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Cell No. : Cell Name
RCB0247 : 10T1/2  update : 2020/09/24
CommentClone 8, Contact-inhibited semi-normal
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, a prior written permission of the DEPOSITOR or the RIKEN BRC is necessary.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Terasima, Toyozo
Originator Reznikoff, Catherine A.
Year of deposit 1988
Another name 10T1/2(clone8)
Animal mouse < Mammals
Strain name C3H
Age at sampling embryo
Tissue embryo
Classification normal
Lifespan infinite
Morphology fibroblast-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives BME (2mM L-Glutamine) + 10% FBS
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage cell No 5 x 10^(4) cells/60 mm dish
SC frequency Subculture : once/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
SSLP(mouse) OK
Isozyme LD, NP
Chromosome mode 65-81(50) : /75(1),76(1),77(3),78(5),79(12),80(25)/
Images
deposit info
lot info
Reference information Reference 5
User's Publication 113


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Reference
2001  Weintraub H, Davis R, Tapscott S, Thayer M, Krause M, Benezra R, Blackwell, T K, Turner D, Rupp R, Hollenberg S, et al.  The myoD gene family: nodal point during specification of the muscle cell lineage.  Science  1991  251:761-6  PubMed ID: 1846704
962  Terasima T, Yasukawa M, Kimura M  Radiation-induced transformation of 10T 1/2 mouse cells in the plateau phase: post-irradiation changes and serum dependence.  Gann  1981  72:762-8  PubMed ID: 7327374
2000  Taylor, S M, Jones, P A  Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine.  Cell  1979  17:771-9  PubMed ID: 90553
44  Paranjpe M, del Ande Eaton S, Boone, C W  Neoplasms produced from C3H/10T 1/2 cells attached to plastic plates; saturation density, anchorage dependence and serum requirement of in vitro lines correlated with growth aggressiveness in vivo.  J Cell Physiol  1978  96:63-71  PubMed ID: 659520
961  Reznikoff, C A, Brankow, D W, Heidelberger C  Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.  Cancer Res  1973  33:3231-8  PubMed ID: 4357355

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User's Publication
12022  Sampilvanjil A, Karasawa T, Yamada N, Komada T, Higashi T, Baatarjav C, Watanabe S, Kamata R, Ohno N, Takahashi M.  Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells.  Am. J. Physiol. Heart Circ. Physiol.  2020    PubMed ID: 31975626
12066  van Gastel N, Stegen S, Eelen G, Schoors S, Carlier A, Daniëls VW, Baryawno N, Przybylski D, Depypere M, Stiers PJ, Lambrechts D, Van Looveren R, Torrekens S, Sharda A, Agostinis P, Lambrechts D, Maes F, Swinnen JV, Geris L, Van Oosterwyck H, Thienpont B, Carmeliet P, Scadden DT, Carmeliet G.  Lipid availability determines fate of skeletal progenitor cells via SOX9.  Nature  2020    PubMed ID: 32103177
11367  Ishijima Y, Ohmori S, Uneme A, Aoki Y, Kobori M, Ohida T, Arai M, Hosaka M, Ohneda K.  The Gata2 repression during 3T3-L1 preadipocyte differentiation is dependent on a rapid decrease in histone acetylation in response to glucocorticoid receptor activation.  Mol. Cell. Endocrinol.  2019    PubMed ID: 30615908
11397  Gantumur E, Sakai S, Nakahata M, Taya M.  Horseradish peroxidase-catalyzed hydrogelation consuming enzyme-produced hydrogen peroxide in the presence of reducing sugars.  Soft Matter  2019    PubMed ID: 30672948
