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細胞番号 : 細胞名
RCB0224 : ST2  update : 2024/08/14
細胞特性(Comment:英)Bone marrow stroma cell-derived
細胞特性(日)わが国で開発されたマウス骨髄由来のストローマ細胞で、造血幹細胞の増殖を支持できるため、フィーダーとして使用される。
細胞特性(寄託者記述:英)
細胞特性(寄託者記述:日)
使用条件(英)There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
使用条件(日)基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。
備考(英)
備考(日)
提供申込書類(英) Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 Nishikawa, Shin-ichi
樹立者 Nishikawa, Shin-ichi
寄託日 1987
動物種 _mouse < Mammals
採取組織 bone marrow
細胞分類 other
入手歴 Nishikawa(Kumamoto Univ.)
細胞寿命 infinite
細胞形態 fibroblast-like
Cellosaurus(Expasy) CVCL_2205
細胞培養・検査情報
寄託時情報
ロット情報
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 RPMI1640 + 10% FBS
抗生物質 Free
継代方法 0.25% Trypsin
継代密度 1 : 4-8 split
継代・培地交換頻度 Subculture : 1-2 times/week, Medium Renewal : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ/アコレプラズマ (-)
動物種PCR OK
染色体検査 70-80(50) : /74(5),75(5),76(6),77(11),78(12)/
画像情報
寄託時情報
ロット情報
文献情報 Reference(英) 11件
Reference(日) 2件
利用者成果(英) 346件
利用者成果(日) 2件

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Reference(英)
2436  Nishikawa S, Ogawa M, Nishikawa S, Kunisada T, Kodama H.  B lymphopoiesis on stromal cell clone: stromal cell clones acting on different stages of B cell differentiation  Eur J Immunol  1998  18(11):1767-71  PubMed ID: 3264531   DOI: 10.1002/eji.1830181117
8597  P A Welch, P D Burrows, A Namen, S Gillis, M D Cooper  Bone Marrow Stromal Cells and interleukin-7 Induce Coordinate Expression of the BP-1/6C3 Antigen and pre-B Cell Growth  Int Immunol  1990  2 (8), 697-705   PubMed ID: 2083232   DOI: 10.1093/intimm/2.8.697
2437  Hayashi S, Kunisada T, Ogawa M, Sudo T, Kodama H, Suda T, Nishikawa S, Nishikawa S.  Stepwise progression of B lineage differentiation supported by interleukin 7 and other stromal cell molecules  J Exp Med  1990  171(5):1683-95  PubMed ID: 2332734   DOI: 10.1084/jem.171.5.1683
171  Naito M, Takahashi K, Nishikawa S.  Development, differentiation, and maturation of macrophages in the fetal mouse liver  J Leukoc Biol  1990  48(1):27-37  PubMed ID: 2358750   DOI: 10.1002/jlb.48.1.27
173  Yoshida H, Hayashi S, Kunisada T, Ogawa M, Nishikawa S, Okamura H, Sudo T, Shultz LD, Nishikawa S.  The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene  Nature  1990  345(6274):442-4  PubMed ID: 2188141   DOI: 10.1038/345442a0
1987  Tominaga A, Mita S, Kikuchi Y, Hitoshi Y, Takatsu K, Nishikawa S, Ogawa M  Establishment of IL-5-dependent early B cell lines by long-term bone marrow cultures.  Growth Factors  1989  1:135-46  PubMed ID: 2624778   DOI: 10.3109/08977198909029123
2570  Sudo T, Ito M, Ogawa Y, Iizuka M, Kodama H, Kunisada T, Hayashi S, Ogawa M, Sakai K, Nishikawa S  Interleukin 7 production and function in stromal cell-dependent B cell development.  J Exp Med  1989  170:333-8  PubMed ID: 2787384   DOI: 10.1084/jem.170.1.333
172  Naito M, Yamamura F, Nishikawa S, Takahashi K.  Development, differentiation, and maturation of fetal mouse yolk sac macrophages in cultures  J Leukoc Biol  1989  46(1):1-10  PubMed ID: 2732624   DOI: 10.1002/jlb.46.1.1
174  Nishikawa S, Hayashi S, Nishikawa S, Ogawa M, Kunisada T, Sudo T, Kodama H, Suda T.  Defect of scid mouse revealed in in vitro culture systems  Curr Top Microbiol Immunol  1989  152:39-46  PubMed ID: 2805796   DOI: 10.1007/978-3-642-74974-2_6
175  Nishikawa SI, Hayashi SI, Ogawa M, Kunisada T, Nishikawa S, Sudo T, Nakauchi H, Suda T.  Control of cell growth and differentiation during early B-cell development by stromal cell molecules  Cold Spring Harb Symp Quant Biol  1989  54 Pt 1:171-4  PubMed ID: 2639751   DOI: 10.1101/sqb.1989.054.01.021
965  Ogawa M, Nishikawa S, Ikuta K, Yamamura F, Naito M, Takahashi K, Nishikawa S  B cell ontogeny in murine embryo studied by a culture system with the monolayer of a stromal cell clone, ST2: B cell progenitor develops first in the embryonal body rather than in the yolk sac.  EMBO J  1988  7:1337-43  PubMed ID: 3261687   DOI: 10.1002/j.1460-2075.1988.tb02949.x

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Reference(日)
1197  吉田尚弘,林眞一,西川伸一  骨髄幹細胞の長期培養法とその応用-大理石病マウスを具体例として-  生体防御  1990  7:145-149   
3291  西川里美  バイオテクノロジ-素材としての培養細胞 ハイブリドーマと免疫  蛋白質 核酸 酵素  1990  35:2281   

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利用者成果(英)
21637  Crawford M, Barr K, Dagnino L.  Analysis of Proliferation, Apoptosis, and Motility in Mouse Embryonic Melanocytic Precursor Cells.  Methods Mol Biol  2024    PubMed ID: 38441720   DOI: 10.1007/7651_2024_528
21648  Yamamoto M, Shibata Y, Ito Y, Fukui M, Kioka H, Shoji Y, Kitao T, Shirahase H, Hinoi E.  Osteoblastgenic and Osteogenic Effects of KY-273 with CDK8/19 Inhibitory Activity in Bone Marrow Mesenchymal Stem Cells and Female Rats.  Biol Pharm Bull  2024  47(3):669-679  PubMed ID: 38508765   DOI: 10.1248/bpb.b23-00834
21678  Takeda T, Tsubaki M, Genno S, Tomita K, Nishida S.  RANK/RANKL axis promotes migration, invasion, and metastasis of osteosarcoma via activating NF-κB pathway.  Exp Cell Res  2024  436(2):113978  PubMed ID: 38382805   DOI: 10.1016/j.yexcr.2024.113978
22001  Park EJ, Truong VL, Jeong WS, Min WK.  Brain-Derived Neurotrophic Factor (BDNF) Enhances Osteogenesis and May Improve Bone Microarchitecture in an Ovariectomized Rat Model  Cells  2024  13(6):518.  PubMed ID: 38534361   DOI: 10.3390/cells13060518
22110  Ninomiya H, Fukuda S, Nishida-Fukuda H, Shibata Y, Sato T, Nakamichi Y, Nakamura M, Udagawa N, Miyazawa K, Suzuki T.  Osteoprotegerin secretion and its inhibition by RANKL in osteoblastic cells visualized using bioluminescence imaging.  Bone  2024  117319  PubMed ID: 39500402   DOI: 10.1016/j.bone.2024.117319
17544  Shao F, Panahipour L, Gruber R.  Flavonoids from Dalbergia cochinchinensis: Impact on osteoclastogenesis  J Dent Sci  2023  18(1):112-119  PubMed ID: 36643234   DOI: 10.1016/j.jds.2022.06.026
17545  Mizukami Y, Kawao N, Takafuji Y, Ohira T, Okada K, Jo JI, Tabata Y, Kaji H.  Matrix vesicles promote bone repair after a femoral bone defect in mice  PLoS One  2023  18(4):e0284258  PubMed ID: 37027385   DOI: 10.1371/journal.pone.0284258
17750  Kitazawa S, Haraguchi R, Takaoka Y, Kitazawa R.  In situ sequence-specific visualization of single methylated cytosine on tissue sections using ICON probe and rolling-circle amplification  Histochem Cell Biol  2023  159(3):263-273  PubMed ID: 36418613   DOI: 10.1007/s00418-022-02165-2
19567  Yoshimasa Takafuji, Naoyuki Kawao, Takashi Ohira, Yuya Mizukami, Kiyotaka Okada, Jun-Ichiro Jo, Yasuhiko Tabata, Hiroshi Kaji  Extracellular vesicles secreted from mouse muscle cells improve delayed bone repair in diabetic mice  Endocrine Journal  2023  70:161-171    DOI: 10.1507/endocrj.ej22-0340
19614  Omori K, Otani S, Date Y, Ueno T, Ito T, Umeda M, Ito K.  C/ebpα represses the oncogenic Runx3-Myc axis in p53-deficient osteosarcoma development  Oncogene  2023  42(33):2485-2494  PubMed ID: 37402881   DOI: 10.1038/s41388-023-02761-z
19639  Verlinden L, Doms S, Janssens I, Meyer MB, Pike JW, Carmeliet G, Verstuyf A.  Neuropilin 2 in osteoblasts regulates trabecular bone mass in male mice  Front Endocrinol (Lausanne)  2023  14:1223021  PubMed ID: 37600714   DOI: 10.3389/fendo.2023.1223021
19734  Yamamoto M, Ito Y, Fukui M, Otake K, Shoji Y, Kitao T, Shirahase H, Hinoi E.  Osteogenic Effects of KY-054, a Novel Coumarin Derivative on Femur Cortical Bone in Ovariectomized Female Rats  Biol Pharm Bull  2023  1435-1443  PubMed ID: 37779045   DOI: 10.1248/bpb.b23-00324
19937  Seong CH, Chiba N, Fredy M, Kusuyama J, Ishihata K, Kibe T, Amir MS, Tada R, Ohnishi T, Nakamura N, Matsuguchi T.  Early induction of Hes1 by bone morphogenetic protein 9 plays a regulatory role in osteoblastic differentiation of a mesenchymal stem cell line  J Cell Biochem  2023  124(9):1366-1378  PubMed ID: 37565579   DOI: 10.1002/jcb.30452
19945  Ana Flávia Piquera Santos, Lara Cristina Cunha Cervantes, Roberta Okamoto, Antonio Carlos Guastaldi, Thallita Pereira Queiroz, Layla Panahipour, Reinhard Gruber, Francisley Ávila Souza  Interleukin-6 Expression of Osteogenic Cell Lines Grown on Laser-Treated and Hydroxyapatite-Coated Titanium Discs  Applied Sciences  2023  13:12646    DOI: 10.3390/app132312646
21006  Hatori T, Maeda T, Suzuki A, Takahashi K, Kato Y.  SPARC is a decoy counterpart for c‑Fos and is associated with osteoblastic differentiation of bone marrow stromal cells by inhibiting adipogenesis.  Mol Med Rep  2023  27(2)  PubMed ID: 36633137   DOI: 10.3892/mmr.2023.12937
21086  Kargarpour Z, Panahipour L, Mildner M, Miron RJ, Gruber R.  Lipids of Platelet-Rich Fibrin Reduce the Inflammatory Response in Mesenchymal Cells and Macrophages.  Cells  2023  12(4)  PubMed ID: 36831301   DOI: 10.3390/cells12040634
21400  Crawford M, Barr K, Dagnino L.  Isolation, Purification, and Culture of Embryonic Melanoblasts from Green Fluorescent Protein-expressing Reporter Mice.  Bio Protoc  2023  13(17):e4805  PubMed ID: 37719067   DOI: 10.21769/BioProtoc.4805
21479  Uehara N, Shibusawa N, Mikami Y, Kyumoto-Nakamura Y, Sonoda S, Kato H, Yamaza T, Kukita T.  Bone metastatic mammary tumor cell-derived extracellular vesicles inhibit osteoblast maturation via JNK signaling.  Arch Biochem Biophys  2023  750:109821  PubMed ID: 37979903   DOI: 10.1016/j.abb.2023.109821
17599  Panahipour L, Sordi MB, Kargarpour Z, Gruber R.  TGF-β Signalling Mediates the Anti-Inflammatory Activity of Enamel Matrix Derivative In Vitro  Int J Mol Sci  2022  23(17):9778  PubMed ID: 36077174   DOI: 10.3390/ijms23179778
17606  Layla Panahipour, Anes Omerbasic, Azarakhsh Oladzad Abbasabadi, Jila Nasirzade, Zahra Kargarpour, Reinhard Gruber  Anti-Inflammatory Activity of a Demineralized Bone Matrix: An In Vitro Pilot Study  Applied Sciences  2022  12:876    DOI: 10.3390/app12020876
17612  Tanaka T, Takahashi A, Kobayashi Y, Saito M, Xiaolong S, Jingquan C, Ito Y, Kato T, Ochi H, Sato S, Yoshii T, Okawa A, Carlsson P, Inose H.  Foxf2 represses bone formation via Wnt2b/β-catenin signaling  Exp Mol Med  2022  54(6):753-764  PubMed ID: 35668101   DOI: 10.1038/s12276-022-00779-z
17747  Park JW, Seo JH, Lee HJ.  Enhanced osteogenic differentiation of mesenchymal stem cells by surface lithium modification in a sandblasted/acid-etched titanium implant  J Biomater Appl  2022  37(3):447-458  PubMed ID: 35594165   DOI: 10.1177/08853282221104242
20500  Negishi T, Mihara N, Chiba T, D'Armiento J, Chada K, Maeda M, Igarashi M, Imai K.  High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development.High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development.High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development.High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development.  Biochem Biophys Res Commun  2022  590:68-74  PubMed ID: 34973532   DOI: 10.1016/j.bbrc.2021.12.093
20580  Inoue M, Nagai-Yoshioka Y, Yamasaki R, Kawamoto T, Nishihara T, Ariyoshi W.  Mechanisms involved in suppression of osteoclast supportive activity by transforming growth factor-β1 via the ubiquitin-proteasome system.  PLoS One  2022  17(2):e0262612  PubMed ID: 35196318   DOI: 10.1371/journal.pone.0262612
16338  Gámez B, Morris EV, Olechnowicz SWZ, Webb S, Edwards JR, Sowman A, Turner CJ, Edwards CM.  The antidiabetic drug metformin acts on the bone microenvironment to promote myeloma cell adhesion to preosteoblasts and increase myeloma tumour burden in vivo  Transl Oncol  2022  15(1):101301  PubMed ID: 34890968   DOI: 10.1016/j.tranon.2021.101301
16515  Sordi MB, Cabral da Cruz AC, Panahipour L, Gruber R.  Enamel Matrix Derivative Decreases Pyroptosis-Related Genes in Macrophages  Int J Mol Sci  2022  23(9):5078  PubMed ID: 35563469   DOI: 10.3390/ijms23095078
20671  Chen JR, Lazarenko OP, Blackburn ML, Chen JF, Randolph CE, Zabaleta J, Schroder K, Pedersen KB, Ronis MJJ.  Nox4 expression in osteo-progenitors controls bone development in mice during early life.  Commun Biol  2022  5(1):583  PubMed ID: 35701603   DOI: 10.1038/s42003-022-03544-0
16842  Phillips E, Ahmad N, Sun L, Iben J, Walkey CJ, Rusin A, Yuen T, Rosen CJ, Willis IM, Zaidi M, Johnson DL.  MAF1, a repressor of RNA polymerase III-dependent transcription, regulates bone mass  Elife  2022  11:e74740  PubMed ID: 35611941   DOI: 10.7554/eLife.74740
20928  Yu F, Li F, Yu P, Zhou B, Ye L.  Identification and characterization of NFATc1+ skeletal stem cells in bone regeneration.  Cell Rep  2022  41(6):111599  PubMed ID: 36351390   DOI: 10.1016/j.celrep.2022.111599
17334  Panahipour L, Abbasabadi AO, Kaiser V, Sordi MB, Kargarpour Z, Gruber R.  Damaged Mesenchymal Cells Dampen the Inflammatory Response of Macrophages and the Formation of Osteoclasts  J Clin Med  2022  11(14):4061  PubMed ID: 35887825   DOI: 10.3390/jcm11144061
