細胞番号 : 細胞名 RCB0160 : CV-1  update : 2024/02/13
細胞特性(Comment:英)			CITES. Monkey cell line derived from kidney. COS-1 and COS-7 are derived from this cell line. Require import and export permits according to the Convention on International Trade in Endangered Species (CITES). Origin animal species details
細胞特性(日)			サル腎由来細胞株。COS-1、COS-7はこの細胞株の亜株。ワシントン条約対象。
細胞特性(寄託者記述:英)
細胞特性(寄託者記述:日)
使用条件(英)			There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
使用条件(日)			基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。
備考(英)
備考(日)
提供申込書類(英)			Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)
			Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日)			依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf
			提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください（詳細）。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料			手数料とお支払いについてはこちらをご覧ください。
細胞基本情報		寄託者	Murakami, Yasufumi
		樹立者	Jensen, F. C.
		寄託日	1987
		動物種	_monkey < Mammals
		動物系統名	African green Origin animal species details
		属名	Cercopithecus
		種名	aethiops
		性別	Male
		齢	adult
		採取組織	kidney
		細胞分類	transformed
		細胞寿命	infinite
		細胞形態	fibroblast-like
		Cellosaurus(Expasy)	CVCL_0229
細胞培養・検査情報			寄託時情報	ロット情報
	培地・試薬情報		培地・試薬一覧はこちらをご覧ください。
		培養形態		Adherent cells
		培地		DMEM (low glucose) + 10% FBS
		抗生物質		Free
		継代方法		0.25% Trypsin
		継代密度		1 : 8 split
		継代・培地交換頻度		Subculture : 2 times/week
		培養最適温度		37 ℃
		二酸化炭素濃度		5 %
		凍結培地		Medium + 10% DMSO
		凍結方法		Slow freezing
		マイコプラズマ		(-)
		動物種PCR		OK
		ウィルス（HIV)		(-)
		アイソザイム検査		LD, NP
		染色体検査		75-89(50) : /84(5),85(9),86(10),87(14),88(6),89(1)
文献情報		Reference(英)	2件
		Reference(日)	0件
		利用者成果(英)	15件
		利用者成果(日)	0件

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Reference(英)

4613  Chakrabarti S, Joffe S, Seidman MM.  Recombination and deletion of sequences in shuttle vector plasmids in mammalian cells.  Mol Cell Biol  1985  5(9):2265-71  PubMed ID: 3869955   DOI: 10.1128/mcb.5.9.2265

952  Jensen, F. C., Girardi, A. J., Gilden, R. V. and Koprowski, H.  Infection of human and simian tissue cultures with Rous sarcoma virus.  Proc Natl Acad Sci U S A  1964  52:53-59  PubMed ID: 14192657   DOI: 10.1073/pnas.52.1.53

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Reference(日)

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利用者成果(英)

20536  Doi M, Morita N, Sakashita M, Okuzawa T, Ohgiya S, Okamoto D, Sato K, Ito Y, Matsuura H, Hashidoko Y.  Pinellic Acid Isolated from Quercetin-rich Onions has a Peroxisome Proliferator-Activated Receptor-Alpha/Gamma (PPAR-α/γ) Transactivation Activity.  Planta Med  2022    PubMed ID: 35038752   DOI: 10.1055/a-1345-9471

11212  Ishibashi H, Kim EY, Arizono K, Iwata H.  In Vitro Assessment of Activation of Baikal Seal ( Pusa sibirica) Peroxisome Proliferator-Activated Receptor α by Polybrominated Diphenyl Ethers.  Environ. Sci. Technol.  2018    PubMed ID: 30212190   DOI: 10.1021/acs.est.8b02501

10941  Yashiro T, Kasakura K, Oda Y, Kitamura N, Inoue A, Nakamura S, Yokoyama H, Fukuyama K, Hara M, Ogawa H, Okumura K, Nishiyama M, Nishiyama C.  The hematopoietic cell-specific transcription factor PU.1 is critical for expression of CD11c  Int Immunol  2017  29:87-94  PubMed ID: 28338898   DOI: 10.1093/intimm/dxx009

12261  Tingting Zhou, Shuyan Cong, Shiying Sun, Hongmiao Sun, Renlong Zou, Shengli Wang, Chunyu Wang, Jiao Jiao, Kiminobu Goto, Hajime Nawata, Toshihiko Yanase, Yue Zhao  Identification of endocrine disrupting chemicals activating SXR-mediated transactivation of CYP3A and CYP7A1  Mol Cell Endocrinol  2013  365(1):36-43  PubMed ID: 22975079   DOI: 10.1016/j.mce.2012.09.001

