CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [RCB0202 : A431]

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22096 Watanabe D, Hiroshima M, Yasui M, Ueda M. Single molecule tracking based drug screening. Nat Commun 2024 15(1):8975 PubMed ID: 39420015 DOI: 10.1038/s41467-024-53432-w

19545 Chinsuwan T, Hirabayashi K, Mishima S, Hasegawa A, Tanaka M, Mochizuki H, Shimoi A, Murakami T, Yagyu S, Shimizu K, Nakazawa Y. Ligand-based, piggyBac-engineered CAR-T cells targeting EGFR are safe and effective against non-small cell lung cancers Mol Ther Oncolytics 2023 31:100728 PubMed ID: 37822488 DOI: 10.1016/j.omto.2023.100728

21008 Zhang A, Abdellatef SA, Nakanishi J. Mechanistic investigation into selective cytotoxic activities of gold nanoparticles functionalized with epidermal growth factor variants. Anal Sci 2023 PubMed ID: 36639559 DOI: 10.1007/s44211-022-00256-7

21088 Tsuruyama T. Kullback-Leibler Divergence of an Open-Queuing Network of a Cell-Signal-Transduction Cascade. Entropy (Basel) 2023 25(2) PubMed ID: 36832692 DOI: 10.3390/e25020326

16738 Soshi Seike, Masaya Takehara, Keiko Kobayashi, Masahiro Nagahama Critical Residues of Clostridium perfringens Delta-Toxin for Oligomerization and Receptor Binding BPB Reports 2022 5:66-69 DOI: 10.1248/bpbreports.5.3_66

20774 Kubota Y, Fujioka Y, Patil A, Takagi Y, Matsubara D, Iijima M, Momose I, Naka R, Nakai K, Noda NN, Takekawa M. Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer. Nat Commun 2022 13(1):4063 PubMed ID: 35831322 DOI: 10.1038/s41467-022-31690-w

20881 Kiso-Farnè K, Tsuruyama T. Epidermal growth factor receptor cascade prioritizes the maximization of signal transduction. Sci Rep 2022 12(1):16950 PubMed ID: 36216834 DOI: 10.1038/s41598-022-20663-0

20954 Ohe S, Kubota Y, Yamaguchi K, Takagi Y, Nashimoto J, Kozuka-Hata H, Oyama M, Furukawa Y, Takekawa M. ERK-mediated NELF-A phosphorylation promotes transcription elongation of immediate-early genes by releasing promoter-proximal pausing of RNA polymerase II. Nat Commun 2022 13(1):7476 PubMed ID: 36463234 DOI: 10.1038/s41467-022-35230-4

20965 Morisaka H, Takaishi M, Akira S, Sano S. Keratinocyte Regnase-1, a down-regulator of skin inflammation, contributes to protection against tumor promotion by limiting COX-2 expression. J Invest Dermatol 2022 PubMed ID: 36470473 DOI: 10.1016/j.jid.2022.11.007

13912 Yamamoto S, Nakanishi J. Epidermal growth factor-gold nanoparticle conjugates-induced cellular responses: Effect of interfacial parameters between cell and nanoparticle Anal Sci 2021 37(5):741-745 PubMed ID: 33390415 DOI: 10.2116/analsci.20SCP16

20118 Abiko Y, Kurosawa K, Yamakawa H, Kumagai Y. Activation of PTP1B/EGFR signaling and cytotoxicity during combined exposure to ambient electrophiles in A431 cells. J Toxicol Sci 2021 46(4),177-185 PubMed ID: 33814511 DOI: 10.2131/jts.46.177

14839 Pascarelli S, Merzhakupova D, Uechi GI, Laurino P. Binding of single-mutant epidermal growth factor (EGF) ligands alters the stability of the EGF receptor dimer and promotes growth signaling J Biol Chem 2021 297(1):100872 PubMed ID: 34126069 DOI: 10.1016/j.jbc.2021.100872

