細胞番号 : 細胞名
RCB0467 : Lu-134-B
update : 2024/01/17
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| 細胞特性(Comment:英) | Small cell carcinoma, classic type. See Lu-134-A. Application consideration |
| 細胞特性(日) | 日本人肺小細胞癌。Lu-134-Aと同一患者から、異なる培養条件で樹立された。Ｂの方が培養条件によって細胞の性質が変化する。培養開始にあたっての注意 |
| 細胞特性(寄託者記述:英) | |
| 細胞特性(寄託者記述:日) | |
| 使用条件(英) | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
| 使用条件(日) | 基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。 |
| 備考(英) | |
| 備考(日) | |
| 提供申込書類(英) |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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| 提供申込書類(日) |
依頼書C-0001.pdf
同意書(非営利学術目的)C-0003.pdf
同意書(営利目的)C-0003p.pdf
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提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください（詳細）。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
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| 提供手数料 |
手数料とお支払いについてはこちらをご覧ください。 |
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細胞基本情報
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寄託者 |
Terasaki, Takeo
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| 樹立者 |
Terasaki, T. & Shimosato, Y.
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| 寄託日 |
1990
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| 動物種 |
_human
< Mammals
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| 属名 |
Homo
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| 種名 |
sapiens
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| 人種 |
Japanese
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| 性別 |
Male
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| 齢 |
80 years
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| 採取組織 |
lung
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| 病名 |
small cell carcinoma
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| 細胞分類 |
cancer
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| 初代培養日 |
1982
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|
細胞寿命 |
infinite
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| 細胞形態 |
other
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| Cellosaurus(Expasy) |
CVCL_1388
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細胞培養・検査情報
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寄託時情報 |
ロット情報 |
| 培地・試薬情報 |
培地・試薬一覧はこちらをご覧ください。 |
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培養形態 |
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Suspension cells
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| 培地 |
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RPMI1640 + 10% FBS
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| 培養方法 |
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浮遊細胞の培養に関する一般的な注意
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| 抗生物質 |
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Free
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継代方法 |
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dilution
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|
継代密度 |
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1 : 2 split
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| 継代・培地交換頻度 |
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Subculture : once/week, Medium Renewal : 2 times/week
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| 培養最適温度 |
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37
℃
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| 二酸化炭素濃度 |
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5
%
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| 凍結培地 |
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Medium + 10% DMSO
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| 凍結方法 |
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Slow freezing
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| マイコプラズマ |
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(-)
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| ウィルス（HIV) |
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(-)
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| アイソザイム検査 |
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LD, NP
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| 染色体検査 |
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48-93(50) : /61(5),62(5),63(6),64(9),65(9),66(2)/
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| 個体識別検査 |
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OK
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| 文献情報 |
Reference(英) |
11件
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| Reference(日) |
2件
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| 利用者成果(英) |
10件
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| 利用者成果(日) |
0件
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| Reference(英) |
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869
anaka K, Terasaki T.
Immunocytochemical expression of microtubule-associated protein-2 (MAP-2) in small cell lung cancer cell lines with neuronal-like processes
Jpn J Cancer Res
2002
93(6):699-705
PubMed ID: 12079519
DOI: 10.1111/j.1349-7006.2002.tb01309.x
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870
Yokoi S, Yasui K, Saito-Ohara F, Koshikawa K, Iizasa T, Fujisawa T, Terasaki T, Horii A, Takahashi T, Hirohashi S, Inazawa J.
A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers
Am J Pathol
2002
161(1):207-16
PubMed ID: 12107105
DOI: 10.1016/S0002-9440(10)64172-7
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3150
Tanaka K, Terasaki T
Development and elongation of neurite-like outgrowth on small cell lung cancer cell lines
Oncogene
1997
88:176-183
PubMed ID: 9119746
DOI: 10.1111/j.1349-7006.1997.tb00363.x
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3144
Shimoyama Y, Gotoh M, Terasaki T, Kitajima M, Hirohashi S
Isolation and sequence analysis of human cadherin-6 complementary DNA for the full coding sequence and its expression in human carcinoma cells.
Cancer Res
1995
55:2206-11
PubMed ID: 7743525
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1974
Terasaki T, Matsuno Y, Shimosato Y, Yamaguchi K, Ichinose H, Nagatsu T, Kato K
Establishment of a human small cell lung cancer cell line producing a large amount of anti-diuretic hormone.
Jpn J Cancer Res (--> Cancer Sci)
1994
85:718-22
PubMed ID: 8071114
DOI: 10.1111/j.1349-7006.1994.tb02420.x
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1368
Matsumoto T, Terasaki T, Mukai K, Wada M, Okamoto A, Yokota J, Yamaguchi K, Kato K, Nagatsu T, Shimosato Y
Relation between nucleolar size and growth characteristics in small cell lung cancer cell lines.