11582  Numaga-Tomita T, Shimauchi T, Oda S, Tanaka T, Nishiyama K, Nishimura A, Birnbaumer L, Mori Y, Nishida M.  TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential-dependent coupling with PTEN.  FASEB J.  2019    PubMed ID: 31162976
11589  Aoki H, Yamashita M, Hashita T, Nakayama M, Yagi M, Iwao T, Matsunaga T.  Isolation of induced pluripotent stem cell-derived endothelial progenitor cells from sac-like structures.  Biochem. Biophys. Res. Commun.  2019  515(4):672-678  PubMed ID: 31178142
11681  Hiroe Morimoto-Ito, Masako Mizuno-Kamiya, Naoki Umemura, Yoshinori Inagaki, Eiji Takayama, Harumi Kawaki, Yasunori Muramatsu, Shinichiro Sumitomo, Nobuo Kondoh  Immunosuppressive Effect of Mesenchymal Stromal Cells is Enhanced by IL-1α from Oral Squamous Cell Carcinoma Cells  The Open Dentistry Journal  2019  13:221-227 
11738  Iriguchi S, Kaneko S.  In Vitro Differentiation of T Cells: From Nonhuman Primate-Induced Pluripotent Stem Cells.  Methods Mol. Biol.  2019    PubMed ID: 31396934
11743  Kawai Y, Kaneko S.  Redifferentiation of Adaptive Naïve-Like CTL from T-Cell-Derived iPSC.  Methods Mol. Biol.  2019    PubMed ID: 31396930
11765  Abe T, Sato T, Yoda T, Hoshi K.  The period circadian clock 2 gene responds to glucocorticoids and regulates osteogenic capacity.  Regen Ther  2019    PubMed ID: 31489343
11838  Niimi K, Adachi Y, Ishikawa H, Yamaguchi W, Kubota Y, Inagaki S, Furuyama T.  Endothelial specific deletion of FOXO1 alters pericyte coverage in the developing retina.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 31601422
6647  Takahata Y, Nakamura E, Hata K, Wakabayashi M, Murakami T, Wakamori K, Yoshikawa H, Matsuda A, Fukui N, Nishimura R.  Sox4 is involved in osteoarthritic cartilage deterioration through induction of ADAMTS4 and ADAMTS5.  FASEB J  2019  33(1):619-630  PubMed ID: 30016600
6878  Yano F, Ohba S, Murahashi Y, Tanaka S, Saito T, Chung UI.  Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation.  Sci Rep  2019  9(1):7666  PubMed ID: 31113964
6884  Iriguchi S, Kaneko S.  In Vitro Differentiation of T Cells: From Human Embryonic Stem Cells and Induced Pluripotent Stem Cells.  Methods Mol Biol  2019  2048:59-70  PubMed ID: 31396929
6907  Tagaya H, Ishikawa K, Hosokawa Y, Kobayashi S, Ueoka Y, Shimada M, Ohashi Y, Mikami H, Yamamoto M, Ihara T, Kumazawa K, Sugihara K, Goshima N, Watanabe S, Semba K.  A method of producing genetically manipulated mouse mammary gland.  Breast Cancer Res  2019  21(1):1  PubMed ID: 30611295
9893  Zhongren Hu, Shurong Hong, Yu Zhang, Huijing Dai, Shuzhen Lin, Tingyu Yi, Hongmei Zhuang  Down-regulated WDR35 Contributes to Fetal Anomaly via Regulation of Osteogenic Differentiation  Gene  2019  20;697:48-56  PubMed ID: 30790652
11014    Versatility of hydrogelation by dual-enzymatic reactions with oxidases and peroxidase  Biochemical Engineering Journal  2018  131, 1-8 
11047    Suppressive effect of mesenchymal stromal cells on interferon-γ-producing capability of spleen cells was specifically enhanced through humoral mediator(s) from mouse oral squamous cell carcinoma Sq-1979 Cells In Vitro  Cancer Translational Medicine  2018  4, 9-16 
