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Cell No. : Cell Name
RCB0444 : RERF-LC-AI  update : 2024/09/19
CommentJapanese lung squamous carcinoma.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Akiyama, Mitoshi
Originator Akiyama, Mitoshi
Year of deposit 1989
Another name AOI
Animal _human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Male
Tissue lung
Disease name squamous carcinoma
Classification cancer
Year of origin 1983
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_4402
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Culture medium MEM + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma/Acholeplasma (-)
Virus (HIV) (-)
Isozyme LD, NP
Chromosome mode 45-102(50) : /47(2),48(11),49(9),50(12),51(6),52(2)/
STR(human) OK
Images
deposit info
lot info
Reference information Reference 3
User's Publication 75


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Reference
2209  Teraoka S, Kyoizumi S, Seyama T, Yamakido M, Akiyama M  A Novel SCID Mouse Model for Studying Spontaneous Metastasis of Human Lung Cancer to Human Tissue  Jpn J Cancer Res  1995  86:419-423  PubMed ID: 7790314   DOI: 10.1111/j.1349-7006.1995.tb03073.x
2208  Teraoka, S., Kyoizumi, S., Seyama, T., Yamakido, M., and Akiyama, M.  SCID mice model for the in vivo study of human oncothetapy: Studies on the growth and metastasis of human lung cancer  Int J Oncol  1994  5:501-508  PubMed ID: 21559605  
1152  Kyoizumi S, Akiyama M, Kouno N, Kobuke K, Hakoda M, Jones, S L, Yamakido M  Monoclonal antibodies to human squamous cell carcinoma of the lung and their application to tumor diagnosis.  Cancer Res  1985  45:3274-81  PubMed ID: 4005855  

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User's Publication
19844  Tanaka Y, Nakai T, Suzuki A, Kagawa Y, Noritake O, Taki T, Hashimoto H, Sakai T, Shibata Y, Izumi H, Nosaki K, Udagawa H, Zenke Y, Matsumoto S, Yoh K, Miyazaki S, Sakamoto N, Sakashita S, Kojima M, Watanbe R, Tsuboi M, Goto K, Ishii G.  Clinicopathological significance of peritumoral alveolar macrophages in patients with resected early-stage lung squamous cell carcinoma  Cancer Immunol Immunother  2023  72(7):2205-2215  PubMed ID: 36862151   DOI: 10.1007/s00262-023-03393-8
16739  Hori K, Higashida S, Osaki T, Kawano T, Inaba H, Matsuura K, Iwasaki T.  Intracellular delivery and photothermal therapeutic effects of polyhistidine peptide-modified gold nanoparticles  J Biotechnol  2022  354:34-44  PubMed ID: 35724765   DOI: 10.1016/j.jbiotec.2022.06.006
13332  Hase H, Aoki M, Matsumoto K, Nakai S, Nagata T, Takeda A, Ueda K, Minami K, Kitae K, Jingushi K, Ueda Y, Yamamoto M, Furukawa T, Sato M, Tsujikawa K.  Cancer type‑SLCO1B3 promotes epithelial‑mesenchymal transition resulting in the tumour progression of non‑small cell lung cancer.  Oncol Rep  2021    PubMed ID: 33155667   DOI: 10.3892/or.2020.7839
14507  Okita Y, Zheng L, Kawanishi K, Miyoshi H, Yanagihara K, Kato M.  Polyvinyl alcohol scaffolds and supplementation support 3D and sphere culturing of human cancer cell lines by reducing apoptosis and promoting cellular proliferation  Genes Cells  2021  26(5):336-343  PubMed ID: 33638919   DOI: 10.1111/gtc.12843
