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細胞番号 : 細胞名
RCB0285 : CHO-K1  update : 2024/06/07
細胞特性(Comment:英)A cell line derived from ovary of Chinese hamster. Frequently used for production of recombinant proteins etc.
使用条件(英)There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
提供申込書類(英) Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 Seto, Toshio
樹立者 Puck, T. T.
寄託日 1989
動物種 _hamster < Mammals
動物系統名 Chinese
属名 Cricetulus
種名 griseus
性別 Female
採取組織 ovary
細胞分類 other
細胞寿命 infinite
細胞形態 epithelial-like
Cellosaurus(Expasy) CVCL_0214
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 HamF12 + 10% FBS
抗生物質 Free
継代方法 0.25% Trypsin
継代密度 1 : 8 split
継代・培地交換頻度 Subculture : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
染色体検査 17-58(50) : 17(3),18(3),19(10),20(21),21(6),26(1)/
文献情報 Reference(英) 3件
Reference(日) 6件
利用者成果(英) 161件
利用者成果(日) 0件

2587  albantoglu J, Hartley D, Phear G, Tear G, Meuth M.  Spontaneous deletion formation at the aprt locus of hamster cells: the presence of short sequence homologies and dyad symmetries at deletion termini  EMBO J  1986  5(6):1199-204  PubMed ID: 3015589   DOI: 10.1002/j.1460-2075.1986.tb04347.x
1068  Kao, F T, Puck, T T  Genetics of somatic mammalian cells, VII. Induction and isolation of nutritional mutants in Chinese hamster cells.  Proc Natl Acad Sci U S A  1968  60:1275-81  PubMed ID: 5244736   DOI: 10.1073/pnas.60.4.1275
2586  Puck, T. T. et al  Genetics of somatic mammalian cells. III. Long-term cultivation of euploid cells from human and animal subjects.  J Exp Med  1958  108:945  PubMed ID: 13598821   DOI: 10.1084/jem.108.6.945

2588  荒谷康昭  チャイニーズハムスター:CHO  生体の科学  1992  43:444   
1224  西島正弘  バイオテクノロジ-素材としての培養細胞 体細胞遺伝学  蛋白質 核酸 酵素  1988  33:287   
1234  吉村昭彦  バイオテクノロジ-素材としての培養細胞 ホルモン・生理活性物質  蛋白質 核酸 酵素  1988  33:1153-1154   
1245  西島正弘  バイオテクノロジ-素材としての培養細胞 細胞周期  蛋白質 核酸 酵素  1988  33:1327-1328   
1252  津田弘久,乾直道  バイオテクノロジ-素材としての培養細胞 突然変異・細胞毒性アッセイ  蛋白質 核酸 酵素  1988  33:1825-1827   
1278  西島正弘  バイオテクノロジ-素材としての培養細胞 生化学実験  蛋白質 核酸 酵素  1988  33:1576-1580   

19891  Rahman MR, Kawabe Y, Suzuki K, Chen S, Amamoto Y, Kamihira M.  Inducible transgene expression in CHO cells using an artificial transcriptional activator with estrogen-binding domain  Biotechnol J  2024  19(1):e2300362.   PubMed ID: 38161242   DOI: 10.1002/biot.202300362
21681  Michinaga S, Nagata A, Ogami R, Ogawa Y, Hishinuma S.  Histamine H1 Receptor-Mediated JNK Phosphorylation Is Regulated by Gq Protein-Dependent but Arrestin-Independent Pathways.  Int J Mol Sci  2024  25(6):10.3390/ijms25063395  PubMed ID: 38542369   DOI: 10.3390/ijms25063395
21737  Shiomi A, Kaneko T, Nishikawa K, Tsuchida A, Isoshima T, Sato M, Toyooka K, Doi K, Nishikii H, Shintaku H.  High-throughput mechanical phenotyping and transcriptomics of single cells.  Nat Commun  2024  15(1):3812  PubMed ID: 38760380   DOI: 10.1038/s41467-024-48088-5
19633  Okuno M, Tsuru N, Yoshino S, Gotoh Y, Yamamoto T, Hayashi T, Ogura Y.  Isolation and Genomic Characterization of a Heat-Labile Enterotoxin 1-Producing Escherichia fergusonii Strain from a Human  Microbiol Spectr  2023  11(4):e0049123  PubMed ID: 37432125   DOI: 10.1128/spectrum.00491-23
19897  Ying B, Kawabe Y, Zheng F, Amamoto Y, Kamihira M.  High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional Positive Feedback Loop of Transactivator in CHO Cells  Cells  2023  12(22):2638  PubMed ID: 37998372   DOI: 10.3390/cells12222638