11132  Ito Y, Nakamura S, Sugimoto N, Shigemori T, Kato Y, Ohno M, Sakuma S, Ito K, Kumon H, Hirose H, Okamoto H, Nogawa M, Iwasaki M, Kihara S, Fujio K, Matsumoto T, Higashi N, Hashimoto K, Sawaguchi A, Harimoto KI, Nakagawa M, Yamamoto T, Handa M, Watanabe N, Nishi E, Arai F, Nishimura S, Eto K.  Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production.  Cell  2018  174(3):636-648  PubMed ID: 30017246
11182  Sakai S, Mochizuki K, Qu Y, Mail M, Nakahata M, Taya M.  Peroxidase-catalyzed microextrusion bioprinting of cell-laden hydrogel constructs in vaporized ppm-level hydrogen peroxide.  Biofabrication  2018  10(4):045007  PubMed ID: 30137024
11138  Fukuda M, Yoshizawa T, Karim MF, Sobuz SU, Korogi W, Kobayasi D, Okanishi H, Tasaki M, Ono K, Sawa T, Sato Y, Chirifu M, Masuda T, Nakamura T, Tanoue H, Nakashima K, Kobashigawa Y, Morioka H, Bober E, Ohtsuki S, Yamagata Y, Ando Y, Oike Y, Araki N, Takeda S, Mizuta H, Yamagata K.  SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix.  Nat Commun  2018  9(1):2833  PubMed ID: 30026585
4059  Yoshida K, Teramachi J, Uchibe K, Ikegame M, Qiu L, Yang D, Okamura H.  Reduction of protein phosphatase 2A Cα promotes in vivo bone formation and adipocyte differentiation.  Mol. Cell. Endocrinol.  2018  470:251-258  PubMed ID: 29128580
4109  Kiyama R, Nonoyama T, Wada S, Semba S, Kitamura N, Nakajima T, Kurokawa T, Yasuda K, Tanaka S, Gong JP.  Micro patterning of hydroxyapatite by soft lithography on hydrogels for selective osteoconduction.  Acta Biomater  2018    PubMed ID: 30292679
4110  Takei H, Edahiro Y, Mano S, Masubuchi N, Mizukami Y, Imai M, Morishita S, Misawa K, Ochiai T, Tsuneda S, Endo H, Nakamura S, Eto K, Ohsaka A, Araki M, Komatsu N.  Skewed megakaryopoiesis in human induced pluripotent stem cell-derived haematopoietic progenitor cells harbouring calreticulin mutations.  Br. J. Haematol.  2018    PubMed ID: 29741776
9466  Tetsuya Kawane 1, Xin Qin, Qing Jiang, Toshihiro Miyazaki, Hisato Komori, Carolina Andrea Yoshida, Viviane Keiko Dos Santos Matsuura-Kawata, Chiharu Sakane, Yuki Matsuo, Kazuhiro Nagai, Takafumi Maeno, Yuki Date, Riko Nishimura, Toshihisa Komori   Runx2 Is Required for the Proliferation of Osteoblast Progenitors and Induces Proliferation by Regulating Fgfr2 and Fgfr3  Sci Rep  2018  10;8(1):13551  PubMed ID: 30202094
9773  Mellati A, Fan CM, Tamayol A, Annabi N, Dai S, Bi J, Jin B, Xian C, Khademhosseini A, Zhang H.  Microengineered 3D cell-laden thermoresponsive hydrogels for mimicking cell morphology and orientation in cartilage tissue engineering.  Biotechnol. Bioeng.  2017  114:217-231  PubMed ID: 27477393
10343  Khanmohammadi M, Sakai S, Taya M.  Fabrication of single and bundled filament-like tissues using biodegradable hyaluronic acid-based hollow hydrogel fibers.  Int. J. Biol. Macromol.  2017  104:204-212  PubMed ID: 28596006
11004    Migration and Osteogenic Differentiation of Mesenchymal Stem Cells on Titanium with a MicroPatterned Gelatin Matrix  International Journal of Theoretical and Applied Nanotechnology  2017  5:20-26 
6028  Kawamura F et al  Establishment of induced pluripotent stem cells from normal B cells and inducing AID expression in their differentiation into hematopoietic progenitor cells.  Sci Rep  2017  7(1):1659  PubMed ID: 28490810