14789  Chang A, Liu L, Ashby JM, Wu D, Chen Y, O'Neill SS, Huang S, Wang J, Wang G, Cheng D, Tan X, Petty WJ, Pasche BC, Xiang R, Zhang W, Sun P.  Recruitment of KMT2C/MLL3 to DNA Damage Sites Mediates DNA Damage Responses and Regulates PARP Inhibitor Sensitivity in Cancer  Cancer Res  2021  81(12):3358-3373  PubMed ID: 33853832   DOI: 10.1158/0008-5472.CAN-21-0688
15848  Okita R, Shimizu K, Nojima Y, Saisho S, Nakata M.  Tofacitinib overcomes an IFNγ-induced decrease in NK cell-mediated cytotoxicity via the regulation of immune-related molecules in LC-2/ad  Thorac Cancer  2021  12(6):775-782  PubMed ID: 33491334   DOI: 10.1111/1759-7714.13847
16119  Sanoyama I, Sakurai Y, Ichinoe M, Hoshino A, Kesen Y, Kato T, Numata Y, Umezawa A, Jiang SX, Murakumo Y.  Increased expression of REV7 in small cell lung carcinomas and its association with tumor cell survival and proliferation  Pathol Int  2021  71(1):15-23  PubMed ID: 33112501   DOI: 10.1111/pin.13040
16238  Mikac S, Rychłowski M, Dziadosz A, Szabelska-Beresewicz A, Fahraeus R, Hupp T, Sznarkowska A.  Identification of a Stable, Non-Canonically Regulated Nrf2 Form in Lung Cancer Cells  Antioxidants (Basel)   2021  10(5):786  PubMed ID: 34063559   DOI: 10.3390/antiox10050786
16801  Minegishi K, Dobashi Y, Tsubochi H, Hagiwara K, Ishibashi Y, Nomura S, Nakamura R, Ohmoto Y, Endo S.  TFF-1 Functions to Suppress Multiple Phenotypes Associated with Lung Cancer Progression  Onco Targets Ther  2021  14:4761-4777  PubMed ID: 34531663   DOI: 10.2147/OTT.S322697
12073  Haruna M, Hirata M, Iwahori K, Kanazawa T, Yamamoto Y, Goto K, Kawashima A, Morimoto-Okazawa A, Funaki S, Shintani Y, Kumanogoh A, Wada H.  Docetaxel Upregulates HMGB1 Levels in Non-small Cell Lung Cancer.  Biol. Pharm. Bull.  2020    PubMed ID: 32115500   DOI: 10.1248/bpb.b19-00702
13246  Bilguun EO, Kaira K, Kawabata-Iwakawa R, Rokudai S, Shimizu K, Yokobori T, Oyama T, Shirabe K, Nishiyama M.  Distinctive roles of syntaxin binding protein 4 and its action target, TP63, in lung squamous cell carcinoma: a theranostic study for the precision medicine.  BMC Cancer  2020    PubMed ID: 32993587   DOI: 10.1186/s12885-020-07448-2
13773  Saigusa D, Motoike IN, Saito S, Zorzi M, Aoki Y, Kitamura H, Suzuki M, Katsuoka F, Ishii H, Kinoshita K, Motohashi H, Yamamoto M.  Impacts of NRF2 activation in non-small-cell lung cancer cell lines on extracellular metabolites  Cancer Sci  2020  111(2):667-678  PubMed ID: 31828882   DOI: 10.1111/cas.14278
13429  Erkhem-Ochir Bilguunm, Kyoichi Kaira, Reika Kawabata-Iwakawa, Susumu Rokudai, Kimihiro Shimizu, Takehiko Yokobori, Tetsunari Oyama, Ken Shirabe, Masahiko Nishiyama  Syntaxin binding protein 4 as a novel therapeutic target and an effective biomarker for better treatment selection in lung squamous cell carcinoma: A theranostic study  BMC Cancer  2020      DOI: 10.21203/rs.3.rs-39783/v1
