yosuke UJII, Seiji GODA, Naoyuki MATSUMOTO Effect of VCAM-1 on the Differentiation into Osteoclast Journal of Oral Tissue Engineering 2013 11:154-162

15332 Higashimura Y, Naito Y, Takagi T, Mizushima K, Hirai Y, Harusato A, Ohnogi H, Yamaji R, Inui H, Nakano Y, Yoshikawa T. Oligosaccharides from agar inhibit murine intestinal inflammation through the induction of heme oxygenase-1 expression J Gastroenterol 2013 48(8):897-909 PubMed ID: 23188093

15333 Tatsuya Murakami, Masashi Nakatani, Masahiro Kokubo, Hirotaka Nakatsuji, Mami Inada, Hiroshi Imahori, Masako Yudasaka, Sumio Iijima, Kunihiro Tsuchida Mechanism of Cell Interactions with Water-Dispersed Carbon Nanohorns Nanoscience and Nanotechnology Letters 2013 5:402-407

15334 Tanaka K, Ishihara T, Sugizaki T, Kobayashi D, Yamashita Y, Tahara K, Yamakawa N, Iijima K, Mogushi K, Tanaka H, Sato K, Suzuki H, Mizushima T. Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease Nat Commun 2013 4:2686 PubMed ID: 24189798

15335 Seikou Kim, Kouichi Yamamoto, Yusuke Nakamura, Yuichi Otoyo, Atsushi Yamatodani A Possible Mechanism of Cisplatin-Induced Tumor Necrosis Factor (TNF)-α Production in Murine Macrophages Pharmacology & Pharmacy 2013 4:146-151

15336 Tadahiro Etoh, Yong P. Kim, Masahiko Hayashi, Michiko Suzawa, Shiming Li, Chi-Tang Ho, Kanki Komiyama Inhibitory effect of a formulated extract from multiple citrus peels on LPS-induced inflammation in RAW 246.7 macrophages Functional Foods in Health and Disease 2013 3:242

15337 Phyu Phyu Khine Zar, Kozue Sakao, Fumio Hashimoto, Akiko Morishita, Makoto Fujii, Koji Wada, De-Xing Hou Antioxidant and anti-inflammatory activities of loquat (Eriobotrya japonica) tea Functional Foods in Health and Disease 2013 3:447

15773 Xi Yang, Yingnan Yang, Min Shi, Yuepeng Wang, Zhenya Zhang, Yifeng Lu Optimisation of Anthocyanin Extraction from Purple Pitaya and Verification of Antioxidant Properties, Antiproliferative Activity and Macrophage Proliferation Activity International Journal of Biology 2013 5

16086 Kawabata K, Sugiyama Y, Sakano T, Ohigashi H. Flavonols enhanced production of anti-inflammatory substance(s) by Bifidobacterium adolescentis: prebiotic actions of galangin, quercetin, and fisetin Biofactors 2013 39(4):422-9 PubMed ID: 23554103

7589 Funakoshi T, Yamashita K, Ichikawa N, Fukai M, Suzuki T, Goto R, Oura T, Kobayashi N, Katsurada T, Ichihara S, Ozaki M, Umezawa K, Todo S. A novel NF-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice. J Crohns Colitis 2012 6:215-25 PubMed ID: 22325176

7599 Takano K, Sato K, Negishi Y, Aramaki Y. Involvement of actin cytoskeleton in macrophage apoptosis induced by cationic liposomes. Arch. Biochem. Biophys. 2012 518:89-94 PubMed ID: 22203089

7608 Takahashi K, Sugiyama T, Tokoro S, Neri P, Mori H. Inhibition of interferon-γ-induced nitric oxide production by 10-hydroxy-trans-2-decenoic acid through inhibition of interferon regulatory factor-8 induction. Cell. Immunol. 2012 273:73-8

7609 Uto T, Morinaga O, Tanaka H, Shoyama Y. Analysis of the synergistic effect of glycyrrhizin and other constituents in licorice extract on lipopolysaccharide-induced nitric oxide production using knock-out extract. Biochem. Biophys. Res. Commun. 2012 417:473-8 PubMed ID: 22178686

7621 Nakagawa S, Arai Y, Kishida T, Hiraoka N, Tsuchida S, Inoue H, Sakai R, Mazda O, Kubo T. Lansoprazole inhibits nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells. Inflammation 2012 35:1062-8

7639 Uto T, Qin GW, Morinaga O, Shoyama Y. 17-Hydroxy-jolkinolide B, a diterpenoid from Euphorbia fischeriana, inhibits inflammatory mediators but activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine macrophages. Int. Immunopharmacol. 2012 12:101-9 PubMed ID: 22080918

7667 Uchida M, Oyanagi E, Kremenik MJ, Sasaki J, Yano H. Interferon-beta, but not tumor necrosis factor-alpha, production in response to poly I:C is maintained despite exhaustive exercise in mice. J Physiol Sci 2012 62:59-62 PubMed ID: 21968540

7678 Sugiyama T, Takahashi K, Tokoro S, Gotou T, Neri P, Mori H. Inhibitory effect of 10-hydroxy-trans-2-decenoic acid on LPS-induced IL-6 production via reducing IκB-ζ expression. Innate Immun 2012 18:429-37 PubMed ID: 21948282

4881 Honda H, Nagai Y, Matsunaga T, Saitoh S, Akashi-Takamura S, Hayashi H, Fujii I, Miyake K, Muraguchi A, Takatsu K. Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner. J Leukoc Biol 2012 91(6):967-76 PubMed ID: 22422925

5417 Echigo R, Shimohata N, Karatsu K, Yano F, Kayasuga-Kariya Y, Fujisawa A, Ohto T, Kita Y, Nakamura M, Suzuki S, Mochizuki M, Shimizu T, Chung UI, Sasaki N. Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage. J Transl Med 2012 10:80 PubMed ID: 22546323

6552 Takarada T, Takarada-Iemata M, Takahata Y, Yamada D, Yamamoto T, Nakamura Y, Hinoi E, Yoneda Y. Osteoclastogenesis is negatively regulated by D-serine produced by osteoblasts. J Cell Physiol 2012 227(10):3477-87 PubMed ID: 22252936

9092 Hiroyasu Tsutsuki, Kinnosuke Yahiro, Kotaro Suzuki, Akira Suto, Kohei Ogura, Sayaka Nagasawa, Hideshi Ihara, Takeshi Shimizu, Hiroshi Nakajima, Joel Moss, Masatoshi Noda Subtilase Cytotoxin Enhances Escherichia Coli Survival in Macrophages by Suppression of Nitric Oxide Production Through the Inhibition of NF-κB Activation Infect Immun 2012 80 (11), 3939-51 PubMed ID: 22949549

9246 Yoshikazu Morita, Aiko Ono-Ohmachi, Satoshi Higurashi, Hiroaki Matsuyama, Atsushi Serizawa, Tatsuo Takeya The bone-strengthening activity of milk basic protein is not dependent on lactoferrin International Dairy Journal 2012 27:40-46

10965 Makoto Ayaori, Emi Yakushiji, Masatsune Ogura, Kazuhiro Nakaya, Tetsuya Hisada, Harumi Uto-Kondo, Shunichi Takiguchi, Yoshio Terao, Makoto Sasaki, Tomohiro Komatsu, Maki Iizuka, Makiko Yogo, Yoshinari Uehara, Hiroyuki Kagechika, Tsuyoshi Nakanishi, Katsunori Ikewaki Retinoic acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages Biochim Biophys Acta 2012 1821(4):561-72 PubMed ID: 22353356

15342 Toshiya KAWASAKI, Seiji GODA, Naoyuki MATSUMOTO Effect of Akt on the Differentiation into Osteoclasts Caused by RANKL Stimulation Journal of Oral Tissue Engineering 2012 10:67-76

15343 Iizuka M, Ayaori M, Uto-Kondo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Sasaki M, Komatsu T, Yogo M, Kishimoto Y, Kondo K, Ikewaki K. Astaxanthin enhances ATP-binding cassette transporter A1/G1 expressions and cholesterol efflux from macrophages J Nutr Sci Vitaminol (Tokyo) 2012 58(2):96-104 PubMed ID: 22790567

15344 Kakutani R, Adachi Y, Takata H, Kuriki T, Ohno N. Essential role of Toll-like receptor 2 in macrophage activation by glycogen Glycobiology 2012 22(1):146-59 PubMed ID: 21873606

15345 Miyashita K, Oyama T, Sakuta T, Tokuda M, Torii M. Anandamide induces matrix metalloproteinase-2 production through cannabinoid-1 receptor and transient receptor potential vanilloid-1 in human dental pulp cells in culture J Endod 2012 38(6):786-90 PubMed ID: 22595113

15346 Choi SH, Ahn JB, Kozukue N, Kim HJ, Nishitani Y, Zhang L, Mizuno M, Levin CE, Friedman M. Structure-activity relationships of α-, β(1)-, γ-, and δ-tomatine and tomatidine against human breast (MDA-MB-231), gastric (KATO-III), and prostate (PC3) cancer cells J Agric Food Chem 2012 60(15):3891-9 PubMed ID: 22482398

7558 Bandow K, Kusuyama J, Shamoto M, Kakimoto K, Ohnishi T, Matsuguchi T. LPS-induced chemokine expression in both MyD88-dependent and -independent manners is regulated by Cot/Tpl2-ERK axis in macrophages FEBS Lett 2012 586(10):1540-6 PubMed ID: 22673523

