Search
CELL BANK Website

Back Back
Cell No. : Cell Name
RCB0500 : HGC-27  update : 2022/04/05
CommentHuman cell line derived from metastatic lymph node of gastric cancer (undifferentiated carcinoma).
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Kimoto, Tetsuo
Originator Akagi, Tadaatsu
Year of deposit 1990
Animal human < Mammals
Genus Homo
Species sapiens
Race Japanese
Age at sampling adult
Tissue stomach, lymph node meta
Disease name gastric cancer
Metastastatic ability Yes
Metastatsd tissue lymph node
Classification cancer
Year of origin 1973
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_1279
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives MEM + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Virus (HIV) (-)
Isozyme LD, NP
Chromosome mode 67-76(50) : 69(7),70(7),71(12),72(7),73(4),74(4)/
STR(human) OK
Images
deposit info
lot info
Reference information Reference 1
User's Publication 80


To topTop
Reference
1281  Akagi T, Kimoto T  Human cell line (HGC-27) derived from the metastatic lymph node of gastric cancer.  Acta Med Okayama  1976  30:215-9  PubMed ID: 136873  

To topTop
User's Publication
20459  Kato S, Shiozaki A, Kudou M, Shimizu H, Kosuga T, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.  TRPV2 Promotes Cell Migration and Invasion in Gastric Cancer via the Transforming Growth Factor-β Signaling Pathway.  Ann Surg Oncol  2022    PubMed ID: 34855064   DOI: 10.1245/s10434-021-11132-5
20622  Takaki W, Konishi H, Matsubara D, Shoda K, Arita T, Kataoka S, Shibamoto J, Furuke H, Takabatake K, Shimizu H, Komatsu S, Shiozaki A, Kubota T, Okamoto K, Otsuji E.  Role of Extracellular High-Mobility Group Box-1 as a Therapeutic Target of Gastric Cancer.  Int J Mol Sci  2022  23(6)  PubMed ID: 35328684   DOI: 10.3390/ijms23063264
20633  Chen Y, Jiang L, Xia L, Zhang G, Chen L.  ThPOK inhibits the immune escape of gastric cancer cells by inducing STPG1 to inactivate the ERK pathway.  BMC Immunol  2022  23(1):16  PubMed ID: 35379170   DOI: 10.1186/s12865-022-00485-5
20661  Inoue H, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.  Functions and Clinical Significance of CACNA2D1 in Gastric Cancer.  Ann Surg Oncol  2022    PubMed ID: 35445337   DOI: 10.1245/s10434-022-11752-5
16737  Yusuke Takizawa, Junya Oguri, Masaya Uno, Ami Onsui, Atsushi Ishimura, Takuro Kurita, Takanori Nakajima  Effects of A GLP‑1 Receptor Agonist on Gastrointestinal Epithelial Cells  Scholars Academic Journal of Pharmacy  2022  11:60-66    DOI: 10.36347/sajp.2022.v11i04.002
17107  Liu B, Katoh H, Komura D, Yamamoto A, Ochi M, Onoyama T, Abe H, Ushiku T, Seto Y, Suo J, Ishikawa S.  Functional genomics screening identifies aspartyl-tRNA synthetase as a novel prognostic marker and a therapeutic target for gastric cancers  J Pathol  2022  2022 Jun 13  PubMed ID: 35696251   DOI: 10.1002/path.5980
20908  Wang X, Zhang L, Liang Q, Wong CC, Chen H, Gou H, Dong Y, Liu W, Li Z, Ji J, Yu J.  DUSP5P1 promotes gastric cancer metastasis and platinum drug resistance.  Oncogenesis  2022  11(1):66  PubMed ID: 36307394   DOI: 10.1038/s41389-022-00441-3
13323  Nishibeppu K, Komatsu S, Kiuchi J, Kishimoto T, Takashima Y, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E.  TRIM37 contributes to malignant outcomes and CDDP resistance in gastric cancer.  J Cancer  2021    PubMed ID: 33391428   DOI: 10.7150/jca.47577
