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Cell No. : Cell Name
RCB0247 : 10T1/2  update : 2024/10/04
CommentFibroblast-like cells derived from mouse embryo. Can be used for experiments regarding cell transformation.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Terasima, Toyozo
Originator Reznikoff, Catherine A.
Year of deposit 1988
Another name 10T1/2(clone8)
Animal _mouse < Mammals
Strain name C3H
Age at sampling embryo
Tissue embryo
Classification normal
Lifespan infinite
Morphology fibroblast-like
Cellosaurus(Expasy) CVCL_0190
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Culture medium BME (2mM L-Glutamine) + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage cell No 5 x 10 4 cells/60 mm dish
SC frequency Subculture : once/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
SSLP(mouse) OK
Isozyme LD, NP
Chromosome mode 65-81(50) : /75(1),76(1),77(3),78(5),79(12),80(25)/
Images
deposit info
lot info
Reference information Reference 6
User's Publication 191


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Reference
2001  Weintraub H, Davis R, Tapscott S, Thayer M, Krause M, Benezra R, Blackwell, T K, Turner D, Rupp R, Hollenberg S, et al.  The myoD gene family: nodal point during specification of the muscle cell lineage.  Science  1991  251:761-6  PubMed ID: 1846704   DOI: 10.1126/science.1846704
962  Terasima T, Yasukawa M, Kimura M  Radiation-induced transformation of 10T 1/2 mouse cells in the plateau phase: post-irradiation changes and serum dependence.  Gann  1981  72:762-8  PubMed ID: 7327374  
2000  Taylor, S M, Jones, P A  Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine.  Cell  1979  17:771-9  PubMed ID: 90553   DOI: 10.1016/0092-8674(79)90317-9
44  Paranjpe M, del Ande Eaton S, Boone, C W  Neoplasms produced from C3H/10T 1/2 cells attached to plastic plates; saturation density, anchorage dependence and serum requirement of in vitro lines correlated with growth aggressiveness in vivo.  J Cell Physiol  1978  96:63-71  PubMed ID: 659520   DOI: 10.1002/jcp.1040960108
961  Reznikoff, C A, Brankow, D W, Heidelberger C  Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.  Cancer Res  1973  33:3231-8  PubMed ID: 4357355  
176  Reznikoff CA, Bertram JS, Brankow DW, Heidelberger C.  Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division  Cancer Res  1973  33(12):3239-49  PubMed ID: 4796800  

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User's Publication
21783  Takayanagi SI, Chuganji S, Tanaka M, Wang B, Hasegawa S, Fukumoto K, Wasano N, Kakitani M, Ochiai N, Kawai Y, Ueda T, Ishikawa A, Kurimoto Y, Fukui A, Kamibayashi S, Imai E, Kunisato A, Nozawa H, Kaneko S.  A culture method with berbamine, a plant alkaloid, enhances CAR-T cell efficacy through modulating cellular metabolism.  Commun Biol  2024  7(1):685  PubMed ID: 38834758   DOI: 10.1038/s42003-024-06297-0
21798  Ichiyama-Kobayashi S, Hata K, Wakamori K, Takahata Y, Murakami T, Yamanaka H, Takano H, Yao R, Uzawa N, Nishimura R.  Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development.  JCI Insight  2024  9(11)  PubMed ID: 38855864   DOI: 10.1172/jci.insight.175486
21965  Hidaka M, Kojima M, Sakai S.  Micromixer driven by bubble-induced acoustic microstreaming for multi-ink 3D bioprinting.  Lab Chip  2024    PubMed ID: 39221588   DOI: 10.1039/d4lc00552j