10050  Ha-Eun Yang, Yongjia Li, Akira Nishimura, Huei-Fen Jheng, Ana Yuliana, Ryuji Kitano-Ohue, Wataru Nomura, Nobuyuki Takahashi, Chu-Sook Kim, Rina Yu, Nahoko Kitamura, Si-Bum Park, Shigenobu Kishino, Jun Ogawa, Teruo Kawada, Tsuyoshi Goto  Synthesized Enone Fatty Acids Resembling Metabolites From Gut Microbiota Suppress Macrophage-Mediated Inflammation in Adipocytes  Mol Nutr Food Res  2017  Oct;61(10)  PubMed ID: 28544341
9730  Mellati A, Kiamahalleh MV, Madani SH, Dai S, Bi J, Jin B, Zhang H.  Poly(N-isopropylacrylamide) hydrogel/chitosan scaffold hybrid for three-dimensional stem cell culture and cartilage tissue engineering.  J Biomed Mater Res A  2016  104:2764-74  PubMed ID: 27325374
9786  Sakai S, Nomura K, Mochizuki K, Taya M.  Anchoring PEG-oleate to cell membranes stimulates reactive oxygen species production.  Colloids Surf B Biointerfaces  2016  147:336-342  PubMed ID: 27544656
9850  Park E, Kim MC, Choi CW, Kim J, Jin HS, Lee R, Lee JW, Park JH, Huh D, Jeong SY.  Effects of Dihydrophaseic Acid 3'-O-β-d-Glucopyranoside Isolated from Lycii radicis Cortex on Osteoblast Differentiation.  Molecules  2016  21(9). pii: E1260  PubMed ID: 27657033
7113  Mellati A, Valizadeh Kiamahalleh M, Dai S, Bi J, Jin B, Zhang H.  Influence of polymer molecular weight on the in vitro cytotoxicity of poly (N-isopropylacrylamide).  Mater Sci Eng C Mater Biol Appl  2015  59:509-513  PubMed ID: 26652402
7378  Sakai S, Liu Y, Sengoku M, Taya M.  Cell-selective encapsulation in hydrogel sheaths via biospecific identification and biochemical cross-linking.  Biomaterials  2015  53:494-501  PubMed ID: 25890746
9405  Yoshikazu Mikami, Kiyofumi Yamamoto, Yuko Akiyama, Masayuki Kobayashi, Eri Watanabe, Nobukazu Watanabe, Masatake Asano, Noriyoshi Shimizu, Kazuo Komiyama  Osteogenic Gene Transcription Is Regulated via Gap Junction-Mediated Cell-Cell Communication  Stem Cells Dev  2015  24(2):214-27  PubMed ID: 25137151
10322  Ryo Nishikiori, Kotaro Watanabe, Koichi Kato  Antibody Arrays for Quality Control of Mesenchymal Stem Cells  ACS Appl Mater Interfaces  2015  7(30):16828-36  PubMed ID: 26172315
3999  Hirata N et al  A chemical probe that labels human pluripotent stem cells.  Cell Rep  2014  6(6):1165-1174  PubMed ID: 24613351
6001  Ogasawara T, Ohba S, Yano F, Kawaguchi H, Chung UI, Saito T, Yonehara Y, Nakatsuka T, Mori Y, Takato T, Hoshi K.  Nanog promotes osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2 by modulating bone morphogenetic protein (BMP) signaling.  J Cell Physiol  2013  228(1):163-71  PubMed ID: 22585661
6073  Nakagawa Y, Nakamura S, Nakajima M, Endo H, Dohda T, Takayama N, Nakauchi H, Arai F, Fukuda T, Eto K.  Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell-derived megakaryocytes.  Exp Hematol  2013  41(8):742-8  PubMed ID: 23618622
6578  Zanotti S1, Canalis E.  Notch suppresses nuclear factor of activated T cells (NFAT) transactivation and Nfatc1 expression in chondrocytes.  Endocrinology  2013  154(2):762-72  PubMed ID: 23264614
6572  Kan A, Ikeda T, Fukai A, Nakagawa T, Nakamura K, Chung UI, Kawaguchi H, Tabin CJ.  SOX11 contributes to the regulation of GDF5 in joint maintenance.  BMC Dev Biol  2013  13:4  PubMed ID: 23356643
6575  Hata K, Takashima R, Amano K, Ono K, Nakanishi M, Yoshida M, Wakabayashi M, Matsuda A, Maeda Y, Suzuki Y, Sugano S, Whitson RH, Nishimura R, Yoneda T.  Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes.  Nat Commun  2013  4:2850  PubMed ID: 24276541