7633 Yamamoto H, Abe Y, Miyazato A, Tanno D, Tanaka M, Miyasaka T, Ishii K, Kawakami K. Cryptococcus neoformans suppresses the activation of bone marrow-derived dendritic cells stimulated with its own DNA, but not with DNA from other fungi. FEMS Immunol. Med. Microbiol. 2011 63:363-72 PubMed ID: 22092563

7702 Chen J, Qin S, Xiao J, Tanigawa S, Uto T, Hashimoto F, Fujii M, Hou DX. A genome-wide microarray highlights the antiinflammatory genes targeted by oolong tea theasinensin A in macrophages. Nutr Cancer 2011 63:1064-73 PubMed ID: 21864060

7704 Ozasa H, Ayaori M, Iizuka M, Terao Y, Uto-Kondo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Uehara Y, Ogura M, Sasaki M, Komatsu T, Horii S, Mochizuki S, Yoshimura M, Ikewaki K. Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: findings from in vitro and ex vivo studies. Atherosclerosis 2011 219:141-50 PubMed ID: 21862012

7725 Sakamoto T, Yamaguchi Y, Goto T, Takahashi N, Kawada T. An in vitro analysis system using a fluorescence protein reporter for evaluating anti-inflammatory effects in macrophages. Biosci. Biotechnol. Biochem. 2011 75:1582-7 PubMed ID: 21821941

7745 Itoh T, Hamada N, Terazawa R, Ito M, Ohno K, Ichihara M, Nozawa Y, Ito M. Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages. Biochem. Biophys. Res. Commun. 2011 411:143-9 PubMed ID: 21723254

7750 Fujimoto A, Akifusa S, Hirofuji T, Yamashita Y. Involvement of suppressor of cytokine signaling-1 in globular adiponectin-induced granulocyte colony-stimulating factor in RAW 264 cell. Mol. Immunol. 2011 48:2052-8 PubMed ID: 21764457

7789 Abiko Y, Miura T, Phuc BH, Shinkai Y, Kumagai Y. Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole. Toxicol. Appl. Pharmacol. 2011 255:32-9 PubMed ID: 21651925

7794 Haque A, Noman AS, Koide N, Odkhuu E, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T. An ADP ribosylation factor-GTPase activating protein negatively regulates the production of proinflammatory mediators in response to lipopolysaccharide. Cancer Immunol. Immunother. 2011 60:1439-46 PubMed ID: 21644032

7850 Egusa H, Doi M, Saeki M, Fukuyasu S, Akashi Y, Yokota Y, Yatani H, Kamisaki Y. The small molecule harmine regulates NFATc1 and Id2 expression in osteoclast progenitor cells. Bone 2011 49:264-74 PubMed ID: 21504804

7851 Akagi T, Shima F, Akashi M. Intracellular degradation and distribution of protein-encapsulated amphiphilic poly(amino acid) nanoparticles. Biomaterials 2011 32:4959-67 PubMed ID: 21482432

7901 Yamazaki Y, Kawano Y. Inhibitory effects of herbal alkaloids on the tumor necrosis factor-α and nitric oxide production in lipopolysaccharide-stimulated RAW264 macrophages. Chem. Pharm. Bull. 2011 59:388-91 PubMed ID: 21372424

7921 Kurio N, Shimo T, Fukazawa T, Takaoka M, Okui T, Hassan NM, Honami T, Hatakeyama S, Ikeda M, Naomoto Y, Sasaki A. Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo. Exp. Cell Res. 2011 317:1134-46 PubMed ID: 21338601

7949 Arisaka M, Takano K, Negishi Y, Arima H, Aramaki Y. Involvement of lipid rafts in macrophage apoptosis induced by cationic liposomes. Arch. Biochem. Biophys. 2011 508:72-7 PubMed ID: 21315683

7966 Ichioka M, Suganami T, Tsuda N, Shirakawa I, Hirata Y, Satoh-Asahara N, Shimoda Y, Tanaka M, Kim-Saijo M, Miyamoto Y, Kamei Y, Sata M, Ogawa Y. Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans. Diabetes 2011 60:819-26 PubMed ID: 21282371

8010 Haque A, Koide N, Iftakhar-E-Khuda I, Noman AS, Odkhuu E, Badamtseren B, Naiki Y, Komatsu T, Yoshida T, Yokochi T. Flavopiridol inhibits lipopolysaccharide-induced TNF-α production through inactivation of nuclear factor-κB and mitogen-activated protein kinases in the MyD88-dependent pathway. Microbiol. Immunol. 2011 55:160-7 PubMed ID: 21204955

8052 Miyazaki T, Miyauchi S, Anada T, Imaizumi H, Suzuki O. Evaluation of osteoclastic resorption activity using calcium phosphate coating combined with labeled polyanion. Anal. Biochem. 2011 410:7-12 PubMed ID: 21078287

8066 Yonezawa T, Hasegawa S, Asai M, Ninomiya T, Sasaki T, Cha BY, Teruya T, Ozawa H, Yagasaki K, Nagai K, Woo JT. Harmine, a β-carboline alkaloid, inhibits osteoclast differentiation and bone resorption in vitro and in vivo. Eur. J. Pharmacol. 2011 650:511-8 PubMed ID: 21047508

8067 Kamio N, Akifusa S, Yamashita Y. Diacylglycerol kinase alpha regulates globular adiponectin-induced reactive oxygen species. Free Radic. Res. 2011 45:336-41 PubMed ID: 21034360

8135 Fukata N, Uchida K, Kusuda T, Koyabu M, Miyoshi H, Fukui T, Matsushita M, Nishio A, Tabata Y, Okazaki K. The effective therapy of cyclosporine A with drug delivery system in experimental colitis. J Drug Target 2011 19:458-67 PubMed ID: 20804404

8415 Tumurkhuu G, Koide N, Hiwasa T, Ookoshi M, Dagvadorj J, Abu Shadat Mohammod Noman, Iftakhar-E-Khuda I, Naiki Y, Komatsu T, Yoshida T, Yokochi T. ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock. Innate Immun 2011 17:97-105 PubMed ID: 20023007

8455 Shikama Y, Kuroishi T, Nagai Y, Iwakura Y, Shimauchi H, Takada H, Sugawara S, Endo Y. Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1). Innate Immun 2011 17:3-15 PubMed ID: 19897531

15296 Oka H, Mori M, Kihara H. F-spondin inhibits migration and differentiation of osteoclastic precursors J Periodontol 2011 82(12):1776-83 PubMed ID: 21488757

15348 Oshima H, Popivanova BK, Oguma K, Kong D, Ishikawa TO, Oshima M. Activation of epidermal growth factor receptor signaling by the prostaglandin E(2) receptor EP4 pathway during gastric tumorigenesis Cancer Sci 2011 102(4):713-9 PubMed ID: 21205091

15349 Sugiyama K, Kawakami H, Kamata Y, Sugita-Konishi Y. Effect of a combination of deoxynivalenol and nivalenol on lipopolisaccharide-induced nitric oxide production by mouse macrophages Mycotoxin Res 2011 27(1):57-62 PubMed ID: 23605623

15350 Kizaki T, Maegawa T, Sakurai T, Ogasawara JE, Ookawara T, Oh-ishi S, Izawa T, Haga S, Ohno H. Voluntary exercise attenuates obesity-associated inflammation through ghrelin expressed in macrophages Biochem Biophys Res Commun 2011 413(3):454-9 PubMed ID: 21907183

15351 Terao Y, Ayaori M, Ogura M, Yakushiji E, Uto-Kondo H, Hisada T, Ozasa H, Takiguchi S, Nakaya K, Sasaki M, Komatsu T, Iizuka M, Horii S, Mochizuki S, Yoshimura M, Ikewaki K. Effect of sulfonylurea agents on reverse cholesterol transport in vitro and vivo J Atheroscler Thromb 2011 18(6):513-30 PubMed ID: 21636950

15352 Eisuke DOMAE, Yumiko OGAWA, Osamu TAKEUCHI, Yosuke UJII, Yu KATO, Toshiya KAWASAKI, Hiroshi HAYASHI, Reiko KOMASA, Naochika DOMAE, Seiji GODA, Takashi IKEO The Effect of Lysenin on the Differentiation into Osteoclast Cells Journal of Oral Tissue Engineering 2011 9:3-9

15353 Ishijima Y, Kawamura T, Kimura A, Kohno A, Okada T, Tsuji T, Watanabe Y. Toll-like receptor 4-dependent adjuvant activity of Kakkon-to extract exists in the high molecular weight polysaccharide fraction Int J Immunopathol Pharmacol 2011 24(1):43-54 PubMed ID: 21496386

15354 Mukai S, Kitazawa R, Ishii J, Kondo T, Hakozaki A, Horiuchi K, Haraguch R, Mori K, Kitazawa S. Identification and analysis of function of a novel splicing variant of mouse receptor activator of NF-κB Mol Cell Biochem 2011 350(1-2):29-38 PubMed ID: 21153864

15355 Takayuki Anno, Keiichi Motoyama, Taishi Higashi, Fumitoshi Hirayama, Kaneto Uekama, Hidetoshi Arima Preparation and evaluation of polyamidoamine dendrimer (G2)/branched-β-cyclodextrin conjugate as a novel gene transfer carrier Journal of Inclusion Phenomena and Macrocyclic Chemistry 2011 70:339-344

