Back Back
Cell No. : Cell Name
RCB0247 : 10T1/2  update : 2024/01/30
CommentFibroblast-like cells derived from mouse embryo. Can be used for experiments regarding cell transformation.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Terasima, Toyozo
Originator Reznikoff, Catherine A.
Year of deposit 1988
Another name 10T1/2(clone8)
Animal _mouse < Mammals
Strain name C3H
Age at sampling embryo
Tissue embryo
Classification normal
Lifespan infinite
Morphology fibroblast-like
Cellosaurus(Expasy) CVCL_0190
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Culture medium BME (2mM L-Glutamine) + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage cell No 5 x 10 4 cells/60 mm dish
SC frequency Subculture : once/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
SSLP(mouse) OK
Isozyme LD, NP
Chromosome mode 65-81(50) : /75(1),76(1),77(3),78(5),79(12),80(25)/
deposit info
lot info
Reference information Reference 6
User's Publication 186

To topTop
2001  Weintraub H, Davis R, Tapscott S, Thayer M, Krause M, Benezra R, Blackwell, T K, Turner D, Rupp R, Hollenberg S, et al.  The myoD gene family: nodal point during specification of the muscle cell lineage.  Science  1991  251:761-6  PubMed ID: 1846704   DOI: 10.1126/science.1846704
962  Terasima T, Yasukawa M, Kimura M  Radiation-induced transformation of 10T 1/2 mouse cells in the plateau phase: post-irradiation changes and serum dependence.  Gann  1981  72:762-8  PubMed ID: 7327374  
2000  Taylor, S M, Jones, P A  Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine.  Cell  1979  17:771-9  PubMed ID: 90553   DOI: 10.1016/0092-8674(79)90317-9
44  Paranjpe M, del Ande Eaton S, Boone, C W  Neoplasms produced from C3H/10T 1/2 cells attached to plastic plates; saturation density, anchorage dependence and serum requirement of in vitro lines correlated with growth aggressiveness in vivo.  J Cell Physiol  1978  96:63-71  PubMed ID: 659520   DOI: 10.1002/jcp.1040960108
961  Reznikoff, C A, Brankow, D W, Heidelberger C  Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.  Cancer Res  1973  33:3231-8  PubMed ID: 4357355  
176  Reznikoff CA, Bertram JS, Brankow DW, Heidelberger C.  Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division  Cancer Res  1973  33(12):3239-49  PubMed ID: 4796800  

To topTop
User's Publication
21783  Takayanagi SI, Chuganji S, Tanaka M, Wang B, Hasegawa S, Fukumoto K, Wasano N, Kakitani M, Ochiai N, Kawai Y, Ueda T, Ishikawa A, Kurimoto Y, Fukui A, Kamibayashi S, Imai E, Kunisato A, Nozawa H, Kaneko S.  A culture method with berbamine, a plant alkaloid, enhances CAR-T cell efficacy through modulating cellular metabolism.  Commun Biol  2024  7(1):685  PubMed ID: 38834758   DOI: 10.1038/s42003-024-06297-0
21798  Ichiyama-Kobayashi S, Hata K, Wakamori K, Takahata Y, Murakami T, Yamanaka H, Takano H, Yao R, Uzawa N, Nishimura R.  Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development.  JCI Insight  2024  9(11)  PubMed ID: 38855864   DOI: 10.1172/jci.insight.175486
17732  Higa Y, Hiasa M, Tenshin H, Nakaue E, Tanaka M, Kim S, Nakagawa M, Shimizu S, Tanimoto K, Teramachi J, Harada T, Oda A, Oura M, Sogabe K, Hara T, Sumitani R, Maruhashi T, Yamagami H, Endo I, Matsumoto T, Tanaka E, Abe M.  The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2  Antioxidants (Basel)  2023  12(1):133  PubMed ID: 36670994   DOI: 10.3390/antiox12010133
19663  Kotani T, Mubarok W, Hananouchi T, Sakai S.  Horseradish Peroxidase-Mediated Bioprinting via Bioink Gelation by Alternately Extruded Support Material  ACS Biomater Sci Eng  2023  9(10):5804-5812  PubMed ID: 37738620   DOI: 10.1021/acsbiomaterials.3c00996
19690  Liu C, Imai M, Edahiro Y, Mano S, Takei H, Nudejima M, Kurose A, Morishita S, Ando M, Tsuneda S, Araki M, Komatsu N.  Establishment of isogenic induced pluripotent stem cells with or without pathogenic mutation for understanding the pathogenesis of myeloproliferative neoplasms  Exp Hematol  2023  118:12-20  PubMed ID: 36511286   DOI: 10.1016/j.exphem.2022.11.005
19966  Yu Y, Uchida-Fukuhara Y, Weng Y, He Y, Ikegame M, Wang Z, Yoshida K, Okamura H, Qiu L.  Neuropilin 1 (NRP1) Positively Regulates Adipogenic Differentiation in C3H10T1/2 Cells  Int J Mol Sci  2023  24(8):7394  PubMed ID: 37108554   DOI: 10.3390/ijms24087394
17601  Furuya Y, Mera H, Itokazu M, Terai S, Nakamura H, Wakitani S, Yasuda H.  Induction of chondrogenesis with a RANKL-binding peptide, WP9QY, in vitro and in vivo in a rabbit model  Biochem Biophys Res Commun  2022  602:98-104  PubMed ID: 35259590   DOI: 10.1016/j.bbrc.2022.03.019
20079  Miyoshi H, Abo K, Hosoya D, Matsuo K, Utsumi Y.  Effects of mouse fetal liver cell culture density on hematopoietic cell expansion in three-dimensional cocultures with stromal cells.  Int J Artif Organs  2022  391398821996377  PubMed ID: 33611956   DOI: 10.1177/0391398821996377
16273  Sakai S, Kotani T, Harada R, Goto R, Morita T, Bouissil S, Dubessay P, Pierre G, Michaud P, El Boutachfaiti R, Nakahata M, Kojima M, Petit E, Delattre C.  Development of phenol-grafted polyglucuronic acid and its application to extrusion-based bioprinting inks  Carbohydr Polym  2022  277:118820  PubMed ID: 34893237   DOI: 10.1016/j.carbpol.2021.118820
20692  Hayashi Y, Kawabata KC, Tanaka Y, Uehara Y, Mabuchi Y, Murakami K, Nishiyama A, Kiryu S, Yoshioka Y, Ota Y, Sugiyama T, Mikami K, Tamura M, Fukushima T, Asada S, Takeda R, Kunisaki Y, Fukuyama T, Yokoyama K, Uchida T, Hagihara M, Ohno N, Usuki K, Tojo A, Katayama Y, Goyama S, Arai F, Tamura T, Nagasawa T, Ochiya T, Inoue D, Kitamura T.  MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis.  Cell Rep  2022  39(6):110805  PubMed ID: 35545056   DOI: 10.1016/j.celrep.2022.110805
16754  Ishihara K, Kaneyasu M, Fukazawa K, Zhang R, Teramura Y.  Induction of mesenchymal stem cell differentiation by co-culturing with mature cells in double-layered 2-methacryloyloxyethyl phosphorylcholine polymer hydrogel matrices  J Mater Chem B  2022  10(14):2561-2569  PubMed ID: 34878485   DOI: 10.1039/d1tb01817e
16755  Shimohata N, Harada Y, Hayano T.  Proteomic analysis of nascent polypeptide chains that potentially induce translational pausing during elongation  Biosci Biotechnol Biochem  2022  zbac097  PubMed ID: 35749475   DOI: 10.1093/bbb/zbac097
21046  Goto R, Nakahata M, Sakai S.  Phenol-Grafted Alginate Sulfate Hydrogel as an Injectable FGF-2 Carrier.  Gels  2022  8(12)  PubMed ID: 36547342   DOI: 10.3390/gels8120818
14003  Yuzuriha A, Nakamura S, Sugimoto N, Kihara S, Nakagawa M, Yamamoto T, Sekiguchi K, Eto K.  Extracellular laminin regulates hematopoietic potential of pluripotent stem cells through integrin β1-ILK-β-catenin-JUN axis  Stem Cell Res  2021  53:102287.   PubMed ID: 33813173   DOI: 10.1016/j.scr.2021.102287