5991  Takayama N, Eto K.  In vitro generation of megakaryocytes and platelets from human embryonic stem cells and induced pluripotent stem cells.  Methods Mol Biol  2012  788:205-17  PubMed ID: 22130710
6012  Zhao WH1, Hu ZQ.  Up-regulation of IL-33 expression in various types of murine cells by IL-3 and IL-4.  Cytokine  2012  58(2):267-73  PubMed ID: 22370606
5318  Gu S, Boyer TG, Naski MC.  Basic helix-loop-helix transcription factor Twist1 inhibits transactivator function of master chondrogenic regulator Sox9.  J Biol Chem.   2012  287(25):21082-92  PubMed ID: 22532563
6554  Oze H, Hirao M, Ebina K, Shi K, Kawato Y, Kaneshiro S, Yoshikawa H, Hashimoto J.  Impact of medium volume and oxygen concentration in the incubator on pericellular oxygen concentration and differentiation of murine chondrogenic cell culture.  In Vitro Cell Dev Biol Anim  2012  48(2):123-30  PubMed ID: 22259015
7632  Kawato Y, Hirao M, Ebina K, Tamai N, Shi K, Hashimoto J, Yoshikawa H, Myoui A.  Nkx3.2-induced suppression of Runx2 is a crucial mediator of hypoxia-dependent maintenance of chondrocyte phenotypes.  Biochem. Biophys. Res. Commun.  2011  416:205-10  PubMed ID: 22093831
7688  Hatakeyama Y, Hatakeyama J, Takahashi A, Oka K, Tsuruga E, Inai T, Sawa Y.  The effect of valproic Acid on mesenchymal pluripotent cell proliferation and differentiation in extracellular matrices.  Drug Target Insights  2011  5:1-9  PubMed ID: 21904447
7804  Yamagishi N, Yokota M, Yasuda K, Saito Y, Nagata K, Hatayama T.  Characterization of stress sensitivity and chaperone activity of Hsp105 in mammalian cells.  Biochem. Biophys. Res. Commun.  2011  409:90-5  PubMed ID: 21557931
7855  Shimizu T, Tanaka T, Iso T, Matsui H, Ooyama Y, Kawai-Kowase K, Arai M, Kurabayashi M.  Notch signaling pathway enhances bone morphogenetic protein 2 (BMP2) responsiveness of Msx2 gene to induce osteogenic differentiation and mineralization of vascular smooth muscle cells.  J. Biol. Chem.  2011  286:19138-48  PubMed ID: 21471203
8035  Mikami Y, Ishii Y, Watanabe N, Shirakawa T, Suzuki S, Irie S, Isokawa K, Honda MJ.  CD271/p75(NTR) inhibits the differentiation of mesenchymal stem cells into osteogenic, adipogenic, chondrogenic, and myogenic lineages.  Stem Cells Dev.  2011  20:901-13  PubMed ID: 21142793
5990  Kikuchi Y, Kume A, Urabe M, Mizukami H, Suzuki T, Ozaki K, Nagai T, Ozawa K.  Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells.  J Stem Cells Regen Med  2011  7(2):61-8  PubMed ID: 24693172
8553  Neil A Mabbott, J Kenneth Baillie, Atsushi Kobayashi, David S Donaldson, Hitoshi Ohmori, Sun-Ok Yoon, Arnold S Freedman, Tom C Freeman, Kim M Summers  Expression of Mesenchyme-Specific Gene Signatures by Follicular Dendritic Cells: Insights From the Meta-Analysis of Microarray Data From Multiple Mouse Cell Populations  Immunology   2011  133(4):482-98  PubMed ID: 21635249
8153  Takarada-Iemata M, Takarada T, Nakamura Y, Nakatani E, Hori O, Yoneda Y.  Glutamate preferentially suppresses osteoblastogenesis than adipogenesis through the cystine/glutamate antiporter in mesenchymal stem cells.  J. Cell. Physiol.  2010  226:652-65  PubMed ID: 20717926
8179  Kawai S, Abiko Y, Amano A.  Odd-skipped related 2 regulates genes related to proliferation and development.  Biochem. Biophys. Res. Commun.  2010  398:184-90  PubMed ID: 20599744
