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細胞材料開発室サイト

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細胞番号 : 細胞名
RCB0222 : NB1RGB  update : 2024/11/28
細胞特性(Comment:英)Normal human skin fibroblast, RCB original
細胞特性(日)当室で新たに培養化されたヒト新生児皮膚由来の正常二倍体線維芽細胞で有限寿命を有する。15、29、36、47、53、61のPDLのロットをそろえてある。提供申し込み時にはPDLも指定のこと。
細胞特性(寄託者記述:英)
細胞特性(寄託者記述:日)
使用条件(英)There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
使用条件(日)基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。
備考(英)
備考(日)
提供申込書類(英) Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 Ohno,T. & Kojima
樹立者 Ohno, T. & Kurita, K.
寄託日 1987
動物種 _human < Mammals
属名 Homo
種名 sapiens
人種 Japanese
性別 Male
3 days
採取組織 skin
細胞分類 normal
初代培養日 1987
細胞寿命 finite
細胞形態 fibroblast-like
Cellosaurus(Expasy) CVCL_J377
細胞培養・検査情報
寄託時情報
ロット情報
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 MEM ALPHA + 10% FBS
抗生物質 Free
継代方法 0.25% Trypsin
継代密度 1 : 4 split
継代・培地交換頻度 Subculture : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ/アコレプラズマ (-)
動物種PCR OK
ウィルス(HIV) (-)
アイソザイム検査 LD, NP
染色体検査 46(50)
個体識別検査 OK
画像情報
寄託時情報
ロット情報
文献情報 Reference(英) 2件
Reference(日) 3件
利用者成果(英) 250件
利用者成果(日) 16件

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Reference(英)
893  Sudo K, Kanno M, Miharada K, Ogawa S, Hiroyama T, Saijo K, Nakamura Y.  Mesenchymal progenitors able to differentiate into osteogenic, chondrogenic, and/or adipogenic cells in vitro are present in most primary fibroblast-like cell populations  Stem Cells  2007  25(7):1610-7  PubMed ID: 17395773   DOI: 10.1634/stemcells.2006-0504
1387  Sasaki T., Kawai K., Saijo-Kurita K., and Ohno T.  Alternative Methods for Draize Test - Simplified Assay for Live/Dead Cells by Measuring LDH Activity  Alternatives to Animal Testing and Experimentation  1991  1:103-103   

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Reference(日)
1544  佐々木哲二, 大野忠夫  LDH活性測定法による細胞毒性試験  FRAGRANCE JOURNAL  1992  20:61-64   
1631  大野忠夫  ヒト皮膚:HS-K,NHSF 46,NB1RGB  生体の科学  1992  43:449   
1418  佐々木哲二, 河合弘二, 西條薫, 大野忠夫  培養細胞を用いたドレイズ試験法の代替:LDH測定法による生/ 死細胞の定量    1990     

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利用者成果(英)
19923  Tanaka T, Takahashi K, Inoue Y, Endo N, Shimoda E, Ueno K, Ichiyanagi T, Ohta T, Ishihara A.  Inhibition of melanoma cell proliferation by strobilurins isolated from mushrooms and their synthetic analogues  Biosci Biotechnol Biochem  2024  Jan 25:zbae006  PubMed ID: 38271595   DOI: 10.1093/bbb/zbae006
21746  Ihara F, Kyan H, Takashima Y, Ono F, Hayashi K, Matsuo T, Igarashi M, Nishikawa Y, Hikosaka K, Sakamoto H, Nakamura S, Motooka D, Yamauchi K, Ichikawa-Seki M, Fukumoto S, Sasaki M, Ikadai H, Kusakisako K, Ohari Y, Yoshida A, Sasai M, Grigg ME, Yamamoto M.  Far-East Asian Toxoplasma isolates share ancestry with North and South/Central American recombinant lineages.  Nat Commun  2024  15(1):4278  PubMed ID: 38778039   DOI: 10.1038/s41467-024-47625-6
21817  Banzragchgarav O, Ariefta NR, Umemiya-Shirafuji R, Myagmarsuren P, Battsetseg B, Battur B, Batkhuu J, Nishikawa Y.  Acaricidal activity of Erigeron acer L. root against Haemaphysalis longicornis and phytochemical profiling by liquid chromatography-tandem mass spectrometry.  J Vet Med Sci  2024    PubMed ID: 38960665   DOI: 10.1292/jvms.24-0090
22171  Matsuo-Takasaki M, Kambayashi S, Hemmi Y, Wakabayashi T, Shimizu T, An Y, Ito H, Takeuchi K, Ibuki M, Kawashima T, Masayasu R, Suzuki M, Kawai Y, Umekage M, Kato TM, Noguchi M, Nakade K, Nakamura Y, Nakaishi T, Nishishita N, Tsukahara M, Hayashi Y.  Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiation.  Elife  2024  12  PubMed ID: 39529479   DOI: 10.7554/eLife.89724
17554  Konstantinos P. Chatzipapas, Ngoc Hoang Tran, Milos Dordevic, Sara Zivkovic, Sara Zein, Wook‐Geun Shin, Dousatsu Sakata, Nathanael Lampe, Jeremy M. C. Brown, Aleksandra Ristic‐Fira, Ivan Petrovic, Ioanna Kyriakou, Dimitris Emfietzoglou, Susanna Guatelli, Sébastien Incerti  Simulation of DNA damage using Geant4‐DNA: an overview of the “molecularDNA” example application  Precision Radiation Oncology  2023  7:4-14    DOI: 10.1002/pro6.1186
19702  Tamura R, Miyoshi H, Imaizumi K, Yo M, Kase Y, Sato T, Sato M, Morimoto Y, Sampetrean O, Kohyama J, Shinozaki M, Miyawaki A, Yoshida K, Saya H, Okano H, Toda M.  Gene therapy using genome-edited iPS cells for targeting malignant glioma  Bioeng Transl Med  2023  8(5): e10406  PubMed ID: 37693056   DOI: 10.1002/btm2.10406
19986  Honda M.  Z-Isomers of lycopene and β-carotene exhibit greater skin-quality improving action than their all-E-isomers  Food Chem  2023  421:135954  PubMed ID: 37137215   DOI: 10.1016/j.foodchem.2023.135954
21010  Shimada M, Tokumiya T, Miyake T, Tsukada K, Kanzaki N, Yanagihara H, Kobayashi J, Matsumoto Y.  Implication of E3 ligase RAD18 in UV-induced mutagenesis in human induced pluripotent stem cells and neuronal progenitor cells.  J Radiat Res  2023    PubMed ID: 36634340   DOI: 10.1093/jrr/rrac099
21111  Chiho M, Ono Y, Hayashi A, Takahashi K, Taniue K, Kakisaka R, Mori M, Ishii T, Sato H, Okada T, Kawabata H, Goto T, Tamamura N, Omori Y, Takahashi K, Katanuma A, Karasaki H, Liss AS, Mizukami Y.  Multiplex digital PCR assay to detect multiple KRAS and GNAS mutations associated with pancreatic carcinogenesis from minimal specimen amounts.  J Mol Diagn  2023    PubMed ID: 36965665   DOI: 10.1016/j.jmoldx.2023.02.007
21169  Imai R, Tamura R, Yo M, Sato M, Fukumura M, Takahara K, Kase Y, Okano H, Toda M.  Neuroprotective effects of genome-edited human iPS cell-derived neural stem/progenitor cells on traumatic brain injury.  Stem Cells  2023    PubMed ID: 37029780   DOI: 10.1093/stmcls/sxad028
21325  Machihara K, Oki S, Maejima Y, Kageyama S, Onda A, Koseki Y, Imai Y, Namba T.  Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts.  iScience  2023  26(7):107113  PubMed ID: 37416477   DOI: 10.1016/j.isci.2023.107113
