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Cell No. : Cell Name
RCB0489 : NEC8  update : 2018/07/06
CommentEmbryonal carcinoma, testis.
Comment from the depositor
Terms and conditionsBasically, there is no restriction regarding academic use.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Motoyama, Teiichi
Originator Motoyama, Teiichi
Year of deposit 1990
Animal human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Male
Age at sampling 24 years
Tissue testis
Case history teratocarcinoma
Classification cancer
History Motoyama - JCRB(FDSC0005)
Memo_1 Mycoplasma was eliminated with MC-210 by the depositor.
Lifespan infinite
Morphology other
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives RPMI1640 + 10% FBS
Antibiotics Free
Passage method pipetting
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : once/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR(human) OK
Virus (HIV) (-)
Isozyme LD, NP, MPI
Chromosome mode 59-132(50) : /60(2),62(7),63(2),64(6),65(8),66(11)/
Images
deposit info
lot info
Reference information Reference 2
User's Publication 16


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Reference
1729  Motoyama T, Watanabe H, Yamamoto T, Sekiguchi M  Production of alpha-fetoprotein by human germ cell tumors in vivo and in vitro.  Acta Pathol Jpn  1987  37:1263-77  PubMed ID: 2445169
1728  Motoyama T, Watanabe H, Yamamoto T, Sekiguchi M  Human testicular germ cell tumors in vitro and in athymic nude mice.  Acta Pathol Jpn  1987  37:431-48  PubMed ID: 3618218

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User's Publication
11326  Abe T, Kohashi K, Takemoto J, Kinoshita F, Eto M, Oda Y.  Clinicopathological Significance and Antitumor Effect of MPHOSPH1 in Testicular Germ Cell Tumor.  J Cancer  2018    PubMed ID: 30519350
7130  Kita H, Okamoto K, Kushima R, Kawauchi A, Chano T.  Dimethyl sulfoxide induces chemotherapeutic resistance in the treatment of testicular embryonal carcinomas.  Oncol Lett  2015  10:661-666  PubMed ID: 26622550
6384  Hidenori Kawashima Sakae Masaki Marie Kawamura  Induction of HLA‑A* 33‑restricted cytotoxic lymphocytes against renal cell carcinoma targeting galectin 9 and PINCH  Biomedical Reports  2014  2:809-812 
6390  Kawashima H, Obayashi A, Kawamura M, Masaki S, Tamada S, Iguchi T, Uchida J, Kuratsukuri K, Tanaka T, Nakatani T.  Galectin 9 and PINCH, novel immunotherapy targets of renal cell carcinoma: a rationale to find potential tumour antigens and the resulting cytotoxic T lymphocytes induced by the derived peptides.  BJU Int  2014  113(2):320-32  PubMed ID: 24895689
6395  Ando S, Matsuoka T, Kawai K, Sugita S, Joraku A, Kojima T, Suetomi T, Miyazaki J, Fujita J, Nishiyama H.  Expression of the oncoprotein gankyrin and phosphorylated retinoblastoma protein in human testis and testicular germ cell tumor.  Int J Urol  2014  21(10):992-8  PubMed ID: 24861729
6398  Nagano K, Yamashita T, Inoue M, Higashisaka K, Yoshioka Y, Abe Y, Mukai Y, Kamada H, Tsutsumi Y, Tsunoda S  Eph receptor A10 has a potential as a target for a prostate cancer therapy.  Biochem Biophys Res Commun  2014  450(1):545-9  PubMed ID: 24924629
6385  Ushida H, Chano T, Minami K, Kita H, Kawakami T, Okabe H, Okada Y, Okamoto K.  Therapeutic potential of SOX2 inhibition for embryonal carcinoma.  J Urol  2012  187(5):1876-81  PubMed ID: 22425046
6391  Fujitani N, Takegawa Y, Ishibashi Y, Araki K, Furukawa J, Mitsutake S, Igarashi Y, Ito M, Shinohara Y.  Qualitative and quantitative cellular glycomics of glycosphingolipids based on rhodococcal endoglycosylceramidase-assisted glycan cleavage, glycoblotting-assisted sample preparation, and matrix-assisted laser desorption ionization tandem time-of-flight mass spectrometry analysis.  J Biol Chem  2011  286(48):41669-79  PubMed ID: 21965662
6394  Behjati R, Kawai K, Inadome Y, Kano J, Akaza H, Noguchi M.  APAF-1 is related to an undifferentiated state in the testicular germ cell tumor pathway.  Cancer Sci  2011  102(1):267-74  PubMed ID: 20977544
6387  Minami K, Chano T, Kawakami T, Ushida H, Kushima R, Okabe H, Okada Y, Okamoto K.  DNMT3L is a novel marker and is essential for the growth of human embryonal carcinoma.  Clin Cancer Res  2010  16(10):2751-9  PubMed ID: 20460473
6388  Ogino H, Nakayama R, Sakamoto H, Yoshida T, Sugimura T, Masutani M.  Analysis of poly(ADP-ribose) polymerase-1 (PARP1) gene alteration in human germ cell tumor cell lines.  Cancer Genet Cytogenet  2010  197(1):8-15  PubMed ID: 20113831
3374  Yanagisawa, Ayano, Endo, Chisato, Okawa, Katsuya, Shitara, Shingo, Kugoh, Hiroyuki, Kakitani, Makoto, Oshimura, Mitsuo, Tomizuka, Kazuma  Generation of chromosome-specific monoclonal antibodies using in vitro-differentiated transchromosomic mouse embryonic stem cells.  Stem Cells  2005  23:1479-88  PubMed ID: 16081665
2888  Sekiguchi T, Iida H, Fukumura J, Nishimoto T  Human DDX3Y, the Y-encoded isoform of RNA helicase DDX3, rescues a hamster temperature-sensitive ET24 mutant cell line with a DDX3X mutation.  Exp Cell Res  2004  300:213-22  PubMed ID: 15383328
6397  Shirakawa T, Gotoh A, Zhang Z, Kao C, Chung LW, Gardner TA.  Development of human chorionic gonadotropin subunit-beta promoter-based toxic gene therapy for testicular cancer.  Urology  2004  63(3):613-8  PubMed ID: 15028478
6389  Iwashita S, Koyama K, Nakamura Y.  VNTR sequence on human chromosome 11p15 that affects transcriptional activity.  J Hum Genet  2001  46(12):717-21  PubMed ID: 11776385
6392  Nadano D, Aoki C, Yoshinaka T, Irie S, Sato TA.  Electrophoretic characterization of ribosomal subunits and proteins in apoptosis: specific downregulation of S11 in staurosporine-treated human breast carcinoma cells.  Biochemistry.   2001  40(50):15184-93  PubMed ID: 11735401



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