19930  Ali H, Kobayashi M, Morito K, Hasi RY, Aihara M, Hayashi J, Kawakami R, Tsuchiya K, Sango K, Tanaka T.  Peroxisomes attenuate cytotoxicity of very long-chain fatty acids  Biochim Biophys Acta Mol Cell Biol Lipids  2023  1868(2):159259  PubMed ID: 36460260   DOI: 10.1016/j.bbalip.2022.159259
20990  Wang Y, Suzuki R, Fujii A, Ieki K, Goda W, Yasui M, Abe Y.  A tyrosine-based YXXΦ motif regulates the degradation of aquaporin-4 via both lysosomal and proteasomal pathways and is functionally inhibited by a ten-amino-acid sequence within its C-terminus.  FEBS J  2023    PubMed ID: 36597763   DOI: 10.1111/febs.16717
21204  Islam MM, Sasaki O, Yano-Nashimoto S, Okamatsu-Ogura Y, Yamaguchi S.  Cibacron blue 3G-A is a novel inhibitor of Otopetrin 1 (OTOP1), a proton channel.  Biochem Biophys Res Commun  2023  665:64-70  PubMed ID: 37149984   DOI: 10.1016/j.bbrc.2023.04.112
21216  Michinaga S, Nagata A, Ogami R, Ogawa Y, Hishinuma S.  Differential regulation of histamine H1 receptor-mediated ERK phosphorylation by Gq proteins and arrestins.  Biochem Pharmacol  2023  213:115595  PubMed ID: 37201878   DOI: 10.1016/j.bcp.2023.115595
21249  Mori K, Naganuma T, Kihara A.  Role of 2-hydroxy acyl-CoA lyase HACL2 in odd-chain fatty acid production via α-oxidation in vivo.  Mol Biol Cell  2023  mbcE23020042  PubMed ID: 37285239   DOI: 10.1091/mbc.E23-02-0042
17498  Imaizumi A, Obata T, Kershaw J, Tachibana Y, Abe Y, Shibata S, Nitta N, Aoki I, Yasui M, Higashi T.  Quantitative measurement of diffusion-weighted imaging signal using expression-controlled aquaporin-4 cells: Comparative study of 2-compartment and diffusion kurtosis imaging models  PLoS One  2022  17(4):e0266465.  PubMed ID: 35439261   DOI: 10.1371/journal.pone.0266465
17613  Ali H, Morito K, Hasi RY, Aihara M, Hayashi J, Kawakami R, Kanemaru K, Tsuchiya K, Sango K, Tanaka T.  Characterization of uptake and metabolism of very long-chain fatty acids in peroxisome-deficient CHO cells  Biochim Biophys Acta Mol Cell Biol Lipids  2022  1867(2):159088  PubMed ID: 34848380   DOI: 10.1016/j.bbalip.2021.159088
16354  Koike M, Yutoku Y, Koike A.  Feline XRCC4 undergoes rapid Ku-dependent recruitment to DNA damage sites  FEBS Open Bio  2022  Jan 9  PubMed ID: 35000298   DOI: 10.1002/2211-5463.13363
20646  Herrera SA, Grifell-Junyent M, Pomorski TG.  NBD-lipid Uptake Assay for Mammalian Cell Lines.  Bio Protoc  2022  12(4):e4330  PubMed ID: 35340299   DOI: 10.21769/BioProtoc.4330
20809  Yagi H, Takahata Y, Murakami T, Nakaminami Y, Hagino H, Yamamoto S, Murakami S, Hata K, Nishimura R.  Transcriptional regulation of FRZB in chondrocytes by Osterix and Msx2.  J Bone Miner Metab  2022    PubMed ID: 35763224   DOI: 10.1007/s00774-022-01345-3
20823  Shi Y, Yasui M, Hara-Chikuma M.  AQP9 transports lactate in tumor-associated macrophages to stimulate an M2-like polarization that promotes colon cancer progression.  Biochem Biophys Rep  2022  31:101317  PubMed ID: 35967760   DOI: 10.1016/j.bbrep.2022.101317
20019  Chau S, Fujii A, Wang Y, Vandebroek A, Goda W, Yasui M, Abe Y.  Di-lysine motif-like sequences formed by deleting the C-terminal domain of aquaporin-4 prevent its trafficking to the plasma membrane.  Genes Cells  2021    PubMed ID: 33474763   DOI: 10.1111/gtc.12829
