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								Shiba-Ishii A, Isagawa T, Shiozawa T, Mato N, Nakagawa T, Takada Y, Hirai K, Hong J, Saitoh A, Takeda N, Niki T, Murakami Y, Matsubara D. 
								Novel therapeutic strategies targeting bypass pathways and mitochondrial dysfunction to combat resistance to RET inhibitors in NSCLC. 
								Biochim Biophys Acta Mol Basis Dis 
								2024 
								167249 
								
									
										PubMed ID: 38768929
									
								 
								
									
										DOI: 10.1016/j.bbadis.2024.167249 | 
						
							
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								Kasai F, Fukushima M, Miyagi Y, Nakamura Y. 
								Genetic diversity among the present Japanese population: evidence from genotyping of human cell lines established in Japan 
								Hum Cell 
								2024 
								37(4):944-950 
								
									
										PubMed ID: 38639832
									
								 
								
									
										DOI: 10.1007/s13577-024-01055-0 | 
						
							
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								Miyazaki I, Odintsov I, Ishida K, Lui AJW, Kato M, Suzuki T, Zhang T, Wakayama K, Kurth RI, Cheng R, Fujita H, Delasos L, Vojnic M, Khodos I, Yamada Y, Ishizawa K, Mattar MS, Funabashi K, Chang Q, Ohkubo S, Yano W, Terada R, Giuliano C, Lu YC, Bonifacio A, Kunte S, Davare MA, Cheng EH, de Stanchina E, Lovati E, Iwasawa Y, Ladanyi M, Somwar R. 
								Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations. 
								Nat Cancer 
								2023 
								4(9):1345-1361 
								
									
										PubMed ID: 37743366
									
								 
								
									
										DOI: 10.1038/s43018-023-00630-y | 
						
							
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								Hirai S, Idogawa M, Sumi T, Yamaguchi M, Niki T, Sakuma Y. 
								Dual inhibition of BCL2L1 and MCL1 is highly effective against RET fusion-positive or MET exon 14 skipping mutation-positive lung adenocarcinoma cells 
								Biochem Biophys Res Commun  
								2022 
								630:24-29 
								
									
										PubMed ID: 36126466
									
								 
								
									
										DOI: 10.1016/j.bbrc.2022.09.039 | 
						
							
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								Suphakhong K, Terashima M, Wanna-Udom S, Takatsuka R, Ishimura A, Takino T, Suzuki T. 
								m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial-mesenchymal transition of lung cancer cells. 
								J Biol Chem 
								2022 
								298(11):102554 
								
									
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										DOI: 10.1016/j.jbc.2022.102554 | 
						
							
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								Kooijman JJ, van Riel WE, Dylus J, Prinsen MBW, Grobben Y, de Bitter TJJ, van Doornmalen AM, Melis JJTM, Uitdehaag JCM, Narumi Y, Kawase Y, de Roos JADM, Willemsen-Seegers N, Zaman GJR. 
								Comparative kinase and cancer cell panel profiling of kinase inhibitors approved for clinical use from 2018 to 2020 
								Front Oncol 
								2022 
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								Hase H, Aoki M, Matsumoto K, Nakai S, Nagata T, Takeda A, Ueda K, Minami K, Kitae K, Jingushi K, Ueda Y, Yamamoto M, Furukawa T, Sato M, Tsujikawa K. 
								Cancer type‑SLCO1B3 promotes epithelial‑mesenchymal transition resulting in the tumour progression of non‑small cell lung cancer. 
								Oncol Rep 
								2021 
								 
								
									
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								Abe K, Kanehira M, Ohkouchi S, Kumata S, Suzuki Y, Oishi H, Noda M, Sakurada A, Miyauchi E, Fujiwara T, Harigae H, Okada Y. 
								Targeting stanniocalcin-1-expressing tumor cells elicits efficient antitumor effects in a mouse model of human lung cancer. 
								Cancer Med 
								2021 
								 
								
									
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										DOI: 10.1002/cam4.3852 | 
						
							
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								Nakasone S, Suzuki A, Okazaki H, Onodera K, Zenkoh J, Ishii G, Suzuki Y, Tsuboi M, Tsuchihara K. 
								Predictive markers based on transcriptome modules for vinorelbine-based adjuvant chemotherapy for lung adenocarcinoma patients. 
								Lung Cancer 
								2021 
								158:115-125 
								