21374  Hu N, Suzuki M, Masunaga SI, Kashino G, Kinashi Y, Chen YW, Liu Y, Uehara K, Mitsumoto T, Tanaka H, Ono K.  Experimentally determined relative biological effectiveness of cyclotron-based epithermal neutrons designed for clinical BNCT: in vitro study.  J Radiat Res  2023    PubMed ID: 37607589   DOI: 10.1093/jrr/rrad056
21387  Suzuki M, Funayama T, Suzuki M, Kobayashi Y.  Radiation-quality-dependent bystander cellular effects induced by heavy-ion microbeams through different pathways.  J Radiat Res  2023    PubMed ID: 37658690   DOI: 10.1093/jrr/rrad059
21451  Yoshimura T, Manabe C, Nagumo JI, Nagahama T, Sato T, Murakami S.  Taurine accelerates the synthesis of ceramides and hyaluronic acid in cultured epidermis and dermal fibroblasts.  Exp Ther Med  2023  26(5):512  PubMed ID: 37840567   DOI: 10.3892/etm.2023.12211
17520  Abe K, Yamamoto K, Myoda T, Fujii T, Niwa K.  Protective effects of volatile components of aged garlic extract against ultraviolet B-induced apoptosis in human skin fibroblasts  J Food Biochem  2022  46(12):e14482  PubMed ID: 36219767   DOI: 10.1111/jfbc.14482
15890  Ryan H, Bister D, Holliday SA, Boehlein J, Lewis A, Silberman J, Allen JB, Moore E.  Ancestral Background Is Underreported in Regenerative Engineering  Regen Eng Transl Med  2022  8(4):499-503  PubMed ID: 34778512   DOI: 10.1007/s40883-021-00237-8
15920  Evgeniia Borisova, Ken Nishimura, Yuri An, Miho Takami, Jingyue Li, Dan Song, Mami Matsuo-Takasaki, Dorian Luijkx, Shiho Aizawa, Akihiro Kuno, Eiji Sugihara, Taka-aki Sato, Fumiaki Yumoto, Tohru Terada, Koji Hisatake, Yohei Hayashi  Structurally-discovered KLF4 variants accelerate and stabilize reprogramming to pluripotency  iScience  2022  103525  PubMed ID: 35106457   DOI: 10.1016/j.isci.2021.103525
20618  Shimizu T, Matsuo-Takasaki M, Luijkx D, Takami M, Arai Y, Noguchi M, Nakamura Y, Hayata T, Saito MK, Hayashi Y.  Generation of human induced pluripotent stem cell lines derived from four DiGeorge syndrome patients with 22q11.2 deletion.  Stem Cell Res  2022  61:102744  PubMed ID: 35292424   DOI: 10.1016/j.scr.2022.102744
20793  Wang J, Yano S, Xie K, Ohata Y, Hara T.  Genome-Wide RNA Sequencing Analysis in Human Dermal Fibroblasts Exposed to Low-Dose Ultraviolet A Radiation.  Genes (Basel)  2022  13(6)  PubMed ID: 35741736   DOI: 10.3390/genes13060974
21928  Machihara K, Kageyama S, Oki S, Makino H, Sasaki M, Iwahashi H, Namba T.  Lotus germ extract rejuvenates aging fibroblasts via restoration of disrupted proteostasis by the induction of autophagy  Aging (Albany NY)  2022  14(19):7662-7691  PubMed ID: 36170016   DOI: 10.18632/aging.204303
20085  Kase Y, Uzawa K, Wagai S, Yoshimura S, Yamamoto JI, Toeda Y, Okubo M, Eizuka K, Ando T, Nobuchi T, Kawasaki K, Saito T, Iyoda M, Nakashima D, Kasamatsu A, Tanzawa H.  Engineered exosomes delivering specific tumor-suppressive RNAi attenuate oral cancer progression.  Sci Rep  2021  11(1):5897  PubMed ID: 33723306   DOI: 10.1038/s41598-021-85242-1
20435  Miyake T, Kuge M, Matsumoto Y, Shimada M.  α-glucosyl-rutin activates immediate early genes in human induced pluripotent stem cells.  Stem Cell Res  2021  56:102511  PubMed ID: 34455240   DOI: 10.1016/j.scr.2021.102511
20507  Zemmyo D, Yamamoto M, Miyata S.  Efficient Decellularization by Application of Moderate High Hydrostatic Pressure with Supercooling Pretreatment.  Micromachines (Basel)  2021  12(12)  PubMed ID: 34945339   DOI: 10.3390/mi12121486
16802  Sakata D, Suzuki M, Hirayama R, Abe Y, Muramatsu M, Sato S, Belov O, Kyriakou I, Emfietzoglou D, Guatelli S, Incerti S, Inaniwa T.  Performance Evaluation for Repair of HSGc-C5 Carcinoma Cell Using Geant4-DNA  Cancers (Basel)   2021  13(23):6046  PubMed ID: 34885155   DOI: 10.3390/cancers13236046
11737  Iwahashi H, Kawashima Y, Masaki H.  Interleukin-1 alpha derived from ultraviolet B-exposed keratinocytes is associated with a decrease of endocytic collagen receptor Endo180.  Photodermatol Photoimmunol Photomed  2020  36(1):34-41  PubMed ID: 31376337   DOI: 10.1111/phpp.12502
11882  Inaniwa T, Suzuki M, Sato S, Muramatsu M, Noda A, Iwata Y, Kanematsu N, Shirai T, Noda K.  Effect of external magnetic fields on biological effectiveness of proton beams.  Int. J. Radiat. Oncol. Biol. Phys.  2020  106(3):597-603  PubMed ID: 31678633   DOI: 10.1016/j.ijrobp.2019.10.040
10143  Tomoyo Sawada, Thomas E Chater, Yohei Sasagawa, Mika Yoshimura, Noriko Fujimori-Tonou, Kaori Tanaka, Kynon J M Benjamin, Apuã C M Paquola, Jennifer A Erwin, Yukiko Goda, Itoshi Nikaido, Tadafumi Kato  Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids  Mol Psychiatry  2020  25(11):2695-2711  PubMed ID: 32764691   DOI: 10.1038/s41380-020-0844-z
12019  Coelho ALS, Feuser PE, Carciofi BAM, de Andrade CJ, de Oliveira D.  Mannosylerythritol lipids: antimicrobial and biomedical properties.  Appl. Microbiol. Biotechnol.  2020    PubMed ID: 31980917   DOI: 10.1007/s00253-020-10354-z
12062  Yamada Y, Fukuda Y, Sasaki D, Maruyama M, Harashima H.  Development of a nanoparticle that releases nucleic acids in response to a mitochondrial environment.  Mitochondrion  2020    PubMed ID: 32097722   DOI: 10.1016/j.mito.2020.02.009
12977  Abdul Malik N, Mohamed M, Mustafa MZ, Zainuddin A.  In vitro modulation of extracellular matrix genes by stingless bee honey in cellular aging of human dermal fibroblast cells.  J Food Biochem  2020    PubMed ID: 31746481   DOI: 10.1111/jfbc.13098
13122  Ono Y, Hayashi A, Maeda C, Suzuki M, Wada R, Sato H, Kawabata H, Okada T, Goto T, Karasaki H, Mizukami Y, Okumura T.  Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR.  Sci Rep  2020    PubMed ID: 32704002   DOI: 10.1038/s41598-020-69221-6
13170  Suzuki M, Uchihori Y, Kitamura H, Oikawa M, Konishi T.  Biologic Impact of Different Ultra-Low-Fluence Irradiations in Human Fibroblasts.  Life (Basel)  2020    PubMed ID: 32824801   DOI: 10.3390/life10080154
13267  Yamada Y, Maruyama M, Kita T, Usami SI, Kitajiri SI, Harashima H.  The use of a MITO-Porter to deliver exogenous therapeutic RNA to a mitochondrial disease's cell with a A1555G mutation in the mitochondrial 12S rRNA gene results in an increase in mitochondrial respiratory activity.  Mitochondrion  2020    PubMed ID: 33035688   DOI: 10.1016/j.mito.2020.09.008