15356 Cui H, Okuhira K, Ohoka N, Naito M, Kagechika H, Hirose A, Nishimaki-Mogami T. Tributyltin chloride induces ABCA1 expression and apolipoprotein A-I-mediated cellular cholesterol efflux by activating LXRα/RXR Biochem Pharmacol 2011 81(6):819-24 PubMed ID: 21219878

15357 Di Guan, Zhenya Zhang, Yingnan Yang, Guoqing Xing, Jiqiang Liu Immunomodulatory Activity of Polysaccharide from the Roots of Actinidia kolomikta on Macrophages International Journal of Biology 2011 3

15359 Aoyagi Y, Adachi Y, Ozawa K, Yokomizo C, Gui MY, Jin YR, Li XW, Ohno N, Takeya K. Synthesis of rabdokunmin C analogues and their inhibitory effect on NF-κB activation Bioorg Med Chem 2011 19(7):2450-7 PubMed ID: 21393004

8050 Hou DX, Masuzaki S, Tanigawa S, Hashimoto F, Chen J, Sogo T, Fujii M. Oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (LPS)-activated mouse macrophages: structure-activity relationship and molecular mechanisms. J. Agric. Food Chem. 2010 58:12735-43 PubMed ID: 21082860

8058 Oshima H, Hioki K, Popivanova BK, Oguma K, Van Rooijen N, Ishikawa TO, Oshima M. Prostaglandin E? signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors. Gastroenterology 2010 140:596-607.e7 PubMed ID: 21070778

8060 Ueda H, Ippoushi K, Takeuchi A. Repeated oral administration of a squeezed ginger (Zingiber officinale) extract augmented the serum corticosterone level and had anti-inflammatory properties. Biosci. Biotechnol. Biochem. 2010 74:2248-52 PubMed ID: 21071834

8085 Sakagami H, Zhou L, Kawano M, Thet MM, Tanaka S, Machino M, Amano S, Kuroshita R, Watanabe S, Chu Q, Wang QT, Kanamoto T, Terakubo S, Nakashima H, Sekine K, Shirataki Y, Zhang CH, Uesawa Y, Mohri K, Kitajima M, Oizumi H, Oizumi T. Multiple biological complex of alkaline extract of the leaves of Sasa senanensis Rehder. In Vivo 2010 24:735-43 PubMed ID: 20952742

8102 Lee JW, Mase N, Yonezawa T, Seo HJ, Jeon WB, Cha BY, Nagai K, Woo JT. Palmatine attenuates osteoclast differentiation and function through inhibition of receptor activator of nuclear factor-κb ligand expression in osteoblast cells. Biol. Pharm. Bull. 2010 33:1733-9 PubMed ID: 20930384

8113 Okui T, Shimo T, Fukazawa T, Kurio N, Hassan NM, Honami T, Takaoka M, Naomoto Y, Sasaki A. Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction. Mol. Cancer Ther. 2010 9:2960-9 PubMed ID: 20858724

8136 Shikama Y, Nagai Y, Okada S, Oizumi T, Shimauchi H, Sugawara S, Endo Y. Pro-IL-1β accumulation in macrophages by alendronate and its prevention by clodronate. Toxicol. Lett. 2010 199:123-8 PubMed ID: 20804833

8148 Nakaya K, Ayaori M, Uto-Kondo H, Hisada T, Ogura M, Yakushiji E, Takiguchi S, Terao Y, Ozasa H, Sasaki M, Komatsu T, Ohsuzu F, Ikewaki K. Cilostazol enhances macrophage reverse cholesterol transport in vitro and in vivo. Atherosclerosis 2010 213:135-41 PubMed ID: 20723893

8160 Kotani H, Tanabe H, Mizukami H, Makishima M, Inoue M. Identification of a naturally occurring rexinoid, honokiol, that activates the retinoid X receptor. J. Nat. Prod. 2010 73:1332-6 PubMed ID: 20695472

8168 Yoshikawa K, Kokudo N, Hashimoto T, Yamamoto K, Inose T, Kimura T. Novel phthalide compounds from Sparassis crispa (Hanabiratake), Hanabiratakelide A-C, exhibiting anti-cancer related activity. Biol. Pharm. Bull. 2010 33:1355-9 PubMed ID: 20686231

8181 Nakatsuka R, Nozaki T, Shinohara M, Ohura K. Dilazep decreases lipopolysaccharide-induced nitric oxide and TNF-alpha synthesis in RAW 264 cells. J. Pharmacol. Sci. 2010 113:271-5 PubMed ID: 20647687

8208 Yano H, Uchida M, Nakai R, Ishida K, Kato Y, Kawanishi N, Shiva D. Exhaustive exercise reduces TNF-α and IFN-α production in response to R-848 via toll-like receptor 7 in mice. Eur. J. Appl. Physiol. 2010 110:797-803 PubMed ID: 20602110

8210 Shadat NM, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T. Retinoblastoma protein-interacting zinc finger 1 (RIZ1) regulates the proliferation of monocytic leukemia cells via activation of p53. Cancer Invest. 2010 28:806-12 PubMed ID: 20594067

8214 Sakai H, Moriura Y, Notomi T, Kawawaki J, Ohnishi K, Kuno M. Phospholipase C-dependent Ca2+-sensing pathways leading to endocytosis and inhibition of the plasma membrane vacuolar H+-ATPase in osteoclasts. Am. J. Physiol., Cell Physiol. 2010 299:C570-8 PubMed ID: 20592242

8221 Yasuzaki Y, Yamada Y, Harashima H. Mitochondrial matrix delivery using MITO-Porter, a liposome-based carrier that specifies fusion with mitochondrial membranes. Biochem. Biophys. Res. Commun. 2010 397:181-6 PubMed ID: 20580633

8224 Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nonaka K, Yamashita Y. Involvement of the JAK-STAT pathway and SOCS3 in the regulation of adiponectin-generated reactive oxygen species in murine macrophage RAW 264 cells. J. Cell. Biochem. 2010 111:597-606 PubMed ID: 20564237

8228 Kato Y, Koide N, Komatsu T, Tumurkhuu G, Dagvadorj J, Kato K, Yokochi T. Metformin attenuates production of nitric oxide in response to lipopolysaccharide by inhibiting MyD88-independent pathway. Horm. Metab. Res. 2010 42:632-6 PubMed ID: 20560107

8229 Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T. Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation. Cell. Immunol. 2010 264:114-8 PubMed ID: 20557878

8249 Ohata S, Moriyama C, Yamashita A, Nishida T, Kusumoto C, Mochida S, Minami Y, Nakada J, Shomori K, Inagaki Y, Ohta Y, Matsura T. Polaprezinc Protects Mice against Endotoxin Shock. J Clin Biochem Nutr 2010 46:234-43 PubMed ID: 20490319

8258 Yamaguchi N, Hamachi T, Kamio N, Akifusa S, Masuda K, Nakamura Y, Nonaka K, Maeda K, Hanazawa S, Yamashita Y. Expression levels of adiponectin receptors and periodontitis. J. Periodont. Res. 2010 45:296-300 PubMed ID: 20470261

8273 Xiao G, Miyazato A, Abe Y, Zhang T, Nakamura K, Inden K, Tanaka M, Tanno D, Miyasaka T, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Yamamoto N, Kunishima H, Hirakata Y, Kaku M, Kawakami K. Activation of myeloid dendritic cells by deoxynucleic acids from Cordyceps sinensis via a Toll-like receptor 9-dependent pathway. Cell. Immunol. 2010 263:241-50 PubMed ID: 20451901

8282 Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T. Retinoblastoma protein-interacting zinc finger 1 (RIZ1) participates in RANKL-induced osteoclast formation via regulation of NFATc1 expression. Immunol. Lett. 2010 131:166-9 PubMed ID: 20417662

8286 Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T. Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS. Immunology 2010 131:59-66 PubMed ID: 20406300

8335 Kitagawa Y, Tohya Y, Ike F, Kajita A, Park SJ, Ishii Y, Kyuwa S, Yoshikawa Y. Indirect ELISA and indirect immunofluorescent antibody assay for detecting the antibody against murine norovirus S7 in mice. Exp. Anim. 2010 59:47-55 PubMed ID: 20224169

8368 Shimoda H, Shan SJ, Tanaka J, Seki A, Seo JW, Kasajima N, Tamura S, Ke Y, Murakami N. Anti-inflammatory properties of red ginger (Zingiber officinale var. Rubra) extract and suppression of nitric oxide production by its constituents. J Med Food 2010 13:156-62 PubMed ID: 20136450

8369 Tsukamoto H, Fukudome K, Takao S, Tsuneyoshi N, Kimoto M. Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells. Int. Immunol. 2010 22:271-80 PubMed ID: 20133493

8372 Arisaka M, Nakamura T, Yamada A, Negishi Y, Aramaki Y. Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells. FEBS Lett. 2010 584:1016-20 PubMed ID: 20122929

8373 Hakozaki A, Yoda M, Tohmonda T, Furukawa M, Hikata T, Uchikawa S, Takaishi H, Matsumoto M, Chiba K, Horiuchi K, Toyama Y. Receptor activator of NF-kappaB (RANK) ligand induces ectodomain shedding of RANK in murine RAW264.7 macrophages. J. Immunol. 2010 184:2442-8 PubMed ID: 20118276