									
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										DOI: 10.1016/j.lungcan.2021.06.011 | 
						
							
							| 12021 
								Wanna-Udom S, Terashima M, Lyu H, Ishimura A, Takino T, Sakari M, Tsukahara T, Suzuki T. 
								The m6A methyltransferase METTL3 contributes to Transforming Growth Factor-beta-induced epithelial-mesenchymal transition of lung cancer cells through the regulation of JUNB. 
								Biochem. Biophys. Res. Commun. 
								2020 
								 
								
									
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								Kuchitsu Y, Nagashio R, Igawa S, Kusuhara S, Tsuchiya B, Ichinoe M, Satoh Y, Naoki K, Murakumo Y, Saegusa M, Sato Y. 
								TRAP1 is a predictive biomarker of platinum-based adjuvant chemotherapy benefits in patients with resected lung adenocarcinoma. 
								Biomed. Res. 
								2020 
								 
								
									
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								Fujimura T, Furugaki K, Harada N, Yoshimura Y. 
								Enhanced antitumor effect of alectinib in combination with cyclin-dependent kinase 4/6 inhibitor against RET-fusion-positive non-small cell lung cancer cells 
								Cancer Biol Ther 
								2020 
								21(9):863-870 
								
									
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										DOI: 10.1080/15384047.2020.1806643 | 
						
							
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								Saito S, Kitamura-Muramatsu Y, Komine F, Polat M, Takeshima SN, Takei M, Aida Y. 
								Absence of bovine leukemia virus proviral DNA in Japanese human blood cell lines and human cancer cell lines 
								Arch Virol 
								2020 
								165(1):207-214 
								
									
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								Hiyoshi Y, Sato Y, Ichinoe M, Nagashio R, Hagiuda D, Kobayashi M, Kusuhara S, Igawa S, Shiomi K, Goshima N, Murakumo Y, Saegusa M, Satoh Y, Masuda N, Naoki K. 
								Prognostic significance of IMMT expression in surgically-resected lung adenocarcinoma. 
								Thorac Cancer 
								2019 
								 
								
									
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								Koh Furugaki, Marie Mochizuki, Mirei Kohno, Sei Shu, Naoki Harada, Yasushi Yoshimura  
								Expression of C-terminal ALK, RET, or ROS1 in lung cancer cells with or without fusion 
								BMC Cancer 
								2019 
								19(1):301 
								
									
										PubMed ID: 30943926
									
								 
								
									
										DOI: 10.1186/s12885-019-5527-2 | 
						
							
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								Hagiuda D, Nagashio R, Ichinoe M, Tsuchiya B, Igawa S, Naoki K, Satoh Y, Murakumo Y, Saegusa M, Sato Y. 
								Clinicopathological and prognostic significance of nuclear UGDH localization in lung adenocarcinoma 
								Biomed Res 
								2019 
								40(1):17-27 
								
									
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								Shimizu K, Okita R, Saisho S, Maeda AI, Nojima Y, Nakata M. 
								Impact of COX2 Inhibitor for Regulation of PD-L1 Expression in Non-small Cell Lung Cancer. 
								Anticancer Res. 
								2018 
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								Terashima M, Ishimura A, Wanna-Udom S, Suzuki T. 
								MEG8 long noncoding RNA contributes to epigenetic progression of the epithelial-mesenchymal transition of lung and pancreatic cancer cells. 
								J. Biol. Chem. 
								2018 
								 
								
									
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								Ohara K, Ohkuri T, Kumai T, Nagato T, Nozaki Y, Ishibashi K, Kosaka A, Nagata M, Harabuchi S, Ohara M, Oikawa K, Aoki N, Harabuchi Y, Celis E, Kobayashi H. 
								Targeting phosphorylated p53 to elicit tumor-reactive T helper responses against head and neck squamous cell carcinoma. 
								Oncoimmunology 
								2018 
								 
								
									
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								Chang H, Sung JH, Moon SU, Kim HS, Kim JW, Lee JS. 
								EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells. 
								Yonsei Med. J. 
								2017 
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										DOI: 10.3349/ymj.2017.58.1.9 | 
						
							
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								Terashima M, Tange S, Ishimura A, Suzuki T. 
								MEG3 Long Noncoding RNA Contributes to the Epigenetic Regulation of Epithelial-Mesenchymal Transition in Lung Cancer Cell Lines. 
								J. Biol. Chem. 
								2017 
								292:82-99 
								