20427 Tsumagari K, Chang CH, Ishihama Y. A protocol for analyzing the protein terminome of human cancer cell line culture supernatants. STAR Protoc 2021 2(3):100682 PubMed ID: 34377995 DOI: 10.1016/j.xpro.2021.100682

20442 Zhang A, Nakanishi J. Improved anti-cancer effect of epidermal growth factor-gold nanoparticle conjugates by protein orientation through site-specific mutagenesis. Sci Technol Adv Mater 2021 22(1):616-626 PubMed ID: 34512175 DOI: 10.1080/14686996.2021.1944783

13433 Setsuko Tsuboi, Takashi Jin Shortwave-infrared (SWIR) fluorescence molecular imaging using indocyanine green–antibody conjugates for the optical diagnostics of cancerous tumours RSC Adv 2020 10(47):28171-28179 PubMed ID: 35519107 DOI: 10.1039/D0RA04710D

13442 Masahiro Nagahama, Keiko Kobayashi, Masaya Takehara The Inhibitory Effect of Cholera Toxin B Subunit on Clostridium Perfringens Iota-Toxin-Induced Cytotoxicity BPB Reports 2020 DOI: 10.1248/bpbreports.3.4_146

13557 Luong NC, Abiko Y, Shibata T, Uchida K, Warabi E, Suzuki M, Noguchi T, Matsuzawa A, Kumagai Y. Redox cycling of 9,10-phenanthrenequinone activates epidermal growth factor receptor signaling through S-oxidation of protein tyrosine phosphatase 1B J Toxicol Sci 2020 45(6):349-36 PubMed ID: 32493877 DOI: 10.2131/jts.45.349

11730 Kobayashi Y, Iwakura Y, Sotoyama H, Kitayama E, Takei N, Someya T, Nawa H. Clozapine-dependent inhibition of EGF/neuregulin receptor (ErbB) kinases. Transl Psychiatry 2019 PubMed ID: 31371697 DOI: 10.1038/s41398-019-0519-1

9926 Setsuko Tsuboia and Takashi Jin BRET based dual-colour (visible/near-infrared) molecular imaging using a quantum dot/EGFP–luciferase conjugate RSC Adv 2019 9:34964-34971 PubMed ID: 35530680 DOI: 10.1039/C9RA07011G

12371 Abiko Y, Nakai Y, Luong NC, Bianco CL, Fukuto JM, Kumagai Y. Interaction of Quinone-Related Electron Acceptors with Hydropersulfide Na 2 S 2: Evidence for One-Electron Reduction Reaction Chem Res Toxicol 2019 32(4):551-556 PubMed ID: 30719914 DOI: 10.1021/acs.chemrestox.8b00158

19254 Kariya Y, Oyama M, Hashimoto Y, Gu J, Kariya Y. β4-Integrin/PI3K Signaling Promotes Tumor Progression through the Galectin-3-N-Glycan Complex. Mol Cancer Res 2018 16(6):1024-1034 PubMed ID: 29549127 DOI: 10.1158/1541-7786.MCR-17-0365

11076 Toyama K, Nomura W, Kobayakawa T, Tamamura H. Delivery of a Proapoptotic Peptide to EGFR-Positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR. Bioconjug. Chem. 2018 29(6):2050-2057 PubMed ID: 29763296 DOI: 10.1021/acs.bioconjchem.8b00250

4126 Osaki T, Nakanishi T, Aoki M, Omizu T, Nishiura D, Kitamura M. Soluble Expression in Escherichia coli of a Single-Domain Antibody-Tumor Necrosis Factor α Fusion Protein Specific for Epidermal Growth Factor Receptor. Monoclon Antib Immunodiagn Immunother 2018 PubMed ID: 29474158 DOI: 10.1089/mab.2017.0051

4467 Toyama K, Kobayakawa T, Nomura W, Tamamura H. Inhibition of EGFR Activation by Bivalent Ligands Based on a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR. Chem. Pharm. Bull. 2018 66(11):1083-1089 PubMed ID: 30381661 DOI: 10.1248/cpb.c18-00539

