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21912
Hidehiko Kikuchi, Kaori Harata, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi
Aristolochic acid C displays cytotoxic effect and remarkable enhancing effect on the all-trans retinoic acid-induced superoxide-generating ability in U937 cells
Fundamental Toxicological Sciences
2024
11:197-204
DOI: 10.2131/fts.11.197
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19788
Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Takefumi Sagara, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi
Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-trans retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells
Fundamental Toxicological Sciences
2023
10:233-240
DOI: 10.2131/fts.10.233
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19927
Ishihara T, Tanaka KI, Takafuji A, Miura K, Mizushima T.
Attenuation of LPS-Induced Lung Injury by Benziodarone via Reactive Oxygen Species Reduction
Int J Mol Sci
2023
24(12):10035
PubMed ID: 37373184
DOI: 10.3390/ijms241210035
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17511
Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Takefumi Sagara, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi
Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells
Fundamental Toxicological Sciences
2022
9:151-157
DOI: 10.2131/fts.9.151
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20451
Phan TKT, Do TL, Tachibana K, Kihara T.
Alpha-mangostin dephosphorylates ERM to induce adhesion and decrease surface stiffness in KG-1 cells.
Hum Cell
2022
PubMed ID: 34817798
DOI: 10.1007/s13577-021-00651-8
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17332
Kikuchi H, Harata K, Akiyoshi S, Sagara T, Madhyastha H, Kuribayashi F.
Potential role of green tea amino acid l-theanine in the activation of innate immune response by enhancing expression of cytochrome b558 responsible for the reactive oxygen species-generating ability of leukocytes
Microbiol Immunol
2022
66(6):342-349
PubMed ID: 35338668
DOI: 10.1111/1348-0421.12977
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19228
Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Harishkumar Madhyastha, Futoshi Kuribayashi
3’, 4’-Dihydroxyflavone enhances all-trans retinoic acid-induced superoxide-generating activity through up-regulating transcription of gp91-phox in human monoblastic U937 cells, as opposed to flavone and other hydroxyflavone derivatives
Fundamental Toxicological Sciences
2021
8:53-59
DOI: 10.2131/fts.8.53
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14198
Zha S, Ueno M, Liang Y, Okada S, Oda T, Ishibashi F.
Induction of Apoptotic Cell Death in Human Leukemia U937 Cells by C18 Hydroxy Unsaturated Fatty Acid Isolated from Red Alga Tricleocarpa jejuensis
Mar Drugs
2021
19(3):138
PubMed ID: 33801204
DOI: 10.3390/md19030138
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14477
Zhao Y, Zhu XY, Song T, Zhang L, Eirin A, Conley S, Tang H, Saadiq I, Jordan K, Lerman A, Lerman LO.
Mesenchymal stem cells protect renal tubular cells via TSG-6 regulating macrophage function and phenotype switching
Am J Physiol Renal Physiol
2021
320(3):F454-F463
PubMed ID: 33554782
DOI: 10.1152/ajprenal.00426.2020
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20265
Kikuchi H, Harata K, Madhyastha H, Kuribayashi F.
Ellagic acid and its fermentative derivative urolithin A show reverse effects on the gp91-phox gene expression, resulting in opposite alterations in all-trans retinoic acid-induced superoxide generating activity of U937 cells.