20116  Kurashima K, Shiozaki A, Kudou M, Shimizu H, Arita T, Kosuga T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.  LRRC8A influences the growth of gastric cancer cells via the p53 signaling pathway.  Gastric Cancer  2021    PubMed ID: 33864161   DOI: 10.1007/s10120-021-01187-4
20127  Chen R, Masuo K, Yogo A, Yokoyama S, Sugiyama A, Seno H, Yoshizawa A, Takaishi S.  SNAIL regulates gastric carcinogenesis through CCN3 and NEFL.  Carcinogenesis  2021  42(2):190-201  PubMed ID: 33313663   DOI: 10.1093/carcin/bgaa133
20148  Kubo H, Murayama Y, Ogawa S, Matsumoto T, Yubakami M, Ohashi T, Kubota T, Okamoto K, Kamiya M, Urano Y, Otsuji E.  β-Galactosidase is a target enzyme for detecting peritoneal metastasis of gastric cancer.  Sci Rep  2021  11(1):10664  PubMed ID: 34021168   DOI: 10.1038/s41598-021-88982-2
14345  Katsurahara K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.  ANO9 regulates PD-L2 expression and binding ability to PD-1 in gastric cancer  Cancer Sci  2021  112(3):1026-1037.   PubMed ID: 33404124   DOI: 10.1111/cas.14796
20224  Ogawa S, Kubo H, Murayama Y, Kubota T, Yubakami M, Matsumoto T, Ohashi T, Okamoto K, Kuriki Y, Hanaoka K, Urano Y, Otsuji E.  Matrix metalloprotease-14 is a Target Enzyme for Detecting Peritoneal Metastasis in Gastric Cancer.  Photodiagnosis Photodyn Ther  2021    PubMed ID: 34242818   DOI: 10.1016/j.pdpdt.2021.102420
20358  Zhang J, Wang F, Zhang H, Cao M.  A novel circular RNA circ_HN1/miR-628-5p/Ecto-5'-nucleotidase competing endogenous RNA network regulates gastric cancer development.  Bioengineered  2021    PubMed ID: 34637682   DOI: 10.1080/21655979.2021.1989259
20415  Ikari N, Serizawa A, Tanji E, Yamamoto M, Furukawa T.  Analysis of RHOA mutations and their significance in the proliferation and transcriptome of digestive tract cancer cells.  Oncol Lett  2021  22(4):735  PubMed ID: 34466148   DOI: 10.3892/ol.2021.12996
16126  Nakamura K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.  The expression of the alpha1 subunit of Na +/K +-ATPase is related to tumor development and clinical outcomes in gastric cancer  Gastric Cancer  2021  24(6):1278-1292  PubMed ID: 34251542   DOI: 10.1007/s10120-021-01212-6
9737  Tomohiro Kohmoto, Kiyoshi Masuda, Katsutoshi Shoda, Rizu Takahashi, Sae Ujiro, Shoichiro Tange, Daisuke Ichikawa, Eigo Otsuji, Issei Imoto  Claudin-6 Is a Single Prognostic Marker and Functions as a Tumor-Promoting Gene in a Subgroup of Intestinal Type Gastric Cancer  Gastric Cancer  2020  23(3):403-417  PubMed ID: 31654186   DOI: 10.1007/s10120-019-01014-x
12060  Nishibeppu K, Komatsu S, Imamura T, Kiuchi J, Kishimoto T, Arita T, Kosuga T, Konishi H, Kubota T, Shiozaki A, Fujiwara H, Okamoto K, Otsuji E.  Plasma microRNA profiles: identification of miR-1229-3p as a novel chemoresistant and prognostic biomarker in gastric cancer.  Sci Rep  2020    PubMed ID: 32081926   DOI: 10.1038/s41598-020-59939-8
13454  Wataru Matsunaga, Misa Ichikawa, Takahiro Ishikawa, Akinobu Gotoh  Lentiviral vector-mediated transfection of human cancer cell lines with tumor suppressor genes inhibits proliferation in vitro  Personalized Medicine Universe  2020      DOI: 10.46459/pmu.2020001
14804  Xing M, Ooi WF, Tan J, Qamra A, Lee PH, Li Z, Xu C, Padmanabhan N, Lim JQ, Guo YA, Yao X, Amit M, Ng LM, Sheng T, Wang J, Huang KK, Anene-Nzelu CG, Ho SWT, Ray M, Ma L, Fazzi G, Lim KJ, Wijaya GC, Zhang S, Nandi T, Yan T, Chang MM, Das K, Isa ZFA, Wu J, Poon PSY, Lam YN, Lin JS, Tay ST, Lee MH, Tan ALK, Ong X, White K, Rozen SG, Beer M, Foo RSY, Grabsch HI, Skanderup AJ, Li S, Teh BT, Tan P.  Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer  J Clin Invest  2020  130(6):3005-3020  PubMed ID: 32364535   DOI: 10.1172/JCI126726