6021 Hasegawa G, Akatsuka K, Nakashima Y, Yokoe Y, Higo N, Shimonaka M. Tamoxifen inhibits the proliferation of non‑melanoma skin cancer cells by increasing intracellular calcium concentration. Int J Oncol 2018 53(5):2157-2166 PubMed ID: 30226592 DOI: 10.3892/ijo.2018.4548

10236 Sudo K, Niikura K, Iwaki K, Kohyama S, Fujiwara K, Doi N. Human-derived fusogenic peptides for the intracellular delivery of proteins. J Control Release 2017 255:1-11 PubMed ID: 28385674 DOI: 10.1016/j.jconrel.2017.03.398

14029 Shibuya Y, Haga N, Asano R, Nakazawa H, Hattori T, Takeda D, Sugiyama A, Kurotani R, Kumagai I, Umetsu M, Makabe K. Generation of camelid VHH bispecific constructs via in-cell intein-mediated protein trans-splicing Protein Eng Des Sel 2017 30(1):15-21 PubMed ID: 27881685 DOI: 10.1093/protein/gzw057

9117 Soshi Seike, Kazuaki Miyamoto, Keiko Kobayashi, Masaya Takehara, Masahiro Nagahama Clostridium Perfringens Delta-Toxin Induces Rapid Cell Necrosis PLoS One 2016 11 (1), e0147957 PubMed ID: 26807591 DOI: 10.1371/journal.pone.0147957

12681 Toyama K, Mizuguchi T, Nomura W, Tamamura H. Functional evaluation of fluorescein-labeled derivatives of a peptide inhibitor of the EGF receptor dimerization Bioorg Med Chem 2016 24(16):3406-12 PubMed ID: 27283787 DOI: 10.1016/j.bmc.2016.05.026

12872 Niikura K, Horisawa K, Doi N. Endosomal escape efficiency of fusogenic B18 and B55 peptides fused with anti-EGFR single chain Fv as estimated by nuclear translocation J Biochem 2016 159(1):123-32. PubMed ID: 26338729 DOI: 10.1093/jb/mvv083

12936 Hayashida Y, Ikeda Y, Sawada K, Kawai K, Kato T, Kakehi Y, Araki N. Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor Int J Cancer 2016 139(3):700-11 PubMed ID: 26989815 DOI: 10.1002/ijc.30097

12954 Hara-Chikuma M, Watanabe S, Satooka H. Involvement of aquaporin-3 in epidermal growth factor receptor signaling via hydrogen peroxide transport in cancer cells Biochem Biophys Res Commun 2016 471(4):603-9 PubMed ID: 26896765 DOI: 10.1016/j.bbrc.2016.02.010

14093 Batzaya Byambaa, Tomohiro Konno, Kazuhiko Ishihara Photoinduced detachment of cells adhered on 2-methacryloyloxyethyl phosphorylcholine polymer with cell binding molecule through photocleavable linkage Reactive and Functional Polymers 2016 104:30-37 DOI: 10.1016/j.reactfunctpolym.2016.04.018

14188 Daisuke Takahashi, Takashi Nagao, Shota Sotokawa, Kazunobu Toshima Target-selective photo-degradation of a sialyl Lewis a (sLea) conjugate and photo-cytotoxicity against sLea positive cancer cells using an anthraquinone-antibody hybrid MedChemComm 2016 7:1224-1228 DOI: 10.1039/c6md00167j

14308 Osaki T, Wang CX, Tachibana T, Azuma M, Kitamura M, Nakanishi T. Generation and Characterization of Rat Monoclonal Antibodies Against Epidermal Growth Factor Receptor Monoclon Antib Immunodiagn Immunother 2015 34(6):418-22 PubMed ID: 26683181 DOI: 10.1089/mab.2015.0034

14980 Abiko Y, Luong NC, Kumagai Y. A Biotin-PEAC5-maleimide labeling assay to detect electrophiles J Toxicol Sci 2015 40(3):405-11 PubMed ID: 25972200 DOI: 10.2131/jts.40.405