13350  Zemmyo D, Yamamoto M, Miyata S.  Fundamental Study of Decellularization Method Using Cyclic Application of High Hydrostatic Pressure.  Micromachines (Basel)  2020    PubMed ID: 33203164   DOI: 10.3390/mi11111008
13515  Polouliakh N, Ludwig V, Meguro A, Kawagoe T, Heeb O, Mizuki N.  Alpha-Arbutin Promotes Wound Healing by Lowering ROS and Upregulating Insulin/IGF-1 Pathway in Human Dermal Fibroblast  Front Physiol  2020  11:586843  PubMed ID: 33250779   DOI: 10.3389/fphys.2020.586843
13860  Suzuki M, Yasuda N, Kitamura H.  Lethal and mutagenic bystander effects in human fibroblast cell cultures subjected to low-energy-carbon ions  Int J Radiat Biol  2020  96(2):179-186  PubMed ID: 31633439   DOI: 10.1080/09553002.2020.1683637
13915  Masao SUZUKI Hiroshi MAEZAWA and Noriko USAMI  Chromatid-type aberrations induced by monoenergetic soft X rays with resonance energy of phosphorus K-shell absorption edge  Photon Factory Activity Report   2020  2019 #37   
17481  Kawamura E, Maruyama M, Abe J, Sudo A, Takeda A, Takada S, Yokota T, Kinugawa S, Harashima H, Yamada Y.  Validation of Gene Therapy for Mutant Mitochondria by Delivering Mitochondrial RNA Using a MITO-Porter  Mol Ther Nucleic Acids  2020  20:687-698  PubMed ID: 32388194   DOI: 10.1016/j.omtn.2020.04.004
22195  Hashimoto K, Yamashita K, Enoyoshi K, Dahan X, Takeuchi T, Kori H, Gotoh M.  The effects of coating culture dishes with collagen on fibroblast cell shape and swirling pattern formation  J Biol Phys  2020  46(4):351-369  PubMed ID: 32860547   DOI: 10.1007/s10867-020-09556-3
11435  Iwasawa C, Tamura R, Sugiura Y, Suzuki S, Kuzumaki N, Narita M, Suematsu M, Nakamura M, Yoshida K, Toda M, Okano H, Miyoshi H.  Increased Cytotoxicity of Herpes Simplex Virus Thymidine Kinase Expression in Human Induced Pluripotent Stem Cells.  Int J Mol Sci  2019    PubMed ID: 30769780   DOI: 10.3390/ijms20040810
11637  Kobayashi Y, Cordonier CEJ, Noda Y, Nagase F, Enomoto J, Kageyama T, Honma H, Maruo S, Fukuda J.  Tailored cell sheet engineering using microstereolithography and electrochemical cell transfer.  Sci Rep  2019    PubMed ID: 31320678   DOI: 10.1038/s41598-019-46801-9
11867  Ginting TE, Christian S, Larasati YO, Suryatenggara J, Suriapranata IM, Mathew G.  Antiviral interferons induced by Newcastle disease virus (NDV) drive a tumor-selective apoptosis.  Sci Rep  2019    PubMed ID: 31641164   DOI: 10.1038/s41598-019-51465-6
11875  Shimada M, Tsukada K, Kagawa N, Matsumoto Y.  Reprogramming and differentiation-dependent transcriptional alteration of DNA damage response and apoptosis genes in human induced pluripotent stem cells.  J. Radiat. Res.  2019    PubMed ID: 31665364   DOI: 10.1093/jrr/rrz057
11880  Machihara K, Namba T.  BAP31 Inhibits Cell Adaptation to ER Stress Conditions, Negatively Regulating Autophagy Induction by Interaction with STX17.  Cells  2019    PubMed ID: 31671609   DOI: 10.3390/cells8111350
10103  Tomoko Miyake, Mikio Shimada, Yoshihisa Matsumoto, Akitoshi Okino  DNA Damage Response After Ionizing Radiation Exposure in Skin Keratinocytes Derived From Human-Induced Pluripotent Stem Cells  Int J Radiat Oncol Biol Phys .  2019  105(1):193-205  PubMed ID: 31085283   DOI: 10.1016/j.ijrobp.2019.05.006
10688  Noriko Yaekashiwa, Hisa Yoshida, Sato Otsuki, Shin’ichiro Hayashi and Kodo Kawase  Verification of Non-thermal Effects of 0.3–0.6 THz-Waves on Human Cultured Cells  Photonics  2019  6(1):33    DOI: 10.3390/photonics6010033
11064  Hiroshi Shimoda, Junji Tanaka, Kaori Zaiki, Koichi Nakaoji  Tiliroside, a Constituent of Strawberry Seeds, Slightly Enhances Hyaluronan Production via Hyaluronan Synthase 2 Expression in Mouse Skin and Human Fibroblasts  Int J Biomed Sci  2019  15:24-31   
12525  Inaniwa T, Suzuki M, Sato S, Noda A, Iwata Y, Kanematsu N, Shirai T, Noda K.  Enhancement of biological effectiveness of carbon-ion beams by applying a longitudinal magnetic field  Int J Radiat Biol  2019  95(6):720-724  PubMed ID: 30652933   DOI: 10.1080/09553002.2019.1569774
12526  Inaniwa T, Suzuki M, Sato S, Noda A, Muramatsu M, Iwata Y, Kanematsu N, Shirai T, Noda K.  Influence of a perpendicular magnetic field on biological effectiveness of carbon-ion beams  Int J Radiat Biol  2019  95(9):1346-1350.  PubMed ID: 31140908   DOI: 10.1080/09553002.2019.1625461
10673  Someya T, Sano K, Hara K, Sagane Y, Watanabe T, Wijesekara RGS.  Fibroblast and keratinocyte gene expression following exposure to extracts of neem plant (Azadirachta indica).  Data Brief  2018  16:982-992  PubMed ID: 29322079   DOI: 10.1016/j.dib.2017.12.035
10677  Yaekashiwa N, Otsuki S, Hayashi S, Kawase K.  Investigation of the non-thermal effects of exposing cells to 70-300 GHz irradiation using a widely tunable source.  J. Radiat. Res.  2018  59:116-121  PubMed ID: 29281029   DOI: 10.1093/jrr/rrx075
10761  Uto T, Tung NH, Ohta T, Juengsanguanpornsuk W, Hung LQ, Hai NT, Long DD, Thuong PT, Okubo S, Hirata S, Shoyama Y.  Antiproliferative activity and apoptosis induction by trijuganone C isolated from the root of Salvia miltiorrhiza Bunge (Danshen).  Phytother Res  2018  32:657-666  PubMed ID: 29464799   DOI: 10.1002/ptr.6013
10819  Mizuno M, Yaekashiwa N, Watanabe S.  Analysis of dermal composite conditions using collagen absorption characteristics in the THz range.  Biomed Opt Express  2018  9:2277-2283  PubMed ID: 29760986   DOI: 10.1364/BOE.9.002277
11263  Sano K, Kawanobe H, Someya T.  Effect of cupuassu butter on human skin cells.  Data Brief  2018    PubMed ID: 30370321   DOI: 10.1016/j.dib.2018.10.026
11266  Tezuka T, Ota A, Karnan S, Matsuura K, Yokoo K, Hosokawa Y, Vigetti D, Passi A, Hatano S, Umezawa K, Watanabe H.  The plant alkaloid conophylline inhibits matrix formation of fibroblasts.  J. Biol. Chem.  2018    PubMed ID: 30377255   DOI: 10.1074/jbc.RA118.005783