21149  Panahipour L, Cervantes LCC, Oladzad Abbasabadi A, Sordi MB, Kargarpour Z, Gruber R.  Blocking of Caspases Exerts Anti-Inflammatory Effects on Periodontal Cells.  Life (Basel)  2022  12(7)  PubMed ID: 35888133   DOI: 10.3390/life12071045
13190  Parisi L, Buser D, Chappuis V, Asparuhova MB.  Cellular responses to deproteinized bovine bone mineral biofunctionalized with bone-conditioned medium.  Clin Oral Investig  2021  25(4):2159-2173  PubMed ID: 32870390   DOI: 10.1007/s00784-020-03528-6
13394  Tabuchi Y, Hasegawa H, Suzuki N, Furusawa Y, Hirano T, Nagaoka R, Hirayama J, Hoshi N, Mochizuki T.  Genetic response to low‑intensity ultrasound on mouse ST2 bone marrow stromal cells.  Mol Med Rep  2021    PubMed ID: 33398373   DOI: 10.3892/mmr.2020.11812
20134  Hariri H, Addison WN, St-Arnaud R.  Ubiquitin specific peptidase Usp53 regulates osteoblast versus adipocyte lineage commitment.  Sci Rep  2021  11(1):8418  PubMed ID: 33875709   DOI: 10.1038/s41598-021-87608-x
20179  Ito Y, Yamamoto M, Furukawa S, Fukui M, Morishita K, Kitao T, Shirahase H.  Effects of KY-903, a Novel Tetrazole-Based Peroxisome Proliferator-Activated Receptor γ Modulator, in Male Diabetic Mice and Female Ovariectomized Rats.  Biol Pharm Bull  2021  44(5):659-668  PubMed ID: 33952822   DOI: 10.1248/bpb.b20-01002
14506  Ishida M, Kawao N, Mizukami Y, Takafuji Y, Kaji H.  Influence of Angptl1 on osteoclast formation and osteoblastic phenotype in mouse cells  BMC Musculoskelet Disord  2021  22(1):398  PubMed ID: 33910546   DOI: 10.1186/s12891-021-04278-6
14509  Ishida M, Kawao N, Mizukami Y, Takafuji Y, Kaji H.  Serpinb1a suppresses osteoclast formation  Biochem Biophys Rep  2021  26:101004  PubMed ID: 33997318   DOI: 10.1016/j.bbrep.2021.101004
14783  Yu J, Choi S, Park A, Do J, Nam D, Kim Y, Noh J, Lee KY, Maeng CH, Park KS.  Bone Marrow Homeostasis Is Impaired via JAK/STAT and Glucocorticoid Signaling in Cancer Cachexia Model  Cancers (Basel)  2021  13(5):1059  PubMed ID: 33801569   DOI: 10.3390/cancers13051059
16332  Lin Z, Nica C, Sculean A, Asparuhova MB.  Positive Effects of Three-Dimensional Collagen-Based Matrices on the Behavior of Osteoprogenitors  Front Bioeng Biotechnol  2021  9:708830  PubMed ID: 34368101   DOI: 10.3389/fbioe.2021.708830
16417  Kota SK, Lim ZW, Kota SB.  Elavl1 Impacts Osteogenic Differentiation and mRNA Levels of Genes Involved in ECM Organization  Front Cell Dev Biol  2021  9:606971  PubMed ID: 33614643   DOI: 10.3389/fcell.2021.606971
16795  Kargarpour Z, Nasirzade J, Panahipour L, Miron RJ, Gruber R.  Platelet-Rich Fibrin Decreases the Inflammatory Response of Mesenchymal Cells  Int J Mol Sci  2021  22(21):11333  PubMed ID: 34768764   DOI: 10.3390/ijms222111333
17746  Nam D, Park A, Dubon MJ, Yu J, Kim W, Son Y, Park KS.  Coordinated Regulation of Mesenchymal Stem Cell Migration by Various Chemotactic Stimuli  Int J Mol Sci  2020  21(22):8561  PubMed ID: 33202862   DOI: 10.3390/ijms21228561
17748  Park JW.  Positive regulation of Porphyromonas gingivalis lipopolysaccharide-stimulated osteoblast functions by strontium modification of an SLA titanium implant surface  J Biomater Appl  2020  34(6):802-811  PubMed ID: 31558092   DOI: 10.1177/0885328219878836
18711  Yamashita-Sugahara Y, Tokuzawa Y, Nakachi Y, Kanesaki-Yatsuka Y, Matsumoto M, Mizuno Y, Okazaki Y.  Fam57b (family with sequence similarity 57, member B), a novel peroxisome proliferator-activated receptor γ target gene that regulates adipogenesis through ceramide synthesis  J Biol Chem  2020  295(15):5176  PubMed ID: 32277067   DOI: 10.1074/jbc.AAC120.013475
11638  Crawford M, Leclerc V, Barr K, Dagnino L.  Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin.  J. Invest. Dermatol.  2020  140(2):425-434  PubMed ID: 31330146   DOI: 10.1016/j.jid.2019.07.681
11881  Shiraishi N, Masumoto H, Takahashi K, Tenkumo T, Anada T, Suzuki O, Ogawa T, Sasaki K.  Histomorphometric assessments of peri-implant bone around Ti-Nb-Sn alloy implants with low Young's modulus.  Dent Mater J  2020  39(1):148-153.  PubMed ID: 31666486   DOI: 10.4012/dmj.2018-376
6952  Minamizaki T, Nakao Y, Irie Y, Ahmed F, Itoh S, Sarmin N, Yoshioka H, Nobukiyo A, Fujimoto C, Niida S, Sotomaru Y, Tanimoto K, Kozai K, Sugiyama T, Bonnelye E, Takei Y, Yoshiko Y.  The matrix vesicle cargo miR-125b accumulates in the bone matrix, inhibiting bone resorption in mice.  Commun Biol  2020  ;3(1):30  PubMed ID: 31949279   DOI: 10.1038/s42003-020-0754-2
12006  Kohara Y, Haraguchi R, Kitazawa R, Kitazawa S.  Knockdown of Lrp1 in RAW264 cells inhibits osteoclast differentiation and osteoclast-osteoblast interactions in vitro.  Biochem. Biophys. Res. Commun.  2020    PubMed ID: 31964526   DOI: 10.1016/j.bbrc.2020.01.065
12040  Tabuchi Y, Hasegawa H, Suzuki N, Furusawa Y, Hirano T, Nagaoka R, Takeuchi SI, Shiiba M, Mochizuki T.  Low-intensity pulsed ultrasound promotes the expression of immediate-early genes in mouse ST2 bone marrow stromal cells.  J Med Ultrason (2001)  2020    PubMed ID: 32026128   DOI: 10.1007/s10396-020-01007-9
12123  Kawao N, Morita H, Iemura S, Ishida M, Kaji H.  Roles of Dkk2 in the Linkage from Muscle to Bone during Mechanical Unloading in Mice.  Int J Mol Sci  2020    PubMed ID: 32268570   DOI: 10.3390/ijms21072547
12200  Tomokazu Ohnishi, Joji Kusuyama, Kenjiro Bandow, Tetsuya Matsuguchi  Glut1 expression is increased by p53 reduction to switch metabolism to glycolysis during osteoblast differentiation  Biochem J   2020  477(10):1795-1811  PubMed ID: 32242617   DOI: 10.1042/BCJ20190888
13151  Cornelis R, Hahne S, Taddeo A, Petkau G, Malko D, Durek P, Thiem M, Heiberger L, Peter L, Mohr E, Klaeden C, Tokoyoda K, Siracusa F, Hoyer BF, Hiepe F, Mashreghi MF, Melchers F, Chang HD, Radbruch A.  Stromal Cell-Contact Dependent PI3K and APRIL Induced NF-κB Signaling Prevent Mitochondrial- and ER Stress Induced Death of Memory Plasma Cells.  Cell Rep  2020    PubMed ID: 32755576   DOI: 10.1016/j.celrep.2020.107982
13197  Yahiro Y, Maeda S, Morikawa M, Koinuma D, Jokoji G, Ijuin T, Komiya S, Kageyama R, Miyazono K, Taniguchi N.  BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts.  Bone Res  2020    PubMed ID: 32923015   DOI: 10.1038/s41413-020-00106-0
13352  Ma O, Le T, Talbott G, HoangThao Nguyen T, Ha D, Ho L.  Sirt3 regulates adipogenesis and adipokine secretion via its enzymatic activity.  Pharmacol Res Perspect  2020    PubMed ID: 33191653   DOI: 10.1002/prp2.670
14181  Tsubaki M, Seki S, Takeda T, Chihara A, Arai Y, Morii Y, Imano M, Satou T, Shimomura K, Nishida S.  The HGF/Met/NF-κB Pathway Regulates RANKL Expression in Osteoblasts and Bone Marrow Stromal Cells  Int J Mol Sci  2020  21(21):7905  PubMed ID: 33114380   DOI: 10.3390/ijms21217905
14295  Takeda T, Tsubak M, Genno S, Matsuda T, Yamamoto Y, Ueda E, Imano M, Satou T, Nishida S.  CD49d and CD49e induce cell adhesion-mediated drug resistance through the nuclear factor-κB pathway in Burkitt lymphoma  J Physiol Pharmacol  2020  71(4)  PubMed ID: 33214335   DOI: 10.26402/jpp.2020.4.02
14500  Asparuhova MB, Chappuis V, Stähli A, Buser D, Sculean A.  Role of hyaluronan in regulating self-renewal and osteogenic differentiation of mesenchymal stromal cells and pre-osteoblasts  Clin Oral Investig  2020  24(11):3923-3937  PubMed ID: 32236725   DOI: 10.1007/s00784-020-03259-8
11318  Hagiwara H, Nakata K, Miyazaki H, Maehashi S, Komiyama Y, Aida R, Yoshida S, Kokubu D, Hagiwara K, Yoshida K.  4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation.  Cytotechnology  2019    PubMed ID: 30474804   DOI: 10.1007/s10616-018-0236-2
11323  Yu J, Kim HM, Kim KP, Son Y, Kim MS, Park KS.  Ceramide kinase regulates the migration of bone marrow-derived mesenchymal stem cells.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 30502084   DOI: 10.1016/j.bbrc.2018.11.154
11366  Yang X, Wang G, Wang Y, Zhou J, Yuan H, Li X, Liu Y, Wang B.  Histone demethylase KDM7A reciprocally regulates adipogenic and osteogenic differentiation via regulation of C/EBPα and canonical Wnt signalling.  J. Cell. Mol. Med.  2019    PubMed ID: 30614617   DOI: 10.1111/jcmm.14126
11439  Yu Y, Newman H, Shen L, Sharma D, Hu G, Mirando AJ, Zhang H, Knudsen E, Zhang GF, Hilton MJ, Karner CM.  Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells.  Cell Metab.  2019    PubMed ID: 30773468   DOI: 10.1016/j.cmet.2019.01.016
11460  Strauss FJ, Di Summa F, Stähli A, Matos L, Vaca F, Schuldt G, Gruber R.  TGF-β activity in acid bone lysate adsorbs to titanium surface.  Clin Implant Dent Relat Res  2019    PubMed ID: 30817088   DOI: 10.1111/cid.12734
11607  Kusuyama J, Seong C, Makarewicz NS, Ohnishi T, Shima K, Semba I, Bandow K, Matsuguchi T.  Low intensity pulsed ultrasound (LIPUS) maintains osteogenic potency by the increased expression and stability of Nanog through spleen tyrosine kinase (Syk) activation.  Cell. Signal.  2019    PubMed ID: 31228531   DOI: 10.1016/j.cellsig.2019.109345
11659  Jin‐Ran Chen, Umesh D Wankhade, Alexander W Alund, Michael L Blackburn, Kartik Shankar, Oxana P Lazarenko  3‐(3‐Hydroxyphenyl)‐Propionic Acid (PPA) Suppresses Osteoblastic Cell Senescence to Promote Bone Accretion in Mice  JBMR Plus  2019    PubMed ID: 31667457   DOI: 10.1002/jbm4.10201
11813  Böhm AM, Dirckx N, Tower RJ, Peredo N, Vanuytven S, Theunis K, Nefyodova E, Cardoen R, Lindner V, Voet T, Van Hul M, Maes C.  Activation of Skeletal Stem and Progenitor Cells for Bone Regeneration Is Driven by PDGFRβ Signaling.  Dev. Cell  2019    PubMed ID: 31543445   DOI: 10.1016/j.devcel.2019.08.013
11856  Hamaya E, Fujisawa T, Tamura M.  Osteoadherin serves roles in the regulation of apoptosis and growth in MC3T3‑E1 osteoblast cells.  Int. J. Mol. Med.  2019    PubMed ID: 31638177   DOI: 10.3892/ijmm.2019.4376
11883  Conaway HH, Henning P, Lie A, Tuckermann J, Lerner UH.  Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D3 and parathyroid hormone-induced osteoclastogenesis.  FASEB J.  2019    PubMed ID: 31675485   DOI: 10.1096/fj.201802729RRR
6927  Persson E, Souza PPC, Floriano-Marcelino T, Conaway HH, Henning P, Lerner UH.Front Immunol. 2019 May 28;10:1164. doi: 10.3389/fimmu.2019.01164. eCollection 2019.  Activation of Shc1 Allows Oncostatin M to Induce RANKL and Osteoclast Formation More Effectively Than Leukemia Inhibitory Factor.  Front Immunol  2019  2019 May 28;10:1164  PubMed ID: 31191537   DOI: 10.3389/fimmu.2019.01164
6935  SOO LENG LEE*, ZAINAL ARIFF ABDUL RAHMAN, HIDETSUGU TSUJIGIWA, MEI HAMADA, KIYOFUMI TAKABATAKE, KEISUKE NAKANO, HITOSHI NAGATSUKA & CHONG HUAT SIAR  An in vitro Three-Dimensional Co-Culture System for Ameloblastoma Modelling  Sains Malaysiana  2019  48(8):1697–1706    DOI: 10.17576/jsm-2019-4808-15
9727  Jinlu Dai, June Escara-Wilke, Jill M Keller, Younghun Jung, Russell S Taichman, Kenneth J Pienta, Evan T Keller  Primary Prostate Cancer Educates Bone Stroma Through Exosomal Pyruvate Kinase M2 to Promote Bone Metastasis  J Exp Med  2019  216(12):2883-2899  PubMed ID: 31548301   DOI: 10.1084/jem.20190158
10553  Naru Shiraishi, Risa Ishiko-Uzuka, Kenta Takahashi, Toru Ogawa, Takahisa Anada, Osamu Suzuki, Takashi Goto and Keiichi Sasaki  Effect of Functionally-Graded Calcium Titanate Film, Prepared by Metal-Organic Chemical Vapor Deposition, on Titanium Implant  Appl Sci  2019  9(1):172    DOI: 10.3390/app9010172
12590  Mashimo K, Tsubaki M, Takeda T, Asano R, Jinushi M, Imano M, Satou T, Sakaguchi K, Nishida S.  RANKL-induced c-Src activation contributes to conventional anti-cancer drug resistance and dasatinib overcomes this resistance in RANK-expressing multiple myeloma cells  Clin Exp Med  2019  19(1):133-141  PubMed ID: 30291461   DOI: 10.1007/s10238-018-0531-4
12591  Sone E, Noshiro D, Ikebuchi Y, Nakagawa M, Khan M, Tamura Y, Ikeda M, Oki M, Murali R, Fujimori T, Yoda T, Honma M, Suzuki H, Ando T, Aoki K.  The induction of RANKL molecule clustering could stimulate early osteoblast differentiation  Biochem Biophys Res Commun  2019  509(2):435-440  PubMed ID: 30594398   DOI: 10.1016/j.bbrc.2018.12.093
12592  Takeno A, Kanazawa I, Tanaka KI, Notsu M, Sugimoto T.  Phloretin Suppresses Bone Morphogenetic Protein-2-Induced Osteoblastogenesis and Mineralization via Inhibition of Phosphatidylinositol 3-kinases/Akt Pathway  Int J Mol Sci  2019  20(10):2481  PubMed ID: 31137461   DOI: 10.3390/ijms20102481
10459  Kusuyama J, Kamisono A, ChangHwan S, Amir MS, Bandow K, Eiraku N, Ohnishi T, Matsuguchi T.  Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities.  J. Cell. Physiol.  2018  233:2549-2559  PubMed ID: 28786489   DOI: 10.1002/jcp.26130
