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17775
Yusuke Takizawa*, Koume Yoda, Miho Ishii, Yuka Nagai, Takuro Kurita, Takanori Nakajima
The influence of 2-acetyl-4(5)-tetrahydroxybutylimidazole (THI) in caramel coloring III on gastrointestinal epithelial cells
J. Excipients and Food Chem
2023
14:22-32
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18073
Nor Azlin Safina Abdul Aziz, Maslinda Musa, Siti Hamimah Sheikh Abdul Kadir, Zeti Rahayu Abdul Karim, Narimah Abdul Hamid Hasani
Overexpression of Bactericidal/Permeability-Increasing Fold-Containing Family BPIFB1 in Gastric Cancer Cells Leads to Differential Expression of E-Cadherin and MUC5AC
Biology Bulletin
2023
DOI: 10.1134/s1062359022601756
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21269
Saito-Adachi M, Hama N, Totoki Y, Nakamura H, Arai Y, Hosoda F, Rokutan H, Yachida S, Kato M, Fukagawa A, Shibata T.
Oncogenic structural aberration landscape in gastric cancer genomes.
Nat Commun
2023
14(1):3688
PubMed ID: 37349325
DOI: 10.1038/s41467-023-39263-1
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21361
Wu C, Li D, Cheng X, Gu H, Qian Y, Feng L.
Downregulation of cancer-associated fibroblast exosome-derived miR-29b-1-5p restrains vasculogenic mimicry and apoptosis while accelerating migration and invasion of gastric cancer cells via immunoglobulin domain-containing 1/zonula occluden-1 axis.
Cell Cycle
2023
1-20
PubMed ID: 37587724
DOI: 10.1080/15384101.2023.2231740
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17567
Takashima Y, Komatsu S, Ohashi T, Kiuchi J, Kamiya H, Shimizu H, Arita T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E.
Overexpression of Tetraspanin31 contributes to malignant potential and poor outcomes in gastric cancer
Cancer Sci
2022
113(6):1984-1998
PubMed ID: 35307915
DOI: 10.1111/cas.15342
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20459
Kato S, Shiozaki A, Kudou M, Shimizu H, Kosuga T, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
TRPV2 Promotes Cell Migration and Invasion in Gastric Cancer via the Transforming Growth Factor-β Signaling Pathway.
Ann Surg Oncol
2022
PubMed ID: 34855064
DOI: 10.1245/s10434-021-11132-5
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20622
Takaki W, Konishi H, Matsubara D, Shoda K, Arita T, Kataoka S, Shibamoto J, Furuke H, Takabatake K, Shimizu H, Komatsu S, Shiozaki A, Kubota T, Okamoto K, Otsuji E.
Role of Extracellular High-Mobility Group Box-1 as a Therapeutic Target of Gastric Cancer.
Int J Mol Sci
2022
23(6)
PubMed ID: 35328684
DOI: 10.3390/ijms23063264
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20633
Chen Y, Jiang L, Xia L, Zhang G, Chen L.
ThPOK inhibits the immune escape of gastric cancer cells by inducing STPG1 to inactivate the ERK pathway.
BMC Immunol
2022
23(1):16
PubMed ID: 35379170
DOI: 10.1186/s12865-022-00485-5
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20661
Inoue H, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
Functions and Clinical Significance of CACNA2D1 in Gastric Cancer.
Ann Surg Oncol
2022
PubMed ID: 35445337
DOI: 10.1245/s10434-022-11752-5
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16737
Yusuke Takizawa, Junya Oguri, Masaya Uno, Ami Onsui, Atsushi Ishimura, Takuro Kurita, Takanori Nakajima
Effects of A GLP‑1 Receptor Agonist on Gastrointestinal Epithelial Cells
Scholars Academic Journal of Pharmacy
2022
11:60-66
DOI: 10.36347/sajp.2022.v11i04.002
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17107
Liu B, Katoh H, Komura D, Yamamoto A, Ochi M, Onoyama T, Abe H, Ushiku T, Seto Y, Suo J, Ishikawa S.
Functional genomics screening identifies aspartyl-tRNA synthetase as a novel prognostic marker and a therapeutic target for gastric cancers
J Pathol
2022
2022 Jun 13
PubMed ID: 35696251
DOI: 10.1002/path.5980
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20908
Wang X, Zhang L, Liang Q, Wong CC, Chen H, Gou H, Dong Y, Liu W, Li Z, Ji J, Yu J.
DUSP5P1 promotes gastric cancer metastasis and platinum drug resistance.