11339  Yonezawa T, Momota R, Iwano H, Zhao S, Hakozaki T, Soh C, Sawaki S, Toyama K, Oohashi T.  Unripe peach (Prunus persica) extract ameliorates damage from UV irradiation and improved collagen XVIII expression in 3D skin model.  J Cosmet Dermatol  2018    PubMed ID: 30548159   DOI: 10.1111/jocd.12841
4430  Shigeo Takashima, Kayoko Toyoshi, Nobuyuki Shimozawa  Analyses of the fatty acid separation principle using liquid chromatography-mass spectrometry  Medical Mass Spectrometry  2018  2    DOI: 10.24508/mms.2018.06.002
4431  Noriko Yaekashiwa et al  Verification of the non-thermal effects of THz-wave on human cells  IEEE Xplore  2018  29 October     DOI: 10.1109/IRMMW-THz.2018.8510457
4306  Someya T, Sano K, Hara K, Sagane Y, Watanabe T, Wijesekara RGS.  Fibroblast and keratinocyte gene expression following exposure to the extracts of holy basil plant (Ocimum tenuiflorum), malabar nut plant (Justicia adhatoda), and emblic myrobalan plant (Phyllanthus emblica).  Data Brief  2018    PubMed ID: 29876372   DOI: 10.1016/j.dib.2017.12.055
4307  Sano K, Someya T, Hara K, Sagane Y, Watanabe T, Wijesekara RGS.  Effect of traditional plants in Sri Lanka on skin fibroblast cell number.  Data Brief  2018    PubMed ID: 29900360   DOI: 10.1016/j.dib.2018.05.019
5667  Masao SUZUKI and Noriko USAMI   Cell-killing effect by the targeted cytoplasmic irradiation in normal human fibroblasts with monochromatic X-ray microbeams (2)  Photon Factory Activity Report   2018  36   
5683  Horie M et al  TBX4 is involved in the super-enhancer-driven transcriptional programs underlying features specific to lung fibroblasts.  Am J Physiol Lung Cell Mol Physiol  2018  314(1):L177-L191  PubMed ID: 28971975   DOI: 10.1152/ajplung.00193.2017
5687  Neil F. Johnson  Pulmonary Toxicity of Benzalkonium Chloride  Journal of Aerosol Medicine and Pulmonary Drug Delivery  2018  311-17.  PubMed ID: 28683210   DOI: 10.1089/jamp.2017.1390
5688  Sano K, Gotoh M1, Dodo K, Tajima N, Shimizu Y, Murakami-Murofushi K.  Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts.  Hum Cell  2018  31(1):72-77  PubMed ID: 29063508   DOI: 10.1007/s13577-017-0185-7
5689  Warashina T, Miyase T.  New 8,12;8,20-diepoxy-8,14-secopregnane hexa- and hepta-glycosides from the roots of Asclepias tuberosa.  J Nat Med  2018  72(1):347-356  PubMed ID: 29177792   DOI: 10.1007/s11418-017-1155-9
5690  Iñiguez-Moreno M, Avila-Novoa MG, Gutiérrez-Lomelí M.  Resistance of pathogenic and spoilage microorganisms to disinfectants in the presence of organic matter and their residual effect on stainless steel and polypropylene.  J Glob Antimicrob Resist  2018  197-201  PubMed ID: 29698753   DOI: 10.1016/j.jgar.2018.04.010
10021  Kanemaru A, Yamamoto K, Kawaguchi M, Fukushima T, Lin CY, Johnson MD, Camerer E, Kataoka H.  Deregulated matriptase activity in oral squamous cell carcinoma promotes the infiltration of cancer-associated fibroblasts by paracrine activation of protease-activated receptor 2.  Int. J. Cancer  2017  140:130-141  PubMed ID: 27615543   DOI: 10.1002/ijc.30426
10059  Takashima S, Toyoshi K, Itoh T, Kajiwara N, Honda A, Ohba A, Takemoto S, Yoshida S, Shimozawa N.  Detection of unusual very-long-chain fatty acid and ether lipid derivatives in the fibroblasts and plasma of patients with peroxisomal diseases using liquid chromatography-mass spectrometry.  Mol. Genet. Metab.  2017  120:255-268  PubMed ID: 28089346   DOI: 10.1016/j.ymgme.2016.12.013
10431  Tamura I, Shirafuta Y, Jozaki K, Kajimura T, Shinagawa M, Maekawa R, Taketani T, Asada H, Sato S, Tamura H, Sugino N.  Novel Function of a Transcription Factor WT1 in Regulating Decidualization in Human Endometrial Stromal Cells and Its Molecular Mechanism.  Endocrinology  2017  158:3696-3707  PubMed ID: 28977591   DOI: 10.1210/en.2017-00478
10435  Tung NH, Uto T, Hai NT, Li G, Shoyama Y.  Quassinoids from the Root of Eurycoma longifolia and Their Antiproliferative Activity on Human Cancer Cell Lines.  Pharmacogn Mag  2017  13:459-462  PubMed ID: 28839372   DOI: 10.4103/pm.pm_353_16
10516  Bashar MK, Hashimoto K, Gotoh M, Kori H.  Analyzing orientation patterns of human skin fibroblasts using image gradient information.  Conf Proc IEEE Eng Med Biol Soc  2017  2017:600-603  PubMed ID: 29059944   DOI: 10.1109/EMBC.2017.8036896
10582  Nobeyama Y, Watanabe Y, Nakagawa H.  Silencing of G0/G1 switch gene 2 in cutaneous squamous cell carcinoma.  PLoS ONE  2017  12:e0187047  PubMed ID: 29073263   DOI: 10.1371/journal.pone.0187047
10995    Distinction of dermal conditions related to collagen state using THz spectroscopy  2017 42nd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)  2017      DOI: 10.1109/IRMMW-THz.2017.8067197
5679  Autsavapromporn N, Liu C, Konishi T.  Impact of Co-Culturing with Fractionated Carbon-Ion-Irradiated Cancer Cells on Bystander Normal Cells and Their Progeny.  Radiat Res  2017  188(3):335-341  PubMed ID: 28686544   DOI: 10.1667/RR14773.1
5680  Ginting TE, Suryatenggara J, Christian S, Mathew G.  Proinflammatory response induced by Newcastle disease virus in tumor and normal cells.  Oncolytic Virother  2017  6:21-30  PubMed ID: 28293547   DOI: 10.2147/OV.S123292
5681  Keisuke CCHIBA, Azuma SUZUKI, Shogo MIYATA  Effected of UV Irradiation on Material Properties of In Vitro Cell-Based Skin Model  The Proceedings of Mechanical Engineering Congress, Japan  2017      DOI: 10.1299/jsmemecj.2017.J0250204
5682  Yamauchi K, Mitsunaga T, Afroze SH, Uddin MN.  Structure-Activity Relationships of Methylquercetin on Anti-migration and Anti-proliferation Activity in B16 Melanoma Cells.  Anticancer Res  2017  37(4):1575-1579  PubMed ID: 28373417   DOI: 10.21873/anticanres.11487
5684  Futami 1, Sato K, Miyazaki K, Suzuki K, Nakamura T, Tojo A.  Efficacy and Safety of Doubly-Regulated Vaccinia Virus in a Mouse Xenograft Model of Multiple Myeloma.  Mol Ther Oncolytics  2017  6:57-68  PubMed ID: 28808676   DOI: 10.1016/j.omto.2017.07.001
