CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [RCB0224 : ST2]

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13151 Cornelis R, Hahne S, Taddeo A, Petkau G, Malko D, Durek P, Thiem M, Heiberger L, Peter L, Mohr E, Klaeden C, Tokoyoda K, Siracusa F, Hoyer BF, Hiepe F, Mashreghi MF, Melchers F, Chang HD, Radbruch A. Stromal Cell-Contact Dependent PI3K and APRIL Induced NF-κB Signaling Prevent Mitochondrial- and ER Stress Induced Death of Memory Plasma Cells. Cell Rep 2020 PubMed ID: 32755576 DOI: 10.1016/j.celrep.2020.107982

13197 Yahiro Y, Maeda S, Morikawa M, Koinuma D, Jokoji G, Ijuin T, Komiya S, Kageyama R, Miyazono K, Taniguchi N. BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts. Bone Res 2020 PubMed ID: 32923015 DOI: 10.1038/s41413-020-00106-0

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14500 Asparuhova MB, Chappuis V, Stähli A, Buser D, Sculean A. Role of hyaluronan in regulating self-renewal and osteogenic differentiation of mesenchymal stromal cells and pre-osteoblasts Clin Oral Investig 2020 24(11):3923-3937 PubMed ID: 32236725 DOI: 10.1007/s00784-020-03259-8

11318 Hagiwara H, Nakata K, Miyazaki H, Maehashi S, Komiyama Y, Aida R, Yoshida S, Kokubu D, Hagiwara K, Yoshida K. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation. Cytotechnology 2019 PubMed ID: 30474804 DOI: 10.1007/s10616-018-0236-2

11323 Yu J, Kim HM, Kim KP, Son Y, Kim MS, Park KS. Ceramide kinase regulates the migration of bone marrow-derived mesenchymal stem cells. Biochem. Biophys. Res. Commun. 2019 PubMed ID: 30502084 DOI: 10.1016/j.bbrc.2018.11.154

11366 Yang X, Wang G, Wang Y, Zhou J, Yuan H, Li X, Liu Y, Wang B. Histone demethylase KDM7A reciprocally regulates adipogenic and osteogenic differentiation via regulation of C/EBPα and canonical Wnt signalling. J. Cell. Mol. Med. 2019 PubMed ID: 30614617 DOI: 10.1111/jcmm.14126

11439 Yu Y, Newman H, Shen L, Sharma D, Hu G, Mirando AJ, Zhang H, Knudsen E, Zhang GF, Hilton MJ, Karner CM. Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells. Cell Metab. 2019 PubMed ID: 30773468 DOI: 10.1016/j.cmet.2019.01.016

11460 Strauss FJ, Di Summa F, Stähli A, Matos L, Vaca F, Schuldt G, Gruber R. TGF-β activity in acid bone lysate adsorbs to titanium surface. Clin Implant Dent Relat Res 2019 PubMed ID: 30817088 DOI: 10.1111/cid.12734

11607 Kusuyama J, Seong C, Makarewicz NS, Ohnishi T, Shima K, Semba I, Bandow K, Matsuguchi T. Low intensity pulsed ultrasound (LIPUS) maintains osteogenic potency by the increased expression and stability of Nanog through spleen tyrosine kinase (Syk) activation. Cell. Signal. 2019 PubMed ID: 31228531 DOI: 10.1016/j.cellsig.2019.109345

11659 Jin‐Ran Chen, Umesh D Wankhade, Alexander W Alund, Michael L Blackburn, Kartik Shankar, Oxana P Lazarenko 3‐(3‐Hydroxyphenyl)‐Propionic Acid (PPA) Suppresses Osteoblastic Cell Senescence to Promote Bone Accretion in Mice JBMR Plus 2019 PubMed ID: 31667457 DOI: 10.1002/jbm4.10201

11813 Böhm AM, Dirckx N, Tower RJ, Peredo N, Vanuytven S, Theunis K, Nefyodova E, Cardoen R, Lindner V, Voet T, Van Hul M, Maes C. Activation of Skeletal Stem and Progenitor Cells for Bone Regeneration Is Driven by PDGFRβ Signaling. Dev. Cell 2019 PubMed ID: 31543445 DOI: 10.1016/j.devcel.2019.08.013