Oncogenesis
2022
11(1):66
PubMed ID: 36307394
DOI: 10.1038/s41389-022-00441-3
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17777
Yusuke Takizawa*, Mizuki Arakawa, Takuro Kurita, Takanori Nakajima
The influence of 4-methylimidazole on the gastrointestinal epithelial cells
J. Excipients and Food Chem
2021
12:4-15
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13323
Nishibeppu K, Komatsu S, Kiuchi J, Kishimoto T, Takashima Y, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E.
TRIM37 contributes to malignant outcomes and CDDP resistance in gastric cancer.
J Cancer
2021
PubMed ID: 33391428
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20116
Kurashima K, Shiozaki A, Kudou M, Shimizu H, Arita T, Kosuga T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
LRRC8A influences the growth of gastric cancer cells via the p53 signaling pathway.
Gastric Cancer
2021
PubMed ID: 33864161
DOI: 10.1007/s10120-021-01187-4
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20127
Chen R, Masuo K, Yogo A, Yokoyama S, Sugiyama A, Seno H, Yoshizawa A, Takaishi S.
SNAIL regulates gastric carcinogenesis through CCN3 and NEFL.
Carcinogenesis
2021
42(2):190-201
PubMed ID: 33313663
DOI: 10.1093/carcin/bgaa133
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20148
Kubo H, Murayama Y, Ogawa S, Matsumoto T, Yubakami M, Ohashi T, Kubota T, Okamoto K, Kamiya M, Urano Y, Otsuji E.
β-Galactosidase is a target enzyme for detecting peritoneal metastasis of gastric cancer.
Sci Rep
2021
11(1):10664
PubMed ID: 34021168
DOI: 10.1038/s41598-021-88982-2
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14345
Katsurahara K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
ANO9 regulates PD-L2 expression and binding ability to PD-1 in gastric cancer
Cancer Sci
2021
112(3):1026-1037.
PubMed ID: 33404124
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20224
Ogawa S, Kubo H, Murayama Y, Kubota T, Yubakami M, Matsumoto T, Ohashi T, Okamoto K, Kuriki Y, Hanaoka K, Urano Y, Otsuji E.
Matrix metalloprotease-14 is a Target Enzyme for Detecting Peritoneal Metastasis in Gastric Cancer.
Photodiagnosis Photodyn Ther
2021
PubMed ID: 34242818
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20275
Gao F, Chen X, Lu J, Hu S, Xu H, Shi Y, Feng M, Ding J, Liu H, Luo C, Xie Z, Wang J.
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer.
Eur J Med Chem
2021
215:113274
PubMed ID: 33592537
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20358
Zhang J, Wang F, Zhang H, Cao M.
A novel circular RNA circ_HN1/miR-628-5p/Ecto-5'-nucleotidase competing endogenous RNA network regulates gastric cancer development.
Bioengineered
2021
PubMed ID: 34637682
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20415
Ikari N, Serizawa A, Tanji E, Yamamoto M, Furukawa T.
Analysis of RHOA mutations and their significance in the proliferation and transcriptome of digestive tract cancer cells.
Oncol Lett
2021
22(4):735
PubMed ID: 34466148
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16126
Nakamura K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
The expression of the alpha1 subunit of Na +/K +-ATPase is related to tumor development and clinical outcomes in gastric cancer
Gastric Cancer
2021
24(6):1278-1292
PubMed ID: 34251542
DOI: 10.1007/s10120-021-01212-6
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9737
Tomohiro Kohmoto, Kiyoshi Masuda, Katsutoshi Shoda, Rizu Takahashi, Sae Ujiro, Shoichiro Tange, Daisuke Ichikawa, Eigo Otsuji, Issei Imoto
Claudin-6 Is a Single Prognostic Marker and Functions as a Tumor-Promoting Gene in a Subgroup of Intestinal Type Gastric Cancer
Gastric Cancer
2020
23(3):403-417
PubMed ID: 31654186
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12060
Nishibeppu K, Komatsu S, Imamura T, Kiuchi J, Kishimoto T, Arita T, Kosuga T, Konishi H, Kubota T, Shiozaki A, Fujiwara H, Okamoto K, Otsuji E.
Plasma microRNA profiles: identification of miR-1229-3p as a novel chemoresistant and prognostic biomarker in gastric cancer.
