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Cell No. : Cell Name
RCB0443 : TC-YIK  update : 2024/01/17
CommentIntegrating HPV16, neurosecretory granules(+)
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Ichimura, Hiroshi
Originator Ichimura, Hiroshi
Year of deposit 1989
Animal _human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Female
Age at sampling 31 years
Tissue cervix
Disease name argyrophyl small-cell carcinom
Metastatic ability Yes
Metastatic tissue brain
Classification cancer
Year of origin 1989
Lifespan infinite
Morphology lymphocyte-like
Cellosaurus(Expasy) CVCL_1737
deposit info
lot info
Medium Medium List
Culture type Suspension cells
Culture method 浮遊細胞の培養に関する一般的な注意(Japanese)
Culture medium RPMI1640 + 10% FBS
Antibiotics Free
Passage method dilution
Culture information Passage ratio 1 : 4 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Virus (HIV) (-)
Isozyme LD, NP
Chromosome mode 40-57(50) : 46(3),47(4),48(6),49(4),50(14),51(10)/
STR(human) OK
Reference information Reference 5
User's Publication 4


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Reference
198  Ichimura H, Sakashita N, Iida T, Chisaka T, Yasuda H, Kita M, Yuasa S, Imanishi J.  Differentiation of a cell line of human cervical argyrophil small cell carcinoma to macrophage lineage cells  Jpn J Cancer Res  1999  90(5):523-9  PubMed ID: 10391092   DOI: 10.1111/j.1349-7006.1999.tb00779.x
200  Shimizu H, Sawada M, Tohyama M, Takemura K, Akedo H, Ichimura H, Ueda G, Tanizawa O.  Effect of dibutyryl cyclic AMP on morphologic features and marker production of human cervical argyrophil small-cell carcinoma cell line  Int J Cancer  1994  56(5):766-71  PubMed ID: 8314356   DOI: 10.1002/ijc.2910560526
197  Ichimura H, Yamasaki M, Tamura I, Katsumoto T, Sawada M, Kurimura O, Furuyama J, Kurimura T.  Establishment and characterization of a new cell line TC-YIK originating from argyrophil small cell carcinoma of the uterine cervix integrating HPV16 DNA  Cancer  1991  67(9):2327-32  PubMed ID: 1849445   DOI: 10.1002/1097-0142(19910501)67:9<2327::aid-cncr2820670919>3.0.co;2-f
199  Hori T, Ichimura H, Minamihisamatsu M, Takahashi E, Yamauchi M, Hama Y, Kurimura O, Yamasaki M, Kurimura T.  Chromosomal insertion and amplification of human papillomavirus 16 DNA sequences in a cell line of argyrophil small cell carcinoma of the uterine cervix  Jpn J Cancer Res  1991  82(4):371-5  PubMed ID: 1646197   DOI: 10.1111/j.1349-7006.1991.tb01857.x
1151  Ichimura H, Yamasaki M, Yamane T, Shimizu H, Katsumoto T, Kurimura O, Kurimura T  Heterotransplantation of Argyrophil Small Cell Carcinoma of the Uterine Cervix Integrating HPV16 DNA into Nude Mice  Jpn J Cancer Res  1988  79:1255-1258  PubMed ID: 2853149   DOI: 10.1111/j.1349-7006.1988.tb01552.x

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User's Publication
17514  Kuji S, Endo A, Kubota M, Uekawa A, Kawakami F, Mikami Y, Koike J, Suzuki N.   Immunosensitivity and specificity of insulinoma-associated protein 1 (INSM1) for neuroendocrine neoplasms of the uterine cervix  J Gynecol Oncol  2023  4(1):e1  PubMed ID: 36245222   DOI: 10.3802/jgo.2023.34.e1
4354  Egawa-Takata T, Yoshino K, Hiramatsu K, Nakagawa S, Serada S, Nakajima A, Endo H, Kubota S, Matsuzaki S, Kobayashi E, Ueda Y, Morii E, Inoue M, Naka T, Kimura T.  Small Cell Carcinomas of the Uterine Cervix and Lung: Proteomics Reveals Similar Protein Expression Profiles.  Int. J. Gynecol. Cancer  2018  28(9):1751-1757  PubMed ID: 30358701   DOI: 10.1097/IGC.0000000000001354
15200  Lizio M, Ishizu Y, Itoh M, Lassmann T, Hasegawa A, Kubosaki A, Severin J, Kawaji H, Nakamura Y, FANTOM consortium, Suzuki H, Hayashizaki Y, Carninci P, Forrest AR.  Mapping Mammalian Cell-type-specific Transcriptional Regulatory Networks Using KD-CAGE and ChIP-seq Data in the TC-YIK Cell Line  Front Genet  2015  6:331  PubMed ID: 26635867   DOI: 10.3389/fgene.2015.00331
6410  Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.  Is parainfluenza virus a threatening virus for human cancer cell lines?  Hum Cell  2009  22(3):81-4  PubMed ID: 19624309   DOI: 10.1111/j.1749-0774.2009.00071.x



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