22005  Nomura K, Kimira Y, Kobayashi R, Shiobara Y, Osawa Y, Kataoka-Matsushita A, Shimizu J, Wada M, Mano H.  Collagen-derived dipeptide prolyl-hydroxyproline cooperates with Foxg1 to activate the PGC-1α promoter and induce brown adipocyte-like phenotype in rosiglitazone-treated C3H10T1/2 cells  Front Nutr  2024  11:1375532  PubMed ID: 38812940   DOI: 10.3389/fnut.2024.1375532
22021  Goto R, Sakai S, Delattre C, Petit E, El Boutachfaiti R, Nakahata M.  Enzymatically cross-linkable sulfated bacterial polyglucuronic acid as an affinity-based carrier of FGF-2 for therapeutic angiogenesis.  J Biosci Bioeng  2024    PubMed ID: 39343697   DOI: 10.1016/j.jbiosc.2024.08.011
17732  Higa Y, Hiasa M, Tenshin H, Nakaue E, Tanaka M, Kim S, Nakagawa M, Shimizu S, Tanimoto K, Teramachi J, Harada T, Oda A, Oura M, Sogabe K, Hara T, Sumitani R, Maruhashi T, Yamagami H, Endo I, Matsumoto T, Tanaka E, Abe M.  The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2  Antioxidants (Basel)  2023  12(1):133  PubMed ID: 36670994   DOI: 10.3390/antiox12010133
19663  Kotani T, Mubarok W, Hananouchi T, Sakai S.  Horseradish Peroxidase-Mediated Bioprinting via Bioink Gelation by Alternately Extruded Support Material  ACS Biomater Sci Eng  2023  9(10):5804-5812  PubMed ID: 37738620   DOI: 10.1021/acsbiomaterials.3c00996
19690  Liu C, Imai M, Edahiro Y, Mano S, Takei H, Nudejima M, Kurose A, Morishita S, Ando M, Tsuneda S, Araki M, Komatsu N.  Establishment of isogenic induced pluripotent stem cells with or without pathogenic mutation for understanding the pathogenesis of myeloproliferative neoplasms  Exp Hematol  2023  118:12-20  PubMed ID: 36511286   DOI: 10.1016/j.exphem.2022.11.005
19966  Yu Y, Uchida-Fukuhara Y, Weng Y, He Y, Ikegame M, Wang Z, Yoshida K, Okamura H, Qiu L.  Neuropilin 1 (NRP1) Positively Regulates Adipogenic Differentiation in C3H10T1/2 Cells  Int J Mol Sci  2023  24(8):7394  PubMed ID: 37108554   DOI: 10.3390/ijms24087394
17601  Furuya Y, Mera H, Itokazu M, Terai S, Nakamura H, Wakitani S, Yasuda H.  Induction of chondrogenesis with a RANKL-binding peptide, WP9QY, in vitro and in vivo in a rabbit model  Biochem Biophys Res Commun  2022  602:98-104  PubMed ID: 35259590   DOI: 10.1016/j.bbrc.2022.03.019
20079  Miyoshi H, Abo K, Hosoya D, Matsuo K, Utsumi Y.  Effects of mouse fetal liver cell culture density on hematopoietic cell expansion in three-dimensional cocultures with stromal cells.  Int J Artif Organs  2022  391398821996377  PubMed ID: 33611956   DOI: 10.1177/0391398821996377
16273  Sakai S, Kotani T, Harada R, Goto R, Morita T, Bouissil S, Dubessay P, Pierre G, Michaud P, El Boutachfaiti R, Nakahata M, Kojima M, Petit E, Delattre C.  Development of phenol-grafted polyglucuronic acid and its application to extrusion-based bioprinting inks  Carbohydr Polym  2022  277:118820  PubMed ID: 34893237   DOI: 10.1016/j.carbpol.2021.118820
20692  Hayashi Y, Kawabata KC, Tanaka Y, Uehara Y, Mabuchi Y, Murakami K, Nishiyama A, Kiryu S, Yoshioka Y, Ota Y, Sugiyama T, Mikami K, Tamura M, Fukushima T, Asada S, Takeda R, Kunisaki Y, Fukuyama T, Yokoyama K, Uchida T, Hagihara M, Ohno N, Usuki K, Tojo A, Katayama Y, Goyama S, Arai F, Tamura T, Nagasawa T, Ochiya T, Inoue D, Kitamura T.  MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis.  Cell Rep  2022  39(6):110805  PubMed ID: 35545056   DOI: 10.1016/j.celrep.2022.110805