11856 Hamaya E, Fujisawa T, Tamura M. Osteoadherin serves roles in the regulation of apoptosis and growth in MC3T3‑E1 osteoblast cells. Int. J. Mol. Med. 2019 PubMed ID: 31638177 DOI: 10.3892/ijmm.2019.4376

11883 Conaway HH, Henning P, Lie A, Tuckermann J, Lerner UH. Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D3 and parathyroid hormone-induced osteoclastogenesis. FASEB J. 2019 PubMed ID: 31675485 DOI: 10.1096/fj.201802729RRR

6927 Persson E, Souza PPC, Floriano-Marcelino T, Conaway HH, Henning P, Lerner UH.Front Immunol. 2019 May 28;10:1164. doi: 10.3389/fimmu.2019.01164. eCollection 2019. Activation of Shc1 Allows Oncostatin M to Induce RANKL and Osteoclast Formation More Effectively Than Leukemia Inhibitory Factor. Front Immunol 2019 2019 May 28;10:1164 PubMed ID: 31191537 DOI: 10.3389/fimmu.2019.01164

6935 SOO LENG LEE*, ZAINAL ARIFF ABDUL RAHMAN, HIDETSUGU TSUJIGIWA, MEI HAMADA, KIYOFUMI TAKABATAKE, KEISUKE NAKANO, HITOSHI NAGATSUKA & CHONG HUAT SIAR An in vitro Three-Dimensional Co-Culture System for Ameloblastoma Modelling Sains Malaysiana 2019 48(8):1697–1706 DOI: 10.17576/jsm-2019-4808-15

9727 Jinlu Dai, June Escara-Wilke, Jill M Keller, Younghun Jung, Russell S Taichman, Kenneth J Pienta, Evan T Keller Primary Prostate Cancer Educates Bone Stroma Through Exosomal Pyruvate Kinase M2 to Promote Bone Metastasis J Exp Med 2019 216(12):2883-2899 PubMed ID: 31548301 DOI: 10.1084/jem.20190158

10553 Naru Shiraishi, Risa Ishiko-Uzuka, Kenta Takahashi, Toru Ogawa, Takahisa Anada, Osamu Suzuki, Takashi Goto and Keiichi Sasaki Effect of Functionally-Graded Calcium Titanate Film, Prepared by Metal-Organic Chemical Vapor Deposition, on Titanium Implant Appl Sci 2019 9(1):172 DOI: 10.3390/app9010172

10554 Rebecca Cornelis, Stefanie Hahne, Adriano Taddeo, Georg Petkau, Darya Malko, Pawel Durek, Manja Thiem, Lukas Heiberger, Elodie Mohr, Cora Klaeden, Koji Tokoyoda, Francesco Siracusa, Bimba Franziska Hoyer, Falk Hiepe, Mir-Farzin Mashreghi, Fritz Melchers, Hyun-Dong Chang, Andreas Radbruch Stromal cell-contact dependent PI3K and APRIL induced NF-κB signaling complement each other to prevent mitochondrial- and endoplasmic reticulum stress induced cell death of bone marrow plasma cells bioRxiv 2019 November 21 DOI: 10.1101/849638

12590 Mashimo K, Tsubaki M, Takeda T, Asano R, Jinushi M, Imano M, Satou T, Sakaguchi K, Nishida S. RANKL-induced c-Src activation contributes to conventional anti-cancer drug resistance and dasatinib overcomes this resistance in RANK-expressing multiple myeloma cells Clin Exp Med 2019 19(1):133-141 PubMed ID: 30291461 DOI: 10.1007/s10238-018-0531-4

12591 Sone E, Noshiro D, Ikebuchi Y, Nakagawa M, Khan M, Tamura Y, Ikeda M, Oki M, Murali R, Fujimori T, Yoda T, Honma M, Suzuki H, Ando T, Aoki K. The induction of RANKL molecule clustering could stimulate early osteoblast differentiation Biochem Biophys Res Commun 2019 509(2):435-440 PubMed ID: 30594398 DOI: 10.1016/j.bbrc.2018.12.093

12592 Takeno A, Kanazawa I, Tanaka KI, Notsu M, Sugimoto T. Phloretin Suppresses Bone Morphogenetic Protein-2-Induced Osteoblastogenesis and Mineralization via Inhibition of Phosphatidylinositol 3-kinases/Akt Pathway Int J Mol Sci 2019 20(10):2481 PubMed ID: 31137461 DOI: 10.3390/ijms20102481