20202  Matsunami A, Mizuno-Kamiya M, Kawaki H, Takayama E, Ueno K, Ando M, Morimoto-Ito H, Muramatsu Y, Sumitomo S, Kondoh N.  Augmented secretion of IL-1α from mouse oral squamous cell carcinoma (OSCC) cells caused by serum deprivation and hypoxia promotes immune suppressive activity of mesenchymal stromal cells.  J Oral Biosci  2021    PubMed ID: 34153475   DOI: 10.1016/j.job.2021.06.001
16752  Ishii M, Ando J, Yamazaki S, Toyota T, Ohara K, Furukawa Y, Suehara Y, Nakanishi M, Nakashima K, Ohshima K, Nakauchi H, Ando M.  iPSC-Derived Neoantigen-Specific CTL Therapy for Ewing Sarcoma  Cancer Immunol Res  2021  9(10):1175-1186  PubMed ID: 34385178   DOI: 10.1158/2326-6066.CIR-21-0193
12022  Sampilvanjil A, Karasawa T, Yamada N, Komada T, Higashi T, Baatarjav C, Watanabe S, Kamata R, Ohno N, Takahashi M.  Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells.  Am. J. Physiol. Heart Circ. Physiol.  2020    PubMed ID: 31975626   DOI: 10.1152/ajpheart.00559.2019
12066  van Gastel N, Stegen S, Eelen G, Schoors S, Carlier A, Daniëls VW, Baryawno N, Przybylski D, Depypere M, Stiers PJ, Lambrechts D, Van Looveren R, Torrekens S, Sharda A, Agostinis P, Lambrechts D, Maes F, Swinnen JV, Geris L, Van Oosterwyck H, Thienpont B, Carmeliet P, Scadden DT, Carmeliet G.  Lipid availability determines fate of skeletal progenitor cells via SOX9.  Nature  2020    PubMed ID: 32103177   DOI: 10.1038/s41586-020-2050-1
13232  Sakai S, Yoshii A, Sakurai S, Horii K, Nagasuna O.  Silk fibroin nanofibers: a promising ink additive for extrusion three-dimensional bioprinting.  Mater Today Bio  2020    PubMed ID: 33083780   DOI: 10.1016/j.mtbio.2020.100078
13376  Rico P, Rodrigo-Navarro A, Sánchez Pérez L, Salmeron-Sanchez M.  Borax induces osteogenesis by stimulating NaBC1 transporter via activation of BMP pathway.  Commun Biol  2020    PubMed ID: 33247189   DOI: 10.1038/s42003-020-01449-4
13428  J.A.Lenis, P.Rico, J.L. GómezRibelles, M.A.Pacha-Olivenza, M.L.González-Martín, F.J.Bolívar  Structure, morphology, adhesion and in vitro biological evaluation of antibacterial multi-layer HA-Ag/SiO2/TiN/Ti coatings obtained by RF magnetron sputtering for biomedical applications  Materials Science and Engineering:  2020    PubMed ID: 32806245   DOI: 10.1016/j.msec.2020.111268
13857  Gantumur E, Nakahata M, Kojima M, Sakai S.  Extrusion-Based Bioprinting through Glucose-Mediated Enzymatic Hydrogelation  Int J Bioprint  2020  6(1):250  PubMed ID: 32596552   DOI: 10.18063/ijb.v6i1.250
14438  Kazuki Y, Uno N, Abe S, Kajitani N, Kazuki K, Yakura Y, Sawada C, Takata S, Sugawara M, Nagashima Y, Okada A, Hiratsuka M, Osaki M, Ferrari G, Tedesco FS, Nishikawa S, Fukumoto K, Takayanagi SI, Kunisato A, Kaneko S, Oshimura M, Tomizuka K.  Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling  Mol Ther Nucleic Acids  2020  23:629-639  PubMed ID: 33552683   DOI: 10.1016/j.omtn.2020.12.012
11367  Ishijima Y, Ohmori S, Uneme A, Aoki Y, Kobori M, Ohida T, Arai M, Hosaka M, Ohneda K.  The Gata2 repression during 3T3-L1 preadipocyte differentiation is dependent on a rapid decrease in histone acetylation in response to glucocorticoid receptor activation.  Mol. Cell. Endocrinol.  2019    PubMed ID: 30615908   DOI: 10.1016/j.mce.2019.01.002
11397  Gantumur E, Sakai S, Nakahata M, Taya M.  Horseradish peroxidase-catalyzed hydrogelation consuming enzyme-produced hydrogen peroxide in the presence of reducing sugars.  Soft Matter  2019    PubMed ID: 30672948   DOI: 10.1039/c8sm01839a
11582  Numaga-Tomita T, Shimauchi T, Oda S, Tanaka T, Nishiyama K, Nishimura A, Birnbaumer L, Mori Y, Nishida M.  TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential-dependent coupling with PTEN.  FASEB J.  2019    PubMed ID: 31162976   DOI: 10.1096/fj.201802811R
11589  Aoki H, Yamashita M, Hashita T, Nakayama M, Yagi M, Iwao T, Matsunaga T.  Isolation of induced pluripotent stem cell-derived endothelial progenitor cells from sac-like structures.  Biochem. Biophys. Res. Commun.  2019  515(4):672-678  PubMed ID: 31178142   DOI: 10.1016/j.bbrc.2019.05.179
11681  Hiroe Morimoto-Ito, Masako Mizuno-Kamiya, Naoki Umemura, Yoshinori Inagaki, Eiji Takayama, Harumi Kawaki, Yasunori Muramatsu, Shinichiro Sumitomo, Nobuo Kondoh  Immunosuppressive Effect of Mesenchymal Stromal Cells is Enhanced by IL-1α from Oral Squamous Cell Carcinoma Cells  The Open Dentistry Journal  2019  13:221-227    DOI: 10.2174/1874210601913010221
11738  Iriguchi S, Kaneko S.  In Vitro Differentiation of T Cells: From Nonhuman Primate-Induced Pluripotent Stem Cells.  Methods Mol. Biol.  2019    PubMed ID: 31396934   DOI: 10.1007/978-1-4939-9728-2_11
11743  Kawai Y, Kaneko S.  Redifferentiation of Adaptive Naïve-Like CTL from T-Cell-Derived iPSC.  Methods Mol. Biol.  2019    PubMed ID: 31396930   DOI: 10.1007/978-1-4939-9728-2_7
11765  Abe T, Sato T, Yoda T, Hoshi K.  The period circadian clock 2 gene responds to glucocorticoids and regulates osteogenic capacity.  Regen Ther  2019    PubMed ID: 31489343   DOI: 10.1016/j.reth.2019.07.006
11838  Niimi K, Adachi Y, Ishikawa H, Yamaguchi W, Kubota Y, Inagaki S, Furuyama T.  Endothelial specific deletion of FOXO1 alters pericyte coverage in the developing retina.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 31601422   DOI: 10.1016/j.bbrc.2019.10.040
6647  Takahata Y, Nakamura E, Hata K, Wakabayashi M, Murakami T, Wakamori K, Yoshikawa H, Matsuda A, Fukui N, Nishimura R.  Sox4 is involved in osteoarthritic cartilage deterioration through induction of ADAMTS4 and ADAMTS5.  FASEB J  2019  33(1):619-630  PubMed ID: 30016600   DOI: 10.1096/fj.201800259R
6878  Yano F, Ohba S, Murahashi Y, Tanaka S, Saito T, Chung UI.  Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation.  Sci Rep  2019  9(1):7666  PubMed ID: 31113964   DOI: 10.1038/s41598-019-43948-3
6884  Iriguchi S, Kaneko S.  In Vitro Differentiation of T Cells: From Human Embryonic Stem Cells and Induced Pluripotent Stem Cells.  Methods Mol Biol  2019  2048:59-70  PubMed ID: 31396929   DOI: 10.1007/978-1-4939-9728-2_6
6907  Tagaya H, Ishikawa K, Hosokawa Y, Kobayashi S, Ueoka Y, Shimada M, Ohashi Y, Mikami H, Yamamoto M, Ihara T, Kumazawa K, Sugihara K, Goshima N, Watanabe S, Semba K.  A method of producing genetically manipulated mouse mammary gland.  Breast Cancer Res  2019  21(1):1  PubMed ID: 30611295   DOI: 10.1186/s13058-018-1086-8
9893  Zhongren Hu, Shurong Hong, Yu Zhang, Huijing Dai, Shuzhen Lin, Tingyu Yi, Hongmei Zhuang  Down-regulated WDR35 Contributes to Fetal Anomaly via Regulation of Osteogenic Differentiation  Gene  2019  20;697:48-56  PubMed ID: 30790652   DOI: 10.1016/j.gene.2019.02.034
12515  Baba TT, Miyazaki T, Ohara-Nemoto Y, Nemoto TK.  Suppressive effects of N-bisphosphonate in osteoblastic cells mitigated by non-N-bisphosphonate but not by sodium-dependent phosphate cotransporter inhibitor  Cell Biochem Funct  2019  37(6):400-407  PubMed ID: 31328801   DOI: 10.1002/cbf.3418
14881  J.A. Lenis, G. Bejarano, P. Rico, J.L. Gómez Ribelles, F.J. Bolívar  Development of multilayer Hydroxyapatite - Ag/TiN-Ti coatings deposited by radio frequency magnetron sputtering with potential application in the biomedical field  Surface and Coatings Technology  2019  377:124856    DOI: 10.1016/j.surfcoat.2019.06.097