5686  Michaelidesová A, Vachelová J, Puchalska M, Brabcová KP, Vondráček V, Sihver L, Davídková M  Relative biological effectiveness in a proton spread-out Bragg peak formed by pencil beam scanning mode.  Australas Phys Eng Sci Med  2017  40(2):359-368  PubMed ID: 28321635   DOI: 10.1007/s13246-017-0540-8
14732  Sakamoto N, Ogawa M, Sadamoto K, Takeuchi M, Kataoka N.  Interleukin-6 blockade attenuates lung cancer tissue construction integrated by cancer stem cells  Sci Rep  2017  7(1):12317  PubMed ID: 31719867   DOI: 10.1007/s12195-017-0487-6
9771  Li JR, Suzuki T, Nishimura H, Kishima M, Maeda S, Suzuki H.  Asymmetric Regulation of Peripheral Genes by Two Transcriptional Regulatory Networks.  PLoS ONE  2016  11:e0160459  PubMed ID: 27483142   DOI: 10.1371/journal.pone.0160459
9830  Yoshino A, Polouliakh N, Meguro A, Takeuchi M, Kawagoe T, Mizuki N.  Chum salmon egg extracts induce upregulation of collagen type I and exert antioxidative effects on human dermal fibroblast cultures.  Clin Interv Aging  2016  11:1159-68  PubMed ID: 27621603   DOI: 10.2147/CIA.S102092
9844  Horie M, Yamaguchi Y, Saito A, Nagase T, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Forrest AR, Hayashizaki Y, Suzutani T, Kappert K, Micke P, Ohshima M.  Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis.  Sci Rep  2016  6:33666  PubMed ID: 27645561   DOI: 10.1038/srep33666
5665  Verkhovtsev A, Surdutovich E, Solov'yov AV.  Multiscale approach predictions for biological outcomes in ion-beam cancer therapy.  Sci Rep  2016  6:27654  PubMed ID: 27297618   DOI: 10.1038/srep27654
5666  Katsuhisa Yamada ; Masahiro Suzuki ; Michiyasu Nomura ; Yuji Shibata ; Chiaki Imada  Cell viability of human fibroblasts cultured with various ratios of calcium and magnesium and effects of deep seawater supplementation  IEEE  2016  6-8    DOI: 10.1109/Techno-Ocean.2016.7890653
5668  Ohba T, Ishisaka M, Tsujii S, Tsuruma K, Shimazawa M, Kubo K, Umigai N, Iwawaki T, Hara H.  Crocetin protects ultraviolet A-induced oxidative stress and cell death in skin in vitro and in vivo.  Eur J Pharmacol  2016  789:244-253  PubMed ID: 27452919   DOI: 10.1016/j.ejphar.2016.07.036
5669  Kwofie KD et al  Antitrypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth.  Antimicrob Agents Chemother  2016  60(6):3283-90  PubMed ID: 26953191   DOI: 10.1128/AAC.01916-15
5670  H Oesten S Loeck S Helmbrecht F Tillner P Wohlfahrt J Schuemann A Luehr  SU‐F‐T‐682: In‐Vivo Simulation of the Relative Biological Effectiveness in Proton Therapy Using a Monte Carlo Method  Medical Physics  2016  43:3621-3621    DOI: 10.1118/1.4956868
5672  Nobeyama Y, Nakagawa H.  Aberrant demethylation and expression of MAGEB2 in a subset of malignant peripheral nerve sheath tumors from neurofibromatosis type 1.  J Dermatol Sci.  2016  81(2):118-23  PubMed ID: 26642794   DOI: 10.1016/j.jdermsci.2015.11.004
5673  Yamaba H, Haba M, Kunita M, Sakaida T, Tanaka H, Yashiro Y, Nakata S.  Morphological change of skin fibroblasts induced by UV Irradiation is involved in photoaging.  Exp Dermatol  2016  Suppl 3:45-51  PubMed ID: 27539902   DOI: 10.1111/exd.13084
5674  Keisuke CHIBA, Shogo MIYATA  Effected of UV Irradiation on Mechanical Property of Skin Cell-Seeded Collagen Gel  The Proceedings of Mechanical Engineering Congress, Japan  2016      DOI: 10.1299/jsmemecj.2016.S0220102
5676  Azuma SUZUKI, Shogo MIYATA  Effects of growth factors on contraction process of three-dimensional dermis reconstruction model  The Proceedings of Mechanical Engineering Congress, Japan  2016      DOI: 10.1299/jsmemecj.2016.J0270205
14089  Enomoto J, Mochizuki N, Ebisawa K, Osaki T, Kageyama T, Myasnikova D, Nittami T, Fukuda J.  Engineering thick cell sheets by electrochemical desorption of oligopeptides on membrane substrates  Regen Ther  2016  3:24-31  PubMed ID: 31245469   DOI: 10.1016/j.reth.2015.12.003
7135  Saito Y, Tsuruma K, Ichihara K, Shimazawa M, Hara H.  Brazilian green propolis water extract up-regulates the early expression level of HO-1 and accelerates Nrf2 after UVA irradiation.  BMC Complement Altern Med  2015  15:421  PubMed ID: 26611539   DOI: 10.1186/s12906-015-0945-4
7296  Uto T, Tung NH, Appiah-Opong R, Aning A, Morinaga O, Edoh D, Nyarko AK, Shoyama Y.  Antiproliferative and Pro-Apoptotic Activity of Diarylheptanoids Isolated from the Bark of Alnus japonica in Human Leukemia Cell Lines.  Am. J. Chin. Med.  2015  43:757-67  PubMed ID: 26119959   DOI: 10.1142/S0192415X15500470
7303  Kobayashi H, Nobeyama Y, Nakagawa H.  Tumor-suppressive effects of natural-type interferon-β through CXCL10 in melanoma.  Biochem. Biophys. Res. Commun.  2015  464:416-21  PubMed ID: 26102027   DOI: 10.1016/j.bbrc.2015.06.122
7536  K Shikano, K Chiba, S Miyata  Response of Human Skin Fibroblasts to Mechanical Stretch in Wound Healing Process Analyzed Using a Three-Dimensional Culture Model.  Advanced Biomedical Engineering  2015  4:170?178    DOI: 10.14326/abe.4.170
7574  Yuji SHIBATA, Katsuhisa YAMADA, Chiaki IMADA, Takeshi KOBAYASHI, Takeshi TERAHARA  Phenotypic Characterization of a Microbe Producing Substances for Oxidative Stress Resistance Isolated from the Deep Seawater in Izu-Akazawa, Japan.  Deep Ocean Water Research  2015  15:117-124   
5645  Tomita M, Maeda M.  Mechanisms and biological importance of photon-induced bystander responses: do they have an impact on low-dose radiation responses.  J Radiat Res  2015  56(2):205-19  PubMed ID: 25361549   DOI: 10.1093/jrr/rru099
5651  Suzuki M et al  New anti-trypanosomal active tetracyclic iridoid isolated from Morinda lucida Benth.  Bioorg Med Chem Lett  2015  25(15):3030-3  PubMed ID: 26048790   DOI: 10.1016/j.bmcl.2015.05.003
5652  Tokuyama E, Nagai Y, Takahashi K, Kimata Y, Naruse K.  Mechanical Stretch on Human Skin Equivalents Increases the Epidermal Thickness and Develops the Basement Membrane.  PLoS One  2015  10(11):e0141989  PubMed ID: 26528823   DOI: 10.1371/journal.pone.0141989
5653  Tabata A, Ohkubo Y, Anyoji N, Hojo K, Tomoyasu T, Tatematsu Y, Ohkura K, Nagamune H.  Development of a Sortase A-mediated Peptide-labeled Liposome Applicable to Drug-delivery Systems.  Anticancer Res  2015  35(8):4411-7  PubMed ID: 26168480  