7626  Kitamura N, Yokoyama H, Yashiro T, Nakano N, Nishiyama M, Kanada S, Fukai T, Hara M, Ikeda S, Ogawa H, Okumura K, Nishiyama C.  Role of PU.1 in MHC class II expression through transcriptional regulation of class II transactivator pI in dendritic cells.  J. Allergy Clin. Immunol.  2012  129:814-824.e6  PubMed ID: 22112519   DOI: 10.1016/j.jaci.2011.10.019

8045  Kanada S, Nishiyama C, Nakano N, Suzuki R, Maeda K, Hara M, Kitamura N, Ogawa H, Okumura K.  Critical role of transcription factor PU.1 in the expression of CD80 and CD86 on dendritic cells.  Blood  2011  117:2211-22  PubMed ID: 21119111   DOI: 10.1182/blood-2010-06-291898

18610  Iwashita A, Muramatsu Y, Yamazaki T, Muramoto M, Kita Y, Yamazaki S, Mihara K, Moriguchi A, Matsuoka N.  Neuroprotective efficacy of the peroxisome proliferator-activated receptor delta-selective agonists in vitro and in vivo  J Pharmacol Exp Ther  2007  320(3):1087-96  PubMed ID: 17167170   DOI: 10.1124/jpet.106.115758

3572  Fujimura T, Kimura C, Oe T, Takata Y, Sakuma H, Aramori I, Mutoh S.  A selective peroxisome proliferator-activated receptor gamma modulator with distinct fat cell regulation properties.  J Pharmacol Exp Ther  2006  318(2):863-71  PubMed ID: 16682454   DOI: 10.1124/jpet.106.102459

2908  Sugatani J, Nishitani S, Yamakawa K, Yoshinari K, Sueyoshi T, Negishi M, Miwa M  Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1.  Mol Pharmacol  2005  67:845-55  PubMed ID: 15557560   DOI: 10.1124/mol.104.007161

3573  Fujimura T, Sakuma H, Konishi S, Oe T, Hosogai N, Kimura C, Aramori I, Mutoh S.  FK614, a novel peroxisome proliferator-activated receptor gamma modulator, induces differential transactivation through a unique ligand-specific interaction with transcriptional coactivators.  J Pharmacol Sci  2005  99(4):342-52  PubMed ID: 16314690   DOI: 10.1254/jphs.fp0050578

2923  Minoura, Hideaki, Takeshita, Shigeru, Ita, Makoto, Hirosumi, Jiro, Mabuchi, Miyuki, Kawamura, Ikuo, Nakajima, Satoko, Nakayama, Osamu, Kayakiri, Hiroshi, Oku, Teruo, Ohkubo-Suzuki, Akiko, Fukagawa, Masao, Kojo, Hitoshi, Hanioka, Kenichi, Yamasaki, Noritsugu, Imoto, Takafumi, Kobayashi, Yoshinori, Mutoh, Seitaro  Pharmacological characteristics of a novel nonthiazolidinedione insulin sensitizer, FK614.  Eur J Pharmacol  2004  494:273-81  PubMed ID: 15212984   DOI: 10.1016/j.ejphar.2004.04.038

2640  Maeda, Keiko, Nishiyama, Chiharu, Tokura, Tomoko, Akizawa, Yushiro, Nishiyama, Makoto, Ogawa, Hideoki, Okumura, Ko, Ra, Chisei  Regulation of cell type-specific mouse Fc epsilon RI beta-chain gene expression by GATA-1 via four GATA motifs in the promoter.  J Immunol  2003  170:334-40  PubMed ID: 12496417   DOI: 10.4049/jimmunol.170.1.334

6163  Makino Y, Yoshikawa N, Okamoto K, Hirota K, Yodoi J, Makino I, Tanaka H.  Direct association with thioredoxin allows redox regulation of glucocorticoid receptor function.  J Biol Chem  1999  274(5):3182-8  PubMed ID: 9915858   DOI: 10.1074/jbc.274.5.3182

18014  Okuno H, Miyashita Y.  Expression of the transcription factor Zif268 in the temporal cortex of monkeys during visual paired associate learning  Eur J Neurosci  1996  8(10):2118-28  PubMed ID: 8921303   DOI: 10.1111/j.1460-9568.1996.tb00733.x

17888  Miyazaki Y, Akizuki S, Sakaoka H, Yamamoto S, Terao H.  Disseminated infection of herpes simplex virus with fulminant hepatitis in a healthy adult. A case report   APMIS  1991  99(11):1001-7  PubMed ID: 1659835   DOI: 10.1111/j.1699-0463.1991.tb01292.x

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