10459  Kusuyama J, Kamisono A, ChangHwan S, Amir MS, Bandow K, Eiraku N, Ohnishi T, Matsuguchi T.  Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities.  J. Cell. Physiol.  2018  233:2549-2559  PubMed ID: 28786489   DOI: 10.1002/jcp.26130
11014    Versatility of hydrogelation by dual-enzymatic reactions with oxidases and peroxidase  Biochemical Engineering Journal  2018  131, 1-8    DOI: 10.1016/j.bej.2017.12.003
11047    Suppressive effect of mesenchymal stromal cells on interferon-γ-producing capability of spleen cells was specifically enhanced through humoral mediator(s) from mouse oral squamous cell carcinoma Sq-1979 Cells In Vitro  Cancer Translational Medicine  2018  4, 9-16    DOI: 10.4103/ctm.ctm_34_17
11132  Ito Y, Nakamura S, Sugimoto N, Shigemori T, Kato Y, Ohno M, Sakuma S, Ito K, Kumon H, Hirose H, Okamoto H, Nogawa M, Iwasaki M, Kihara S, Fujio K, Matsumoto T, Higashi N, Hashimoto K, Sawaguchi A, Harimoto KI, Nakagawa M, Yamamoto T, Handa M, Watanabe N, Nishi E, Arai F, Nishimura S, Eto K.  Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production.  Cell  2018  174(3):636-648  PubMed ID: 30017246   DOI: 10.1016/j.cell.2018.06.011
11182  Sakai S, Mochizuki K, Qu Y, Mail M, Nakahata M, Taya M.  Peroxidase-catalyzed microextrusion bioprinting of cell-laden hydrogel constructs in vaporized ppm-level hydrogen peroxide.  Biofabrication  2018  10(4):045007  PubMed ID: 30137024   DOI: 10.1088/1758-5090/aadc9e
11138  Fukuda M, Yoshizawa T, Karim MF, Sobuz SU, Korogi W, Kobayasi D, Okanishi H, Tasaki M, Ono K, Sawa T, Sato Y, Chirifu M, Masuda T, Nakamura T, Tanoue H, Nakashima K, Kobashigawa Y, Morioka H, Bober E, Ohtsuki S, Yamagata Y, Ando Y, Oike Y, Araki N, Takeda S, Mizuta H, Yamagata K.  SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix.  Nat Commun  2018  9(1):2833  PubMed ID: 30026585   DOI: 10.1038/s41467-018-05187-4
4059  Yoshida K, Teramachi J, Uchibe K, Ikegame M, Qiu L, Yang D, Okamura H.  Reduction of protein phosphatase 2A Cα promotes in vivo bone formation and adipocyte differentiation.  Mol. Cell. Endocrinol.  2018  470:251-258  PubMed ID: 29128580   DOI: 10.1016/j.mce.2017.11.005
4109  Kiyama R, Nonoyama T, Wada S, Semba S, Kitamura N, Nakajima T, Kurokawa T, Yasuda K, Tanaka S, Gong JP.  Micro patterning of hydroxyapatite by soft lithography on hydrogels for selective osteoconduction.  Acta Biomater  2018    PubMed ID: 30292679   DOI: 10.1016/j.actbio.2018.10.002
4110  Takei H, Edahiro Y, Mano S, Masubuchi N, Mizukami Y, Imai M, Morishita S, Misawa K, Ochiai T, Tsuneda S, Endo H, Nakamura S, Eto K, Ohsaka A, Araki M, Komatsu N.  Skewed megakaryopoiesis in human induced pluripotent stem cell-derived haematopoietic progenitor cells harbouring calreticulin mutations.  Br. J. Haematol.  2018    PubMed ID: 29741776   DOI: 10.1111/bjh.15266
9466  Tetsuya Kawane 1, Xin Qin, Qing Jiang, Toshihiro Miyazaki, Hisato Komori, Carolina Andrea Yoshida, Viviane Keiko Dos Santos Matsuura-Kawata, Chiharu Sakane, Yuki Matsuo, Kazuhiro Nagai, Takafumi Maeno, Yuki Date, Riko Nishimura, Toshihisa Komori   Runx2 Is Required for the Proliferation of Osteoblast Progenitors and Induces Proliferation by Regulating Fgfr2 and Fgfr3  Sci Rep  2018  10;8(1):13551  PubMed ID: 30202094   DOI: 10.1038/s41598-018-31853-0
14902  Kanayama S, Kaito T, Kitaguchi K, Ishiguro H, Hashimoto K, Chijimatsu R, Otsuru S, Takenaka S, Makino T, Sakai Y, Myoui A, Yoshikawa H.  ONO-1301 Enhances in vitro Osteoblast Differentiation and in vivo Bone Formation Induced by Bone Morphogenetic Protein  Spine (Phila Pa 1976)   2018  43(11):E616-E624  PubMed ID: 29016438   DOI: 10.1097/BRS.0000000000002439
9773  Mellati A, Fan CM, Tamayol A, Annabi N, Dai S, Bi J, Jin B, Xian C, Khademhosseini A, Zhang H.  Microengineered 3D cell-laden thermoresponsive hydrogels for mimicking cell morphology and orientation in cartilage tissue engineering.  Biotechnol. Bioeng.  2017  114:217-231  PubMed ID: 27477393   DOI: 10.1002/bit.26061
10343  Khanmohammadi M, Sakai S, Taya M.  Fabrication of single and bundled filament-like tissues using biodegradable hyaluronic acid-based hollow hydrogel fibers.  Int. J. Biol. Macromol.  2017  104:204-212  PubMed ID: 28596006   DOI: 10.1016/j.ijbiomac.2017.06.013
10448  Arai MA, Utsumi T, Yanase N, Fujimatsu T, Ishibashi M.  Efficient Synthesis of Heterocyclic Flavonoids with Hedgehog Signal Inhibitory Activity.  Chem. Pharm. Bull.  2017  65:784-795  PubMed ID: 28768932   DOI: 10.1248/cpb.c17-00305
11004    Migration and Osteogenic Differentiation of Mesenchymal Stem Cells on Titanium with a MicroPatterned Gelatin Matrix  International Journal of Theoretical and Applied Nanotechnology  2017  5:20-26    DOI: 10.11159/ijtan.2017.003
6028  Kawamura F et al  Establishment of induced pluripotent stem cells from normal B cells and inducing AID expression in their differentiation into hematopoietic progenitor cells.  Sci Rep  2017  7(1):1659  PubMed ID: 28490810   DOI: 10.1038/s41598-017-01627-1
6640  Haque Bhuyan MZ, Tamura Y, Sone E, Yoshinari Y, Maeda C, Takahashi M, Tabata Y, Murali R, Waki Y, Aoki K.  The intra-articular injection of RANKL-binding peptides inhibits cartilage degeneration in a murine model of osteoarthritis.  J Pharmacol Sci  2017  134(2):124-130  PubMed ID: 28648299   DOI: 10.1016/j.jphs.2017.05.008
10050  Ha-Eun Yang, Yongjia Li, Akira Nishimura, Huei-Fen Jheng, Ana Yuliana, Ryuji Kitano-Ohue, Wataru Nomura, Nobuyuki Takahashi, Chu-Sook Kim, Rina Yu, Nahoko Kitamura, Si-Bum Park, Shigenobu Kishino, Jun Ogawa, Teruo Kawada, Tsuyoshi Goto  Synthesized Enone Fatty Acids Resembling Metabolites From Gut Microbiota Suppress Macrophage-Mediated Inflammation in Adipocytes  Mol Nutr Food Res  2017  Oct;61(10)  PubMed ID: 28544341   DOI: 10.1002/mnfr.201700064
14049  Tamamura Y, Katsube K, Mera H, Itokazu M, Wakitani S.  Irx3 and Bmp2 regulate mouse mesenchymal cell chondrogenic differentiation in both a Sox9-dependent and -independent manner  J Cell Physiol  2017  232(12):3317-3336  PubMed ID: 28059449   DOI: 10.1002/jcp.25776
14369  Mariko Kawai, Noriyuki Nagaoka, Yasuhiro Yoshida, Kiyoshi Ohura  Cell Population of Mesenchymal Stem Cells on Micro-patterned Titanium  Proceedings of the 2nd World Congress on Recent Advances in Nanotechnology  2017      DOI: 10.11159/nddte17.111
14639  Hirata S, Murata T, Suzuki D, Nakamura S, Jono-Ohnishi R, Hirose H, Sawaguchi A, Nishimura S, Sugimoto N, Eto K.  Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets  Stem Cells Transl Med  2017  6(3):720-730  PubMed ID: 28297575   DOI: 10.5966/sctm.2016-0104
14672  Shubhra QTH, Oyane A, Araki H, Nakamura M, Tsurushima H.  Calcium phosphate nanoparticles prepared from infusion fluids for stem cell transfection: process optimization and cytotoxicity analysis  Biomater Sci  2017  5(5):972-981  PubMed ID: 28211929   DOI: 10.1039/c6bm00870d