11202  Shiozaki A, Ariyoshi Y, Iitaka D, Kosuga T, Shimizu H, Kudou M, Konishi T, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Marunaka Y, Ichikawa D, Otsuji E.  Functional analysis and clinical significance of sodium iodide symporter expression in gastric cancer.  Gastric Cancer  2019    PubMed ID: 30191346   DOI: 10.1007/s10120-018-0874-2
11511  Behan FM, Iorio F, Picco G, Gonçalves E, Beaver CM, Migliardi G, Santos R, Rao Y, Sassi F, Pinnelli M, Ansari R, Harper S, Jackson DA, McRae R, Pooley R, Wilkinson P, van der Meer D, Dow D, Buser-Doepner C, Bertotti A, Trusolino L, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ.  Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.  Nature  2019    PubMed ID: 30971826   DOI: 10.1038/s41586-019-1103-9
9810  Junko Shibato, Fumiko Takenoya, Takahiro Hirabayashi, Ai Kimura, Yusuke Iwasaki, Yoko Toyoda, Motohide Hori, Shigeru Tamogami, Randeep Rakwal, Seiji Shioda  Towards Identification of Bioactive Compounds in Cold Vacuum Extracted Double Cherry Blossom (Gosen-Sakura) Leaves  Plant Signal Behav  2019  14(10):e1644594  PubMed ID: 31342859   DOI: 10.1080/15592324.2019.1644594
12282  Taslima T Lina, Jazmin Gonzalez, Irina V Pinchuk, Ellen J Beswick, Victor E Reyes  Helicobacter pylori elicits B7H3 expression on gastric epithelial cells: Implications in local T cell regulation and subset development during infection  Clin Oncol Res  2019  2(5)  PubMed ID: 31998864   DOI: 10.31487/j.cor.2019.05.05
12448  Zhang B, Zhang X, Jin M, Hu L, Zang M, Qiu W, Wang S, Liu B, Liu S, Guo D.  CagA increases DNA methylation and decreases PTEN expression in human gastric cancer  Mol Med Rep  2019  19(1):309-319  PubMed ID: 30431097   DOI: 10.3892/mmr.2018.9654
10725  Nakamura A, Matsunaga W, Gotoh A.  Autophagy Induced by Naftopidil Inhibits Apoptosis of Human Gastric Cancer Cells.  Anticancer Res.  2018  38:803-809  PubMed ID: 29374705   DOI: 10.21873/anticanres.12287
4190  Kurata A, Yamada M, Ohno SI, Inoue S, Hashimoto H, Fujita K, Takanashi M, Kuroda M.  Expression level of microRNA-200c is associated with cell morphology in vitro and histological differentiation through regulation of ZEB1/2 and E-cadherin in gastric carcinoma.  Oncol. Rep.  2018    PubMed ID: 29138864   DOI: 10.3892/or.2017.6093
4313  Kiuchi J, Komatsu S, Imamura T, Nishibeppu K, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Ichikawa D, Tsuda H, Otsuji E.  Overexpression of YEATS4 contributes to malignant outcomes in gastric carcinoma.  Am J Cancer Res  2018    PubMed ID: 30662802  
14272  Krishnan V, Chong YL, Tan TZ, Kulkarni M, Bin Rahmat MB, Tay LS, Sankar H, Jokhun DS, Ganesan A, Chuang LSH, Voon DC, Shivashankar GV, Thiery JP, Ito Y.  TGFβ Promotes Genomic Instability after Loss of RUNX3  Cancer Res  2018  78(1):88-102  PubMed ID: 29074538   DOI: 10.1158/0008-5472.CAN-17-1178
14733  Imamura T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Ohashi T, Kiuchi J, Nishibeppu K, Kosuga T, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E.  Overexpression of ZRF1 is related to tumor malignant potential and a poor outcome of gastric carcinoma  Carcinogenesis  2018  39(2):263-271  PubMed ID: 29228320   DOI: 10.1093/carcin/bgx139