5654  Sadahira Y, Sugihara T, Fujiwara H, Nishimura H, Suetsugu Y, Takeshita M, Okamura S, Goto M.  WRN protein as a novel erythroblast immunohistochemical marker with applications for the diagnosis of Werner syndrome.  Virchows Arch  2015  466(3):343-50  PubMed ID: 25503078   DOI: 10.1007/s00428-014-1703-6
5656  Autsavapromporn N, Plante I, Liu C, Konishi T, Usami N, Funayama T, Azzam EI, Murakami T, Suzuki M.  Genetic changes in progeny of bystander human fibroblasts after microbeam irradiation with X-rays, protons or carbon ions: the relevance to cancer risk.  Int J Radiat Biol  2015  91(1):62-70  PubMed ID: 25084840   DOI: 10.3109/09553002.2014.950715
5655  Khayrul Bashar et al  Pattern quantification from human skin fibroblast images: Image quantification for fibroblast chracterization  IEEE  2015  28-30    DOI: 10.1109/ICIIBMS.2015.7439540
5658  Shirai A1, Onitsuka M, Maseda H, Omasa T.  Effect of polyphenols on reactive oxygen species production and cell growth of human dermal fibroblasts after irradiation with ultraviolet-A light.  Biocontrol Sci  2015  20(1):27-33  PubMed ID: 25817810   DOI: 10.4265/bio.20.27
5660  Morita R, Suzuki M, Kasahara H, Shimizu N, Shichita T, Sekiya T, Kimura A, Sasaki K, Yasukawa H, Yoshimura A.  ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells.  Proc Natl Acad Sci U S A.   2015  112(1):160-5  PubMed ID: 25540418   DOI: 10.1073/pnas.1413234112
5661  Jain I, Kumar V, Satyanarayana T.  Xylooligosaccharides: an economical prebiotic from agroresidues and their health benefits.  Indian J Exp Biol  2015  53(3):131-42  PubMed ID: 25872243  
5663  Quartuccio SM, Schindler K.  Functions of Aurora kinase C in meiosis and cancer.  Front Cell Dev Biol  2015  3:50  PubMed ID: 26347867   DOI: 10.3389/fcell.2015.00050
15214  Md. Khayrul Bashar, Kei Hashimoto, Kanako Enoyoshi, Kimiko Yamashita, Mari Gotoh and Hiroshi Kori  Quantification of Interaction between Human Skin Fibroblasts and Collagen by Image Texture Analysis  Journal of Bioinformatics and Neuroscience (JBINS)  2015  1:31-37   
5529  Maeda-Sano K, Gotoh M, Morohoshi T, Someya T, Murofushi H, Murakami-Murofushi K.   Cyclic phosphatidic acid and lysophosphatidic acid induce hyaluronic acid synthesis via CREB transcription factor regulation in human skin fibroblasts.  Biochim Biophys Acta  2014  1841(9):1256-63  PubMed ID: 24845645   DOI: 10.1016/j.bbalip.2014.05.004
5641  Tomaru Y, Hasegawa R, Suzuki T, Sato T4 Kubosaki A1, Suzuki M, Kawaji H, Forrest AR, Hayashizaki Y; FANTOM Consortium, Shin JW, Suzuki H.  A transient disruption of fibroblastic transcriptional regulatory network facilitates trans-differentiation.  Nucleic Acids Res  2014  2(14):8905-13  PubMed ID: 25013174   DOI: 10.1093/nar/gku567
5642  Narongchai Autsavapromporn, Masao Suzuki, Cuihua Liu, Takeshi Murakami  Short- and long-term effects from the communication between carbon-irradiated cancer cells and non-irradiated human cells: implication for radiotherapy and space radiation  Journal of Radiation Research  2014  55, i52–i53    DOI: 10.1093/jrr/rrt153
5643  Ishikawa K, Ishikawa A, Shoji Y, Imai T.  A genotoxic stress-responsive miRNA, miR-574-3p, delays cell growth by suppressing the enhancer of rudimentary homolog gene in vitro.  Int J Mol Sci  2014  15(2):2971-90  PubMed ID: 24566139   DOI: 10.3390/ijms15022971
5644  Kuse Y, Ogawa K, Tsuruma K, Shimazawa M, Hara H.  Damage of photoreceptor-derived cells in culture induced by light emitting diode-derived blue light.  Sci Rep  2014  4:5223  PubMed ID: 24909301   DOI: 10.1038/srep05223
5633  Tung NH, Suzuki M, Uto T, Morinaga O, Kwofie KD, Ammah N, Koram KA, Aboagye F, Edoh D, Yamashita T, Yamaguchi Y, Setsu T, Yamaoka S, Ohta N, Shoyama Y.  Anti-trypanosomal activity of diarylheptanoids isolated from the bark of Alnus japonica.  Am J Chin Med  2014  42(5):1245-60  PubMed ID: 25178281   DOI: 10.1142/S0192415X14500785
5646  Samuel Tetteh, David. K. Dodoo, Regina AppiahOpong, Isaac Tuffou  Cytotoxicity, antioxidant and glutathione S-transferase inhibitory activity of palladium(II) chloride complexes bearing nucleobase ligands  Transition Met Chem  2014  39:667–674    DOI: 10.1007/s11243-014-9848-3
5647  Hara M, Fujii T, Hashizume R, Nomura Y.  Effect of strain on human dermal fibroblasts in a three-dimensional collagen sponge.  Cytotechnology  2014  66(5):723-8  PubMed ID: 24096838   DOI: 10.1007/s10616-013-9638-3
5648  Adachi H, Murakami Y, Tanaka H, Nakata S.  Increase of stratifin triggered by ultraviolet irradiation is possibly related to premature aging of human skin.  Exp Dermatol  2014  Suppl 1:32-6  PubMed ID: 25234834   DOI: 10.1111/exd.12390
5649  Hara M, Nakashima M, Fujii T, Uehara K, Yokono C, Hashizume R, Nomura Y.  Construction of collagen gel scaffolds for mechanical stress analysis.  Biosci Biotechnol Biochem  2014  78(3):458-61  PubMed ID: 25036833   DOI: 10.1080/09168451.2014.882749
15807  Nishimura K, Kato T, Chen C, Oinam L, Shiomitsu E, Ayakawa D, Ohtaka M, Fukuda A, Nakanishi M, Hisatake K.  Manipulation of KLF4 expression generates iPSCs paused at successive stages of reprogramming  Stem Cell Reports  2014  3(5):915-29  PubMed ID: 25418733   DOI: 10.1016/j.stemcr.2014.08.014
5628  Autsavapromporn N, Suzuki M, Plante I, Liu C, Uchihori Y, Hei TK, Azzam EI, Murakami T.  Participation of gap junction communication in potentially lethal damage repair and DNA damage in human fibroblasts exposed to low- or high-LET radiation.  Mutat Res  2013  756(1-2):78-85  PubMed ID: 23867854   DOI: 10.1016/j.mrgentox.2013.07.001
5629  Tabata A, Ohkubo Y, Tamura M, Tomoyasu T, Ohkura K, Nagamune H.  Construction of an improved drug delivery system tool with enhanced versatility in cell-targeting.  Anticancer Res  2013  33(7):2905-10  PubMed ID: 23780978  