10666  Takeno A, Kanazawa I, Notsu M, Tanaka KI, Sugimoto T.  Inhibition of adenosine monophosphate-activated protein kinase suppresses bone morphogenetic protein-2-induced mineralization of osteoblasts via Smad-independent mechanisms.  Endocr. J.  2018  65:291-298  PubMed ID: 29249772   DOI: 10.1507/endocrj.EJ17-0229
10731  Kumeta M, Takahashi D, Takeyasu K, Yoshimura SH.  Cell type-specific suppression of mechanosensitive genes by audible sound stimulation.  PLoS ONE  2018  13:e0188764  PubMed ID: 29385174   DOI: 10.1371/journal.pone.0188764
10764  Takeda T, Tsubaki M, Tomonari Y, Kawashima K, Itoh T, Imano M, Satou T, Nishida S.  Bavachin induces the apoptosis of multiple myeloma cell lines by inhibiting the activation of nuclear factor kappa B and signal transducer and activator of transcription 3.  Biomed. Pharmacother.  2018  100:486-494  PubMed ID: 29477912   DOI: 10.1016/j.biopha.2018.02.019
10844  Takenaka Y, Mikami K, Seno S, Matsuda H.  Automated transition analysis of activated gene regulation during diauxic nutrient shift in Escherichia coli and adipocyte differentiation in mouse cells.  BMC Bioinformatics  2018  19:89  PubMed ID: 29745848   DOI: 10.1186/s12859-018-2072-y
11198  Ikebuchi Y, Aoki S, Honma M, Hayashi M, Sugamori Y, Khan M, Kariya Y, Kato G, Tabata Y, Penninger JM, Udagawa N, Aoki K, Suzuki H.  Coupling of bone resorption and formation by RANKL reverse signalling.  Nature  2018  561(7722):195-200  PubMed ID: 30185903   DOI: 10.1038/s41586-018-0482-7
11099  Asparuhova MB, Caballe-Serrano J, Buser D, Chappuis V.  Bone-conditioned medium contributes to initiation and progression of osteogenesis by exhibiting synergistic TGF-β1/BMP-2 activity.  Int J Oral Sci  2018  10(2):20  PubMed ID: 29895828   DOI: 10.1038/s41368-018-0021-2
11124  Kida J, Hata K, Nakamura E, Yagi H, Takahata Y, Murakami T, Maeda Y, Nishimura R.  Interaction of LEF1 with TAZ is necessary for the osteoblastogenic activity of Wnt3a.  Sci Rep  2018  8(1):10375  PubMed ID: 29991769   DOI: 10.1038/s41598-018-28711-4
11153  Kuroda M, Ueda K, Kioka N.  Vinexin family (SORBS) proteins regulate mechanotransduction in mesenchymal stem cells.  Sci Rep  2018  8(1):11581  PubMed ID: 30068914   DOI: 10.1038/s41598-018-29700-3
11193  Eppell SJ, Tong W, McMasters J, Soenjaya Y, Barbu AM, Ko A, Baskin JZ.  Minor Review: An Overview of a Synthetic Nanophase Bone Substitute.  Materials (Basel)  2018  11(9)  PubMed ID: 30158464   DOI: 10.3390/ma11091556
4348  Kokubun K, Matsumura S, Yudasaka M, Iijima S, Shiba K.  Immobilization of a carbon nanomaterial-based localized drug-release system using a bispecific material-binding peptide.  Int J Nanomedicine  2018    PubMed ID: 29588591   DOI: 10.2147/IJN.S155913
4349  Takeno A, Kanazawa I, Notsu M, Tanaka KI, Sugimoto T.  Phloretin Promotes Adipogenesis via Mitogen-Activated Protein Kinase Pathways in Mouse Marrow Stromal ST2 Cells.  Int J Mol Sci  2018    PubMed ID: 29904032   DOI: 10.3390/ijms19061772
4350  Aoto K, Ito K, Aoki S.  Complex formation between platelet-derived growth factor receptor β and transforming growth factor β receptor regulates the differentiation of mesenchymal stem cells into cancer-associated fibroblasts.  Oncotarget  2018    PubMed ID: 30344924   DOI: 10.18632/oncotarget.26124
4351  Dubon MJ, Yu J, Choi S, Park KS.  Transforming growth factor β induces bone marrow mesenchymal stem cell migration via noncanonical signals and N-cadherin.  J. Cell. Physiol.  2018    PubMed ID: 28213973   DOI: 10.1002/jcp.25863
4502  Choi SM, Park JW.  Multifunctional effects of a modification of SLA titanium implant surface with strontium-containing nanostructures on immunoinflammatory and osteogenic cell function.  J Biomed Mater Res A  2018  106(12):3009-3020  PubMed ID: 30192064   DOI: 10.1002/jbm.a.36490
14552  Kota SK, Roening C, Patel N, Kota SB, Baron R.  PRMT5 inhibition promotes osteogenic differentiation of mesenchymal stromal cells and represses basal interferon stimulated gene expression  Bone  2018  117:37-46  PubMed ID: 30189247   DOI: 10.1016/j.bone.2018.08.025
14900  Fujioka-Kobayashi M, Abd El Raouf M, Saulacic N, Kobayashi E, Zhang Y, Schaller B, Miron RJ.  Superior bone-inducing potential of rhBMP9 compared to rhBMP2  J Biomed Mater Res A  2018  106(6):1561-1574.  PubMed ID: 29396910   DOI: 10.1002/jbm.a.36359
9589  Miron RJ, Fujioka-Kobayashi M, Zhang Y, Caballé-Serrano J, Shirakata Y, Bosshardt DD, Buser D, Sculean A.  Osteogain improves osteoblast adhesion, proliferation and differentiation on a bovine-derived natural bone mineral.  Clin Oral Implants Res  2017  28:327-333  PubMed ID: 26919609   DOI: 10.1111/clr.12802
9860  Fujioka-Kobayashi M, Schaller B, Saulacic N, Zhang Y, Miron RJ.  Growth factor delivery of BMP9 using a novel natural bovine bone graft with integrated atelo-collagen type I: Biosynthesis, characterization, and cell behavior.  J Biomed Mater Res A  2017  105:408-418  PubMed ID: 27699987   DOI: 10.1002/jbm.a.35921
9874  Fujioka-Kobayashi M, Mottini M, Kobayashi E, Zhang Y, Schaller B, Miron RJ.  An in vitro study of fibrin sealant as a carrier system for recombinant human bone morphogenetic protein (rhBMP)-9 for bone tissue engineering.  J Craniomaxillofac Surg  2017  45:27-32  PubMed ID: 27840120   DOI: 10.1016/j.jcms.2016.10.008
9878  Fujioka-Kobayashi M, Schaller B, Zhang Y, Kandalam U, Hernandez M, Miron RJ.  Recombinant human bone morphogenetic protein (rhBMP)9 induces osteoblast differentiation when combined with demineralized freeze-dried bone allografts (DFDBAs) or biphasic calcium phosphate (BCP).  Clin Oral Investig  2017  21:1883-1893  PubMed ID: 27771827   DOI: 10.1007/s00784-016-1983-0
9967  Miron RJ, Fujioka-Kobayashi M, Zhang Y, Sculean A, Pippenger B, Shirakata Y, Kandalam U, Hernandez M.  Osteogain® loaded onto an absorbable collagen sponge induces attachment and osteoblast differentiation of ST2 cells in vitro.  Clin Oral Investig  2017  21:2265-2272  PubMed ID: 27909893   DOI: 10.1007/s00784-016-2019-5
9975  Sato M, Suzuki T, Kawano M, Tamura M.  Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells.  Biomed Rep  2017  6:223-231  PubMed ID: 28357077   DOI: 10.3892/br.2016.824
10067  Zhang M, Osisami M, Dai J, Keller JM, Escara-Wilke J, Mizokami A, Keller ET.  Bone Microenvironment Changes in Latexin Expression Promote Chemoresistance.  Mol. Cancer Res.  2017  15:457-466  PubMed ID: 28087740   DOI: 10.1158/1541-7786.MCR-16-0392
10074  Takano A, Fukuda T, Shinjo T, Iwashita M, Matsuzaki E, Yamamichi K, Takeshita M, Sanui T, Nishimura F.  Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation.  Metab. Clin. Exp.  2017  69:157-170  PubMed ID: 28285646   DOI: 10.1016/j.metabol.2017.01.006
10090  Kuroda M, Wada H, Kimura Y, Ueda K, Kioka N.  Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes.  J. Cell. Sci.  2017  130:989-1002  PubMed ID: 28115535   DOI: 10.1242/jcs.194779
10104  Chaweewannakorn W, Ariyoshi W, Okinaga T, Morikawa K, Saeki K, Maki K, Nishihara T.  Ameloblastin and enamelin prevent osteoclast formation by suppressing RANKL expression via MAPK signaling pathway.  Biochem. Biophys. Res. Commun.  2017  485:621-626  PubMed ID: 28161637   DOI: 10.1016/j.bbrc.2017.01.181
10125  Fujioka-Kobayashi M, Schaller B, Saulacic N, Pippenger BE, Zhang Y, Miron RJ.  Absorbable collagen sponges loaded with recombinant bone morphogenetic protein 9 induces greater osteoblast differentiation when compared to bone morphogenetic protein 2.  Clin Exp Dent Res  2017  3:32-40  PubMed ID: 29744176   DOI: 10.1002/cre2.55
10316  Aikawa T, Matsubara H, Ugaji S, Shirakawa J, Nagai R, Munesue S, Harashima A, Yamamoto Y, Tsuchiya H.  Contribution of methylglyoxal to delayed healing of bone injury in diabetes.  Mol Med Rep  2017  16:403-409  PubMed ID: 28534951   DOI: 10.3892/mmr.2017.6589
10395  Takada H, Ibaragi S, Eguchi T, Okui T, Obata K, Masui M, Morisawa A, Takabatake K, Kawai H, Yoshioka N, Hassan NMM, Shimo T, Hu GF, Nagatsuka H, Sasaki A.  Semaphorin 4D promotes bone invasion in head and neck squamous cell carcinoma.  Int. J. Oncol.  2017  51:625-632  PubMed ID: 28656278   DOI: 10.3892/ijo.2017.4050
10401  Ouji Y, Sakagami M, Omori H, Higashiyama S, Kawai N, Kitahara T, Wanaka A, Yoshikawa M.  Efficient induction of inner ear hair cell-like cells from mouse ES cells using combination of Math1 transfection and conditioned medium from ST2 stromal cells.  Stem Cell Res  2017  23:50-56  PubMed ID: 28689068   DOI: 10.1016/j.scr.2017.06.013
10647  Ono-Ohmachi A, Ishida Y, Morita Y, Kato K, Y Nara T.  Milk Basic Protein Facilitates Increased Bone Mass in Growing Mice.  J. Nutr. Sci. Vitaminol.  2017  63:315-322  PubMed ID: 29225316   DOI: 10.3177/jnsv.63.315
14009  Chen JR, Lazarenko OP, Blackburn ML, Shankar K.  Dietary factors during early life program bone formation in female rats  FASEB J  2017  31(1):376-387  PubMed ID: 27733448   DOI: 10.1096/fj.201600703R
14377  Fujioka-Kobayashi M, Sawada K, Kobayashi E, Schaller B, Zhang Y, Miron RJ.  Osteogenic potential of rhBMP9 combined with a bovine-derived natural bone mineral scaffold compared to rhBMP2  Clin Oral Implants Res  2017  28(4):381-387  PubMed ID: 26988608   DOI: 10.1111/clr.12804
14442  Fujioka-Kobayashi M, Schaler B, Shirakata Y, Nakamura T, Noguchi K, Zhang Y, Miron RJ.  Comparison of Two Porcine Collagen Membranes Combined with rhBMP-2 and rhBMP-9 on Osteoblast Behavior In Vitro  Int J Oral Maxillofac Implants  2017  32(4):e221-e230  PubMed ID: 28708926   DOI: 10.11607/jomi.5652
14448  Miron RJ, Fujioka-Kobayashi M, Buser D, Zhang Y, Bosshardt DD, Sculean A.  Combination of Collagen Barrier Membrane with Enamel Matrix Derivative-Liquid Improves Osteoblast Adhesion and Differentiation  Int J Oral Maxillofac Implants   2017  32(1):196-203  PubMed ID: 28095524   DOI: 10.11607/jomi.5011
14712  Fujioka-Kobayashi M, Schaller B, Zhang Y, Pippenger BE, Miron RJ.  In vitro evaluation of an injectable biphasic calcium phosphate (BCP) carrier system combined with recombinant human bone morphogenetic protein (rhBMP)-9  Biomed Mater Eng  2017  28(3):293-304  PubMed ID: 28527192   DOI: 10.3233/BME-171675
7186  Park JW, Kang DG, Hanawa T.  New bone formation induced by surface strontium-modified ceramic bone graft substitute.  Oral Dis  2016  22:53-61  PubMed ID: 26458092   DOI: 10.1111/odi.12381
9531  Tsubaki M, Takeda T, Yoshizumi M, Ueda E, Itoh T, Imano M, Satou T, Nishida S.  RANK-RANKL interactions are involved in cell adhesion-mediated drug resistance in multiple myeloma cell lines.  Tumour Biol.  2016  37:9099-110  PubMed ID: 26762414   DOI: 10.1007/s13277-015-4761-8
9558  Pal SK, Nguyen CT, Morita KI, Miki Y, Kayamori K, Yamaguchi A, Sakamoto K.  THBS1 is induced by TGFB1 in the cancer stroma and promotes invasion of oral squamous cell carcinoma.  J. Oral Pathol. Med.  2016  45:730-739  PubMed ID: 26850833   DOI: 10.1111/jop.12430
9575  Dubon MJ, Park KS.  The mechanisms of substance P-mediated migration of bone marrow-derived mesenchymal stem cell-like ST2 cells.  Int. J. Mol. Med.  2016  37:1105-11  PubMed ID: 26936322   DOI: 10.3892/ijmm.2016.2496
9639  Yoshikawa M, Ouji Y.  Induction of Inner Ear Hair Cells from Mouse Embryonic Stem Cells In Vitro.  Methods Mol. Biol.  2016  1516:257-267  PubMed ID: 27032944   DOI: 10.1007/7651_2016_328
9752  Ye X, Huang H, Zhao N, Zhang J, Yang P.  Inhibition of Runx2 signaling by TNF-α in ST2 murine bone marrow stromal cells undergoing osteogenic differentiation.  In Vitro Cell. Dev. Biol. Anim.  2016  52:1026-1033  PubMed ID: 27401008   DOI: 10.1007/s11626-016-0068-3
9785  Kusuyama J, Komorizono A, Bandow K, Ohnishi T, Matsuguchi T.  CXCL3 positively regulates adipogenic differentiation.  J. Lipid Res.  2016  57:1806-1820  PubMed ID: 27512010   DOI: 10.1194/jlr.M067207
9882  Moriwaki S, Into T, Suzuki K, Miyauchi M, Takata T, Shibayama K, Niida S.  γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.  Sci Rep  2016  6:35930  PubMed ID: 27775020   DOI: 10.1038/srep35930
9961  Onishi T, Tazawa H, Hashimoto Y, Takeuchi M, Otani T, Nakamura S, Sakurai F, Mizuguchi H, Kishimoto H, Umeda Y, Shirakawa Y, Urata Y, Kagawa S, Fujiwara T.  Tumor-specific delivery of biologics by a novel T-cell line HOZOT.  Sci Rep  2016  6:38060  PubMed ID: 27901098   DOI: 10.1038/srep38060
9966  Fujioka-Kobayashi M, Schaller B, Kobayashi E, Hernandez M, Zhang Y, Miron RJ.  Hyaluronic Acid Gel-Based Scaffolds as Potential Carrier for Growth Factors: An In Vitro Bioassay on Its Osteogenic Potential.  J Clin Med  2016  5:  PubMed ID: 27916889   DOI: 10.3390/jcm5120112