9978  Kneissl J, Hartmann A, Pfarr N, Erlmeier F, Lorber T, Keller S, Zwingenberger G, Weichert W, Luber B.  Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines.  J. Cancer Res. Clin. Oncol.  2017  143:573-600  PubMed ID: 27933395   DOI: 10.1007/s00432-016-2308-z
10112  Asano M, Sakaguchi M, Tanaka S, Kashimura K, Mitani T, Kawase M, Matsumura H, Yamaguchi T, Fujita Y, Tabuse K.  Effects of Normothermic Conditioned Microwave Irradiation on Cultured Cells Using an Irradiation System with Semiconductor Oscillator and Thermo-regulatory Applicator.  Sci Rep  2017  7:41244  PubMed ID: 28145466   DOI: 10.1038/srep41244
10652  Lin Z, Lai S, He X, Zhuo W, Wang L, Si J, Chen S.  Decreased long non-coding RNA MTM contributes to gastric cancer cell migration and invasion via modulating MT1F.  Oncotarget  2017  8:97371-97383  PubMed ID: 29228617   DOI: 10.18632/oncotarget.22126
5804  Authors: Takashi Okuda Tomohiko Taki Kazuhiro Nishida Yoshiaki Chinen Hisao Nagoshi Chouhei Sakakura Masafumi Taniwaki  Molecular heterogeneity in the novel fusion gene APIP-FGFR2: Diversity of genomic breakpoints in gastric cancer with high-level amplifications at 11p13 and 10q26  Oncology Letters  2017  13(1):215-221  PubMed ID: 28123544   DOI: 10.3892/ol.2016.5386
14271  Muguruma N, Okamoto K, Nakagawa T, Sannomiya K, Fujimoto S, Mitsui Y, Kimura T, Miyamoto H, Higashijima J, Shimada M, Horino Y, Matsumoto S, Hanaoka K, Nagano T, Shibutani M, Takayama T.  Molecular imaging of aberrant crypt foci in the human colon targeting glutathione S-transferase P1-1  Sci Rep  2017  7(1):6536  PubMed ID: 28747791   DOI: 10.1038/s41598-017-06857-x
14619  Kosuga T, Shiozaki A, Kudou M, Yamazato Y, Ichikawa D, Komatsu S, Konishi H, Okamoto K, Shoda K, Arita T, Morimura R, Murayama Y, Kuriu Y, Ikoma H, Nakanishi M, Fujiwara H, Marunaka Y, Otsuji E.  Blockade of potassium ion transports enhances hypotonicity-induced cytocidal effects in gastric cancer  Oncotarget  2017  8(60):101394-101405  PubMed ID: 29254173   DOI: 10.18632/oncotarget.20736
14744  Ohashi T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Imamura T, Kiuchi J, Kosuga T, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E.  Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcinoma  Br J Cancer  2017  116(2):218-226  PubMed ID: 27898655   DOI: 10.1038/bjc.2016.394
5811  Maejima R et al  Enhanced expression of semaphorin 3E is involved in the gastric cancer development.  Int J Oncol  2016  49(3):887-94  PubMed ID: 27572291   DOI: 10.3892/ijo.2016.3593
5812  Hirashita Y et al  Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells.  Cancer Sci  2016  107(12):1919-1928  PubMed ID: 27699948   DOI: 10.1111/cas.13094
14170  Koichiro Hayashi, Wataru Sakamoto, Toshinobu Yogo  Smart Ferrofluid with Quick Gel Transformation in Tumors for MRI-Guided Local Magnetic Thermochemotherapy  Advanced Functional Materials  2016  26:1708-1718    DOI: 10.1002/adfm.201504215
7458  Zhou J, Yong WP, Yap CS, Vijayaraghavan A, Sinha RA, Singh BK, Xiu S, Manesh S, Ngo A, Lim A, Ang C, Xie C, Wong FY, Lin SJ, Wan WK, Tan IB, Flotow H, Tan P, Lim KH, Yen PM, Goh LK.  An integrative approach identified genes associated with drug response in gastric cancer.  Carcinogenesis  2015  36:441-51  PubMed ID: 25742747   DOI: 10.1093/carcin/bgv014
14961  Angiopoietin-like protein 2 is a potential biomarker for gastric cancer  Angiopoietin-like protein 2 is a potential biomarker for gastric cancer  Molecular Medicine Reports  2015  11:2653-2658    DOI: 10.3892/mmr.2014.3040