8272  Kawai S, Amano A.  Odd-skipped related 2 is epigenetically regulated in cellular quiescence.  Biochem. Biophys. Res. Commun.  2010  396:831-6  PubMed ID: 20450884
8407  Mikami Y, Asano M, Honda MJ, Takagi M.  Bone morphogenetic protein 2 and dexamethasone synergistically increase alkaline phosphatase levels through JAK/STAT signaling in C3H10T1/2 cells.  J. Cell. Physiol.  2010  223:123-33  PubMed ID: 20039267
4679  Takigawa Y, Hata K, Muramatsu S, Amano K, Ono K, Wakabayashi M, Matsuda A, Takada K, Nishimura R, Yoneda T.  The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9.  J Cell Sci  2010  123(Pt 21):3780-8  PubMed ID: 20940257
8266  Takeuchi K, Abe M, Hiasa M, Oda A, Amou H, Kido S, Harada T, Tanaka O, Miki H, Nakamura S, Nakano A, Kagawa K, Yata K, Ozaki S, Matsumoto T.  Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth.  PLoS One  2010  5(3):e9870  PubMed ID: 20360846
8562  Yuasa K, Masuda T, Yoshikawa C, Nagahama M, Matsuda Y, Tsuji A.  Subtilisin-like proprotein convertase PACE4 is required for skeletal muscle differentiation.  J. Biochem.  2009  146:407-15  PubMed ID: 19520771
8595  Osawa K, Okubo Y, Nakao K, Koyama N, Bessho K.  Osteoinduction by microbubble-enhanced transcutaneous sonoporation of human bone morphogenetic protein-2.  J Gene Med  2009  11:633-41  PubMed ID: 19396932
6131  Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H.  The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells.  Stem Cells  2009  27(5):1120-9  PubMed ID: 19415782
6534  Yanagino T, Yuasa K, Nagahama M, Matsuda Y, Tsuji A.  Transcriptional regulation of fibrillin-2 gene by E2F family members in chondrocyte differentiation.  J Cell Biochem  2009  106(4):580-8  PubMed ID: 19142862
12195  Taro Ishigaki, Kazuhiro Sudo, Takashi Hiroyama, Kenichi Miharada, Haruhiko Ninomiya, Shigeru Chiba, Toshiro Nagasawa, Yukio Nakamura  Human hematopoietic stem cells can survive in vitro for several months  Adv Hematol  2009  2009:936761  PubMed ID: 19960048
8725  Takahata Y, Takarada T, Iemata M, Yamamoto T, Nakamura Y, Kodama A, Yoneda Y.  Functional expression of beta2 adrenergic receptors responsible for protection against oxidative stress through promotion of glutathione synthesis after Nrf2 upregulation in undifferentiated mesenchymal C3H10T1/2 stem cells.  J. Cell. Physiol.  2008  218:268-75  PubMed ID: 18814142
8727  Yamauchi M, Kawai S, Kato T, Ooshima T, Amano A.  Odd-skipped related 1 gene expression is regulated by Runx2 and Ikzf1 transcription factors.  Gene  2008  426:81-90  PubMed ID: 18804520
6519  Hata K, Nishimura R, Muramatsu S, Matsuda A, Matsubara T, Amano K, Ikeda F, Harley VR, Yoneda T.  Paraspeckle protein p54nrb links Sox9-mediated transcription with RNA processing during chondrogenesis in mice.  J Clin Invest  2008  118(9):3098-108  PubMed ID: 18677406
7730  Zhao J, Ohba S, Shinkai M, Chung UI, Nagamune T.  Icariin induces osteogenic differentiation in vitro in a BMP- and Runx2-dependent manner.  Biochem Biophys Res Commun  2008  369(2):444-8  PubMed ID: 18295595
7919  Nomura-Furuwatari C, Wakitani S, Hashimoto Y, Imai Y, Ohta Y, Nakagawa K, Nakao Y, Takayama K, Manaka T, Takaoka K.  Expression profiles of phosphodiesterase 4D splicing variants in osteoblastic cells.  J Bone Miner Metab  2008  26(2):152-8  PubMed ID: 18301971