5630  Wada M, Suzuki M, Liu C, Kaneko Y, Fukuda S, Ando K, Matsufuji N.  Modeling the biological response of normal human cells, including repair processes, to fractionated carbon beam irradiation.  J Radiat Res  2013  54(5):798-807  PubMed ID: 23449640   DOI: 10.1093/jrr/rrt012
5631  Uto T, Sakamoto A, Tung NH, Fujiki T, Kishihara K, Oiso S, Kariyazono H, Morinaga O, Shoyama Y.  Anti-Proliferative Activities and Apoptosis Induction by Triterpenes Derived from Eriobotrya japonica in Human Leukemia Cell Lines.  Int J Mol Sci  2013  14(2):4106-20  PubMed ID: 23429195   DOI: 10.3390/ijms14024106
5632  Murase H, Shimazawa M1, Kakino M2, Ichihara K3, Tsuruma K1, Hara H1.  The Effects of Brazilian Green Propolis against Excessive Light-Induced Cell Damage in Retina and Fibroblast Cells.  Evid Based Complement Alternat Med.  2013  2013:238279  PubMed ID: 24416064   DOI: 10.1155/2013/238279
5634  Autsavapromporn N, Suzuki M, Funayama T, Usami N, Plante I, Yokota Y, Mutou Y, Ikeda H, Kobayashi K, Kobayashi Y, Uchihori Y, Hei TK, Azzam EI, Murakami T.  Gap junction communication and the propagation of bystander effects induced by microbeam irradiation in human fibroblast cultures: the impact of radiation quality.  Radiat Res  2013  180(4):367-75  PubMed ID: 23987132   DOI: 10.1667/RR3111.1
5635  Tung NH, Uto T, Sakamoto A, Hayashida Y, Hidaka Y, Morinaga O, Lhieochaiphant S, Shoyama Y.  Antiproliferative and apoptotic effects of compounds from the flower of Mammea siamensis (Miq.) T. Anders. on human cancer cell lines.  Bioorg Med Chem Lett  2013  23(1):158-62  PubMed ID: 23206866   DOI: 10.1016/j.bmcl.2012.10.127
5636  Yamaguchi K, He S, Li Z, Murata K, Hitomi N, Mozumi M, Ariga R, Enomoto T.  Quantification of major royal jelly protein 1 in fresh royal jelly by indirect enzyme-linked immunosorbent assay.  Biosci Biotechnol Biochem  2013  77(6):1310-2  PubMed ID: 23748766   DOI: 10.1271/bbb.130013
5637  Shirai A, Endo T, Maseda H, Omasa T.  Synthesis of thiazole derivatives and evaluation of their antiamoebic activity and cytotoxicity.  Biocontrol Sci  2013  18(4):183-91  PubMed ID: 24366623   DOI: 10.4265/bio.18.183
5638  Shirai A, Fumoto Y, Shouno T, Maseda H, Omasa T.  Synthesis and biological activity of thiazolyl-acetic acid derivatives as possible antimicrobial agents.  Biocontrol Sci  2013  18(2):59-73  PubMed ID: 23796637   DOI: 10.4265/bio.18.59
5640  Mairani A, Böhlen TT, Dokic I, Cabal G, Brons S, Haberer T.  Modelling of cell killing due to sparsely ionizing radiation in normoxic and hypoxic conditions and an extension to high LET radiation.  Int J Radiat Biol  2013  89(10):782-93  PubMed ID: 23627742   DOI: 10.3109/09553002.2013.800247
19134  Tamura I, Asada H, Maekawa R, Tanabe M, Lee L, Taketani T, Yamagata Y, Tamura H, Sugino N.  Induction of IGFBP-1 expression by cAMP is associated with histone acetylation status of the promoter region in human endometrial stromal cells  Endocrinology  2012  153(11):5612-21  PubMed ID: 23011923   DOI: 10.1210/en.2012-1420
5522  Takahashi M, Asikin Y, Takara K, Wada K.  Screening of medicinal and edible plants in Okinawa, Japan, for enhanced proliferative and collagen synthesis activities in NB1RGB human skin fibroblast cells.  Biosci Biotechnol Biochem  2012  76(12):2317-20  PubMed ID: 23221723   DOI: 10.1271/bbb.120478
5619  Makoto Takahashi, Tomotake Morita, Tokuma Fukuoka, Tomohiro Imura, Dai Kitamoto  Glycolipid Biosurfactants, Mannosylerythritol Lipids, Show Antioxidant and Protective Effects against H2O2-Induced Oxidative Stress in Cultured Human Skin Fibroblasts  Journal of Oleo Science  2012  61:457-464  PubMed ID: 22864517   DOI: 10.5650/jos.61.457
5620  Tabata A, Ohkubo Y, Sakakura E, Tomoyasu T, Ohkura K, Nagamune H.  Investigation of a bacterial pore-forming chimera toxin for application as a novel drug-delivery system tool.  Anticancer Res  2012  32(6):2323-9  PubMed ID: 22641669  
5621  Sato T, Watanabe R, Sihver L, Niita K.  Applications of the microdosimetric function implemented in the macroscopic particle transport simulation code PHITS.  Int J Radiat Biol  2012  88(1-2):143-50  PubMed ID: 21823823   DOI: 10.3109/09553002.2011.611216
5622  Takasao N, Tsuji-Naito K, Ishikura S, Tamura A, Akagawa M.  Cinnamon extract promotes type I collagen biosynthesis via activation of IGF-I signaling in human dermal fibroblasts.  J Agric Food Chem  2012  60(5):1193-200  PubMed ID: 22233457   DOI: 10.1021/jf2043357
5624  Maeda R, Ida T, Ihara H, Sakamoto T.  Induction of apoptosis in MCF-7 cells by β-1,3-xylooligosaccharides prepared from Caulerpa lentillifera.  Biosci Biotechnol Biochem  2012  76(5):1032-4  PubMed ID: 22738982   DOI: 10.1271/bbb.120016
5625  Nishiyama Y, Shimada Y, Yokoi T, Kobayashi H, Higuchi T, Eto Y, Ida H, Ohashi T.  Akt inactivation induces endoplasmic reticulum stress-independent autophagy in fibroblasts from patients with Pompe disease.  Mol Genet Metab  2012  107(3):490-5  PubMed ID: 23041259   DOI: 10.1016/j.ymgme.2012.09.011
5626  Suzuki T, Nakano-Ikegaya M, Yabukami-Okuda H, de Hoon M, Severin J, Saga-Hatano S, Shin JW, Kubosaki A, Simon C, Hasegawa Y, Hayashizaki Y, Suzuki H.  Reconstruction of monocyte transcriptional regulatory network accompanies monocytic functions in human fibroblasts.  PLoS One  2012  7(3):e33474  PubMed ID: 22428058   DOI: 10.1371/journal.pone.0033474
5457  Warashina T, Umehara K, Miyase T.  Constituents from the roots of Taraxacum platycarpum and their effect on proliferation of human skin fibroblasts.  Chem Pharm Bull (Tokyo)  2012  60(2):205-12  PubMed ID: 22293479   DOI: 10.1248/cpb.60.205
7780  Sprung CN, Cholewa M, Usami N, Kobayashi K, Crosbie JC.  DNA damage and repair kinetics after microbeam radiation therapy emulation in living cells using monoenergetic synchrotron X-ray microbeams.  J Synchrotron Radiat  2011  18:630-6  PubMed ID: 21685681   DOI: 10.1107/S0909049511011836
19135  Yao M, Yao D, Yamaguchi M, Chida J, Yao D, Kido H.  Bezafibrate upregulates carnitine palmitoyltransferase II expression and promotes mitochondrial energy crisis dissipation in fibroblasts of patients with influenza-associated encephalopathy  Mol Genet Metab  2011  104(3):265-72  PubMed ID: 21816645   DOI: 10.1016/j.ymgme.2011.07.009
