Cell No. : Cell Name
RCB0468 : Lu-135
update : 2022/03/15
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Comment | Small cell carcinoma, variant type. Application consideration |
Comment from the depositor | |
Terms and conditions | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
Remarks | |
Order Form |
Order Form(C-0005.pdf)
 
MTA(C-0007.pdf)
 
MTA(C-0007p.pdf)
 
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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Basic information
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Depositor |
Terasaki, Takeo
|
Originator |
Terasaki, T. & Shimosato, Y.
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Year of deposit |
1990
|
Animal |
human
< Mammals
|
Genus |
Homo
|
Species |
sapiens
|
Race |
Japanese
|
Gender |
Male
|
Age at sampling |
69 years
|
Tissue |
lung
|
Disease name |
small cell carcinoma
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Classification |
cancer
|
Year of origin |
1983
|
|
Lifespan |
infinite
|
Morphology |
other
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Cellosaurus(Expasy) |
CVCL_1389
|
| |
deposit info |
lot info |
|
Medium |
Medium List |
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Culture type |
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Adherent/Suspension cells
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Medium and additives |
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RPMI1640 + 10% FBS
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Antibiotics |
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Free
|
|
Passage method |
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dilution
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Culture information
|
Passage ratio |
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1 : 5 split
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SC frequency |
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Subculture : once/week, Medium Renewal : 2 times/week
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Temperature |
|
37
℃
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CO2 concentration |
|
5
%
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Freeze medium |
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Medium + 10% DMSO
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Freezing method |
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Slow freezing
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Mycoplasma |
|
(-)
|
Virus (HIV) |
|
(-)
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Isozyme |
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LD, NP
|
Chromosome mode |
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27-58(50) : /40(3),41(3),42(6),43(3),45(1),46(4)/
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STR(human) |
|
OK
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Images |
deposit info | lot info |
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Reference information |
Reference |
10
|
User's Publication |
13
|
Reference |
3149
Gemma A, Hosoya Y, Seike M, Uematsu K, Kurimoto F, Hibino S, Yoshimura A, Shibuya M, Kudoh S, Emi M
Genomic structure of the human MAD2 gene and mutation analysis in human lung and breast cancers.
Lung Cancer
2001
32:289-95
PubMed ID: 11390010
|
3150
Tanaka K, Terasaki T
Development and elongation of neurite-like outgrowth on small cell lung cancer cell lines
Oncogene
1997
88:176-183
PubMed ID: 9119746
|
3148
Gemma A, Takenoshita S, Hagiwara K, Okamoto A, Spillare, E A, McMemamin, M G, Hussain, S P, Forrester K, Zariwala M, Xiong Y, Harris, C C
Molecular analysis of the cyclin-dependent kinase inhibitor genes p15INK4b/MTS2, p16INK4/MTS1, p18 and p19 in human cancer cell lines.
Int J Cancer
1996
68:605-11
PubMed ID: 8938142
|
3144
Shimoyama Y, Gotoh M, Terasaki T, Kitajima M, Hirohashi S
Isolation and sequence analysis of human cadherin-6 complementary DNA for the full coding sequence and its expression in human carcinoma cells.
Cancer Res
1995
55:2206-11
PubMed ID: 7743525
|
3141
Ookawa K, Shiseki M, Takahashi R, Yoshida Y, Terada M, Yokota J
Reconstitution of the RB gene suppresses the growth of small-cell lung carcinoma cells carrying multiple genetic alterations.
Oncogene
1993
8:2175-81
PubMed ID: 8393162
|
1368
Matsumoto T, Terasaki T, Mukai K, Wada M, Okamoto A, Yokota J, Yamaguchi K, Kato K, Nagatsu T, Shimosato Y
