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Cell No. : Cell Name
RCB0284 : Sq-1979  update : 2022/03/09
CommentMetastatic epithelial cell
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Ando, Koichi
Originator Majima, Hideyuki
Year of deposit 1989
Original cell NR-S1
Animal _mouse < Mammals
Strain name C3H/He
Tissue cheek
Disease name carcinoma planoepitherial
Classification cancer
History Mycoplasma was decontaminated
Memo_1 Mycoplasma was eliminated with MC-210.
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_6541
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Culture medium MEM + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
SSLP(mouse) OK
Isozyme LD, NP
Images
deposit info
lot info
Reference information Reference 1
User's Publication 12


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Reference
1086  Majima H  [Repair of sublethal damage in cultured cells derived from mouse squamous cell carcinoma following an irradiation of mixed neutrons and x-rays]  Nippon Igaku Hoshasen Gakkai Zasshi  1983  43:1307-17  PubMed ID: 6424091  

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User's Publication
21629  Machida T, Sakuma K, Fuwa N, Tanaka A.  Local Low-dose Anti-PD-L1 Antibodies Improve Antitumor Effects in Oral Squamous Cell Carcinoma.  Anticancer Res  2024  44(3):993-1002  PubMed ID: 38423636   DOI: 10.21873/anticanres.16894
17186  Sakuma K, Kii T, Takahashi H, Suzuki S, Yoshikawa K, Ogawa T, Tanaka A.  An In Vivo Study of Local Administration of Low-dose Anti-PD-1 Antibody Using an Oral Cancer Cell Line  Anticancer Res  2022  42(9):4293-4303  PubMed ID: 36039414   DOI: 10.21873/anticanres.15929
20961  Horii T, Orikawa Y, Ohira Y, Eta R, Kobayashi N, Sato T, Watanabe T, Tanaka T.  Potential of Z-100, extracted from Mycobacterium tuberculosis strain Aoyama B, as a hot tumor inducer.  Cancer Cell Int  2022  22(1):392  PubMed ID: 36494701   DOI: 10.1186/s12935-022-02821-6
20202  Matsunami A, Mizuno-Kamiya M, Kawaki H, Takayama E, Ueno K, Ando M, Morimoto-Ito H, Muramatsu Y, Sumitomo S, Kondoh N.  Augmented secretion of IL-1α from mouse oral squamous cell carcinoma (OSCC) cells caused by serum deprivation and hypoxia promotes immune suppressive activity of mesenchymal stromal cells.  J Oral Biosci  2021    PubMed ID: 34153475   DOI: 10.1016/j.job.2021.06.001
11681  Hiroe Morimoto-Ito, Masako Mizuno-Kamiya, Naoki Umemura, Yoshinori Inagaki, Eiji Takayama, Harumi Kawaki, Yasunori Muramatsu, Shinichiro Sumitomo, Nobuo Kondoh  Immunosuppressive Effect of Mesenchymal Stromal Cells is Enhanced by IL-1α from Oral Squamous Cell Carcinoma Cells  The Open Dentistry Journal  2019  13:221-227    DOI: 10.2174/1874210601913010221
10705  Adachi M, Mizuno-Kamiya M, Takayama E, Kawaki H, Inagaki T, Sumi S, Motohashi M, Muramatsu Y, Sumitomo SI, Shikimori M, Yamazaki Y, Kondoh N.  Gene expression analyses associated with malignant phenotypes of metastatic sub-clones derived from a mouse oral squamous cell carcinoma Sq-1979 cell line.  Oncol Lett  2018  15:3350-3356  PubMed ID: 29435078   DOI: 10.3892/ol.2017.7648
11047    Suppressive effect of mesenchymal stromal cells on interferon-γ-producing capability of spleen cells was specifically enhanced through humoral mediator(s) from mouse oral squamous cell carcinoma Sq-1979 Cells In Vitro  Cancer Translational Medicine  2018  4, 9-16    DOI: 10.4103/ctm.ctm_34_17
11026    The producing capabilities of Interferon-γ and Interleukin-10 of spleen cells in primary and metastasized oral squamous cell carcinoma cells-implanted mice  Cancer Transl Med  2017  3:194–9    DOI: 10.4103/ctm.ctm_30_17
14354  Sumi S, Umemura N, Takayama E, Ohkoshi E, Adachi M, Mizuno-Kamiya M, Inagaki T, Kawaki H, Sumitomo S, Kondoh N.  Metastasized murine oral squamous cell carcinoma cells induce intratumoral polymorphonuclear myeloid derived suppressor cells  Oncol Rep  2017  37(5):2897-2904  PubMed ID: 28405677   DOI: 10.3892/or.2017.5575
18749  Li X, Bukawa H, Hirota M, Tsuyuki Y, Omura S, Fujita K.  Novel OK-432-conjugated tumor vaccines induce tumor-specific immunity against murine tongue cancer  J Dent Res  2003  82(8):636-4  PubMed ID: 12885850   DOI: 10.1177/154405910308200813
17923  Matsumoto K, Saga Y, Ikemura T, Sakakura T, Chiquet-Ehrismann R.  The distribution of tenascin-X is distinct and often reciprocal to that of tenascin-C  J Cell Biol  1994  125(2):483-93  PubMed ID: 7512972   DOI: 10.1083/jcb.125.2.483
17890  Saga Y, Tsukamoto T, Jing N, Kusakabe M, Sakakura T.  Murine tenascin: cDNA cloning, structure and temporal expression of isoforms  Gene  1991  104(2):177-85  PubMed ID: 1717349   DOI: 10.1016/0378-1119(91)90248-a



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