15531 Osaki T, Fujisawa S, Kitaguchi M, Kitamura M, Nakanishi T. Development of a bispecific antibody tetramerized through hetero-associating peptides FEBS J 2015 282(22):4389-401 PubMed ID: 26337767 DOI: 10.1111/febs.13505

15865 Yutaka Hitomi, Toshiyuki Takeyasu, Masahito Kodera Development of Green-Emitting Iron Complex-Based Fluorescent Probes for Intracellular Hydrogen Peroxide Imaging Bulletin of the Chemical Society of Japan 2014 87:819-824 DOI: 10.1246/bcsj.20140055

7928 Shoji Y, Miyamoto M, Ishikawa K, Yoshioka T, Mishra R, Ichinokawa K, Matsumura Y, Itoh T, Shinohara T, Hirano S, Kondo S. The CD40-CD154 interaction would correlate with proliferation and immune escape in pancreatic ductal adenocarcinoma. J Surg Oncol 2011 103:230-8 PubMed ID: 21337550 DOI: 10.1002/jso.21812

7956 Uchino T, Ikarashi Y, Nishimura T. Effects of coating materials and size of titanium dioxide particles on their cytotoxicity and penetration into the cellular membrane. J Toxicol Sci 2011 36:95-100 PubMed ID: 21297346 DOI: 10.2131/jts.36.95

18580 Iijima M, Matsuzaki T, Yoshimoto N, Niimi T, Tanizawa K, Kuroda S. Fluorophore-labeled nanocapsules displaying IgG Fc-binding domains for the simultaneous detection of multiple antigens Biomaterials 2011 32(34):9011-20 PubMed ID: 21864900 DOI: 10.1016/j.biomaterials.2011.08.012

19029 Kanamori-Katayama M, Kaiho A, Ishizu Y, Okamura-Oho Y, Hino O, Abe M, Kishimoto T, Sekihara H, Nakamura Y, Suzuki H, Forrest AR, Hayashizaki Y. LRRN4 and UPK3B are markers of primary mesothelial cells PLoS One 2011 6(10):e25391 PubMed ID: 21984916 DOI: 10.1371/journal.pone.0025391

5355 Kishor Mazumder et al Ursolic acid derivatives from Bangladeshi medicinal plant, Saurauja roxburghii: Isolation and cytotoxic activity against A431 and C6 glioma cell lines Phytochemistry Letters 2011 4:287-291 DOI: 10.1016/j.phytol.2011.04.019

9083 Masahiro Nagahama, Mariko Umezaki, Masataka Oda, Keiko Kobayashi, Shigenobu Tone, Taiji Suda, Kazumi Ishidoh, Jun Sakurai Clostridium Perfringens Iota-Toxin B Induces Rapid Cell Necrosis Infect Immun 2011 79 (11), 4353-60 PubMed ID: 21911469 DOI: 10.1128/IAI.05677-11

13818 Kikuji Yamashita, Shine-Od Dalkhsuren, Tatsuo Ishikawa, Kaori Sumida, Jun Ishibashi, Hiroyoshi Hosokawa, Akemichi Ueno, Fumio Nasu, Seiichiro Kitamura Far Infrared Ray Radiation Inhibits the Proliferation of A549, HSC3 and Sa3 Cancer Cells through Enhancing the Expression of ATF3 Gene Journal of Electromagnetic Analysis and Applications 2010 2:382-394 DOI: 10.4236/jemaa.2010.26050

18312 Podoplanin, a novel marker of tumor-initiating cells in human squamous cell carcinoma A431 Podoplanin, a novel marker of tumor-initiating cells in human squamous cell carcinoma A431 Biochem Biophys Res Commun 2008 373(1):36-41 PubMed ID: 18539139 DOI: 10.1016/j.bbrc.2008.05.163