									
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								Seike M, Kim CH, Zou F, Noro R, Chiba M, Ishikawa A, Κunugi S, Kubota K, Gemma A. 
								AXL and GAS6 co-expression in lung adenocarcinoma as a prognostic classifier. 
								Oncol. Rep. 
								2017 
								37:3261-3269 
								
									
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								Terashima M, Ishimura A, Wanna-Udom S, Suzuki T. 
								Epigenetic regulation of epithelial-mesenchymal transition by KDM6A histone demethylase in lung cancer cells. 
								Biochem. Biophys. Res. Commun. 
								2017 
								490:1407-1413 
								
									
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								Reeser JW, Martin D, Miya J, Kautto EA, Lyon E, Zhu E, Wing MR, Smith A, Reeder M, Samorodnitsky E, Parks H, Naik KR, Gozgit J, Nowacki N, Davies KD, Varella-Garcia M, Yu L, Freud AG, Coleman J, Aisner DL, Roychowdhury S. 
								Validation of a Targeted RNA Sequencing Assay for Kinase Fusion Detection in Solid Tumors. 
								J Mol Diagn 
								2017 
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								Shigeaki Umeda et al 
								Loss of IL-24 expression facilitates invasion in lung adenocarcinoma  
								Int J Clin Exp Pathol 
								2017 
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								Horie M, Kaczkowski B, Ohshima M, Matsuzaki H, Noguchi S, Mikami Y, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest ARR, Takai D, Yamaguchi Y, Micke P, Saito A, Nagase T. 
								Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC 
								Mol Cancer Res 
								2017 
								15(10):1354-1365 
								
									
										PubMed ID: 28698358
									
								 
								
									
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								Yasunaga M, Manabe S, Matsumura Y. 
								Immunoregulation by IL-7R-targeting antibody-drug conjugates: overcoming steroid-resistance in cancer and autoimmune disease 
								Sci Rep 
								2017 
								7(1):10735 
								
									
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								Okita R, Maeda A, Shimizu K, Nojima Y, Saisho S, Nakata M. 
								PD-L1 overexpression is partially regulated by EGFR/HER2 signaling and associated with poor prognosis in patients with non-small-cell lung cancer 
								Cancer Immunol Immunother  
								2017 
								66(7):865-876 
								
									
										PubMed ID: 28341875
									
								 
								
									
										DOI: 10.1007/s00262-017-1986-y | 
						
							
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								Nishijima N, Seike M, Soeno C, Chiba M, Miyanaga A, Noro R, Sugano T, Matsumoto M, Kubota K, Gemma A. 
								miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells. 
								Int. J. Oncol. 
								2016 
								48:937-44 
								
									
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										DOI: 10.3892/ijo.2016.3331 | 
						
							
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								Okita R, Yukawa T, Nojima Y, Maeda A, Saisho S, Shimizu K, Nakata M. 
								MHC class I chain-related molecule A and B expression is upregulated by cisplatin and associated with good prognosis in patients with non-small cell lung cancer 
								Cancer Immunol Immunother 
								2016 
								65(5):499-509. 
								
									
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										DOI: 10.1007/s00262-016-1814-9 | 
						
							
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								Ito T, Matsubara D, Tanaka I, Makiya K, Tanei ZI, Kumagai Y, Shiu SJ, Nakaoka HJ, Ishikawa S, Isagawa T, Morikawa T, Shinozaki-Ushiku A, Goto Y, Nakano T, Tsuchiya T, Tsubochi H, Komura D, Aburatani H, Dobashi Y, Nakajima J, Endo S, Fukayama M, Sekido Y, Niki T, Murakami Y. 
								Loss of YAP1 defines neuroendocrine differentiation of lung tumors 
								Cancer Sci 
								2016 
								107(10):1527-1538 
								
									
										PubMed ID: 27418196
									
								 
								
									
										DOI: 10.1111/cas.13013 | 
						
							
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								Paweletz CP, Sacher AG, Raymond CK, Alden RS, O'Connell A, Mach SL, Kuang Y, Gandhi L, Kirschmeier P, English JM, Lim LP, Jänne PA, Oxnard GR. 
								Bias-Corrected Targeted Next-Generation Sequencing for Rapid, Multiplexed Detection of Actionable Alterations in Cell-Free DNA from Advanced Lung Cancer Patients 
								Clin Cancer Res 
								2016 
								22(4):915-22 
								