15159  Honda S, Loher P, Shigematsu M, Palazzo JP, Suzuki R, Imoto I, Rigoutsos I, Kirino Y.  Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers  Proc Natl Acad Sci U S A  2015  112(29):E3816-25  PubMed ID: 26124144   DOI: 10.1073/pnas.1510077112
15244  Lina TT, Alzahrani S, House J, Yamaoka Y, Sharpe AH, Rampy BA, Pinchuk IV, Reyes VE.  Helicobacter pylori cag pathogenicity island's role in B7-H1 induction and immune evasion  PLoS One  2015  10(3):e0121841  PubMed ID: 25807464   DOI: 10.1371/journal.pone.0121841
5833  Sato M, Muguruma N, Nakagawa T, Okamoto K, Kimura T, Kitamura S, Yano H, Sannomiya K, Goji T, Miyamoto H, Okahisa T, Mikasa H, Wada S, Iwata M, Takayama T.  High antitumor activity of pladienolide B and its derivative in gastric cancer.  Cancer Sci  2014  105(1):110-6  PubMed ID: 24635824   DOI: 10.1111/cas.12317
6335  Matsumoto H, Tsuchiya T, Yoshiura K, Hayashi T, Hidaka S, Nanashima A, Nagayasu T.  ABCC11/MRP8 Expression in the Gastrointestinal Tract and a Novel Role for Pepsinogen Secretion.  Acta Histochem Cytochem  2014  47(3):85-94  PubMed ID: 25320405   DOI: 10.1267/ahc.13040
17146  Fawzy A. Attaby, Azza M. Abdel-Fattah, Labeeb M. Shaif, Mohamed M. Elsayed  Synthesis, Reactions, Characterization and Biological Evaluation of 2,3′-Bipyridine Derivatives (III)  Journal of Heterocyclic Chemistry  2014  51:927-936    DOI: 10.1002/jhet.1521
5845  Konno-Shimizu M1, Yamamichi N, Inada K, Kageyama-Yahara N, Shiogama K, Takahashi Y, Asada-Hirayama I, Yamamichi-Nishina M, Nakayama C, Ono S, Kodashima S, Fujishiro M, Tsutsumi Y, Ichinose M, Koike K.  Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.  PLoS One  2013  8(2):e56766  PubMed ID: 23451082   DOI: 10.1371/journal.pone.0056766
14697  Lina TT, Pinchuk IV, House J, Yamaoka Y, Graham DY, Beswick EJ, Reyes VE.  CagA-dependent downregulation of B7-H2 expression on gastric mucosa and inhibition of Th17 responses during Helicobacter pylori infection  J Immunol  2013  191(7):3838-46  PubMed ID: 23997227   DOI: 10.4049/jimmunol.1300524
5850  Miyato H, Tsuno NH, Kitayama J.  Semaphorin 3C is involved in the progression of gastric cancer.  Cancer Sci  2012  103(11):1961-6  PubMed ID: 22924992   DOI: 10.1111/cas.12003
6316  Miyaki Y, Suzuki K, Koizumi K, Kato T, Saito M, Kamiyama H, Maeda T, Shibata K, Shiya N, Konishi F.  Identification of a potent epigenetic biomarker for resistance to camptothecin and poor outcome to irinotecan-based chemotherapy in colon cancer.  Int J Oncol  2012  40(1):217-26  PubMed ID: 21901246   DOI: 10.3892/ijo.2011.1189
5860  Du L, Xiao X, Wang C, Zhang X, Zheng N, Wang L, Zhang X, Li W, Wang S, Dong Z.  Human leukocyte antigen-G is closely associated with tumor immune escape in gastric cancer by increasing local regulatory T cells.  Cancer Sci  2011  102(7):1272-80  PubMed ID: 21466615   DOI: 10.1111/j.1349-7006.2011.01951.x
5871  Galal SA, Hegab KH, Hashem AM, Youssef NS  Synthesis and antitumor activity of novel benzimidazole-5-carboxylic acid derivatives and their transition metal complexes as topoisomerease II inhibitors.  Eur J Med Chem   2010  45(12):5685-91  PubMed ID: 20884089   DOI: 10.1016/j.ejmech.2010.09.023
16973  Riyadh SM, Farghaly TA, Abdallah MA, Abdalla MM, Abd El-Aziz MR.  New pyrazoles incorporating pyrazolylpyrazole moiety: synthesis, anti-HCV and antitumor activity  Eur J Med Chem  2010  45(3):1042-50  PubMed ID: 20022411   DOI: 10.1016/j.ejmech.2009.11.050