8396 Suzuki T, Chang MO, Kitajima M, Takaku H. Baculovirus activates murine dendritic cells and induces non-specific NK cell and T cell immune responses. Cell. Immunol. 2010 262:35-43 PubMed ID: 20060108

8426 Hirai S, Uemura T, Mizoguchi N, Lee JY, Taketani K, Nakano Y, Hoshino S, Tsuge N, Narukami T, Yu R, Takahashi N, Kawada T. Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages. Mol Nutr Food Res 2010 54:797-804 PubMed ID: 19998383

8456 Fujimoto A, Akifusa S, Kamio N, Hirofuji T, Nonaka K, Yamashita Y. Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species. Free Radic. Res. 2010 44:128-34 PubMed ID: 19886750

8462 Matsubara T, Ikeda F, Hata K, Nakanishi M, Okada M, Yasuda H, Nishimura R, Yoneda T. Cbp recruitment of Csk into lipid rafts is critical to c-Src kinase activity and bone resorption in osteoclasts. J. Bone Miner. Res. 2010 25:1068-76 PubMed ID: 19874196

8465 Sugiyama K, Muroi M, Tanamoto K, Nishijima M, Sugita-Konishi Y. Deoxynivalenol and nivalenol inhibit lipopolysaccharide-induced nitric oxide production by mouse macrophage cells. Toxicol. Lett. 2010 192:150-4 PubMed ID: 19857559

8488 Kishimoto Y, Tani M, Uto-Kondo H, Iizuka M, Saita E, Sone H, Kurata H, Kondo K. Astaxanthin suppresses scavenger receptor expression and matrix metalloproteinase activity in macrophages. Eur J Nutr 2010 49:119-26 PubMed ID: 19784539

5872 Chen J, Uto T, Tanigawa S, Yamada-Kato T, Fujii M, Hou DX. Microarray-based determination of anti-inflammatory genes targeted by 6-(methylsulfinyl)hexyl isothiocyanate in macrophages. Exp Ther Med 2010 1(1):33-40 PubMed ID: 23136589

8207 Kaori Yoshino, Kaoru Saijo, Chikako Noro and Yukio Nakamura Development of a simple method to determine the mouse strain from which cultured cell lines originated Interdisciplinary Bio Central 2010 2:0014

8268 Miyazaki T, Miyauchi S, Tawada A, Anada T, Suzuki O. Effect of chondroitin sulfate-E on the osteoclastic differentiation of RAW264 cells. Dent Mater J 2010 29(4):403-10 PubMed ID: 20610874

15360 Ii H, Imai T, Yaegaki K, Irie K, Ekuni D, Morita M. Oral malodorous compound induces osteoclast differentiation without receptor activator of nuclear factor κB ligand J Periodontol 2010 81(11):1691-7 PubMed ID: 20583917

15361 Uto T, Suangkaew N, Morinaga O, Kariyazono H, Oiso S, Shoyama Y. Eriobotryae folium extract suppresses LPS-induced iNOS and COX-2 expression by inhibition of NF-kappaB and MAPK activation in murine macrophages Am J Chin Med 2010 38(5):985-94 PubMed ID: 20821828

15362 Sasaki M, Miyakoshi M, Sato Y, Nakanuma Y. Modulation of the microenvironment by senescent biliary epithelial cells may be involved in the pathogenesis of primary biliary cirrhosis J Hepatol 2010 53(2):318-25 PubMed ID: 20570384

15363 B. Sritularak, A. Tantituvanont1, P. Chanvorachote1, K. Meksawan1, T. Miyamoto2, Y. Kohno and K. Likhitwitayawuid Flavonoids with free radical scavenging activity and nitric oxide inhibitory effect from the stem bark of Artocarpus gomezianus Journal of Medicinal Plants Research 2010 4:387-392

15364 Takeichi SAKATA, Seiji GODA, Yumiko OGAWA, Takashi IKEO, Shosuke MORITA β1-Integrin-Dependent Macrophage Migration is Regulated by MAP Kinase Journal of Oral Tissue Engineering 2010 8:124-132

8359 Lee JW, Ahn JY, Hasegawa S, Cha BY, Yonezawa T, Nagai K, Seo HJ, Jeon WB, Woo JT. Inhibitory effect of luteolin on osteoclast differentiation and function. Cytotechnology 2009 61:125-34 PubMed ID: 20162352

8495 Katsuura S, Imamura T, Bando N, Yamanishi R. beta-Carotene and beta-cryptoxanthin but not lutein evoke redox and immune changes in RAW264 murine macrophages. Mol Nutr Food Res 2009 53:1396-405 PubMed ID: 19760679

8549 Shioiri T, Muroi M, Hatao F, Nishida M, Ogawa T, Mimura Y, Seto Y, Kaminishi M, Tanamoto K. Caspase-3 is activated and rapidly released from human umbilical vein endothelial cells in response to lipopolysaccharide. Biochim. Biophys. Acta 2009 1792:1011-8 PubMed ID: 19559790

8550 Kamio N, Akifusa S, Yamaguchi N, Nonaka K, Yamashita Y. Anti-inflammatory activity of a globular adiponectin function on RAW 264 cells stimulated by lipopolysaccharide from Aggregatibacter actinomycetemcomitans. FEMS Immunol. Med. Microbiol. 2009 56:241-7 PubMed ID: 19552715

8551 Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T. Thalidomide inhibits lipopolysaccharide-induced nitric oxide production and prevents lipopolysaccharide-mediated lethality in mice. FEMS Immunol. Med. Microbiol. 2009 56:204-11 PubMed ID: 19538513

8578 Miyazato A, Nakamura K, Yamamoto N, Mora-Montes HM, Tanaka M, Abe Y, Tanno D, Inden K, Gang X, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Mitsutake K, Gow NA, Kaku M, Kawakami K. Toll-like receptor 9-dependent activation of myeloid dendritic cells by Deoxynucleic acids from Candida albicans. Infect. Immun. 2009 77:3056-64 PubMed ID: 19433551

8589 Seddek Al, Mahmoud ME, Shiina T, Hirayama H, Iwami M, Miyazawa S, Nikami H, Takewaki T, Shimizu Y. Extract from Calotropis procera latex activates murine macrophages. J Nat Med 2009 63:297-303 PubMed ID: 19399577

8637 Tomimori Y, Mori K, Koide M, Nakamichi Y, Ninomiya T, Udagawa N, Yasuda H. Evaluation of pharmaceuticals with a novel 50-hour animal model of bone loss. J. Bone Miner. Res. 2009 24:1194-205 PubMed ID: 19257825

8640 Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Nishihara T, Yamashita Y. Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2. Free Radic. Biol. Med. 2009 46:1308-16 PubMed ID: 19250964

8641 Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y. Involvement of Ca(2+) in globular adiponectin-induced reactive oxygen species. Biochem. Biophys. Res. Commun. 2009 381:649-53 PubMed ID: 19249286

8642 Hassan F, Islam S, Tumurkhuu G, Dagvadorj J, Naiki Y, Komatsu T, Koide N, Yoshida T, Yokochi T. Involvement of interleukin-1 receptor-associated kinase (IRAK)-M in toll-like receptor (TLR) 7-mediated tolerance in RAW 264.7 macrophage-like cells. Cell. Immunol. 2009 256:99-103 PubMed ID: 19251253

8648 Kasugai C, Morikawa A, Naiki Y, Koide N, Komatsu T, Yoshida T, Yokochi T. Concanavalin A induces formation of osteoclast-like cells in RAW 264.7 mouse macrophage cells. Immunopharmacol Immunotoxicol 2009 31:103-7 PubMed ID: 19234958

8654 Iftakhar-E-Khuda I, Koide N, Hassan F, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T. Novel mechanism of U18666A-induced tumour necrosis factor-alpha production in RAW 264.7 macrophage cells. Clin. Exp. Immunol. 2009 155:552-8 PubMed ID: 19220841

8663 Noman AS, Koide N, Hassan F, I-E-Khuda I, Dagvadorj J, Tumurkhuu G, Islam S, Naiki Y, Yoshida T, Yokochi T. Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression. Innate Immun 2009 15:33-41 PubMed ID: 19201823

8691 Inden K, Kaneko J, Miyazato A, Yamamoto N, Mouri S, Shibuya Y, Nakamura K, Aoyagi T, Hatta M, Kunishima H, Hirakata Y, Itoh Y, Kaku M, Kawakami K. Toll-like receptor 4-dependent activation of myeloid dendritic cells by leukocidin of Staphylococcus aureus. Microbes Infect. 2009 11:245-53 PubMed ID: 19111627

8739 Nakamura T, Kodama N, Arai Y, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ishikawa T, Ueno K, Yano S. Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7. J Nat Med 2009 63:21-7 PubMed ID: 18636311

8740 Nakamura T, Kodama N, Kumamoto T, Higuchi Y, Chaichantipyuth C, Ueno K, Ishikawa T, Yano S. Inhibitory effect of the extracts from Thai medicinal plants on iNOS expression in mouse macrophage RAW 264.7. J Nat Med 2009 63:107-10 PubMed ID: 18626726