14834  Saito R, Miki Y, Abe T, Miyauchi E, Abe J, Nanamiya R, Inoue C, Sato I, Sasano H.  11β hydroxysteroid dehydrogenase 1: a new marker for predicting response to immune-checkpoint blockade therapy in non-small-cell lung carcinoma  Br J Cancer  2020  123(1):61-71  PubMed ID: 32336752   DOI: 10.1038/s41416-020-0837-3
11379  Omoto K, Matsuda R, Nakai Y, Tatsumi Y, Nakazawa T, Tanaka Y, Shida Y, Murakami T, Nishimura F, Nakagawa I, Motoyama Y, Nakamura M, Fujimoto K, Hiroyuki N.  Expression of peptide transporter 1 has a positive correlation in protoporphyrin IX accumulation induced by 5-aminolevulinic acid with photodynamic detection of non-small cell lung cancer and metastatic brain tumor specimens originating from non-small cell lung cancer.  Photodiagnosis Photodyn Ther  2019    PubMed ID: 30639584   DOI: 10.1016/j.pdpdt.2019.01.009
11496  Miyake N, Chikumi H, Yamaguchi K, Takata M, Takata M, Okada K, Kitaura T, Nakamoto M, Yamasaki A.  Effect of Cetuximab and EGFR Small Interfering RNA Combination Treatment in NSCLC Cell Lines with Wild Type EGFR and Use of KRAS as a Possible Biomarker for Treatment Responsiveness.  Yonago Acta Med  2019    PubMed ID: 30962749   DOI: 10.33160/yam.2019.03.012
11816  Maruhashi R, Eguchi H, Akizuki R, Hamada S, Furuta T, Matsunaga T, Endo S, Ichihara K, Ikari A.  Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells.  Sci Rep  2019    PubMed ID: 31551535   DOI: 10.1038/s41598-019-50276-z
14814  Hamanaka N, Nakanishi Y, Mizuno T, Horiguchi-Takei K, Akiyama N, Tanimura H, Hasegawa M, Satoh Y, Tachibana Y, Fujii T, Sakata K, Ogasawara K, Ebiike H, Koyano H, Sato H, Ishii N, Mio T.  YES1 Is a Targetable Oncogene in Cancers Harboring YES1 Gene Amplification  Cancer Res  2019  79(22):5734-5745  PubMed ID: 31391186   DOI: 10.1158/0008-5472.CAN-18-3376
10748  Matsumoto T, Nagashio R, Ryuge S, Igawa S, Kobayashi M, Fukuda E, Goshima N, Ichinoe M, Jiang SX, Satoh Y, Masuda N, Murakumo Y, Saegusa M, Sato Y.  Basigin expression as a prognostic indicator in stage I pulmonary adenocarcinoma.  Pathol. Int.  2018  68:232-240  PubMed ID: 29431238   DOI: 10.1111/pin.12646
10842  Yanagita K, Nagashio R, Jiang SX, Kuchitsu Y, Hachimura K, Ichinoe M, Igawa S, Fukuda E, Goshima N, Satoh Y, Murakumo Y, Saegusa M, Sato Y.  Cytoskeleton-Associated Protein 4 Is a Novel Serodiagnostic Marker for Lung Cancer.  Am. J. Pathol.  2018  188:1328-1333  PubMed ID: 29751934   DOI: 10.1016/j.ajpath.2018.03.007
11149  Shimizu K, Okita R, Saisho S, Maeda AI, Nojima Y, Nakata M.  Impact of COX2 Inhibitor for Regulation of PD-L1 Expression in Non-small Cell Lung Cancer.  Anticancer Res.  2018  38(8):4637-4644  PubMed ID: 30061230   DOI: 10.21873/anticanres.12768
14822  Hayashi T, Desmeules P, Smith RS, Drilon A, Somwar R, Ladanyi M.  RASA1 and NF1 are Preferentially Co-Mutated and Define A Distinct Genetic Subset of Smoking-Associated Non-Small Cell Lung Carcinomas Sensitive to MEK Inhibition  Clin Cancer Res  2018  24(6):1436-1447  PubMed ID: 29127119   DOI: 10.1158/1078-0432.CCR-17-2343
