Search
CELL BANK Website

Back Back
Cell No. : Cell Name
RCB0455 : LC-1/sq  update : 2022/10/13
CommentHuman cell line derived from lung cancer. Squamous cell carcinoma. The parental cell line of LC-1/sq-SF (RCB0438). LC-1/sq-SF (RCB0438), LC-1F (RCB0439), and LC-1/sq (RCB0455) are derived from the same patient.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Itoh, Hiroshi
Originator Kataoka, Hiroaki
Year of deposit 1989
Animal human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Male
Age at sampling 69 years
Tissue lung
Classification cancer
Year of origin 1986
History H. Kataoka
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_3008
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives (HamF12 : RPMI1640 = 1 : 1) + 25mM HEPES + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : once/1-2 weeks, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Virus (HIV) (-)
Isozyme LD, NP
Chromosome mode 82-467(50) : /94(3),95(7),96(7),97(2),98(2),99(4)/
STR(human) OK
Reference information Reference 1
User's Publication 15


To topTop
Reference
1779  Itoh H, Kataoka H, Koita H, Nabeshima K, Inoue T, Kangawa K, Koono M  Establishment of a new human cancer cell line secreting protease nexin-II/amyloid beta protein precursor derived from squamous-cell carcinoma of lung.  Int J Cancer  1991  49:436-43  PubMed ID: 1917142

To topTop
User's Publication
20884  Shindo A, Kusano M, Sakagami H, Amano S, Inomata M, Abe M, Okazawa M, Ooka T.  Comparison of UVC Sensitivity and Dectin-2 Expression Between Malignant and Non-malignant Cells.  In Vivo  2022  36(5):2116-2125  PubMed ID: 36099100
20104  Abe K, Kanehira M, Ohkouchi S, Kumata S, Suzuki Y, Oishi H, Noda M, Sakurada A, Miyauchi E, Fujiwara T, Harigae H, Okada Y.  Targeting stanniocalcin-1-expressing tumor cells elicits efficient antitumor effects in a mouse model of human lung cancer.  Cancer Med  2021    PubMed ID: 33826244
15500  Zhu LM, Shi HX, Sugimoto M, Bandow K, Sakagami H, Amano S, Deng HB, Ye QY, Gai Y, Xin XL, Xu ZY.  Feiyanning Formula Induces Apoptosis of Lung Adenocarcinoma Cells by Activating the Mitochondrial Pathway  Front Oncol   2021  11:690878  PubMed ID: 34277435
11379  Omoto K, Matsuda R, Nakai Y, Tatsumi Y, Nakazawa T, Tanaka Y, Shida Y, Murakami T, Nishimura F, Nakagawa I, Motoyama Y, Nakamura M, Fujimoto K, Hiroyuki N.  Expression of peptide transporter 1 has a positive correlation in protoporphyrin IX accumulation induced by 5-aminolevulinic acid with photodynamic detection of non-small cell lung cancer and metastatic brain tumor specimens originating from non-small cell lung cancer.  Photodiagnosis Photodyn Ther  2019    PubMed ID: 30639584
11511  Behan FM, Iorio F, Picco G, Gonçalves E, Beaver CM, Migliardi G, Santos R, Rao Y, Sassi F, Pinnelli M, Ansari R, Harper S, Jackson DA, McRae R, Pooley R, Wilkinson P, van der Meer D, Dow D, Buser-Doepner C, Bertotti A, Trusolino L, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ.  Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.  Nature  2019    PubMed ID: 30971826
9522  Nishijima N, Seike M, Soeno C, Chiba M, Miyanaga A, Noro R, Sugano T, Matsumoto M, Kubota K, Gemma A.  miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells.  Int. J. Oncol.  2016  48:937-44  PubMed ID: 26783187
9887  Ye X, Zhou Q, Matsumoto Y, Moriyama M, Kageyama S, Komatsu M, Satoh S, Tsuchida M, Saijo Y.  Inhibition of Glutaminolysis Inhibits Cell Growth via Down-regulating Mtorc1 Signaling in Lung Squamous Cell Carcinoma.  Anticancer Res.  2016  36:6021-6029  PubMed ID: 27793929
6410  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Is parainfluenza virus a threatening virus for human cancer cell lines?  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309
16489  Seike M, Kondo T, Fujii K, Okano T, Yamada T, Matsuno Y, Gemma A, Kudoh S, Hirohashi S.  Proteomic signatures for histological types of lung cancer  Proteomics  2005  5(11):2939-48  PubMed ID: 15996008
3028  Tajima K, Demachi A, Ito Y, Nishida K, Akatsuka Y, Tsujimura K, Kuwano H, Mitsudomi T, Takahashi T, Kuzushima K  Identification of an epitope from the epithelial cell adhesion molecule eliciting HLA-A*2402-restricted cytotoxic T-lymphocyte responses.  Tissue Antigens  2004  64:650-9  PubMed ID: 15546337
3113  Yoshimasu, Tatsuya, Sakurai, Teruhisa, Oura, Shoji, Hirai, Issei, Tanino, Hirokazu, Kokawa, Yozo, Naito, Yasuaki, Okamura, Yoshitaka, Ota, Ichiro, Tani, Naoyuki, Matsuura, Nariaki  Increased expression of integrin alpha3beta1 in highly brain metastatic subclone of a human non-small cell lung cancer cell line.  Cancer Sci  2004  95:142-8  PubMed ID: 14965364
3027  Tajima, Kouhei, Ito, Yoshinori, Demachi, Ayako, Nishida, Keiko, Akatsuka, Yoshiki, Tsujimura, Kunio, Hida, Toyoaki, Morishima, Yasuo, Kuwano, Hiroyuki, Mitsudomi, Tetsuya, Takahashi, Toshitada, Kuzushima, Kiyotaka  Interferon-gamma differentially regulates susceptibility of lung cancer cells to telomerase-specific cytotoxic T lymphocytes.  Int J Cancer  2004  110:403-12  PubMed ID: 15095306
3338  Seike, Masahiro, Kondo, Tadashi, Fujii, Kazuyasu, Yamada, Tesshi, Gemma, Akihiko, Kudoh, Shoji, Hirohashi, Setsuo  Proteomic signature of human cancer cells.  Proteomics  2004  4:2776-88  PubMed ID: 15352251
3094  Kaneda, Atsushi, Wakazono, Kuniko, Tsukamoto, Tetsuya, Watanabe, Naoko, Yagi, Yukiko, Tatematsu, Masae, Kaminishi, Michio, Sugimura, Takashi, Ushijima, Toshikazu  Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers.  Cancer Res  2004  64:6410-5  PubMed ID: 15374948
16491  Nakanishi H, Suda T, Katoh M, Watanabe A, Igishi T, Kodani M, Matsumoto S, Nakamoto M, Shigeoka Y, Okabe T, Oshimura M, Shimizu E.  Loss of imprinting of PEG1/MEST in lung cancer cell lines  Oncol Rep  2004  12(6):1273-8  PubMed ID: 15547750



Back Back Return Top Page