8742 Nakamura T, Kodama N, Oda M, Tsuchiya S, Arai Y, Kumamoto T, Ishikawa T, Ueno K, Yano S. The structure-activity relationship between oxycoumarin derivatives showing inhibitory effects on iNOS in mouse macrophage RAW264.7 cells. J Nat Med 2009 63:15-20 PubMed ID: 18607531

10145 Murakami M, Kawachi H, Ogawa K, Nishino Y, Funaba M. Receptor expression modulates the specificity of transforming growth factor-beta signaling pathways. Genes Cells 2009 14(4):469-82 PubMed ID: 19335617

8170 Tsuji M, Yamamoto H, Sato T, Mizuha Y, Kawai Y, Taketani Y, Kato S, Terao J, Inakuma T, Takeda E. Dietary quercetin inhibits bone loss without effect on the uterus in ovariectomized mice. J Bone Miner Metab 2009 27(6):673-81 PubMed ID: 19495926

11020 Masayuki TAIRA et al DNA Microarray Analyses of the Effects of LPS-stimulation and IC50 Nickel Ions on Gene Expressions of Mouse Macrophage-like Cell Line RAW264 Nano Biomedicine 2009 1:59-69

12295 Ken Shirato, Takako Kizaki, Takuya Sakurai, Jun-Etsu Ogasawara, Yoshinaga Ishibashi, Takehiko Iijima, Chikako Okada, Izumi Noguchi, Kazuhiko Imaizumi, Naoyuki Taniguchi, Hideki Ohno Hypoxia-inducible factor-1alpha suppresses the expression of macrophage scavenger receptor 1 Pflugers Arch 2009 459(1):93-103 PubMed ID: 19641936

15368 Namba T, Tanaka K, Ito Y, Ishihara T, Hoshino T, Gotoh T, Endo M, Sato K, Mizushima T. Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis Am J Pathol 2009 174(5):1786-98 PubMed ID: 19359519

15369 Iigo M, Alexander DB, Long N, Xu J, Fukamachi K, Futakuchi M, Takase M, Tsuda H. Anticarcinogenesis pathways activated by bovine lactoferrin in the murine small intestine Biochimie 2009 91(1):86-101 PubMed ID: 18634843

15370 Aoyama T, Takeshita K, Kikuchi R, Yamamoto K, Cheng XW, Liao JK, Murohara T. gamma-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice Biochem Biophys Res Commun 2009 383(2):216-21 PubMed ID: 19345673

16614 Kajiura T, Takeda T, Sakata S, Sakamoto M, Hashimoto M, Suzuki H, Suzuki M, Benno Y. Change of intestinal microbiota with elemental diet and its impact on therapeutic effects in a murine model of chronic colitis Dig Dis Sci 2009 54(9):1892-900 PubMed ID: 19058004

8731 Akifusa S, Kamio N, Shimazaki Y, Yamaguchi N, Yamashita Y. Regulation of globular adiponectin-induced apoptosis by reactive oxygen/nitrogen species in RAW264 macrophages. Free Radic. Biol. Med. 2008 45:1326-39 PubMed ID: 18775488

8754 Yoshida H, Kwon AH, Habara K, Yamada M, Kaibori M, Kamiyama Y, Nishizawa M, Ito S, Okumura T. Edaravone inhibits the induction of iNOS gene expression at transcriptional and posttranscriptional steps in murine macrophages. Shock 2008 30:734-9 PubMed ID: 18496239

5375 Nishida K, Kuchiiwa S, Oiso S, Futagawa T, Masuda S, Takeda Y, Yamada K. Up-regulation of matrix metalloproteinase-3 in the dorsal root ganglion of rats with paclitaxel-induced neuropathy. Cancer Sci 2008 99(8):1618-25 PubMed ID: 18754875

3578 Ando M, Tu W, Nishijima K, Iijima S. Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs. Biochem Biophys Res Commun 2008 369(3):878-83 PubMed ID: 18325328

6521 Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H. Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9. J Biol Chem 2008 283(36):24682-9 PubMed ID: 18617520

13756 Murakami M, Kondo S, Funaba M. Expression and function of alternative splice variants of the mouse TGF-beta type I receptor Cell Biol Int 2008 32(7):848-54 PubMed ID: 18474439

13958 Kawanishi N, Tanaka Y, Kato Y, Shiva D, Yano H. Lipopolysaccharide-induced monocyte chemotactic protein-1 is enhanced by suppression of nitric oxide production, which depends on poor CD14 expression on the surface of skeletal muscle Cell Biochem Funct 2008 26(4):486-9 PubMed ID: 18383566

15372 Ishii J, Kitazawa R, Mori K, McHugh KP, Morii E, Kondo T, Kitazawa S. Lipopolysaccharide suppresses RANK gene expression in macrophages by down-regulating PU.1 and MITF J Cell Biochem 2008 105(3):896-904 PubMed ID: 18759249

15373 Yumiko Ogawa, Seiji Goda, Shosuke Morita The Effect of Methyl-β-cyclodextrin on the Differentiation of RAW264 Cells into Osteoclasts Oral Science International 2008 5:15-23

15375 Ken-ichiro Minato Immunomodulation Activity of a Polysaccharide Fraction of a Culinary-Medicinal Mushroom, Pleurotus citrinopileatus Singer (Agaricomycetideae), in Vitro International Journal of Medicinal Mushrooms 2008 10:235-244

15376 Oguma K, Oshima H, Aoki M, Uchio R, Naka K, Nakamura S, Hirao A, Saya H, Taketo MM, Oshima M. Activated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells EMBO J 2008 27(12):1671-81 PubMed ID: 18511911

15377 Ryo Kakutani, Yoshiyuki Adachi, Hideki Kajiura, Hiroki Takata, Naohito Ohno, Takashi Kuriki Stimulation of macrophage by enzymatically synthesized glycogen: the relationship between structure and biological activity Biocatalysis and Biotransformation 2008 26:152-160

16649 Yeh CM, Yeh CK, Hsu XY, Luo QM, Lin MY. Extracellular expression of a functional recombinant Ganoderma lucidium immunomodulatory protein by Bacillus subtilis and Lactococcus lactis Appl Environ Microbiol 2008 74(4):1039-49 PubMed ID: 18156317

8815 Taira M, Sasaki K, Saitoh S, Nezu T, Sasaki M, Kimura S, Terasaki K, Sera K, Narushima T, Araki Y. Accumulation of element Ti in macrophage-like RAW264 cells cultured in medium with 1 ppm Ti and effects on cell viability, SOD production and TNF-alpha secretion. Dent Mater J 2007 25:726-32 PubMed ID: 17338307

8850 Yamaguchi N, Kukita T, Li YJ, Martinez Argueta JG, Saito T, Hanazawa S, Yamashita Y. Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans. FEMS Immunol. Med. Microbiol. 2007 49:28-34 PubMed ID: 17094790

4889 Takayoshi Suganami, Kanami Tanimoto-Koyama, Junko Nishida, Michiko Itoh, Xunmei Yuan, Shinji Mizuarai, Hidehito Kotani, Shoji Yamaoka, Kensuke Miyake, Seiichiro Aoe, Yasutomi Kamei and Yoshihiro Ogawa Role of the Toll-like Receptor 4/NF-κB Pathway in Saturated Fatty Acid−Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages Arterioscler Thromb Vasc Biol 2007 27:84-91 PubMed ID: 17082484

7269 Takarada T, Hinoi E, Kambe Y, Sahara K, Kurokawa S, Takahata Y, Yoneda Y. Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative cytotoxicity of ascorbic acid. Eur J Pharmacol 2007 575(1-3):1-11 PubMed ID: 17698058

7349 Ito M, Haito S, Furumoto M, Uehata Y, Sakurai A, Segawa H, Tatsumi S, Kuwahata M, Miyamoto K. Unique uptake and efflux systems of inorganic phosphate in osteoclast-like cells. Am J Physiol Cell Physiol 2007 292(1):C526-34 PubMed ID: 16971494

7387 Murakami Y, Hirata A, Ito S, Shoji M, Tanaka S, Yasui T, Machino M, Fujisawa S. Re-evaluation of cyclooxygenase-2-inhibiting activity of vanillin and guaiacol in macrophages stimulated with lipopolysaccharide. Anticancer Res 2007 27(2):801-7 PubMed ID: 17465205

10072 Yoshinari Uehara 1, Shin-ichiro Miura, Arnold von Eckardstein, Satomi Abe, Akihiro Fujii, Yoshino Matsuo, Stephan Rust, Stefan Lorkowski, Gerd Assmann, Tatsuo Yamada, Keijiro Saku Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element Atherosclerosis 2007 191(1):11-21 PubMed ID: 16730733

12814 Uto T, Fujii M, Hou DX. Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-gamma and 12-O-tetradecanoylphorbol-13-acetate Oncol Rep 2007 17(1):233-8 PubMed ID: 17143503

15374 Natalie Ohashi, Miho Nakamura, Akiko Nagai, Yumi Tanaka, Yasutaka Sekijima, Kimihiro Yamashita Comparison of Hydroxyapatite with Carbonate Apatite in Osteoclastic Cell Resorptive Activity Key Engineering Materials 2007 361-363:1039-1042

15378 Yuki Kaneshita, Seiji Goda, Tatsuo Kawamoto The effect of matrix metalloproteinase-9 on the differentiation into osteoclast cells on RAW264 cells Orthodontic Waves 2007 66:122-128