10871  Du M, Pan W, Duan X, Yang P, Ge S.  Lower dosage of aspirin promotes cell growth and osteogenic differentiation in murine bone marrow stromal cells  J Dent Sci  2016  11:315-322  PubMed ID: 30894990   DOI: 10.1016/j.jds.2016.03.009
10902    Effects of gallotannin on osteoclastogenesis and the p38 MAP kinase pathway  Orthodontic Waves  2016  75, 105-113    DOI: 10.1016/j.odw.2016.10.007
10864  Fujioka-Kobayashi M, Sawada K, Kobayashi E, Schaller B, Zhang Y, Miron RJ.  Recombinant Human Bone Morphogenetic Protein 9 (rhBMP9) Induced Osteoblastic Behavior on a Collagen Membrane Compared With rhBMP2  J Periodontol  2016  87(6):e101-7  PubMed ID: 26751345   DOI: 10.1902/jop.2016.150561
14079  Sugamori Y, Mise-Omata S, Maeda C, Aoki S, Tabata Y, Murali R, Yasuda H, Udagawa N, Suzuki H, Honma M, Aoki K.  Peptide drugs accelerate BMP-2-induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling  Bioessays  2016  38(8):717-25  PubMed ID: 27345003   DOI: 10.1002/bies.201600104
14084  Sarker B, Li W, Zheng K, Detsch R, Boccaccini AR.  Designing Porous Bone Tissue Engineering Scaffolds with Enhanced Mechanical Properties from Composite Hydrogels Composed of Modified Alginate, Gelatin, and Bioactive Glass  ACS Biomater Sci Eng  2016  2(12):2240-2254  PubMed ID: 33465897   DOI: 10.1021/acsbiomaterials.6b00470
7111  Endo K, Anada T, Yamada M, Seki M, Sasaki K, Suzuki O.  Enhancement of osteoblastic differentiation in alginate gel beads with bioactive octacalcium phosphate particles.  Biomed Mater  2015  10:065019  PubMed ID: 26657659   DOI: 10.1088/1748-6041/10/6/065019
7265  Kanda N, Anada T, Handa T, Kobayashi K, Ezoe Y, Takahashi T, Suzuki O.  Orthotopic Osteogenecity Enhanced by a Porous Gelatin Sponge in a Critical-Sized Rat Calvaria Defect.  Macromol Biosci  2015  15:1647-55  PubMed ID: 26200698   DOI: 10.1002/mabi.201500191
7338  Kaneshiro S, Otsuki D, Yoshida K, Yoshikawa H, Higuchi C.  MEK5 suppresses osteoblastic differentiation.  Biochem. Biophys. Res. Commun.  2015  463:241-7  PubMed ID: 25998381   DOI: 10.1016/j.bbrc.2015.05.035
7434  Dubon MJ, Park KS.  Substance P enhances the proliferation and migration potential of murine bone marrow-derived mesenchymal stem cell-like cell lines.  Exp Ther Med  2015  9:1185-1191  PubMed ID: 25780407   DOI: 10.3892/etm.2015.2291
7440  Takahashi K, Shiraishi N, Ishiko-Uzuka R, Anada T, Suzuki O, Masumoto H, Sasaki K.  Biomechanical evaluation of Ti-Nb-Sn alloy implants with a low Young's modulus.  Int J Mol Sci  2015  16:5779-88  PubMed ID: 25775158   DOI: 10.3390/ijms16035779
7509  Kaneko K, Higuchi C, Kunugiza Y, Yoshida K, Sakai T, Yoshikawa H, Nakata K.  Hyaluronan inhibits BMP-induced osteoblast differentiation.  FEBS Lett.  2015  589:447-54  PubMed ID: 25592835   DOI: 10.1016/j.febslet.2014.12.031
7511  Li C, Shi C, Kim J, Chen Y, Ni S, Jiang L, Zheng C, Li D, Hou J, Taichman RS, Sun H.  Erythropoietin promotes bone formation through EphrinB2/EphB4 signaling.  J. Dent. Res.  2015  94:455-63  PubMed ID: 25586589   DOI: 10.1177/0022034514566431
7570  Y Ezoe, T Anada, H Yamazaki, T Handa, K Kobayashi, T Takahashi, O. Suzuki  Characterization of partially hydrolyzed OCP crystals deposited in a gelatin matrix as a scaffold for bone tissue engineering.  J Nanoparticle Res.  2015  17:127    DOI: 10.1007/s11051-015-2864-1
8888  Abe-Ohya R, Ishikawa T, Shiozawa H, Suda K, Nara F.  Identification of metals from osteoblastic ST-2 cell supernatants as novel OGR1 agonists.  J Recept Signal Transduct Res  2015  35(5):485-92  PubMed ID: 26053506   DOI: 10.3109/10799893.2015.1015736
6619  Peng J, Nemec M, Brolese E, Bosshardt DD, Schaller B, Buser D, Gruber R  Bone-Conditioned Medium Inhibits Osteogenic and Adipogenic Differentiation of Mesenchymal Cells In Vitro.  Clin Implant Dent Relat Res  2015  17(5):938-49  PubMed ID: 24461197   DOI: 10.1111/cid.12200
9369  Hirom iHagiwara, Roshan Basnet, Sundari I.Wiyasihati, Kyoko Nakata, Keitaro Hagiwara, Hitoshi Miyazaki, Kaoru Yoshida  Carnosic acid inhibits the formation of osteoclasts through attenuation of expression of RANKL  PharmaNutrition  2015  3:1-6    DOI: 10.1016/j.phanu.2014.11.003
9397  Shoichi Kaneshiro, Kosuke Ebina, Kenrin Shi, Kiyoshi Yoshida, Dai Otsuki, Hideki Yoshikawa, Chikahisa Higuchi  Bruton Tyrosine Kinase (Btk) Suppresses Osteoblastic Differentiation  J Bone Miner Metab  2015  33(5):486-95  PubMed ID: 25230818   DOI: 10.1007/s00774-014-0612-8
12236  K Sawada, J Caballé-Serrano, G Schuldt Filho, D D Bosshardt, B Schaller, D Buser 6, R Gruber  Thermal processing of bone: in vitro response of mesenchymal cells to bone-conditioned medium  Int J Oral Maxillofac Surg  2015  44(8):1060-6  PubMed ID: 25868709   DOI: 10.1016/j.ijom.2015.03.012
14310  Filho GS, Caballé-Serrano J, Sawada K, Bosshardt DD, Bianchini MA, Buser D, Gruber R.  Conditioned medium of demineralized freeze-dried bone activates gene expression in periodontal fibroblasts in vitro  J Periodontol  2015  86(6):827-34  PubMed ID: 25786563   DOI: 10.1902/jop.2015.140676
13891  Nakamura R, Kayamori K, Oue E, Sakamoto K, Harada K, Yamaguchi A.  Transforming growth factor-β synthesized by stromal cells and cancer cells participates in bone resorption induced by oral squamous cell carcinoma  Biochem Biophys Res Commun  2015  458(4):777-82  PubMed ID: 25681764   DOI: 10.1016/j.bbrc.2015.02.013
6031  Hattori H, Ishihara M.  Altered protein secretions during interactions between adipose tissue- or bone marrow-derived stromal cells and inflammatory cells  Stem Cell Res Ther   2015  6(1):70  PubMed ID: 25884474   DOI: 10.1186/s13287-015-0052-y
5203  Nallamshetty S, Le PT, Wang H, Issacsohn MJ, Reeder DJ, Rhee EJ, Kiefer FW, Brown JD, Rosen CJ, Plutzky J  Retinaldehyde dehydrogenase 1 deficiency inhibits PPARγ-mediated bone loss and marrow adiposity.  Bone  2014  281-91  PubMed ID: 25064526   DOI: 10.1016/j.bone.2014.07.005
2777  Yamasaki T, Ariyoshi W, Okinaga T, Adachi Y, Hosokawa R, Mochizuki S, Sakurai K, Nishihara T.  The dectin 1 agonist curdlan regulates osteoclastogenesis by inhibiting nuclear factor of activated T cells cytoplasmic 1 (NFATc1) through Syk kinase.  J Biol Chem  2014  289(27):19191-203  PubMed ID: 24821724   DOI: 10.1074/jbc.M114.551416
6592  Swarnkar G, Zhang K, Mbalaviele G, Long F, Abu-Amer Y.  Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development.  PLoS One  2014  9(3):e91421  PubMed ID: 24618907   DOI: 10.1371/journal.pone.0091421
6604  Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, Nagano S, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S.  Human immunodeficiency virus type 1 enhancer-binding protein 3 is essential for the expression of asparagine-linked glycosylation 2 in the regulation of osteoblast and chondrocyte differentiation.  J Biol Chem  2014  89(14):9865-79  PubMed ID: 24563464   DOI: 10.1074/jbc.M113.520585
6610  Nishikawa R, Anada T, Ishiko-Uzuka R, Suzuki O.  Osteoblastic differentiation of stromal ST-2 cells from octacalcium phosphate exposure via p38 signaling pathway.  Dent Mater J  2014  33(2):242-51  PubMed ID: 24598239   DOI: 10.4012/dmj.2013-226
9332  Joji Kusuyama, Kenjiro Bandow, Mitsuo Shamoto, Kyoko Kakimoto, Tomokazu Ohnishi, Tetsuya Matsuguchi  Low Intensity Pulsed Ultrasound (LIPUS) Influences the Multilineage Differentiation of Mesenchymal Stem and Progenitor Cell Lines Through ROCK-Cot/Tpl2-MEK-ERK Signaling Pathway  J Biol Chem  2014  289(15):10330-44  PubMed ID: 24550383   DOI: 10.1074/jbc.M113.546382
9336  Ken-ichiro Tanaka, Hiroshi Kaji, Toru Yamaguchi, Ippei Kanazawa, Lucie Canaff, Geoffrey N Hendy, Toshitsugu Sugimoto  Involvement of the Osteoinductive Factors, Tmem119 and BMP-2, and the ER Stress Response PERK-eIF2α-ATF4 Pathway in the Commitment of Myoblastic Into Osteoblastic Cells  Calcif Tissue Int  2014  94(4):454-64  PubMed ID: 24362451   DOI: 10.1007/s00223-013-9828-1
9345  Sunao Takeshita, Toshio Fumoto, Yoshinori Naoe, Kyoji Ikeda  Age-related Marrow Adipogenesis Is Linked to Increased Expression of RANKL  J Biol Chem  2014  289(24):16699-710  PubMed ID: 24753250   DOI: 10.1074/jbc.M114.547919
9347  Jinlu Dai, Honglai Zhang, Andreas Karatsinides, Jill M Keller, Kenneth M Kozloff, Dana T Aftab, Frauke Schimmoller, Evan T Keller  Cabozantinib Inhibits Prostate Cancer Growth and Prevents Tumor-Induced Bone Lesions  Clin Cancer Res  2014  20(3):617-30  PubMed ID: 24097861   DOI: 10.1158/1078-0432.CCR-13-0839
9348  W Ariyoshi, T Okinaga, C B Knudson, W Knudson, T Nishihara  High Molecular Weight Hyaluronic Acid Regulates Osteoclast Formation by Inhibiting Receptor Activator of NF-κB Ligand Through Rho Kinase  Osteoarthritis Cartilage  2014  22(1):111-20  PubMed ID: 24185105   DOI: 10.1016/j.joca.2013.10.013
9350  Masakazu Notsu, Toru Yamaguchi, Kyoko Okazaki, Ken-ichiro Tanaka, Noriko Ogawa, Ippei Kanazawa, Toshitsugu Sugimoto  Advanced Glycation End Product 3 (AGE3) Suppresses the Mineralization of Mouse Stromal ST2 Cells and Human Mesenchymal Stem Cells by Increasing TGF-β Expression and Secretion  Endocrinology  2014  155(7):2402-10  PubMed ID: 24758301   DOI: 10.1210/en.2013-1818
9352  Kiyoshi Mori, Riko Kitazawa, Takeshi Kondo, Michiko Mori, Yasuhiro Hamada, Michiru Nishida, Yasuhiro Minami, Ryuma Haraguchi, Yutaka Takahashi, Sohei Kitazawa  Diabetic Osteopenia by Decreased β-Catenin Signaling Is Partly Induced by Epigenetic Derepression of sFRP-4 Gene  PLoS One  2014  9(7):e102797  PubMed ID: 25036934   DOI: 10.1371/journal.pone.0102797
9271  Masato Tamura, Maki Uyama, Yuri Sugiyama, Mari Sato  Canonical Wnt Signaling Activates miR-34 Expression During Osteoblastic Differentiation  Mol Med Rep  2013  8(6):1807-11  PubMed ID: 24100761   DOI: 10.3892/mmr.2013.1713
9278  Shingen Nakamura, Hirokazu Miki, Shinsuke Kido, Ayako Nakano, Masahiro Hiasa, Asuka Oda, Hiroe Amou, Keiichiro Watanabe, Takeshi Harada, Shiro Fujii, Kyoko Takeuchi, Kumiko Kagawa, Shuji Ozaki, Toshio Matsumoto, Masahiro Abe  Activating Transcription Factor 4, an ER Stress Mediator, Is Required For, but Excessive ER Stress Suppresses Osteoblastogenesis by Bortezomib  Int J Hematol  2013  98(1):66-73  PubMed ID: 23708974   DOI: 10.1007/s12185-013-1367-z
9289  Yuan Jiang, Jinlu Dai, Honglai Zhang, Joe L Sottnik, Jill M Keller, Katherine J Escott, Hitesh J Sanganee, Zhi Yao, Laurie K McCauley, Evan T Keller  Activation of the Wnt Pathway Through AR79, a GSK3β Inhibitor, Promotes Prostate Cancer Growth in Soft Tissue and Bone  Mol Cancer Res  2013  11(12):1597-610  PubMed ID: 24088787   DOI: 10.1158/1541-7786.MCR-13-0332-T
9292  James J Cody, Angel A Rivera, Gray R Lyons, Sherry W Yang, Minghui Wang, Jason W Ashley, Sreelatha Meleth, Xu Feng, Gene P Siegal, Joanne T Douglas  Expression of Osteoprotegerin From a Replicating Adenovirus Inhibits the Progression of Prostate Cancer Bone Metastases in a Murine Model  Lab Invest  2013  93(3):268-78  PubMed ID: 23358109   DOI: 10.1038/labinvest.2012.179
10992  Yasuhiro Takenaka, Ikuo Inoue, Takanari Nakano, Yuichi Shinoda, Masaaki Ikeda, Takuya Awata, Shigehiro Katayama  A Novel Splicing Variant of Peroxisome Proliferator-Activated Receptor-γ (Pparγ1sv) Cooperatively Regulates Adipocyte Differentiation with Pparγ2  PLoS One  2013  8(6):e65583  PubMed ID: 23840343   DOI: 10.1371/journal.pone.0065583
12708  Kim Y, Kelly OJ, Ilich JZ.  Synergism of α-linolenic acid, conjugated linoleic acid and calcium in decreasing adipocyte and increasing osteoblast cell growth  Lipids  2013  48(8):787-802  PubMed ID: 23757205   DOI: 10.1007/s11745-013-3803-5
7600  Handa T, Anada T, Honda Y, Yamazaki H, Kobayashi K, Kanda N, Kamakura S, Echigo S, Suzuki O.  The effect of an octacalcium phosphate co-precipitated gelatin composite on the repair of critical-sized rat calvarial defects.  Acta Biomater  2012  8:1190-200  PubMed ID: 22198138   DOI: 10.1016/j.actbio.2011.12.002
7673  Honami T, Shimo T, Okui T, Kurio N, Hassan NM, Iwamoto M, Sasaki A.  Sonic hedgehog signaling promotes growth of oral squamous cell carcinoma cells associated with bone destruction.  Oral Oncol.  2012  48:49-55  PubMed ID: 21945071   DOI: 10.1016/j.oraloncology.2011.08.026
6097  Oue E, Lee JW, Sakamoto K, Iimura T, Aoki K, Kayamori K, Michi Y, Yamashiro M, Harada K, Amagasa T, Yamaguchi A.  CXCL2 synthesized by oral squamous cell carcinoma is involved in cancer-associated bone destruction.  Biochem Biophys Res Commun  2012  424(3):456-61  PubMed ID: 22771802   DOI: 10.1016/j.bbrc.2012.06.132
6102  Tsubaki M, Satou T, Itoh T, Imano M, Yanae M, Kato C, Takagoshi R, Komai M, Nishida S.  Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2.  Mol Cell Endocrinol  2012  361(1-2):219-31  PubMed ID: 22579611   DOI: 10.1016/j.mce.2012.05.002