8590  Miyato H, Kitayama J, Yamashita H, Souma D, Asakage M, Yamada J, Nagawa H.  Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines.  J. Surg. Res.  2009  155:40-7  PubMed ID: 19394652   DOI: 10.1016/j.jss.2008.06.045
5878  Abdel-Fattah, Azza M.; Elsayed, Mohamed M.  Novel Synthesis, Reactions and anti-Cancer Activities of 4,4'-Benzene-1,4- diylbis(6-phenyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile)  Current Organic Chemistry  2009  13:1751-1757   
5881  Farghaly TA1, Abdalla MM.  Synthesis, tautomerism, and antimicrobial, anti-HCV, anti-SSPE, antioxidant, and antitumor activities of arylazobenzosuberones.  Bioorg Med Chem  2009  17(23):8012-9  PubMed ID: 19864149   DOI: 10.1016/j.bmc.2009.10.012
6410  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Is parainfluenza virus a threatening virus for human cancer cell lines?  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309   DOI: 10.1111/j.1749-0774.2009.00071.x
5888  Kuwabara Y, Yamada T, Yamazaki K, Du WL, Banno K, Aoki D, Sakamoto M.  Establishment of an ovarian metastasis model and possible involvement of E-cadherin down-regulation in the metastasis.  Cancer Sci  2008  99(10):1933-9  PubMed ID: 19016752   DOI: 10.1111/j.1349-7006.2008.00946.x
4524  Takezawa J, Ishimi Y, Yamada K.  Proteasome inhibitors remarkably prevent translesion replication in cancer cells but not normal cells  Cancer Sci  2008  99(5):863-71  PubMed ID: 18294277   DOI: 10.1111/j.1349-7006.2008.00764.x
15084  Maeda O, Kondo M, Fujita T, Usami N, Fukui T, Shimokata K, Ando T, Goto H, Sekido Y.  Enhancement of GLI1-transcriptional activity by beta-catenin in human cancer cells  Oncol Rep  2006  16(1):91-6  PubMed ID: 16786128  
3077  Nakatsu N, Yoshida Y, Yamazaki K, Nakamura T, Dan S, Fukui Y, Yamori T  Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.  Mol Cancer Ther  2005  4:399-412  PubMed ID: 15767549   DOI: 10.1158/1535-7163.MCT-04-0234
13836  Murai Y, Hayashi S, Takahashi H, Tsuneyama K, Takano Y.  Correlation between DNA alterations and p53 and p16 protein expression in cancer cell lines  Pathol Res Pract  2005  201(2):109-15  PubMed ID: 15901131   DOI: 10.1016/j.prp.2005.01.002
2807  Shida D, Kitayama J, Yamaguchi H, Hama K, Aoki J, Arai H, Yamashita H, Mori K, Sako A, Konishi T, Watanabe T, Sakai T, Suzuki R, Ohta H, Takuwa Y, Nagawa H  Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells.  Exp Cell Res  2004  301:168-78  PubMed ID: 15530853   DOI: 10.1016/j.yexcr.2004.08.008
5935  Dan S, Shirakawa M, Mukai Y, Yoshida Y, Yamazaki K, Kawaguchi T, Matsuura M, Nakamura Y, Yamori T.  Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.  Cancer Sci  2003  94(12):1074-82  PubMed ID: 14662023   DOI: 10.1111/j.1349-7006.2003.tb01403.x
5937  Nakamura K, Uenaka T, Nagasu T, Sugumi H, Yamaguchi A, Kotake Y, Okada T, Kamata J, Niijima J, Taniguchi T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K.  A novel carbazole topoisomerase II poison, ER-37328: potent tumoricidal activity against human solid tumors in vitro and in vivo.  Cancer Sci  2003  94(1):119-24  PubMed ID: 12708485   DOI: 10.1111/j.1349-7006.2003.tb01362.x
5942  Nakamura K, Sugumi H, Yamaguchi A, Uenaka T, Kotake Y, Okada T, Kamata J, Niijima J, Nagasu T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K.  Antitumor activity of ER-37328, a novel carbazole topoisomerase II inhibitor.  Mol Cancer Ther  2002  1(3):169-75  PubMed ID: 12467211  