10666 Takeno A, Kanazawa I, Notsu M, Tanaka KI, Sugimoto T. Inhibition of adenosine monophosphate-activated protein kinase suppresses bone morphogenetic protein-2-induced mineralization of osteoblasts via Smad-independent mechanisms. Endocr. J. 2018 65:291-298 PubMed ID: 29249772 DOI: 10.1507/endocrj.EJ17-0229

10731 Kumeta M, Takahashi D, Takeyasu K, Yoshimura SH. Cell type-specific suppression of mechanosensitive genes by audible sound stimulation. PLoS ONE 2018 13:e0188764 PubMed ID: 29385174 DOI: 10.1371/journal.pone.0188764

10764 Takeda T, Tsubaki M, Tomonari Y, Kawashima K, Itoh T, Imano M, Satou T, Nishida S. Bavachin induces the apoptosis of multiple myeloma cell lines by inhibiting the activation of nuclear factor kappa B and signal transducer and activator of transcription 3. Biomed. Pharmacother. 2018 100:486-494 PubMed ID: 29477912 DOI: 10.1016/j.biopha.2018.02.019

10844 Takenaka Y, Mikami K, Seno S, Matsuda H. Automated transition analysis of activated gene regulation during diauxic nutrient shift in Escherichia coli and adipocyte differentiation in mouse cells. BMC Bioinformatics 2018 19:89 PubMed ID: 29745848 DOI: 10.1186/s12859-018-2072-y

11198 Ikebuchi Y, Aoki S, Honma M, Hayashi M, Sugamori Y, Khan M, Kariya Y, Kato G, Tabata Y, Penninger JM, Udagawa N, Aoki K, Suzuki H. Coupling of bone resorption and formation by RANKL reverse signalling. Nature 2018 561(7722):195-200 PubMed ID: 30185903 DOI: 10.1038/s41586-018-0482-7

11099 Asparuhova MB, Caballe-Serrano J, Buser D, Chappuis V. Bone-conditioned medium contributes to initiation and progression of osteogenesis by exhibiting synergistic TGF-β1/BMP-2 activity. Int J Oral Sci 2018 10(2):20 PubMed ID: 29895828 DOI: 10.1038/s41368-018-0021-2

11124 Kida J, Hata K, Nakamura E, Yagi H, Takahata Y, Murakami T, Maeda Y, Nishimura R. Interaction of LEF1 with TAZ is necessary for the osteoblastogenic activity of Wnt3a. Sci Rep 2018 8(1):10375 PubMed ID: 29991769 DOI: 10.1038/s41598-018-28711-4

11153 Kuroda M, Ueda K, Kioka N. Vinexin family (SORBS) proteins regulate mechanotransduction in mesenchymal stem cells. Sci Rep 2018 8(1):11581 PubMed ID: 30068914 DOI: 10.1038/s41598-018-29700-3

11193 Eppell SJ, Tong W, McMasters J, Soenjaya Y, Barbu AM, Ko A, Baskin JZ. Minor Review: An Overview of a Synthetic Nanophase Bone Substitute. Materials (Basel) 2018 11(9) PubMed ID: 30158464 DOI: 10.3390/ma11091556

4348 Kokubun K, Matsumura S, Yudasaka M, Iijima S, Shiba K. Immobilization of a carbon nanomaterial-based localized drug-release system using a bispecific material-binding peptide. Int J Nanomedicine 2018 PubMed ID: 29588591 DOI: 10.2147/IJN.S155913

4349 Takeno A, Kanazawa I, Notsu M, Tanaka KI, Sugimoto T. Phloretin Promotes Adipogenesis via Mitogen-Activated Protein Kinase Pathways in Mouse Marrow Stromal ST2 Cells. Int J Mol Sci 2018 PubMed ID: 29904032 DOI: 10.3390/ijms19061772

4350 Aoto K, Ito K, Aoki S. Complex formation between platelet-derived growth factor receptor β and transforming growth factor β receptor regulates the differentiation of mesenchymal stem cells into cancer-associated fibroblasts. Oncotarget 2018 PubMed ID: 30344924 DOI: 10.18632/oncotarget.26124

4351 Dubon MJ, Yu J, Choi S, Park KS. Transforming growth factor β induces bone marrow mesenchymal stem cell migration via noncanonical signals and N-cadherin. J. Cell. Physiol. 2018 PubMed ID: 28213973 DOI: 10.1002/jcp.25863