									
										PubMed ID: 26459174
									
								 
								
									
										DOI: 10.1158/1078-0432.CCR-15-1627-T | 
						
							
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								Okudela K, Mitsui H, Woo T, Kojima Y, Matsumura M, Arai H, Suzuki T, Umeda S, Tateishi Y, Saito Y, Tajiri M, Masuda M, Kameda Y, Ohashi K. 
								Expression of tropomyosins in lung cancer - a potential role in carcinogenesis and its utility in a histopathological diagnosis 
								Histol Histopathol 
								2016 
								31(8):857-66 
								
									
										PubMed ID: 26750107
									
								 
								
									
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								Liu G, Wu Q, Liu G, Song X, Zhang J. 
								Psoriasin (S100A7) is a novel biomarker for lung squamous cell carcinoma in humans. 
								Cancer Cell Int. 
								2015 
								15:18 
								
									
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										DOI: 10.1186/s12935-014-0154-0 | 
						
							
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								Katono K, Sato Y, Jiang SX, Kobayashi M, Nagashio R, Ryuge S, Fukuda E, Goshima N, Satoh Y, Saegusa M, Masuda N. 
								Prognostic significance of MYH9 expression in resected non-small cell lung cancer 
								PLoS One 
								2015 
								10(3):e0121460 
								
									
										PubMed ID: 25826333
									
								 
								
									
										DOI: 10.1371/journal.pone.0121460 | 
						
							
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								Okita R, Wolf D, Yasuda K, Maeda A, Yukawa T, Saisho S, Shimizu K, Yamaguchi Y, Oka M, Nakayama E, Lundqvist A, Kiessling R, Seliger B, Nakata M. 
								Contrasting Effects of the Cytotoxic Anticancer Drug Gemcitabine and the EGFR Tyrosine Kinase Inhibitor Gefitinib on NK Cell-Mediated Cytotoxicity via Regulation of NKG2D Ligand in Non-Small-Cell Lung Cancer Cells 
								PLoS One 
								2015 
								10(10):e0139809 
								
									
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										DOI: 10.1371/journal.pone.0139809 | 
						
							
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								Suzuki A, Matsushima K, Makinoshima H, Sugano S, Kohno T, Tsuchihara K, Suzuki Y. 
								Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment 
								Genome Biol 
								2015 
								16(1):66 
								
									
										PubMed ID: 25887790
									
								 
								
									
										DOI: 10.1186/s13059-015-0636-y | 
						
							
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								Sugano T, Seike M, Noro R, Soeno C, Chiba M, Zou F, Nakamichi S, Nishijima N, Matsumoto M, Miyanaga A, Kubota K, Gemma A. 
								Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer 
								Mol Cancer Ther 
								2015 
								14(11):2433-40 
								
									
										PubMed ID: 26351321
									
								 
								
									
										DOI: 10.1158/1535-7163.MCT-15-0050 | 
						
							
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								Kang CW, Jang KW, Sohn J, Kim SM, Pyo KH, Kim H, Yun MR, Kang HN, Kim HR, Lim SM, Moon YW, Paik S, Kim DJ, Kim JH, Cho BC. 
								Antitumor Activity and Acquired Resistance Mechanism of Dovitinib (TKI258) in RET-Rearranged Lung Adenocarcinoma 
								Mol Cancer Ther 
								2015 
								14(10):2238-48 
								
									
										PubMed ID: 26208525
									
								 
								
									
										DOI: 10.1158/1535-7163.MCT-15-0350 | 
						
							
							| 15182 
								Saito K, Kobayashi M, Nagashio R, Ryuge S, Katono K, Nakashima H, Tsuchiya B, Jiang SX, Saegusa M, Satoh Y, Masuda N, Sato Y. 
								S100A16 is a Prognostic Marker for Lung Adenocarcinomas 
								Asian Pac J Cancer Prev 
								2015 
								16(16):7039-44 
								
									
										PubMed ID: 26514487
									
								 
								
