細胞番号 : 細胞名
RCB0487 : CHP-134
update : 2024/12/23
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| 細胞特性(Comment:英) | Human cell line derived from Neuroblastoma. N-myc gene is amplified. Application consideration |
| 細胞特性(日) | ヒト神経芽細胞腫由来細胞株。N-myc遺伝子の増幅がある。培養開始にあたっての注意 |
| 細胞特性(寄託者記述:英) | |
| 細胞特性(寄託者記述:日) | |
| 使用条件(英) | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
| 使用条件(日) | 基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。 |
| 備考(英) | |
| 備考(日) | |
| 提供申込書類(英) |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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| 提供申込書類(日) |
依頼書C-0001.pdf
同意書(非営利学術目的)C-0003.pdf
同意書(営利目的)C-0003p.pdf
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提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください（詳細）。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
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| 提供手数料 |
手数料とお支払いについてはこちらをご覧ください。 |
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細胞基本情報
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寄託者 |
Nishi, Yoshisuke
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| 樹立者 |
Schlesinger, H. R.
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| 寄託日 |
1990
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| 動物種 |
_human
< Mammals
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| 属名 |
Homo
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| 種名 |
sapiens
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| 性別 |
Male
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| 齢 |
13 months
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| 採取組織 |
adrenal, left
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| 病名 |
neuroblastoma (stage IV)
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| 細胞分類 |
cancer
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| 入手歴 |
Latt, S. A.
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|
細胞寿命 |
infinite
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| 細胞形態 |
other
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| Cellosaurus(Expasy) |
CVCL_1124
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細胞培養・検査情報
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寄託時情報 |
ロット情報 |
| 培地・試薬情報 |
培地・試薬一覧はこちらをご覧ください。 |
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培養形態 |
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Adherent cells
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| 培地 |
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RPMI1640 + 10% FBS
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| 抗生物質 |
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Free
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継代方法 |
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0.25% Trypsin (1min.) or pipetting
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|
継代密度 |
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1 : 4 split
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| 継代・培地交換頻度 |
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Subculture : 1-2 times/week, Medium Renewal : 2 times/week
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| 培養最適温度 |
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37
℃
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| 二酸化炭素濃度 |
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5
%
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| 凍結培地 |
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Medium + 10% DMSO
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| 凍結方法 |
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Slow freezing
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| マイコプラズマ/アコレプラズマ |
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(-)
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| ウィルス（HIV) |
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(-)
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| アイソザイム検査 |
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LD, NP, AST, MPI
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| 染色体検査 |
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44-47(50) : 44(1),45(6),46(41),47(2)
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| 個体識別検査 |
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OK
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| 画像情報 |
寄託時情報 | ロット情報 |
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| 文献情報 |
Reference(英) |
5件
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| Reference(日) |
0件
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| 利用者成果(英) |
13件
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| 利用者成果(日) |
0件
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| Reference(英) |
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1287
Gilbert F, Feder M, Balaban G, Brangman D, Lurie, D K, Podolsky R, Rinaldt V, Vinikoor N, Weisband J
Human neuroblastomas and abnormalities of chromosomes 1 and 17.
Cancer Res
1984
44:5444-9
PubMed ID: 6488196
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246
Schwab M, Alitalo K, Klempnauer KH, Varmus HE, Bishop JM, Gilbert F, Brodeur G, Goldstein M, Trent J.
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
Nature
1983
305(5931):245-8
PubMed ID: 6888561
DOI: 10.1038/305245a0
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1286
U V Santer, M C Glick
Presence of fucosyl residues on the oligosaccharide antennae of membrane glycopeptides of human neuroblastoma cells
Cancer Res
1983
43(9):4159-66
PubMed ID: 6871857
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1127
Gilbert F, Balaban G, Moorhead P, Bianchi D, Schlesinger H
Abnormalities of chromosome 1p in human neuroblastoma tumors and cell lines.
Cancer Genet Cytogenet
1982
7:33-42
PubMed ID: 7139592
DOI: 10.1016/0165-4608(82)90105-4
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1215
Schlesinger, H R, Gerson, J M, Moorhead, P S, Maguire H, Hummeler K
Establishment and characterization of human neuroblastoma cell lines.
Cancer Res
1976
36:3094-100
PubMed ID: 10079
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| 利用者成果(英) |
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21777
Kato A, Iwasaki R, Takeshima K, Maruzuru Y, Koyanagi N, Natsume T, Kusano H, Adachi S, Kawano S, Kawaguchi Y.
Identification of a novel neurovirulence factor encoded by the cryptic orphan gene UL31.6 of herpes simplex virus 1.
J Virol
2024
e0074724
PubMed ID: 38819171
DOI: 10.1128/jvi.00747-24
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19684
Ando K, Suenaga Y, Kamijo T.