Biochem Biophys Rep
2021
25:100891
PubMed ID: 33490645
DOI: 10.1016/j.bbrep.2020.100891
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14475
Hidehiko Kikuchi, Kaori Harata, Chikage Kawai, Harishkumar Madhyastha, Akira Yamauchi, Futoshi Kuribayashi
Retinoic acid dramatically enhances cytotoxicity of equol against human monoblastic U937 cells, but not against human peripheral neutrophils
Fundamental Toxicological Sciences
2020
7:201-206
DOI: 10.2131/fts.7.201
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6891
Sumiko Akiyoshi, Hidehiko Kikuchi, Futoshi Kuribayashi, Harishkumar Madhyastha, Hisanori Minami
Sulforaphane displays the growth inhibition, cytotoxicity and enhancement of retinoic acid-induced superoxide-generating activity in human monoblastic U937 cells
Fundamental Toxicological Sciences
2019
6:319-325
DOI: 10.2131/fts.6.319
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9138
Aki Kawano, Wataru Ariyoshi, Yoshie Yoshioka, Hisako Hikiji, Tatsuji Nishihara, Toshinori Okinaga
Docosahexaenoic Acid Enhances M2 Macrophage Polarization via the p38 Signaling Pathway and Autophagy
J Cell Biochem
2019
120 (8), 12604-12617
PubMed ID: 30825233
DOI: 10.1002/jcb.28527
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9810
Junko Shibato, Fumiko Takenoya, Takahiro Hirabayashi, Ai Kimura, Yusuke Iwasaki, Yoko Toyoda, Motohide Hori, Shigeru Tamogami, Randeep Rakwal, Seiji Shioda
Towards Identification of Bioactive Compounds in Cold Vacuum Extracted Double Cherry Blossom (Gosen-Sakura) Leaves
Plant Signal Behav
2019
14(10):e1644594
PubMed ID: 31342859
DOI: 10.1080/15592324.2019.1644594
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10626
Kikuchi H, Mimuro H, Kuribayashi F.
Resveratrol strongly enhances the retinoic acid-induced superoxide generating activity via up-regulation of gp91-phox gene expression in U937 cells.
Biochem. Biophys. Res. Commun.
2018
495:1195-1200
PubMed ID: 29183727
DOI: 10.1016/j.bbrc.2017.11.161
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4445
Hidehiko Kikuchi, Futoshi Kuribayashi, Harishkumar Madhyastha
Positions and numbers of hydroxyl groups in hydroxychalcone derivatives are involved in cytotoxicity against human monoblastic U937 cells
Fundamental Toxicological Sciences
2018
5, 149-152
DOI: 10.2131/fts.5.149
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14353
Pang L, Han S, Jiao Y, Jiang S, He X, Li P.
Bu Fei Decoction attenuates the tumor associated macrophage stimulated proliferation, migration, invasion and immunosuppression of non-small cell lung cancer, partially via IL-10 and PD-L1 regulation
Int J Oncol
2017
Jul;51(1):25-38
PubMed ID: 28534943
DOI: 10.3892/ijo.2017.4014
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14457
Okamura Y, Otani K, Sekiguchi A, Kogane T, Kakuda C, Sakamoto Y, Kodama T, Okada M, Yamawaki H.
Vasculo-protective effect of BMS-309403 is independent of its specific inhibition of fatty acid-binding protein 4
Pflugers Arch
2017
469(9):1177-1188
PubMed ID: 28405802
DOI: 10.1007/s00424-017-1976-0
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14471
Otsuka M, Okinaga T, Ariyoshi W, Kitamura C, Nishihara T.
Ameloblastin Upregulates Inflammatory Response Through Induction of IL-1β in Human Macrophages
J Cell Biochem
2017
118(10):3308-3317
PubMed ID: 28295583
DOI: 10.1002/jcb.25983
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12240
Hirofumi Sawai, Hideo Ogiso, Toshiro Okazaki
Differential changes in sphingolipids between TNF-induced necroptosis and apoptosis in U937 cells and necroptosis-resistant sublines
Leuk Res
2015
39(9):964-70
PubMed ID: 26189109
DOI: 10.1016/j.leukres.2015.06.002
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14463
Taniguchi K, Hikiji H, Okinaga T, Hashidate-Yoshida T, Shindou H, Ariyoshi W, Shimizu T, Tominaga K, Nishihara T.
Essential Role of Lysophosphatidylcholine Acyltransferase 3 in the Induction of Macrophage Polarization in PMA-Treated U937 Cells
J Cell Biochem
2015
116(12):2840-8
PubMed ID: 25994902
DOI: 10.1002/jcb.25230
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15533
Masahito Miki, Masafumi Morita
Evaluation of the Biocompatibility of a Ti-Ta-Sn Alloy Using Cell Cultures.
