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細胞番号 : 細胞名
RCB0431 : T24  update : 2022/07/13
細胞特性(Comment:英)Bladder transitional-cell carcinoma
使用条件(英)Research purpose only. Send APPROVAL Form(C-0006) directly to RCB.
使用条件(日)研究目的のみに限る。理化学研究所 細胞材料開発室に承諾書を直接送ること。
理化学研究所   細胞材料開発室
提供 係 先生
Fax. 029-836-9130

Contact Us
RIKEN, BioResource Research Center
Cell Engineering Division
Dr.Cell Bank
Fax. +81-29-836-9130
提供申込書類(英) Order Form(C-0005.pdf)   Approval Form(C-0006.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   承諾書C-0002.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 RCB (Noda, Makoto)
樹立者 Bubenick, J.
寄託日 1989
動物種 human < Mammals
属名 Homo
種名 sapiens
性別 Female
81 years
採取組織 bladder
病名 transitional-cell carcinoma
細胞分類 cancer
細胞寿命 infinite
細胞形態 epithelial-like
Cellosaurus(Expasy) CVCL_0554
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 McCoy's 5A + 10% FBS
抗生物質 Free
継代方法 0.25% Trypsin
継代密度 1 : 8 split
継代・培地交換頻度 Subculture : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
ウィルス(HIV) (-)
アイソザイム検査 LD, NP
染色体検査 79-90(50) : /81(3),82(10),83(8),84(5),85(13),86(1)/
個体識別検査 OK
文献情報 Reference(英) 6件
Reference(日) 2件
利用者成果(英) 12件
利用者成果(日) 0件

190  Bubeník J, Kieler J, Tromholt V, Steven K, Indrová M, Toulcová A.  Activation of killer cells from blood of urinary bladder carcinoma patients by short-term treatment with recombinant interleukin 2  Folia Biol (Praha)  1986  32(3):183-94  PubMed ID: 3488923  
189  Bubeńik J, Kieler J, Perlmann P, Paulie S, Koho H, Christensen B, Dienstbier Z, Koprivová H, Pospísil J, Poucková P.  Monoclonal antibodies against human urinary bladder carcinomas: selectivity and utilization for gamma scintigraphy  Eur J Cancer Clin Oncol  1985  21(6):701-10  PubMed ID: 3894033   DOI: 10.1016/0277-5379(85)90267-6
191  Bubeník J, Kieler J, Perlmann P, Paulie S, Koho H, Christensen B, Dienstbier Z, Koprivová H, Pospísil J, Novák F.  Tumour localization of radiolabelled monoclonal antibody in mice bearing human urinary bladder (T24) carcinoma xenografts  Folia Biol (Praha)  1985  31(2):176-84  PubMed ID: 3894060  
4680  Capon DJ, Chen EY, Levinson AD, Seeburg PH, Goeddel DV.  Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue.  Nature  1983  302:33-7  PubMed ID: 6298635   DOI: 10.1038/302033a0
1173  Bubeník J, Baresová M, Viklický V, Jakoubková J, Sainerová H, Donner J.  Established cell line of urinary bladder carcinoma (T24) containing tumour-specific antigen.  Int J Cancer  1973  11(3):765-73  PubMed ID: 4133950   DOI: 10.1002/ijc.2910110327
1172  Bubeník J, Perlmann P, Helmstein K, Moberger G.  Cellular and humoral immune responses to human urinary bladder carcinomas.  Int J Cancer  1970  5(3):310-9  PubMed ID: 5452065   DOI: 10.1002/ijc.2910050303

1713  清水憲二  ヒト : T24  生体の科学  1992  43:408   
1260  藤田潤  バイオテクノロジ-素材としての培養細胞 癌遺伝子  蛋白質 核酸 酵素  1988  33:2537-2538   