7006  Iida K, Sakai R, Yokoyama S, Kobayashi N, Togo S, Yoshikawa HY, Rawangkan A, Namiki K, Suganuma M.  Cell softening in malignant progression of human lung cancer cells by activation of receptor tyrosine kinase AXL.  Sci Rep  2017  7:17770  PubMed ID: 29259259   DOI: 10.1038/s41598-017-18120-4
9953  Akizuki R, Shimobaba S, Matsunaga T, Endo S, Ikari A.  Claudin-5, -7, and -18 suppress proliferation mediated by inhibition of phosphorylation of Akt in human lung squamous cell carcinoma.  Biochim. Biophys. Acta  2017  1864:293-302  PubMed ID: 27884700   DOI: 10.1016/j.bbamcr.2016.11.018
14238  Ozono K, Ohishi Y, Onishi H, Nakamura K, Motoshita J, Kato M, Nakanishi R, Nakamura M, Oda Y.  Brain-derived neurotrophic factor/tropomyosin-related kinase B signaling pathway contributes to the aggressive behavior of lung squamous cell carcinoma  Lab Invest  2017  97(11):1332-1342  PubMed ID: 28604655   DOI: 10.1038/labinvest.2017.45
14683  Ono C, Fukuhara T, Motooka D, Nakamura S, Okuzaki D, Yamamoto S, Tamura T, Mori H, Sato A, Uemura K, Fauzyah Y, Kurihara T, Suda T, Nishio A, Hmwe SS, Okamoto T, Tatsumi T, Takehara T, Chayama K, Wakita T, Koike K, Matsuura Y.  Characterization of miR-122-independent propagation of HCV  PLoS Pathog  2017  13(5):e1006374  PubMed ID: 28494029   DOI: 10.1371/journal.ppat.1006374
14717  Kuji S, Watanabe R, Sato Y, Iwata T, Hirashima Y, Takekuma M, Ito I, Abe M, Nagashio R, Omae K, Aoki D, Kameya T.  A new marker, insulinoma-associated protein 1 (INSM1), for high-grade neuroendocrine carcinoma of the uterine cervix: Analysis of 37 cases  Gynecol Oncol  2017  144(2):384-390.  PubMed ID: 27908529   DOI: 10.1016/j.ygyno.2016.11.020
9581  Shimobaba S, Taga S, Akizuki R, Hichino A, Endo S, Matsunaga T, Watanabe R, Yamaguchi M, Yamazaki Y, Sugatani J, Ikari A.  Claudin-18 inhibits cell proliferation and motility mediated by inhibition of phosphorylation of PDK1 and Akt in human lung adenocarcinoma A549 cells.  Biochim. Biophys. Acta  2016  1863:1170-8  PubMed ID: 26919807   DOI: 10.1016/j.bbamcr.2016.02.015
9887  Ye X, Zhou Q, Matsumoto Y, Moriyama M, Kageyama S, Komatsu M, Satoh S, Tsuchida M, Saijo Y.  Inhibition of Glutaminolysis Inhibits Cell Growth via Down-regulating Mtorc1 Signaling in Lung Squamous Cell Carcinoma.  Anticancer Res.  2016  36:6021-6029  PubMed ID: 27793929   DOI: 10.21873/anticanres.11191
12612  Yonesaka K, Hirotani K, Kawakami H, Takeda M, Kaneda H, Sakai K, Okamoto I, Nishio K, Jänne PA, Nakagawa K.  Anti-HER3 monoclonal antibody patritumab sensitizes refractory non-small cell lung cancer to the epidermal growth factor receptor inhibitor erlotinib  Oncogene  2016  35(7):878-86  PubMed ID: 25961915   DOI: 10.1038/onc.2015.142
14314  Okita R, Wolf D, Yasuda K, Maeda A, Yukawa T, Saisho S, Shimizu K, Yamaguchi Y, Oka M, Nakayama E, Lundqvist A, Kiessling R, Seliger B, Nakata M.  Contrasting Effects of the Cytotoxic Anticancer Drug Gemcitabine and the EGFR Tyrosine Kinase Inhibitor Gefitinib on NK Cell-Mediated Cytotoxicity via Regulation of NKG2D Ligand in Non-Small-Cell Lung Cancer Cells  PLoS One  2015  10(10):e0139809  PubMed ID: 26439264   DOI: 10.1371/journal.pone.0139809