7086  Hasegawa S, Kitoh H, Ohkawara B, Mishima K, Matsushita M, Masuda A, Ishiguro N, Ohno K.  Tranilast stimulates endochondral ossification by upregulating SOX9 and RUNX2 promoters.  Biochem. Biophys. Res. Commun.  2016  470:356-361  PubMed ID: 26777999   DOI: 10.1016/j.bbrc.2016.01.044
7113  Mellati A, Valizadeh Kiamahalleh M, Dai S, Bi J, Jin B, Zhang H.  Influence of polymer molecular weight on the in vitro cytotoxicity of poly (N-isopropylacrylamide).  Mater Sci Eng C Mater Biol Appl  2016  59:509-513  PubMed ID: 26652402   DOI: 10.1016/j.msec.2015.10.043
9730  Mellati A, Kiamahalleh MV, Madani SH, Dai S, Bi J, Jin B, Zhang H.  Poly(N-isopropylacrylamide) hydrogel/chitosan scaffold hybrid for three-dimensional stem cell culture and cartilage tissue engineering.  J Biomed Mater Res A  2016  104:2764-74  PubMed ID: 27325374   DOI: 10.1002/jbm.a.35810
9786  Sakai S, Nomura K, Mochizuki K, Taya M.  Anchoring PEG-oleate to cell membranes stimulates reactive oxygen species production.  Colloids Surf B Biointerfaces  2016  147:336-342  PubMed ID: 27544656   DOI: 10.1016/j.colsurfb.2016.08.013
9850  Park E, Kim MC, Choi CW, Kim J, Jin HS, Lee R, Lee JW, Park JH, Huh D, Jeong SY.  Effects of Dihydrophaseic Acid 3'-O-β-d-Glucopyranoside Isolated from Lycii radicis Cortex on Osteoblast Differentiation.  Molecules  2016  21(9). pii: E1260  PubMed ID: 27657033   DOI: 10.3390/molecules21091260
9432  Patricia Rico Hayk Mnatsakanyan Matthew J. Dalby Manuel Salmerón‐Sánchez  Material‐Driven Fibronectin Assembly Promotes Maintenance of Mesenchymal Stem Cell Phenotypes  Adv Funct Mater  2016  26:6563–6573    DOI: 10.1002/adfm.201602333
12975  Kaneko S.  In Vitro Generation of Antigen-Specific T Cells from Induced Pluripotent Stem Cells of Antigen-Specific T Cell Origin  Methods Mol Biol  2016  1393:67-73  PubMed ID: 27033216   DOI: 10.1007/978-1-4939-3338-9_6
13478  Saitsu H, Sonoda M, Higashijima T, Shirozu H, Masuda H, Tohyama J, Kato M, Nakashima M, Tsurusaki Y, Mizuguchi T, Miyatake S, Miyake N, Kameyama S, Matsumoto N.  Somatic mutations in GLI3 and OFD1 involved in sonic hedgehog signaling cause hypothalamic hamartoma  Ann Clin Transl Neurol  2016  3(5):356-65  PubMed ID: 27231705   DOI: 10.1002/acn3.300
14126  Moreau T, Evans AL, Vasquez L, Tijssen MR, Yan Y, Trotter MW, Howard D, Colzani M, Arumugam M, Wu WH, Dalby A, Lampela R, Bouet G, Hobbs CM, Pask DC, Payne H, Ponomaryov T, Brill A, Soranzo N, Ouwehand WH, Pedersen RA, Ghevaert C.  Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming  Nat Commun  2016  7:11208  PubMed ID: 27052461   DOI: 10.1038/ncomms11208
7378  Sakai S, Liu Y, Sengoku M, Taya M.  Cell-selective encapsulation in hydrogel sheaths via biospecific identification and biochemical cross-linking.  Biomaterials  2015  53:494-501  PubMed ID: 25890746   DOI: 10.1016/j.biomaterials.2015.02.119
9491  Takashi Nakamura, Masahiro Naruse, Yuta Chiba, Toshihisa Komori, Keiichi Sasaki, Masahiro Iwamoto, Satoshi Fukumoto  Novel Hedgehog Agonists Promote Osteoblast Differentiation in Mesenchymal Stem Cells  J Cell Physiol  2015  230(4):922-9  PubMed ID: 25215620   DOI: 10.1002/jcp.24823
9404  Kaneyoshi Takahashi, Arisa Imai, Masumi Iijima, Nobuo Yoshimoto, Andrés D Maturana, Shun'ichi Kuroda, Tomoaki Niimi  Mapping the Heparin-Binding Site of the Osteoinductive Protein NELL1 by Site-Directed Mutagenesis  BS Lett   2015  589(24 Pt B):4026-32  PubMed ID: 26627376   DOI: 10.1016/j.febslet.2015.11.032
9405  Yoshikazu Mikami, Kiyofumi Yamamoto, Yuko Akiyama, Masayuki Kobayashi, Eri Watanabe, Nobukazu Watanabe, Masatake Asano, Noriyoshi Shimizu, Kazuo Komiyama  Osteogenic Gene Transcription Is Regulated via Gap Junction-Mediated Cell-Cell Communication  Stem Cells Dev  2015  24(2):214-27  PubMed ID: 25137151   DOI: 10.1089/scd.2014.0060
10322  Ryo Nishikiori, Kotaro Watanabe, Koichi Kato  Antibody Arrays for Quality Control of Mesenchymal Stem Cells  ACS Appl Mater Interfaces  2015  7(30):16828-36  PubMed ID: 26172315   DOI: 10.1021/acsami.5b04860
15142  Suttinont C, Mashimo Y, Mie M, Kobatake E.  Delivery of bFGF for Tissue Engineering by Tethering to the ECM  Biomed Res Int  2015  2015:208089  PubMed ID: 26539469   DOI: 10.1155/2015/208089
3999  Hirata N et al  A chemical probe that labels human pluripotent stem cells.  Cell Rep  2014  6(6):1165-1174  PubMed ID: 24613351   DOI: 10.1016/j.celrep.2014.02.006
14698  Nakahara F, Kitaura J, Uchida T, Nishida C, Togami K, Inoue D, Matsukawa T, Kagiyama Y, Enomoto Y, Kawabata KC, Chen-Yi L, Komeno Y, Izawa K, Oki T, Nagae G, Harada Y, Harada H, Otsu M, Aburatani H, Heissig B, Hattori K, Kitamura T.  Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells  Blood  2014  123(25):3932-42  PubMed ID: 24825862   DOI: 10.1182/blood-2013-01-476747
15321  Kitaura Y, Hojo H, Komiyama Y, Takato T, Chung UI, Ohba S.  Gli1 haploinsufficiency leads to decreased bone mass with an uncoupling of bone metabolism in adult mice  PLoS One  2014  9(10):e109597  PubMed ID: 25313900   DOI: 10.1371/journal.pone.0109597
15989  Amir Mellati, Sheng Dai, Jingxiu Bi, Bo Jin, Hu Zhang  A biodegradable thermosensitive hydrogel with tuneable properties for mimicking three-dimensional microenvironments of stem cells  RSC Adv  2014  4:63951-63961    DOI: 10.1039/c4ra12215a
6001  Ogasawara T, Ohba S, Yano F, Kawaguchi H, Chung UI, Saito T, Yonehara Y, Nakatsuka T, Mori Y, Takato T, Hoshi K.  Nanog promotes osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2 by modulating bone morphogenetic protein (BMP) signaling.  J Cell Physiol  2013  228(1):163-71  PubMed ID: 22585661   DOI: 10.1002/jcp.24116
6073  Nakagawa Y, Nakamura S, Nakajima M, Endo H, Dohda T, Takayama N, Nakauchi H, Arai F, Fukuda T, Eto K.  Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell-derived megakaryocytes.  Exp Hematol  2013  41(8):742-8  PubMed ID: 23618622   DOI: 10.1016/j.exphem.2013.04.007
6578  Zanotti S1, Canalis E.  Notch suppresses nuclear factor of activated T cells (NFAT) transactivation and Nfatc1 expression in chondrocytes.  Endocrinology  2013  154(2):762-72  PubMed ID: 23264614   DOI: 10.1210/en.2012-1925
6572  Kan A, Ikeda T, Fukai A, Nakagawa T, Nakamura K, Chung UI, Kawaguchi H, Tabin CJ.  SOX11 contributes to the regulation of GDF5 in joint maintenance.  BMC Dev Biol  2013  13:4  PubMed ID: 23356643   DOI: 10.1186/1471-213X-13-4
6575  Hata K, Takashima R, Amano K, Ono K, Nakanishi M, Yoshida M, Wakabayashi M, Matsuda A, Maeda Y, Suzuki Y, Sugano S, Whitson RH, Nishimura R, Yoneda T.  Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes.  Nat Commun  2013  4:2850  PubMed ID: 24276541   DOI: 10.1038/ncomms3850
9279  Yujiro Maeda, Hironori Hojo, Nobuyuki Shimohata, Sungjin Choi, Kenichi Yamamoto, Tsuyoshi Takato, Ung-il Chung, Shinsuke Ohba  Bone Healing by Sterilizable Calcium Phosphate Tetrapods Eluting Osteogenic Molecules  Biomaterials  2013  34(22):5530-7  PubMed ID: 23623228   DOI: 10.1016/j.biomaterials.2013.03.089