Sci Rep
2020
PubMed ID: 32081926
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13454
Wataru Matsunaga, Misa Ichikawa, Takahiro Ishikawa, Akinobu Gotoh
Lentiviral vector-mediated transfection of human cancer cell lines with tumor suppressor genes inhibits proliferation in vitro
Personalized Medicine Universe
2020
DOI: 10.46459/pmu.2020001
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14804
Xing M, Ooi WF, Tan J, Qamra A, Lee PH, Li Z, Xu C, Padmanabhan N, Lim JQ, Guo YA, Yao X, Amit M, Ng LM, Sheng T, Wang J, Huang KK, Anene-Nzelu CG, Ho SWT, Ray M, Ma L, Fazzi G, Lim KJ, Wijaya GC, Zhang S, Nandi T, Yan T, Chang MM, Das K, Isa ZFA, Wu J, Poon PSY, Lam YN, Lin JS, Tay ST, Lee MH, Tan ALK, Ong X, White K, Rozen SG, Beer M, Foo RSY, Grabsch HI, Skanderup AJ, Li S, Teh BT, Tan P.
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer
J Clin Invest
2020
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11202
Shiozaki A, Ariyoshi Y, Iitaka D, Kosuga T, Shimizu H, Kudou M, Konishi T, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Marunaka Y, Ichikawa D, Otsuji E.
Functional analysis and clinical significance of sodium iodide symporter expression in gastric cancer.
Gastric Cancer
2019
PubMed ID: 30191346
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11511
Behan FM, Iorio F, Picco G, Gonçalves E, Beaver CM, Migliardi G, Santos R, Rao Y, Sassi F, Pinnelli M, Ansari R, Harper S, Jackson DA, McRae R, Pooley R, Wilkinson P, van der Meer D, Dow D, Buser-Doepner C, Bertotti A, Trusolino L, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ.
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature
2019
PubMed ID: 30971826
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9810
Junko Shibato, Fumiko Takenoya, Takahiro Hirabayashi, Ai Kimura, Yusuke Iwasaki, Yoko Toyoda, Motohide Hori, Shigeru Tamogami, Randeep Rakwal, Seiji Shioda
Towards Identification of Bioactive Compounds in Cold Vacuum Extracted Double Cherry Blossom (Gosen-Sakura) Leaves
Plant Signal Behav
2019
14(10):e1644594
PubMed ID: 31342859
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12282
Taslima T Lina, Jazmin Gonzalez, Irina V Pinchuk, Ellen J Beswick, Victor E Reyes
Helicobacter pylori elicits B7H3 expression on gastric epithelial cells: Implications in local T cell regulation and subset development during infection
Clin Oncol Res
2019
2(5)
PubMed ID: 31998864
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12448
Zhang B, Zhang X, Jin M, Hu L, Zang M, Qiu W, Wang S, Liu B, Liu S, Guo D.
CagA increases DNA methylation and decreases PTEN expression in human gastric cancer
Mol Med Rep
2019
19(1):309-319
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10725
Nakamura A, Matsunaga W, Gotoh A.
Autophagy Induced by Naftopidil Inhibits Apoptosis of Human Gastric Cancer Cells.
Anticancer Res.
2018
38:803-809
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Kurata A, Yamada M, Ohno SI, Inoue S, Hashimoto H, Fujita K, Takanashi M, Kuroda M.
Expression level of microRNA-200c is associated with cell morphology in vitro and histological differentiation through regulation of ZEB1/2 and E-cadherin in gastric carcinoma.
Oncol. Rep.
2018
PubMed ID: 29138864
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Kiuchi J, Komatsu S, Imamura T, Nishibeppu K, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Ichikawa D, Tsuda H, Otsuji E.
Overexpression of YEATS4 contributes to malignant outcomes in gastric carcinoma.
Am J Cancer Res
2018
PubMed ID: 30662802
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14272
Krishnan V, Chong YL, Tan TZ, Kulkarni M, Bin Rahmat MB, Tay LS, Sankar H, Jokhun DS, Ganesan A, Chuang LSH, Voon DC, Shivashankar GV, Thiery JP, Ito Y.
TGFβ Promotes Genomic Instability after Loss of RUNX3
Cancer Res
2018
78(1):88-102
PubMed ID: 29074538
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14733
Imamura T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Ohashi T, Kiuchi J, Nishibeppu K, Kosuga T, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E.
Overexpression of ZRF1 is related to tumor malignant potential and a poor outcome of gastric carcinoma
Carcinogenesis
2018
39(2):263-271
PubMed ID: 29228320
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9978
Kneissl J, Hartmann A, Pfarr N, Erlmeier F, Lorber T, Keller S, Zwingenberger G, Weichert W, Luber B.
Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines.
J. Cancer Res. Clin. Oncol.
2017
143:573-600
PubMed ID: 27933395
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10112
Asano M, Sakaguchi M, Tanaka S, Kashimura K, Mitani T, Kawase M, Matsumura H, Yamaguchi T, Fujita Y, Tabuse K.
Effects of Normothermic Conditioned Microwave Irradiation on Cultured Cells Using an Irradiation System with Semiconductor Oscillator and Thermo-regulatory Applicator.
Sci Rep
2017
7:41244
PubMed ID: 28145466
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Lin Z, Lai S, He X, Zhuo W, Wang L, Si J, Chen S.
Decreased long non-coding RNA MTM contributes to gastric cancer cell migration and invasion via modulating MT1F.
Oncotarget
2017
8:97371-97383
PubMed ID: 29228617
DOI: 10.18632/oncotarget.22126
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5804
Authors: Takashi Okuda Tomohiko Taki Kazuhiro Nishida Yoshiaki Chinen Hisao Nagoshi Chouhei Sakakura Masafumi Taniwaki
Molecular heterogeneity in the novel fusion gene APIP-FGFR2: Diversity of genomic breakpoints in gastric cancer with high-level amplifications at 11p13 and 10q26
Oncology Letters
2017
13(1):215-221
PubMed ID: 28123544
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14271
Muguruma N, Okamoto K, Nakagawa T, Sannomiya K, Fujimoto S, Mitsui Y, Kimura T, Miyamoto H, Higashijima J, Shimada M, Horino Y, Matsumoto S, Hanaoka K, Nagano T, Shibutani M, Takayama T.
Molecular imaging of aberrant crypt foci in the human colon targeting glutathione S-transferase P1-1
Sci Rep
2017
7(1):6536
PubMed ID: 28747791
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Kosuga T, Shiozaki A, Kudou M, Yamazato Y, Ichikawa D, Komatsu S, Konishi H, Okamoto K, Shoda K, Arita T, Morimura R, Murayama Y, Kuriu Y, Ikoma H, Nakanishi M, Fujiwara H, Marunaka Y, Otsuji E.
Blockade of potassium ion transports enhances hypotonicity-induced cytocidal effects in gastric cancer
Oncotarget
2017
8(60):101394-101405
PubMed ID: 29254173
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14744
Ohashi T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Imamura T, Kiuchi J, Kosuga T, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E.
Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcinoma
Br J Cancer
2017
116(2):218-226
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Maejima R et al
Enhanced expression of semaphorin 3E is involved in the gastric cancer development.
Int J Oncol
2016
49(3):887-94
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Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells.
Cancer Sci
2016
107(12):1919-1928
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Koichiro Hayashi, Wataru Sakamoto, Toshinobu Yogo
Smart Ferrofluid with Quick Gel Transformation in Tumors for MRI-Guided Local Magnetic Thermochemotherapy
Advanced Functional Materials
2016
26:1708-1718
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Zhou J, Yong WP, Yap CS, Vijayaraghavan A, Sinha RA, Singh BK, Xiu S, Manesh S, Ngo A, Lim A, Ang C, Xie C, Wong FY, Lin SJ, Wan WK, Tan IB, Flotow H, Tan P, Lim KH, Yen PM, Goh LK.
An integrative approach identified genes associated with drug response in gastric cancer.
Carcinogenesis
2015
36:441-51
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14961
Angiopoietin-like protein 2 is a potential biomarker for gastric cancer
Angiopoietin-like protein 2 is a potential biomarker for gastric cancer
Molecular Medicine Reports
2015
11:2653-2658
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Honda S, Loher P, Shigematsu M, Palazzo JP, Suzuki R, Imoto I, Rigoutsos I, Kirino Y.
Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers
Proc Natl Acad Sci U S A
2015
112(29):E3816-25
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Helicobacter pylori cag pathogenicity island's role in B7-H1 induction and immune evasion
PLoS One
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10(3):e0121841
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Sato M, Muguruma N, Nakagawa T, Okamoto K, Kimura T, Kitamura S, Yano H, Sannomiya K, Goji T, Miyamoto H, Okahisa T, Mikasa H, Wada S, Iwata M, Takayama T.
High antitumor activity of pladienolide B and its derivative in gastric cancer.
Cancer Sci
2014
105(1):110-6
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Matsumoto H, Tsuchiya T, Yoshiura K, Hayashi T, Hidaka S, Nanashima A, Nagayasu T.