16352  Shimizu R, Ohira T, Yagyu T, Yumioka T, Yamaguchi N, Iwamoto H, Morizane S, Hikita K, Honda M, Takenaka A, Kugoh H.  Activation of PPARγ in bladder cancer via introduction of the long arm of human chromosome 9  Oncol Lett  2022  23(3):92  PubMed ID: 35154423   DOI: 10.3892/ol.2022.13212
11877  Nozaki S, Nakatani Y, Mawatari A, Shibata N, Hume WE, Hayashinaka E, Wada Y, Doi H, Watanabe Y.  18F-FIMP: a LAT1-specific PET probe for discrimination between tumor tissue and inflammation.  Sci Rep  2019    PubMed ID: 31673030   DOI: 10.1038/s41598-019-52270-x
14444  Kameyama K, Horie K, Mizutani K, Kato T, Fujita Y, Kawakami K, Kojima T, Miyazaki T, Deguchi T, Ito M.  Enzalutamide inhibits proliferation of gemcitabine-resistant bladder cancer cells with increased androgen receptor expression  Int J Oncol  2017  50(1):75-84  PubMed ID: 27909718   DOI: 10.3892/ijo.2016.3781
5877  Yamamoto H, Okumura K, Toshima S, Mukaisho K, Sugihara H, Hattori T, Kato M, Asano S.  FXYD3 protein involved in tumor cell proliferation is overproduced in human breast cancer tissues.  Biol Pharm Bull  2009  32(7):1148-54  PubMed ID: 19571376   DOI: 10.1248/bpb.32.1148
13714  Futami K, Kumagai E, Makino H, Goto H, Takagi M, Shimamoto A, Furuichi Y.  Induction of mitotic cell death in cancer cells by small interference RNA suppressing the expression of RecQL1 helicase  Cancer Sci  2008  99(1):71-80  PubMed ID: 17953710   DOI: 10.1111/j.1349-7006.2007.00647.x
9046  Shin-ichi Kohno 1, Chenhong Luo, Fumi Goshima, Yukihiro Nishiyama, Tetsutaro Sata, Yoshinari Ono  Herpes Simplex Virus Type 1 Mutant HF10 Oncolytic Viral Therapy for Bladder Cancer  Urology  2005  66 (5), 1116-21  PubMed ID: 16286150   DOI: 10.1016/j.urology.2005.05.041
2531  Masters JR, Thomson JA, Daly-Burns B, Reid YA, Dirks WG, Packer P, Toji LH, Ohno T, Tanabe H, Arlett CF, Kelland LR, Harrison M, Virmani A, Ward TH, Ayres KL, Debenham PG.  Short tandem repeat profiling provides an international reference standard for human cell lines.  Proc Natl Acad Sci U S A.  2001  98(14):8012-7  PubMed ID: 11416159   DOI: 10.1073/pnas.121616198
16905  Kawai K, Hayashi H, Ozaki Y, Saijo K, Liu SQ, Akaza H, Ohno T.  Assessment of the number of local cytotoxic T lymphocytes required for degradation of micrometer-size tumor spheroids  Cytotechnology  2001  37(1):31-40  PubMed ID: 19002912   DOI: 10.1023/A:1016139010531
3759  Kataoka H, Uchino H, Iwamura T, Seiki M, Nabeshima K, Koono M.  Enhanced tumor growth and invasiveness in vivo by a carboxyl-terminal fragment of alpha1-proteinase inhibitor generated by matrix metalloproteinases: a possible modulatory role in natural killer cytotoxicity.  Am J Pathol  1999  154(2):457-68  PubMed ID: 10027404   DOI: 10.1016/s0002-9440(10)65292-3
5969  Morita M, Yoshiuchi N, Arakawa H, Nishimura S.  CMAP: a novel cystatin-like gene involved in liver metastasis.  Cancer Res  1999  59(1):151-8  PubMed ID: 9892200  
2181  Ryusuke Futatsuya M.D., Ph.D. Hitomi Kimura M.D. Masatoshi Maeda Ph.D. Miki Shoji Ph.D. Takashi Honda Ph.D.  Assessment of intrinsic radiosensitivity of human bladder cancer cell lines using colorimetric‐MTT and micronucleus assays  Radiation Oncology Investigations  1996  4:249-254    DOI: 10.1002/(SICI)1520-6823
1902  Shu Qin Liu, Kaoru Saijo, Makoto Kodama, Tadao Ohno  Intelligent matrices for tumor-specific cytotoxic T lymphocytes  Materials Science and Engineering: C  1994  2:61-65    DOI: 10.1016/0928-4931(94)90030-2


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