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Cell No. : Cell Name
RCB0202 : A431  update : 2020/09/24
CommentHigh level of EGF receptor
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, a prior written permission of the DEPOSITOR or the RIKEN BRC is necessary.
Remarks
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
Basic information Depositor Abe, Shin-ichiro
Year of deposit 1987
Animal human < Mammals
Genus Homo
Species sapiens
Gender Female
Age at sampling 85 years
Tissue epidermoid carcinoma
Classification cancer
Lifespan infinite
Morphology epithelial-like
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives DMEM (low glucose) + 10% FBS
Antibiotics Free
Passage method 0.25% trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : once/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR(human) OK
Virus (HIV) (-)
Isozyme LD, NP, G6PD
Chromosome mode 72-82(50) : /74(5),75(7),76(8),77(10),78(7),79(3)/
Images
deposit info
lot info
Reference information Reference 1
User's Publication 19


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Reference
1026  Giard DJ, Aaronson SA, Todaro GJ, Arnstein P, Kersey JH, Dosik H, Parks WP.  In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors.  J Natl Cancer Inst  1973  51(5):1417-23  PubMed ID: 4357758

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User's Publication
10406  D. Merzhakupova, S. Pascarelli, P. Laurino  Epidermal Growth Factor single mutants highlighted by homologs cross-conservation approach differentially affect the EGF Receptor downstream pathway  bioRxiv  2020  2020-7-17 
11376  Ren Q, Mohri K, Warashina S, Wada Y, Watanabe Y, Mukai H.  Improved Immuno-PET Imaging of HER2-Positive Tumors in Mice: Urokinase Injection-Triggered Clearance Enhancement of 64Cu-Trastuzumab.  Mol. Pharm.  2019    PubMed ID: 30633529
11076  Toyama K, Nomura W, Kobayakawa T, Tamamura H.  Delivery of a Proapoptotic Peptide to EGFR-Positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.  Bioconjug. Chem.  2018  29(6):2050-2057  PubMed ID: 29763296
4126  Osaki T, Nakanishi T, Aoki M, Omizu T, Nishiura D, Kitamura M.  Soluble Expression in Escherichia coli of a Single-Domain Antibody-Tumor Necrosis Factor α Fusion Protein Specific for Epidermal Growth Factor Receptor.  Monoclon Antib Immunodiagn Immunother  2018    PubMed ID: 29474158
4467  Toyama K, Kobayakawa T, Nomura W, Tamamura H.  Inhibition of EGFR Activation by Bivalent Ligands Based on a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.  Chem. Pharm. Bull.  2018  66(11):1083-1089  PubMed ID: 30381661
6021  Hasegawa G, Akatsuka K, Nakashima Y, Yokoe Y, Higo N, Shimonaka M.  Tamoxifen inhibits the proliferation of non‑melanoma skin cancer cells by increasing intracellular calcium concentration.  Int J Oncol  2018  53(5):2157-2166  PubMed ID: 30226592
10236  Sudo K, Niikura K, Iwaki K, Kohyama S, Fujiwara K, Doi N.  Human-derived fusogenic peptides for the intracellular delivery of proteins.  J Control Release  2017  255:1-11  PubMed ID: 28385674
9117  Soshi Seike, Kazuaki Miyamoto, Keiko Kobayashi, Masaya Takehara, Masahiro Nagahama  Clostridium Perfringens Delta-Toxin Induces Rapid Cell Necrosis  PLoS One  2016  11 (1), e0147957  PubMed ID: 26807591
7928  Shoji Y, Miyamoto M, Ishikawa K, Yoshioka T, Mishra R, Ichinokawa K, Matsumura Y, Itoh T, Shinohara T, Hirano S, Kondo S.  The CD40-CD154 interaction would correlate with proliferation and immune escape in pancreatic ductal adenocarcinoma.  J Surg Oncol  2011  103:230-8  PubMed ID: 21337550
7956  Uchino T, Ikarashi Y, Nishimura T.  Effects of coating materials and size of titanium dioxide particles on their cytotoxicity and penetration into the cellular membrane.  J Toxicol Sci  2011  36:95-100  PubMed ID: 21297346
5355  ishor Mazumder et al  Ursolic acid derivatives from Bangladeshi medicinal plant, Saurauja roxburghii: Isolation and cytotoxic activity against A431 and C6 glioma cell lines  Phytochemistry Letters  2011  4:287-291 
9083  Masahiro Nagahama, Mariko Umezaki, Masataka Oda, Keiko Kobayashi, Shigenobu Tone, Taiji Suda, Kazumi Ishidoh, Jun Sakurai  Clostridium Perfringens Iota-Toxin B Induces Rapid Cell Necrosis  Infect Immun  2011  79 (11), 4353-60  PubMed ID: 21911469
8749  Matsumoto M, Yamaguchi Y, Seino Y, Hatakeyama A, Takei H, Niikura H, Ito K, Suzuki T, Sasano H, Yaegashi N, Hayashi S.  Estrogen signaling ability in human endometrial cancer through the cancer-stromal interaction.  Endocr. Relat. Cancer  2008  15:451-63  PubMed ID: 18508998
6452  Tsuji T, Kawada Y, Kai-Murozono M, Komatsu S, Han SA, Takeuchi K, Mizushima H, Miyazaki K, Irimura T.  Regulation of melanoma cell migration and invasion by laminin-5 and alpha3beta1 integrin (VLA-3).  Clin Exp Metastasis  2002  19(2):127-34  PubMed ID: 11964076
2371  Sato T, Iwai M, Sakai T, Sato H, Seiki M, Mori Y, Ito A.  Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts.  Br J Cancer  1999  80(8):1137-43  PubMed ID: 10376963
2196  Sato T, Nakajima H, Fujio K, Mori Y.  Enhancement of prostaglandin E2 production by epidermal growth factor requires the coordinate activation of cytosolic phospholipase A2 and cyclooxygenase 2 in human squamous carcinoma A431 cells.  Prostaglandins  1997  53(5):355-69  PubMed ID: 9247974
2069  Okada N, Fushimi M, Nagata Y, Fukunaga T, Tsutsumi Y, Nakagawa S, Mayumi T.  Evaluation of angiogenic inhibitors with an in vivo quantitative angiogenesis method using agarose microencapsulation and mouse hemoglobin enzyme-linked immunosorbent assay.  Jpn J Cancer Res  1996  87(9):952-7  PubMed ID: 8878458
2068  Okada N, Fushimi M, Nagata Y, Fukunaga T, Tsutsumi Y, Nakagawa S, Mayumi T.  A quantative in vivo method of analyzing human tumor-induced angiogenesis in mice using agarose microencapsulation and hemoglobin enzyme-linked immunosorbent assay.  Jpn J Cancer Res  1995  86(12):1182-8  PubMed ID: 8636008
1856  Shinohara Y, Yamamoto K, Kogure K, Ichihara J, Terada H.  Steady state transcript levels of the type II hexokinase and type 1 glucose transporter in human tumor cell lines.  Cancer Lett  1994  82(1):27-32  PubMed ID: 7518342



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