ABCC11/MRP8 Expression in the Gastrointestinal Tract and a Novel Role for Pepsinogen Secretion.
Acta Histochem Cytochem
2014
47(3):85-94
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Fawzy A. Attaby, Azza M. Abdel-Fattah, Labeeb M. Shaif, Mohamed M. Elsayed
Synthesis, Reactions, Characterization and Biological Evaluation of 2,3′-Bipyridine Derivatives (III)
Journal of Heterocyclic Chemistry
2014
51:927-936
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18077
Shiho Sakuma, Eiko Otake, Kan Torii, Motoki Nakamura, Akira Maeda, Ryoto Tujii, Haruo Akashi, Hiromi Ohi, Shigenobu Yano, Akimichi Morita
Photodynamic therapy with glycoconjugated chlorin photosensitizer
Journal of Porphyrins and Phthalocyanines
2013
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Konno-Shimizu M1, Yamamichi N, Inada K, Kageyama-Yahara N, Shiogama K, Takahashi Y, Asada-Hirayama I, Yamamichi-Nishina M, Nakayama C, Ono S, Kodashima S, Fujishiro M, Tsutsumi Y, Ichinose M, Koike K.
Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.
PLoS One
2013
8(2):e56766
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CagA-dependent downregulation of B7-H2 expression on gastric mucosa and inhibition of Th17 responses during Helicobacter pylori infection
J Immunol
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Miyato H, Tsuno NH, Kitayama J.
Semaphorin 3C is involved in the progression of gastric cancer.
Cancer Sci
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Identification of a potent epigenetic biomarker for resistance to camptothecin and poor outcome to irinotecan-based chemotherapy in colon cancer.
Int J Oncol
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Human leukocyte antigen-G is closely associated with tumor immune escape in gastric cancer by increasing local regulatory T cells.
Cancer Sci
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102(7):1272-80
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Synthesis and antitumor activity of novel benzimidazole-5-carboxylic acid derivatives and their transition metal complexes as topoisomerease II inhibitors.
Eur J Med Chem
2010
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New pyrazoles incorporating pyrazolylpyrazole moiety: synthesis, anti-HCV and antitumor activity
Eur J Med Chem
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Novel Synthesis, Reactions and anti-Cancer Activities of 4,4'-Benzene-1,4- diylbis(6-phenyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile)
Current Organic Chemistry
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Synthesis, tautomerism, and antimicrobial, anti-HCV, anti-SSPE, antioxidant, and antitumor activities of arylazobenzosuberones.
Bioorg Med Chem
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Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
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Oncol Rep
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Mol Cancer Ther
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Pathol Res Pract
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Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells.
Exp Cell Res
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301:168-78
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5935
Dan S, Shirakawa M, Mukai Y, Yoshida Y, Yamazaki K, Kawaguchi T, Matsuura M, Nakamura Y, Yamori T.
Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
Cancer Sci
2003
94(12):1074-82
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Nakamura K, Uenaka T, Nagasu T, Sugumi H, Yamaguchi A, Kotake Y, Okada T, Kamata J, Niijima J, Taniguchi T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K.
A novel carbazole topoisomerase II poison, ER-37328: potent tumoricidal activity against human solid tumors in vitro and in vivo.
Cancer Sci
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Antitumor activity of ER-37328, a novel carbazole topoisomerase II inhibitor.
Mol Cancer Ther
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Survivin expression in tumor cell nuclei is predictive of a favorable prognosis in gastric cancer patients.
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Alpha-fetoprotein producing gastric cancer lacks transcription factor ATBF1
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Human canalicular multispecific organic anion transporter (cMOAT) is expressed in human lung, gastric, and colorectal cancer cells
Biochem Biophys Res Commun
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Cytotoxicity and electron microscopy of cell death induced by goniothalamin
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Ginseng total saponin inhibits the dopaminergic depletions induced by methamphetamine
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Accumulation of NCC-CO-411 monoclonal antibody in human colorectal adenocarcinoma through binding of the released carcinoembryonic antigen in nude mice.
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Inactivation of the E-cadherin gene in primary gastric carcinomas and gastric carcinoma cell lines
Jpn J Cancer Res
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The multidrug resistance-associated protein gene confers drug resistance in human gastric and colon cancers
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Radioimmunoimaging of Human Colorectal Adenocarcinoma with a Monoclonal Antibody, NCC-CO-411, Against a Human Carcinoembryonic Antigen
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Gastrin receptor gene expression in several human carcinomas.
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