15379 Kentaro Harutsugu, Kyoko Watanabe, Michiharu Daito The role of anti immune response on adenosine stimulated macrophages Pediatric Dental Journal 2007 1:40-46

15642 Junji TANAKA, Shao-Jie SHAN, Naoki KASAJIMA, Hiroshi SHIMODA Suppressive Effect of Defatted Kiwi Fruit Seed Extract on Acute Inflammation and Skin Pigmentation Food Science and Technology Research 2007 13:310-314

8917 Soji Fukumoto, Paramasari Dirgahayu, Kozue Nunomura, Haruyo Matsuura andKazumitsu Hirai Suppression of LPS-induced Cyclooxygenase-2 (cox-2) Gene Expression in Mouse Macrophages by Excretory/Secretory Products of Spirometra erinaceieuropaei Plerocercoids Yonago Acta Med. 2006 49:39-47

6489 Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A. TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells. Arthritis Res Ther 2006 8(5):R146 PubMed ID: 16945157

6976 Nagai N, Anzawa T, Satoh Y, Suzuki T, Tajima K, Munekata M. Activities of MC3T3-E1 cells cultured on gamma-irradiated salmon atelocollagen scaffold. J Biosci Bioeng 2006 101(6):511-4 PubMed ID: 16935254

7020 Murakami Y, Shoji M, Ogiwara T, Tanaka S, Yokoe I, Fujisawa S. Preventive effect of ortho dimer of butylated hydroxyanisole on activator protein-1 activation and cyclooxygenase-2 expression in macrophages stimulated by fimbriae of Porphyromonas gingivalis, an oral anaerobe. Anticancer Res 2006 26(4B):2915-20 PubMed ID: 16886613

7039 Funaba M, Nakaya K, Ikeda T, Murakami M, Tsuchida K, Sugino H. Requirement of Smad3 for mast cell growth. Cell Immunol 2006 240(1):47-52 PubMed ID: 16839529

11012 Mohammad Samiul Alam, Mohammad Hasan Zaki, Jun Yoshitake, Teruo Akuta, Takayuki Ezaki, Takaaki Akaike Involvement of Salmonella enterica serovar Typhi RpoS in resistance to NO-mediated host defense against serovar Typhi infection Microb Pathog 2006 40(3):116-25 PubMed ID: 16448800

13660 Kimura Y, Sumiyoshi M, Suzuki T, Sakanaka M. Antitumor and antimetastatic activity of a novel water-soluble low molecular weight beta-1, 3-D-glucan (branch beta-1,6) isolated from Aureobasidium pullulans 1A1 strain black yeast Anticancer Res 2006 26(6B):4131-41 PubMed ID: 17201124

13729 Imamura T, Bando N, Yamanishi R. Beta-carotene modulates the immunological function of RAW264, a murine macrophage cell line, by enhancing the level of intracellular glutathione Biosci Biotechnol Biochem 2006 70(9):2112-20. PubMed ID: 16960387

15371 Suzuki N, Yoshimura Y, Deyama Y, Suzuki K, Kitagawa Y. Mechanical stress directly suppresses osteoclast differentiation in RAW264.7 cells Int J Mol Med 2006 21(3):291-6 PubMed ID: 18288375

15381 KYOKO WATANABE, SHINYA SHIRASU, KIYOSHI DAITO, MASAHARU MOTOYAMA, YOSHITOMO OGAWA, KOJI NAKAI, KIYOSHI OHURA, MICHIHARU DAITO Differentiation of the expression of A2a adenosine receptor in macrophage cell lines RAW264 ORAL THERAPEUTICS AND PHARMACOLOGY 2006 25:8-16

15382 Hida S, Nagi-Miura N, Adachi Y, Ohno N. Beta-glucan derived from zymosan acts as an adjuvant for collagen-induced arthritis Microbiol Immunol 2006 50(6):453-61 PubMed ID: 16785717

15383 Casolaro M, Bottari S, Ito Y. Vinyl polymers based on L-histidine residues. Part 2. Swelling and electric behavior of smart poly(ampholyte) hydrogels for biomedical applications Biomacromolecules 2006 ;7(5):1439-48 PubMed ID: 16677025

15384 Funaba M, Murakami M, Ikeda T, Ogawa K, Tsuchida K, Sugino H. Identification of tocopherol-associated protein as an activin/TGF-beta-inducible gene in mast cells Biochim Biophys Acta 2006 1763(8):900-6 PubMed ID: 16872693

3160 Wei, Ping, Taniguchi, Susumu, Sakai, Yoshiyuki, Imamura, Minako, Inoguchi, Toyoshi, Nawata, Hajime, Oda, Shinya, Nakabeppu, Yusaku, Nishimura, Junji, Ikuyama, Shoichiro Expression of adipose differentiation-related protein (ADRP) is conjointly regulated by PU.1 and AP-1 in macrophages. J Biochem 2005 138:399-412 PubMed ID: 16272134

2903 Shimomura-Shimizu M, Sugiyama K, Muroi M, Tanamoto K Alachlor and carbaryl suppress lipopolysaccharide-induced iNOS expression by differentially inhibiting NF-kappaB activation. Biochem Biophys Res Commun 2005 332:793-9 PubMed ID: 15907790

2922 Musikacharoen, Tipayaratn, Oguma, Asako, Yoshikai, Yasunobu, Chiba, Norika, Masuda, Akio, Matsuguchi, Tetsuya Interleukin-15 induces IL-12 receptor beta1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling. Blood 2005 105:711-20 PubMed ID: 15345588

3365 Ito, Mikiko, Matsuka, Naoko, Izuka, Michiyo, Haito, Sakiko, Sakai, Yuko, Nakamura, Rie, Segawa, Hiroko, Kuwahata, Masashi, Yamamoto, Hironori, Pike, Wesley J, Miyamoto, Ken-ichi Characterization of inorganic phosphate transport in osteoclast-like cells. Am J Physiol Cell Physiol 2005 288:C921-31 PubMed ID: 15601753

3392 Aki, Daisuke, Mashima, Ryuichi, Saeki, Kazuko, Minoda, Yasumasa, Yamauchi, Moriyasu, Yoshimura, Akihiko Modulation of TLR signalling by the C-terminal Src kinase (Csk) in macrophages. Genes Cells 2005 10:357-68 PubMed ID: 15773898

3210 Hou, De-Xing, Yanagita, Takashi, Uto, Takuhiro, Masuzaki, Satoko, Fujii, Makoto Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved. Biochem Pharmacol 2005 70:417-25 PubMed ID: 15963474

3190 Hassan, Ferdaus, Islam, Shamima, Mu, Mya Mya, Ito, Hiroyasu, Koide, Naoki, Mori, Isamu, Yoshida, Tomoaki, Yokochi, Takashi Lipopolysaccharide prevents doxorubicin-induced apoptosis in RAW 264.7 macrophage cells by inhibiting p53 activation. Mol Cancer Res 2005 3:373-9 PubMed ID: 16046548

3098 Suganami, Takayoshi, Nishida, Junko, Ogawa, Yoshihiro A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler Thromb Vasc Biol 2005 25:2062-2068 PubMed ID: 16123319

3209 Uto, Takuhiro, Fujii, Makoto, Hou, De-Xing 6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages. Biochem Pharmacol 2005 70:1211-21 PubMed ID: 16139249

9122 Kobayashi Y, Mizoguchi T, Take I, Kurihara S, Udagawa N, Takahashi N. Prostaglandin E2 enhances osteoclastic differentiation of precursor cells through protein kinase A-dependent phosphorylation of TAK1. J. Biol. Chem. 2005 280:11395-403 PubMed ID: 15647289

2919 Abe T, Hemmi H, Miyamoto H, Moriishi K, Tamura S, Takaku H, Akira S, Matsuura Y. Involvement of the Toll-like receptor 9 signaling pathway in the induction of innate immunity by baculovirus. J Virol 2005 79(5):2847-58 PubMed ID: 15709004

5921 Uto T, Fujii M, Hou DX. Inhibition of lipopolysaccharide-induced cyclooxygenase-2 transcription by 6-(methylsulfinyl) hexyl isothiocyanate, a chemopreventive compound from Wasabia japonica (Miq.) Matsumura, in mouse macrophages. Biochem Pharmacol 2005 70(12):1772-84 PubMed ID: 16256955

6868 Hirata A, Murakami Y, Atsumi T, Shoji M, Ogiwara T, Shibuya K, Ito S, Yokoe I, Fujisawa S. Ferulic acid dimer inhibits lipopolysaccharide-stimulated cyclooxygenase-2 expression in macrophages. In Vivo 2005 19(5):849-53 PubMed ID: 16097437

6869 Hirata A, Murakami Y, Shoji M, Kadoma Y, Fujisawa S. Kinetics of radical-scavenging activity of hesperetin and hesperidin and their inhibitory activity on COX-2 expression. Anticancer Res 2005 25(5):3367-74 PubMed ID: 16101151

6873 Murakami Y, Ito S, Atsumi T, Fujisawa S. Theoretical prediction of the relationship between phenol function and COX-2/AP-1 inhibition for ferulic acid-related compounds. In Vivo 2005 19(6):1039-43 PubMed ID: 16277019

6874 Okada N, Hirata A, Murakami Y, Shoji M, Sakagami H, Fujisawa S. Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression by eugenol-related compounds. Anticancer Res 2005 25(5):3263-9 PubMed ID: 16101137