5615  Chizuru Tsuruoka  Difference in Biological Effectiveness Due to The Endpoints and Radiation Quality  Biological Sciences in Space  2011  25:13-17    DOI: 10.2187/bss.25.13
5616  Warashina T, Umehara K, Miyase T, Noro T.  8,12;8,20-diepoxy-8,14-secopregnane glycosides from roots of Asclepias tuberosa and their effect on proliferation of human skin fibroblasts.  Phytochemistry  2011  72(14-15):1865-75  PubMed ID: 21703653   DOI: 10.1016/j.phytochem.2011.05.012
5617  Ando Y, Tomaru Y, Morinaga A, Burroughs AM, Kawaji H, Kubosaki A, Kimura R, Tagata M, Ino Y, Hirano H, Chiba J, Suzuki H, Carninci P, Hayashizaki Y.  Nuclear pore complex protein mediated nuclear localization of dicer protein in human cells.  PLoS One  2011  6(8):e23385  PubMed ID: 21858095   DOI: 10.1371/journal.pone.0023385
5524  Yoshimi Tsuruma, Hiroe Maruyama, Yoko Araki  Effect of a Glycoprotein (Apisin) in Royal Jelly on Proliferation and Differentiation in Skin Fibroblast and Osteoblastic Cells  Nippon Shokuhin Kagaku Kogaku Kaishi  2011  58:121-126    DOI: 10.3136/nskkk.58.121
8158  Michikawa Y, Suga T, Ishikawa A, Hayashi H, Oka A, Inoko H, Iwakawa M, Imai T.  Genome wide screen identifies microsatellite markers associated with acute adverse effects following radiotherapy in cancer patients.  BMC Med. Genet.  2010  11:123  PubMed ID: 20701746   DOI: 10.1186/1471-2350-11-123
8280  Tsuruoka C, Furusawa Y, Anzai K, Okayasu R, Suzuki M.  Rejoining kinetics of G1-PCC breaks induced by different heavy-ion beams with a similar LET value.  Mutat. Res.  2010  701:47-51  PubMed ID: 20420934   DOI: 10.1016/j.mrgentox.2010.04.020
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8673  Chizuru Tsuruoka, Masao Suzuki, Yoshiya Furusawa, Kazunori Anzai and Ryuichi Okayasu  The Influence of Mutation Induction in Normal Human Fibroblasts Irradiated with X Rays and Iron Ions  Biological Sciences in Space  2009  23:55-60    DOI: 10.2187/bss.23.55
19001  Ono T, Tsuji T, Sakai M, Yukizaki C, Ino H, Akagi I, Hiramatsu K, Matsumoto Y, Sugiura Y, Uto H, Tsubouchi H, Gohda E.  Induction of hepatocyte growth factor production in human dermal fibroblasts and their proliferation by the extract of bitter melon pulp  Cytokine  2009  46(1):119-26  PubMed ID: 19223201   DOI: 10.1016/j.cyto.2008.12.016
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5606  Satoshi Onoue, Risa Nonaka, Fumiaki Sato, Chiharu Koide, Akinobu Hayashi, Hiroshi Wachi  Involvement of reactive oxygen species in abnormal tropoelastin deposition induced by UVA-photosensitizers  Journal of Health Science  2009  55:946-951    DOI: 10.1248/jhs.55.946
5607  Korcyl M, Waligórski MP.  Track structure effects in a study of cell killing in normal human skin fibroblasts.  Int J Radiat Biol  2009  85(12):1101-13  PubMed ID: 19995236   DOI: 10.3109/09553000903242123
5610  Nobuyuki Hamada  The Bystander Response to Heavy-Ion Radiation: Intercellular Signaling Between Irradiated and Non-Irradiated Cells  Biological Sciences in Space  2009  23:195-201    DOI: 10.2187/bss.23.195
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5598  Tsuruoka C, Suzuki M, Hande MP, Furusawa Y, Anzai K, Okayasu R.  The difference in LET and ion species dependence for induction of initially measured and non-rejoined chromatin breaks in normal human fibroblasts.  Radiat Res  2008  170(2):163-71  PubMed ID: 18666815   DOI: 10.1667/RR1279.1
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2826  Takahagi Y, Fujimura T, Miyagawa S, Nagashima H, Shigehisa T, Shirakura R, Murakami H  Production of alpha 1,3-galactosyltransferase gene knockout pigs expressing both human decay-accelerating factor and N-acetylglucosaminyltransferase III.  Mol Reprod Dev  2005  71:331-8  PubMed ID: 15806557   DOI: 10.1002/mrd.20305
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5580  Yuko Okamoto  Recent Trends of Alternative Methods to Phototoxicity Testing in Japan  Alternatives to Animal Testing and Experimentation  2005  11:39-48    DOI: 10.11232/aatex.11.39
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5568  Yamada H, Murata M, Suzuki K, Koizumi S.  Ultraviolet irradiation increases the sensitivity of cultured human skin cells to cadmium probably through the inhibition of metallothionein gene expression.  Toxicol Appl Pharmacol  2004  200(3):251-7  PubMed ID: 15504461   DOI: 10.1016/j.taap.2004.04.014
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5573  Nakazono-Kusaba A, Takahashi-Yanaga F, Miwa Y, Morimoto S, Furue M, Sasaguri T.  PKC412 induces apoptosis through a caspase-dependent mechanism in human keloid-derived fibroblasts.  Eur J Pharmacol  2004  497(2):155-60  PubMed ID: 15306200   DOI: 10.1016/j.ejphar.2004.06.050
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5557  Hara M, Takanashi Y, Tuzuki N, Kawakami H, Toma K, Higuchi A.  Production of interferon-beta by NB1-RGB cells cultured on peptide-lipid membranes.  Cytotechnology  2003  42(1):13-20  PubMed ID: 19002924   DOI: 10.1023/A:1026157515032
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5560  Ohkura K, Sukeno A, Yamamoto K, Nagamune H, Maeda T, Kourai H.  Analysis of structural features of bis-quaternary ammonium antimicrobial agents 4,4'-(alpha,omega-polymethylenedithio)bis (1-alkylpyridinium iodide)s using computational simulation.  Bioorg Med Chem  2003  11(23):5035-43  PubMed ID: 14604666   DOI: 10.1016/j.bmc.2003.08.027
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5532  田中 信治, 橋爪 論, 土井 浩, 山本 昇  リゾリン脂質による皮膚のヒアルロン酸産生促進効果 (第1報)  日本油化学会誌  1997  469:969-975    DOI: 10.5650/jos1996.46.969
4100  田中 信治, 橋爪 論, 土井 浩, 山本 昇  リゾリン脂質による皮膚のヒアルロン酸産生促進効果 (第2報)  日本油化学会誌  1997  46:977-984    DOI: 10.5650/jos1996.46.977
5539  肥塚 正博, 只左 弘治, 原 聡, 小田 幸子, 谷坂 圭造, 茅原 紘  デキストラン硫酸を用いた初代ヒト癌細胞の選択的培養方法  日本農芸化学会誌  1993  67:1591-1597    DOI: 10.1271/nogeikagaku1924.67.1591



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