20045  Akimoto H, Sugihara M, Hishinuma S.  Differential Regulation of Bilastine Affinity for Human Histamine H1 Receptors by Lys 179 and Lys 191 via Its Binding Enthalpy and Entropy.  Pediatr Res  2021  22(4)  PubMed ID: 33562121   DOI: 10.3390/ijms22041655
20117  Araki R, Yasubuchi A, Ikegaya M, Hojo C, Tachioka H, Kawai K, Omote M, Kita A, Yabe T.  Ferulic acid alleviates abnormal behaviors in isolation-reared mice via 5-HT1A receptor partial agonist activity.  Psychopharmacology (Berl)  2021    PubMed ID: 33829309   DOI: 10.1007/s00213-021-05839-2
20484  Wu D, Arakawa H, Fujita A, Hashimoto H, Hibi M, Naruse K, Kamei Y, Sato C, Kitajima K.  A point-mutation in the C-domain of CMP-sialic acid synthetase leads to lethality of medaka due to protein insolubility.  Sci Rep  2021  11(1):23211  PubMed ID: 34853329   DOI: 10.1038/s41598-021-01715-3
6934  Baba K, Kuwada S, Nakao A, Li X, Okuda N, Nishida A, Mitsuda S, Fukuoka N, Kakeya H, Kataoka T.  Different localization of lysosomal-associated membrane protein 1 (LAMP1) in mammalian cultured cell lines.  Histochem Cell Biol  2020    PubMed ID: 31907597   DOI: 10.1007/s00418-019-01842-z
12404  Terumitsu-Tsujita M, Kitaura H, Miura I, Kiyama Y, Goto F, Muraki Y, Ominato S, Hara N, Simankova A, Bizen N, Kashiwagi K, Ito T, Toyoshima Y, Kakita A, Manabe T, Wakana S, Takebayashi H, Igarashi H.  Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model  J Neurochem  2020  154(1):25-40  PubMed ID: 31587290   DOI: 10.1111/jnc.14887
13138  Kobayashi C, Tanaka A, Yasuda T, Hishinuma S.  Roles of Lys191 and Lys179 in regulating thermodynamic binding forces of ligands to determine their binding affinity for human histamine H1 receptors.  Biochem Pharmacol  2020    PubMed ID: 32738199   DOI: 10.1016/j.bcp.2020.114185
13146  Ertunc N, Sato C, Kitajima K.  Sialic acid sulfation is induced by the antibiotic treatment in mammalian cells.  Biosci Biotechnol Biochem  2020    PubMed ID: 32752946   DOI: 10.1080/09168451.2020.1792763
13181  Nakazawa K, Shichino Y, Iwasaki S, Shiina N.  Implications of RNG140 (caprin2)-mediated translational regulation in eye lens differentiation.  J Biol Chem  2020    PubMed ID: 32839273   DOI: 10.1074/jbc.RA120.012715
13340  Hara-Chikuma M, Tanaka M, Verkman AS, Yasui M.  Inhibition of aquaporin-3 in macrophages by a monoclonal antibody as potential therapy for liver injury.  Nat Commun  2020    PubMed ID: 33168815   DOI: 10.1038/s41467-020-19491-5
11515  Fukuda N, Senga Y, Honda S.  Anxa2- and Ctsd-knockout CHO cell lines to diminish the risk of contamination with host cell proteins.  Biotechnol. Prog.  2019    PubMed ID: 30972970   DOI: 10.1002/btpr.2820
11573  Wu A, Grela E, Wójtowicz K, Filipczak N, Hamon Y, Luchowski R, Grudziński W, Raducka-Jaszul O, Gagoś M, Szczepaniak A, Chimini G, Gruszecki WI, Trombik T.  ABCA1 transporter reduces amphotericin B cytotoxicity in mammalian cells.  Cell. Mol. Life Sci.  2019    PubMed ID: 31134303   DOI: 10.1007/s00018-019-03154-w
11673  Hanako Tauchi, Chikahiro Imashiro, Taiki Kuribara, Genichiro Fujii, Yuta Kurashina, Kiichiro Totani, Kenjiro Takemura  Effective and Intact Cell Detachment from a Clinically Ubiquitous Culture Flask by Combining Ultrasonic Wave Exposure and Diluted Trypsin  Biotechnology and Bioprocess Engineering  2019      DOI: 10.1007/s12257-018-0491-2