12262 Tomohiro Konno, Hirokazu Hasuda, Kazuhiko Ishihara, Yoshihiro Ito Photo-immobilization of a phospholipid polymer for surface modification Biomaterials 2005 26(12):1381-8 PubMed ID: 15482825

12263 Hirokazu Hasuda , Oh Hyeong Kwon, Inn-Kyu Kang, Yoshihiro Ito Synthesis of photoreactive pullulan for surface modification Biomaterials 2005 26(15):2401-6 PubMed ID: 15585243

15385 Kyoko Watanabe Differentiation by LPS and IFN-γ of expression of adenosine receptors in macrophage cell lines RAW264 and J774 Pediatric Dental Journal 2005 15:43-51

15386 Koji Tatebayashi, Eiko Matsui, Hideo Kaneko, Toshiyuki Fukao, Kimiko Kasahara, Naomi Kondo IL-12B Promoter Polymorphism Associated with Asthma and IL-12B Transcriptional Activity Allergology International 2005 54:451-459

15387 Kurozumi R, Takahashi M, Kojima S. Involvement of mitochondrial peroxynitrite in nitric oxide-induced glutathione synthesis Biol Pharm Bull 2005 28(5):779-85 PubMed ID: 15863878

15388 Mario Casolaro, Eugenio Paccagnini, Raniero Mendichi, Yoshihiro Ito Stimuli-Responsive Polymers Based on l-Phenylalanine Residues: Protonation Thermodynamics of Free Polymers and Cross-Linked Hydrogels Macromolecules 2005 38:2460-2468

15389 Hatao F, Hiki N, Mimura Y, Ogawa T, Kojima J, Mafune K, Hawkins LD, Muroi M, Tanamoto K, Kaminishi M. The induction of super-resistance using synthetic lipopolysaccharide receptor agonist rescues fatal endotoxemia in rats without excessive immunosuppression Shock 2005 23(4):365-70 PubMed ID: 15803061

2890 Ito T, Morimatsu M, Oonuma T, Shiina T, Kitamura H, Syuto B Transcriptional regulation of the MAIL gene in LPS-stimulated RAW264 mouse macrophages. Gene 2004 342:137-43 PubMed ID: 15527973

2904 Itoh CE, Kizaki T, Hitomi Y, Hanawa T, Kamiya S, Ookawara T, Suzuki K, Izawa T, Saitoh D, Haga S, Ohno H Down-regulation of beta2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation. Biochem Biophys Res Commun 2004 322:979-84 PubMed ID: 15336560

3200 Suzuki, Shogo, Nishimaki-Mogami, Tomoko, Tamehiro, Norimasa, Inoue, Kazuhide, Arakawa, Reijiro, Abe-Dohmae, Sumiko, Tanaka, Arowu R, Ueda, Kazumitsu, Yokoyama, Shinji Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism. Arterioscler Thromb Vasc Biol 2004 24:519-25 PubMed ID: 14726413

3229 Okuhira, Kei-ichiro, Tsujita, Maki, Yamauchi, Yoshio, Abe-Dohmae, Sumiko, Kato, Koichi, Handa, Tetsurou, Yokoyama, Shinji Potential involvement of dissociated apoA-I in the ABCA1-dependent cellular lipid release by HDL. J Lipid Res 2004 45:645-52 PubMed ID: 14729855

3193 Ban, Hyun Seung, Suzuki, Katsuya, Lim, Soon Sung, Jung, Sang Hoon, Lee, Sanghyun, Ji, Jun, Lee, Hye Seung, Lee, Yeon Sil, Shin, Kuk Hyun, Ohuchi, Kazuo Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by 2'-hydroxychalcone derivatives in RAW 264.7 cells. Biochem Pharmacol 2004 67:1549-57 PubMed ID: 15041472

3212 Kato, Sawako, Yuzawa, Yukio, Tsuboi, Naotake, Maruyama, Shoichi, Morita, Yoshiki, Matsuguchi, Tetsuya, Matsuo, Seiichi Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4. J Am Soc Nephrol 2004 15:1289-99 PubMed ID: 15100369

2688 Takahashi, Tetsuyuki, Takasuka, Nobuo, Iigo, Masaaki, Baba, Masaki, Nishino, Hoyoku, Tsuda, Hiroyuki, Okuyama, Toru Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development. Cancer Sci 2004 95:448-53 PubMed ID: 15132774

3220 Adachi, Yoshiyuki, Ishii, Takashi, Ikeda, Yoshihiko, Hoshino, Akiyoshi, Tamura, Hiroshi, Aketagawa, Jun, Tanaka, Shigenori, Ohno, Naohito Characterization of beta-glucan recognition site on C-type lectin, dectin 1. Infect Immun 2004 72:4159-71 PubMed ID: 15213161

3364 Hatao, Fumihiko, Muroi, Masashi, Hiki, Naoki, Ogawa, Toshihisa, Mimura, Yoshikazu, Kaminishi, Michio, Tanamoto, Ken-ichi Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein. J Leukoc Biol 2004 76:904-8 PubMed ID: 15258191

3197 Matsumoto, Masahito, Kogawa, Masakazu, Wada, Seiki, Takayanagi, Hiroshi, Tsujimoto, Masafumi, Katayama, Shigehiro, Hisatake, Koji, Nogi, Yasuhisa Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1. J Biol Chem 2004 279:45969-79 PubMed ID: 15304486

2865 Ikeda, Fumiyo, Nishimura, Riko, Matsubara, Takuma, Tanaka, Sakae, Inoue, Jun-ichiro, Reddy, Sakamuri V, Hata, Kenji, Yamashita, Kenji, Hiraga, Toru, Watanabe, Toshiyuki, Kukita, Toshio, Yoshioka, Katsuji, Rao, Anjana, Yoneda, Toshiyuki Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. J Clin Invest 2004 114:475-84 PubMed ID: 15314684

3135 Kimura T. et al. Novel PVA-DNA nanoparticles prepared by ultra high pressure technology for gene delivery. Materials Science and Engineering C 2004 24:797-801

6477 Ogasawara T, Katagiri M, Yamamoto A, Hoshi K, Takato T, Nakamura K, Tanaka S, Okayama H, Kawaguchi H. Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6). J Bone Miner Res 2004 19(7):1128-36 PubMed ID: 15176996

6737 Naruse M, Otsuka E, Naruse M, Ishihara Y, Miyagawa-Tomita S, Hagiwara H. Inhibition of osteoclast formation by 3-methylcholanthrene, a ligand for arylhydrocarbon receptor: suppression of osteoclast differentiation factor in osteogenic cells. Biochem Pharmacol 2004 67(1):119-27 PubMed ID: 14667934

13881 Sato A, Keng VW, Yamamoto T, Kasamatsu S, Ban T, Tanaka H, Satoh S, Yamada K, Noguchi T. Identification and characterization of the hematopoietic cell-specific enhancer-like element of the mouse hex gene J Biochem 2004 135(2):259-68 PubMed ID: 15047729

14419 Nakamichi K, Inoue S, Takasaki T, Morimoto K, Kurane I. Rabies virus stimulates nitric oxide production and CXC chemokine ligand 10 expression in macrophages through activation of extracellular signal-regulated kinases 1 and 2 J Virol 2004 78(17):9376-88 PubMed ID: 15308732

6705 Murakami Y, Shoji M, Hanazawa S, Tanaka S, Fujisawa S. Preventive effect of bis-eugenol, a eugenol ortho dimer, on lipopolysaccharide-stimulated nuclear factor kappa B activation and inflammatory cytokine expression in macrophages. Biochem Pharmacol 2003 66(6):1061-6 PubMed ID: 12963494

15298 Kyoko Watanabe, Yasutaka Azuma, Shinya Shirasu, Michiharu Daito, Kiyoshi Ohura Alteration of the Expression of A 2 a Adenosine Receptor and Toll-like Receptor 4 in Macrophage Cell Lines. Japanese Journal of Oral Biology 2003 45:437-444

2664 Kizaki, Takako, Suzuki, Kenji, Hitomi, Yoshiaki, Taniguchi, Naoyuki, Saitoh, Daizoh, Watanabe, Kenji, Onoe, Kazunori, Day, Noorbibi K, Good, Robert A, Ohno, Hideki Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages. Proc Natl Acad Sci U S A 2002 99:9392-7 PubMed ID: 12089332

2654 Muroi, Masashi, Tanamoto, Ken-Ichi The polysaccharide portion plays an indispensable role in Salmonella lipopolysaccharide-induced activation of NF-kappaB through human toll-like receptor 4. Infect Immun 2002 70:6043-7 PubMed ID: 12379680

2521 Kinjyo I, Hanada T, Inagaki-Ohara K, Mori H, Aki D, Ohishi M, Yoshida H, Kubo M, Yoshimura A. SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. Immunity 2002 17(5):583-91 PubMed ID: 12433365

2529 Yamamoto A, Miyazaki T, Kadono Y, Takayanagi H, Miura T, Nishina H, Katada T, Wakabayashi K, Oda H, Nakamura K, Tanaka S. Possible involvement of IkappaB kinase 2 and MKK7 in osteoclastogenesis induced by receptor activator of nuclear factor kappaB ligand. J Bone Miner Res 2002 17(4):612-21 PubMed ID: 11918218