4502 Choi SM, Park JW. Multifunctional effects of a modification of SLA titanium implant surface with strontium-containing nanostructures on immunoinflammatory and osteogenic cell function. J Biomed Mater Res A 2018 106(12):3009-3020 PubMed ID: 30192064 DOI: 10.1002/jbm.a.36490

14552 Kota SK, Roening C, Patel N, Kota SB, Baron R. PRMT5 inhibition promotes osteogenic differentiation of mesenchymal stromal cells and represses basal interferon stimulated gene expression Bone 2018 117:37-46 PubMed ID: 30189247 DOI: 10.1016/j.bone.2018.08.025

14900 Fujioka-Kobayashi M, Abd El Raouf M, Saulacic N, Kobayashi E, Zhang Y, Schaller B, Miron RJ. Superior bone-inducing potential of rhBMP9 compared to rhBMP2 J Biomed Mater Res A 2018 106(6):1561-1574. PubMed ID: 29396910 DOI: 10.1002/jbm.a.36359

9589 Miron RJ, Fujioka-Kobayashi M, Zhang Y, Caballé-Serrano J, Shirakata Y, Bosshardt DD, Buser D, Sculean A. Osteogain improves osteoblast adhesion, proliferation and differentiation on a bovine-derived natural bone mineral. Clin Oral Implants Res 2017 28:327-333 PubMed ID: 26919609 DOI: 10.1111/clr.12802

9860 Fujioka-Kobayashi M, Schaller B, Saulacic N, Zhang Y, Miron RJ. Growth factor delivery of BMP9 using a novel natural bovine bone graft with integrated atelo-collagen type I: Biosynthesis, characterization, and cell behavior. J Biomed Mater Res A 2017 105:408-418 PubMed ID: 27699987 DOI: 10.1002/jbm.a.35921

9874 Fujioka-Kobayashi M, Mottini M, Kobayashi E, Zhang Y, Schaller B, Miron RJ. An in vitro study of fibrin sealant as a carrier system for recombinant human bone morphogenetic protein (rhBMP)-9 for bone tissue engineering. J Craniomaxillofac Surg 2017 45:27-32 PubMed ID: 27840120 DOI: 10.1016/j.jcms.2016.10.008

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10125 Fujioka-Kobayashi M, Schaller B, Saulacic N, Pippenger BE, Zhang Y, Miron RJ. Absorbable collagen sponges loaded with recombinant bone morphogenetic protein 9 induces greater osteoblast differentiation when compared to bone morphogenetic protein 2. Clin Exp Dent Res 2017 3:32-40 PubMed ID: 29744176 DOI: 10.1002/cre2.55

10316 Aikawa T, Matsubara H, Ugaji S, Shirakawa J, Nagai R, Munesue S, Harashima A, Yamamoto Y, Tsuchiya H. Contribution of methylglyoxal to delayed healing of bone injury in diabetes. Mol Med Rep 2017 16:403-409 PubMed ID: 28534951 DOI: 10.3892/mmr.2017.6589

10395 Takada H, Ibaragi S, Eguchi T, Okui T, Obata K, Masui M, Morisawa A, Takabatake K, Kawai H, Yoshioka N, Hassan NMM, Shimo T, Hu GF, Nagatsuka H, Sasaki A. Semaphorin 4D promotes bone invasion in head and neck squamous cell carcinoma. Int. J. Oncol. 2017 51:625-632 PubMed ID: 28656278 DOI: 10.3892/ijo.2017.4050

10401 Ouji Y, Sakagami M, Omori H, Higashiyama S, Kawai N, Kitahara T, Wanaka A, Yoshikawa M. Efficient induction of inner ear hair cell-like cells from mouse ES cells using combination of Math1 transfection and conditioned medium from ST2 stromal cells. Stem Cell Res 2017 23:50-56 PubMed ID: 28689068 DOI: 10.1016/j.scr.2017.06.013

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14377 Fujioka-Kobayashi M, Sawada K, Kobayashi E, Schaller B, Zhang Y, Miron RJ. Osteogenic potential of rhBMP9 combined with a bovine-derived natural bone mineral scaffold compared to rhBMP2 Clin Oral Implants Res 2017 28(4):381-387 PubMed ID: 26988608 DOI: 10.1111/clr.12804