16754  Ishihara K, Kaneyasu M, Fukazawa K, Zhang R, Teramura Y.  Induction of mesenchymal stem cell differentiation by co-culturing with mature cells in double-layered 2-methacryloyloxyethyl phosphorylcholine polymer hydrogel matrices  J Mater Chem B  2022  10(14):2561-2569  PubMed ID: 34878485   DOI: 10.1039/d1tb01817e
16755  Shimohata N, Harada Y, Hayano T.  Proteomic analysis of nascent polypeptide chains that potentially induce translational pausing during elongation  Biosci Biotechnol Biochem  2022  zbac097  PubMed ID: 35749475   DOI: 10.1093/bbb/zbac097
21046  Goto R, Nakahata M, Sakai S.  Phenol-Grafted Alginate Sulfate Hydrogel as an Injectable FGF-2 Carrier.  Gels  2022  8(12)  PubMed ID: 36547342   DOI: 10.3390/gels8120818
14003  Yuzuriha A, Nakamura S, Sugimoto N, Kihara S, Nakagawa M, Yamamoto T, Sekiguchi K, Eto K.  Extracellular laminin regulates hematopoietic potential of pluripotent stem cells through integrin β1-ILK-β-catenin-JUN axis  Stem Cell Res  2021  53:102287.   PubMed ID: 33813173   DOI: 10.1016/j.scr.2021.102287
20202  Matsunami A, Mizuno-Kamiya M, Kawaki H, Takayama E, Ueno K, Ando M, Morimoto-Ito H, Muramatsu Y, Sumitomo S, Kondoh N.  Augmented secretion of IL-1α from mouse oral squamous cell carcinoma (OSCC) cells caused by serum deprivation and hypoxia promotes immune suppressive activity of mesenchymal stromal cells.  J Oral Biosci  2021    PubMed ID: 34153475   DOI: 10.1016/j.job.2021.06.001
16752  Ishii M, Ando J, Yamazaki S, Toyota T, Ohara K, Furukawa Y, Suehara Y, Nakanishi M, Nakashima K, Ohshima K, Nakauchi H, Ando M.  iPSC-Derived Neoantigen-Specific CTL Therapy for Ewing Sarcoma  Cancer Immunol Res  2021  9(10):1175-1186  PubMed ID: 34385178   DOI: 10.1158/2326-6066.CIR-21-0193
12022  Sampilvanjil A, Karasawa T, Yamada N, Komada T, Higashi T, Baatarjav C, Watanabe S, Kamata R, Ohno N, Takahashi M.  Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells.  Am. J. Physiol. Heart Circ. Physiol.  2020    PubMed ID: 31975626   DOI: 10.1152/ajpheart.00559.2019
12066  van Gastel N, Stegen S, Eelen G, Schoors S, Carlier A, Daniëls VW, Baryawno N, Przybylski D, Depypere M, Stiers PJ, Lambrechts D, Van Looveren R, Torrekens S, Sharda A, Agostinis P, Lambrechts D, Maes F, Swinnen JV, Geris L, Van Oosterwyck H, Thienpont B, Carmeliet P, Scadden DT, Carmeliet G.  Lipid availability determines fate of skeletal progenitor cells via SOX9.  Nature  2020    PubMed ID: 32103177   DOI: 10.1038/s41586-020-2050-1
13232  Sakai S, Yoshii A, Sakurai S, Horii K, Nagasuna O.  Silk fibroin nanofibers: a promising ink additive for extrusion three-dimensional bioprinting.  Mater Today Bio  2020    PubMed ID: 33083780   DOI: 10.1016/j.mtbio.2020.100078
13376  Rico P, Rodrigo-Navarro A, Sánchez Pérez L, Salmeron-Sanchez M.  Borax induces osteogenesis by stimulating NaBC1 transporter via activation of BMP pathway.  Commun Biol  2020    PubMed ID: 33247189   DOI: 10.1038/s42003-020-01449-4
13428  J.A.Lenis, P.Rico, J.L. GómezRibelles, M.A.Pacha-Olivenza, M.L.González-Martín, F.J.Bolívar  Structure, morphology, adhesion and in vitro biological evaluation of antibacterial multi-layer HA-Ag/SiO2/TiN/Ti coatings obtained by RF magnetron sputtering for biomedical applications  Materials Science and Engineering:  2020    PubMed ID: 32806245   DOI: 10.1016/j.msec.2020.111268