9248  Y Ouji, S Ishizaka, F Nakamura-Uchiyama, M Yoshikawa  In Vitro Differentiation of Mouse Embryonic Stem Cells Into Inner Ear Hair Cell-Like Cells Using Stromal Cell Conditioned Medium  Cell Death Dis  2012  3(5):e314  PubMed ID: 22622133   DOI: 10.1038/cddis.2012.56
9251  Shoichiro Kokabu, Laura Gamer, Karen Cox, Jonathan Lowery, Kunikazu Tsuji, Regina Raz, Aris Economides, Takenobu Katagiri, Vicki Rosen  BMP3 Suppresses Osteoblast Differentiation of Bone Marrow Stromal Cells via Interaction With Acvr2b  Mol Endocrinol  2012  26(1):87-94  PubMed ID: 22074949   DOI: 10.1210/me.2011-1168
7674  Huang H, Zhao N, Xu X, Xu Y, Li S, Zhang J, Yang P.  Dose-specific effects of tumor necrosis factor alpha on osteogenic differentiation of mesenchymal stem cells.  Cell Prolif.  2011  44:420-7  PubMed ID: 21951285   DOI: 10.1111/j.1365-2184.2011.00769.x
7744  Yoshida K, Higuchi C, Nakura A, Yoshikawa H.  Spleen tyrosine kinase suppresses osteoblastic differentiation through MAPK and PKCα.  Biochem. Biophys. Res. Commun.  2011  411:774-9  PubMed ID: 21782794   DOI: 10.1016/j.bbrc.2011.07.023
7774  Furugaki K, Moriya Y, Iwai T, Yorozu K, Yanagisawa M, Kondoh K, Fujimoto-Ohuchi K, Mori K.  Erlotinib inhibits osteolytic bone invasion of human non-small-cell lung cancer cell line NCI-H292.  Clin. Exp. Metastasis  2011  28:649-59  PubMed ID: 21688034   DOI: 10.1007/s10585-011-9398-4
7829  Shoji K, Tsubaki M, Yamazoe Y, Satou T, Itoh T, Kidera Y, Tanimori Y, Yanae M, Matsuda H, Taga A, Nakamura H, Nishida S.  Mangiferin induces apoptosis by suppressing Bcl-xL and XIAP expressions and nuclear entry of NF-κB in HL-60 cells.  Arch. Pharm. Res.  2011  34:469-75  PubMed ID: 21547680   DOI: 10.1007/s12272-011-0316-8
7921  Kurio N, Shimo T, Fukazawa T, Takaoka M, Okui T, Hassan NM, Honami T, Hatakeyama S, Ikeda M, Naomoto Y, Sasaki A.  Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo.  Exp. Cell Res.  2011  317:1134-46  PubMed ID: 21338601   DOI: 10.1016/j.yexcr.2011.02.008
7943  Hu R, Liu W, Li H, Yang L, Chen C, Xia ZY, Guo LJ, Xie H, Zhou HD, Wu XP, Luo XH.  A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation.  J. Biol. Chem.  2011  286:12328-39  PubMed ID: 21324897   DOI: 10.1074/jbc.M110.176099
7955  Tamura M, Sato MM, Nashimoto M.  Regulation of CXCL12 expression by canonical Wnt signaling in bone marrow stromal cells.  Int. J. Biochem. Cell Biol.  2011  43:760-7  PubMed ID: 21296678   DOI: 10.1016/j.biocel.2011.01.021
8004  Taipaleenmaki H, Abdallah BM, AlDahmash A, Saamanen AM, Kassem M.  Wnt signalling mediates the cross-talk between bone marrow derived pre-adipocytic and pre-osteoblastic cell populations.  Exp. Cell Res.  2011  317:745-56  PubMed ID: 21211534   DOI: 10.1016/j.yexcr.2010.12.015
8069  Tsuneto M, Yamane T, Hayashi S.  Methods for investigation of osteoclastogenesis using mouse embryonic stem cells.  Methods Mol. Biol.  2011  690:239-53  PubMed ID: 21042997   DOI: 10.1007/978-1-60761-962-8_16
8575  Yoshiaki Kariya, Masashi Honma, Akiko Hanamura, Shigeki Aoki, Tadashi Ninomiya, Yuko Nakamichi, Nobuyuki Udagawa, Hiroshi Suzuki  Rab27a and Rab27b Are Involved in Stimulation-Dependent RANKL Release From Secretory Lysosomes in Osteoblastic Cells  J Bone Miner Res  2011  26(4):689-703   PubMed ID: 20939018   DOI: 10.1002/jbmr.268
8102  Lee JW, Mase N, Yonezawa T, Seo HJ, Jeon WB, Cha BY, Nagai K, Woo JT.  Palmatine attenuates osteoclast differentiation and function through inhibition of receptor activator of nuclear factor-κb ligand expression in osteoblast cells.  Biol. Pharm. Bull.  2010  33:1733-9  PubMed ID: 20930384   DOI: 10.1248/bpb.33.1733
8113  Okui T, Shimo T, Fukazawa T, Kurio N, Hassan NM, Honami T, Takaoka M, Naomoto Y, Sasaki A.  Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction.  Mol. Cancer Ther.  2010  9:2960-9  PubMed ID: 20858724   DOI: 10.1158/1535-7163.MCT-10-0489
8139  Cody JJ, Rivera AA, Lyons GR, Yang SW, Wang M, Sarver DB, Wang D, Selander KS, Kuo HC, Meleth S, Feng X, Siegal GP, Douglas JT.  Arming a replicating adenovirus with osteoprotegerin reduces the tumor burden in a murine model of osteolytic bone metastases of breast cancer.  Cancer Gene Ther.  2010  17:893-905  PubMed ID: 20798695   DOI: 10.1038/cgt.2010.47
8182  Uemura T, Ohta Y, Nakao Y, Manaka T, Nakamura H, Takaoka K.  Epinephrine accelerates osteoblastic differentiation by enhancing bone morphogenetic protein signaling through a cAMP/protein kinase A signaling pathway.  Bone  2010  47:756-65  PubMed ID: 20637325   DOI: 10.1016/j.bone.2010.07.008
8220  Kakegawa A, Oida S, Gomi K, Nagano T, Yamakoshi Y, Fukui T, Kanazashi M, Arai T, Fukae M.  Cytodifferentiation activity of synthetic human enamel sheath protein peptides.  J. Periodont. Res.  2010  45:643-9  PubMed ID: 20572923   DOI: 10.1111/j.1600-0765.2010.01279.x
19100  Matsui A, Anada T, Masuda T, Honda Y, Miyatake N, Kawai T, Kamakura S, Echigo S, Suzuki O.  Mechanical stress-related calvaria bone augmentation by onlayed octacalcium phosphate-collagen implant  Tissue Eng Part A  2010  16(1):139-51  PubMed ID: 19642866   DOI: 10.1089/ten.TEA.2009.0284
19261  Ha H, Lee HY, Lee JH, Jung D, Choi J, Song KY, Jung HJ, Choi JS, Chang SI, Kim C.  Formononetin prevents ovariectomy-induced bone loss in rats  Arch Pharm Res  2010  33(4):625-32  PubMed ID: 20422373   DOI: 10.1007/s12272-010-0418-8
8295  Tokuzawa Y, Yagi K, Yamashita Y, Nakachi Y, Nikaido I, Bono H, Ninomiya Y, Kanesaki-Yatsuka Y, Akita M, Motegi H, Wakana S, Noda T, Sablitzky F, Arai S, Kurokawa R, Fukuda T, Katagiri T, Schönbach C, Suda T, Mizuno Y, Okazaki Y.  Id4, a new candidate gene for senile osteoporosis, acts as a molecular switch promoting osteoblast differentiation.  PLoS Genet  2010  6(7):e1001019  PubMed ID: 20628571   DOI: 10.1371/journal.pgen.1001019
16149  Kayamori K, Sakamoto K, Nakashima T, Takayanagi H, Morita K, Omura K, Nguyen ST, Miki Y, Iimura T, Himeno A, Akashi T, Yamada-Okabe H, Ogata E, Yamaguchi A.  Roles of interleukin-6 and parathyroid hormone-related peptide in osteoclast formation associated with oral cancers: significance of interleukin-6 synthesized by stromal cells in response to cancer cells  Am J Pathol  2010  176(2):968-80  PubMed ID: 20035059   DOI: 10.2353/ajpath.2010.090299
8359  Lee JW, Ahn JY, Hasegawa S, Cha BY, Yonezawa T, Nagai K, Seo HJ, Jeon WB, Woo JT.  Inhibitory effect of luteolin on osteoclast differentiation and function.  Cytotechnology  2009  61:125-34  PubMed ID: 20162352   DOI: 10.1007/s10616-010-9253-5
8493  Kurtova AV, Balakrishnan K, Chen R, Ding W, Schnabl S, Quiroga MP, Sivina M, Wierda WG, Estrov Z, Keating MJ, Shehata M, Jager U, Gandhi V, Kay NE, Plunkett W, Burger JA.  Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance.  Blood  2009  114:4441-50  PubMed ID: 19762485   DOI: 10.1182/blood-2009-07-233718
8530  Yoshikawa H, Yoshioka K, Nakase T, Itoh K.  Stimulation of ectopic bone formation in response to BMP-2 by Rho kinase inhibitor: a pilot study.  Clin. Orthop. Relat. Res.  2009  467:3087-95  PubMed ID: 19609629   DOI: 10.1007/s11999-009-0976-6
8570  Fuji T, Anada T, Honda Y, Shiwaku Y, Koike H, Kamakura S, Sasaki K, Suzuki O.  Octacalcium phosphate-precipitated alginate scaffold for bone regeneration.  Tissue Eng Part A  2009  15:3525-35  PubMed ID: 19456237   DOI: 10.1089/ten.TEA.2009.0048
8584  Tanaka T, Kawashima H, Ohnishi K, Matsumura K, Yoshimura R, Matsuyama M, Kuratsukuri K, Nakatani T.  Indirect antitumor effects of bisphosphonates on prostatic LNCaP cells co-cultured with bone cells.  Anticancer Res.  2009  29:1089-94  PubMed ID: 19414350  
8594  Mogi M, Kondo A.  Down-regulation of mTOR leads to up-regulation of osteoprotegerin in bone marrow cells.  Biochem. Biophys. Res. Commun.  2009  384:82-6  PubMed ID: 19393224   DOI: 10.1016/j.bbrc.2009.04.084
8652  Yano K, Hoshino M, Ohta Y, Manaka T, Naka Y, Imai Y, Sebald W, Takaoka K.  Osteoinductive capacity and heat stability of recombinant human bone morphogenetic protein-2 produced by Escherichia coli and dimerized by biochemical processing.  J. Bone Miner. Metab.  2009  27:355-63  PubMed ID: 19229473   DOI: 10.1007/s00774-009-0040-3
8669  Honda Y, Anada T, Kamakura S, Morimoto S, Kuriyagawa T, Suzuki O.  The effect of microstructure of octacalcium phosphate on the bone regenerative property.  Tissue Eng Part A  2009  15:1965-73  PubMed ID: 19132890   DOI: 10.1089/ten.tea.2008.0300
8766  Yamachika E, Tsujigiwa H, Shirasu N, Ueno T, Sakata Y, Fukunaga J, Mizukawa N, Yamada M, Sugahara T.  Immobilized recombinant human bone morphogenetic protein-2 enhances the phosphorylation of receptor-activated Smads.  J Biomed Mater Res A  2009  88:599-607  PubMed ID: 18314893   DOI: 10.1002/jbm.a.31833
6536  Kanamoto T, Mizuhashi K, Terada K, Minami T, Yoshikawa H, Furukawa T.  Isolation and characterization of a novel plasma membrane protein, osteoblast induction factor (obif), associated with osteoblast differentiation.  BMC Dev Biol  2009  9:70  PubMed ID: 20025746   DOI: 10.1186/1471-213X-9-70
8180  Kim CH, Kim KH, Jacobs CR.  Effects of high frequency loading on RANKL and OPG mRNA expression in ST-2 murine stromal cells.  BMC Musculoskelet Disord  2009  10:109  PubMed ID: 19728893   DOI: 10.1186/1471-2474-10-109
8183  Nose M, Yamazaki H, Hagino H, Morio Y, Hayashi S, Teshima R.  Comparison of osteoclast precursors in peripheral blood mononuclear cells from rheumatoid arthritis and osteoporosis patients.  J Bone Miner Metab  2009  27(1):57-65  PubMed ID: 19082778   DOI: 10.1007/s00774-008-0011-0
6530  Anada T, Kumagai T, Honda Y, Masuda T, Kamijo R, Kamakura S, Yoshihara N, Kuriyagawa T, Shimauchi H, Suzuki O.  Dose-dependent osteogenic effect of octacalcium phosphate on mouse bone marrow stromal cells.  Tissue Eng Part A  2008  14(6):965-78  PubMed ID: 19230123   DOI: 10.1089/ten.tea.2007.0339
7863  Maehira F1, Iinuma Y, Eguchi Y, Miyagi I, Teruya S.  Effects of soluble silicon compound and deep-sea water on biochemical and mechanical properties of bone and the related gene expression in mice.  J Bone Miner Metab  2008  26(5):446-55  PubMed ID: 18758902   DOI: 10.1007/s00774-007-0845-x
7919  Nomura-Furuwatari C, Wakitani S, Hashimoto Y, Imai Y, Ohta Y, Nakagawa K, Nakao Y, Takayama K, Manaka T, Takaoka K.  Expression profiles of phosphodiesterase 4D splicing variants in osteoblastic cells.  J Bone Miner Metab  2008  26(2):152-8  PubMed ID: 18301971   DOI: 10.1007/s00774-007-0803-7
7920  Hagiwara H, Sugizaki T, Tsukamoto Y, Senoh E, Goto T, Ishihara Y.  Effects of alkylphenols on bone metabolism in vivo and in vitro.  Toxicol Lett  2008  181(1):13-8  PubMed ID: 18621119   DOI: 10.1016/j.toxlet.2008.06.863
7930  You L, Temiyasathit S, Lee P, Kim CH, Tummala P, Yao W, Kingery W, Malone AM, Kwon RY, Jacobs CR.  Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading.  Bone  2008  42(1):172-9  PubMed ID: 17997378   DOI: 10.1016/j.bone.2007.09.047
18620  Notoya M, Arai R, Katafuchi T, Minamino N, Hagiwara H.  A novel member of the calcitonin gene-related peptide family, calcitonin receptor-stimulating peptide, inhibits the formation and activity of osteoclasts  Eur J Pharmacol  2007  560(2-3):234-9  PubMed ID: 17328890   DOI: 10.1016/j.ejphar.2007.01.034
7073  Tsubaki M, Kato C, Manno M, Ogaki M, Satou T, Itoh T, Kusunoki T, Tanimori Y, Fujiwara K, Matsuoka H, Nishida S.  Macrophage inflammatory protein-1alpha (MIP-1alpha) enhances a receptor activator of nuclear factor kappaB ligand (RANKL) expression in mouse bone marrow stromal cells and osteoblasts through MAPK and PI3K/Akt pathways.  Mol Cell Biochem  2007  304(1-2):53-60  PubMed ID: 17549607   DOI: 10.1007/s11010-007-9485-7
7354  Takahashi N, Udagawa N, Kobayashi Y, Suda T.  Generation of osteoclasts in vitro, and assay of osteoclast activity.  Methods Mol Med  2007  135:285-301  PubMed ID: 17951666   DOI: 10.1007/978-1-59745-401-8_18
7383  Pregizer S, Barski A, Gersbach CA, García AJ, Frenkel B.  Identification of novel Runx2 targets in osteoblasts: cell type-specific BMP-dependent regulation of Tram2.  J Cell Biochem  2007  102(6):1458-71  PubMed ID: 17486635   DOI: 10.1002/jcb.21366
7386  Amano S, Arai M, Goto S, Togari A.  Inhibitory effect of NPY on isoprenaline-induced osteoclastogenesis in mouse bone marrow cells.  Biochim Biophys Acta  2007  1770(6):966-73  PubMed ID: 17383824   DOI: 10.1016/j.bbagen.2007.02.009
7391  Horiuchi K, Miyamoto T, Takaishi H, Hakozaki A, Kosaki N, Miyauchi Y, Furukawa M, Takito J, Kaneko H, Matsuzaki K, Morioka H, Blobel CP, Toyama Y.  Cell surface colony-stimulating factor 1 can be cleaved by TNF-alpha converting enzyme or endocytosed in a clathrin-dependent manner.  J Immunol  2007  179(10):6715-24  PubMed ID: 17982061   DOI: 10.4049/jimmunol.179.10.6715