Materials Transactions
2015
56:1087-109
DOI: 10.2320/matertrans.M2015062
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17135
Tomoki Nishiguchi, Zedong Jiang, Mikinori Ueno, Satoshi Takeshita, Kichul Cho, Seong Woon Roh, Kyong-Hwa Kang, Kenichi Yamaguchi, Daekyung Kim, Tatsuya Oda
Reevaluation of bactericidal, cytotoxic, and macrophage-stimulating activities of commercially available Fucus vesiculosus fucoidan
ALGAE
2014
29:237-247
DOI: 10.4490/algae.2014.29.3.237
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4993
Tsubaki M, Itoh T, Satou T, Imano M, Komai M, Ogawa N, Mukai J, Nishida S.
Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
Biochem Pharmacol
2013
85(2):163-72
PubMed ID: 23085435
DOI: 10.1016/j.bcp.2012.10.009
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18999
Matsunawa M, Akagi D, Uno S, Endo-Umeda K, Yamada S, Ikeda K, Makishima M.
Vitamin D receptor activation enhances benzo[a]pyrene metabolism via CYP1A1 expression in macrophages
Drug Metab Dispos
2012
40(11):2059-66
PubMed ID: 22837390
DOI: 10.1124/dmd.112.046839
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19082
Yamawaki H, Kameshima S, Usui T, Okada M, Hara Y.
A novel adipocytokine, chemerin exerts anti-inflammatory roles in human vascular endothelial cells
Biochem Biophys Res Commun
2012
423(1):152-7
PubMed ID: 22634313
DOI: 10.1016/j.bbrc.2012.05.103
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19301
Palimkar SS, Uenishi J, Ii H.
Total synthesis and biological evaluation of (-)-apicularen A and its analogues
J Org Chem
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13725
Abe K, Ichinomiya R, Kanai T, Yamamoto K.
Effect of a Japanese energy healing method known as Johrei on viability and proliferation of cultured cancer cells in vitro
J Altern Complement Med
2012
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7684
Kim SH, Yamamoto T, Fourmy D, Fujii T.
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Small
2011
7:3239-47
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7752
Sawai H, Domae N.
Discrimination between primary necrosis and apoptosis by necrostatin-1 in Annexin V-positive/propidium iodide-negative cells.
Biochem. Biophys. Res. Commun.
2011
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7778
Phalitakul S, Okada M, Hara Y, Yamawaki H.
Vaspin prevents TNF-α-induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF-κB and PKCθ activation in cultured rat vascular smooth muscle cells.
Pharmacol. Res.
2011
64:493-500
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7822
Aida J, Higuchi S, Hasegawa Y, Nagano-Ito M, Hirabayashi Y, Banba A, Shimizu T, Kikuchi A, Saga M, Ichikawa S.
Up-regulation of ceramide glucosyltransferase during the differentiation of U937 cells.
J. Biochem.
2011
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7845
Yamawaki H, Kuramoto J, Kameshima S, Usui T, Okada M, Hara Y.
Omentin, a novel adipocytokine inhibits TNF-induced vascular inflammation in human endothelial cells.
Biochem. Biophys. Res. Commun.
2011
408:339-43
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7886
Saito Y, Nakahata S, Yamakawa N, Kaneda K, Ichihara E, Suekane A, Morishita K.
CD52 as a molecular target for immunotherapy to treat acute myeloid leukemia with high EVI1 expression.
Leukemia
2011
25:921-31
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8227
Tsubosaka Y, Murata T, Yamada K, Uemura D, Hori M, Ozaki H.
Halichlorine reduces monocyte adhesion to endothelium through the suppression of nuclear factor-kappaB activation.