									
										DOI: 10.7314/apjcp.2015.16.16.7039 | 
						
							
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								Yanagita K, Nagashio R, Ryuge S, Katono K, Jiang SX, Tsuchiya B, Nakashima H, Fukuda E, Goshima N, Saegusa M, Satoh Y, Masuda N, Sato Y. 
								Serum Anti-Gal-3 Autoantibody is a Predictive Marker of the Efficacy of Platinum-Based Chemotherapy against Pulmonary Adenocarcinoma 
								Asian Pac J Cancer Prev 
								2015 
								16(17):7959-65 
								
									
										PubMed ID: 26625826
									
								 
								
									
										DOI: 10.7314/apjcp.2015.16.17.7959 | 
						
							
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								Kodama T, Tsukaguchi T, Satoh Y, Yoshida M, Watanabe Y, Kondoh O, Sakamoto H. 
								Alectinib shows potent antitumor activity against RET-rearranged non-small cell lung cancer. 
								Mol Cancer Ther 
								2014 
								13(12):2910-8 
								
									
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										DOI: 10.1158/1535-7163.MCT-14-0274 | 
						
							
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								Kitamura K, Seike M, Okano T, Matsuda K, Miyanaga A, Mizutani H, Noro R, Minegishi Y, Kubota K, Gemma A. 
								MiR-134/487b/655 cluster regulates TGF-β-induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung adenocarcinoma cells 
								Mol Cancer Ther 
								2014 
								13(2):444-53 
								
									
										PubMed ID: 24258346
									
								 
								
									
										DOI: 10.1158/1535-7163.MCT-13-0448 | 
						
							
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								Okudela K, Suzuki T, Umeda S, Tateishi Y, Mitsui H, Miyagi Y, Ohashi K. 
								A comprehensive search for microRNAs with expression profiles modulated by oncogenic KRAS: potential involvement of miR-31 in lung carcinogenesis 
								Oncol Rep 
								2014 
								32(4):1374-84 
								
									
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										DOI: 10.3892/or.2014.3339 | 
						
							
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								Huqun, Ishikawa R, Zhang J, Miyazawa H, Goto Y, Shimizu Y, Hagiwara K, Koyama N. 
								Enhancer of zeste homolog 2 is a novel prognostic biomarker in nonsmall cell lung cancer. 
								Cancer 
								2012 
								118:1599-606 
								
									
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								Kobayashi M, Matsumoto T, Ryuge S, Yanagita K, Nagashio R, Kawakami Y, Goshima N, Jiang SX, Saegusa M, Iyoda A, Satoh Y, Masuda N, Sato Y. 
								CAXII Is a sero-diagnostic marker for lung cancer 
								PLoS One 
								2012 
								7(3):e33952 
								
									
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								Shiba-Ishii A, Noguchi M. 
								Aberrant stratifin overexpression is regulated by tumor-associated CpG demethylation in lung adenocarcinoma 
								Am J Pathol 
								2012 
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								Kageyama T, Nagashio R, Ryuge S, Matsumoto T, Iyoda A, Satoh Y, Masuda N, Jiang SX, Saegusa M, Sato Y. 
								HADHA is a potential predictor of response to platinum-based chemotherapy for lung cancer 
								Asian Pac J Cancer Prev 
								2011 
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								Shiba-Ishii A, Kano J, Morishita Y, Sato Y, Minami Y, Noguchi M. 
								High expression of stratifin is a universal abnormality during the course of malignant progression of early-stage lung adenocarcinoma 
								Int J Cancer 
								2011 
								129(10):2445-53 
								
									
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								Hayashi S, Kumai T, Matsuda Y, Aoki N, Sato K, Kimura S, Kitada M, Tateno M, Celis E, Kobayashi H. 
								Six-transmembrane epithelial antigen of the prostate and enhancer of zeste homolog 2 as immunotherapeutic targets for lung cancer 
								J Transl Med 
								2011 
								9:191 
								
									
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										DOI: 10.1186/1479-5876-9-191 | 
						
							
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								Mizutani H, Okano T, Minegishi Y, Matsuda K, Sudoh J, Kitamura K, Noro R, Soeno C, Yoshimura A, Seike M, Gemma A. 
								HSP27 modulates epithelial to mesenchymal transition of lung cancer cells in a Smad-independent manner 
								Oncol Lett 
								2010 
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								Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y. 
								Is parainfluenza virus a threatening virus for human cancer cell lines? 
								Hum Cell 
								2009 
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