13857  Gantumur E, Nakahata M, Kojima M, Sakai S.  Extrusion-Based Bioprinting through Glucose-Mediated Enzymatic Hydrogelation  Int J Bioprint  2020  6(1):250  PubMed ID: 32596552   DOI: 10.18063/ijb.v6i1.250
14438  Kazuki Y, Uno N, Abe S, Kajitani N, Kazuki K, Yakura Y, Sawada C, Takata S, Sugawara M, Nagashima Y, Okada A, Hiratsuka M, Osaki M, Ferrari G, Tedesco FS, Nishikawa S, Fukumoto K, Takayanagi SI, Kunisato A, Kaneko S, Oshimura M, Tomizuka K.  Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling  Mol Ther Nucleic Acids  2020  23:629-639  PubMed ID: 33552683   DOI: 10.1016/j.omtn.2020.12.012
11367  Ishijima Y, Ohmori S, Uneme A, Aoki Y, Kobori M, Ohida T, Arai M, Hosaka M, Ohneda K.  The Gata2 repression during 3T3-L1 preadipocyte differentiation is dependent on a rapid decrease in histone acetylation in response to glucocorticoid receptor activation.  Mol. Cell. Endocrinol.  2019    PubMed ID: 30615908   DOI: 10.1016/j.mce.2019.01.002
11397  Gantumur E, Sakai S, Nakahata M, Taya M.  Horseradish peroxidase-catalyzed hydrogelation consuming enzyme-produced hydrogen peroxide in the presence of reducing sugars.  Soft Matter  2019    PubMed ID: 30672948   DOI: 10.1039/c8sm01839a
11582  Numaga-Tomita T, Shimauchi T, Oda S, Tanaka T, Nishiyama K, Nishimura A, Birnbaumer L, Mori Y, Nishida M.  TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential-dependent coupling with PTEN.  FASEB J.  2019    PubMed ID: 31162976   DOI: 10.1096/fj.201802811R
11589  Aoki H, Yamashita M, Hashita T, Nakayama M, Yagi M, Iwao T, Matsunaga T.  Isolation of induced pluripotent stem cell-derived endothelial progenitor cells from sac-like structures.  Biochem. Biophys. Res. Commun.  2019  515(4):672-678  PubMed ID: 31178142   DOI: 10.1016/j.bbrc.2019.05.179
11681  Hiroe Morimoto-Ito, Masako Mizuno-Kamiya, Naoki Umemura, Yoshinori Inagaki, Eiji Takayama, Harumi Kawaki, Yasunori Muramatsu, Shinichiro Sumitomo, Nobuo Kondoh  Immunosuppressive Effect of Mesenchymal Stromal Cells is Enhanced by IL-1α from Oral Squamous Cell Carcinoma Cells  The Open Dentistry Journal  2019  13:221-227    DOI: 10.2174/1874210601913010221
11738  Iriguchi S, Kaneko S.  In Vitro Differentiation of T Cells: From Nonhuman Primate-Induced Pluripotent Stem Cells.  Methods Mol. Biol.  2019    PubMed ID: 31396934   DOI: 10.1007/978-1-4939-9728-2_11
11743  Kawai Y, Kaneko S.  Redifferentiation of Adaptive Naïve-Like CTL from T-Cell-Derived iPSC.  Methods Mol. Biol.  2019    PubMed ID: 31396930   DOI: 10.1007/978-1-4939-9728-2_7
11765  Abe T, Sato T, Yoda T, Hoshi K.  The period circadian clock 2 gene responds to glucocorticoids and regulates osteogenic capacity.  Regen Ther  2019    PubMed ID: 31489343   DOI: 10.1016/j.reth.2019.07.006
11838  Niimi K, Adachi Y, Ishikawa H, Yamaguchi W, Kubota Y, Inagaki S, Furuyama T.  Endothelial specific deletion of FOXO1 alters pericyte coverage in the developing retina.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 31601422   DOI: 10.1016/j.bbrc.2019.10.040