J. Pharmacol. Sci.
2010
113:208-13
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18575
Nozaki H, Yanagida M, Koide K, Shiotani K, Kinoshita M, Kobayashi Y, Watarai S, Nakamura K, Suzuki A, Ariga T, Kushi Y.
Production and characterization of monoclonal antibodies specific to lactotriaosylceramide
Glycobiology
2010
20(12):1631-42
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4869
Kitagawa J, Hara T, Tsurumi H, Kanemura N, Kasahara S, Shimizu M, Moriwaki H.
Cell cycle-dependent priming action of granulocyte colony-stimulating factor (G-CSF) enhances in vitro apoptosis induction by cytarabine and etoposide in leukemia cell lines.
J Clin Exp Hematop
2010
50(2):99-105
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6125
Shimahara A, Yamakawa N, Nishikata I, Morishita K.
Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA2.
J Biol Chem
2010
285(22):16967-77
PubMed ID: 20363750
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Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Astrocyte elevated gene-1 (AEG-1) is induced by lipopolysaccharide as toll-like receptor 4 (TLR4) ligand and regulates TLR4 signalling.
Immunology
2009
128:e700-6
PubMed ID: 19740331
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8579
Amano Y, Cho Y, Matsunawa M, Komiyama K, Makishima M.
Increased nuclear expression and transactivation of vitamin D receptor by the cardiotonic steroid bufalin in human myeloid leukemia cells.
J. Steroid Biochem. Mol. Biol.
2009
114:144-51
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8602
Nakayasu S, Soegima R, Yamaguchi K, Oda T.
Biological activities of fucose-containing polysaccharide ascophyllan isolated from the brown alga Ascophyllum nodosum.
Biosci. Biotechnol. Biochem.
2009
73:961-4
PubMed ID: 19352011
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6436
Hisao Haniu, Yoshikazu Matsuda, Kenji Takeuchi
Potential of a Novel Safety Evaluation of Nanomaterials Using a Proteomic Approach
Journal of Health Science
2009
55:428-434
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18998
Nakayama K, Nitto T, Inoue T, Node K.
Expression of the cytochrome P450 epoxygenase CYP2J2 in human monocytic leukocytes
Life Sci
2008
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19289
Sawai H, Domae N.
Release of cytochrome c from mitochondria precedes Bax translocation/activation in Triton X-100-induced apoptosis
Leuk Res
2008
32(3):445-53
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6804
Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
Thalidomide inhibits epidermal growth factor-induced cell growth in mouse and human monocytic leukemia cells via Ras inactivatio
Biochem Biophys Res Commun
2008
374(4):683-7
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9068
Yasuhiro Yamasaki, Daisuke Katsuo, Seiichiro Nakayasu, Cristina Salati, JingJing Duan, Yanan Zou, Yukihiko Matsuyama, Kenichi Yamaguchi, Tatsuya Oda
Purification and Characterization of a Novel High Molecular Weight Exotoxin Produced by Red Tide Phytoplankton, Alexandrium Tamarense
J Biochem Mol Toxicol
2008
22 (6), 405-15
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18871
Roy MK, Takenaka M, Kobori M, Nakahara K, Isobe S, Tsushida T.
Apoptosis, necrosis and cell proliferation-inhibition by cyclosporine A in U937 cells (a human monocytic cell line)
Pharmacol Res
2006
53(3):293-302
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16902
Fujita K, Tsujimura A, Miyagawa Y, Kiuchi H, Matsuoka Y, Takao T, Takada S, Nonomura N, Okuyama A.
Isolation of germ cells from leukemia and lymphoma cells in a human in vitro model: potential clinical application for restoring human fertility after anticancer therapy
Cancer Res
2006
66(23):11166-71
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2808
Pang, Zhongcun, Otaka, Kodo, Maoka, Takashi, Hidaka, Kumi, Ishijima, Sumio, Oda, Masayuki, Ohnishi, Masatake
Structure of beta-glucan oligomer from laminarin and its effect on human monocytes to inhibit the proliferation of U937 cells.