5952  Okada E, Murai Y, Matsui K, Isizawa S, Cheng C, Masuda M, Takano Y.  Survivin expression in tumor cell nuclei is predictive of a favorable prognosis in gastric cancer patients.  Cancer Lett  2001  163(1):109-16  PubMed ID: 11163114   DOI: 10.1016/s0304-3835(00)00677-7
5962  Sato Y, Kashimoto S, MacDonald JR, Nakano K.  In vivo antitumour efficacy of MGI-114 (6-hydroxymethylacylfulvene, HMAF) in various human tumour xenograft models including several lung and gastric tumours.  Eur J Cancer  2001  37(11):1419-28  PubMed ID: 11435075   DOI: 10.1016/s0959-8049(01)00135-6
15590  Kataoka H, Miura Y, Joh T, Seno K, Tada T, Tamaoki T, Nakabayashi H, Kawaguchi M, Asai K, Kato T, Itoh M.  Alpha-fetoprotein producing gastric cancer lacks transcription factor ATBF1  Oncogene  2001  20(7):869-73  PubMed ID: 11314020   DOI: 10.1038/sj.onc.1204160
6409  Hassan S, Kinoshita Y, Kawanami C, Kishi K, Matsushima Y, Ohashi A, Funasaka Y, Okada A, Maekawa T, He-Yao W, Chiba T.  Expression of protooncogene c-kit and its ligand stem cell factor (SCF) in gastric carcinoma cell lines.  Dig Dis Sci  1998  43(1):8-14  PubMed ID: 9508539   DOI: 10.1023/a:1018851415704
2194  Nishizuka S, Tamura G, Maesawa C, Sakata K, Suzuki Y, Iwaya T, Terashima M, Saito K, Satodate R  Analysis of the DPC4 gene in gastric carcinoma  Jpn J Cancer Res  1997  88:335-339  PubMed ID: 9197522   DOI: 10.1111/j.1349-7006.1997.tb00385.x
17234  Ali AM, Mackeen MM, Hamid M, Aun QB, Zauyah Y, Azimahtol HL, Kawazu K.  Cytotoxicity and electron microscopy of cell death induced by goniothalamin  Planta Med  1997  63(1):81-3  PubMed ID: 9063100   DOI: 10.1055/s-2006-957611
17235  Oh KW, Kim HS, Wagner GC.  Ginseng total saponin inhibits the dopaminergic depletions induced by methamphetamine  Planta Med  1997  63(1):80-1  PubMed ID: 9063099   DOI: 10.1055/s-2006-957610
2062  Wang, D S, Ueno Y, Oyamada H, Kojima S  Accumulation of NCC-CO-411 monoclonal antibody in human colorectal adenocarcinoma through binding of the released carcinoembryonic antigen in nude mice.  Biol Pharm Bull  1996  19:915-21  PubMed ID: 8839961   DOI: 10.1248/bpb.19.915
2177  Tamura G, Sakata K, Nishizuka S, Maesawa C, Suzuki Y, Iwaya T, Terashima M, Saito K, Satodate R  Inactivation of the E-cadherin gene in primary gastric carcinomas and gastric carcinoma cell lines  Jpn J Cancer Res  1996  87:1153-1159  PubMed ID: 9045944   DOI: 10.1111/j.1349-7006.1996.tb03125.x
2179  Tomonaga M, Oka M, Narasaki F, Fukuda M, Nakano R, Takatani H, Ikeda K, Terashi K, Matsuo I, Soda H, Cowan, K H, Kohno S  The multidrug resistance-associated protein gene confers drug resistance in human gastric and colon cancers  Jpn J Cancer Res  1996  87:1263-1270  PubMed ID: 9045962   DOI: 10.1111/j.1349-7006.1996.tb03142.x
2061  Sugimoto H, Nishino H  [Effect of recombinant human basic fibroblast growth factor (bFGF) on the growth of human tumor cell lines]  Hum Cell  1996  9:129-40  PubMed ID: 9183641  
2063  Wang, D., S., Ueno, Y., Oyamada, H., and Kojima, S.  Radioimmunoimaging of Human Colorectal Adenocarcinoma with a Monoclonal Antibody, NCC-CO-411, Against a Human Carcinoembryonic Antigen  Antibody, Immunoconjugates, and Radiopharmaceuticals  1995  8:129-143   
6407  Matsushima Y, Kinoshita Y, Nakata H, Inomoto-Naribayashi Y, Asahara M, Kawanami C, Nakamura A, Ito M, Matsui T, Fujiwara T, et al.  Gastrin receptor gene expression in several human carcinomas.  Jpn J Cancer Res  1994  85(8):819-24  PubMed ID: 7928627   DOI: 10.1111/j.1349-7006.1994.tb02953.x



Back Back Return Top Page