14442 Fujioka-Kobayashi M, Schaler B, Shirakata Y, Nakamura T, Noguchi K, Zhang Y, Miron RJ. Comparison of Two Porcine Collagen Membranes Combined with rhBMP-2 and rhBMP-9 on Osteoblast Behavior In Vitro Int J Oral Maxillofac Implants 2017 32(4):e221-e230 PubMed ID: 28708926 DOI: 10.11607/jomi.5652

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9332 Joji Kusuyama, Kenjiro Bandow, Mitsuo Shamoto, Kyoko Kakimoto, Tomokazu Ohnishi, Tetsuya Matsuguchi Low Intensity Pulsed Ultrasound (LIPUS) Influences the Multilineage Differentiation of Mesenchymal Stem and Progenitor Cell Lines Through ROCK-Cot/Tpl2-MEK-ERK Signaling Pathway J Biol Chem 2014 289(15):10330-44 PubMed ID: 24550383 DOI: 10.1074/jbc.M113.546382

9336 Ken-ichiro Tanaka, Hiroshi Kaji, Toru Yamaguchi, Ippei Kanazawa, Lucie Canaff, Geoffrey N Hendy, Toshitsugu Sugimoto Involvement of the Osteoinductive Factors, Tmem119 and BMP-2, and the ER Stress Response PERK-eIF2α-ATF4 Pathway in the Commitment of Myoblastic Into Osteoblastic Cells Calcif Tissue Int 2014 94(4):454-64 PubMed ID: 24362451 DOI: 10.1007/s00223-013-9828-1

9345 Sunao Takeshita, Toshio Fumoto, Yoshinori Naoe, Kyoji Ikeda Age-related Marrow Adipogenesis Is Linked to Increased Expression of RANKL J Biol Chem 2014 289(24):16699-710 PubMed ID: 24753250 DOI: 10.1074/jbc.M114.547919

9347 Jinlu Dai, Honglai Zhang, Andreas Karatsinides, Jill M Keller, Kenneth M Kozloff, Dana T Aftab, Frauke Schimmoller, Evan T Keller Cabozantinib Inhibits Prostate Cancer Growth and Prevents Tumor-Induced Bone Lesions Clin Cancer Res 2014 20(3):617-30 PubMed ID: 24097861 DOI: 10.1158/1078-0432.CCR-13-0839

9348 W Ariyoshi, T Okinaga, C B Knudson, W Knudson, T Nishihara High Molecular Weight Hyaluronic Acid Regulates Osteoclast Formation by Inhibiting Receptor Activator of NF-κB Ligand Through Rho Kinase Osteoarthritis Cartilage 2014 22(1):111-20 PubMed ID: 24185105 DOI: 10.1016/j.joca.2013.10.013

9350 Masakazu Notsu, Toru Yamaguchi, Kyoko Okazaki, Ken-ichiro Tanaka, Noriko Ogawa, Ippei Kanazawa, Toshitsugu Sugimoto Advanced Glycation End Product 3 (AGE3) Suppresses the Mineralization of Mouse Stromal ST2 Cells and Human Mesenchymal Stem Cells by Increasing TGF-β Expression and Secretion Endocrinology 2014 155(7):2402-10 PubMed ID: 24758301 DOI: 10.1210/en.2013-1818

9352 Kiyoshi Mori, Riko Kitazawa, Takeshi Kondo, Michiko Mori, Yasuhiro Hamada, Michiru Nishida, Yasuhiro Minami, Ryuma Haraguchi, Yutaka Takahashi, Sohei Kitazawa Diabetic Osteopenia by Decreased β-Catenin Signaling Is Partly Induced by Epigenetic Derepression of sFRP-4 Gene PLoS One 2014 9(7):e102797 PubMed ID: 25036934 DOI: 10.1371/journal.pone.0102797

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9278 Shingen Nakamura, Hirokazu Miki, Shinsuke Kido, Ayako Nakano, Masahiro Hiasa, Asuka Oda, Hiroe Amou, Keiichiro Watanabe, Takeshi Harada, Shiro Fujii, Kyoko Takeuchi, Kumiko Kagawa, Shuji Ozaki, Toshio Matsumoto, Masahiro Abe Activating Transcription Factor 4, an ER Stress Mediator, Is Required For, but Excessive ER Stress Suppresses Osteoblastogenesis by Bortezomib Int J Hematol 2013 98(1):66-73 PubMed ID: 23708974 DOI: 10.1007/s12185-013-1367-z