Biosci Biotechnol Biochem
2005
69:553-8
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3270
Inamura J, Ikuta K, Jimbo J, Shindo M, Sato K, Torimoto Y, Kohgo Y.
Upregulation of hepcidin by interleukin-1beta in human hepatoma cell lines.
Hepatol. Res.
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33:198-205
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Shiro Okumura, Hiroyuki Saitoh, Tomoyuki Ishikawa, Naoya Wasano, Satoko Yamashita, Ken-Ichi Kusumoto, Tetsuyuki Akao, Eiichi Mizuki, Michio Ohba, Kuniyo Inouye
Identification of a Novel Cytotoxic Protein, Cry45Aa, From Bacillus Thuringiensis A1470 and Its Selective Cytotoxic Activity Against Various Mammalian Cell Lines
J Agric Food Chem
2005
53 (16), 6313-8
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12837
Fujita H, Utsumi T, Muranaka S, Ogino T, Yano H, Akiyama J, Yasuda T, Utsumi K.
Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B
Biochem Pharmacol
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Hirohisa Matsushita, Hiroaki Kuwabara, Satoko Ishikawa, Masataka Mochizuki
Apoptosis Induced in Human Cell Lines by a Butanol Extract from Chlorophytum comosum Roots
Journal of Health Science
2005
51:341-345
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2848
Feng, Xingmin, Chuhjo, Tatsuya, Sugimori, Chiharu, Kotani, Takeharu, Lu, Xuzhang, Takami, Akiyoshi, Takamatsu, Hiroyuki, Yamazaki, Hirohito, Nakao, Shinji
Diazepam-binding inhibitor-related protein 1: a candidate autoantigen in acquired aplastic anemia patients harboring a minor population of paroxysmal nocturnal hemoglobinuria-type cells.
Blood
2004
104:2425-31
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Fukushima K, Ishiyama C, Yamashita K.
Recognition by TNF-alpha of the GPI-anchor glycan induces apoptosis of U937 cells.
Arch Biochem Biophys
2004
426(2):298-305
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Kobayashi H, Takemura Y, Hayashi T, Ujiiye T, Kawase M, Niino Y, Miyachi H, Ohshima T, Hotta T.
Expression level of MDR1 message in peripheral blood leukocytes from healthy adults: a competitive nucleic acid sequence-based amplification assay for its determination
Clin Chem Lab Med
2004
42(10):1098-101
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2662
Akiyama, Hidehiko, Ino, Teruo, Tokunaga, Etsuko, Katsuda, Itsurou, Ezaki, Kohji
A synergistic increase of apoptosis utilizing Fas antigen expression induced by low doses of anticancer drug.
Rinsho Byori
2003
51:733-9
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18798
Bamba H, Ota S, Kato A, Miyatani H, Kawamoto C, Yoshida Y, Fujiwara K.
Effect of rebamipide on prostaglandin receptors-mediated increase of inflammatory cytokine production by macrophages
Aliment Pharmacol Ther
2003
Suppl 1:113-8
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Matsumoto K, Akao Y, Kobayashi E, Ohguchi K, Ito T, Tanaka T, Iinuma M, Nozawa Y.
Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines.
J Nat Prod
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66(8):1124-7
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Hikasa M, Yamamoto E, Kawasaki H, Komai K, Shiozawa K, Hashiramoto A, Miura Y, Shiozawa S.
p21waf1/cip1 is down-regulated in conjunction with up-regulation of c-Fos in the lymphocytes of rheumatoid arthritis patients.
Biochem Biophys Res Commun
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304(1):143-7
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15544
MAKOTO NOGUCHI, ICHIRO ARIFUKU, AKIMICHI YAMASHITA, KENZO SATO
Induction of hepatocyte growth factor and inhibition of proliferationby extracellular matrix component derived from fish skin of Reinhararditushippoglossoides
Fisheries Science
2003
69:401-407
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Nagai, Fusako, Hiyoshi, Yasuko, Sugimachi, Kumiko, Tamura, Hiro-Omi
Cytochrome P450 (CYP) expression in human myeloblastic and lymphoid cell lines.