Relation between nucleolar size and growth characteristics in small cell lung cancer cell lines.
Jpn J Cancer Res
1991
82:820-8
PubMed ID: 1715338
|
3142
Nakagawa K, Yokota J, Wada M, Sasaki Y, Fujiwara Y, Sakai M, Muramatsu M, Terasaki T, Tsunokawa Y, Terada M, et al.
Levels of glutathione S transferase pi mRNA in human lung cancer cell lines correlate with the resistance to cisplatin and carboplatin.
Jpn J Cancer Res
1988
79:301-4
PubMed ID: 2836347
|
1112
Yokota J, Wada M, Yoshida T, Noguchi M, Terasaki T, Shimosato Y, Sugimura T, Terada M
Heterogeneity of lung cancer cells with respect to the amplification and rearrangement of myc family oncogenes.
Oncogene
1988
2:607-11
PubMed ID: 2838790
|
1111
Yokota J, Akiyama T, Fung, Y K, Benedict, W F, Namba Y, Hanaoka M, Wada M, Terasaki T, Shimosato Y, Sugimura T, et al.
Altered expression of the retinoblastoma (RB) gene in small-cell carcinoma of the lung.
Oncogene
1988
3:471-5
PubMed ID: 2856251
|
1118
Terasaki T, Shimosato Y, Nakajima T, Tsumuraya M, Morinaga S, Hirohashi S, Yamaguchi K, Kato K, Ichinose H, Nagatsu T
Changes in cell characteristics due to culture conditions in cell lines from human small cell lung cancer.
Jpn J Clin Oncol
1986
16:203-12
PubMed ID: 3022030
|
User's Publication |
10922
Shigeaki Umeda et al
Loss of IL-24 expression facilitates invasion in lung adenocarcinoma
Int J Clin Exp Pathol
2017
10:173-185
|
15988
Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, Ikehara Y, Narimatsu H.
Glycoproteomics approach for identifying Glycobiomarker candidate molecules for tissue type classification of non-small cell lung carcinoma
J Proteome Res
2014
13(11):4705-16
PubMed ID: 25244057
|
16604
Okudela K, Katayama A, Woo T, Mitsui H, Suzuki T, Tateishi Y, Umeda S, Tajiri M, Masuda M, Nagahara N, Kitamura H, Ohashi K.
Proteome analysis for downstream targets of oncogenic KRAS--the potential participation of CLIC4 in carcinogenesis in the lung
PLoS One
2014
9(2):e87193
PubMed ID: 24503901
|
4390
Ishii J, Sato H, Sakaeda M, Shishido-Hara Y, Hiramatsu C, Kamma H, Shimoyamada H, Fujiwara M, Endo T, Aoki I, Yazawa T.
POU domain transcription factor BRN2 is crucial for expression of ASCL1, ND1 and neuroendocrine marker molecules and cell growth in small cell lung cancer.
Pathol Int
2013
63(3):158-68
PubMed ID: 23530560
|
8174
Takezawa K, Okamoto I, Tsukioka S, Uchida J, Kiniwa M, Fukuoka M, Nakagawa K.
Identification of thymidylate synthase as a potential therapeutic target for lung cancer.
Br. J. Cancer
2010
103:354-61
PubMed ID: 20628382
|
6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
|
12769
Okudela K, Yazawa T, Ishii J, Woo T, Mitsui H, Bunai T, Sakaeda M, Shimoyamada H, Sato H, Tajiri M, Ogawa N, Masuda M, Sugimura H, Kitamura H.
Down-regulation of FXYD3 expression in human lung cancers: its mechanism and potential role in carcinogenesis
Am J Pathol
2009
175(6):2646-56
PubMed ID: 19893046
|
3395
Yonesaka, Kimio, Tamura, Kenji, Kurata, Takayasu, Satoh, Taroh, Ikeda, Masato, Fukuoka, Masahiro, Nakagawa, Kazuhiko
Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin.
Int J Cancer
2006
118:812-20
PubMed ID: 16108013
|
2929
Jones MH, Virtanen C, Honjoh D, Miyoshi T, Satoh Y, Okumura S, Nakagawa K, Nomura H, Ishikawa Y
Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small-cell and large-cell neuroendocrine carcinomas identified by gene expression profiles
Lancet
2004
63:775-781
PubMed ID: 15016488
|
3338
Seike, Masahiro, Kondo, Tadashi, Fujii, Kazuyasu, Yamada, Tesshi, Gemma, Akihiko, Kudoh, Shoji, Hirohashi, Setsuo
Proteomic signature of human cancer cells.
Proteomics
2004
4:2776-88
PubMed ID: 15352251
|
3140
Koh T, Yokota J, Ookawa K, Kina T, Koshimura K, Miwa S, Ariyasu T, Yamada H, Osaka M, Haga H, et al.
Alternative splicing of the neurofibromatosis 1 gene correlates with growth patterns and neuroendocrine properties of human small-cell lung-carcinoma cells.
Int J Cancer
1995
60:843-7
PubMed ID: 7896456
|
6407
Matsushima Y, Kinoshita Y, Nakata H, Inomoto-Naribayashi Y, Asahara M, Kawanami C, Nakamura A, Ito M, Matsui T, Fujiwara T, et al.
Gastrin receptor gene expression in several human carcinomas.
Jpn J Cancer Res
1994
85(8):819-24
PubMed ID: 7928627
|
13657
Ohta S, Honda A, Tokutake Y, Yoshida H, Hanai N.
Antitumor effects of a novel monoclonal antibody with high binding affinity to ganglioside GD3
Cancer Immunol Immunother
1993
36(4):260-6
PubMed ID: 8439988
|