7392  Niikura K, Nakajima S, Takano M, Yamazaki H.  FR177995, a novel vacuolar ATPase inhibitor, exerts not only an inhibitory effect on bone destruction but also anti-immunoinflammatory effects in adjuvant-induced arthritic rats.  Bone  2007  40(4):888-94  PubMed ID: 17157574   DOI: 10.1016/j.bone.2006.10.015
13955  Nakagawa K, Imai Y, Ohta Y, Takaoka K.  Prostaglandin E2 EP4 agonist (ONO-4819) accelerates BMP-induced osteoblastic differentiation  Bone  2007  41(4):543-8  PubMed ID: 17681894   DOI: 10.1016/j.bone.2007.06.013
8891  Tsujigiwa H, Nagatsuka H, Lee YJ, Han PP, Gunduz M, Legeros RZ, Inoue M, Yamada M, Nagai N.  Immobilized rhBMP-2/succinylated type I atelocollagen gene expression of intracellular signaling molecules on ST2 cells.  J Biomed Mater Res A  2006  77:507-11  PubMed ID: 16482552   DOI: 10.1002/jbm.a.30661
8913  Hidetsugu Tsujigiwa, Andrea P. Rodriguez, Tohru Takagi, Hu Hai Long, Kan Rui, Zhenfu Lu, Xie Wei Li, Gao Wen-Xin, Jin Tan and Jing Xiao  Effects of Immobilized rhBMP-2/atelocollagen in vivo and in vitro  J Hard Tissue Biology  2006  15:27-33    DOI: 10.2485/jhtb.15.27
18628  Kim CH, You L, Yellowley CE, Jacobs CR.  Oscillatory fluid flow-induced shear stress decreases osteoclastogenesis through RANKL and OPG signaling  Bone  2006  39(5):1043-1047  PubMed ID: 16860618   DOI: 10.1016/j.bone.2006.05.017
6151  Nagayoshi K, Ohkawa H, Yorozu K, Higuchi M, Higashi S, Kubota N, Fukui H, Imai N, Gojo S, Hata J, Kobayashi Y, Umezawa A.  Increased mobilization of c-kit+ Sca-1+ Lin- (KSL) cells and colony-forming units in spleen (CFU-S) following de novo formation of a stem cell niche depends on dynamic, but not stable, membranous ossification.  J Cell Physiol  2006  208(1):188-94  PubMed ID: 16575918   DOI: 10.1002/jcp.20652
6493  Shinoda Y, Yamaguchi M, Ogata N, Akune T, Kubota N, Yamauchi T, Terauchi Y, Kadowaki T, Takeuchi Y, Fukumoto S, Ikeda T, Hoshi K, Chung UI, Nakamura K, Kawaguchi H.  Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways.  J Cell Biochem  2006  99(1):196-208  PubMed ID: 16598753   DOI: 10.1002/jcb.20890
6997  Sugama R, Koike T, Imai Y, Nomura-Furuwatari C, Takaoka K.  Bone morphogenetic protein activities are enhanced by 3',5'-cyclic adenosine monophosphate through suppression of Smad6 expression in osteoprogenitor cells.  Bone  2006  38(2):206-14  PubMed ID: 16203197   DOI: 10.1016/j.bone.2005.08.006
7012  Shirakawa K, Maeda S, Gotoh T, Hayashi M, Shinomiya K, Ehata S, Nishimura R, Mori M, Onozaki K, Hayashi H, Uematsu S, Akira S, Ogata E, Miyazono K, Imamura T.  CCAAT/enhancer-binding protein homologous protein (CHOP) regulates osteoblast differentiation.  Mol Cell Biol  2006  26(16):6105-16  PubMed ID: 16880521   DOI: 10.1128/MCB.02429-05
7024  Shin HH, Kim SJ, Kang SY, Lee DS, Choi HS.  Soluble glucocorticoid-induced tumor necrosis factor receptor stimulates osteoclastogenesis by down-regulation of osteoprotegerin in bone marrow stromal cells.  Bone  2006  39(4):716-23  PubMed ID: 16750437   DOI: 10.1016/j.bone.2006.03.015
12830  Ohno T, Okahashi N, Kawai S, Kato T, Inaba H, Shibata Y, Morisaki I, Abiko Y, Amano A.  Proinflammatory gene expression in mouse ST2 cell line in response to infection by Porphyromonas gingivalis  Microbes Infect   2006  8(4):1025-34  PubMed ID: 16476562   DOI: 10.1016/j.micinf.2005.10.021
13953  Nagano T, Oida S, Suzuki S, Iwata T, Yamakoshi Y, Ogata Y, Gomi K, Arai T, Fukae M.  Porcine enamel protein fractions contain transforming growth factor-beta1  J Periodontol  2006  77(10):1688-94  PubMed ID: 17032111   DOI: 10.1902/jop.2006.050352
13957  Suzuki O, Kamakura S, Katagiri T, Nakamura M, Zhao B, Honda Y, Kamijo R.  Bone formation enhanced by implanted octacalcium phosphate involving conversion into Ca-deficient hydroxyapatite  Biomaterials  2006  27(13):2671-81  PubMed ID: 16413054   DOI: 10.1016/j.biomaterials.2005.12.004
2300  Rossa C, Ehmann K, Liu M, Patil C, Kirkwood KL.  MKK3/6-p38 MAPK signaling is required for IL-1beta and TNF-alpha-induced RANKL expression in bone marrow stromal cells  J Interferon Cytokine Res  2006  26(10):719-29  PubMed ID: 17032166   DOI: 10.1089/jir.2006.26.719
3294  Deshimaru, Ryota, Ishitani, Ken, Makita, Kazuya, Horiguchi, Fumi, Nozawa, Shiro  Analysis of fatty acid composition in human bone marrow aspirates.  Keio J Med  2005  54:150-5  PubMed ID: 16237277   DOI: 10.2302/kjm.54.150
2879  Nishida S, Tsubaki M, Hoshino M, Namimatsu A, Uji H, Yoshioka S, Tanimori Y, Yanae M, Iwaki M, Irimajiri K  Nitrogen-containing bisphosphonate, YM529/ONO-5920 (a novel minodronic acid), inhibits RANKL expression in a cultured bone marrow stromal cell line ST2.  Biochem Biophys Res Commun  2005  328:91-7  PubMed ID: 15670755   DOI: 10.1016/j.bbrc.2004.12.145
3366  Oursler, Merry Jo, Bradley, Elizabeth W, Elfering, Sarah L, Giulivi, Cecilia  Native, not nitrated, cytochrome c and mitochondria-derived hydrogen peroxide drive osteoclast apoptosis.  Am J Physiol Cell Physiol  2005  288:C156-68  PubMed ID: 15342339   DOI: 10.1152/ajpcell.00092.2004
3183  Hata, Kenji, Nishimura, Riko, Ueda, Mio, Ikeda, Fumiyo, Matsubara, Takuma, Ichida, Fumitaka, Hisada, Kunihiro, Nokubi, Takashi, Yamaguchi, Akira, Yoneda, Toshiyuki  A CCAAT/enhancer binding protein beta isoform, liver-enriched inhibitory protein, regulates commitment of osteoblasts and adipocytes.  Mol Cell Biol  2005  25:1971-9  PubMed ID: 15713650   DOI: 10.1128/MCB.25.5.1971-1979.2005
2843  Takeuchi, Tamotsu, Adachi, Yoshihiro, Ohtsuki, Yuji  Skeletrophin, a novel ubiquitin ligase to the intracellular region of Jagged-2, is aberrantly expressed in multiple myeloma.  Am J Pathol  2005  166:1817-26  PubMed ID: 15920166   DOI: 10.1016/S0002-9440(10)62491-1
3377  Hall, Christopher L, Bafico, Anna, Dai, Jinlu, Aaronson, Stuart A, Keller, Evan T  Prostate cancer cells promote osteoblastic bone metastases through Wnts.  Cancer Res  2005  65:7554-60  PubMed ID: 16140917   DOI: 10.1158/0008-5472.CAN-05-1317
8993  Tsujigiwa H, Nagatsuka H, Gunduz M, Rodriguez A, Rivera RS, Legeros RZ, Inoue M, Nagai N.  Effects of immobilized recombinant human bone morphogenetic protein-2/succinylated type I atelocollagen on cellular activity of ST2 cells.  J Biomed Mater Res A  2005  75:210-5  PubMed ID: 16059889   DOI: 10.1002/jbm.a.30416
9055  Kandler B, Maitz P, Fischer MB, Watzek G, Gruber R.  Platelets can neutralize hydrogen peroxide in an acute toxicity model with cells involved in granulation tissue formation.  Bone  2005  36:671-7  PubMed ID: 15784190   DOI: 10.1016/j.bone.2005.01.015
6866  O. Suzuki et al  Effects of mechanical stress and scaffold material on osteogenesis and chondrogenesis  IEEE Xplore  2005      DOI: 10.1109/MHS.2005.1589996
6870  Robins JC, Akeno N, Mukherjee A, Dalal RR, Aronow BJ, Koopman P, Clemens TL.  Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9.  Bone  2005  37(3):313-22  PubMed ID: 16023419   DOI: 10.1016/j.bone.2005.04.040
6877  Liu J, Yang H, Liu W, Cao X, Feng X.  Sp1 and Sp3 regulate the basal transcription of receptor activator of nuclear factor kappa B ligand gene in osteoblasts and bone marrow stromal cells.  J Cell Biochem  2005  96(4):716-27  PubMed ID: 16052479   DOI: 10.1002/jcb.20569
2871  Notoya M, Otsuka E, Yamaguchi A, Hagiwara H  Runx-2 is not essential for the vitamin D-regulated expression of RANKL and osteoprotegerin in osteoblastic cells.  Biochem Biophys Res Commun  2004  324:655-60  PubMed ID: 15474477   DOI: 10.1016/j.bbrc.2004.09.101
2910  Fan, Xian, Roy, Eileen, Zhu, Liping, Murphy, Tamara C, Ackert-Bicknell, Cheryl, Hart, C Michael, Rosen, Clifford, Nanes, Mark S, Rubin, Janet  Nitric oxide regulates receptor activator of nuclear factor-kappaB ligand and osteoprotegerin expression in bone marrow stromal cells.  Endocrinology  2004  145:751-9  PubMed ID: 14563699   DOI: 10.1210/en.2003-0726
2926  French, Dorothy M, Kaul, Raji J, D'Souza, Aloma L, Crowley, Craig W, Bao, Min, Frantz, Gretchen D, Filvaroff, Ellen H, Desnoyers, Luc  WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair.  Am J Pathol  2004  165:855-67  PubMed ID: 15331410   DOI: 10.1016/S0002-9440(10)63348-2
6737  Naruse M, Otsuka E, Naruse M, Ishihara Y, Miyagawa-Tomita S, Hagiwara H.  Inhibition of osteoclast formation by 3-methylcholanthrene, a ligand for arylhydrocarbon receptor: suppression of osteoclast differentiation factor in osteogenic cells.  Biochem Pharmacol  2004  67(1):119-27  PubMed ID: 14667934   DOI: 10.1016/j.bcp.2003.08.038
6739  Karst M, Gorny G, Galvin RJ, Oursler MJ.  Roles of stromal cell RANKL, OPG, and M-CSF expression in biphasic TGF-beta regulation of osteoclast differentiation.  J Cell Physiol  2004  200(1):99-106  PubMed ID: 15137062   DOI: 10.1002/jcp.20036
15606  Gorny G, Shaw A, Oursler MJ.  IL-6, LIF, and TNF-alpha regulation of GM-CSF inhibition of osteoclastogenesis in vitro  Exp Cell Res  2004  294(1):149-58  PubMed ID: 14980510   DOI: 10.1016/j.yexcr.2003.11.009
16483    Osteopontin as a positive regulator in the osteoclastogenesis of arthritis  Biochem Biophys Res Commun  2004  316(3):809-15  PubMed ID: 15033472   DOI: 10.1016/j.bbrc.2004.02.124
3059  Tazoe, Michiko, Mogi, Makio, Goto, Shigemi, Togari, Akifumi  Involvement of p38MAP kinase in bone morphogenetic protein-4-induced osteoprotegerin in mouse bone-marrow-derived stromal cells.  Arch Oral Biol  2003  48:615-9  PubMed ID: 12828991   DOI: 10.1016/s0003-9969(03)00100-6
5407  Yamagami H, Nishioka T, Ochiai E, Fukushima K, Nomura M, Kasugai S, Moritani S, Yokogawa K, Miyamoto K.  Inhibition of osteoclastogenesis by a phosphodiesterase 4 inhibitor XT-611 through synergistic action with endogenous prostaglandin E2.  Biochem Pharmacol  2003  66(5):801-7  PubMed ID: 12948861   DOI: 10.1016/s0006-2952(03)00409-x
4964  Gruber R, Graninger W, Bobacz K, Watzek G, Erlacher L.  BMP-6-induced osteogenic differentiation of mesenchymal cell lines is not modulated by sex steroids and resveratrol.  Cytokine  2003  23(4-5):133-7  PubMed ID: 12967649   DOI: 10.1016/s1043-4666(03)00223-0
4415  Itoh F, Aoyagi S, Furihata-Komatsu H, Aoki M, Kusama H, Kojima M, Kogo H.  Clodronate stimulates osteoblast differentiation in ST2 and MC3T3-E1 cells and rat organ cultures.  Eur J Pharmacol  2003  477(1):9-16  PubMed ID: 14512092   DOI: 10.1016/j.ejphar.2003.08.011
6629  Takahashi N, Udagawa N, Tanaka S, Suda T.  Generating murine osteoclasts from bone marrow.  Methods Mol Med  2003  80:129-44  PubMed ID: 12728715   DOI: 10.1385/1-59259-366-6:129
6662  Fratzl-Zelman N, Glantschnig H, Rumpler M, Nader A, Ellinger A, Varga F.  The expression of matrix metalloproteinase-13 and osteocalcin in mouse osteoblasts is related to osteoblastic differentiation and is modulated by 1,25-dihydroxyvitamin D3 and thyroid hormones.  Cell Biol Int  2003  27(6):459-68  PubMed ID: 12798773   DOI: 10.1016/s1065-6995(03)00037-4
6696  Maeda T, Kawane T, Horiuchi N.  Statins augment vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation.  Endocrinology  2003  144(2):681-92  PubMed ID: 12538631   DOI: 10.1210/en.2002-220682
6697  Ding J, Nagai K, Woo JT.  Insulin-dependent adipogenesis in stromal ST2 cells derived from murine bone marrow.  Biosci Biotechnol Biochem  2003  67(2):314-21  PubMed ID: 12728992   DOI: 10.1271/bbb.67.314
6704  Ha H, Ho J, Shin S, Kim H, Koo S, Kim IH, Kim C.  Effects of Eucommiae Cortex on osteoblast-like cell proliferation and osteoclast inhibition.  Arch Pharm Res  2003  26(11):929-36  PubMed ID: 14661859   DOI: 10.1007/bf02980202
6707  Naruse K, Miyauchi A, Itoman M, Mikuni-Takagaki Y.  Distinct anabolic response of osteoblast to low-intensity pulsed ultrasound.  J Bone Miner Res  2003  18(2):360-9  PubMed ID: 12568414   DOI: 10.1359/jbmr.2003.18.2.360
15417  Shalhoub V, Grisanti M, Padagas J, Scully S, Rattan A, Qi M, Varnum B, Vezina C, Lacey D, Martin D.  In vitro studies with the calcimimetic, cinacalcet HCl, on normal human adult osteoblastic and osteoclastic cells  Crit Rev Eukaryot Gene Expr  2003  13(2-4):89-106  PubMed ID: 14696958   DOI: 10.1615/critreveukaryotgeneexpr.v13.i24.30
16305  Nagano M, Ryu BY, Brinster CJ, Avarbock MR, Brinster RL.  Maintenance of mouse male germ line stem cells in vitro  Biol Reprod  2003  68(6):2207-14  PubMed ID: 12606373   DOI: 10.1095/biolreprod.102.014050
2518  Yoneda S, Itoh D, Kuroda S, Kondo H, Umezawa A, Ohya K, Ohyama T, Kasugai S.  The effects of enamel matrix derivative (EMD) on osteoblastic cells in culture and bone regeneration in a rat skull defect  J Periodontal Res  2003  38(3):333-42  PubMed ID: 12753373   DOI: 10.1034/j.1600-0765.2003.00667.x