7927  Miyawaki J, Kamei S, Sakayama K, Yamamoto H, Masuno H.  4-tert-octylphenol regulates the differentiation of C3H10T1/2 cells into osteoblast and adipocyte lineages.  Toxicol Sci  2008  102(1):82-8  PubMed ID: 18065773
10904  Naoya Takayama, Hidekazu Nishikii, Joichi Usui, Hiroko Tsukui, Akira Sawaguchi, Takashi Hiroyama, Koji Eto, Hiromitsu Nakauchi  Generation of Functional Platelets From Human Embryonic Stem Cells in Vitro via ES-sacs, VEGF-promoted Structures That Concentrate Hematopoietic Progenitors  Blood  2008  111(11):5298-306  PubMed ID: 18388179
8803  Kawai S, Yamauchi M, Wakisaka S, Ooshima T, Amano A.  Zinc-finger transcription factor odd-skipped related 2 is one of the regulators in osteoblast proliferation and bone formation.  J. Bone Miner. Res.  2007  22:1362-72  PubMed ID: 17547533
3584  Muramatsu S, Wakabayashi M, Ohno T, Amano K, Ooishi R, Sugahara T, Shiojiri S, Tashiro K, Suzuki Y, Nishimura R, Kuhara S, Sugano S, Yoneda T, Matsuda A.  Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation.  J Biol Chem  2007  282(44):32158-67  PubMed ID: 17804410
7390  Iemata M, Takarada T, Hinoi E, Taniura H, Yoneda Y.  Suppression by glutamate of proliferative activity through glutathione depletion mediated by the cystine/glutamate antiporter in mesenchymal C3H10T1/2 stem cells.  J Cell Physiol  2007  213(3):721-9  PubMed ID: 17520696
3357  Hiroyama, Takashi, Miharada, Kenichi, Aoki, Naoko, Fujioka, Tsuyoshi, Sudo, Kazuhiro, Danjo, Inaho, Nagasawa, Toshiro, Nakamura, Yukio  Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells.  Exp Hematol  2006  34:760-9  PubMed ID: 16728281
6998  Kawai S, Kato T, Sato M, Amano A.  Odd-skipped related 2 gene transcription is regulated by CCAAT enhancer-binding protein delta in mesenchymal C3H10T1/2 cells.  Genes Cells  2006  11(2):163-75  PubMed ID: 16436053
3159  Miharada, Ken-ichi, Hiroyama, Takashi, Sudo, Kazuhiro, Nagasawa, Toshiro, Nakamura, Yukio  Lipocalin 2 functions as a negative regulator of red blood cell production in an autocrine fashion.  FASEB J  2005  19:1881-3  PubMed ID: 16157692
2874  Yano F, Kugimiya F, Ohba S, Ikeda T, Chikuda H, Ogasawara T, Ogata N, Takato T, Nakamura K, Kawaguchi H, Chung UI  The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.  Biochem Biophys Res Commun  2005  333:1300-8  PubMed ID: 15979579
2915  Nobta M, Tsukazaki T, Shibata Y, Xin C, Moriishi T, Sakano S, Shindo H, Yamaguchi A  Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling.  J Biol Chem  2005  280:15842-8  PubMed ID: 15695512
2936  Kawai S, Kato T, Inaba H, Okahashi N, Amano A  Odd-skipped related 2 splicing variants show opposite transcriptional activity.  Biochem Biophys Res Commun  2005  328:306-11  PubMed ID: 15670784
3183  Hata, Kenji, Nishimura, Riko, Ueda, Mio, Ikeda, Fumiyo, Matsubara, Takuma, Ichida, Fumitaka, Hisada, Kunihiro, Nokubi, Takashi, Yamaguchi, Akira, Yoneda, Toshiyuki  A CCAAT/enhancer binding protein beta isoform, liver-enriched inhibitory protein, regulates commitment of osteoblasts and adipocytes.  Mol Cell Biol  2005  25:1971-9  PubMed ID: 15713650
6876  Imai Y, Terai H, Nomura-Furuwatari C, Mizuno S, Matsumoto K, Nakamura T, Takaoka K.  Hepatocyte growth factor contributes to fracture repair by upregulating the expression of BMP receptors.  J Bone Miner Res  2005  20(10):1723-30  PubMed ID: 16160730
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