13742  Kishimoto KN, Itoi E.  Lithium chloride enhances cathepsin H expression and BMP-4 degradation in C3H10T1/2 cells  Biomed Res Int  2013  2013:143742  PubMed ID: 24312905   DOI: 10.1155/2013/143742
15941  Sakai S, Liu Y, Mah EJ, Taya M.  Horseradish peroxidase/catalase-mediated cell-laden alginate-based hydrogel tube production in two-phase coaxial flow of aqueous solutions for filament-like tissues fabrication  Biofabrication   2013  5(1):015012.  PubMed ID: 23319520   DOI: 10.1088/1758-5082/5/1/015012
5991  Takayama N, Eto K.  In vitro generation of megakaryocytes and platelets from human embryonic stem cells and induced pluripotent stem cells.  Methods Mol Biol  2012  788:205-17  PubMed ID: 22130710   DOI: 10.1007/978-1-61779-307-3_15
6012  Zhao WH1, Hu ZQ.  Up-regulation of IL-33 expression in various types of murine cells by IL-3 and IL-4.  Cytokine  2012  58(2):267-73  PubMed ID: 22370606   DOI: 10.1016/j.cyto.2012.01.019
5318  Gu S, Boyer TG, Naski MC.  Basic helix-loop-helix transcription factor Twist1 inhibits transactivator function of master chondrogenic regulator Sox9.  J Biol Chem.   2012  287(25):21082-92  PubMed ID: 22532563   DOI: 10.1074/jbc.M111.328567
6554  Oze H, Hirao M, Ebina K, Shi K, Kawato Y, Kaneshiro S, Yoshikawa H, Hashimoto J.  Impact of medium volume and oxygen concentration in the incubator on pericellular oxygen concentration and differentiation of murine chondrogenic cell culture.  In Vitro Cell Dev Biol Anim  2012  48(2):123-30  PubMed ID: 22259015   DOI: 10.1007/s11626-011-9479-3
15979  Zheyu Shen, Jingxiu Bi, Bingyang Shi, Dzuy Nguyen, Cory J. Xian, Hu Zhang, Sheng Dai  Exploring thermal reversible hydrogels for stem cell expansion in three-dimensions  Soft Matter  2012  8:7250    DOI: 10.1039/c2sm25407g
7632  Kawato Y, Hirao M, Ebina K, Tamai N, Shi K, Hashimoto J, Yoshikawa H, Myoui A.  Nkx3.2-induced suppression of Runx2 is a crucial mediator of hypoxia-dependent maintenance of chondrocyte phenotypes.  Biochem. Biophys. Res. Commun.  2011  416:205-10  PubMed ID: 22093831   DOI: 10.1016/j.bbrc.2011.11.026
7688  Hatakeyama Y, Hatakeyama J, Takahashi A, Oka K, Tsuruga E, Inai T, Sawa Y.  The effect of valproic Acid on mesenchymal pluripotent cell proliferation and differentiation in extracellular matrices.  Drug Target Insights  2011  5:1-9  PubMed ID: 21904447   DOI: 10.4137/DTI.S6534
7804  Yamagishi N, Yokota M, Yasuda K, Saito Y, Nagata K, Hatayama T.  Characterization of stress sensitivity and chaperone activity of Hsp105 in mammalian cells.  Biochem. Biophys. Res. Commun.  2011  409:90-5  PubMed ID: 21557931   DOI: 10.1016/j.bbrc.2011.04.114
7855  Shimizu T, Tanaka T, Iso T, Matsui H, Ooyama Y, Kawai-Kowase K, Arai M, Kurabayashi M.  Notch signaling pathway enhances bone morphogenetic protein 2 (BMP2) responsiveness of Msx2 gene to induce osteogenic differentiation and mineralization of vascular smooth muscle cells.  J. Biol. Chem.  2011  286:19138-48  PubMed ID: 21471203   DOI: 10.1074/jbc.M110.175786
7912  Amano K, Hata K, Muramatsu S, Wakabayashi M, Takigawa Y, Ono K, Nakanishi M, Takashima R, Kogo M, Matsuda A, Nishimura R, Yoneda T.  Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription.  Mol. Biol. Cell  2011  22:1300-11  PubMed ID: 21346191   DOI: 10.1091/mbc.E10-07-0566
8035  Mikami Y, Ishii Y, Watanabe N, Shirakawa T, Suzuki S, Irie S, Isokawa K, Honda MJ.  CD271/p75(NTR) inhibits the differentiation of mesenchymal stem cells into osteogenic, adipogenic, chondrogenic, and myogenic lineages.  Stem Cells Dev.  2011  20:901-13  PubMed ID: 21142793   DOI: 10.1089/scd.2010.0299
8153  Takarada-Iemata M, Takarada T, Nakamura Y, Nakatani E, Hori O, Yoneda Y.  Glutamate preferentially suppresses osteoblastogenesis than adipogenesis through the cystine/glutamate antiporter in mesenchymal stem cells.  J. Cell. Physiol.  2011  226:652-65  PubMed ID: 20717926   DOI: 10.1002/jcp.22390
18896  Ninomiya T, Hosoya A, Hiraga T, Koide M, Yamaguchi K, Oida H, Arai Y, Sahara N, Nakamura H, Ozawa H.  Prostaglandin E(2) receptor EP(4)-selective agonist (ONO-4819) increases bone formation by modulating mesenchymal cell differentiation  Eur J Pharmacol  2011  650(1):396-402  PubMed ID: 20969852   DOI: 10.1016/j.ejphar.2010.10.021
5990  Kikuchi Y, Kume A, Urabe M, Mizukami H, Suzuki T, Ozaki K, Nagai T, Ozawa K.  Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells.  J Stem Cells Regen Med  2011  7(2):61-8  PubMed ID: 24693172   DOI: 10.46582/jsrm.0702010
8358  Zhang W, Tsurushima H, Oyane A, Yazaki Y, Sogo Y, Ito A, Matsumura A.  BMP-2 gene-fibronectin-apatite composite layer enhances bone formation.  J Biomed Sci  2011  18:62  PubMed ID: 21859498   DOI: 10.1186/1423-0127-18-62
8553  Neil A Mabbott, J Kenneth Baillie, Atsushi Kobayashi, David S Donaldson, Hitoshi Ohmori, Sun-Ok Yoon, Arnold S Freedman, Tom C Freeman, Kim M Summers  Expression of Mesenchyme-Specific Gene Signatures by Follicular Dendritic Cells: Insights From the Meta-Analysis of Microarray Data From Multiple Mouse Cell Populations  Immunology   2011  133(4):482-98  PubMed ID: 21635249   DOI: 10.1111/j.1365-2567.2011.03461.x
16753  Arai MA, Tateno C, Koyano T, Kowithayakorn T, Kawabe S, Ishibashi M.  New hedgehog/GLI-signaling inhibitors from Adenium obesum  Org Biomol Chem  2011  9(4):1133-9  PubMed ID: 21170436   DOI: 10.1039/c0ob00677g
8179  Kawai S, Abiko Y, Amano A.  Odd-skipped related 2 regulates genes related to proliferation and development.  Biochem. Biophys. Res. Commun.  2010  398:184-90  PubMed ID: 20599744   DOI: 10.1016/j.bbrc.2010.06.054
8272  Kawai S, Amano A.  Odd-skipped related 2 is epigenetically regulated in cellular quiescence.  Biochem. Biophys. Res. Commun.  2010  396:831-6  PubMed ID: 20450884   DOI: 10.1016/j.bbrc.2010.04.159
8407  Mikami Y, Asano M, Honda MJ, Takagi M.  Bone morphogenetic protein 2 and dexamethasone synergistically increase alkaline phosphatase levels through JAK/STAT signaling in C3H10T1/2 cells.  J. Cell. Physiol.  2010  223:123-33  PubMed ID: 20039267   DOI: 10.1002/jcp.22017
4679  Takigawa Y, Hata K, Muramatsu S, Amano K, Ono K, Wakabayashi M, Matsuda A, Takada K, Nishimura R, Yoneda T.  The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9.  J Cell Sci  2010  123(Pt 21):3780-8  PubMed ID: 20940257   DOI: 10.1242/jcs.071373
8266  Takeuchi K, Abe M, Hiasa M, Oda A, Amou H, Kido S, Harada T, Tanaka O, Miki H, Nakamura S, Nakano A, Kagawa K, Yata K, Ozaki S, Matsumoto T.  Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth.  PLoS One  2010  5(3):e9870  PubMed ID: 20360846   DOI: 10.1371/journal.pone.0009870
8562  Yuasa K, Masuda T, Yoshikawa C, Nagahama M, Matsuda Y, Tsuji A.  Subtilisin-like proprotein convertase PACE4 is required for skeletal muscle differentiation.  J. Biochem.  2009  146:407-15  PubMed ID: 19520771   DOI: 10.1093/jb/mvp090