8749 Matsumoto M, Yamaguchi Y, Seino Y, Hatakeyama A, Takei H, Niikura H, Ito K, Suzuki T, Sasano H, Yaegashi N, Hayashi S. Estrogen signaling ability in human endometrial cancer through the cancer-stromal interaction. Endocr. Relat. Cancer 2008 15:451-63 PubMed ID: 18508998 DOI: 10.1677/ERC-07-0227

18668 Hirano T, Morii H, Nakazawa K, Murakami D, Yamashita A, Asahi J, Orimo H, Tamae K, Tokura Y. Enhancement of adipogenesis induction by conditioned media obtained from cancer cells Cancer Lett 2008 268(2):286-94. PubMed ID: 8490102 DOI: 10.1016/j.canlet.2008.04.005

18766 Taguchi T, Tsukuda M, Imagawa-Ishiguro Y, Kato Y, Sano D. Involvement of EGFR in the response of squamous cell carcinoma of the head and neck cell lines to gefitinib Oncol Rep 2008 19(1):65-71 PubMed ID: 18097577

18869 Hong J, Yokomakura A, Nakano Y, Ishihara K, Kaneda M, Onodera M, Nakahama K, Morita I, Niikura K, Ahn JW, Zee O, Ohuchi K. Inhibition of vacuolar-type (H+)-ATPase by the cytostatic macrolide apicularen A and its role in apicularen A-induced apoptosis in RAW 264.7 cells FEBS Lett 2006 580(11):2723-30 PubMed ID: 16647709 DOI: 10.1016/j.febslet.2006.04.031

17939 Hayashida T, Ueda M, Aiura K, Tada H, Onizuka M, Seno M, Yamada H, Kitajima M. Anti-angiogenic effect of an insertional fusion protein of human basic fibroblast growth factor and ribonuclease-1 Protein Eng Des Sel 2005 18(7):321-7 PubMed ID: 15980015 DOI: 10.1093/protein/gzi040

6452 Tsuji T, Kawada Y, Kai-Murozono M, Komatsu S, Han SA, Takeuchi K, Mizushima H, Miyazaki K, Irimura T. Regulation of melanoma cell migration and invasion by laminin-5 and alpha3beta1 integrin (VLA-3). Clin Exp Metastasis 2002 19(2):127-34 PubMed ID: 11964076 DOI: 10.1023/a:1014573204062

18912 Tanimura A, Tojyo Y, Turner RJ. Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins J Biol Chem 2000 275(35):27488-93 PubMed ID: 10874040 DOI: 10.1074/jbc.M004495200

2371 Sato T, Iwai M, Sakai T, Sato H, Seiki M, Mori Y, Ito A. Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts. Br J Cancer 1999 80(8):1137-43 PubMed ID: 10376963 DOI: 10.1038/sj.bjc.6690477

17256 Takenouchi T, Kadosaka M, Shin SY, Munekata E. Biological actions of the epidermal growth factors-like domain peptides of mouse schwannoma-derived growth factor and human amphiregulin J Pept Res 1999 53(2):120-5 PubMed ID: 10195449 DOI: 10.1034/j.1399-3011.1999.00004.x

2400 Kawase T, Orikasa M, Oguro A, Burns DM. Possible regulation of epidermal growth factor-receptor tyrosine autophosphorylation by calcium and G proteins in chemically permeabilized rat UMR106 cells Arch Oral Biol 1999 44(2):157-71 PubMed ID: 10206334 DOI: 10.1016/s0003-9969(98)00105-8

2438 Ishida A, Sasaguri T, Miwa Y, Kosaka C, Taba Y, Abumiya T. Tumor suppressor p53 but not cGMP mediates NO-induced expression of p21(Waf1/Cip1/Sdi1) in vascular smooth muscle cells Mol Pharmacol 1999 56(5):938-46 PubMed ID: 10531398 DOI: 10.1124/mol.56.5.938