Jpn J Cancer Res
1991
82:820-8
PubMed ID: 1715338
DOI: 10.1111/j.1349-7006.1991.tb02708.x
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1320
Terasaki T, Shimosato Y, Wada M, Yokota J, Terada M
Selection of Radioresistant Cell by Vitamin A Deficiency in a Small Cell Lung Cancer Cell Line
Jpn J Cancer Res
1990
81:780-785
PubMed ID: 2168867
DOI: 10.1111/j.1349-7006.1990.tb02645.x
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3142
Nakagawa K, Yokota J, Wada M, Sasaki Y, Fujiwara Y, Sakai M, Muramatsu M, Terasaki T, Tsunokawa Y, Terada M, et al.
Levels of glutathione S transferase pi mRNA in human lung cancer cell lines correlate with the resistance to cisplatin and carboplatin.
Jpn J Cancer Res
1988
79:301-4
PubMed ID: 2836347
DOI: 10.1111/j.1349-7006.1988.tb01590.x
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1114
Terasaki T, Shimosato Y, Nakajima T, Tsumuraya M, Ichinose H, Nagatsu T, Kato K
Reversible squamous cell characteristics induced by vitamin A deficiency in a small cell lung cancer cell line.
Cancer Res
1987
47:3533-7
PubMed ID: 2438038
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1118
Terasaki T, Shimosato Y, Nakajima T, Tsumuraya M, Morinaga S, Hirohashi S, Yamaguchi K, Kato K, Ichinose H, Nagatsu T
Changes in cell characteristics due to culture conditions in cell lines from human small cell lung cancer.
Jpn J Clin Oncol
1986
16:203-12
PubMed ID: 3022030
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735
Terasaki T, Kameya T, Nakajima T, Tsumuraya M, Shimosato Y, Kato K, Ichinose H, Nagatsu T, Hasegawa T
Interconversion of biological characteristics of small cell lung cancer depending on culture conditions.
Gann
1984
75:1089-99
PubMed ID: 6098504
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| 利用者成果(英) |
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11097
Horie M, Miyashita N, Mattsson JSM, Mikami Y, Sandelin M, Brunnstrom H, Micke P, Nagase T, Saito A.
An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer.
J. Pathol.
2018
246(2):154-165
PubMed ID: 29876935
DOI: 10.1002/path.5109
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12942
Horie M, Saito A, Ohshima M, Suzuki HI, Nagase T.
YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer
Cancer Sci
2016
107(12):1755-1766
PubMed ID: 27627196
DOI: 10.1111/cas.13078
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18292
Walls M, Baxi SM, Mehta PP, Liu KK, Zhu J, Estrella H, Li C, Zientek M, Zong Q, Smeal T, Yin MJ.
Targeting small cell lung cancer harboring PIK3CA mutation with a selective oral PI3K inhibitor PF-4989216
Clin Cancer Res
2014
20(3):631-43
PubMed ID: 24240111
DOI: 10.1158/1078-0432.CCR-13-1663
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8174
Takezawa K, Okamoto I, Tsukioka S, Uchida J, Kiniwa M, Fukuoka M, Nakagawa K.
Identification of thymidylate synthase as a potential therapeutic target for lung cancer.
Br. J. Cancer
2010
103:354-61
PubMed ID: 20628382
DOI: 10.1038/sj.bjc.6605793
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6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
DOI: 10.1111/j.1749-0774.2009.00071.x
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3335
Yoshino K, Iimura E, Saijo K, Iwase S, Fukami K, Ohno T, Obata Y, Nakamura Y.
Essential role for gene profiling analysis in the authentication of human cell lines.
Hum Cell
2006
19(1):43-8
PubMed ID: 16643607
DOI: 10.1111/j.1749-0774.2005.00007.x
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3409
Sato, Masamitsu, Takahashi, Kenji, Nagayama, Kazuhiro, Arai, Yasuhito, Ito, Nobue, Okada, Mitsumasa, Minna, John D, Yokota, Jun, Kohno, Takashi
Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer.
Genes Chromosomes Cancer
2005
44:405-14
PubMed ID: 16114034
DOI: 10.1002/gcc.20253
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3094
Kaneda, Atsushi, Wakazono, Kuniko, Tsukamoto, Tetsuya, Watanabe, Naoko, Yagi, Yukiko, Tatematsu, Masae, Kaminishi, Michio, Sugimura, Takashi, Ushijima, Toshikazu
Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers.
Cancer Res
2004
64:6410-5
PubMed ID: 15374948
DOI: 10.1158/0008-5472.CAN-04-1543
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3140
Koh T, Yokota J, Ookawa K, Kina T, Koshimura K, Miwa S, Ariyasu T, Yamada H, Osaka M, Haga H, et al.
Alternative splicing of the neurofibromatosis 1 gene correlates with growth patterns and neuroendocrine properties of human small-cell lung-carcinoma cells.
Int J Cancer
1995
60:843-7
PubMed ID: 7896456
DOI: 10.1002/ijc.2910600620
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6407
Matsushima Y, Kinoshita Y, Nakata H, Inomoto-Naribayashi Y, Asahara M, Kawanami C, Nakamura A, Ito M, Matsui T, Fujiwara T, et al.
Gastrin receptor gene expression in several human carcinomas.
Jpn J Cancer Res
1994
85(8):819-24
PubMed ID: 7928627
DOI: 10.1111/j.1349-7006.1994.tb02953.x
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