6686 Naraba H, Yokoyama C, Tago N, Murakami M, Kudo I, Fueki M, Oh-Ishi S, Tanabe T. Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1. J Biol Chem 2002 277(32):28601-8 PubMed ID: 12034740

15299 Shibuya A, Wada K, Nakajima A, Saeki M, Katayama K, Mayumi T, Kadowaki T, Niwa H, Kamisaki Y. Nitration of PPARgamma inhibits ligand-dependent translocation into the nucleus in a macrophage-like cell line, RAW 264 FEBS Lett 2002 525(1-3):43-7 PubMed ID: 12163159

15390 Tsuboi N, Yoshikai Y, Matsuo S, Kikuchi T, Iwami K, Nagai Y, Takeuchi O, Akira S, Matsuguchi T. Roles of toll-like receptors in C-C chemokine production by renal tubular epithelial cells J Immunol 2002 169(4):2026-33 PubMed ID: 12165529

15391 Shuji Kojima, Risa Kurozumi, Maiko Tuchiya A New Functional Role of 5,6,7,8-tetrahydrobiopterin (BH4) as an Inhibitor of γ-glutamylcysteine Synthetase (γ-GCS) mRNA Expression pteridines 2002 13:83-88

15392 Risa Kurozumi, Shuji Kojima Low-level Nitric Oxide Blunts Oxidant Injury via Up-regulating Glutathione Synthes. Journal of Health Science 2002 48:140-147

16972 Wakabayashi I, Yasui K, Negoro M. Diverse effects of ethanol on the pathway of inducible prostaglandin E2 production in macrophages Prostaglandins Other Lipid Mediat 2002 67(1):61-74 PubMed ID: 11789898

2504 Haruta I, Kato Y, Hashimoto E, Minjares C, Kennedy S, Uto H, Yamauchi K, Kobayashi M, Yusa S, Muller U, Hayashi N, Miyazaki T Association of AIM, a novel apoptosis inhibitory factor, with hepatitis via supporting macrophage survival and enhancing phagocytotic function of macrophages. J Biol Chem 2001 276:22910-4 PubMed ID: 11294859

2973 Shiina T, Morimatsu M, Kitamura H, Ito T, Kidou S, Matsubara K, Matsuda Y, Saito M, Syuto B Genomic organization, chromosomal localization, and promoter analysis of the mouse Mail gene. Immunogenetics 2001 53:649-55 PubMed ID: 11797098

3777 Arima H, Kihara F, Hirayama F, Uekama K. Enhancement of gene expression by polyamidoamine dendrimer conjugates with alpha-, beta-, and gamma-cyclodextrins. Bioconjug Chem 2001 12(4):476-84 PubMed ID: 11459450

6657 Kikuchi T, Matsuguchi T, Tsuboi N, Mitani A, Tanaka S, Matsuoka M, Yamamoto G, Hishikawa T, Noguchi T, Yoshikai Y. Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. J Immunol 2001 166(5):3574-9 PubMed ID: 11207318

9033 E Noiri, A Nakao, K Uchida, H Tsukahara, M Ohno, T Fujita, S Brodsky, M S Goligorsky Oxidative and Nitrosative Stress in Acute Renal Ischemia Am J Physiol Renal Physiol 2001 281 (5), F948-57 PubMed ID: 11592952

15393 Yokohari K, Yamashita Y, Okada S, Ohya K, Oda S, Hatano M, Mano H, Hirasawa H, Tokuhisa T. Isoform-dependent interaction of BRDG1 with Tec kinase Biochem Biophys Res Commun 2001 289(2):414-20 PubMed ID: 11716489

15394 Aramaki Y, Takano S, Tsuchiya S. Cationic liposomes induce macrophage apoptosis through mitochondrial pathway Arch Biochem Biophys 2001 392(2):245-50 PubMed ID: 11488598

15395 Takano S, Aramaki Y, Tsuchiya S. Lipoxygenase may be involved in cationic liposome-induced macrophage apoptosis Biochem Biophys Res Commun 2001 288(1):116-20 PubMed ID: 11594761

15396 Matsumoto M, Hisatake K, Nogi Y, Tsujimoto M. Regulation of receptor activator of NF-kappaB ligand-induced tartrate-resistant acid phosphatase gene expression by PU.1-interacting protein/interferon regulatory factor-4. Synergism with microphthalmia transcription factor J Biol Chem 2001 276(35):33086-92 PubMed ID: 11425859

15397 Matsuguchi T, Musikacharoen T, Johnson TR, Kraft AS, Yoshikai Y. A novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines Mol Cell Biol 2001 21(20):6999-7009 PubMed ID: 11564882

15623 Ke X, Terashima M, Nariai Y, Nakashima Y, Nabika T, Tanigawa Y. Nitric oxide regulates actin reorganization through cGMP and Ca(2+)/calmodulin in RAW 264.7 cells Biochim Biophys Acta 2001 1539(1-2):101-13 PubMed ID: 11389972

16918 Van Dien M, Takahashi K, Mu MM, Koide N, Sugiyama T, Mori I, Yoshida T, Yokochi T. Protective effect of wogonin on endotoxin-induced lethal shock in D-galactosamine-sensitized mice Microbiol Immunol 2001 45(11):751-6 PubMed ID: 11791668

3224 Abe-Dohmae S, Suzuki S, Wada Y, Aburatani H, Vance, D E, Yokoyama S Characterization of apolipoprotein-mediated HDL generation induced by cAMP in a murine macrophage cell line. Biochemistry 2000 39:11092-9 PubMed ID: 10998247

3225 Suzuki S, Abe-Dohmae S, Fukutomi T, Ito S, Itoh M, Yokoyama S Enhancement of the cAMP-induced apolipoprotein-mediated cellular lipid release by calmodulin inhibitors W7 and W5 from RAW 264 mouse macrophage cell line cells. J Cardiovasc Pharmacol 2000 36:609-16 PubMed ID: 11065221

3991 Matsumoto M, Sudo T, Maruyama M, Osada H, Tsujimoto M. Activation of p38 mitogen-activated protein kinase is crucial in osteoclastogenesis induced by tumor necrosis factor. FEBS Lett 2000 486(1):23-8 PubMed ID: 11108836

3994 Iwahashi H, Takeshita A, Hanazawa S. Prostaglandin E2 stimulates AP-1-mediated CD14 expression in mouse macrophages via cyclic AMP-dependent protein kinase A. J Immunol 2000 164(10):5403-8 PubMed ID: 10799905

3531 Matsumoto M, Sudo T, Saito T, Osada H, Tsujimoto M. Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL). J Biol Chem 2000 275(40):31155-61 PubMed ID: 10859303

15403 Hiroyuki Iizuka, Hirofumi Sagara, Shuji Kojima Modulation of LPS-induced Cell Death by 5,6,7,8-Tetrahydrobiopterin pteridines 1999 10:202-206

15405 Keiichiro Yoshida, Michio Ono, Hajime Sawada Lipopolysaccharide-induced vacuoles in macrophages: Their origin is plasma membrane-derived organelles and endoplasmic reticulum, but not lysosomes Journal of Endotoxin Research 1999 5:127-137

2423 Okada S, Zhang H, Hatano M, Tokuhisa T A physiologic role of Bcl-xL induced in activated macrophages. J Immunol 1998 160:2590-6 PubMed ID: 9510156

15402 Yoko Ishihara Norihiko Kohyama Atsu CELLULAR BIOLOGICAL EFFECTS AND A SINGLE TRANSTRACHEAL INJECTION TEST IN THREE TYPES OF WHISKER FIBERS Inhalation Toxicology 1998 10:275-291

2366 Yamashita M, Niki H, Yamada M, Mue S, Ohuchi K Induction of nitric oxide synthase by lipopolysaccharide and its inhibition by auranofin in RAW 264.7 cells. Eur J Pharmacol 1997 338:151-8 PubMed ID: 9455997

15398 Ohata T, Fukuda K, Takahashi M, Sugimura T, Wakabayashi K. Suppression of nitric oxide production in lipopolysaccharide-stimulated macrophage cells by omega 3 polyunsaturated fatty acids Jpn J Cancer Res 1997 88(3):234-7 PubMed ID: 9140106

15399 Iwamoto N, Ito K, Kakuchi J, Yoshioka T. Quenching of nitric oxide by an oral carbonaceous adsorbent Jpn J Pharmacol 1997 74(2):213-6 PubMed ID: 9243331

15400 Arima H, Aramaki Y, Tsuchiya S. Contribution of trypsin-sensitive proteins to binding of cationic liposomes to the mouse macrophage-like cell line RAW264.7 J Pharm Sci 1997 86(7):786-90 PubMed ID: 9232517

14430 Yoshimoto T, Kojima K, Funakoshi T, Endo Y, Fujita T, Nariuchi H. Molecular cloning and characterization of murine IL-12 genes J Immunol 1996 156(3):1082-8 PubMed ID: 8557982

15401 K. Takada, N. Ohno, T. Yadomae Physicochemical and biological characterizations of complex formation between lipopolysaccharide and lysozyme Journal of Endotoxin Research 1995 2:255-262

1645 Tanida N, Ohno N, Adachi Y, Matsuura M, Nakano M, Kiso M, Hasegawa A, Yadomae T Modification of Immunopharmacologicaln Activities of Synthetic Monosaccharide Lipid A Analogue, GLA60, by Lysozyme J Biochem 1992 112:616-623 PubMed ID: 1478920