8595  Osawa K, Okubo Y, Nakao K, Koyama N, Bessho K.  Osteoinduction by microbubble-enhanced transcutaneous sonoporation of human bone morphogenetic protein-2.  J Gene Med  2009  11:633-41  PubMed ID: 19396932   DOI: 10.1002/jgm.1331
8725  Takahata Y, Takarada T, Iemata M, Yamamoto T, Nakamura Y, Kodama A, Yoneda Y.  Functional expression of beta2 adrenergic receptors responsible for protection against oxidative stress through promotion of glutathione synthesis after Nrf2 upregulation in undifferentiated mesenchymal C3H10T1/2 stem cells.  J. Cell. Physiol.  2009  218:268-75  PubMed ID: 18814142   DOI: 10.1002/jcp.21594
19094  Kadouchi I, Sakamoto K, Tangjiao L, Murakami T, Kobayashi E, Hoshino Y, Yamaguchi A.  Latexin is involved in bone morphogenetic protein-2-induced chondrocyte differentiation  Biochem Biophys Res Commun  2009  378(3):600-4  PubMed ID: 19059214   DOI: 10.1016/j.bbrc.2008.11.111
6131  Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H.  The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells.  Stem Cells  2009  27(5):1120-9  PubMed ID: 19415782   DOI: 10.1002/stem.42
6534  Yanagino T, Yuasa K, Nagahama M, Matsuda Y, Tsuji A.  Transcriptional regulation of fibrillin-2 gene by E2F family members in chondrocyte differentiation.  J Cell Biochem  2009  106(4):580-8  PubMed ID: 19142862   DOI: 10.1002/jcb.22029
12195  Taro Ishigaki, Kazuhiro Sudo, Takashi Hiroyama, Kenichi Miharada, Haruhiko Ninomiya, Shigeru Chiba, Toshiro Nagasawa, Yukio Nakamura  Human hematopoietic stem cells can survive in vitro for several months  Adv Hematol  2009  2009:936761  PubMed ID: 19960048   DOI: 10.1155/2009/936761
15633  Ono Y, Gnocchi VF, Zammit PS, Nagatomi R.  Presenilin-1 acts via Id1 to regulate the function of muscle satellite cells in a gamma-secretase-independent manner  J Cell Sci  2009  122(Pt 24):4427-38  PubMed ID: 19920078   DOI: 10.1242/jcs.049742
18337  Kazama T, Fujie M, Endo T, Kano K.  Mature adipocyte-derived dedifferentiated fat cells can transdifferentiate into skeletal myocytes in vitro  Biochem Biophys Res Commun  2008  377(3):780-5  PubMed ID: 18938140   DOI: 10.1016/j.bbrc.2008.10.046
18413  Amano K, Ichida F, Sugita A, Hata K, Wada M, Takigawa Y, Nakanishi M, Kogo M, Nishimura R, Yoneda T.  MSX2 stimulates chondrocyte maturation by controlling Ihh expression  J Biol Chem  2008  283(43):29513-21  PubMed ID: 18682398   DOI: 10.1074/jbc.M803681200
18417  Hosoya T, Arai MA, Koyano T, Kowithayakorn T, Ishibashi M.  Naturally occurring small-molecule inhibitors of hedgehog/GLI-mediated transcription  Chembiochem  2008  9(7):1082-92  PubMed ID: 18357592   DOI: 10.1002/cbic.200700511
8727  Yamauchi M, Kawai S, Kato T, Ooshima T, Amano A.  Odd-skipped related 1 gene expression is regulated by Runx2 and Ikzf1 transcription factors.  Gene  2008  426:81-90  PubMed ID: 18804520   DOI: 10.1016/j.gene.2008.08.015
6519  Hata K, Nishimura R, Muramatsu S, Matsuda A, Matsubara T, Amano K, Ikeda F, Harley VR, Yoneda T.  Paraspeckle protein p54nrb links Sox9-mediated transcription with RNA processing during chondrogenesis in mice.  J Clin Invest  2008  118(9):3098-108  PubMed ID: 18677406   DOI: 10.1172/JCI31373
7730  Zhao J, Ohba S, Shinkai M, Chung UI, Nagamune T.  Icariin induces osteogenic differentiation in vitro in a BMP- and Runx2-dependent manner.  Biochem Biophys Res Commun  2008  369(2):444-8  PubMed ID: 18295595   DOI: 10.1016/j.bbrc.2008.02.054
7919  Nomura-Furuwatari C, Wakitani S, Hashimoto Y, Imai Y, Ohta Y, Nakagawa K, Nakao Y, Takayama K, Manaka T, Takaoka K.  Expression profiles of phosphodiesterase 4D splicing variants in osteoblastic cells.  J Bone Miner Metab  2008  26(2):152-8  PubMed ID: 18301971   DOI: 10.1007/s00774-007-0803-7
7927  Miyawaki J, Kamei S, Sakayama K, Yamamoto H, Masuno H.  4-tert-octylphenol regulates the differentiation of C3H10T1/2 cells into osteoblast and adipocyte lineages.  Toxicol Sci  2008  102(1):82-8  PubMed ID: 18065773   DOI: 10.1093/toxsci/kfm296
10904  Naoya Takayama, Hidekazu Nishikii, Joichi Usui, Hiroko Tsukui, Akira Sawaguchi, Takashi Hiroyama, Koji Eto, Hiromitsu Nakauchi  Generation of Functional Platelets From Human Embryonic Stem Cells in Vitro via ES-sacs, VEGF-promoted Structures That Concentrate Hematopoietic Progenitors  Blood  2008  111(11):5298-306  PubMed ID: 18388179   DOI: 10.1182/blood-2007-10-117622
8803  Kawai S, Yamauchi M, Wakisaka S, Ooshima T, Amano A.  Zinc-finger transcription factor odd-skipped related 2 is one of the regulators in osteoblast proliferation and bone formation.  J. Bone Miner. Res.  2007  22:1362-72  PubMed ID: 17547533   DOI: 10.1359/jbmr.070602
18675  Hiraga T, Kizaka-Kondoh S, Hirota K, Hiraoka M, Yoneda T.  Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer  Cancer Res  2007  67(9):4157-63  PubMed ID: 17483326   DOI: 10.1158/0008-5472.CAN-06-2355
18886  Zeng L, Kizaka-Kondoh S, Itasaka S, Xie X, Inoue M, Tanimoto K, Shibuya K, Hiraoka M.  Hypoxia inducible factor-1 influences sensitivity to paclitaxel of human lung cancer cell lines under normoxic conditions  Cancer Sci  2007  98(9):1394-401.  PubMed ID: 17608771   DOI: 10.1111/j.1349-7006.2007.00537.x
3584  Muramatsu S, Wakabayashi M, Ohno T, Amano K, Ooishi R, Sugahara T, Shiojiri S, Tashiro K, Suzuki Y, Nishimura R, Kuhara S, Sugano S, Yoneda T, Matsuda A.  Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation.  J Biol Chem  2007  282(44):32158-67  PubMed ID: 17804410   DOI: 10.1074/jbc.M706158200
7246  Maruyama Z, Yoshida CA, Furuichi T, Amizuka N, Ito M, Fukuyama R, Miyazaki T, Kitaura H, Nakamura K, Fujita T, Kanatani N, Moriishi T, Yamana K, Liu W, Kawaguchi H, Nakamura K, Komori T.  Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency.  Dev Dyn  2007  236(7):1876-90  PubMed ID: 17497678   DOI: 10.1002/dvdy.21187
7390  Iemata M, Takarada T, Hinoi E, Taniura H, Yoneda Y.  Suppression by glutamate of proliferative activity through glutathione depletion mediated by the cystine/glutamate antiporter in mesenchymal C3H10T1/2 stem cells.  J Cell Physiol  2007  213(3):721-9  PubMed ID: 17520696   DOI: 10.1002/jcp.21145
13955  Nakagawa K, Imai Y, Ohta Y, Takaoka K.  Prostaglandin E2 EP4 agonist (ONO-4819) accelerates BMP-induced osteoblastic differentiation  Bone  2007  41(4):543-8  PubMed ID: 17681894   DOI: 10.1016/j.bone.2007.06.013
3357  Hiroyama, Takashi, Miharada, Kenichi, Aoki, Naoko, Fujioka, Tsuyoshi, Sudo, Kazuhiro, Danjo, Inaho, Nagasawa, Toshiro, Nakamura, Yukio  Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells.  Exp Hematol  2006  34:760-9  PubMed ID: 16728281   DOI: 10.1016/j.exphem.2006.03.004
19092  Yamagishi N, Tokunaga S, Ishihara K, Saito Y, Hatayama T.  The phenylic hydroxyl group is essential for the induction of stress response by sodium salicylate  Biochem Biophys Res Commun  2006  350(1):131-7  PubMed ID: 16996033   DOI: 10.1016/j.bbrc.2006.09.008
