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Cell No. : Cell Name
RCB0443 : TC-YIK  update : 2022/07/07
CommentIntegrating HPV16, neurosecretory granules(+)
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Ichimura, Hiroshi
Originator Ichimura, Hiroshi
Year of deposit 1989
Animal human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Female
Age at sampling 31 years
Tissue cervix
Disease name argyrophyl small-cell carcinom
Metastastatic ability Yes
Metastatsd tissue brain
Classification cancer
Year of origin 1989
Lifespan infinite
Morphology lymphocyte-like
Cellosaurus(Expasy) CVCL_1737
deposit info
lot info
Medium Medium List
Culture type Suspension cells
Medium and additives RPMI1640 + 10% FBS
Antibiotics Free
Passage method dilution
Culture information Passage ratio 1 : 4 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Virus (HIV) (-)
Isozyme LD, NP
Chromosome mode 40-57(50) : 46(3),47(4),48(6),49(4),50(14),51(10)/
STR(human) OK
Reference information Reference 1
User's Publication 3

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1151  Ichimura H, Yamasaki M, Yamane T, Shimizu H, Katsumoto T, Kurimura O, Kurimura T  Heterotransplantation of Argyrophil Small Cell Carcinoma of the Uterine Cervix Integrating HPV16 DNA into Nude Mice  Jpn J Cancer Res  1988  79:1255-1258  PubMed ID: 2853149   DOI: 10.1111/j.1349-7006.1988.tb01552.x

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User's Publication
4354  Egawa-Takata T, Yoshino K, Hiramatsu K, Nakagawa S, Serada S, Nakajima A, Endo H, Kubota S, Matsuzaki S, Kobayashi E, Ueda Y, Morii E, Inoue M, Naka T, Kimura T.  Small Cell Carcinomas of the Uterine Cervix and Lung: Proteomics Reveals Similar Protein Expression Profiles.  Int. J. Gynecol. Cancer  2018  28(9):1751-1757  PubMed ID: 30358701   DOI: 10.1097/IGC.0000000000001354
15200  Lizio M, Ishizu Y, Itoh M, Lassmann T, Hasegawa A, Kubosaki A, Severin J, Kawaji H, Nakamura Y, FANTOM consortium, Suzuki H, Hayashizaki Y, Carninci P, Forrest AR.  Mapping Mammalian Cell-type-specific Transcriptional Regulatory Networks Using KD-CAGE and ChIP-seq Data in the TC-YIK Cell Line  Front Genet  2015  6:331  PubMed ID: 26635867   DOI: 10.3389/fgene.2015.00331
6410  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Is parainfluenza virus a threatening virus for human cancer cell lines?  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309   DOI: 10.1111/j.1749-0774.2009.00071.x

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