DNA Ligase 4 Contributes to Cell Proliferation against DNA-PK Inhibition in MYCN-Amplified Neuroblastoma IMR32 Cells
Int J Mol Sci
2023
24(10):9012
PubMed ID: 37240360
DOI: 10.3390/ijms24109012
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21471
Hasan MN, Hyodo T, Biswas M, Rahman ML, Mihara Y, Karnan S, Ota A, Tsuzuki S, Hosokawa Y, Konishi H.
Flow cytometry-based quantification of genome editing efficiency in human cell lines using the L1CAM gene.
PLoS One
2023
18(11):e0294146
PubMed ID: 37943774
DOI: 10.1371/journal.pone.0294146
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22291
Lu F, Mu B, Jin G, Zhu L, Mu P.
MYCN Directly Targets NeuroD1 to Promote Cellular Proliferation in Neuroblastoma
Oncol Res
2022
29(1):1-10.
PubMed ID: 34937609
DOI: 10.3727/096504021X16401852341873
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20297
Liu C, Gen Y, Tanimoto K, Muramatsu T, Inoue J, Inazawa J.
Concurrent targeting of MAP3K3 and BRD4 by miR-3140-3p overcomes acquired resistance to BET inhibitors in neuroblastoma cells.
Mol Ther Nucleic Acids
2021
25:83-92
PubMed ID: 34258104
DOI: 10.1016/j.omtn.2021.05.001
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20445
Komata Y, Tsubota S, Sakamoto K, Ikematsu S, Kadomatsu K.
Screening of novel Midkine binding protein by BioID2-based proximity labeling.
Nagoya J Med Sci
2021
83(3):495-508
PubMed ID: 34552285
DOI: 10.18999/nagjms.83.3.495
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13221
Ando K, Cázares-Ordoñez V, Makishima M, Yokoyama A, Suenaga Y, Nagase H, Kobayashi S, Kamijo T, Koshinaga T, Wada S.
CEP131 Abrogates CHK1 Inhibitor-Induced Replication Defects and Is Associated with Unfavorable Outcome in Neuroblastoma.
J Oncol
2020
PubMed ID: 33014050
DOI: 10.1155/2020/2752417
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15663
Tanimoto T, Tazawa H, Ieda T, Nouso H, Tani M, Oyama T, Urata Y, Kagawa S, Noda T, Fujiwara T.
Elimination of MYCN-Amplified Neuroblastoma Cells by Telomerase-Targeted Oncolytic Virus via MYCN Suppression
Mol Ther Oncolytics
2020
18:14-2
PubMed ID: 32637577
DOI: 10.1016/j.omto.2020.05.015
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14883
Ando K, Nakamura Y, Nagase H, Nakagawara A, Koshinaga T, Wada S, Makishima M.
Co-Inhibition of the DNA Damage Response and CHK1 Enhances Apoptosis of Neuroblastoma Cells
Int J Mol Sci
2019
20(15):3700
PubMed ID: 31362335
DOI: 10.3390/ijms20153700
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14739
Takagi M, Yoshida M, Nemoto Y, Tamaichi H, Tsuchida R, Seki M, Uryu K, Nishii R, Miyamoto S, Saito M, Hanada R, Kaneko H, Miyano S, Kataoka K, Yoshida K, Ohira M, Hayashi Y, Nakagawara A, Ogawa S, Mizutani S, Takita J.
Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor
J Natl Cancer Inst
2017
109(11)
PubMed ID: 29059438
DOI: 10.1093/jnci/djx062
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18920
Nishio N, Fujita M, Tanaka Y, Maki H, Zhang R, Hirosawa T, Demachi-Okamura A, Uemura Y, Taguchi O, Takahashi Y, Kojima S, Kuzushima K.
Zoledronate sensitizes neuroblastoma-derived tumor-initiating cells to cytolysis mediated by human γδ T cells
J Immunother
2012
35(8):598-606
PubMed ID: 22996365
DOI: 10.1097/CJI.0b013e31826a745a
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2916
Abe, Masanobu, Ohira, Miki, Kaneda, Atsushi, Yagi, Yukiko, Yamamoto, Seiichiro, Kitano, Yoshihiro, Takato, Tsuyoshi, Nakagawara, Akira, Ushijima, Toshikazu
CpG island methylator phenotype is a strong determinant of poor prognosis in neuroblastomas.
Cancer Res
2005
65:828-34
PubMed ID: 15705880
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2347
Matsui T, Sano K, Tsukamoto T, Ito M, Takaishi T, Nakata H, Nakamura H, Chihara K.
Human neuroblastoma cells express alpha and beta platelet-derived growth factor receptors coupling with neurotrophic and chemotactic signaling
J Clin Invest
1993
92(3):1153-60
PubMed ID: 8376577
DOI: 10.1172/JCI116684
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