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8139 Cody JJ, Rivera AA, Lyons GR, Yang SW, Wang M, Sarver DB, Wang D, Selander KS, Kuo HC, Meleth S, Feng X, Siegal GP, Douglas JT. Arming a replicating adenovirus with osteoprotegerin reduces the tumor burden in a murine model of osteolytic bone metastases of breast cancer. Cancer Gene Ther. 2010 17:893-905 PubMed ID: 20798695 DOI: 10.1038/cgt.2010.47

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8493 Kurtova AV, Balakrishnan K, Chen R, Ding W, Schnabl S, Quiroga MP, Sivina M, Wierda WG, Estrov Z, Keating MJ, Shehata M, Jager U, Gandhi V, Kay NE, Plunkett W, Burger JA. Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance. Blood 2009 114:4441-50 PubMed ID: 19762485 DOI: 10.1182/blood-2009-07-233718

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8584 Tanaka T, Kawashima H, Ohnishi K, Matsumura K, Yoshimura R, Matsuyama M, Kuratsukuri K, Nakatani T. Indirect antitumor effects of bisphosphonates on prostatic LNCaP cells co-cultured with bone cells. Anticancer Res. 2009 29:1089-94 PubMed ID: 19414350

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8766 Yamachika E, Tsujigiwa H, Shirasu N, Ueno T, Sakata Y, Fukunaga J, Mizukawa N, Yamada M, Sugahara T. Immobilized recombinant human bone morphogenetic protein-2 enhances the phosphorylation of receptor-activated Smads. J Biomed Mater Res A 2009 88:599-607 PubMed ID: 18314893 DOI: 10.1002/jbm.a.31833

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6530 Anada T, Kumagai T, Honda Y, Masuda T, Kamijo R, Kamakura S, Yoshihara N, Kuriyagawa T, Shimauchi H, Suzuki O. Dose-dependent osteogenic effect of octacalcium phosphate on mouse bone marrow stromal cells. Tissue Eng Part A 2008 14(6):965-78 PubMed ID: 19230123 DOI: 10.1089/tea.2007.0339

7863 Maehira F1, Iinuma Y, Eguchi Y, Miyagi I, Teruya S. Effects of soluble silicon compound and deep-sea water on biochemical and mechanical properties of bone and the related gene expression in mice. J Bone Miner Metab 2008 26(5):446-55 PubMed ID: 18758902 DOI: 10.1007/s00774-007-0845-x

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7920 Hagiwara H, Sugizaki T, Tsukamoto Y, Senoh E, Goto T, Ishihara Y. Effects of alkylphenols on bone metabolism in vivo and in vitro. Toxicol Lett 2008 181(1):13-8 PubMed ID: 18621119 DOI: 10.1016/j.toxlet.2008.06.863

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7073 Tsubaki M, Kato C, Manno M, Ogaki M, Satou T, Itoh T, Kusunoki T, Tanimori Y, Fujiwara K, Matsuoka H, Nishida S. Macrophage inflammatory protein-1alpha (MIP-1alpha) enhances a receptor activator of nuclear factor kappaB ligand (RANKL) expression in mouse bone marrow stromal cells and osteoblasts through MAPK and PI3K/Akt pathways. Mol Cell Biochem 2007 304(1-2):53-60 PubMed ID: 17549607 DOI: 10.1007/s11010-007-9485-7

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7391 Horiuchi K, Miyamoto T, Takaishi H, Hakozaki A, Kosaki N, Miyauchi Y, Furukawa M, Takito J, Kaneko H, Matsuzaki K, Morioka H, Blobel CP, Toyama Y. Cell surface colony-stimulating factor 1 can be cleaved by TNF-alpha converting enzyme or endocytosed in a clathrin-dependent manner. J Immunol 2007 179(10):6715-24 PubMed ID: 17982061 DOI: 10.4049/jimmunol.179.10.6715

7392 Niikura K, Nakajima S, Takano M, Yamazaki H. FR177995, a novel vacuolar ATPase inhibitor, exerts not only an inhibitory effect on bone destruction but also anti-immunoinflammatory effects in adjuvant-induced arthritic rats. Bone 2007 40(4):888-94 PubMed ID: 17157574 DOI: 10.1016/j.bone.2006.10.015