6941  Yamamoto S, Iwamaru Y, Shimizu Y, Ueda Y, Sato M, Yamaguchi K, Nakanishi J.  Epidermal growth factor-nanoparticle conjugates change the activity from anti-apoptotic to pro-apoptotic at membrane rafts.  Acta Biomater  2019  88:383-391  PubMed ID: 30794990   DOI: 10.1016/j.actbio.2019.02.026
11919  Yachi Y, Yoshii Y, Matsuya Y, Mori R, Oikawa J, Date H.  Track Structure Study for Energy Dependency of Electrons and X-rays on DNA Double-Strand Break Induction.  Sci Rep  2019    PubMed ID: 31776470   DOI: 10.1038/s41598-019-54081-6
11172  Nakade S, Mochida K, Kunii A, Nakamae K, Aida T, Tanaka K, Sakamoto N, Sakuma T, Yamamoto T.  Biased genome editing using the local accumulation of DSB repair molecules system.  Nat Commun  2018  9(1):3270  PubMed ID: 30115916   DOI: 10.1038/s41467-018-05773-6
11085  Matsuya Y, McMahon SJ, Tsutsumi K, Sasaki K, Okuyama G, Yoshii Y, Mori R, Oikawa J, Prise KM, Date H.  Investigation of dose-rate effects and cell-cycle distribution under protracted exposure to ionizing radiation for various dose-rates.  Sci Rep  2018  8(1):8287  PubMed ID: 29844494   DOI: 10.1038/s41598-018-26556-5
11155  Yasui M, Hiroshima M, Kozuka J, Sako Y, Ueda M.  Automated single-molecule imaging in living cells.  Nat Commun  2018  9(1):3061  PubMed ID: 30076305   DOI: 10.1038/s41467-018-05524-7
11346  Hishinuma S, Tamura Y, Kobayashi C, Akatsu C, Shoji M.  Differential Regulation of Thermodynamic Binding Forces of Levocetirizine and (S)-Cetirizine by Lys191 in Human Histamine H₁ Receptors.  Int J Mol Sci  2018    PubMed ID: 30558340   DOI: 10.3390/ijms19124067
4064  Tomoki Ohkubo, Haruyuki Kinoshita, View ORCID ProfileToshiro Maekawa, Katsuyuki Kunida, Hiroshi Kimura, Shinya Kuroda, Teruo Fujii  Development of a microfluidic cell culture and monitoring system for intracellular signaling studies  bioRxiv  2018      DOI: 10.1101/453100
4177  Hishinuma S, Komazaki H, Tsukamoto H, Hatahara H, Fukui H, Shoji M.  Ca2+ -dependent down-regulation of human histamine H1 receptors in Chinese hamster ovary cells.  J. Neurochem.  2018    PubMed ID: 29063596   DOI: 10.1111/jnc.14245
4474  Hiroshima M, Pack CG, Kaizu K, Takahashi K, Ueda M, Sako Y.  Transient Acceleration of Epidermal Growth Factor Receptor Dynamics Produces Higher-Order Signaling Clusters.  J. Mol. Biol.  2018  430(9):1386-1401  PubMed ID: 29505756   DOI: 10.1016/j.jmb.2018.02.018
14493  Aizawa Y, Sunada S, Hirakawa H, Fujimori A, Kato TA, Uesaka M.  Design and evaluation of a novel flavonoid-based radioprotective agent utilizing monoglucosyl rutin  J Radiat Res  2018  59(3):272-281  PubMed ID: 29373678   DOI: 10.1093/jrr/rrx090
14916  Yoshida S, Fujiwara K, Nishihara H, Kato T, Yashiro T, Kato Y.  Retinoic acid signalling is a candidate regulator of the expression of pituitary-specific transcription factor Prop1 in the developing rodent pituitary  J Neuroendocrinol  2018  30(3):e12570  PubMed ID: 29356182   DOI: 10.1111/jne.12570
7011  Saito F, Hirayasu K, Satoh T, Wang CW, Lusingu J, Arimori T, Shida K, Palacpac NMQ, Itagaki S, Iwanaga S, Takashima E, Tsuboi T, Kohyama M, Suenaga T, Colonna M, Takagi J, Lavstsen T, Horii T, Arase H.  Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors.  Nature  2017  552:101-105  PubMed ID: 29186116   DOI: 10.1038/nature24994
7033  Wakisaka N, Miyasaka N, Koide T, Masuda M, Hiraki-Kajiyama T, Yoshihara Y.  An Adenosine Receptor for Olfaction in Fish.  Curr. Biol.  2017  27:1437-1447.e4  PubMed ID: 28502661   DOI: 10.1016/j.cub.2017.04.014