2773  Sakiyama H, Nonaka T, Masuda R, Inoue N, Kuboki Y, Iijima M, Hirabayasi Y, Takahagi M, Yoshida K, Kuriiwa K, Yoshida M, Imajoh-Ohmi S  Characterization of mineral deposits formed in cultures of a hamster tartrate-resistant acid phosphatase (TRAP) and alkaline phosphatase (ALP) double-positive cell line (CCP).  Cell Tissue Res  2002  309:269-79  PubMed ID: 12172786   DOI: 10.1007/s00441-002-0587-y
2546  Kitazawa, Riko, Kitazawa, Sohei  Vitamin D(3) augments osteoclastogenesis via vitamin D-responsive element of mouse RANKL gene promoter.  Biochem Biophys Res Commun  2002  290:650-5  PubMed ID: 11785948   DOI: 10.1006/bbrc.2001.6251
3000  Sakuta K, Sakai H, Mori H, Morihata H, Kuno M  Na+ dependence of extracellular Ca2+-sensing mechanisms leading to activation of an outwardly rectifying Cl- channel in murine osteoclasts.  Bone  2002  31:374-80  PubMed ID: 12231409   DOI: 10.1016/s8756-3282(02)00838-4
2999  Sakuta, Koichi, Morihata, Hirokazu, Mori, Hiroyuki, Sakai, Hiromu, Kuno, Miyuki  Cell swelling as an intermediate signal leading to activation of a Cl- channel in extracellular calcium-sensing of murine osteoclasts.  Osaka City Med J  2002  48:29-38  PubMed ID: 12375695  
3582  Miura M, Tanaka K, Komatsu Y, Suda M, Yasoda A, Sakuma Y, Ozasa A, Nakao K.  A novel interaction between thyroid hormones and 1,25(OH)(2)D(3) in osteoclast formation.  Biochem Biophys Res Commun  2002  291(4):987-94  PubMed ID: 11866463   DOI: 10.1006/bbrc.2002.6561
6673  Kuriyama K, Higuchi C, Tanaka K, Yoshikawa H, Itoh K.  A novel anti-rheumatic drug, T-614, stimulates osteoblastic differentiation in vitro and bone morphogenetic protein-2-induced bone formation in vivo.  Biochem Biophys Res Commun  2002  299(5):903-9  PubMed ID: 12470665   DOI: 10.1016/s0006-291x(02)02754-7
6675  Tsutsumimoto T, Wakabayashi S, Kinoshita T, Horiuchi H, Takaoka K.  A phosphodiesterase inhibitor, pentoxifylline, enhances the bone morphogenetic protein-4 (BMP-4)-dependent differentiation of osteoprogenitor cells.  Bone  2002  31(3):396-401  PubMed ID: 12231412   DOI: 10.1016/s8756-3282(02)00839-6
6679  Hinoi E, Fujimori S, Takemori A, Yoneda Y.  Cell death by pyruvate deficiency in proliferative cultured calvarial osteoblasts.  Biochem Biophys Res Commun  2002  294(5):1177-83  PubMed ID: 12074601   DOI: 10.1016/S0006-291X(02)00578-8
6684  Kitazawa S, Kitazawa R.  Epigenetic control of mouse receptor activator of NF-kappa B ligand gene expression.  Biochem Biophys Res Commun  2002  293(1):126-31  PubMed ID: 12054573   DOI: 10.1016/S0006-291X(02)00189-4
6692  Wakabayashi S, Tsutsumimoto T, Kawasaki S, Kinoshita T, Horiuchi H, Takaoka K.  Involvement of phosphodiesterase isozymes in osteoblastic differentiation.  J Bone Miner Res  2002  17(2):249-56  PubMed ID: 11811555   DOI: 10.1359/jbmr.2002.17.2.249
6693  Takeuchi Y, Watanabe S, Ishii G, Takeda S, Nakayama K, Fukumoto S, Kaneta Y, Inoue D, Matsumoto T, Harigaya K, Fujita T.  Interleukin-11 as a stimulatory factor for bone formation prevents bone loss with advancing age in mice.  J Biol Chem  2002  277(50):49011-8  PubMed ID: 12384500   DOI: 10.1074/jbc.M207804200
6698  Goseki-Sone M, Yamada A, Hamatani R, Mizoi L, Iimura T, Ezawa I.  Phosphate depletion enhances bone morphogenetic protein-4 gene expression in a cultured mouse marrow stromal cell line ST2.  Biochem Biophys Res Commun  2002  ;299(3):395-9  PubMed ID: 12445813   DOI: 10.1016/s0006-291x(02)02646-3
6699  Tang L, Ebara S, Kawasaki S, Wakabayashi S, Nikaido T, Takaoka K.  FK506 enhanced osteoblastic differentiation in mesenchymal cells.  Cell Biol Int  2002  26(1):75-84  PubMed ID: 11779223   DOI: 10.1006/cbir.2001.0812
6700  Mikuni-Takagaki Y, Naruse K, Azuma Y, Miyauchi A.  The role of calcium channels in osteocyte function.  J Musculoskelet Neuronal Interact  2002  2(3):252-5  PubMed ID: 15758446  
6702  Okazaki R, Inoue D, Shibata M, Saika M, Kido S, Ooka H, Tomiyama H, Sakamoto Y, Matsumoto T.  Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) alpha or beta.  Endocrinology  2002  143(6):2349-56  PubMed ID: 12021200   DOI: 10.1210/endo.143.6.8854
17294  Tintut Y, Parhami F, Tsingotjidou A, Tetradis S, Territo M, Demer LL.  8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway  J Biol Chem  2002  277(16):14221-6  PubMed ID: 11827970   DOI: 10.1074/jbc.M111551200
17296  Rubin J, Ackert-Bicknell CL, Zhu L, Fan X, Murphy TC, Nanes MS, Marcus R, Holloway L, Beamer WG, Rosen CJ.  IGF-I regulates osteoprotegerin (OPG) and receptor activator of nuclear factor-kappaB ligand in vitro and OPG in vivo  J Clin Endocrinol Metab  2002  87(9):4273-9  PubMed ID: 12213884   DOI: 10.1210/jc.2002-020656
17299  Ishida A, Fujita N, Kitazawa R, Tsuruo T.  Transforming growth factor-beta induces expression of receptor activator of NF-kappa B ligand in vascular endothelial cells derived from bone  J Biol Chem  2002  277(29):26217-24  PubMed ID: 12011070   DOI: 10.1074/jbc.M111093200
2771  Sakiyama H, Masuda R, Inoue N, Yamamoto K, Kuriiwa K, Nakagawa K, Yoshida K  Establishment and characterization of macrophage-like cell lines expressing osteoclast-specific markers.  J Bone Miner Metab  2001  19:220-7  PubMed ID: 11448014   DOI: 10.1007/s007740170024
2772  Masuda R, Sakiyama H, Nonaka T, Kwan A, Nakagawa K, Moriya H, Imajoh-Ohmi S, Honjo M, Yoshida K  Establishment and characterization of tartrate-resistant acid phosphatase and alkaline phosphatase double positive cell lines.  Cell Tissue Res  2001  304:351-9  PubMed ID: 11456411   DOI: 10.1007/s004410100347
6657  Kikuchi T, Matsuguchi T, Tsuboi N, Mitani A, Tanaka S, Matsuoka M, Yamamoto G, Hishikawa T, Noguchi T, Yoshikai Y.  Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors.  J Immunol  2001  166(5):3574-9  PubMed ID: 11207318   DOI: 10.4049/jimmunol.166.5.3574
6663  Yamagishi T, Otsuka E, Hagiwara H.  Reciprocal control of expression of mRNAs for osteoclast differentiation factor and OPG in osteogenic stromal cells by genistein: evidence for the involvement of topoisomerase II in osteoclastogenesis.  Endocrinology  2001  142(8):3632-7  PubMed ID: 11459812   DOI: 10.1210/endo.142.8.8310
6666  Ding J, Woo JT, Nagai K.  The effects of retinoic acid on reversing the adipocyte differentiation into an osteoblastic tendency in ST2 cells, a murine bone marrow-derived stromal cell line.  Cytotechnology  2001  36(1-3):125-36  PubMed ID: 19003323   DOI: 10.1023/A:1014056012278
16947  Fan X, Fan D, Gewant H, Royce CL, Nanes MS, Rubin J.  Increasing membrane-bound MCSF does not enhance OPGL-driven osteoclastogenesis from marrow cells  Am J Physiol Endocrinol Metab  2001  280(1):E103-11.  PubMed ID: 11120664   DOI: 10.1152/ajpendo.2001.280.1.E103
16962  Yano K, Shibata O, Mizuno A, Kobayashi F, Higashio K, Morinaga T, Tsuda E.  Immunological study on circulating murine osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF): possible role of OPG/OCIF in the prevention of osteoporosis in pregnancy  Biochem Biophys Res Commun  2001  288(1):217-24  PubMed ID: 11594776   DOI: 10.1006/bbrc.2001.5745
2430  Otsuka E, Kato Y, Hirose S, Hagiwara H  Role of ascorbic acid in the osteoclast formation: induction of osteoclast differentiation factor with formation of the extracellular collagen matrix.  Endocrinology  2000  141:3006-11  PubMed ID: 10919289   DOI: 10.1210/endo.141.8.7597
5400  Kawaguchi N, Noda M.  Mitf is expressed in osteoclast progenitors in vitro.  Exp Cell Res  2000  260(2):284-91  PubMed ID: 11035923   DOI: 10.1006/excr.2000.5020
3984  Naruse K, Mikuni-Takagaki Y, Azuma Y, Ito M, Oota T, Kameyama K, Itoman M.  Anabolic response of mouse bone-marrow-derived stromal cell clone ST2 cells to low-intensity pulsed ultrasound.  Biochem Biophys Res Commun  2000  268(1):216-20  PubMed ID: 10652238   DOI: 10.1006/bbrc.2000.2094
3987  Gruber R, Nothegger G, Ho GM, Willheim M, Peterlik M.  Differential stimulation by PGE(2) and calcemic hormones of IL-6 in stromal/osteoblastic cells.  Biochem Biophys Res Commun  2000  270(3):1080-5  PubMed ID: 10772953   DOI: 10.1006/bbrc.2000.2573
3988  Koyama A, Otsuka E, Inoue A, Hirose S, Hagiwara H.  Nitric oxide accelerates the ascorbic acid-induced osteoblastic differentiation of mouse stromal ST2 cells by stimulating the production of prostaglandin E(2).  Eur J Pharmacol  2000  391(3):225-31  PubMed ID: 10729362   DOI: 10.1016/s0014-2999(00)00100-x
3990  Takami M, Takahashi N, Udagawa N, Miyaura C, Suda K, Woo JT, Martin TJ, Nagai K, Suda T.  Intracellular calcium and protein kinase C mediate expression of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in osteoblasts.  Endocrinology  2000  141(12):4711-9  PubMed ID: 11108286   DOI: 10.1210/endo.141.12.7852
3996  Takeuchi Y, Suzawa M, Fukumoto S, Fujita T.  Vitamin K(2) inhibits adipogenesis, osteoclastogenesis, and ODF/RANK ligand expression in murine bone marrow cell cultures.  Bone  2000  27(6):769-76  PubMed ID: 11113387   DOI: 10.1016/s8756-3282(00)00396-3
13683  Michigami T, Shimizu N, Williams PJ, Niewolna M, Dallas SL, Mundy GR, Yoneda T.  Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4)beta(1)-integrin enhances production of osteoclast-stimulating activity  Blood  2000  96(5):1953-60.  PubMed ID: 10961900  
1898  Nakashima T, Kobayashi Y, Yamasaki S, Kawakami A, Eguchi K, Sasaki H, Sakai H.  Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokines  Biochem Biophys Res Commun  2000  275(3):768-75  PubMed ID: 10973797   DOI: 10.1006/bbrc.2000.3379
2998  Sakai H, Nakamura F, Kuno M  Synergetic activation of outwardly rectifying Cl- currents by hypotonic stress and external Ca2+ in murine osteoclasts  J Physiol  1999  515:157-168  PubMed ID: 9925886   DOI: 10.1111/j.1469-7793.1999.157ad.x
2545  Kitazawa R, Kitazawa S, Maeda S  Promoter structure of mouse RANKL/TRANCE/OPGL/ODF gene.  Biochim Biophys Acta  1999  1445:134-41  PubMed ID: 10209265   DOI: 10.1016/s0167-4781(99)00032-9
2370  Otsuka E, Yamaguchi A, Hirose S, Hagiwara H  Characterization of osteoblastic differentiation of stromal cell line ST2 that is induced by ascorbic acid  Am J Physiol  1999  277(1 Pt 1):132-138  PubMed ID: 10409116   DOI: 10.1152/ajpcell.1999.277.1.C132
2420  Yuhara S, Kasagi S, Inoue A, Otsuka E, Hirose S, Hagiwara H  Effects of nicotine on cultured cells suggest that it can influence the formation and resorption of bone.  Eur J Pharmacol  1999  383:387-93  PubMed ID: 10594333   DOI: 10.1016/s0014-2999(99)00551-8
5398  Shalhoub V, Faust J, Boyle WJ, Dunstan CR, Kelley M, Kaufman S, Scully S, Van G, Lacey DL.  Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formation from human peripheral blood mononuclear cell precursors.  J Cell Biochem  1999  72(2):251-61  PubMed ID: 10022507  
3960  Fujiwara M, Tagashira S, Harada H, Ogawa S, Katsumata T, Nakatsuka M, Komori T, Takada H.  Isolation and characterization of the distal promoter region of mouse Cbfa1.  Biochim Biophys Acta  1999  1446(3):265-72  PubMed ID: 10524201   DOI: 10.1016/s0167-4781(99)00113-x
3964  Nagai M, Sato N.  Reciprocal gene expression of osteoclastogenesis inhibitory factor and osteoclast differentiation factor regulates osteoclast formation.  Biochem Biophys Res Commun  1999  257(3):719-23  PubMed ID: 10208850   DOI: 10.1006/bbrc.1999.0524
3967  Tomohiro ShimizuJe-Tae WooKazuo Nagai  Screening for Bioactive Compounds that Induce the Differentiation of Bone Marrow-Derived Preadipocytic Cell Line, ST2, into the Cells of Osteoblastic Phenotype  Animal Cell Technology: Basic & Applied Aspects  1999  10:353–356    DOI: 10.1007/0-306-46865-4_61
3973  Goseki-Sone M, Yamada A, Asahi K, Hirota A, Ezawa I, Iimura T.  Phosphate depletion enhances tissue-nonspecific alkaline phosphatase gene expression in a cultured mouse marrow stromal cell line ST2.  Biochem Biophys Res Commun  1999  265(1):24-8  PubMed ID: 10548485   DOI: 10.1006/bbrc.1999.1624
3529  Quinn JM, Morfis M, Lam MH, Elliott J, Kartsogiannis V, Williams ED, Gillespie MT, Martin TJ, Sexton PM.  Calcitonin receptor antibodies in the identification of osteoclasts.  Bone  1999  25(1):1-8  PubMed ID: 10423015   DOI: 10.1016/s8756-3282(99)00094-0
6648  Isaacs SD, Fan X, Fan D, Gewant H, Murphy TC, Farmer P, Taylor WR, Nanes MS, Rubin J.  Role of NFkappaB in the regulation of macrophage colony stimulating factor by tumor necrosis factor-alpha in ST2 bone stromal cells.  J Cell Physiol  1999  179(2):193-200  PubMed ID: 10199558   DOI: 10.1002/(SICI)1097-4652(199905)179:2<193::AID-JCP9>3.0.CO;2-3
13802  Yano K, Tsuda E, Washida N, Kobayashi F, Goto M, Harada A, Ikeda K, Higashio K, Yamada Y.  Immunological characterization of circulating osteoprotegerin/osteoclastogenesis inhibitory factor: increased serum concentrations in postmenopausal women with osteoporosis  J Bone Miner Res  1999  14(4):518-27  PubMed ID: 10234572   DOI: 10.1359/jbmr.1999.14.4.518