6998  Kawai S, Kato T, Sato M, Amano A.  Odd-skipped related 2 gene transcription is regulated by CCAAT enhancer-binding protein delta in mesenchymal C3H10T1/2 cells.  Genes Cells  2006  11(2):163-75  PubMed ID: 16436053   DOI: 10.1111/j.1365-2443.2006.00929.x
7004  Hirao M, Tamai N, Tsumaki N, Yoshikawa H, Myoui A.  Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification.  J Biol Chem  2006  281(41):31079-92  PubMed ID: 16905540   DOI: 10.1074/jbc.M602296200
12831  Uozumi Y, Ito T, Hoshino Y, Mohri T, Maeda M, Takahashi K, Fujio Y, Azuma J.  Myogenic differentiation induces taurine transporter in association with taurine-mediated cytoprotection in skeletal muscles  Biochem J  2006  394(Pt 3):699-706  PubMed ID: 16318624   DOI: 10.1042/BJ20051303
3159  Miharada, Ken-ichi, Hiroyama, Takashi, Sudo, Kazuhiro, Nagasawa, Toshiro, Nakamura, Yukio  Lipocalin 2 functions as a negative regulator of red blood cell production in an autocrine fashion.  FASEB J  2005  19:1881-3  PubMed ID: 16157692   DOI: 10.1096/fj.05-3809fje
2874  Yano F, Kugimiya F, Ohba S, Ikeda T, Chikuda H, Ogasawara T, Ogata N, Takato T, Nakamura K, Kawaguchi H, Chung UI  The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.  Biochem Biophys Res Commun  2005  333:1300-8  PubMed ID: 15979579   DOI: 10.1016/j.bbrc.2005.06.041
2915  Nobta M, Tsukazaki T, Shibata Y, Xin C, Moriishi T, Sakano S, Shindo H, Yamaguchi A  Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling.  J Biol Chem  2005  280:15842-8  PubMed ID: 15695512   DOI: 10.1074/jbc.M412891200
2936  Kawai S, Kato T, Inaba H, Okahashi N, Amano A  Odd-skipped related 2 splicing variants show opposite transcriptional activity.  Biochem Biophys Res Commun  2005  328:306-11  PubMed ID: 15670784   DOI: 10.1016/j.bbrc.2004.12.173
3183  Hata, Kenji, Nishimura, Riko, Ueda, Mio, Ikeda, Fumiyo, Matsubara, Takuma, Ichida, Fumitaka, Hisada, Kunihiro, Nokubi, Takashi, Yamaguchi, Akira, Yoneda, Toshiyuki  A CCAAT/enhancer binding protein beta isoform, liver-enriched inhibitory protein, regulates commitment of osteoblasts and adipocytes.  Mol Cell Biol  2005  25:1971-9  PubMed ID: 15713650   DOI: 10.1128/MCB.25.5.1971-1979.2005
6876  Imai Y, Terai H, Nomura-Furuwatari C, Mizuno S, Matsumoto K, Nakamura T, Takaoka K.  Hepatocyte growth factor contributes to fracture repair by upregulating the expression of BMP receptors.  J Bone Miner Res  2005  20(10):1723-30  PubMed ID: 16160730   DOI: 10.1359/JBMR.050607
3158  Nishimura, Haruki, Nishimura, Masahiro, Oda, Ryo, Yamanaka, Katsuyuki, Matsubara, Takehiro, Ozaki, Yoshie, Sekiya, Kensuke, Hamada, Taizo, Kato, Yukio  Lectins induce resistance to proteases and/or mechanical stimulus in all examined cells--including bone marrow mesenchymal stem cells--on various scaffolds.  Exp Cell Res  2004  295:119-27  PubMed ID: 15051495   DOI: 10.1016/j.yexcr.2003.12.018
2893  Ichida, Fumitaka, Nishimura, Riko, Hata, Kenji, Matsubara, Takuma, Ikeda, Fumiyo, Hisada, Kunihiro, Yatani, Hirofumi, Cao, Xu, Komori, Toshihisa, Yamaguchi, Akira, Yoneda, Toshiyuki  Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation.  J Biol Chem  2004  279:34015-22  PubMed ID: 15175325   DOI: 10.1074/jbc.M403621200
2899  Fujita, Takashi, Azuma, Yasutaka, Fukuyama, Ryo, Hattori, Yuji, Yoshida, Carolina, Koida, Masao, Ogita, Kiyokazu, Komori, Toshihisa  Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling.  J Cell Biol  2004  166:85-95  PubMed ID: 15226309   DOI: 10.1083/jcb.200401138
3343  Ishihara, Keiichi, Yamagishi, Nobuyuki, Hatayama, Takumi  Suppression of heat- and polyglutamine-induced cytotoxicity by nonsteroidal anti-inflammatory drugs.  Eur J Biochem  2004  271:4552-8  PubMed ID: 15560796   DOI: 10.1111/j.1432-1033.2004.04419.x
6714  Date T, Doiguchi Y, Nobuta M, Shindo H.  Bone morphogenetic protein-2 induces differentiation of multipotent C3H10T1/2 cells into osteoblasts, chondrocytes, and adipocytes in vivo and in vitro.  J Orthop Sci  2004  9(5):503-8  PubMed ID: 15449126   DOI: 10.1007/s00776-004-0815-2
2644  Funato N, Ohyama K, Kuroda T, Nakamura M  Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription  J Biol Chem  2003  278:7486-7493  PubMed ID: 12493738   DOI: 10.1074/jbc.M212248200
2635  Hata K, Nishimura R, Ikeda F, Yamashita K, Matsubara T, Nokubi T, Yoneda T  Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor gamma during bone morphogenetic protein 2-induced adipogenesis.  Mol Biol Cell  2003  14:545-55  PubMed ID: 12589053   DOI: 10.1091/mbc.E02-06-0356
4944  Oda R, Suardita K, Fujimoto K, Pan H, Yan W, Shimazu A, Shintani H, Kato Y.  Anti-membrane-bound transferrin-like protein antibodies induce cell-shape change and chondrocyte differentiation in the presence or absence of concanavalin A.  J Cell Sci  2003  116(Pt 10):2029-38  PubMed ID: 12679380   DOI: 10.1242/jcs.00393
5039  Murata T, Sugatani T, Shimizu K, Manganiello VC, Tagawa T.  Effect of the phosphodiesterase 4 inhibitor, rolipram, on retinoic acid-increased alkaline phosphatase activity in the mouse fibroblastic C3H10T1/2 cell line.  Arch Oral Biol  2003  48(1):63-7  PubMed ID: 12615143   DOI: 10.1016/s0003-9969(02)00166-8
3557  Tezuka K, Yasuda M, Watanabe N, Morimura N, Kuroda K, Miyatani S, Hozumi N.  Stimulation of osteoblastic cell differentiation by Notch.  J Bone Miner Res  2002  17(2):231-9  PubMed ID: 11811553   DOI: 10.1359/jbmr.2002.17.2.231
3560  Fujita T, Meguro T, Fukuyama R, Nakamuta H, Koida M.  New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP.  J Biol Chem  2002  277(25):22191-200  PubMed ID: 11956184   DOI: 10.1074/jbc.M110364200
3566  Suardita K, Fujimoto K, Oda R, Shimazu A, Miyazaki K, Kawamoto T, Kato Y.  Effects of overexpression of membrane-bound transferrin-like protein (MTf) on chondrogenic differentiation in Vitro.  J Biol Chem  2002  277(50):48579-86  PubMed ID: 12374788   DOI: 10.1074/jbc.M209243200
6691  Yuasa T, Kataoka H, Kinto N, Iwamoto M, Enomoto-Iwamoto M, Iemura S, Ueno N, Shibata Y, Kurosawa H, Yamaguchi A.  Sonic hedgehog is involved in osteoblast differentiation by cooperating with BMP-2.  J Cell Physiol  2002  193(2):225-32  PubMed ID: 12385000   DOI: 10.1002/jcp.10166
6699  Tang L, Ebara S, Kawasaki S, Wakabayashi S, Nikaido T, Takaoka K.  FK506 enhanced osteoblastic differentiation in mesenchymal cells.  Cell Biol Int  2002  26(1):75-84  PubMed ID: 11779223   DOI: 10.1006/cbir.2001.0812
6703  Katagiri T, Imada M, Yanai T, Suda T, Takahashi N, Kamijo R.  Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis.  Genes Cells  2002  7(9):949-60  PubMed ID: 12296825   DOI: 10.1046/j.1365-2443.2002.00573.x
2480  Maeda T, Abe M, Kurisu K, Jikko A, Furukawa S  Molecular cloning and characterization of a novel gene, CORS26, encoding a putative secretory protein and its possible involvement in skeletal development.  J Biol Chem  2001  276:3628-34  PubMed ID: 11071891   DOI: 10.1074/jbc.M007898200