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6151 Nagayoshi K, Ohkawa H, Yorozu K, Higuchi M, Higashi S, Kubota N, Fukui H, Imai N, Gojo S, Hata J, Kobayashi Y, Umezawa A. Increased mobilization of c-kit+ Sca-1+ Lin- (KSL) cells and colony-forming units in spleen (CFU-S) following de novo formation of a stem cell niche depends on dynamic, but not stable, membranous ossification. J Cell Physiol 2006 208(1):188-94 PubMed ID: 16575918 DOI: 10.1002/jcp.20652

6493 Shinoda Y, Yamaguchi M, Ogata N, Akune T, Kubota N, Yamauchi T, Terauchi Y, Kadowaki T, Takeuchi Y, Fukumoto S, Ikeda T, Hoshi K, Chung UI, Nakamura K, Kawaguchi H. Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways. J Cell Biochem 2006 99(1):196-208 PubMed ID: 16598753 DOI: 10.1002/jcb.20890

6997 Sugama R, Koike T, Imai Y, Nomura-Furuwatari C, Takaoka K. Bone morphogenetic protein activities are enhanced by 3',5'-cyclic adenosine monophosphate through suppression of Smad6 expression in osteoprogenitor cells. Bone 2006 38(2):206-14 PubMed ID: 16203197 DOI: 10.1016/j.bone.2005.08.006

7012 Shirakawa K, Maeda S, Gotoh T, Hayashi M, Shinomiya K, Ehata S, Nishimura R, Mori M, Onozaki K, Hayashi H, Uematsu S, Akira S, Ogata E, Miyazono K, Imamura T. CCAAT/enhancer-binding protein homologous protein (CHOP) regulates osteoblast differentiation. Mol Cell Biol 2006 26(16):6105-16 PubMed ID: 16880521 DOI: 10.1128/MCB.02429-05

7024 Shin HH, Kim SJ, Kang SY, Lee DS, Choi HS. Soluble glucocorticoid-induced tumor necrosis factor receptor stimulates osteoclastogenesis by down-regulation of osteoprotegerin in bone marrow stromal cells. Bone 2006 39(4):716-23 PubMed ID: 16750437 DOI: 10.1016/j.bone.2006.03.015

12830 Ohno T, Okahashi N, Kawai S, Kato T, Inaba H, Shibata Y, Morisaki I, Abiko Y, Amano A. Proinflammatory gene expression in mouse ST2 cell line in response to infection by Porphyromonas gingivalis Microbes Infect 2006 8(4):1025-34 PubMed ID: 16476562 DOI: 10.1016/j.micinf.2005.10.021

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3294 Deshimaru, Ryota, Ishitani, Ken, Makita, Kazuya, Horiguchi, Fumi, Nozawa, Shiro Analysis of fatty acid composition in human bone marrow aspirates. Keio J Med 2005 54:150-5 PubMed ID: 16237277 DOI: 10.2302/kjm.54.150

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3366 Oursler, Merry Jo, Bradley, Elizabeth W, Elfering, Sarah L, Giulivi, Cecilia Native, not nitrated, cytochrome c and mitochondria-derived hydrogen peroxide drive osteoclast apoptosis. Am J Physiol Cell Physiol 2005 288:C156-68 PubMed ID: 15342339 DOI: 10.1152/ajpcell.00092.2004

3183 Hata, Kenji, Nishimura, Riko, Ueda, Mio, Ikeda, Fumiyo, Matsubara, Takuma, Ichida, Fumitaka, Hisada, Kunihiro, Nokubi, Takashi, Yamaguchi, Akira, Yoneda, Toshiyuki A CCAAT/enhancer binding protein beta isoform, liver-enriched inhibitory protein, regulates commitment of osteoblasts and adipocytes. Mol Cell Biol 2005 25:1971-9 PubMed ID: 15713650 DOI: 10.1128/MCB.25.5.1971-1979.2005

2843 Takeuchi, Tamotsu, Adachi, Yoshihiro, Ohtsuki, Yuji Skeletrophin, a novel ubiquitin ligase to the intracellular region of Jagged-2, is aberrantly expressed in multiple myeloma. Am J Pathol 2005 166:1817-26 PubMed ID: 15920166 DOI: 10.1016/S0002-9440(10)62491-1

3377 Hall, Christopher L, Bafico, Anna, Dai, Jinlu, Aaronson, Stuart A, Keller, Evan T Prostate cancer cells promote osteoblastic bone metastases through Wnts. Cancer Res 2005 65:7554-60 PubMed ID: 16140917 DOI: 10.1158/0008-5472.CAN-05-1317