9798  Takagi Y, Yamazaki T, Masuda K, Nishii S, Kawakami B, Omasa T.  Identification of regulatory motifs in the CHO genome for stable monoclonal antibody production.  Cytotechnology  2017  69:451-460  PubMed ID: 27544513   DOI: 10.1007/s10616-016-0017-8
10000  Matsuya Y, Tsutsumi K, Sasaki K, Yoshii Y, Kimura T, Date H.  Modeling cell survival and change in amount of DNA during protracted irradiation.  J. Radiat. Res.  2017  58:302-312  PubMed ID: 27974510   DOI: 10.1093/jrr/rrw110
10238  Kinashi Y, Yokomizo N, Takahashi S.  DNA Double-strand Breaks Induced byFractionated Neutron Beam Irradiation for Boron Neutron Capture Therapy.  Anticancer Res.  2017  37:1681-1685  PubMed ID: 28373429   DOI: 10.21873/anticanres.11499
4528  Quazi T.H.Shubhra, Ayako Oyane, Maki Nakamura, Sandra Puentes, Aiki Marushima, HideoTsurushima  Rapid one-pot fabrication of magnetic calcium phosphate nanoparticles immobilizing DNA and iron oxide nanocrystals using injection solutions for magnetofection and magnetic targeting  Materials Today Chemistry  2017  6, 51-61    DOI: 10.1016/j.mtchem.2017.10.001
14029  Shibuya Y, Haga N, Asano R, Nakazawa H, Hattori T, Takeda D, Sugiyama A, Kurotani R, Kumagai I, Umetsu M, Makabe K.  Generation of camelid VHH bispecific constructs via in-cell intein-mediated protein trans-splicing  Protein Eng Des Sel  2017  30(1):15-21  PubMed ID: 27881685   DOI: 10.1093/protein/gzw057
14440  Shim I, Choi K, Hirano S.  Oxidative stress and cytotoxic effects of silver ion in mouse lung macrophages J774.1 cells  J Appl Toxicol  2017  37(4):471-478  PubMed ID: 27624343   DOI: 10.1002/jat.3382
13553  Ohta A, Tsunoda Y, Tamura Y, Iino K, Nishimura N, Nishihara H, Takanashi H, Yoshida S, Kato T, Kato Y.  Construction and expression of vectors encoding biologically active rodent gonadotropins  J Reprod Dev  2017  63(6):605-609  PubMed ID: 29033405   DOI: 10.1262/jrd.2017-091
14670  Hishinuma S, Kosaka K, Akatsu C, Uesawa Y, Fukui H, Shoji M.  Asp73-dependent and -independent regulation of the affinity of ligands for human histamine H 1 receptors by Na  Biochem Pharmacol  2017  128:46-54  PubMed ID: 28040476   DOI: 10.1016/j.bcp.2016.12.021
14672  Shubhra QTH, Oyane A, Araki H, Nakamura M, Tsurushima H.  Calcium phosphate nanoparticles prepared from infusion fluids for stem cell transfection: process optimization and cytotoxicity analysis  Biomater Sci  2017  5(5):972-981  PubMed ID: 28211929   DOI: 10.1039/c6bm00870d
14742  Nakayama K, Ohashi R, Shinoda Y, Yamazaki M, Abe M, Fujikawa A, Shigenobu S, Futatsugi A, Noda M, Mikoshiba K, Furuichi T, Sakimura K, Shiina N.  RNG105/caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation  Elife  2017  6:e29677  PubMed ID: 29157358   DOI: 10.7554/eLife.29677
9555  Watanabe S, Moniaga CS, Nielsen S, Hara-Chikuma M.  Aquaporin-9 facilitates membrane transport of hydrogen peroxide in mammalian cells.  Biochem. Biophys. Res. Commun.  2016  471:191-7  PubMed ID: 26837049   DOI: 10.1016/j.bbrc.2016.01.153
12635  Teye K, Numata S, Ishii N, Krol RP, Tsuchisaka A, Hamada T, Koga H, Karashima T, Ohata C, Tsuruta D, Saya H, Haftek M, Hashimoto T.  Isolation of All CD44 Transcripts in Human Epidermis and Regulation of Their Expression by Various Agents  PLoS One  2016  11(8):e0160952  PubMed ID: 27505250   DOI: 10.1371/journal.pone.0160952