6647  Takahata Y, Nakamura E, Hata K, Wakabayashi M, Murakami T, Wakamori K, Yoshikawa H, Matsuda A, Fukui N, Nishimura R.  Sox4 is involved in osteoarthritic cartilage deterioration through induction of ADAMTS4 and ADAMTS5.  FASEB J  2019  33(1):619-630  PubMed ID: 30016600   DOI: 10.1096/fj.201800259R
6878  Yano F, Ohba S, Murahashi Y, Tanaka S, Saito T, Chung UI.  Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation.  Sci Rep  2019  9(1):7666  PubMed ID: 31113964   DOI: 10.1038/s41598-019-43948-3
6884  Iriguchi S, Kaneko S.  In Vitro Differentiation of T Cells: From Human Embryonic Stem Cells and Induced Pluripotent Stem Cells.  Methods Mol Biol  2019  2048:59-70  PubMed ID: 31396929   DOI: 10.1007/978-1-4939-9728-2_6
6907  Tagaya H, Ishikawa K, Hosokawa Y, Kobayashi S, Ueoka Y, Shimada M, Ohashi Y, Mikami H, Yamamoto M, Ihara T, Kumazawa K, Sugihara K, Goshima N, Watanabe S, Semba K.  A method of producing genetically manipulated mouse mammary gland.  Breast Cancer Res  2019  21(1):1  PubMed ID: 30611295   DOI: 10.1186/s13058-018-1086-8
9893  Zhongren Hu, Shurong Hong, Yu Zhang, Huijing Dai, Shuzhen Lin, Tingyu Yi, Hongmei Zhuang  Down-regulated WDR35 Contributes to Fetal Anomaly via Regulation of Osteogenic Differentiation  Gene  2019  20;697:48-56  PubMed ID: 30790652   DOI: 10.1016/j.gene.2019.02.034
12515  Baba TT, Miyazaki T, Ohara-Nemoto Y, Nemoto TK.  Suppressive effects of N-bisphosphonate in osteoblastic cells mitigated by non-N-bisphosphonate but not by sodium-dependent phosphate cotransporter inhibitor  Cell Biochem Funct  2019  37(6):400-407  PubMed ID: 31328801   DOI: 10.1002/cbf.3418
14881  J.A. Lenis, G. Bejarano, P. Rico, J.L. Gómez Ribelles, F.J. Bolívar  Development of multilayer Hydroxyapatite - Ag/TiN-Ti coatings deposited by radio frequency magnetron sputtering with potential application in the biomedical field  Surface and Coatings Technology  2019  377:124856    DOI: 10.1016/j.surfcoat.2019.06.097
10459  Kusuyama J, Kamisono A, ChangHwan S, Amir MS, Bandow K, Eiraku N, Ohnishi T, Matsuguchi T.  Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities.  J. Cell. Physiol.  2018  233:2549-2559  PubMed ID: 28786489   DOI: 10.1002/jcp.26130
11014    Versatility of hydrogelation by dual-enzymatic reactions with oxidases and peroxidase  Biochemical Engineering Journal  2018  131, 1-8    DOI: 10.1016/j.bej.2017.12.003
11047    Suppressive effect of mesenchymal stromal cells on interferon-γ-producing capability of spleen cells was specifically enhanced through humoral mediator(s) from mouse oral squamous cell carcinoma Sq-1979 Cells In Vitro  Cancer Translational Medicine  2018  4, 9-16    DOI: 10.4103/ctm.ctm_34_17
11132  Ito Y, Nakamura S, Sugimoto N, Shigemori T, Kato Y, Ohno M, Sakuma S, Ito K, Kumon H, Hirose H, Okamoto H, Nogawa M, Iwasaki M, Kihara S, Fujio K, Matsumoto T, Higashi N, Hashimoto K, Sawaguchi A, Harimoto KI, Nakagawa M, Yamamoto T, Handa M, Watanabe N, Nishi E, Arai F, Nishimura S, Eto K.  Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production.  Cell  2018  174(3):636-648  PubMed ID: 30017246   DOI: 10.1016/j.cell.2018.06.011
11182  Sakai S, Mochizuki K, Qu Y, Mail M, Nakahata M, Taya M.  Peroxidase-catalyzed microextrusion bioprinting of cell-laden hydrogel constructs in vaporized ppm-level hydrogen peroxide.  Biofabrication  2018  10(4):045007  PubMed ID: 30137024   DOI: 10.1088/1758-5090/aadc9e