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6877 Liu J, Yang H, Liu W, Cao X, Feng X. Sp1 and Sp3 regulate the basal transcription of receptor activator of nuclear factor kappa B ligand gene in osteoblasts and bone marrow stromal cells. J Cell Biochem 2005 96(4):716-27 PubMed ID: 16052479 DOI: 10.1002/jcb.20569

2871 Notoya M, Otsuka E, Yamaguchi A, Hagiwara H Runx-2 is not essential for the vitamin D-regulated expression of RANKL and osteoprotegerin in osteoblastic cells. Biochem Biophys Res Commun 2004 324:655-60 PubMed ID: 15474477 DOI: 10.1016/j.bbrc.2004.09.101

2910 Fan, Xian, Roy, Eileen, Zhu, Liping, Murphy, Tamara C, Ackert-Bicknell, Cheryl, Hart, C Michael, Rosen, Clifford, Nanes, Mark S, Rubin, Janet Nitric oxide regulates receptor activator of nuclear factor-kappaB ligand and osteoprotegerin expression in bone marrow stromal cells. Endocrinology 2004 145:751-9 PubMed ID: 14563699 DOI: 10.1210/en.2003-0726

2926 French, Dorothy M, Kaul, Raji J, D'Souza, Aloma L, Crowley, Craig W, Bao, Min, Frantz, Gretchen D, Filvaroff, Ellen H, Desnoyers, Luc WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair. Am J Pathol 2004 165:855-67 PubMed ID: 15331410 DOI: 10.1016/S0002-9440(10)63348-2

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6662 Fratzl-Zelman N, Glantschnig H, Rumpler M, Nader A, Ellinger A, Varga F. The expression of matrix metalloproteinase-13 and osteocalcin in mouse osteoblasts is related to osteoblastic differentiation and is modulated by 1,25-dihydroxyvitamin D3 and thyroid hormones. Cell Biol Int 2003 27(6):459-68 PubMed ID: 12798773 DOI: 10.1016/s1065-6995(03)00037-4

6696 Maeda T, Kawane T, Horiuchi N. Statins augment vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation. Endocrinology 2003 144(2):681-92 PubMed ID: 12538631 DOI: 10.1210/en.2002-220682

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2518 Yoneda S, Itoh D, Kuroda S, Kondo H, Umezawa A, Ohya K, Ohyama T, Kasugai S. The effects of enamel matrix derivative (EMD) on osteoblastic cells in culture and bone regeneration in a rat skull defect J Periodontal Res 2003 38(3):333-42 PubMed ID: 12753373 DOI: 10.1034/j.1600-0765.2003.00667.x

2773 Sakiyama H, Nonaka T, Masuda R, Inoue N, Kuboki Y, Iijima M, Hirabayasi Y, Takahagi M, Yoshida K, Kuriiwa K, Yoshida M, Imajoh-Ohmi S Characterization of mineral deposits formed in cultures of a hamster tartrate-resistant acid phosphatase (TRAP) and alkaline phosphatase (ALP) double-positive cell line (CCP). Cell Tissue Res 2002 309:269-79 PubMed ID: 12172786 DOI: 10.1007/s00441-002-0587-y

2546 Kitazawa, Riko, Kitazawa, Sohei Vitamin D(3) augments osteoclastogenesis via vitamin D-responsive element of mouse RANKL gene promoter. Biochem Biophys Res Commun 2002 290:650-5 PubMed ID: 11785948 DOI: 10.1006/bbrc.2001.6251

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6673 Kuriyama K, Higuchi C, Tanaka K, Yoshikawa H, Itoh K. A novel anti-rheumatic drug, T-614, stimulates osteoblastic differentiation in vitro and bone morphogenetic protein-2-induced bone formation in vivo. Biochem Biophys Res Commun 2002 299(5):903-9 PubMed ID: 12470665 DOI: 10.1016/s0006-291x(02)02754-7

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3990 Takami M, Takahashi N, Udagawa N, Miyaura C, Suda K, Woo JT, Martin TJ, Nagai K, Suda T. Intracellular calcium and protein kinase C mediate expression of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in osteoblasts. Endocrinology 2000 141(12):4711-9 PubMed ID: 11108286 DOI: 10.1210/endo.141.12.7852

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