15182  Saito K, Kobayashi M, Nagashio R, Ryuge S, Katono K, Nakashima H, Tsuchiya B, Jiang SX, Saegusa M, Satoh Y, Masuda N, Sato Y.  S100A16 is a Prognostic Marker for Lung Adenocarcinomas  Asian Pac J Cancer Prev  2015  16(16):7039-44  PubMed ID: 26514487   DOI: 10.7314/apjcp.2015.16.16.7039
15436  Kusakabe K, Ide N, Daigo Y, Itoh T, Yamamoto T, Kojima E, Mitsuoka Y, Tadano G, Tagashira S, Higashino K, Okano Y, Sato Y, Inoue M, Iguchi M, Kanazawa T, Ishioka Y, Dohi K, Kido Y, Sakamoto S, Ando S, Maeda M, Higaki M, Yoshizawa H, Murai H, Nakamura Y.  A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity  Bioorg Med Chem  2015  23(9):2247-60  PubMed ID: 25801152   DOI: 10.1016/j.bmc.2015.02.042
15907  Chen Z, Ye X, Tang N, Shen S, Li Z, Niu X, Lu S, Xu L.  The histone acetylranseferase hMOF acetylates Nrf2 and regulates anti-drug responses in human non-small cell lung cancer  Br J Pharmacol  2014  171(13):3196-211  PubMed ID: 24571482   DOI: 10.1111/bph.12661
18077  Shiho Sakuma, Eiko Otake, Kan Torii, Motoki Nakamura, Akira Maeda, Ryoto Tujii, Haruo Akashi, Hiromi Ohi, Shigenobu Yano, Akimichi Morita  Photodynamic therapy with glycoconjugated chlorin photosensitizer  Journal of Porphyrins and Phthalocyanines  2013  17:331-342    DOI: 10.1142/S1088424613500065
18278  Yamaguchi H, Kidachi Y, Kamiie K, Noshita T, Umetsu H, Fuke Y, Ryoyama K.  Utilization of 6-(methylsulfinyl)hexyl isothiocyanate for sensitization of tumor cells to antitumor agents in combination therapies  Biochem Pharmacol  2013  86(4):458-68  PubMed ID: 23791871   DOI: 10.1016/j.bcp.2013.06.008
13951  Oshita H, Nishino R, Takano A, Fujitomo T, Aragaki M, Kato T, Akiyama H, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y.  RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer  Mol Cancer Res  2013  11(8):937-51  PubMed ID: 23686708   DOI: 10.1158/1541-7786.MCR-12-0685-T
7627  Ohue Y, Eikawa S, Okazaki N, Mizote Y, Isobe M, Uenaka A, Fukuda M, Old LJ, Oka M, Nakayama E.  Spontaneous antibody, and CD4 and CD8 T-cell responses against XAGE-1b (GAGED2a) in non-small cell lung cancer patients.  Int. J. Cancer  2012  131:E649-58  PubMed ID: 22109656   DOI: 10.1002/ijc.27359
19226  Fukuhara T, Kambara H, Shiokawa M, Ono C, Katoh H, Morita E, Okuzaki D, Maehara Y, Koike K, Matsuura Y.  Expression of microRNA miR-122 facilitates an efficient replication in nonhepatic cells upon infection with hepatitis C virus  J Virol  2012  86(15):7918-33  PubMed ID: 22593164   DOI: 10.1128/JVI.00567-12
9094  Yumiko Shimura, Junya Suzuki, Miho Muraoka, Maria Carmelita Zulueta Kasuya, Koji Matsuoka, Kenichi Hatanaka  Large Scale Biosynthesis of Ganglioside Analogues by RERF-LC-AI Cells Cultured in HYPERFlask  Prep Biochem Biotechnol  2012  42 (4), 378-92  PubMed ID: 22708814   DOI: 10.1080/10826068.2011.627971
12718  Ikari A, Sato T, Watanabe R, Yamazaki Y, Sugatani J.  Increase in claudin-2 expression by an EGFR/MEK/ERK/c-Fos pathway in lung adenocarcinoma A549 cells  Biochim Biophys Acta  2012  1823(6):1110-8  PubMed ID: 22546605   DOI: 10.1016/j.bbamcr.2012.04.005