17247 Yasuyuki Suzuki, Yasuhiro Ozawa, Kazuo Murakami, Hitoshi Miyazaki Inhibition of epidermal growth factor-induced stat1 activation by lysophosphatidic acid is mediated by pertussis toxin-sensitive g proteins and tyrosine phosphatase in human epidermoid carcinoma A431 cells IUBMB Life 1998 44:979-987 DOI: 10.1080/15216549800202042

18115 Suzuki Y, Ozawa Y, Murakami K, Miyazaki H. Lysophosphatidic acid inhibits epidermal-growth-factor-induced Stat1 signaling in human epidermoid carcinoma A431 cells Biochem Biophys Res Commun 1997 240(3):856-61 PubMed ID: 9398658 DOI: 10.1006/bbrc.1997.7758

2196 Sato T, Nakajima H, Fujio K, Mori Y. Enhancement of prostaglandin E2 production by epidermal growth factor requires the coordinate activation of cytosolic phospholipase A2 and cyclooxygenase 2 in human squamous carcinoma A431 cells. Prostaglandins 1997 53(5):355-69 PubMed ID: 9247974 DOI: 10.1016/0090-6980(97)00036-1

2069 Okada N, Fushimi M, Nagata Y, Fukunaga T, Tsutsumi Y, Nakagawa S, Mayumi T. Evaluation of angiogenic inhibitors with an in vivo quantitative angiogenesis method using agarose microencapsulation and mouse hemoglobin enzyme-linked immunosorbent assay. Jpn J Cancer Res 1996 87(9):952-7 PubMed ID: 8878458 DOI: 10.1111/j.1349-7006.1996.tb02125.x

17227 Osada H, Kono T, Miwa K, Yamada C. Phorbol-ester-stimulated human lymphoid cell lines produce a plasminogen activator modulator inducing cell-bound urokinase-type plasminogen activator in malignant tumor cell lines Int J Cancer 1996 65(2):178-85 PubMed ID: 8567114 DOI: 10.1002/(SICI)1097-0215(19960117)65:2<178::AID-IJC9>3.0.CO;2-W

17933 Takenouchi T, Kadosaka M, Shin SY, Munekata E. Chemical synthesis and biological activities of the EGF-like domain of mouse schwannoma-derived growth factor (SDGF) Int J Pept Protein Res 1995 46(5):391-6 PubMed ID: 8567183 DOI: 10.1111/j.1399-3011.1995.tb01073.x

17950 Shin SY, Shimizu M, Ohtaki T, Munekata E. Synthesis and biological activity of N-terminal-truncated derivatives of human epidermal growth factor (h-EGF) Peptides 1995 16(2):205-10 PubMed ID: 7784250 DOI: 10.1016/0196-9781(94)00181-2

2068 Okada N, Fushimi M, Nagata Y, Fukunaga T, Tsutsumi Y, Nakagawa S, Mayumi T. A quantative in vivo method of analyzing human tumor-induced angiogenesis in mice using agarose microencapsulation and hemoglobin enzyme-linked immunosorbent assay. Jpn J Cancer Res 1995 86(12):1182-8 PubMed ID: 8636008 DOI: 10.1111/j.1349-7006.1995.tb03313.x

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17903 Oshima M, Sugiyama H, Kitagawa K, Taketo M. APC gene messenger RNA: novel isoforms that lack exon 7 Cancer Res 1993 53(23):5589-91 PubMed ID: 8242607

1504 Hirano Y, Okuno M, Hayashi T, Goto K, Nakajima A. Cell-attachment activities of surface immobilized oligopeptides RGD, RGDS, RGDV, RGDT, and YIGSR toward five cell lines J Biomater Sci Polym Ed 1993 4(3):235-43 PubMed ID: 8476793 DOI: 10.1163/156856293x00546

15582 Yoshiaki Hirano, Motoya Okuno, Toshio Hayashi, Akio Nakajima Liquid-Phase Synthesis and Cell Attachment Activity of Bioactive Pentapeptide YIGSR. Polymer Journal 1992 24:465-472 DOI: 10.1295/polymj.24.465