12888  Marques AR, Mirzaian M, Akiyama H, Wisse P, Ferraz MJ, Gaspar P, Ghauharali-van der Vlugt K, Meijer R, Giraldo P, Alfonso P, Irún P, Dahl M, Karlsson S, Pavlova EV, Cox TM, Scheij S, Verhoek M, Ottenhoff R, van Roomen CP, Pannu NS, van Eijk M, Dekker N, Boot RG, Overkleeft HS, Blommaart E, Hirabayashi Y, Aerts JM.  Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases  J Lipid Res  2016  57(3):451-63  PubMed ID: 26724485   DOI: 10.1194/jlr.M064923
12889  Kawabe Y, Shimomura T, Huang S, Imanishi S, Ito A, Kamihira M.  Targeted transgene insertion into the CHO cell genome using Cre recombinase-incorporating integrase-defective retroviral vectors  Biotechnol Bioeng  2016  113(7):1600-10  PubMed ID: 26724679   DOI: 10.1002/bit.25923
12938  Shimura M, Shindou H, Szyrwiel L, Tokuoka SM, Hamano F, Matsuyama S, Okamoto M, Matsunaga A, Kita Y, Ishizaka Y, Yamauchi K, Kohmura Y, Lobinski R, Shimizu I, Shimizu T.  Imaging of intracellular fatty acids by scanning X-ray fluorescence microscopy  FASEB J   2016  30(12):4149-4158  PubMed ID: 27601443   DOI: 10.1096/fj.201600569R
6060  Oyane A, Araki H, Nakamura M, Shimizu Y, Shubhra QTH, Ito A, Tsurushima H.  Controlled superficial assembly of DNA-amorphous calcium phosphate nanocomposite spheres for surface-mediated gene delivery  Colloids Surf B Biointerfaces  2016  141:519-527  PubMed ID: 26896659   DOI: 10.1016/j.colsurfb.2016.02.010
13987  Kawaguchi K, Okamoto T, Morita M, Imanaka T.  Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1  Sci Rep  2016  6:30183  PubMed ID: 27456980   DOI: 10.1038/srep30183
13995  Hishinuma S, Nozawa H, Akatsu C, Shoji M.  C-terminal of human histamine H 1 receptors regulates their agonist-induced clathrin-mediated internalization and G-protein signaling  J Neurochem  2016  139(4):552-565  PubMed ID: 27566099   DOI: 10.1111/jnc.13834
14139  Kitakaze K, Mizutani Y, Sugiyama E, Tasaki C, Tsuji D, Maita N, Hirokawa T, Asanuma D, Kamiya M, Sato K, Setou M, Urano Y, Togawa T, Otaka A, Sakuraba H, Itoh K.  Protease-resistant modified human β-hexosaminidase B ameliorates symptoms in GM2 gangliosidosis model  J Clin Invest   2016  126(5):1691-703  PubMed ID: 27018595   DOI: 10.1172/JCI85300
14936  Ikeda M, Kato K, Yamaguchi M, Hamada H, Nakamura K, Sugimoto Y.  Cell Surface Antibody Retention Influences In Vivo Antitumor Activity Mediated by Antibody-dependent Cellular Cytotoxicity  Anticancer Res  2016  36(11):5937-5944  PubMed ID: 27793919   DOI: 10.21873/anticanres.11181
12289  Mitsuhiro Matsuda, Makito Koga, Knut Woltjen, Eisuke Nishida, Miki Ebisuya  Synthetic lateral inhibition governs cell-type bifurcation with robust ratios  Nat Commun  2015  6:6195  PubMed ID: 25652697   DOI: 10.1038/ncomms7195
14965  Sakuma T, Takenaga M, Kawabe Y, Nakamura T, Kamihira M, Yamamoto T.  Homologous Recombination-Independent Large Gene Cassette Knock-in in CHO Cells Using TALEN and MMEJ-Directed Donor Plasmids  Int J Mol Sci  2015  16(10):23849-66  PubMed ID: 26473830   DOI: 10.3390/ijms161023849
15125  Matsuya Y, Tsutsumi K, Sasaki K, Date H.  Evaluation of the cell survival curve under radiation exposure based on the kinetics of lesions in relation to dose-delivery time  J Radiat Res  2015  56(1):90-9  PubMed ID: 25355708   DOI: 10.1093/jrr/rru090
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