13664  Ohgidani M, Ichihara H, Goto K, Matsumoto Y, Ueoka R.  Anticancer effects of residual powder from Barley-Shochu distillation remnants against the orthotopic xenograft mouse models of hepatocellular carcinoma in vivo  Biol Pharm Bull  2012  35(6):984-7  PubMed ID: 22687544   DOI: 10.1248/bpb.35.984
14287  Kobayashi M, Matsumoto T, Ryuge S, Yanagita K, Nagashio R, Kawakami Y, Goshima N, Jiang SX, Saegusa M, Iyoda A, Satoh Y, Masuda N, Sato Y.  CAXII Is a sero-diagnostic marker for lung cancer  PLoS One  2012  7(3):e33952  PubMed ID: 22439015   DOI: 10.1371/journal.pone.0033952
14406  Miyake N, Chikumi H, Takata M, Nakamoto M, Igishi T, Shimizu E.  Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells  Oncol Rep  2012  28(3):848-54  PubMed ID: 22710790   DOI: 10.3892/or.2012.1855
17472  Ashinuma H, Takiguchi Y, Kitazono S, Kitazono-Saitoh M, Kitamura A, Chiba T, Tada Y, Kurosu K, Sakaida E, Sekine I, Tanabe N, Iwama A, Yokosuka O, Tatsumi K.  Antiproliferative action of metformin in human lung cancer cell lines  Oncol Rep  2012  28(1):8-14  PubMed ID: 22576795   DOI: 10.3892/or.2012.1763
16552  Tasaki M, Shimada K, Kimura H, Tsujikawa K, Konishi N.  ALKBH3, a human AlkB homologue, contributes to cell survival in human non-small-cell lung cancer  Br J Cancer  2011  104(4):700-6  PubMed ID: 21285982   DOI: 10.1038/sj.bjc.6606012
16553  Hayashi S, Kumai T, Matsuda Y, Aoki N, Sato K, Kimura S, Kitada M, Tateno M, Celis E, Kobayashi H.  Six-transmembrane epithelial antigen of the prostate and enhancer of zeste homolog 2 as immunotherapeutic targets for lung cancer  J Transl Med  2011  9:191  PubMed ID: 22053850   DOI: 10.1186/1479-5876-9-191
5870  Takahashi N, Fukushima T, Yorita K, Tanaka H, Chijiiwa K, Kataoka H.  Dickkopf-1 is overexpressed in human pancreatic ductal adenocarcinoma cells and is involved in invasive growth.  Int J Cancer.  2010  126(7):1611-20  PubMed ID: 19711349   DOI: 10.1002/ijc.24865
18295  Homma S, Ishii Y, Morishima Y, Yamadori T, Matsuno Y, Haraguchi N, Kikuchi N, Satoh H, Sakamoto T, Hizawa N, Itoh K, Yamamoto M.  Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer  Clin Cancer Res  2009  15(10):3423-32  PubMed ID: 19417020   DOI: 10.1158/1078-0432.CCR-08-2822
5877  Yamamoto H, Okumura K, Toshima S, Mukaisho K, Sugihara H, Hattori T, Kato M, Asano S.  FXYD3 protein involved in tumor cell proliferation is overproduced in human breast cancer tissues.  Biol Pharm Bull  2009  32(7):1148-54  PubMed ID: 19571376   DOI: 10.1248/bpb.32.1148
6410  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Is parainfluenza virus a threatening virus for human cancer cell lines?  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309   DOI: 10.1111/j.1749-0774.2009.00071.x
18307  Moriya S, Takiguchi M, Seki N.  Expression of the WT1 gene -KTS domain isoforms suppresses the invasive ability of human lung squamous cell carcinoma cells  Int J Oncol  2008  32(2):349-56  PubMed ID: 18202757  
18890  Nagashio R, Sato Y, Jiang SX, Ryuge S, Kodera Y, Maeda T, Nakajima T.  Detection of tumor-specific autoantibodies in sera of patients with lung cancer  Lung Cancer  2008  62(3):364-73  PubMed ID: 18485524   DOI: 10.1016/j.lungcan.2008.03.026