11138  Fukuda M, Yoshizawa T, Karim MF, Sobuz SU, Korogi W, Kobayasi D, Okanishi H, Tasaki M, Ono K, Sawa T, Sato Y, Chirifu M, Masuda T, Nakamura T, Tanoue H, Nakashima K, Kobashigawa Y, Morioka H, Bober E, Ohtsuki S, Yamagata Y, Ando Y, Oike Y, Araki N, Takeda S, Mizuta H, Yamagata K.  SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix.  Nat Commun  2018  9(1):2833  PubMed ID: 30026585   DOI: 10.1038/s41467-018-05187-4
4059  Yoshida K, Teramachi J, Uchibe K, Ikegame M, Qiu L, Yang D, Okamura H.  Reduction of protein phosphatase 2A Cα promotes in vivo bone formation and adipocyte differentiation.  Mol. Cell. Endocrinol.  2018  470:251-258  PubMed ID: 29128580   DOI: 10.1016/j.mce.2017.11.005
4109  Kiyama R, Nonoyama T, Wada S, Semba S, Kitamura N, Nakajima T, Kurokawa T, Yasuda K, Tanaka S, Gong JP.  Micro patterning of hydroxyapatite by soft lithography on hydrogels for selective osteoconduction.  Acta Biomater  2018    PubMed ID: 30292679   DOI: 10.1016/j.actbio.2018.10.002
4110  Takei H, Edahiro Y, Mano S, Masubuchi N, Mizukami Y, Imai M, Morishita S, Misawa K, Ochiai T, Tsuneda S, Endo H, Nakamura S, Eto K, Ohsaka A, Araki M, Komatsu N.  Skewed megakaryopoiesis in human induced pluripotent stem cell-derived haematopoietic progenitor cells harbouring calreticulin mutations.  Br. J. Haematol.  2018    PubMed ID: 29741776   DOI: 10.1111/bjh.15266
9466  Tetsuya Kawane 1, Xin Qin, Qing Jiang, Toshihiro Miyazaki, Hisato Komori, Carolina Andrea Yoshida, Viviane Keiko Dos Santos Matsuura-Kawata, Chiharu Sakane, Yuki Matsuo, Kazuhiro Nagai, Takafumi Maeno, Yuki Date, Riko Nishimura, Toshihisa Komori   Runx2 Is Required for the Proliferation of Osteoblast Progenitors and Induces Proliferation by Regulating Fgfr2 and Fgfr3  Sci Rep  2018  10;8(1):13551  PubMed ID: 30202094   DOI: 10.1038/s41598-018-31853-0
14902  Kanayama S, Kaito T, Kitaguchi K, Ishiguro H, Hashimoto K, Chijimatsu R, Otsuru S, Takenaka S, Makino T, Sakai Y, Myoui A, Yoshikawa H.  ONO-1301 Enhances in vitro Osteoblast Differentiation and in vivo Bone Formation Induced by Bone Morphogenetic Protein  Spine (Phila Pa 1976)   2018  43(11):E616-E624  PubMed ID: 29016438   DOI: 10.1097/BRS.0000000000002439
9773  Mellati A, Fan CM, Tamayol A, Annabi N, Dai S, Bi J, Jin B, Xian C, Khademhosseini A, Zhang H.  Microengineered 3D cell-laden thermoresponsive hydrogels for mimicking cell morphology and orientation in cartilage tissue engineering.  Biotechnol. Bioeng.  2017  114:217-231  PubMed ID: 27477393   DOI: 10.1002/bit.26061
10343  Khanmohammadi M, Sakai S, Taya M.  Fabrication of single and bundled filament-like tissues using biodegradable hyaluronic acid-based hollow hydrogel fibers.  Int. J. Biol. Macromol.  2017  104:204-212  PubMed ID: 28596006   DOI: 10.1016/j.ijbiomac.2017.06.013
10448  Arai MA, Utsumi T, Yanase N, Fujimatsu T, Ishibashi M.  Efficient Synthesis of Heterocyclic Flavonoids with Hedgehog Signal Inhibitory Activity.  Chem. Pharm. Bull.  2017  65:784-795  PubMed ID: 28768932   DOI: 10.1248/cpb.c17-00305
11004    Migration and Osteogenic Differentiation of Mesenchymal Stem Cells on Titanium with a MicroPatterned Gelatin Matrix  International Journal of Theoretical and Applied Nanotechnology  2017  5:20-26    DOI: 10.11159/ijtan.2017.003
