Cell No. : Cell Name
RCB0481 : TNB1
update : 2022/04/15
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Comment | Human cell line derived from Neuroblastoma. N-myc gene is amplified. Another name is TGW (PMID: 2335222). Application consideration |
Comment from the depositor | |
Terms and conditions | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
Remarks | |
Order Form |
Order Form(C-0005.pdf)
 
MTA(C-0007.pdf)
 
MTA(C-0007p.pdf)
 
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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Basic information
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Depositor |
Nishi, Yoshisuke
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Originator |
Tsuchida, Yoshiaki
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Year of deposit |
1990
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Animal |
_human
< Mammals
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Genus |
Homo
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Species |
sapiens
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Gender |
Male
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Age at sampling |
20 months
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Tissue |
neuroblastoma
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Disease name |
neuroblastoma
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Metastatic ability |
Yes
|
Metastatic tissue |
mediastinum
|
Classification |
cancer
|
History |
Latt, S. A. - Tsuchida, Y.
|
|
Lifespan |
infinite
|
Morphology |
other
|
Cellosaurus(Expasy) |
CVCL_A443
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| |
deposit info |
lot info |
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Medium |
Medium List |
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Culture type |
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Adherent/Suspension cells
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Culture medium |
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RPMI1640 + 15% FBS
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Antibiotics |
|
Free
|
|
Passage method |
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dilution
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Culture information
|
Passage ratio |
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1 : 10 split
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SC frequency |
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Subculture : once/week, Medium Renewal : 2 times/week
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Temperature |
|
37
℃
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CO2 concentration |
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5
%
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Freeze medium |
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Medium + 10% DMSO
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Freezing method |
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Slow freezing
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Mycoplasma |
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(-)
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Virus (HIV) |
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(-)
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Isozyme |
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LD, NP
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Chromosome mode |
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46-97(50) : 46(4),47(8),48(32),49(2),50(1),73(1)/
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STR(human) |
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OK
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Reference information |
Reference |
6
|
User's Publication |
6
|
Reference |
4690
Tsuchida Y, Sekiguchi M, Kaneko Y, Kanda N.
Origin of human neuroblastoma cell lines TGW and TNB1.
FEBS Lett
1990
263(2):191
PubMed ID: 2335222
DOI: 10.1016/0014-5793(90)81370-4
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4692
Tsuchida Y1, Yokomori K, Kanda N, Kaneko Y, Shimatake H, Hashizume K.
Human neuroblastoma cell line TNB1 and its biological characteristics
Hum Cell
1989
2(2):202-3
PubMed ID: 2577250
|
4691
Tsuchida Y1, Kanda N, Shimatake H, Kaneko Y, Notomi T.
Clinical significance of gene amplification studied in human neuroblastoma xenografts: relationship with tumor growth rate, chemotherapeutic sensitivities and levels of neuron-specific enolase.
Exp Cell Biol
1988
56(5):277-84
PubMed ID: 3229554
DOI: 10.1159/000163491
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245
Kanda N, Tsuchida Y, Hata J, Kohl NE, Alt FW, Latt SA, Utakoji T.
Amplification of IMR-32 clones 8, G21, and N-myc in human neuroblastoma xenografts
Cancer Res
1987
47(12):3291-5
PubMed ID: 3034408
|
244
Kaneko Y, Tsuchida Y, Maseki N, Takasaki N, Sakurai M, Saito S.
Chromosome findings in human neuroblastomas xenografted in nude mice
Jpn J Cancer Res
1985
76(5):359-64
PubMed ID: 3924709
|
1125
Tsuchida Y, Yokomori K, Iwanaka T, Saito S
Nude mouse xenograft study for treatment of neuroblastoma: effects of chemotherapeutic agents and surgery on tumor growth and cell kinetics.
J Pediatr Surg
1984
19:72-6
PubMed ID: 6583377
DOI: 10.1016/s0022-3468(84)80020-2
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User's Publication |
20778
Chen L, Mu B, Li Y, Lu F, Mu P.
DRR1 promotes neuroblastoma cell differentiation by regulating CREB expression.
Pediatr Res
2022
PubMed ID: 35854089
DOI: 10.1038/s41390-022-02192-8
|
10685
Su Z, Kishida S, Tsubota S, Sakamoto K, Cao D, Kiyonari S, Ohira M, Kamijo T, Narita A, Xu Y, Takahashi Y, Kadomatsu K.
Neurocan, an extracellular chondroitin sulfate proteoglycan, stimulates neuroblastoma cells to promote malignant phenotypes.
Oncotarget
2017
8:106296-106310
PubMed ID: 29290949
DOI: 10.18632/oncotarget.22435
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14685
Mu P, Akashi T, Lu F, Kishida S, Kadomatsu K.
A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma
Oncogene
2017
36(41):5745-5756.
PubMed ID: 28604741
DOI: 10.1038/onc.2017.181
|
15135
Nakaguro M, Kiyonari S, Kishida S, Cao D, Murakami-Tonami Y, Ichikawa H, Takeuchi I, Nakamura S, Kadomatsu K.
Nucleolar protein PES1 is a marker of neuroblastoma outcome and is associated with neuroblastoma differentiation
Cancer Sci
2015
106(3):237-43
PubMed ID: 25557119
DOI: 10.1111/cas.12598
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2758
Harada, Hideki, Saijo, Kaoru, Watanabe, Satoru, Tsuboi, Koji, Nose, Tadao, Ishiwata, Isamu, Ohno, Tadao
Selective expansion of human natural killer cells from peripheral blood mononuclear cells by the cell line, HFWT.
Jpn J Cancer Res
2002
93:313-9
PubMed ID: 11927014
DOI: 10.1111/j.1349-7006.2002.tb02174.x
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15591
Miyake I, Hakomori Y, Shinohara A, Gamou T, Saito M, Iwamatsu A, Sakai R.
Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines
Oncogene
2002
21(38):5823-34
PubMed ID: 12185581
DOI: 10.1038/sj.onc.1205735
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