5888  Kuwabara Y, Yamada T, Yamazaki K, Du WL, Banno K, Aoki D, Sakamoto M.  Establishment of an ovarian metastasis model and possible involvement of E-cadherin down-regulation in the metastasis.  Cancer Sci  2008  99(10):1933-9  PubMed ID: 19016752   DOI: 10.1111/j.1349-7006.2008.00946.x
15561  Kouta Funamoto, Yuji Komizu, Hideaki Ichihara, Osamu Tanoue, Koichi Goto, Ryuichi Ueoka  Antitumor and Immunostimulatory Effects of Residual Powder from Barley-Shochu Distillation Remnants  Journal of Health Science  2008  54:287-293    DOI: 10.1248/jhs.54.287
19222  Noro R, Gemma A, Miyanaga A, Kosaihira S, Minegishi Y, Nara M, Kokubo Y, Seike M, Kataoka K, Matsuda K, Okano T, Yoshimura A, Kudoh S.  PTEN inactivation in lung cancer cells and the effect of its recovery on treatment with epidermal growth factor receptor tyrosine kinase inhibitors  Int J Oncol  2007  31(5):1157-63  PubMed ID: 17912443  
6291  Asaka-Amano Y, Takiguchi Y, Yatomi M, Kurosu K, Kasahara Y, Tanabe N, Tatsumi K, Kuriyama T.  Effect of treatment schedule on the interaction of Cisplatin and radiation in human lung cancer cells.  Radiat Res  2007  167(6):637-44  PubMed ID: 17523845   DOI: 10.1667/RR0739.1
17469  Takiguchi Y, Miyamoto T, Nagao K, Kuriyama T.  Assessment of the homogeneous efficacy of carbon ions in the spread-out Bragg peak for human lung cancer cell lines  Radiat Med  2007  25(6):272-7  PubMed ID: 17634880   DOI: 10.1007/s11604-007-0134-6
3335  Yoshino K, Iimura E, Saijo K, Iwase S, Fukami K, Ohno T, Obata Y, Nakamura Y.  Essential role for gene profiling analysis in the authentication of human cell lines.  Hum Cell  2006  19(1):43-8  PubMed ID: 16643607   DOI: 10.1111/j.1749-0774.2005.00007.x
3061  Nagai, Yoshiaki, Miyazawa, Hitoshi, Tanaka, Tomoaki, Udagawa, Kiyoshi, Kato, Motoyasu, Fukuyama, Shunichiro, Yokote, Akemi, Kobayashi, Kunihiko, Kanazawa, Minoru, Hagiwara, Koichi, Hagiwara K  Genetic heterogeneity of the epidermal growth factor receptor in non-small cell lung cancer cell lines revealed by a rapid and sensitive detection system, the peptide nucleic acid-locked nucleic acid PCR clamp.  Cancer Res  2005  65:7276-82  PubMed ID: 16105816   DOI: 10.1158/0008-5472.CAN-05-0331
16489  Seike M, Kondo T, Fujii K, Okano T, Yamada T, Matsuno Y, Gemma A, Kudoh S, Hirohashi S.  Proteomic signatures for histological types of lung cancer  Proteomics  2005  5(11):2939-48  PubMed ID: 15996008   DOI: 10.1002/pmic.200401166
3107  Hashimoto, Kiyoshi, Araki, Kunio, Osaki, Mitsuhiko, Nakamura, Hiroshige, Tomita, Katsuyuki, Shimizu, Eiji, Ito, Hisao  MCM2 and Ki-67 expression in human lung adenocarcinoma: prognostic implications.  Pathobiology  2004  71:193-200  PubMed ID: 15263808   DOI: 10.1159/000078673
3338  Seike, Masahiro, Kondo, Tadashi, Fujii, Kazuyasu, Yamada, Tesshi, Gemma, Akihiko, Kudoh, Shoji, Hirohashi, Setsuo  Proteomic signature of human cancer cells.  Proteomics  2004  4:2776-88  PubMed ID: 15352251   DOI: 10.1002/pmic.200300795
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