2274  Nishikawa M, Yamamoto M, Murakami T, Akatsu T, Kugai N, Nagata N  A third-generation bisphosphonate, YM175, inhibits osteoclast formation in murine cocultures by inhibiting proliferation of precursor cells via supporting cell-dependent mechanisms.  J Bone Miner Res  1998  13:986-95  PubMed ID: 9626630   DOI: 10.1359/jbmr.1998.13.6.986
3943  Murakami T, Yamamoto M, Ono K, Nishikawa M, Nagata N, Motoyoshi K, Akatsu T.  Transforming growth factor-beta1 increases mRNA levels of osteoclastogenesis inhibitory factor in osteoblastic/stromal cells and inhibits the survival of murine osteoclast-like cells.  Biochem Biophys Res Commun.   1998  252(3):747-52  PubMed ID: 9837778   DOI: 10.1006/bbrc.1998.9723
3947  Takai H, Kanematsu M, Yano K, Tsuda E, Higashio K, Ikeda K, Watanabe K, Yamada Y.  Transforming growth factor-beta stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells.  J Biol Chem  1998  273(42):27091-6  PubMed ID: 9765225   DOI: 10.1074/jbc.273.42.27091
3949  Yasuda H, Shima N, Nakagawa N, Mochizuki SI, Yano K, Fujise N, Sato Y, Goto M, Yamaguchi K, Kuriyama M, Kanno T, Murakami A, Tsuda E, Morinaga T, Higashio K.  Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro.  Endocrinology.  1998  139(3):1329-37  PubMed ID: 9492069   DOI: 10.1210/endo.139.3.5837
3950  Yamaguchi T, Chattopadhyay N, Kifor O, Brown EM.  Extracellular calcium (Ca2+(o))-sensing receptor in a murine bone marrow-derived stromal cell line (ST2): potential mediator of the actions of Ca2+(o) on the function of ST2 cells.  Endocrinology  1998  139(8):3561-8  PubMed ID: 9681508   DOI: 10.1210/endo.139.8.6163
3951  Harada H, Kuboi Y, Miki R, Honda C, Masushige S, Nakatsuka M, Koga Y, Kato S.  Cloning of rabbit TR4 and its bone cell-specific activity to suppress estrogen receptor-mediated transactivation.  Endocrinology  1998  139(1):204-12  PubMed ID: 9421416   DOI: 10.1210/endo.139.1.5682
9167  K N Weilbaecher, C L Hershey, C M Takemoto, M A Horstmann, T J Hemesath, A H Tashjian, D E Fisher  Age-resolving Osteopetrosis: A Rat Model Implicating Microphthalmia and the Related Transcription Factor TFE3  J Exp Med  1998  187 (5), 775-85  PubMed ID: 9480987   DOI: 10.1084/jem.187.5.775
13808  Ragab AA, Lavish SA, Banks MA, Goldberg VM, Greenfield EM.  Osteoclast differentiation requires ascorbic acid  J Bone Miner Res  1998  13(6):970-7  PubMed ID: 9626628   DOI: 10.1359/jbmr.1998.13.6.970
15428  Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, Elliott R, Colombero A, Elliott G, Scully S, Hsu H, Sullivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian YX, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J, Boyle WJ.  Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation  Cell   1998  93(2):165-76  PubMed ID: 9568710   DOI: 10.1016/s0092-8674(00)81569-x
16637  Yamaguchi K, Kinosaki M, Goto M, Kobayashi F, Tsuda E, Morinaga T, Higashio K.  Characterization of structural domains of human osteoclastogenesis inhibitory factor.  J Biol Chem  1998  273:5117-23  PubMed ID: 9478964   DOI: 10.1074/jbc.273.9.5117
1089  Takase M, Imamura T, Sampath TK, Takeda K, Ichijo H, Miyazono K, Kawabata M.  Induction of Smad6 mRNA by bone morphogenetic proteins  Biochem Biophys Res Commun  1998  244(1):26-9  PubMed ID: 9514869   DOI: 10.1006/bbrc.1998.8200
1139  Takeda K, Ichijo H, Fujii M, Mochida Y, Saitoh M, Nishitoh H, Sampath TK, Miyazono K.  Identification of a novel bone morphogenetic protein-responsive gene that may function as a noncoding RNA  J Biol Chem  1998  273(27):17079-85  PubMed ID: 9642273   DOI: 10.1074/jbc.273.27.17079
1210  Breuil V, Cosman F, Stein L, Horbert W, Nieves J, Shen V, Lindsay R, Dempster DW.  Human osteoclast formation and activity in vitro: effects of alendronate  J Bone Miner Res  1998  13(11):1721-9.  PubMed ID: 9797481   DOI: 10.1359/jbmr.1998.13.11.1721
1292  Muguruma Y, Lee MY.  Isolation and characterization of murine clonogenic osteoclast progenitors by cell surface phenotype analysis  Blood  1998  91(4):1272-9  PubMed ID: 9454757  
1312  Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, Mochizuki S, Tomoyasu A, Yano K, Goto M, Murakami A, Tsuda E, Morinaga T, Higashio K, Udagawa N, Takahashi N, Suda T.  Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL  Proc Natl Acad Sci U S A   1998  95(7):3597-602  PubMed ID: 9520411   DOI: 10.1073/pnas.95.7.3597
2997  Shibata T, Sakai H, Nakamura F, Shioi A, Kuno M  Differential effect of high extracellular Ca2+ on K+ and Cl- conductances in murine osteoclasts.  J Membr Biol  1997  158:59-67  PubMed ID: 9211721   DOI: 10.1007/s002329900243
18049  Wakikawa T, Shioi A, Hino M, Inaba M, Nishizawa Y, Tatsumi N, Morii H, Otani S.  Thrombopoietin inhibits in vitro osteoclastogenesis from murine bone marrow cells  Endocrinology  1997  138(10):4160-6  PubMed ID: 9322925   DOI: 10.1210/endo.138.10.5438
18082  Kania JR, Kehat-Stadler T, Kupfer SR.  CD44 antibodies inhibit osteoclast formation  J Bone Miner Res  1997  12(8):1155-64  PubMed ID: 9258745   DOI: 10.1359/jbmr.1997.12.8.1155
3938  Tsuda E, Goto M, Mochizuki S, Yano K, Kobayashi F, Morinaga T, Higashio K.  Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis.  Biochem Biophys Res Commun  1997  234(1):137-42  PubMed ID: 9168977   DOI: 10.1006/bbrc.1997.6603
3939  Natsume T, Tomita S, Iemura S, Kinto N, Yamaguchi A, Ueno N.  Interaction between soluble type I receptor for bone morphogenetic protein and bone morphogenetic protein-4.  J Biol Chem  1997  272(17):11535-40  PubMed ID: 9111068   DOI: 10.1074/jbc.272.17.11535
1600  Quinn JM, Sabokbar A, Denne M, de Vernejoul MC, McGee JO, Athanasou NA.  Inhibitory and stimulatory effects of prostaglandins on osteoclast differentiation  Calcif Tissue Int   1997  60(1):63-70  PubMed ID: 9030482   DOI: 10.1007/s002239900187
2065  Jimi E, Shuto T, Ikebe T, Jingushi S, Hirata M, Koga T  Basic fibroblast growth factor inhibits osteoclast-like cell formation.  J Cell Physiol  1996  168:395-402  PubMed ID: 8707875   DOI: 10.1002/(SICI)1097-4652(199608)168:2<395::AID-JCP18>3.0.CO;2-2
17997  Clohisy DR, Ogilvie CM, Carpenter RJ, Ramnaraine ML.  Localized, tumor-associated osteolysis involves the recruitment and activation of osteoclasts  J Orthop Res  1996  14(1):2-6  PubMed ID: 8618161   DOI: 10.1002/jor.1100140103
4868  Romas E, Udagawa N, Zhou H, Tamura T, Saito M, Taga T, Hilton DJ, Suda T, Ng KW, Martin TJ.  The role of gp130-mediated signals in osteoclast development: regulation of interleukin 11 production by osteoblasts and distribution of its receptor in bone marrow cultures.  J Exp Med  1996  183(6):2581-91  PubMed ID: 8676079   DOI: 10.1084/jem.183.6.2581
3926  Jimi E, Nakamura I, Amano H, Taguchi Y, Tsurukai T, Tamura M, Takahashi N, Suda T.  Osteoclast function is activated by osteoblastic cells through a mechanism involving cell-to-cell contact.  Endocrinology.  1996  137(8):2187-90  PubMed ID: 8754795   DOI: 10.1210/endo.137.8.8754795
3927  Yamaguchi 1, Ishizuya T, Kintou N, Wada Y, Katagiri T, Wozney JM, Rosen V, Yoshiki S.  Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow-derived stromal cell lines, ST2 and MC3T3-G2/PA6.  Biochem Biophys Res Commun  1996  220(2):366-71  PubMed ID: 8645311   DOI: 10.1006/bbrc.1996.0411
17218  Fujikawa Y, Quinn JM, Sabokbar A, McGee JO, Athanasou NA.  The human osteoclast precursor circulates in the monocyte fraction  Endocrinology  1996  137(9):4058-60  PubMed ID: 8756585   DOI: 10.1210/endo.137.9.8756585
2064  Jimi E, Shuto T, Koga T  Macrophage colony-stimulating factor and interleukin-1 alpha maintain the survival of osteoclast-like cells.  Endocrinology  1995  136:808-11  PubMed ID: 7835314   DOI: 10.1210/endo.136.2.7835314
17981  Perkins SL, Kling SJ.  Local concentrations of macrophage colony-stimulating factor mediate osteoclastic differentiation  Am J Physiol   1995  269(6 Pt 1):E1024-30  PubMed ID: 8572192   DOI: 10.1152/ajpendo.1995.269.6.E1024
3975  Lacey DL, Erdmann JM, Teitelbaum SL, Tan HL, Ohara J, Shioi A.  Interleukin 4, interferon-gamma, and prostaglandin E impact the osteoclastic cell-forming potential of murine bone marrow macrophages  Endocrinology  1995  2367-76  PubMed ID: 7750457   DOI: 10.1210/endo.136.6.7750457
3079  Shuto T, Jimi E, Kukita T, Hirata M, Koga T  Granulocyte-macrophage colony stimulating factor suppresses lipopolysaccharide-induced osteoclast-like cell formation in mouse bone marrow cultures.  Endocrinology  1994  134:831-7  PubMed ID: 8299579   DOI: 10.1210/endo.134.2.8299579
17928  Lacey DL, Erdmann JM, Tan HL.  Interleukin 4 increases type 5 acid phosphatase mRNA expression in murine bone marrow macrophages  J Cell Biochem  1994  54(3):365-71  PubMed ID: 8200916   DOI: 10.1002/jcb.240540312
17929  Shioi A, Ross FP, Teitelbaum SL.  Enrichment of generated murine osteoclasts  Calcif Tissue Int  1994  55(5):387-94  PubMed ID: 7532541   DOI: 10.1007/BF00299320
10123  Baskin LS, Duckett JW.  Dorsal tunica albuginea plication for hypospadias curvature.  J. Urol.  1994  151:1668-71  PubMed ID: 8189595   DOI: 10.1016/s0022-5347(17)35341-7
15411  Quinn JM, McGee JO, Athanasou NA.  Cellular and hormonal factors influencing monocyte differentiation to osteoclastic bone-resorbing cells  Endocrinology  1994  134(6):2416-23  PubMed ID: 8194468   DOI: 10.1210/endo.134.6.8194468
1513  Flanagan, A M, Horton, M A, Dorey, E L, Collins, D A, Evely, R S, Moseley, J M, Firkin, F C, Chambers, T J, Helfrich, M H, Martin, T J  An assessment of the ability of human bone marrow cultures to generate osteoclasts.  Int J Exp Pathol  1992  73:387-401  PubMed ID: 1320395  
1512  Athanasou, N A, Quinn, J M  Human tumour-associated macrophages are capable of bone resorption.  Br J Cancer  1992  65:523-6  PubMed ID: 1562461   DOI: 10.1038/bjc.1992.108
1515  Kerby, J A, Hattersley G, Collins, D A, Chambers, T J  Derivation of osteoclasts from hematopoietic colony-forming cells in culture.  J Bone Miner Res  1992  7:353-62  PubMed ID: 1585838   DOI: 10.1002/jbmr.5650070316
17894  Quinn JM, Athanasou NA.  Tumour infiltrating macrophages are capable of bone resorption  J Cell Sci  1992  101 ( Pt 3):681-6  PubMed ID: 1522150   DOI: 10.1242/jcs.101.3.681
17895  Collins DA, Chambers TJ.  Prostaglandin E2 promotes osteoclast formation in murine hematopoietic cultures through an action on hematopoietic cells  J Bone Miner Res  1992  7(5):555-61  PubMed ID: 1615762   DOI: 10.1002/jbmr.5650070512
17896  Wang ZQ, Hemken P, Menton D, Gluck S.  Expression of vacuolar H(+)-ATPase in mouse osteoclasts during in vitro differentiation  Am J Physiol  1992  263(2 Pt 2):F277-83  PubMed ID: 1387291   DOI: 10.1152/ajprenal.1992.263.2.F277
10334  J Quinn, C Joyner, J T Triffitt, N A Athanasou  Polymethylmethacrylate-induced Inflammatory Macrophages Resorb Bone  J Bone Joint Surg Br  1992  74(5):652-8  PubMed ID: 1527108   DOI: 10.1302/0301-620X.74B5.1527108
1514  Shioi A, Teitelbaum, S L, Ross, F P, Welgus, H G, Suzuki H, Ohara J, Lacey, D L  Interleukin 4 Inhibits Murine Osteoclast Formation In Vitro  J Cell Biol  1991  47:272-277  PubMed ID: 1665152   DOI: 10.1002/jcb.240470313
1431  Hong, M H, Jin, C H, Sato T, Ishimi Y, Abe E, Suda T  Transcriptional regulation of the production of the third component of complement (C3) by 1 alpha,25-dihydroxyvitamin D3 in mouse marrow-derived stromal cells (ST2) and primary osteoblastic cells.  Endocrinology  1991  129:2774-9  PubMed ID: 1935807   DOI: 10.1210/endo-129-5-2774
1382  Sato T, Hong, M H, Jin, C H, Ishimi Y, Udagawa N, Shinki T, Abe E, Suda T  The specific production of the third component of complement by osteoblastic cells treated with 1 alpha,25-dihydroxyvitamin D3.  FEBS Lett  1991  285:21-4  PubMed ID: 2065778   DOI: 10.1016/0014-5793(91)80715-f
1330  Udagawa N, Takahashi N, Akatsu T, Tanaka H, Sasaki T, Nishihara T, Koga T, Martin, T J, Suda T  Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells.  Proc Natl Acad Sci U S A  1990  87:7260-4  PubMed ID: 2169622   DOI: 10.1073/pnas.87.18.7260
1327  Udagawa N, Takahashi N, Akatsu T, Sasaki T, Yamaguchi A, Kodama H, Martin, T J, Suda T  The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells.  Endocrinology  1989  125:1805-13  PubMed ID: 2676473   DOI: 10.1210/endo-125-4-1805

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13576  小林 真左子, 河野 通秀, 永井 孝宏, 片桐 浩樹, 飯塚 建行  各種骨補填材におけるマクロファージ・骨芽細胞分化能およびBone Morphogenetic Protein-2の担体としての有用性に関するin vitro評価  日本口腔外科学会雑誌  2020  66:586-595    DOI: 10.5794/jjoms.66.586
1756  左右田 昌彦、小山 洋一、丸野内 棣  マクロファージ系株細胞(J774-1)の分化に対するB細胞ハイブリドーマ培養上清の阻害作用  藤田学園医学会誌  1992  16:75-80   



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