6028  Kawamura F et al  Establishment of induced pluripotent stem cells from normal B cells and inducing AID expression in their differentiation into hematopoietic progenitor cells.  Sci Rep  2017  7(1):1659  PubMed ID: 28490810   DOI: 10.1038/s41598-017-01627-1
6640  Haque Bhuyan MZ, Tamura Y, Sone E, Yoshinari Y, Maeda C, Takahashi M, Tabata Y, Murali R, Waki Y, Aoki K.  The intra-articular injection of RANKL-binding peptides inhibits cartilage degeneration in a murine model of osteoarthritis.  J Pharmacol Sci  2017  134(2):124-130  PubMed ID: 28648299   DOI: 10.1016/j.jphs.2017.05.008
10050  Ha-Eun Yang, Yongjia Li, Akira Nishimura, Huei-Fen Jheng, Ana Yuliana, Ryuji Kitano-Ohue, Wataru Nomura, Nobuyuki Takahashi, Chu-Sook Kim, Rina Yu, Nahoko Kitamura, Si-Bum Park, Shigenobu Kishino, Jun Ogawa, Teruo Kawada, Tsuyoshi Goto  Synthesized Enone Fatty Acids Resembling Metabolites From Gut Microbiota Suppress Macrophage-Mediated Inflammation in Adipocytes  Mol Nutr Food Res  2017  Oct;61(10)  PubMed ID: 28544341   DOI: 10.1002/mnfr.201700064
14049  Tamamura Y, Katsube K, Mera H, Itokazu M, Wakitani S.  Irx3 and Bmp2 regulate mouse mesenchymal cell chondrogenic differentiation in both a Sox9-dependent and -independent manner  J Cell Physiol  2017  232(12):3317-3336  PubMed ID: 28059449   DOI: 10.1002/jcp.25776
14369  Mariko Kawai, Noriyuki Nagaoka, Yasuhiro Yoshida, Kiyoshi Ohura  Cell Population of Mesenchymal Stem Cells on Micro-patterned Titanium  Proceedings of the 2nd World Congress on Recent Advances in Nanotechnology  2017      DOI: 10.11159/nddte17.111
14639  Hirata S, Murata T, Suzuki D, Nakamura S, Jono-Ohnishi R, Hirose H, Sawaguchi A, Nishimura S, Sugimoto N, Eto K.  Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets  Stem Cells Transl Med  2017  6(3):720-730  PubMed ID: 28297575   DOI: 10.5966/sctm.2016-0104
14672  Shubhra QTH, Oyane A, Araki H, Nakamura M, Tsurushima H.  Calcium phosphate nanoparticles prepared from infusion fluids for stem cell transfection: process optimization and cytotoxicity analysis  Biomater Sci  2017  5(5):972-981  PubMed ID: 28211929   DOI: 10.1039/c6bm00870d
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2874  Yano F, Kugimiya F, Ohba S, Ikeda T, Chikuda H, Ogasawara T, Ogata N, Takato T, Nakamura K, Kawaguchi H, Chung UI  The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.  Biochem Biophys Res Commun  2005  333:1300-8  PubMed ID: 15979579   DOI: 10.1016/j.bbrc.2005.06.041
2915  Nobta M, Tsukazaki T, Shibata Y, Xin C, Moriishi T, Sakano S, Shindo H, Yamaguchi A  Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling.  J Biol Chem  2005  280:15842-8  PubMed ID: 15695512   DOI: 10.1074/jbc.M412891200
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2644  Funato N, Ohyama K, Kuroda T, Nakamura M  Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription  J Biol Chem  2003  278:7486-7493  PubMed ID: 12493738   DOI: 10.1074/jbc.M212248200
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5039  Murata T, Sugatani T, Shimizu K, Manganiello VC, Tagawa T.  Effect of the phosphodiesterase 4 inhibitor, rolipram, on retinoic acid-increased alkaline phosphatase activity in the mouse fibroblastic C3H10T1/2 cell line.  Arch Oral Biol  2003  48(1):63-7  PubMed ID: 12615143   DOI: 10.1016/s0003-9969(02)00166-8
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