6157  Muramatsu M, Hanazono Y, Ogasawara Y, Okada T, Mizukami H, Kume A, Mizoguchi H, Ozawa K.  Reversible integration of the dominant negative retinoid receptor gene for ex vivo expansion of hematopoietic stem/progenitor cells.  Biochem Biophys Res Commun  2001  285(4):891-6  PubMed ID: 11467834   DOI: 10.1006/bbrc.2001.5264
3542  Ito H, Akiyama H, Iguchi H, Iyama K, Miyamoto M, Ohsawa K, Nakamura T.  Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilage.  J Biol Chem  2001  276(26):24023-9  PubMed ID: 11292829   DOI: 10.1074/jbc.M100861200
6659  Tamura S, Kataoka H, Matsui Y, Shionoya Y, Ohno K, Michi KI, Takahashi K, Yamaguchi A.  The effects of transplantation of osteoblastic cells with bone morphogenetic protein (BMP)/carrier complex on bone repair.  Bone  2001  29(2):169-75  PubMed ID: 11502479   DOI: 10.1016/s8756-3282(01)00498-7
16961  Hamada T, Ui-Tei K, Imaki J, Miyata Y.  Molecular cloning of SCDGF-B, a novel growth factor homologous to SCDGF/PDGF-C/fallotein  Biochem Biophys Res Commun  2001  280(3):733-7  PubMed ID: 11162582   DOI: 10.1006/bbrc.2000.4187
3989  Yoshimasa FUJIMAKI  The Role of Recombinant Human Bone Morphogenetic Protein 2 (rhBMP-2) in the Differentiation of Osteoblasts and Chondrocytes  The Showa University Journal of Medical Sciences  2000  12:39-49    DOI: 10.15369/sujms1989.12.39
3997  Enomoto-Iwamoto M, Nakamura T, Aikawa T, Higuchi Y, Yuasa T, Yamaguchi A, Nohno T, Noji S, Matsuya T, Kurisu K, Koyama E, Pacifici M, Iwamoto M.  Hedgehog proteins stimulate chondrogenic cell differentiation and cartilage formation.  J Bone Miner Res  2000  15(9):1659-68  PubMed ID: 10976986   DOI: 10.1359/jbmr.2000.15.9.1659
3540  Kusanagi K, Inoue H, Ishidou Y, Mishima HK, Kawabata M, Miyazono K.  Characterization of a bone morphogenetic protein-responsive Smad-binding element.  Mol Biol Cell  2000  11(2):555-65  PubMed ID: 10679014   DOI: 10.1091/mbc.11.2.555
17277  Nakane T, Inada Y, Ito F, Itoh N, Tazawa S, Chiba S.  Cloning and expression of mouse deafness dystonia peptide 1 cDNA  Biochem Biophys Res Commun  2000  273(2):759-64  PubMed ID: 10873677   DOI: 10.1006/bbrc.2000.3004
3969  Akiyama H1, Hiraki Y, Noda M, Shigeno C, Ito H, Nakamura T.  Molecular cloning and biological activity of a novel Ha-Ras suppressor gene predominantly expressed in skeletal muscle, heart, brain, and bone marrow by differential display using clonal mouse EC cells, ATDC5.  J Biol Chem  1999.  274(45):32192-7  PubMed ID: 10542256   DOI: 10.1074/jbc.274.45.32192
4833  Matsuda KM, Kume A, Ueda Y, Urabe M, Hasegawa M, Ozawa K.  Development of a modified selective amplifier gene for hematopoietic stem cell gene therapy  Gene Ther  1999  6(6):1038-44  PubMed ID: 10455406   DOI: 10.1038/
3968  Tamura M, Noda M.  Identification of DERMO-1 as a member of helix-loop-helix type transcription factors expressed in osteoblastic cells.  J Cell Biochem  1999  72(2):167-76  PubMed ID: 10022499   DOI: 10.1002/(sici)1097-4644(19990201)72:2<167::aid-jcb1>;2-3
2445  Harada H, Tagashira S, Fujiwara M, Ogawa S, Katsumata T, Yamaguchi A, Komori T, Nakatsuka M.  Cbfa1 isoforms exert functional differences in osteoblast differentiation  J Biol Chem  1999  274(11):6972-8.  PubMed ID: 10066751   DOI: 10.1074/jbc.274.11.6972
3921  Kobayashi T, Sugimoto T, Kanzawa M, Chihara K.  Identification of an enhancer sequence in 5'-flanking region of 1A exon of mouse liver/bone/kidney-type alkaline phosphatase gene.  Biochem Mol Biol Int  1998  44(4):683-91  PubMed ID: 9584982   DOI: 10.1080/15216549800201732
3922  Yanaka N, Akatsuka H, Kawai E, Omori K.  1,25-Dihydroxyvitamin D3 upregulates natriuretic peptide receptor-C expression in mouse osteoblasts.  Am J Physiol  1998  275(6):E965-73  PubMed ID: 9843738   DOI: 10.1152/ajpendo.1998.275.6.E965
3546  Hideyoshi Kashimoto, Riko Kitazawa, Sakan Maeda, Kosaku Mizuno, Sohei Kitazawa  Modulation of Osteonectin and Osteopontin Expression during Fracture Healing of Mouse Bone Tissue  ACTA HISTOCHEMICA ET CYTOCHEMICA  1998  31:501-508    DOI: 10.1267/ahc.31.501
18087  Kobayashi T, Sugimoto T, Saijoh K, Fukase M, Chihara K.  Cloning of mouse diastrophic dysplasia sulfate transporter gene induced during osteoblast differentiation by bone morphogenetic protein-2  Gene  1997  198(1-2):341-9  PubMed ID: 9370300   DOI: 10.1016/s0378-1119(97)00336-3
3936  Nakamura T, Aikawa T, Iwamoto-Enomoto M, Iwamoto M, Higuchi Y, Pacifici M, Kinto N, Yamaguchi A, Noji S, Kurisu K, Matsuya T.  Induction of osteogenic differentiation by hedgehog proteins.  Biochem Biophys Res Commun  1997  237(2):465-9  PubMed ID: 9268735   DOI: 10.1006/bbrc.1997.7156
3808  Kinto N, Iwamoto M, Enomoto-Iwamoto M, Noji S, Ohuchi H, Yoshioka H, Kataoka H, Wada Y, Yuhao G, Takahashi HE, Yoshiki S, Yamaguchi A.  Fibroblasts expressing Sonic hedgehog induce osteoblast differentiation and ectopic bone formation.  FEBS Lett  1997  404(2-3):319-23  PubMed ID: 9119087   DOI: 10.1016/s0014-5793(97)00014-8
3937  Kobayashi T, Sugimoto T, Saijoh K, Fujii M, Chihara K.  Cloning and characterization of the 5'-flanking region of the mouse diastrophic dysplasia sulfate transporter gene.  Biochem Biophys Res Commun  1997  238(3):738-43  PubMed ID: 9325159   DOI: 10.1006/bbrc.1997.7380
15576  Katagiri T, Akiyama S, Namiki M, Komaki M, Yamaguchi A, Rosen V, Wozney JM, Fujisawa-Sehara A, Suda T.  Bone morphogenetic protein-2 inhibits terminal differentiation of myogenic cells by suppressing the transcriptional activity of MyoD and myogenin  Exp Cell Res  1997  230(2):342-51  PubMed ID: 9024793   DOI: 10.1006/excr.1996.3432
12156  Watanabe T, Takemasa T, Yonemura I, Hirabayashi T.  Regulation of troponin T gene expression in chicken fast skeletal muscle: involvement of an M-CAT-like element distinct from the standard M-CAT  J Biochem  1997  121(2):212-8  PubMed ID: 9089392  
3926  Jimi E, Nakamura I, Amano H, Taguchi Y, Tsurukai T, Tamura M, Takahashi N, Suda T.  Osteoclast function is activated by osteoblastic cells through a mechanism involving cell-to-cell contact.  Endocrinology.  1996  137(8):2187-90  PubMed ID: 8754795   DOI: 10.1210/endo.137.8.8754795
2388  Kanatani M, Sugimoto T, Kaji H, Kobayashi T, Nishiyama K, Fukase M, Kumegawa M, Chihara K.  Stimulatory effect of bone morphogenetic protein-2 on osteoclast-like cell formation and bone-resorbing activity  J Bone Miner Res  1995  10(11):1681-90  PubMed ID: 8592944   DOI: 10.1002/jbmr.5650101110
17916  Tamura M, Noda M.  Identification of a DNA sequence involved in osteoblast-specific gene expression via interaction with helix-loop-helix (HLH)-type transcription factors  J Cell Biol  1994  126(3):773-82  PubMed ID: 8045940   DOI: 10.1083/jcb.126.3.773
1329  Katagiri T, Yamaguchi A, Ikeda T, Yoshiki S, Wozney, J M, Rosen V, Wang, E A, Tanaka H, Omura S, Suda T  The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2.  Biochem Biophys Res Commun  1990  172:295-9  PubMed ID: 1699539   DOI: 10.1016/s0006-291x(05)80208-6

Back Back Return Top Page