Biol Pharm Bull
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25:383-5
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Hashizume K, Hatanaka Y, Fukuda I, Sano T, Yamaguchi Y, Tani Y, Danno G, Suzuki K, Ashida H.
N-acetyl-L-cysteine suppresses constitutive expression of CD11a/LFA-1alpha protein in myeloid lineage
Leuk Res
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26(10):939-44
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N Kiyokawa, T Mori, T Taguchi, M Saito, K Mimori, T Suzuki, T Sekino, N Sato, H Nakajima, Y U Katagiri, T Takeda, J Fujimoto
Activation of the Caspase Cascade During Stx1-induced Apoptosis in Burkitt's Lymphoma Cells
J Cell Biochem
2001
81 (1), 128-42
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N Hasegawa, Y Kimura, T Oda, N Komatsu, T Muramatsu
Isolated Ricin B-chain-mediated Apoptosis in U937 Cells
Biosci Biotechnol Biochem
2000
64 (7), 1422-9
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Bamba H, Ota S, Kato A, Kawamoto C, Fujiwara K.
Prostaglandins up-regulate vascular endothelial growth factor production through distinct pathways in differentiated U937 cells
Biochem Biophys Res Commun
2000
273(2):485-91
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Activation of MST/Krs and c-Jun N-terminal kinases by different signaling pathways during cytotrienin A-induced apoptosis
J Biol Chem
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Kaneko A, Suzuki S, Hara M, Mori J, Kumagai M, Yajima H, Yamashita K, Kakizawa T, Yamazaki M, Takeda T, Miyamoto T, Ichikawa K, Hashizume K.
1,25-Dihydroxyvitamin D3 suppresses the expression of the VCAM-1 receptor, VLA-4 in human leukemic HL-60 cells
Biochem Biophys Res Commun
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Yano M, Kishida E, Muneyuki Y, Masuzawa Y.
Quantitative analysis of ceramide molecular species by high performance liquid chromatography
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Involvement of both caspase-like proteases and serine proteases in apoptotic cell death induced by ricin, modeccin, diphtheria toxin, and pseudomonas toxin
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1998
124(5):1038-44
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Alteration of pharmacokinetics and nephrotoxicity of cisplatin by alginates
J Pharm Sci
1997
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The perturbed membrane of cells undergoing apoptosis is susceptible to type II secretory phospholipase A2 to liberate arachidonic acid
Biochim Biophys Acta
1997
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Structural and functional analysis of the promoter region of the human MCP-3 gene: transactivation of expression by novel recognition sequences adjacent to the transcription initiation site.
DNA Cell Biol
1997
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Isoda H, Shinmoto H, Matsumura M, Nakahara T.
Succinoyl trehalose lipid induced differentiation of human monocytoid leukemic cell line U937 into monocyte-macrophages
Cytotechnology
1995
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Koseki T, Yamato K, Krajewski S, Reed JC, Tsujimoto Y, Nishihara T.
Activin A-induced apoptosis is suppressed by BCL-2
FEBS Lett
1995
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Adenosine as an endogenous mediator of hypoxia for induction of vascular endothelial growth factor mRNA in U-937 cells.
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1994
204:318-24
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Role of cell surface O-linked oligosaccharides in adhesion of HL60 cells to fibronectin: regulation of integrin-dependent cell adhesion by O-linked oligosaccharide elongation
Exp Cell Res
1994
214(2):537-42
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Yoshikatsu Ogawa, Yoshimitsu Yamazaki, Hiroaki Okuno
Stereoselectivity in the hydrolysis of synthetic esters by cultured cancer cells and normal tissue extracts of rat
Bioorganic & Medicinal Chemistry Letters
1994
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A new DNA profiling system for cell line identification for use in cell banks in Japan.
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1992
28A:24-8
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